SIMILAR PATTERNS OF AMINO ACIDS FOR 4KMM_A_CHDA503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jax CONSERVED
HYPOTHETICAL PROTEIN

(Archaeoglobus
fulgidus) 		PF03807
(F420_oxidored) 		4 ARG A  82
PRO A  99
SER A 110
TRP A  74
 None
 1.47A 4kmmA-1jaxA:
1.4		 4kmmA-1jaxA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k3v CAPSID PROTEIN VP2

(Ungulate
protoparvovirus
1) 		PF00740
(Parvo_coat) 		4 MET A 133
PRO A 458
SER A 571
TRP A 117
 None
 1.49A 4kmmA-1k3vA:
undetectable		 4kmmA-1k3vA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0q SURFACE LAYER
PROTEIN

(Methanosarcina
mazei) 		PF00801
(PKD)
PF10282
(Lactonase) 		4 PRO A  76
SER A  75
VAL A  48
MET A  35
 None
 1.48A 4kmmA-1l0qA:
undetectable		 4kmmA-1l0qA:
20.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae) 		PF00762
(Ferrochelatase) 		4 ARG A  87
PRO A 238
VAL A 277
TRP A 282
 None
 0.58A 4kmmA-1lbqA:
48.2		 4kmmA-1lbqA:
48.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa4 ENDO-BETA-1,4-GLUCAN
ASE

(Streptomyces
sp. 11AG8) 		PF01670
(Glyco_hydro_12) 		4 PRO A  54
SER A  56
VAL A 131
TRP A 205
 None
 1.32A 4kmmA-1oa4A:
0.0		 4kmmA-1oa4A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ry2 ACETYL-COENZYME A
SYNTHETASE 1

(Saccharomyces
cerevisiae) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 PRO A 530
SER A 531
VAL A 108
TRP A 125
 None
 0.90A 4kmmA-1ry2A:
0.0		 4kmmA-1ry2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su7 CARBON MONOXIDE
DEHYDROGENASE 2

(Carboxydothermus
hydrogenoformans) 		PF03063
(Prismane) 		4 MET A 302
PRO A 263
SER A 266
VAL A 527
 None
 1.31A 4kmmA-1su7A:
1.9		 4kmmA-1su7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkx SAM POINTED
DOMAIN-CONTAINING
ETS TRANSCRIPTION
FACTOR

(Homo sapiens) 		PF02198
(SAM_PNT) 		4 MET A  63
PRO A  24
VAL A  32
TRP A  27
 None
 1.30A 4kmmA-2dkxA:
undetectable		 4kmmA-2dkxA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fja ADENYLYLSULFATE
REDUCTASE, SUBUNIT B

(Archaeoglobus
fulgidus) 		PF12139
(APS-reductase_C)
PF13187
(Fer4_9) 		4 MET B 756
PRO B 779
MET B 787
TRP B 788
 None
 1.11A 4kmmA-2fjaB:
undetectable		 4kmmA-2fjaB:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kfg EH DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF12763
(EF-hand_4) 		4 PRO A 132
SER A 134
VAL A  46
TRP A  44
 None
 1.45A 4kmmA-2kfgA:
undetectable		 4kmmA-2kfgA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 PRO A 440
SER A 441
VAL A 429
TRP A 433
 None
 1.45A 4kmmA-2ongA:
undetectable		 4kmmA-2ongA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5z TYPE VI SECRETION
SYSTEM COMPONENT

(Escherichia
coli) 		PF05954
(Phage_GPD) 		4 ARG X 159
PRO X 373
SER X  38
VAL X 180
 None
 1.48A 4kmmA-2p5zX:
undetectable		 4kmmA-2p5zX:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwq GLUCOSE
DEHYDROGENASE

(Haloferax
mediterranei) 		PF08240
(ADH_N)
PF16912
(Glu_dehyd_C) 		4 PRO A 173
SER A 174
VAL A 268
TRP A 171
 None
 1.50A 4kmmA-2vwqA:
undetectable		 4kmmA-2vwqA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu5 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 ARG A 258
SER A 472
VAL A 289
MET A 294
 None
 1.31A 4kmmA-2wu5A:
undetectable		 4kmmA-2wu5A:
20.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		6 MET A  99
PRO A 266
SER A 268
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.29A 4kmmA-3aqiA:
59.7		 4kmmA-3aqiA:
99.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c10 HISTONE DEACETYLASE
7A

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		4 MET A 783
PRO A 791
SER A 790
VAL A 835
 None
 1.33A 4kmmA-3c10A:
undetectable		 4kmmA-3c10A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5s METHYLENETETRAHYDROF
OLATE--TRNA-(URACIL-
5-)-METHYLTRANSFERAS
E TRMFO

(Thermus
thermophilus) 		PF01134
(GIDA) 		4 ARG A  22
PRO A 369
SER A 373
TRP A 427
 None
 1.46A 4kmmA-3g5sA:
undetectable		 4kmmA-3g5sA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhd FATTY ACID SYNTHASE

(Homo sapiens) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 MET A 140
PRO A 334
SER A 163
VAL A 190
 None
 1.41A 4kmmA-3hhdA:
undetectable		 4kmmA-3hhdA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 ARG B 407
PRO B 215
SER B 213
VAL B 200
 None
 1.39A 4kmmA-3hkzB:
undetectable		 4kmmA-3hkzB:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		4 MET A 324
PRO A 285
SER A 288
VAL A 551
 None
 1.29A 4kmmA-3i04A:
undetectable		 4kmmA-3i04A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikm DNA POLYMERASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 ARG A 288
SER A 296
VAL A 432
MET A 427
 None
 1.32A 4kmmA-3ikmA:
undetectable		 4kmmA-3ikmA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9u V-TYPE PROTON ATPASE
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		no annotation 4 ARG C 179
PRO C 216
SER C  93
TRP C 215
 None
 1.48A 4kmmA-3j9uC:
undetectable		 4kmmA-3j9uC:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksy SON OF SEVENLESS
HOMOLOG 1

(Homo sapiens) 		PF00125
(Histone)
PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		4 PRO A 768
SER A 766
VAL A 761
TRP A 763
 None
 1.49A 4kmmA-3ksyA:
undetectable		 4kmmA-3ksyA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsc TRIAZINE HYDROLASE

(Paenarthrobacter
aurescens) 		PF01979
(Amidohydro_1) 		4 PRO A 210
SER A 161
VAL A 213
MET A 163
 None
 1.46A 4kmmA-3lscA:
undetectable		 4kmmA-3lscA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3m BETA SUBUNIT
2-HYDROXYACYL-COA
DEHYDRATASE

(Clostridioides
difficile) 		PF06050
(HGD-D) 		4 MET B 322
PRO B 327
SER B 292
MET B  98
 None
SF4  B 386 ( 4.5A)
None
None
 1.49A 4kmmA-3o3mB:
undetectable		 4kmmA-3o3mB:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9c CAFFEIC ACID
O-METHYLTRANSFERASE

(Lolium perenne) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 MET A 315
PRO A 150
SER A 136
VAL A 144
 None
 1.29A 4kmmA-3p9cA:
undetectable		 4kmmA-3p9cA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfo PUTATIVE
ACETYLORNITHINE
DEACETYLASE

(Rhodopseudomonas
palustris) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 MET A 136
PRO A 395
SER A 411
VAL A 148
 None
 1.21A 4kmmA-3pfoA:
undetectable		 4kmmA-3pfoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uet ALPHA-1,3/4-FUCOSIDA
SE

(Bifidobacterium
longum) 		PF01120
(Alpha_L_fucos) 		4 PRO A 326
SER A 327
VAL A  64
TRP A  67
 None
 1.35A 4kmmA-3uetA:
undetectable		 4kmmA-3uetA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upy OXIDOREDUCTASE

(Brucella
abortus) 		PF03447
(NAD_binding_3) 		4 MET A 137
PRO A 169
SER A 170
VAL A 231
 None
 1.43A 4kmmA-3upyA:
undetectable		 4kmmA-3upyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3o HYDROGENASE-1 LARGE
SUBUNIT

(Salmonella
enterica) 		PF00374
(NiFeSe_Hases) 		4 ARG A  18
PRO A 541
SER A 403
VAL A  47
 None
 1.40A 4kmmA-4c3oA:
undetectable		 4kmmA-4c3oA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ftw PHOSPHOLIPASE/CARBOX
YLESTERASE

(Rhodobacter
sphaeroides) 		PF02230
(Abhydrolase_2) 		4 MET A 134
PRO A 120
SER A 125
TRP A 121
 None
 1.14A 4kmmA-4ftwA:
3.5		 4kmmA-4ftwA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gp1 POLYPRENYL
SYNTHETASE

(Pyrobaculum
calidifontis) 		PF00348
(polyprenyl_synt) 		4 ARG A 117
SER A 199
VAL A 137
TRP A 195
 None
 1.46A 4kmmA-4gp1A:
undetectable		 4kmmA-4gp1A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iim INTERSECTIN-1

(Homo sapiens) 		PF00018
(SH3_1) 		4 PRO A 962
SER A 964
MET A 948
TRP A 949
 None
 0.93A 4kmmA-4iimA:
undetectable		 4kmmA-4iimA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnm CHITINASE A

(Cycas revoluta) 		PF00704
(Glyco_hydro_18) 		4 PRO A  10
SER A 328
VAL A  14
TRP A   9
 None
 1.28A 4kmmA-4mnmA:
undetectable		 4kmmA-4mnmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofl EXTRACYTOPLASMIC
NICKEL-BINDING
PROTEIN YPYNTA

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		4 PRO A  54
SER A  55
VAL A 124
TRP A  61
 None
 1.47A 4kmmA-4oflA:
undetectable		 4kmmA-4oflA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pgh CAFFEIC ACID
O-METHYLTRANSFERASE

(Sorghum bicolor) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 MET A 317
PRO A 150
SER A 136
VAL A 144
 None
 1.11A 4kmmA-4pghA:
undetectable		 4kmmA-4pghA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q69 PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 ARG A 335
PRO A 425
SER A  66
MET A 422
 GOL  A 503 (-3.4A)
None
None
None
 1.35A 4kmmA-4q69A:
undetectable		 4kmmA-4q69A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4quk DIHYDROFLAVONOL-4-RE
DUCTASE

(Medicago
truncatula) 		PF01370
(Epimerase) 		4 PRO A 192
SER A 130
VAL A 231
MET A 194
 None
 1.13A 4kmmA-4qukA:
2.8		 4kmmA-4qukA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca) 		PF07993
(NAD_binding_4) 		4 PRO A1304
SER A1305
VAL A1317
TRP A1316
 None
 1.46A 4kmmA-4w4tA:
2.6		 4kmmA-4w4tA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aq1 GLUCOSE-6-PHOSPHATE
DEHYDROGENASE

(Trypanosoma
cruzi) 		PF00479
(G6PD_N)
PF02781
(G6PD_C) 		4 MET A 253
PRO A 475
SER A 480
VAL A 472
 None
 1.26A 4kmmA-5aq1A:
4.3		 4kmmA-5aq1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlc PYRIDOXINE
5'-PHOSPHATE
SYNTHASE

(Pseudomonas
aeruginosa) 		PF03740
(PdxJ) 		4 MET A  90
PRO A  99
SER A 139
VAL A  55
 None
 1.18A 4kmmA-5dlcA:
undetectable		 4kmmA-5dlcA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4i PHOSPHOLYASE

(Paenarthrobacter
aurescens) 		PF00202
(Aminotran_3) 		4 ARG A 242
PRO A 219
SER A 255
VAL A 272
 None
 1.34A 4kmmA-5g4iA:
undetectable		 4kmmA-5g4iA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs2 ANTI-REPEBODY
ANTI-MBP

(Mus musculus;
Homo sapiens) 		PF07686
(V-set)
PF07686
(V-set) 		4 ARG H  38
PRO D  14
SER D 121
VAL H  64
 None
 1.27A 4kmmA-5gs2H:
undetectable		 4kmmA-5gs2H:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hha PVDO

(Pseudomonas
aeruginosa) 		PF03781
(FGE-sulfatase) 		4 PRO A 231
SER A 235
MET A 238
TRP A 237
 None
 1.36A 4kmmA-5hhaA:
undetectable		 4kmmA-5hhaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ie6 ZEARALENONE
HYDROLASE

(Clonostachys
rosea) 		PF00561
(Abhydrolase_1) 		4 PRO A 244
SER A 247
VAL A 212
MET A 241
 None
 1.44A 4kmmA-5ie6A:
3.1		 4kmmA-5ie6A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6o PUTATIVE POLYKETIDE
SYNTHASE

(Brevibacillus
brevis) 		PF14765
(PS-DH) 		4 MET A2132
PRO A2163
VAL A2000
TRP A2002
 None
 1.29A 4kmmA-5j6oA:
undetectable		 4kmmA-5j6oA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y4g AMBP3

(Fischerella
ambigua) 		no annotation 4 PRO A 135
SER A 137
VAL A  87
TRP A 214
 None
 1.21A 4kmmA-5y4gA:
undetectable		 4kmmA-5y4gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6acd -

(-) 		no annotation 4 PRO A 710
SER A1003
VAL A 934
MET A 713
 None
 1.37A 4kmmA-6acdA:
undetectable		 4kmmA-6acdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bv2 AMINOPEPTIDASE N

(Sus scrofa) 		no annotation 4 MET A 690
ARG A 480
SER A 698
VAL A 435
 None
SO4  A1030 (-4.6A)
None
None
 1.40A 4kmmA-6bv2A:
undetectable		 4kmmA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elq CARBON MONOXIDE
DEHYDROGENASE

(Carboxydothermus
hydrogenoformans) 		no annotation 4 MET X 302
PRO X 263
SER X 266
VAL X 526
 None
 1.28A 4kmmA-6elqX:
undetectable		 4kmmA-6elqX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		4 ARG A1108
PRO A1050
SER D  32
VAL A1083
 None
 0.84A 4kmmA-6eojA:
undetectable		 4kmmA-6eojA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 PRO A1912
SER A1913
VAL A2504
TRP A2510
 None
 1.49A 4kmmA-6fb3A:
undetectable		 4kmmA-6fb3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 4 ARG B 128
SER B 116
VAL B  78
TRP B  77
 None
 1.01A 4kmmA-6fosB:
undetectable		 4kmmA-6fosB:
undetectable