SIMILAR PATTERNS OF AMINO ACIDS FOR 4K50_E_ACTE503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpd CREB-BINDING
PROTEIN,CELLULAR
TUMOR ANTIGEN P53
FUSION PROTEIN

(Homo sapiens;
Mus musculus) 		PF02135
(zf-TAZ)
PF08563
(P53_TAD) 		4 MET A1799
SER A1779
LEU A1826
CYH A1776
 None
 1.43A 4k50E-5hpdA:
undetectable		 4k50E-5hpdA:
14.29