SIMILAR PATTERNS OF AMINO ACIDS FOR 4JSL_A_H4BA502
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kex | NEUROPILIN-1 (Homo sapiens) |
PF00754(F5_F8_type_C) | 4 | ARG A 130TRP A 97PHE A 131GLU A 95 | None | 1.42A | 4jslA-1kexA:0.04jslB-1kexA:0.0 | 4jslA-1kexA:15.514jslB-1kexA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | ARG A 340TRP A 155PHE A 156GLU A 154 | None | 1.32A | 4jslA-1l5jA:0.04jslB-1l5jA:0.0 | 4jslA-1l5jA:20.214jslB-1l5jA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrk | YGFZ PROTEIN (Escherichiacoli) |
PF01571(GCV_T) | 4 | VAL A 200ARG A 160TRP A 27PHE A 154 | NoneNoneSO4 A 400 (-3.4A)SO4 A 400 (-4.6A) | 1.31A | 4jslA-1nrkA:0.04jslB-1nrkA:0.0 | 4jslA-1nrkA:21.244jslB-1nrkA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zvd | SMAD UBIQUITINATIONREGULATORY FACTOR 2 (Homo sapiens) |
PF00632(HECT) | 4 | VAL A 397TRP A 441PHE A 485GLU A 405 | None | 1.44A | 4jslA-1zvdA:0.04jslB-1zvdA:0.0 | 4jslA-1zvdA:22.914jslB-1zvdA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d52 | PENTAKETIDE CHROMONESYNTHASE (Aloearborescens) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | VAL A 52ARG A 81PHE A 83GLU A 87 | None | 1.35A | 4jslA-2d52A:0.74jslB-2d52A:0.8 | 4jslA-2d52A:21.894jslB-2d52A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 4 | VAL A 23ARG A 116PHE A 29GLU A 27 | None | 1.25A | 4jslA-2incA:0.04jslB-2incA:0.0 | 4jslA-2incA:20.594jslB-2incA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rtt | CHIC (Streptomycescoelicolor) |
PF00553(CBM_2) | 4 | VAL A 37TRP A 22PHE A 41GLU A 38 | None | 1.39A | 4jslA-2rttA:0.04jslB-2rttA:0.0 | 4jslA-2rttA:15.254jslB-2rttA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xqx | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D (Streptococcuspneumoniae) |
PF00754(F5_F8_type_C) | 4 | VAL A 811TRP A 840PHE A 816GLU A 826 | None | 1.48A | 4jslA-2xqxA:0.04jslB-2xqxA:0.0 | 4jslA-2xqxA:15.234jslB-2xqxA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5h | GLUCOCORTICOIDRECEPTOR DNA-BINDINGFACTOR 1 (Homo sapiens) |
PF00071(Ras) | 4 | VAL A 67ARG A 44PHE A 134GLU A 142 | NoneUNX A 305 (-4.1A)NoneNone | 1.50A | 4jslA-3c5hA:0.04jslB-3c5hA:0.0 | 4jslA-3c5hA:18.814jslB-3c5hA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1n | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
PF00632(HECT) | 4 | VAL A4019TRP A4065PHE A4109GLU A4033 | None | 1.31A | 4jslA-3g1nA:undetectable4jslB-3g1nA:undetectable | 4jslA-3g1nA:21.684jslB-3g1nA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k77 | DNA REPAIR PROTEINXRCC1 (Homo sapiens) |
PF01834(XRCC1_N) | 4 | VAL A 89ARG A 109PHE A 93GLU A 69 | None | 1.44A | 4jslA-3k77A:undetectable4jslB-3k77A:undetectable | 4jslA-3k77A:15.354jslB-3k77A:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lcc | PUTATIVE METHYLCHLORIDE TRANSFERASE (Arabidopsisthaliana) |
PF05724(TPMT) | 4 | VAL A 120ARG A 69PHE A 133GLU A 122 | None | 1.31A | 4jslA-3lccA:undetectable4jslB-3lccA:undetectable | 4jslA-3lccA:18.044jslB-3lccA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vv4 | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Thermosynechococcuselongatus) |
PF01590(GAF) | 4 | VAL A 72TRP A 71PHE A 67GLU A 73 | NonePVG A 201 (-3.6A)NoneNone | 1.07A | 4jslA-3vv4A:undetectable4jslB-3vv4A:1.7 | 4jslA-3vv4A:19.964jslB-3vv4A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8c | HSC70-INTERACTINGPROTEIN (Rattusnorvegicus) |
no annotation | 4 | VAL A 35TRP A 34PHE A 30GLU A 36 | None | 1.49A | 4jslA-4j8cA:undetectable4jslB-4j8cA:undetectable | 4jslA-4j8cA:8.454jslB-4j8cA:8.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6x | ANKYRIN-3 (Homo sapiens) |
PF00531(Death) | 4 | VAL A 71ARG A 58PHE A 28GLU A 25 | None | 1.11A | 4jslA-4o6xA:undetectable4jslB-4o6xA:1.9 | 4jslA-4o6xA:13.544jslB-4o6xA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbu | ZMAA (Bacillus cereus) |
PF00698(Acyl_transf_1) | 4 | ARG A 9TRP A 428PHE A 431GLU A 429 | None | 1.43A | 4jslA-4qbuA:undetectable4jslB-4qbuA:0.6 | 4jslA-4qbuA:21.534jslB-4qbuA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3v | POLYKETIDE SYNTHASEPKSR (Bacillussubtilis) |
PF14765(PS-DH) | 4 | VAL A 19TRP A 140PHE A 144GLU A 139 | None | 1.03A | 4jslA-4u3vA:undetectable4jslB-4u3vA:undetectable | 4jslA-4u3vA:19.474jslB-4u3vA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cow | PUTATIVEUNCHARACTERIZEDPROTEIN (Caenorhabditisremanei) |
no annotation | 4 | VAL A 409TRP A 407PHE A 404GLU A 410 | None | 1.34A | 4jslA-5cowA:undetectable4jslB-5cowA:1.7 | 4jslA-5cowA:20.904jslB-5cowA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ft6 | CYSTEINE DESULFURASECSDA (Escherichiacoli) |
PF00266(Aminotran_5) | 4 | VAL A 36TRP A 288PHE A 13GLU A 33 | None | 1.49A | 4jslA-5ft6A:undetectable4jslB-5ft6A:undetectable | 4jslA-5ft6A:21.574jslB-5ft6A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 4 | VAL A 341TRP A 323TRP A 347PHE A 290 | None | 1.10A | 4jslA-5jseA:undetectable4jslB-5jseA:undetectable | 4jslA-5jseA:19.314jslB-5jseA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp8 | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
no annotation | 4 | VAL B4019TRP B4065PHE B4109GLU B4033 | None | 1.23A | 4jslA-5lp8B:undetectable4jslB-5lp8B:undetectable | 4jslA-5lp8B:21.314jslB-5lp8B:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | ARG A 225TRP A 414PHE A 411GLU A 413 | None | 1.09A | 4jslA-5m8tA:undetectable4jslB-5m8tA:0.5 | 4jslA-5m8tA:21.754jslB-5m8tA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no8 | BACCELL_00875 (Bacteroidescellulosilyticus) |
no annotation | 4 | VAL A 538ARG A 205TRP A 599PHE A 606 | None | 1.46A | 4jslA-5no8A:undetectable4jslB-5no8A:2.0 | 4jslA-5no8A:21.874jslB-5no8A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyo | THIOL:DISULFIDEINTERCHANGE PROTEIN (Burkholderiapseudomallei) |
no annotation | 4 | VAL A 57TRP A 56PHE A 49GLU A 54 | None | 1.06A | 4jslA-5vyoA:undetectable4jslB-5vyoA:0.4 | 4jslA-5vyoA:9.714jslB-5vyoA:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S5-B,PUTATIVEUNCHARACTERIZEDPROTEIN (Trichomonasvaginalis) |
PF00177(Ribosomal_S7)PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 4 | VAL c 16ARG F 49PHE F 50GLU c 51 | None C 21421 ( 4.4A)NoneNone | 1.03A | 4jslA-5xyic:undetectable4jslB-5xyic:undetectable | 4jslA-5xyic:12.844jslB-5xyic:12.84 |