SIMILAR PATTERNS OF AMINO ACIDS FOR 4JD6_B_TOYB501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1kqj	A/G-SPECIFIC ADENINE GLYCOSYLASE (Escherichia coli)	PF00633 (HHH) PF00730 (HhH-GPD)	5	PHE A 180 SER A 168 VAL A 171 TYR A 149 GLU A 37	None	1.01A	4jd6B-1kqjA: 0.0	4jd6B-1kqjA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5na7	PUTATIVE DIPEPTIDYL-PEPTIDASE III (Bacteroides thetaiotaomicron)	no annotation	5	PHE A 70 ASP A 67 ILE A 68 TRP A 319 TYR A 656	None	1.15A	4jd6B-5na7A: 0.0	4jd6B-5na7A: 21.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5tvj	ENHANCED INTRACELLULAR SURVIVAL PROTEIN (Mycobacterium tuberculosis)	PF13527 (Acetyltransf_9) PF13530 (SCP2_2)	7	PHE A 24 ASP A 26 ILE A 28 TRP A 36 SER A 83 TYR A 126 GLU A 203	7LF A 502 ( 3.9A) 7LF A 502 (-3.5A) 7LF A 502 (-4.1A) 7LF A 502 (-3.9A) 7LF A 502 (-3.5A) COA A 501 (-4.0A) None	0.90A	4jd6B-5tvjA: 61.2	4jd6B-5tvjA: 98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5tvj	ENHANCED INTRACELLULAR SURVIVAL PROTEIN (Mycobacterium tuberculosis)	PF13527 (Acetyltransf_9) PF13530 (SCP2_2)	7	PHE A 24 ASP A 26 ILE A 28 TRP A 36 SER A 83 VAL A 85 GLU A 203	7LF A 502 ( 3.9A) 7LF A 502 (-3.5A) 7LF A 502 (-4.1A) 7LF A 502 (-3.9A) 7LF A 502 (-3.5A) COA A 501 (-3.8A) None	0.59A	4jd6B-5tvjA: 61.2	4jd6B-5tvjA: 98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5tvj	ENHANCED INTRACELLULAR SURVIVAL PROTEIN (Mycobacterium tuberculosis)	PF13527 (Acetyltransf_9) PF13530 (SCP2_2)	7	PHE A 24 ASP A 26 TRP A 36 SER A 83 TYR A 126 GLU A 203 GLU A 401	7LF A 502 ( 3.9A) 7LF A 502 (-3.5A) 7LF A 502 (-3.9A) 7LF A 502 (-3.5A) COA A 501 (-4.0A) None 7LF A 502 (-3.3A)	1.00A	4jd6B-5tvjA: 61.2	4jd6B-5tvjA: 98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5tvj	ENHANCED INTRACELLULAR SURVIVAL PROTEIN (Mycobacterium tuberculosis)	PF13527 (Acetyltransf_9) PF13530 (SCP2_2)	7	PHE A 24 ASP A 26 TRP A 36 SER A 83 VAL A 85 GLU A 203 GLU A 401	7LF A 502 ( 3.9A) 7LF A 502 (-3.5A) 7LF A 502 (-3.9A) 7LF A 502 (-3.5A) COA A 501 (-3.8A) None 7LF A 502 (-3.3A)	0.68A	4jd6B-5tvjA: 61.2	4jd6B-5tvjA: 98.60

[["4JD6_B_TOYB501_1","1kqj","Escherichia coli","A\/G-SPECIFIC ADENINE GLYCOSYLASE","PF00633(HHH);PF00730(HhH-GPD)",5,"PHE A 180;SER A 168;VAL A 171;TYR A 149;GLU A  37","None","1.01A","4jd6B-1kqjA:0.0","4jd6B-1kqjA:20.79"],["4JD6_B_TOYB501_1","5na7","Bacteroides thetaiotaomicron","PUTATIVE DIPEPTIDYL-PEPTIDASE III","no annotation",5,"PHE A  70;ASP A  67;ILE A  68;TRP A 319;TYR A 656","None","1.15A","4jd6B-5na7A:0.0","4jd6B-5na7A:21.57"],["4JD6_B_TOYB501_1","5tvj","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",7,"PHE A  24;ASP A  26;ILE A  28;TRP A  36;SER A  83;TYR A 126;GLU A 203","7LF A 502 ( 3.9A);7LF A 502 (-3.5A);7LF A 502 (-4.1A);7LF A 502 (-3.9A);7LF A 502 (-3.5A);COA A 501 (-4.0A);None","0.90A","4jd6B-5tvjA:61.2","4jd6B-5tvjA:98.60"],["4JD6_B_TOYB501_1","5tvj","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",7,"PHE A  24;ASP A  26;ILE A  28;TRP A  36;SER A  83;VAL A  85;GLU A 203","7LF A 502 ( 3.9A);7LF A 502 (-3.5A);7LF A 502 (-4.1A);7LF A 502 (-3.9A);7LF A 502 (-3.5A);COA A 501 (-3.8A);None","0.59A","4jd6B-5tvjA:61.2","4jd6B-5tvjA:98.60"],["4JD6_B_TOYB501_1","5tvj","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",7,"PHE A  24;ASP A  26;TRP A  36;SER A  83;TYR A 126;GLU A 203;GLU A 401","7LF A 502 ( 3.9A);7LF A 502 (-3.5A);7LF A 502 (-3.9A);7LF A 502 (-3.5A);COA A 501 (-4.0A);None;7LF A 502 (-3.3A)","1.00A","4jd6B-5tvjA:61.2","4jd6B-5tvjA:98.60"],["4JD6_B_TOYB501_1","5tvj","Mycobacterium tuberculosis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","PF13527(Acetyltransf_9);PF13530(SCP2_2)",7,"PHE A  24;ASP A  26;TRP A  36;SER A  83;VAL A  85;GLU A 203;GLU A 401","7LF A 502 ( 3.9A);7LF A 502 (-3.5A);7LF A 502 (-3.9A);7LF A 502 (-3.5A);COA A 501 (-3.8A);None;7LF A 502 (-3.3A)","0.68A","4jd6B-5tvjA:61.2","4jd6B-5tvjA:98.60"]]