SIMILAR PATTERNS OF AMINO ACIDS FOR 4J4V_C_SVRC301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 4 | GLY A 374ASN A 338PHE A 200ILE A 372 | NoneADP A 421 (-3.3A)NoneNone | 1.00A | 4j4vC-13pkA:0.0 | 4j4vC-13pkA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 4 | GLY A 376ARG A 41PRO A 340PHE A 344 | ADP A 421 (-4.0A)NoneADP A 421 (-4.3A)None | 0.87A | 4j4vC-13pkA:0.0 | 4j4vC-13pkA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 4 | GLY A 365ASN A 258PHE A 321ILE A 362 | None | 0.98A | 4j4vC-1cs1A:0.0 | 4j4vC-1cs1A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2f | MALY PROTEIN (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | ARG A 253PRO A 216PHE A 77ILE A 85 | None | 1.01A | 4j4vC-1d2fA:0.1 | 4j4vC-1d2fA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 4 | GLY A 546ARG A 131PRO A 173ILE A 211 | None | 0.97A | 4j4vC-1e1cA:0.0 | 4j4vC-1e1cA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htp | H-PROTEIN (Pisum sativum) |
PF01597(GCV_H) | 4 | GLY A 26PRO A 71PHE A 56ILE A 101 | None | 0.98A | 4j4vC-1htpA:undetectable | 4j4vC-1htpA:16.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ibj | CYSTATHIONINEBETA-LYASE (Arabidopsisthaliana) |
PF01053(Cys_Met_Meta_PP) | 4 | GLY A 444ASN A 338PHE A 400ILE A 441 | None | 0.99A | 4j4vC-1ibjA:0.0 | 4j4vC-1ibjA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ig0 | THIAMINPYROPHOSPHOKINASE (Saccharomycescerevisiae) |
PF04263(TPK_catalytic)PF04265(TPK_B1_binding) | 4 | GLY A 158ASN A 156PHE A 143ILE A 147 | None | 0.97A | 4j4vC-1ig0A:undetectable | 4j4vC-1ig0A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd2 | HEMATOPOIETICPROSTAGLANDIN DSYNTHASE (Rattusnorvegicus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ASN 1 3LYS 1 1PHE 1 22ILE 1 27 | None | 0.97A | 4j4vC-1pd21:undetectable | 4j4vC-1pd21:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poi | GLUTACONATE COENZYMEA-TRANSFERASE (Acidaminococcusfermentans) |
PF01144(CoA_trans) | 4 | GLY B 169ASN B 116MET B 207ILE B 149 | None | 0.83A | 4j4vC-1poiB:undetectable | 4j4vC-1poiB:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvd | PYRUVATEDECARBOXYLASE (Saccharomycescerevisiae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLY A 84ASN A 83PRO A 162ILE A 132 | None | 0.91A | 4j4vC-1pvdA:undetectable | 4j4vC-1pvdA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 4 | GLY A 112ASN A 113PRO A 285ILE A 104 | None | 0.98A | 4j4vC-1qleA:0.2 | 4j4vC-1qleA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpg | 3-PHOSPHOGLYCERATEKINASE (Saccharomycescerevisiae) |
PF00162(PGK) | 4 | GLY A 370ASN A 334PHE A 194ILE A 367 | MAP A 450 (-3.5A)MAP A 450 (-3.3A)NoneNone | 1.00A | 4j4vC-1qpgA:undetectable | 4j4vC-1qpgA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu4 | ORNITHINEDECARBOXYLASE (Trypanosomabrucei) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | GLY A 324ASN A 327MET A 386ILE A 366 | None | 0.98A | 4j4vC-1qu4A:undetectable | 4j4vC-1qu4A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s0u | TRANSLATIONINITIATION FACTOR 2GAMMA SUBUNIT (Methanocaldococcusjannaschii) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 4 | GLY A 136ARG A 110MET A 42ILE A 168 | None | 1.01A | 4j4vC-1s0uA:undetectable | 4j4vC-1s0uA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s5k | AMINOGLYCOSIDE6'-N-ACETYLTRANSFERASE (Salmonellaenterica) |
PF00583(Acetyltransf_1) | 4 | GLY A 104ASN A 106LYS A 107PHE A 46 | None | 0.93A | 4j4vC-1s5kA:undetectable | 4j4vC-1s5kA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sei | RIBOSOMAL PROTEIN S8 (Geobacillusstearothermophilus) |
PF00410(Ribosomal_S8) | 4 | GLY A 98ASN A 97PHE A 44ILE A 101 | None | 0.86A | 4j4vC-1seiA:undetectable | 4j4vC-1seiA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 4 | GLY A 97ARG A 341PHE A 355ILE A 353 | NoneNoneHEM A1883 ( 4.4A)None | 0.89A | 4j4vC-1sy7A:undetectable | 4j4vC-1sy7A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1th7 | SMALL NUCLEARRIBOPROTEIN PROTEIN (Sulfolobussolfataricus) |
PF01423(LSM) | 4 | GLY A 69ASN A 44MET A 3ILE A 75 | None | 0.92A | 4j4vC-1th7A:undetectable | 4j4vC-1th7A:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umb | 2-OXO ACIDDEHYDROGENASE ALPHASUBUNIT (Thermusthermophilus) |
PF00676(E1_dh) | 4 | GLY A 27ARG A 299PHE A 8ILE A 16 | None | 0.98A | 4j4vC-1umbA:undetectable | 4j4vC-1umbA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uz4 | MAN5A (Cellvibriomixtus) |
PF00150(Cellulase) | 4 | GLY A 380ASN A 379ARG A 335ILE A 419 | None | 0.97A | 4j4vC-1uz4A:undetectable | 4j4vC-1uz4A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlc | 3-ISOPROPYLMALATEDEHYDROGENASE (Thermotogamaritima) |
PF00180(Iso_dh) | 4 | GLY A 257ARG A 327PRO A 272ILE A 11 | None | 0.87A | 4j4vC-1vlcA:undetectable | 4j4vC-1vlcA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | GLY A 136ASN A 363PHE A 160ILE A 132 | None FE A 429 ( 4.3A)NoneNone | 0.98A | 4j4vC-1xzwA:undetectable | 4j4vC-1xzwA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bx7 | DIHYDROOROTATEDEHYDROGENASE (Lactococcuslactis) |
PF01180(DHO_dh) | 4 | GLY A 94MET A 16PHE A 97ILE A 123 | None | 1.01A | 4j4vC-2bx7A:undetectable | 4j4vC-2bx7A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dgo | CYTOTOXICGRANULE-ASSOCIATEDRNA BINDING PROTEIN1 (Mus musculus) |
PF00076(RRM_1) | 4 | GLY A 83MET A 139PHE A 98ILE A 94 | None | 1.00A | 4j4vC-2dgoA:undetectable | 4j4vC-2dgoA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dh7 | NUCLEOLYSIN TIAR (Homo sapiens) |
PF00076(RRM_1) | 4 | GLY A 102MET A 158PHE A 117ILE A 113 | None | 0.88A | 4j4vC-2dh7A:undetectable | 4j4vC-2dh7A:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gq3 | MALATE SYNTHASE G (Mycobacteriumtuberculosis) |
PF01274(Malate_synthase) | 4 | GLY A 293ASN A 295LYS A 296PHE A 19 | None | 0.92A | 4j4vC-2gq3A:undetectable | 4j4vC-2gq3A:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2grv | LPQW (Mycolicibacteriumsmegmatis) |
PF00496(SBP_bac_5) | 4 | GLY A 247ASN A 246PRO A 574ILE A 267 | None | 0.95A | 4j4vC-2grvA:undetectable | 4j4vC-2grvA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mjn | NUCLEOLYSIN TIA-1ISOFORM P40 (Homo sapiens) |
PF00076(RRM_1) | 4 | GLY A 100MET A 156PHE A 115ILE A 111 | None | 0.77A | 4j4vC-2mjnA:undetectable | 4j4vC-2mjnA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2obv | S-ADENOSYLMETHIONINESYNTHETASE ISOFORMTYPE-1 (Homo sapiens) |
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C) | 4 | GLY A 63ASN A 105PRO A 255ILE A 87 | None | 1.01A | 4j4vC-2obvA:0.6 | 4j4vC-2obvA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pnw | MEMBRANE-BOUND LYTICMUREINTRANSGLYCOSYLASE (Agrobacteriumfabrum) |
PF03562(MltA)PF06725(3D) | 4 | GLY A 209ARG A 121PHE A 137ILE A 128 | None | 0.69A | 4j4vC-2pnwA:undetectable | 4j4vC-2pnwA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qpm | CYTOKININDEHYDROGENASE 1 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | GLY A 62ASN A 63ARG A 392PHE A 112 | NoneNAG A1601 (-1.8A)NoneNone | 0.95A | 4j4vC-2qpmA:undetectable | 4j4vC-2qpmA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | PRO A 99MET A 140PHE A 79ILE A 76 | None | 0.97A | 4j4vC-2wzsA:undetectable | 4j4vC-2wzsA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y35 | LD22664P (Drosophilamelanogaster) |
PF03159(XRN_N) | 4 | GLY A 230ASN A 232ARG A 235PRO A 46 | None | 0.83A | 4j4vC-2y35A:undetectable | 4j4vC-2y35A:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yia | RNA-DIRECTED RNAPOLYMERASE (Infectiouspancreaticnecrosis virus) |
PF04197(Birna_RdRp) | 4 | GLY A 620PRO A 576PHE A 361ILE A 683 | None | 0.98A | 4j4vC-2yiaA:undetectable | 4j4vC-2yiaA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwk | INTIMIN (Escherichiacoli) |
PF02368(Big_2)PF07979(Intimin_C) | 4 | GLY A 70ASN A 69PRO A 93ILE A 90 | None | 0.93A | 4j4vC-2zwkA:undetectable | 4j4vC-2zwkA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4y | PROBABLEF420-DEPENDENTGLUCOSE-6-PHOSPHATEDEHYDROGENASE FGD1 (Mycobacteriumtuberculosis) |
PF00296(Bac_luciferase) | 4 | GLY A 177ARG A 283MET A 208PHE A 192 | F42 A 338 (-3.4A)FLC A 337 (-2.8A)NoneNone | 0.99A | 4j4vC-3b4yA:undetectable | 4j4vC-3b4yA:24.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9t | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNALPROTEIN (Methylobacillusflagellatus) |
PF03069(FmdA_AmdA) | 4 | GLY A 340ARG A 187PHE A 364ILE A 105 | None | 1.00A | 4j4vC-3b9tA:undetectable | 4j4vC-3b9tA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Homo sapiens) |
PF16113(ECH_2) | 4 | GLY A 192MET A 167PHE A 165ILE A 212 | None | 0.80A | 4j4vC-3bptA:undetectable | 4j4vC-3bptA:24.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fca | CYSTEINE SYNTHASE (Thermusthermophilus) |
PF00291(PALP) | 4 | GLY A 31ASN A 29MET A 64ILE A 71 | None | 0.98A | 4j4vC-3fcaA:undetectable | 4j4vC-3fcaA:25.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il0 | XAA-PROAMINOPEPTIDASEAMINOPEPTIDASE P (Streptococcusthermophilus) |
PF01321(Creatinase_N) | 4 | GLY A 92MET A 121PHE A 8ILE A 43 | None | 0.92A | 4j4vC-3il0A:undetectable | 4j4vC-3il0A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j0o | RIBOSOMAL PROTEINS15 (Oryctolaguscuniculus) |
PF00203(Ribosomal_S19) | 4 | GLY S 96LYS S 113ARG S 14PRO S 78 | None | 0.75A | 4j4vC-3j0oS:undetectable | 4j4vC-3j0oS:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kez | PUTATIVE SUGARBINDING PROTEIN (Bacteroidesvulgatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | GLY A 294ASN A 297PRO A 288ILE A 353 | None | 0.97A | 4j4vC-3kezA:undetectable | 4j4vC-3kezA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ki6 | CHOLIX TOXIN (Vibrio cholerae) |
PF09009(Exotox-A_cataly) | 4 | GLY A 458PRO A 624PHE A 541ILE A 533 | None | 0.65A | 4j4vC-3ki6A:undetectable | 4j4vC-3ki6A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l0d | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bartonellahenselae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | GLY A 319ASN A 322ARG A 26ILE A 273 | None | 0.97A | 4j4vC-3l0dA:undetectable | 4j4vC-3l0dA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mhu | DIHYDROOROTATEDEHYDROGENASE (Leishmaniamajor) |
PF01180(DHO_dh) | 4 | GLY A 272ARG A 224PHE A 283ILE A 282 | FMN A 313 (-3.3A)NoneNoneNone | 0.93A | 4j4vC-3mhuA:undetectable | 4j4vC-3mhuA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ni8 | PFC0360W PROTEIN (Plasmodiumfalciparum) |
PF08327(AHSA1) | 4 | GLY A 139ASN A 143PHE A 89ILE A 70 | None | 0.79A | 4j4vC-3ni8A:undetectable | 4j4vC-3ni8A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nmr | CUGBP ELAV-LIKEFAMILY MEMBER 1 (Homo sapiens) |
PF00076(RRM_1) | 4 | GLY A 113MET A 168PHE A 128ILE A 124 | G B 3 ( 3.2A)NoneNoneNone | 0.85A | 4j4vC-3nmrA:undetectable | 4j4vC-3nmrA:20.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ouo | NUCLEOPROTEIN (Rift Valleyfeverphlebovirus) |
PF05733(Tenui_N) | 5 | GLY A 65ASN A 66PRO A 127PHE A 176ILE A 180 | None | 0.88A | 4j4vC-3ouoA:20.1 | 4j4vC-3ouoA:38.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p09 | BETA-LACTAMASE (Francisellatularensis) |
PF13354(Beta-lactamase2) | 4 | GLY A 135ASN A 139PHE A 81ILE A 71 | None | 0.94A | 4j4vC-3p09A:undetectable | 4j4vC-3p09A:24.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9o | EXOTOXIN A (Vibrio cholerae) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 4 | GLY A 458PRO A 624PHE A 541ILE A 533 | None | 0.80A | 4j4vC-3q9oA:undetectable | 4j4vC-3q9oA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qc2 | GLYCOSYL HYDROLASE (Bacteroidesovatus) |
PF04041(Glyco_hydro_130) | 4 | GLY A 370ASN A 48PRO A 78ILE A 51 | None | 0.95A | 4j4vC-3qc2A:undetectable | 4j4vC-3qc2A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rj9 | ALCOHOLDEHYDROGENASE (Scaptodrosophilalebanonensis) |
PF00106(adh_short) | 4 | GLY A 91ASN A 90PHE A 221ILE A 179 | NAD A 850 (-4.7A)NoneNoneNone | 0.84A | 4j4vC-3rj9A:undetectable | 4j4vC-3rj9A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s29 | SUCROSE SYNTHASE 1 (Arabidopsisthaliana) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 4 | GLY A 158ASN A 522PRO A 149ILE A 155 | None | 0.96A | 4j4vC-3s29A:undetectable | 4j4vC-3s29A:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tp2 | PRE-MRNA-SPLICINGFACTOR CWC2 (Saccharomycescerevisiae) |
PF00076(RRM_1)PF16131(Torus) | 4 | GLY A 140MET A 199PHE A 164ILE A 160 | None | 0.89A | 4j4vC-3tp2A:undetectable | 4j4vC-3tp2A:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v1v | 2-METHYLISOBORNEOLSYNTHASE (Streptomycescoelicolor) |
no annotation | 4 | GLY A 338ASN A 339PRO A 309ILE A 334 | None | 1.02A | 4j4vC-3v1vA:undetectable | 4j4vC-3v1vA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsm | OCCLUSION-DERIVEDVIRUS ENVELOPEPROTEIN E66 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF04850(Baculo_E66) | 4 | GLY A 441ASN A 440PRO A 405ILE A 402 | None | 0.74A | 4j4vC-3vsmA:undetectable | 4j4vC-3vsmA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w21 | PUTATIVEUNCHARACTERIZEDPROTEIN (Burkholderiaambifaria) |
no annotation | 4 | GLY A 179ARG A 199PHE A 272ILE A 263 | AKG A 302 ( 4.8A)NoneNoneNone | 0.97A | 4j4vC-3w21A:undetectable | 4j4vC-3w21A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdn | GLYCINE CLEAVAGESYSTEM H PROTEIN,MITOCHONDRIAL (Bos taurus) |
PF01597(GCV_H) | 4 | GLY A 22PRO A 67PHE A 52ILE A 97 | None | 0.86A | 4j4vC-3wdnA:undetectable | 4j4vC-3wdnA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a8x | RNA-BINDING PROTEINWITH SERINE-RICHDOMAIN 1 (Homo sapiens) |
PF00076(RRM_1) | 4 | GLY A 166MET A 223PHE A 181ILE A 177 | None | 0.88A | 4j4vC-4a8xA:undetectable | 4j4vC-4a8xA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 4 | GLY A 188ASN A 192ARG A 196ILE A 35 | None | 1.01A | 4j4vC-4dr0A:1.0 | 4j4vC-4dr0A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4j | ARGININE DEIMINASE (Mycoplasmapenetrans) |
PF02274(Amidinotransf) | 4 | GLY A 258ASN A 216MET A 209ILE A 271 | None | 0.96A | 4j4vC-4e4jA:undetectable | 4j4vC-4e4jA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ex4 | MALATE SYNTHASE G (Mycobacteriumleprae) |
PF01274(Malate_synthase) | 4 | GLY A 294ASN A 296LYS A 297PHE A 19 | None | 0.92A | 4j4vC-4ex4A:undetectable | 4j4vC-4ex4A:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eys | MCCC FAMILY PROTEIN (Streptococcuspneumoniae) |
PF02016(Peptidase_S66) | 4 | GLY A 27PRO A 38PHE A 40ILE A 7 | None | 0.87A | 4j4vC-4eysA:undetectable | 4j4vC-4eysA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixo | NIFS-LIKE PROTEIN (Rickettsiaafricae) |
PF00266(Aminotran_5) | 4 | GLY A 241ARG A 48PHE A 175ILE A 192 | None | 0.97A | 4j4vC-4ixoA:undetectable | 4j4vC-4ixoA:18.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j4s | NUCLEOCAPSID PROTEIN (SFTSphlebovirus) |
PF05733(Tenui_N) | 5 | ASN A 66PRO A 127MET A 147PHE A 177ILE A 181 | None | 0.92A | 4j4vC-4j4sA:36.5 | 4j4vC-4j4sA:98.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j4s | NUCLEOCAPSID PROTEIN (SFTSphlebovirus) |
PF05733(Tenui_N) | 5 | GLY A 65ASN A 66ARG A 95PRO A 127PHE A 177 | None | 0.71A | 4j4vC-4j4sA:36.5 | 4j4vC-4j4sA:98.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j4s | NUCLEOCAPSID PROTEIN (SFTSphlebovirus) |
PF05733(Tenui_N) | 5 | GLY A 65ASN A 66PRO A 127MET A 147PHE A 177 | None | 0.78A | 4j4vC-4j4sA:36.5 | 4j4vC-4j4sA:98.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j4w | NUCLEOCAPSID (Punta Torophlebovirus) |
PF05733(Tenui_N) | 6 | GLY A 64ASN A 65LYS A 66PRO A 126PHE A 175ILE A 179 | None | 0.89A | 4j4vC-4j4wA:31.8 | 4j4vC-4j4wA:37.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j4x | NP PROTEIN (Sandfly feverNaplesphlebovirus) |
PF05733(Tenui_N) | 6 | GLY A 70ASN A 71LYS A 72PRO A 132PHE A 182ILE A 186 | None | 0.93A | 4j4vC-4j4xA:31.3 | 4j4vC-4j4xA:36.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqt | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesthetaiotaomicron) |
PF06439(DUF1080) | 4 | GLY A 119ARG A 115PHE A 78ILE A 110 | None | 0.90A | 4j4vC-4jqtA:undetectable | 4j4vC-4jqtA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k9q | BENZOYLFORMATEDECARBOXYLASE (Polynucleobacternecessarius) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ASN A 199ARG A 329PRO A 287ILE A 267 | None | 0.97A | 4j4vC-4k9qA:undetectable | 4j4vC-4k9qA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpu | ELECTRON TRANSFERFLAVOPROTEIN ALPHASUBUNITELECTRON TRANSFERFLAVOPROTEINALPHA/BETA-SUBUNIT (Acidaminococcusfermentans) |
PF00766(ETF_alpha)PF01012(ETF) | 4 | GLY A 151ASN A 152ARG B 27ILE B 121 | None | 0.87A | 4j4vC-4kpuA:undetectable | 4j4vC-4kpuA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lr2 | BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4 (Homo sapiens) |
PF01663(Phosphodiest) | 4 | ASN A 282LYS A 283PRO A 273ILE A 275 | None | 0.90A | 4j4vC-4lr2A:undetectable | 4j4vC-4lr2A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qhr | ALANINE RACEMASE (Acinetobacterbaumannii) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | GLY A 274PRO A 351PHE A 236ILE A 271 | None | 0.92A | 4j4vC-4qhrA:undetectable | 4j4vC-4qhrA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wwu | MRNA TRANSPORTREGULATOR MTR2 (Saccharomycescerevisiae) |
PF10429(Mtr2) | 4 | GLY C 164ASN C 163PHE C 22ILE C 157 | None | 0.90A | 4j4vC-4wwuC:undetectable | 4j4vC-4wwuC:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzr | POLYKETIDEBIOSYNTHESISCYTOCHROME P450 PKSS (Bacillussubtilis) |
PF00067(p450) | 4 | GLY A 318ASN A 321ARG A 337PRO A 17 | GLY A 318 ( 0.0A)ASN A 321 ( 0.6A)ARG A 337 ( 0.6A)PRO A 17 ( 1.0A) | 0.94A | 4j4vC-4yzrA:2.5 | 4j4vC-4yzrA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztb | PROTEASE NSP2 (Chikungunyavirus) |
PF01707(Peptidase_C9) | 4 | ARG A 136MET A 292PHE A 294ILE A 268 | None | 0.95A | 4j4vC-4ztbA:undetectable | 4j4vC-4ztbA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyj | DNMZ (Streptomycespeucetius) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | GLY A 99PRO A 54MET A 175PHE A 58 | None | 1.00A | 4j4vC-4zyjA:undetectable | 4j4vC-4zyjA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7v | PUTATIVE GLYCOSIDASEPH117-RELATED (Bacteroidesthetaiotaomicron) |
PF04041(Glyco_hydro_130) | 4 | GLY B 367ASN B 45PRO B 75ILE B 48 | NoneNoneNoneSO4 B1388 (-4.8A) | 0.94A | 4j4vC-5a7vB:undetectable | 4j4vC-5a7vB:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aeb | LRA-12 (unculturedbacterium BLR12) |
PF00753(Lactamase_B) | 4 | GLY A 50ASN A 51PRO A 281ILE A 48 | None | 0.99A | 4j4vC-5aebA:undetectable | 4j4vC-5aebA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA, K-ATPASE ALPHASUBUNIT (Squalusacanthias) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 4 | GLY A 379ASN A 384ARG A 385ILE A 736 | MG A2002 ( 4.4A)NoneNoneNone | 0.98A | 4j4vC-5aw4A:undetectable | 4j4vC-5aw4A:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE BASICPROTEIN 2RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Cvirus) |
PF00602(Flu_PB1)PF00604(Flu_PB2) | 4 | GLY C 745PRO B 704PHE B 692ILE B 710 | None | 0.97A | 4j4vC-5d9aC:undetectable | 4j4vC-5d9aC:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eu0 | BARTONELLA EFFECTORPROTEIN (BEP)SUBSTRATE OF VIRBT4SS (Bartonellarochalimae) |
PF02661(Fic) | 4 | GLY A 133ASN A 136ARG A 139PRO A 171 | NoneNoneSO4 A 302 (-2.7A)None | 0.99A | 4j4vC-5eu0A:1.2 | 4j4vC-5eu0A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | GLY B 129ASN B 111ARG B 156MET B 61 | None | 0.92A | 4j4vC-5fq6B:undetectable | 4j4vC-5fq6B:13.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7j | ELONGATION FACTOR 2 (Pyrococcushorikoshii) |
no annotation | 4 | GLY A 206MET A 167PHE A 226ILE A 229 | None | 0.92A | 4j4vC-5h7jA:undetectable | 4j4vC-5h7jA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h9f | CRISPR SYSTEMCASCADE SUBUNIT CASA (Escherichiacoli) |
PF09481(CRISPR_Cse1) | 4 | GLY A 227ASN A 207LYS A 205PRO A 278 | None | 1.02A | 4j4vC-5h9fA:undetectable | 4j4vC-5h9fA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hc4 | LIPOLYTIC ENZYME (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | GLY A 198LYS A 202PRO A 265PHE A 296 | None | 1.00A | 4j4vC-5hc4A:undetectable | 4j4vC-5hc4A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw7 | RIBOSOME BIOGENESISPROTEINTSR1,RIBOSOMEBIOGENESIS PROTEINTSR1 (Saccharomycescerevisiae) |
PF04950(RIBIOP_C)PF08142(AARP2CN) | 4 | ASN A 786ARG A 622PHE A 301ILE A 295 | None | 0.92A | 4j4vC-5iw7A:undetectable | 4j4vC-5iw7A:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE ALPHASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | GLY b 233ASN b 230PRO b 290PHE b 292 | None | 0.92A | 4j4vC-5l9wb:undetectable | 4j4vC-5l9wb:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lac | 3CL PROTEASE (Alphamesonivirus1) |
PF17222(Peptidase_C107) | 4 | GLY A 114ASN A 230PRO A 160ILE A 8 | None | 0.92A | 4j4vC-5lacA:undetectable | 4j4vC-5lacA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m11 | IMMUNOREACTIVE 84KDANTIGEN PG93 (Porphyromonasgingivalis) |
no annotation | 4 | PRO A 243MET A 211PHE A 226ILE A 224 | None | 1.01A | 4j4vC-5m11A:undetectable | 4j4vC-5m11A:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olj | DIPEPTIDYL PEPTIDASEIV (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | ARG A 544MET A 508PHE A 610ILE A 570 | None | 1.00A | 4j4vC-5oljA:undetectable | 4j4vC-5oljA:14.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wzk | PUMILIO HOMOLOG 23 (Arabidopsisthaliana) |
no annotation | 4 | GLY A 118ASN A 119PHE A 103ILE A 99 | None | 0.93A | 4j4vC-5wzkA:undetectable | 4j4vC-5wzkA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xt3 | PHOSPHODIESTERASEACTING ON CYCLICDINUCLEOTIDES (Staphylococcusaureus) |
no annotation | 4 | GLY A 352MET A 385PHE A 398ILE A 370 | None | 0.95A | 4j4vC-5xt3A:undetectable | 4j4vC-5xt3A:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ybw | ASPARTATE RACEMASE (Scapharcabroughtonii) |
no annotation | 4 | GLY A 90ASN A 91PRO A 112ILE A 247 | NoneLLP A 63 ( 3.7A)NoneNone | 0.95A | 4j4vC-5ybwA:undetectable | 4j4vC-5ybwA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT F (Flavobacteriumjohnsoniae) |
no annotation | 4 | PRO F 362MET F 410PHE F 406ILE F 420 | None | 0.83A | 4j4vC-6btmF:undetectable | 4j4vC-6btmF:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6k | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Acinetobacterbaumannii) |
no annotation | 4 | GLY A 438ASN A 437PHE A 384ILE A 433 | None | 1.00A | 4j4vC-6d6kA:undetectable | 4j4vC-6d6kA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6exs | PEPTIDE ABCTRANSPORTER PERMEASE (Staphylococcushominis) |
no annotation | 4 | GLY A 313ASN A 318PHE A 472ILE A 390 | C3H A 514 (-3.3A)NoneNoneNone | 0.91A | 4j4vC-6exsA:undetectable | 4j4vC-6exsA:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 4 | GLY A 136ASN A 140ARG A 145PHE A 305 | None | 0.75A | 4j4vC-6gbnA:undetectable | 4j4vC-6gbnA:undetectable |