SIMILAR PATTERNS OF AMINO ACIDS FOR 4J26_B_ESTB600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 5 | MET A 60LEU A 131LEU A 114ILE A 183LEU A 20 | None | 1.25A | 4j26B-13pkA:undetectable | 4j26B-13pkA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dl2 | CLASS IALPHA-1,2-MANNOSIDASE (Saccharomycescerevisiae) |
PF01532(Glyco_hydro_47) | 5 | MET A 301MET A 304LEU A 308ILE A 381LEU A 345 | None | 1.19A | 4j26B-1dl2A:undetectable | 4j26B-1dl2A:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | LEU A 403LEU A 401ILE A 387ILE A 396LEU A 309 | None | 1.13A | 4j26B-1g8kA:undetectable | 4j26B-1g8kA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfe | PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(LARGER SUBUNIT)) (Desulfovibriovulgaris) |
PF02906(Fe_hyd_lg_C)PF13237(Fer4_10) | 5 | MET L 219LEU L 210ILE L 103HIS L 141LEU L 285 | None | 1.20A | 4j26B-1hfeL:undetectable | 4j26B-1hfeL:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i51 | CASPASE-7 SUBUNITP20 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 183ILE A 150LEU A 142 | None | 1.05A | 4j26B-1i51A:undetectable | 4j26B-1i51A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k86 | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 183ILE A 150LEU A 142 | None | 1.14A | 4j26B-1k86A:undetectable | 4j26B-1k86A:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mw9 | DNA TOPOISOMERASE I (Escherichiacoli) |
PF01131(Topoisom_bac)PF01751(Toprim) | 5 | GLU X 547ARG X 168ILE X 504ILE X 501LEU X 203 | None | 1.26A | 4j26B-1mw9X:1.3 | 4j26B-1mw9X:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nkl | NK-LYSIN (Sus scrofa) |
PF05184(SapB_1) | 5 | MET A 49GLU A 24LEU A 61ILE A 69LEU A 14 | None | 1.04A | 4j26B-1nklA:undetectable | 4j26B-1nklA:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1or4 | HEME-BASEDAEROTACTICTRANSDUCER HEMAT (Bacillussubtilis) |
PF11563(Protoglobin) | 5 | LEU A 96LEU A 73ILE A 126ILE A 82HIS A 86 | CYN A 181 ( 4.5A)HEM A 180 ( 4.7A)HEM A 180 (-4.5A)HEM A 180 (-3.5A)HEM A 180 (-4.7A) | 1.29A | 4j26B-1or4A:1.0 | 4j26B-1or4A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p3w | CYSTEINE DESULFURASE (Escherichiacoli) |
no annotation | 5 | LEU B 147LEU B 199MET B 200ILE B 166ILE B 163 | None | 1.24A | 4j26B-1p3wB:undetectable | 4j26B-1p3wB:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p43 | ENOLASE 1 (Saccharomycescerevisiae) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 342LEU A 343ILE A 383ILE A 395LEU A 390 | None2PG A 441 (-4.7A)NoneNoneNone | 1.20A | 4j26B-1p43A:undetectable | 4j26B-1p43A:20.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | MET A 342LEU A 349GLU A 353LEU A 391ARG A 394 | NoneEST A 1 ( 4.8A)EST A 1 (-2.8A)EST A 1 ( 3.9A)EST A 1 (-3.7A) | 1.31A | 4j26B-1pcgA:32.9 | 4j26B-1pcgA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 10 | MET A 343LEU A 349GLU A 353LEU A 387MET A 388LEU A 391ARG A 394ILE A 424HIS A 524LEU A 525 | EST A 1 ( 4.0A)EST A 1 ( 4.8A)EST A 1 (-2.8A)EST A 1 (-4.0A)NoneEST A 1 ( 3.9A)EST A 1 (-3.7A)EST A 1 ( 4.5A)EST A 1 (-3.8A)EST A 1 (-3.6A) | 0.37A | 4j26B-1pcgA:32.9 | 4j26B-1pcgA:59.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdz | ENOLASE (Homarusgammarus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 341LEU A 342ILE A 382ILE A 394LEU A 389 | None | 1.19A | 4j26B-1pdzA:undetectable | 4j26B-1pdzA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pw5 | NAGD PROTEIN,PUTATIVE (Thermotogamaritima) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | LEU A 125LEU A 119ILE A 109ILE A 90LEU A 98 | None | 1.22A | 4j26B-1pw5A:undetectable | 4j26B-1pw5A:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ub3 | ALDOLASE PROTEIN (Thermusthermophilus) |
PF01791(DeoC) | 5 | LEU A 105GLU A 108LEU A 94ILE A 135LEU A 150 | None | 1.30A | 4j26B-1ub3A:undetectable | 4j26B-1ub3A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uw0 | DNA LIGASE III (Homo sapiens) |
PF00645(zf-PARP) | 5 | LEU A 76ILE A 53ILE A 90HIS A 93LEU A 97 | None | 1.19A | 4j26B-1uw0A:undetectable | 4j26B-1uw0A:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl2 | ARGININOSUCCINATESYNTHASE (Thermotogamaritima) |
PF00764(Arginosuc_synth) | 5 | MET A 184LEU A 76ILE A 91ILE A 319LEU A 86 | None | 1.27A | 4j26B-1vl2A:undetectable | 4j26B-1vl2A:22.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 327GLU A 331MET A 362LEU A 365ARG A 372HIS A 494 | None | 0.61A | 4j26B-1xb7A:28.3 | 4j26B-1xb7A:34.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z1w | TRICORN PROTEASEINTERACTING FACTORF3 (Thermoplasmaacidophilum) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | MET A 674LEU A 668LEU A 662ILE A 656LEU A 640 | None | 1.25A | 4j26B-1z1wA:undetectable | 4j26B-1z1wA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq9 | PROBABLEDIMETHYLADENOSINETRANSFERASE (Homo sapiens) |
PF00398(RrnaAD) | 5 | GLU A 222LEU A 226ILE A 295ILE A 177LEU A 182 | None | 1.29A | 4j26B-1zq9A:undetectable | 4j26B-1zq9A:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akz | GAMMA ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 339LEU A 340ILE A 380ILE A 392LEU A 387 | None | 1.16A | 4j26B-2akzA:undetectable | 4j26B-2akzA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ga8 | HYPOTHETICAL 39.9KDA PROTEIN (Saccharomycescerevisiae) |
PF07728(AAA_5) | 5 | LEU A 290LEU A 270LEU A 271ILE A 350ILE A 295 | None | 1.30A | 4j26B-2ga8A:undetectable | 4j26B-2ga8A:22.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 271GLU A 275MET A 306LEU A 309ARG A 316HIS A 434 | OHT A 500 ( 4.4A)OHT A 500 (-2.6A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)OHT A 500 (-3.8A)OHT A 500 ( 4.7A) | 0.51A | 4j26B-2gpvA:27.3 | 4j26B-2gpvA:37.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j5g | ALR4455 PROTEIN (Nostoc sp. PCC7120) |
PF00378(ECH_1) | 5 | LEU D 103LEU D 104ARG D 221ILE D 157ILE D 236 | None | 1.08A | 4j26B-2j5gD:undetectable | 4j26B-2j5gD:22.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 10 | MET A 343LEU A 349GLU A 353LEU A 387MET A 388LEU A 391ARG A 394ILE A 424HIS A 524LEU A 525 | EST A 596 (-4.8A)EST A 596 ( 4.1A)EST A 596 (-2.7A)EST A 596 ( 4.2A)NoneEST A 596 ( 4.6A)EST A 596 (-4.0A)EST A 596 ( 4.7A)EST A 596 (-4.2A)EST A 596 (-3.6A) | 0.44A | 4j26B-2ocfA:33.9 | 4j26B-2ocfA:57.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omv | INTERNALIN-A (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | LEU A 126ARG A 168ILE A 132ILE A 135LEU A 116 | None | 1.20A | 4j26B-2omvA:undetectable | 4j26B-2omvA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oze | ORF DELTA' (Streptococcuspyogenes) |
PF13614(AAA_31) | 5 | LEU A 60LEU A 66ILE A 39ILE A 159LEU A 53 | None | 1.29A | 4j26B-2ozeA:undetectable | 4j26B-2ozeA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa6 | ENOLASE (Methanocaldococcusjannaschii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 272LEU A 273ILE A 309ILE A 311LEU A 247 | None | 1.18A | 4j26B-2pa6A:undetectable | 4j26B-2pa6A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa6 | ENOLASE (Methanocaldococcusjannaschii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 336LEU A 337ILE A 377ILE A 389LEU A 384 | None | 1.25A | 4j26B-2pa6A:undetectable | 4j26B-2pa6A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ptz | ENOLASE (Trypanosomabrucei) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 340LEU A 341ILE A 381ILE A 393LEU A 388 | NonePAH A 600 (-4.8A)NoneNoneNone | 1.30A | 4j26B-2ptzA:undetectable | 4j26B-2ptzA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ql7 | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 183ILE A 150LEU A 142 | None | 1.02A | 4j26B-2ql7A:undetectable | 4j26B-2ql7A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzb | UNCHARACTERIZEDPROTEIN YFEY (Escherichiacoli) |
PF06572(DUF1131) | 5 | MET A 95LEU A 55ARG A 83ILE A 107LEU A 64 | None | 1.24A | 4j26B-2qzbA:undetectable | 4j26B-2qzbA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rb9 | HYPE PROTEIN (Escherichiacoli) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 192LEU A 262ILE A 183ILE A 335HIS A 179 | None | 1.29A | 4j26B-2rb9A:undetectable | 4j26B-2rb9A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbe | BIPOLAR KINESINKRP-130 (Drosophilamelanogaster) |
PF00225(Kinesin) | 5 | LEU C 247LEU C 75ILE C 317ILE C 8LEU C 305 | None | 0.94A | 4j26B-2wbeC:undetectable | 4j26B-2wbeC:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsx | BETA-ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 340LEU A 341ILE A 381ILE A 393LEU A 388 | None | 1.18A | 4j26B-2xsxA:undetectable | 4j26B-2xsxA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b97 | ALPHA-ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 339LEU A 340ILE A 380ILE A 392LEU A 387 | None | 1.16A | 4j26B-3b97A:undetectable | 4j26B-3b97A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg2 | DGTPTRIPHOSPHOHYDROLASE (Leeuwenhoekiellablandensis) |
PF01966(HD) | 5 | LEU A 94GLU A 5MET A 2ILE A 329LEU A 245 | None | 1.04A | 4j26B-3bg2A:undetectable | 4j26B-3bg2A:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bh0 | DNAB-LIKEREPLICATIVE HELICASE (Bacillus phageSPP1) |
PF03796(DnaB_C) | 5 | LEU A 354LEU A 199ILE A 333ILE A 336LEU A 319 | None | 1.12A | 4j26B-3bh0A:undetectable | 4j26B-3bh0A:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3csq | MORPHOGENESISPROTEIN 1 (Bacillus virusphi29) |
no annotation | 5 | LEU A 22MET A 42LEU A 39MET A 38ILE A 98 | None | 1.17A | 4j26B-3csqA:undetectable | 4j26B-3csqA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3csz | MORPHOGENESISPROTEIN 1 (Bacillus virusphi29) |
no annotation | 5 | LEU A 22MET A 42LEU A 39MET A 38ILE A 98 | None | 1.21A | 4j26B-3cszA:undetectable | 4j26B-3cszA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | GLU A 894LEU A 776ARG A 505ILE A 878LEU A 932 | None | 1.26A | 4j26B-3dy5A:undetectable | 4j26B-3dy5A:13.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ffh | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Listeriainnocua) |
PF00155(Aminotran_1_2) | 5 | LEU A 189GLU A 191ILE A 240ILE A 241LEU A 93 | None | 1.22A | 4j26B-3ffhA:undetectable | 4j26B-3ffhA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fms | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Thermotogamaritima) |
PF00392(GntR)PF07729(FCD) | 5 | LEU A 193GLU A 90ARG A 86ILE A 114LEU A 107 | NoneNoneACT A 302 (-3.0A)NoneNone | 1.17A | 4j26B-3fmsA:undetectable | 4j26B-3fmsA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5i | PYRIMIDINE-SPECIFICRIBONUCLEOSIDEHYDROLASE RIHA (Escherichiacoli) |
PF01156(IU_nuc_hydro) | 5 | LEU A 21LEU A 28ILE A 33ILE A 61LEU A 56 | None | 1.11A | 4j26B-3g5iA:undetectable | 4j26B-3g5iA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvn | ESTERASE ESTA (Pseudomonasaeruginosa) |
no annotation | 5 | LEU X 561LEU X 186LEU X 230ILE X 182ILE X 142 | None | 1.26A | 4j26B-3kvnX:undetectable | 4j26B-3kvnX:14.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kye | ROADBLOCK/LC7DOMAIN, ROBL_LC7 (Streptomycesavermitilis) |
PF03259(Robl_LC7) | 5 | LEU A 16MET A 17LEU A 20ARG A 23LEU A 128 | None | 1.19A | 4j26B-3kyeA:undetectable | 4j26B-3kyeA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdk | STRINGENT STARVATIONPROTEIN A (Pseudomonasputida) |
PF00043(GST_C)PF13417(GST_N_3) | 5 | LEU A 23GLU A 27LEU A 84ARG A 190ILE A 102 | None | 0.98A | 4j26B-3mdkA:undetectable | 4j26B-3mdkA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3msy | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (marineactinobacteriumPHSC20C1) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | MET A 95LEU A 141ILE A 28ILE A 61LEU A 137 | None | 1.19A | 4j26B-3msyA:undetectable | 4j26B-3msyA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7j | OHCU DECARBOXYLASE (Klebsiellapneumoniae) |
PF09349(OHCU_decarbox) | 5 | GLU A 161LEU A 158ARG A 49HIS A 80LEU A 83 | None | 1.31A | 4j26B-3o7jA:undetectable | 4j26B-3o7jA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otr | ENOLASE (Toxoplasmagondii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 352LEU A 353ILE A 393ILE A 405LEU A 400 | None | 1.15A | 4j26B-3otrA:undetectable | 4j26B-3otrA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oxp | PHOSPHOTRANSFERASEENZYME II, ACOMPONENT (Yersinia pestis) |
PF00359(PTS_EIIA_2) | 5 | LEU A 80MET A 1LEU A 2ILE A 115HIS A 111 | None | 1.31A | 4j26B-3oxpA:undetectable | 4j26B-3oxpA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rwb | PYRIDOXAL4-DEHYDROGENASE (Mesorhizobiumloti) |
PF13561(adh_short_C2) | 5 | LEU A 168LEU A 85ILE A 118ILE A 62LEU A 113 | NoneNoneNoneNAD A 251 (-3.9A)None | 1.22A | 4j26B-3rwbA:undetectable | 4j26B-3rwbA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sxm | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Thermotogamaritima) |
PF07729(FCD) | 5 | LEU A 193GLU A 90ARG A 86ILE A 114LEU A 107 | None | 1.23A | 4j26B-3sxmA:undetectable | 4j26B-3sxmA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7v | METHYLORNITHINESYNTHASE PYLB (Methanosarcinabarkeri) |
PF04055(Radical_SAM) | 5 | LEU A 209GLU A 171MET A 226ILE A 262ILE A 274 | SAM A 992 (-4.8A)SAM A 992 (-2.8A)NoneNoneNone | 1.06A | 4j26B-3t7vA:undetectable | 4j26B-3t7vA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atg | TAF6 (Antonosporalocustae) |
PF07571(TAF6_C) | 5 | LEU A 222LEU A 211ILE A 247ILE A 205LEU A 228 | None | 1.23A | 4j26B-4atgA:undetectable | 4j26B-4atgA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bax | GLUTAMINE SYNTHETASE (Streptomycescoelicolor) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 5 | LEU A 335ARG A 321ILE A 252ILE A 253LEU A 343 | None | 1.21A | 4j26B-4baxA:undetectable | 4j26B-4baxA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bla | MALTOSE-BINDINGPERIPLASMIC PROTEIN,SUPPRESSOR OF FUSEDHOMOLOG (Escherichiacoli;Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C)PF13416(SBP_bac_8) | 5 | MET A 708LEU A 654ILE A 671ILE A 698LEU A 734 | None | 1.18A | 4j26B-4blaA:undetectable | 4j26B-4blaA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dej | GLUTATHIONES-TRANSFERASERELATED PROTEIN (Idiomarinaloihiensis) |
PF00043(GST_C)PF02798(GST_N) | 5 | LEU A 27GLU A 31LEU A 89ARG A 190ILE A 107 | None | 1.17A | 4j26B-4dejA:undetectable | 4j26B-4dejA:25.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dve | BIOTIN TRANSPORTERBIOY (Lactococcuslactis) |
PF02632(BioY) | 5 | LEU A 97LEU A 69ILE A 20ILE A 21LEU A 75 | NoneNoneNoneBNG A 202 ( 4.2A)BTN A 201 ( 3.8A) | 1.30A | 4j26B-4dveA:undetectable | 4j26B-4dveA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7f | ENOLASE (Trypanosomacruzi) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 340LEU A 341ILE A 381ILE A 393LEU A 388 | None | 1.23A | 4j26B-4g7fA:undetectable | 4j26B-4g7fA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gp1 | POLYPRENYLSYNTHETASE (Pyrobaculumcalidifontis) |
PF00348(polyprenyl_synt) | 5 | LEU A 82LEU A 188ILE A 120ILE A 73LEU A 21 | None | 1.30A | 4j26B-4gp1A:undetectable | 4j26B-4gp1A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gqb | PROTEIN ARGININEN-METHYLTRANSFERASE5 (Homo sapiens) |
PF05185(PRMT5)PF17285(PRMT5_TIM)PF17286(PRMT5_C) | 5 | LEU A 258LEU A 287LEU A 284ILE A 208ILE A 235 | None | 1.30A | 4j26B-4gqbA:undetectable | 4j26B-4gqbA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hsu | LYSINE-SPECIFICHISTONE DEMETHYLASE1B (Homo sapiens) |
PF01593(Amino_oxidase)PF04433(SWIRM)PF07496(zf-CW) | 5 | LEU A 136GLU A 89LEU A 340ILE A 336ILE A 335 | None | 1.23A | 4j26B-4hsuA:undetectable | 4j26B-4hsuA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hsu | LYSINE-SPECIFICHISTONE DEMETHYLASE1B (Homo sapiens) |
PF01593(Amino_oxidase)PF04433(SWIRM)PF07496(zf-CW) | 5 | LEU A 340GLU A 89LEU A 136ILE A 335ILE A 336 | None | 1.31A | 4j26B-4hsuA:undetectable | 4j26B-4hsuA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzu | ENERGY-COUPLINGFACTOR TRANSPORTERTRANSMEMBRANEPROTEIN ECFTPREDICTED MEMBRANEPROTEIN (Lactobacillusbrevis) |
PF02361(CbiQ)PF07155(ECF-ribofla_trS) | 5 | LEU T 171MET T 205LEU T 208ILE S 44LEU S 39 | None | 1.08A | 4j26B-4hzuT:undetectable | 4j26B-4hzuT:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iru | LEPB (Legionellapneumophila) |
no annotation | 5 | LEU A 376GLU A 380ILE A 478ILE A 477LEU A 471 | None | 1.31A | 4j26B-4iruA:undetectable | 4j26B-4iruA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jas | HISTIDINE KINASE (Thermotogamaritima) |
PF00512(HisKA)PF02518(HATPase_c) | 5 | LEU A 406LEU A 398ILE A 365ILE A 370HIS A 456 | None | 1.20A | 4j26B-4jasA:undetectable | 4j26B-4jasA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhj | MIF4GDOMAIN-CONTAININGPROTEIN B (Danio rerio) |
PF02854(MIF4G) | 5 | GLU A 147LEU A 136LEU A 142ILE A 198HIS A 156 | None | 1.29A | 4j26B-4jhjA:undetectable | 4j26B-4jhjA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mps | BETA-GALACTOSIDEALPHA-2,6-SIALYLTRANSFERASE 1 (Rattusnorvegicus) |
PF00777(Glyco_transf_29) | 5 | MET A 328LEU A 323MET A 149LEU A 293ILE A 250 | None | 1.22A | 4j26B-4mpsA:undetectable | 4j26B-4mpsA:22.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 6 | LEU A 286GLU A 290MET A 321LEU A 324ARG A 331ILE A 361 | None | 0.59A | 4j26B-4n1yA:31.3 | 4j26B-4n1yA:38.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1o | RIBONUCLEASE L (Sus scrofa) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 5 | LEU A 108LEU A 106ILE A 96HIS A 62LEU A 61 | None | 1.14A | 4j26B-4o1oA:undetectable | 4j26B-4o1oA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q5n | GLUTHATIONES-TRANSFERASE BLO T8 ISOFORM (Blomiatropicalis) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | MET A 90GLU A 105LEU A 171HIS A 24LEU A 21 | None | 1.30A | 4j26B-4q5nA:undetectable | 4j26B-4q5nA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubs | PENTALENIC ACIDSYNTHASE (Streptomycesavermitilis) |
PF00067(p450) | 5 | LEU A 282GLU A 279MET A 274ILE A 250LEU A 257 | NonePEG A 511 ( 4.4A)NoneNoneNone | 1.30A | 4j26B-4ubsA:undetectable | 4j26B-4ubsA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 772MET A 807LEU A 810LEU A 814ARG A 817 | CV7 A1987 ( 4.5A)CV7 A1987 ( 3.9A)CV7 A1987 (-4.0A)CV7 A1987 ( 4.0A)CV7 A1987 (-3.7A) | 0.51A | 4j26B-4udbA:27.7 | 4j26B-4udbA:27.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4usq | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Cellvibrio sp.BR) |
PF13738(Pyr_redox_3) | 5 | GLU A 96LEU A 26ARG A 105ILE A 16ILE A 134 | None | 1.13A | 4j26B-4usqA:undetectable | 4j26B-4usqA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkz | VALINE-TRNA LIGASE (Pseudomonasaeruginosa) |
PF08264(Anticodon_1) | 5 | LEU A 748GLU A 682LEU A 678ILE A 764ILE A 739 | None | 1.28A | 4j26B-4xkzA:undetectable | 4j26B-4xkzA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zvs | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 183ILE A 150LEU A 142 | None | 1.14A | 4j26B-4zvsA:undetectable | 4j26B-4zvsA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5avo | HOMOSERINEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | LEU A 18LEU A 27ILE A 98ILE A 68LEU A 5 | None | 1.22A | 4j26B-5avoA:undetectable | 4j26B-5avoA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gje | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 6 (Homo sapiens) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 5 | LEU A 320LEU A 335ILE A 550ILE A 323LEU A 559 | None | 1.22A | 4j26B-5gjeA:undetectable | 4j26B-5gjeA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hj7 | GLUTAMATE RACEMASE (Mycobacteriumtuberculosis) |
PF01177(Asp_Glu_race) | 5 | GLU A 239ARG A 66ILE A 25ILE A 24LEU A 18 | None | 1.17A | 4j26B-5hj7A:undetectable | 4j26B-5hj7A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hj7 | GLUTAMATE RACEMASE (Mycobacteriumtuberculosis) |
PF01177(Asp_Glu_race) | 5 | GLU A 239LEU A 63ARG A 66ILE A 24LEU A 18 | None | 1.25A | 4j26B-5hj7A:undetectable | 4j26B-5hj7A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijw | GLUTAMATE RACEMASE (Mycolicibacteriumsmegmatis) |
PF01177(Asp_Glu_race) | 5 | GLU A 243LEU A 63ARG A 66ILE A 24LEU A 18 | None | 1.26A | 4j26B-5ijwA:undetectable | 4j26B-5ijwA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ix1 | MORC FAMILY CW-TYPEZINC FINGER PROTEIN3 (Mus musculus) |
PF07496(zf-CW)PF13589(HATPase_c_3) | 5 | LEU A 19MET A 80LEU A 81ILE A 198ILE A 196 | NoneANP A 502 (-3.1A)NoneNoneNone | 1.29A | 4j26B-5ix1A:undetectable | 4j26B-5ix1A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jhq | TANKYRASE-1 (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2)PF13606(Ank_3) | 5 | LEU A 267LEU A 269ILE A 251HIS A 221LEU A 220 | None | 1.18A | 4j26B-5jhqA:undetectable | 4j26B-5jhqA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l22 | ABC TRANSPORTER(HLYB SUBFAMILY) (Aquifexaeolicus) |
no annotation | 5 | GLU B 391MET B 354LEU B 334ILE B 491ILE B 522 | None | 1.27A | 4j26B-5l22B:undetectable | 4j26B-5l22B:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5p | PRE-MRNA-SPLICINGHELICASE BRR2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | LEU A 670LEU A 518ILE A 908HIS A 640LEU A 638 | None | 1.12A | 4j26B-5m5pA:undetectable | 4j26B-5m5pA:8.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrg | TAR DNA-BINDINGPROTEIN 43 (Homo sapiens) |
no annotation | 5 | LEU A 68LEU A 53ILE A 30ILE A 17LEU A 39 | None | 1.29A | 4j26B-5mrgA:undetectable | 4j26B-5mrgA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nkm | PROTEIN SMG-8 (Caenorhabditiselegans) |
PF10220(Smg8_Smg9) | 5 | LEU E 188LEU E 242ILE E 132ILE E 225LEU E 136 | None | 1.21A | 4j26B-5nkmE:undetectable | 4j26B-5nkmE:21.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 294LEU A 301GLU A 305LEU A 343ARG A 346ILE A 373 | NoneEST A 601 ( 4.3A)EST A 601 (-2.4A)EST A 601 ( 4.4A)EST A 601 (-4.1A)None | 1.50A | 4j26B-5toaA:34.0 | 4j26B-5toaA:99.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 12 | MET A 295LEU A 301GLU A 305MET A 336LEU A 339MET A 340LEU A 343ARG A 346ILE A 373ILE A 376HIS A 475LEU A 476 | EST A 601 ( 4.4A)EST A 601 ( 4.3A)EST A 601 (-2.4A)EST A 601 ( 3.7A)EST A 601 (-3.9A)EST A 601 ( 4.8A)EST A 601 ( 4.4A)EST A 601 (-4.1A)NoneEST A 601 ( 4.4A)EST A 601 (-4.4A)EST A 601 (-3.5A) | 0.36A | 4j26B-5toaA:34.0 | 4j26B-5toaA:99.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 336LEU A 339MET A 340LEU A 343ARG A 346LEU A 490 | EST A 601 ( 3.7A)EST A 601 (-3.9A)EST A 601 ( 4.8A)EST A 601 ( 4.4A)EST A 601 (-4.1A)None | 1.43A | 4j26B-5toaA:34.0 | 4j26B-5toaA:99.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4h | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 5 | LEU A 96GLU A 168LEU A 195ILE A 39LEU A 34 | None | 1.04A | 4j26B-5u4hA:undetectable | 4j26B-5u4hA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ufk | EFFECTOR PROTEINSIDK (Legionellapneumophila) |
no annotation | 5 | MET A 115MET A 103LEU A 107ILE A 36LEU A 94 | None | 1.21A | 4j26B-5ufkA:undetectable | 4j26B-5ufkA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ulj | RAI1 (Scheffersomycesstipitis) |
PF08652(RAI1) | 5 | MET A 111MET A 80LEU A 83ILE A 104LEU A 127 | None | 1.07A | 4j26B-5uljA:undetectable | 4j26B-5uljA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | GLU A 690LEU A 666ILE A 862ILE A 861LEU A 716 | None | 0.97A | 4j26B-5wblA:undetectable | 4j26B-5wblA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wro | ENOLASE (Drosophilamelanogaster) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | LEU A 408LEU A 409ILE A 449ILE A 461LEU A 456 | None | 1.22A | 4j26B-5wroA:undetectable | 4j26B-5wroA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbf | UNCONVENTIONALMYOSIN-VIIB (Homo sapiens) |
PF00373(FERM_M)PF00784(MyTH4) | 5 | LEU A1611LEU A1654ILE A1674ILE A1670LEU A1649 | None | 1.27A | 4j26B-5xbfA:undetectable | 4j26B-5xbfA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yq5 | OSTEOMODULIN (Homo sapiens) |
no annotation | 5 | MET A 182LEU A 164LEU A 168LEU A 148ILE A 174 | None | 1.16A | 4j26B-5yq5A:undetectable | 4j26B-5yq5A:15.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITALPHA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 5 | GLU C 131LEU C 294ARG C 297ILE C 199LEU C 235 | None | 1.15A | 4j26B-6fkhC:undetectable | 4j26B-6fkhC:16.09 |