SIMILAR PATTERNS OF AMINO ACIDS FOR 4IQQ_D_D16D402_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1am5 | PEPSIN (Gadus morhua) |
PF00026(Asp) | 5 | ASP A 303LEU A 306GLY A 302PHE A 301TYR A 14 | None | 1.22A | 4iqqD-1am5A:undetectable | 4iqqD-1am5A:22.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bsf | THYMIDYLATE SYNTHASEA (Bacillussubtilis) |
PF00303(Thymidylat_synt) | 6 | LYS A 61ILE A 93ASP A 184GLY A 188PHE A 191TYR A 224 | None | 1.08A | 4iqqD-1bsfA:30.6 | 4iqqD-1bsfA:34.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c0a | ASPARTYL TRNASYNTHETASE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | ASP A 536LEU A 535GLY A 534PHE A 533 | NoneNoneAMO A 831 (-3.4A)None | 0.76A | 4iqqD-1c0aA:undetectable | 4iqqD-1c0aA:21.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ci7 | PROTEIN (THYMIDYLATESYNTHASE) (Pneumocystiscarinii) |
PF00303(Thymidylat_synt) | 6 | ILE A 86ASP A 202LEU A 205GLY A 206PHE A 209TYR A 242 | CB3 A 768 (-3.6A)CB3 A 768 ( 3.6A)CB3 A 768 ( 4.4A)UMP A 767 (-3.7A)CB3 A 768 (-3.6A)CB3 A 768 ( 4.7A) | 0.63A | 4iqqD-1ci7A:40.0 | 4iqqD-1ci7A:53.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cov | COXSACKIEVIRUS COATPROTEIN (Enterovirus B) |
PF00073(Rhv) | 4 | ILE 3 114LEU 3 104GLY 3 101PHE 3 95 | None | 0.69A | 4iqqD-1cov3:undetectable | 4iqqD-1cov3:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6h | CHALCONE SYNTHASE (Medicago sativa) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | ILE A 114LEU A 150GLY A 149TYR A 153 | None | 0.86A | 4iqqD-1d6hA:0.0 | 4iqqD-1d6hA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6n | PROTEIN(HYPOXANTHINE-GUANINEPHOSPHORIBOSYLTRANSFERASE) (Homo sapiens) |
PF00156(Pribosyltran) | 4 | TYR A 194ILE A 207GLY A 189PHE A 198 | None | 0.87A | 4iqqD-1d6nA:0.0 | 4iqqD-1d6nA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7e | PHOTOACTIVE YELLOWPROTEIN (Halorhodospirahalophila) |
PF00989(PAS) | 5 | TYR A 42ILE A 31ASP A 34GLY A 37PHE A 62 | HC4 A 126 (-4.2A)NoneNoneNoneHC4 A 126 (-4.7A) | 1.46A | 4iqqD-1d7eA:0.5 | 4iqqD-1d7eA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 4 | TYR A 195ILE A 202GLY A 153PHE A 154 | None | 0.89A | 4iqqD-1e6zA:0.0 | 4iqqD-1e6zA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ei5 | D-AMINOPEPTIDASE (Ochrobactrumanthropi) |
PF00144(Beta-lactamase)PF07930(DAP_B) | 4 | TYR A 20ILE A 16GLY A 24PHE A 312 | None | 0.89A | 4iqqD-1ei5A:undetectable | 4iqqD-1ei5A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 5 | TYR A 162ILE A 177ASP A 169GLY A 170PHE A 164 | None | 1.49A | 4iqqD-1fbwA:undetectable | 4iqqD-1fbwA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g6q | HNRNP ARGININEN-METHYLTRANSFERASE (Saccharomycescerevisiae) |
PF06325(PrmA) | 4 | TYR 1 178ILE 1 206LEU 1 173GLY 1 253 | None | 0.72A | 4iqqD-1g6q1:undetectable | 4iqqD-1g6q1:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gxl | CHROMOSOMESEGREGATION SMCPROTEIN (Thermotogamaritima) |
PF06470(SMC_hinge) | 4 | ILE A 524LEU A 609GLY A 610PHE A 614 | None | 0.85A | 4iqqD-1gxlA:undetectable | 4iqqD-1gxlA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | ILE A 325LEU A 301GLY A 268PHE A 334 | None | 0.89A | 4iqqD-1hkkA:undetectable | 4iqqD-1hkkA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htw | HI0065 (Haemophilusinfluenzae) |
PF02367(TsaE) | 4 | ILE A 24ASP A 126LEU A 148GLY A 149 | None | 0.85A | 4iqqD-1htwA:undetectable | 4iqqD-1htwA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hv5 | STROMELYSIN 3 (Mus musculus) |
PF00413(Peptidase_M10) | 4 | ILE A 159LEU A 225GLY A 222PHE A 221 | None | 0.80A | 4iqqD-1hv5A:undetectable | 4iqqD-1hv5A:20.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvy | THYMIDYLATE SYNTHASE (Homo sapiens) |
PF00303(Thymidylat_synt) | 6 | ILE A 108ASP A 218LEU A 221GLY A 222PHE A 225TYR A 258 | D16 A 414 (-3.7A)D16 A 414 ( 3.6A)D16 A 414 (-4.0A)D16 A 414 (-3.3A)D16 A 414 (-3.6A)UMP A 314 ( 4.4A) | 0.59A | 4iqqD-1hvyA:40.8 | 4iqqD-1hvyA:62.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvy | THYMIDYLATE SYNTHASE (Homo sapiens) |
PF00303(Thymidylat_synt) | 5 | LYS A 77ILE A 108GLY A 222PHE A 225TYR A 258 | D16 A 414 ( 4.3A)D16 A 414 (-3.7A)D16 A 414 (-3.3A)D16 A 414 (-3.6A)UMP A 314 ( 4.4A) | 1.07A | 4iqqD-1hvyA:40.8 | 4iqqD-1hvyA:62.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ize | ASPARTIC PROTEINASE (Aspergillusoryzae) |
PF00026(Asp) | 5 | ASP A 300LEU A 303GLY A 299PHE A 298TYR A 17 | None | 1.16A | 4iqqD-1izeA:undetectable | 4iqqD-1izeA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 4 | ASP A 655GLY A 658PHE A 661TYR A 598 | None | 0.86A | 4iqqD-1j1wA:undetectable | 4iqqD-1j1wA:19.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j3j | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00303(Thymidylat_synt) | 5 | LYS C 372ASP C 513LEU C 516GLY C 517TYR C 553 | NoneUMP C 611 (-4.9A)NoneUMP C 611 (-3.5A)UMP C 611 (-4.9A) | 1.12A | 4iqqD-1j3jC:38.9 | 4iqqD-1j3jC:49.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j3j | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00303(Thymidylat_synt) | 5 | LYS C 372ILE C 403ASP C 513GLY C 517TYR C 553 | NoneNoneUMP C 611 (-4.9A)UMP C 611 (-3.5A)UMP C 611 (-4.9A) | 1.08A | 4iqqD-1j3jC:38.9 | 4iqqD-1j3jC:49.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j8s | PYELONEPHRITICADHESIN (Escherichiacoli) |
PF03627(PapG_N) | 4 | TYR A 7ASP A 11LEU A 9GLY A 10 | None | 0.88A | 4iqqD-1j8sA:undetectable | 4iqqD-1j8sA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mda | METHYLAMINEDEHYDROGENASE (HEAVYSUBUNIT) (Paracoccusdenitrificans) |
PF06433(Me-amine-dh_H) | 4 | LYS H 271TYR H 221ASP H 237GLY H 223 | None | 0.87A | 4iqqD-1mdaH:undetectable | 4iqqD-1mdaH:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzu | PPR (Rhodospirillumcentenum) |
PF00989(PAS) | 5 | TYR A 42ILE A 31ASP A 34GLY A 37PHE A 62 | HC4 A 130 (-4.6A)NoneNoneNoneNone | 1.49A | 4iqqD-1mzuA:undetectable | 4iqqD-1mzuA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n71 | AAC(6')-II (Enterococcusfaecium) |
PF00583(Acetyltransf_1) | 4 | TYR A 144ILE A 154LEU A 109GLY A 110 | None | 0.63A | 4iqqD-1n71A:undetectable | 4iqqD-1n71A:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nnl | L-3-PHOSPHOSERINEPHOSPHATASE (Homo sapiens) |
PF00702(Hydrolase) | 5 | LYS A 158ILE A 91ASP A 179GLY A 178PHE A 19 | CL A1500 (-3.2A)None CA A2001 (-2.9A)NoneNone | 1.42A | 4iqqD-1nnlA:undetectable | 4iqqD-1nnlA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odv | PHOTOACTIVE YELLOWPROTEIN (Halorhodospirahalophila) |
PF00989(PAS) | 5 | TYR A 42ILE A 31ASP A 34GLY A 37PHE A 62 | HC4 A 126 (-4.2A)NoneNoneNoneHC4 A 126 ( 4.9A) | 1.48A | 4iqqD-1odvA:undetectable | 4iqqD-1odvA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pmj | BETA-1,4-MANNANASE (Caldicellulosiruptorsaccharolyticus) |
PF09212(CBM27) | 4 | ILE X 173ASP X 61GLY X 164PHE X 103 | None | 0.89A | 4iqqD-1pmjX:undetectable | 4iqqD-1pmjX:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q6y | HYPOTHETICAL PROTEINYFDW (Escherichiacoli) |
PF02515(CoA_transf_3) | 4 | TYR A 225ASP A 239GLY A 238PHE A 237 | None | 0.85A | 4iqqD-1q6yA:undetectable | 4iqqD-1q6yA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qox | BETA-GLUCOSIDASE (Bacilluscirculans) |
PF00232(Glyco_hydro_1) | 5 | TYR A 146ILE A 80ASP A 99LEU A 98GLY A 97 | None | 1.20A | 4iqqD-1qoxA:undetectable | 4iqqD-1qoxA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rgi | GELSOLIN (Equus caballus) |
PF00626(Gelsolin) | 4 | TYR G 133ILE G 70LEU G 138GLY G 60 | None | 0.87A | 4iqqD-1rgiG:undetectable | 4iqqD-1rgiG:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhy | IMIDAZOLE GLYCEROLPHOSPHATEDEHYDRATASE (Cryptococcusneoformans) |
PF00475(IGPD) | 4 | ILE A 181LEU A 81GLY A 82PHE A 85 | None | 0.83A | 4iqqD-1rhyA:undetectable | 4iqqD-1rhyA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rtr | GERANYLTRANSTRANSFERASE (Staphylococcusaureus) |
PF00348(polyprenyl_synt) | 4 | ILE A 45LEU A 210GLY A 211PHE A 214 | None | 0.45A | 4iqqD-1rtrA:undetectable | 4iqqD-1rtrA:25.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb3 | 4-HYDROXYBENZOYL-COAREDUCTASE ALPHASUBUNIT (Thaueraaromatica) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | ILE A 534ASP A 714GLY A 720PHE A 719 | None | 0.88A | 4iqqD-1sb3A:undetectable | 4iqqD-1sb3A:17.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tis | THYMIDYLATE SYNTHASE (Escherichiavirus T4) |
PF00303(Thymidylat_synt) | 6 | LYS A 48ASP A 179LEU A 182GLY A 183PHE A 186TYR A 219 | None | 1.32A | 4iqqD-1tisA:30.3 | 4iqqD-1tisA:39.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uch | UBIQUITIN C-TERMINALHYDROLASE UCH-L3 (Homo sapiens) |
PF01088(Peptidase_C12) | 4 | ILE A 225LEU A 100GLY A 99PHE A 170 | None | 0.85A | 4iqqD-1uchA:undetectable | 4iqqD-1uchA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1upn | ECHOVIRUS 11 COATPROTEIN VP3 (Enterovirus B) |
PF00073(Rhv) | 4 | ILE C 114LEU C 104GLY C 101PHE C 95 | None | 0.79A | 4iqqD-1upnC:undetectable | 4iqqD-1upnC:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v02 | DHURRINASE (Sorghum bicolor) |
PF00232(Glyco_hydro_1) | 4 | TYR A 166LEU A 150GLY A 156PHE A 157 | None | 0.89A | 4iqqD-1v02A:undetectable | 4iqqD-1v02A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 4 | TYR A 257LEU A 277GLY A 278PHE A 253 | None | 0.84A | 4iqqD-1v19A:undetectable | 4iqqD-1v19A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgm | 378AA LONGHYPOTHETICAL CITRATESYNTHASE (Sulfurisphaeratokodaii) |
PF00285(Citrate_synt) | 4 | TYR A 310ASP A 314GLY A 256PHE A 257 | NoneGOL A 401 ( 4.5A)NoneNone | 0.77A | 4iqqD-1vgmA:undetectable | 4iqqD-1vgmA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgp | 373AA LONGHYPOTHETICAL CITRATESYNTHASE (Sulfurisphaeratokodaii) |
PF00285(Citrate_synt) | 4 | TYR A 306ASP A 310GLY A 251PHE A 252 | None | 0.89A | 4iqqD-1vgpA:undetectable | 4iqqD-1vgpA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7m | ATPPHOSPHORIBOSYLTRANSFERASE REGULATORYSUBUNIT (Lactococcuslactis) |
PF13393(tRNA-synt_His) | 4 | ILE A 129GLY A 288PHE A 307TYR A 268 | None | 0.82A | 4iqqD-1z7mA:undetectable | 4iqqD-1z7mA:21.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 5 | ILE A 100LEU A 222GLY A 223PHE A 226TYR A 259 | CB3 A2351 (-3.6A)CB3 A2351 (-4.1A)CB3 A2351 ( 3.2A)CB3 A2351 (-3.8A)CB3 A2351 ( 4.3A) | 1.06A | 4iqqD-2aazA:undetectable | 4iqqD-2aazA:49.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 6 | LYS A 69ILE A 100ASP A 219LEU A 222GLY A 223TYR A 259 | CB3 A2351 ( 4.1A)CB3 A2351 (-3.6A)CB3 A2351 ( 3.6A)CB3 A2351 (-4.1A)CB3 A2351 ( 3.2A)CB3 A2351 ( 4.3A) | 1.12A | 4iqqD-2aazA:undetectable | 4iqqD-2aazA:49.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amy | PHOSPHOMANNOMUTASE 2 (Homo sapiens) |
PF03332(PMM) | 4 | ILE A 240ASP A 209GLY A 208PHE A 207 | None | 0.81A | 4iqqD-2amyA:undetectable | 4iqqD-2amyA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 4 | LEU A 185GLY A 180PHE A 179TYR A 3 | None | 0.88A | 4iqqD-2cb1A:undetectable | 4iqqD-2cb1A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6y | PUTATIVE TETR FAMILYREGULATORY PROTEIN (Streptomycescoelicolor) |
PF00440(TetR_N) | 4 | LEU A 55GLY A 53PHE A 56TYR A 46 | None | 0.89A | 4iqqD-2d6yA:undetectable | 4iqqD-2d6yA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exr | CYTOKININDEHYDROGENASE 7 (Arabidopsisthaliana) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | ILE A 339ASP A 272LEU A 320GLY A 319 | None | 0.80A | 4iqqD-2exrA:undetectable | 4iqqD-2exrA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fq4 | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Bacillus cereus) |
PF00440(TetR_N)PF16859(TetR_C_11) | 5 | TYR A 124ILE A 103ASP A 113LEU A 116GLY A 110 | None | 1.38A | 4iqqD-2fq4A:undetectable | 4iqqD-2fq4A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gxf | HYPOTHETICAL PROTEINYYBH (Bacillussubtilis) |
PF13474(SnoaL_3) | 4 | TYR A 104ILE A 9LEU A 72PHE A 106 | MES A 201 (-3.3A)MES A 201 (-4.2A)NoneMES A 201 (-4.7A) | 0.87A | 4iqqD-2gxfA:undetectable | 4iqqD-2gxfA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h12 | CITRATE SYNTHASE (Acetobacteraceti) |
PF00285(Citrate_synt) | 4 | TYR A 367ASP A 371GLY A 310PHE A 311 | NoneCMX A5001 (-2.8A)CMX A5001 (-3.4A)None | 0.80A | 4iqqD-2h12A:undetectable | 4iqqD-2h12A:22.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 6 | ILE A 316ASP A 426LEU A 429GLY A 430PHE A 433TYR A 466 | NoneNoneNone DU A 611 (-3.5A)None DU A 611 (-4.6A) | 0.77A | 4iqqD-2h2qA:40.2 | 4iqqD-2h2qA:36.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | LYS A 285ILE A 316LEU A 429GLY A 430PHE A 433 | NoneNoneNone DU A 611 (-3.5A)None | 0.77A | 4iqqD-2h2qA:40.2 | 4iqqD-2h2qA:36.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6t | CANDIDAPEPSIN-3 (Candidaalbicans) |
PF00026(Asp) | 5 | ILE A 272ASP A 308LEU A 311GLY A 307TYR A 14 | None | 1.35A | 4iqqD-2h6tA:undetectable | 4iqqD-2h6tA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hh6 | BH3980 PROTEIN (Bacillushalodurans) |
PF06304(DUF1048) | 5 | ILE A 38ASP A 63LEU A 62GLY A 59PHE A 58 | None | 1.27A | 4iqqD-2hh6A:undetectable | 4iqqD-2hh6A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i53 | CYCLIN K (Homo sapiens) |
PF00134(Cyclin_N)PF02984(Cyclin_C) | 4 | ILE A 117ASP A 134GLY A 133PHE A 132 | None | 0.86A | 4iqqD-2i53A:undetectable | 4iqqD-2i53A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2idv | EUKARYOTICTRANSLATIONINITIATION FACTOR4E-1 (Triticumaestivum) |
PF01652(IF4E) | 4 | ILE A 166ASP A 148GLY A 147PHE A 144 | None | 0.73A | 4iqqD-2idvA:undetectable | 4iqqD-2idvA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivg | CYANATE LYASE (Escherichiacoli) |
PF02560(Cyanate_lyase) | 4 | ILE A 121ASP A 118GLY A 117PHE A 116 | None | 0.87A | 4iqqD-2ivgA:undetectable | 4iqqD-2ivgA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jbh | PHOSPHORIBOSYLTRANSFERASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00156(Pribosyltran) | 4 | TYR A 202ILE A 215GLY A 197PHE A 206 | None | 0.75A | 4iqqD-2jbhA:undetectable | 4iqqD-2jbhA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k4j | PUTATIVETRANSCRIPTIONALREGULATOR (Helicobacterpylori) |
PF00486(Trans_reg_C) | 4 | ILE A 23LEU A 113GLY A 58TYR A 111 | None | 0.87A | 4iqqD-2k4jA:undetectable | 4iqqD-2k4jA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kxp | F-ACTIN-CAPPINGPROTEIN SUBUNITALPHA-1F-ACTIN-CAPPINGPROTEIN SUBUNIT BETAISOFORMS 1 AND 2 (Gallus gallus) |
PF01115(F_actin_cap_B)PF01267(F-actin_cap_A) | 4 | TYR A 198ILE B 531LEU B 489GLY B 490 | None | 0.80A | 4iqqD-2kxpA:undetectable | 4iqqD-2kxpA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ntt | STAPHYLOCOCCALENTEROTOXIN K (Staphylococcusaureus) |
PF02876(Stap_Strp_tox_C) | 4 | TYR A 137ILE A 99LEU A 180GLY A 164 | NoneNoneNoneEDO A7009 (-4.7A) | 0.83A | 4iqqD-2nttA:undetectable | 4iqqD-2nttA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nux | 2-KETO-3-DEOXYGLUCONATE/2-KETO-3-DEOXY-6-PHOSPHO GLUCONATEALDOLASE (Sulfolobusacidocaldarius) |
PF00701(DHDPS) | 4 | TYR A 183ILE A 211ASP A 190GLY A 191 | None | 0.89A | 4iqqD-2nuxA:undetectable | 4iqqD-2nuxA:24.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1o | PUTATIVE FARNESYLPYROPHOSPHATESYNTHASE (Cryptosporidiumparvum) |
PF00348(polyprenyl_synt) | 4 | ILE A 355GLY A 247PHE A 249TYR A 214 | None | 0.85A | 4iqqD-2o1oA:undetectable | 4iqqD-2o1oA:19.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oip | CHAIN A, CRYSTALSTRUCTURE OF DHFR (Cryptosporidiumhominis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ILE A 315ASP A 426LEU A 429GLY A 430TYR A 466 | CB3 A 604 ( 3.7A)CB3 A 604 ( 3.9A)CB3 A 604 ( 4.4A)CB3 A 604 ( 3.4A)UMP A 603 ( 4.3A) | 0.71A | 4iqqD-2oipA:39.4 | 4iqqD-2oipA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oip | CHAIN A, CRYSTALSTRUCTURE OF DHFR (Cryptosporidiumhominis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ILE A 315LEU A 429GLY A 430PHE A 433TYR A 466 | CB3 A 604 ( 3.7A)CB3 A 604 ( 4.4A)CB3 A 604 ( 3.4A)CB3 A 604 ( 3.9A)UMP A 603 ( 4.3A) | 1.19A | 4iqqD-2oipA:39.4 | 4iqqD-2oipA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oip | CHAIN A, CRYSTALSTRUCTURE OF DHFR (Cryptosporidiumhominis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | LYS A 284ILE A 315ASP A 426GLY A 430TYR A 466 | CB3 A 604 ( 4.7A)CB3 A 604 ( 3.7A)CB3 A 604 ( 3.9A)CB3 A 604 ( 3.4A)UMP A 603 ( 4.3A) | 1.05A | 4iqqD-2oipA:39.4 | 4iqqD-2oipA:32.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p76 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Staphylococcusaureus) |
PF03009(GDPD) | 4 | TYR A 166ILE A 156LEU A 90TYR A 176 | None | 0.80A | 4iqqD-2p76A:undetectable | 4iqqD-2p76A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfc | PLCR PROTEIN (Bacillusthuringiensis) |
PF01381(HTH_3) | 4 | ILE A 135ASP A 176LEU A 177GLY A 174 | None | 0.85A | 4iqqD-2qfcA:undetectable | 4iqqD-2qfcA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfr | PURPLE ACIDPHOSPHATASE (Phaseolusvulgaris) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | ILE A 247LEU A 132GLY A 131PHE A 130 | None | 0.81A | 4iqqD-2qfrA:undetectable | 4iqqD-2qfrA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r26 | CITRATE SYNTHASE (Thermoplasmaacidophilum) |
PF00285(Citrate_synt) | 4 | ILE A 251ASP A 301GLY A 303PHE A 307 | NoneNoneNoneCMC A 701 ( 4.3A) | 0.85A | 4iqqD-2r26A:undetectable | 4iqqD-2r26A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r26 | CITRATE SYNTHASE (Thermoplasmaacidophilum) |
PF00285(Citrate_synt) | 4 | TYR A 313ASP A 317GLY A 259PHE A 260 | NoneCMC A 701 (-2.7A)CMC A 701 (-3.3A)None | 0.82A | 4iqqD-2r26A:undetectable | 4iqqD-2r26A:20.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2tdd | THYMIDYLATE SYNTHASE (Lactobacilluscasei) |
PF00303(Thymidylat_synt) | 4 | ASP A 221LEU A 224GLY A 225TYR A 261 | UFP A 529 (-4.7A)THF A 568 (-3.6A)UFP A 529 ( 4.0A)UFP A 529 (-4.7A) | 0.89A | 4iqqD-2tddA:32.5 | 4iqqD-2tddA:41.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2tdd | THYMIDYLATE SYNTHASE (Lactobacilluscasei) |
PF00303(Thymidylat_synt) | 4 | ILE A 81ASP A 221GLY A 225TYR A 261 | THF A 568 ( 4.8A)UFP A 529 (-4.7A)UFP A 529 ( 4.0A)UFP A 529 (-4.7A) | 0.69A | 4iqqD-2tddA:32.5 | 4iqqD-2tddA:41.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2tdd | THYMIDYLATE SYNTHASE (Lactobacilluscasei) |
PF00303(Thymidylat_synt) | 4 | LEU A 224GLY A 225PHE A 228TYR A 261 | THF A 568 (-3.6A)UFP A 529 ( 4.0A)THF A 568 (-4.8A)UFP A 529 (-4.7A) | 0.81A | 4iqqD-2tddA:32.5 | 4iqqD-2tddA:41.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vod | LUPUS LA PROTEIN (Homo sapiens) |
PF00076(RRM_1)PF05383(La) | 4 | ILE A 40ASP A 27GLY A 26PHE A 25 | None | 0.88A | 4iqqD-2vodA:undetectable | 4iqqD-2vodA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5s | PROCESSED GLYCEROLPHOSPHATELIPOTEICHOIC ACIDSYNTHASE (Staphylococcusaureus) |
PF00884(Sulfatase) | 4 | TYR A 455ILE A 252LEU A 448TYR A 441 | None | 0.89A | 4iqqD-2w5sA:undetectable | 4iqqD-2w5sA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 5 | ASP A 300LEU A 303GLY A 299PHE A 298TYR A 17 | None | 1.20A | 4iqqD-2wedA:undetectable | 4iqqD-2wedA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wmc | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Pisum sativum) |
PF01652(IF4E) | 4 | ILE A 179ASP A 161GLY A 160PHE A 157 | None | 0.65A | 4iqqD-2wmcA:undetectable | 4iqqD-2wmcA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y4o | PHENYLACETATE-COENZYME A LIGASE (Burkholderiacenocepacia) |
PF00501(AMP-binding)PF14535(AMP-binding_C_2) | 4 | ILE A 240GLY A 147PHE A 140TYR A 109 | DLL A1441 (-4.7A)DLL A1441 (-3.6A)DLL A1441 (-3.6A)None | 0.78A | 4iqqD-2y4oA:undetectable | 4iqqD-2y4oA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxx | DIAMINOPIMELATEDECARBOXYLASE (Thermotogamaritima) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ILE A 173ASP A 162LEU A 161PHE A 164 | None | 0.86A | 4iqqD-2yxxA:undetectable | 4iqqD-2yxxA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a31 | PROBABLETHREONYL-TRNASYNTHETASE 1 (Aeropyrumpernix) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 4 | ILE A 18LEU A 154GLY A 322TYR A 152 | None | 0.80A | 4iqqD-3a31A:undetectable | 4iqqD-3a31A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bo7 | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECYCLOPHILIN-TYPE (Toxoplasmagondii) |
PF00160(Pro_isomerase) | 4 | ILE A 121ASP A 144LEU A 143GLY A 142 | None | 0.71A | 4iqqD-3bo7A:undetectable | 4iqqD-3bo7A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dls | PASDOMAIN-CONTAININGSERINE/THREONINE-PROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | LYS A1023ILE A1065ASP A1069LEU A1068 | NoneADP A 1 (-4.0A)NoneNone | 0.77A | 4iqqD-3dlsA:undetectable | 4iqqD-3dlsA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emy | TRICHODERMA REESEIASPARTIC PROTEASE (Trichodermareesei) |
PF00026(Asp) | 5 | ASP A 304LEU A 307GLY A 303PHE A 302TYR A 14 | None | 1.15A | 4iqqD-3emyA:undetectable | 4iqqD-3emyA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f0h | AMINOTRANSFERASE ([Eubacterium]rectale) |
PF00266(Aminotran_5) | 4 | TYR A 121LEU A 129GLY A 128PHE A 126 | GOL A 361 (-4.1A)NoneNoneNone | 0.75A | 4iqqD-3f0hA:undetectable | 4iqqD-3f0hA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fv3 | SAPP1P-SECRETEDASPARTIC PROTEASE 1 (Candidaparapsilosis) |
PF00026(Asp) | 5 | ILE A 276ASP A 306LEU A 309GLY A 305TYR A 14 | None | 1.33A | 4iqqD-3fv3A:undetectable | 4iqqD-3fv3A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3heb | RESPONSE REGULATORRECEIVER DOMAINPROTEIN (CHEY) (Rhodospirillumrubrum) |
PF00072(Response_reg) | 4 | ILE A 10LEU A 135GLY A 136PHE A 139 | None | 0.70A | 4iqqD-3hebA:undetectable | 4iqqD-3hebA:19.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ix6 | THYMIDYLATE SYNTHASE (Brucellamelitensis) |
PF00303(Thymidylat_synt) | 4 | ASP A 169LEU A 172GLY A 173TYR A 209 | None | 0.75A | 4iqqD-3ix6A:32.3 | 4iqqD-3ix6A:38.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ix6 | THYMIDYLATE SYNTHASE (Brucellamelitensis) |
PF00303(Thymidylat_synt) | 4 | ILE A 79ASP A 169GLY A 173TYR A 209 | None | 0.57A | 4iqqD-3ix6A:32.3 | 4iqqD-3ix6A:38.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iyj | MAJOR CAPSID PROTEINL1 (Deltapapillomavirus4) |
no annotation | 4 | ILE F 99LEU F 461GLY F 462PHE F 465 | None | 0.79A | 4iqqD-3iyjF:undetectable | 4iqqD-3iyjF:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxz | ALKYLPURINE DNAGLYCOSYLASE ALKD (Bacillus cereus) |
PF08713(DNA_alkylation) | 5 | ILE A 131ASP A 122LEU A 125GLY A 121PHE A 153 | None | 1.31A | 4iqqD-3jxzA:undetectable | 4iqqD-3jxzA:19.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kgb | THYMIDYLATE SYNTHASE1/2 (Encephalitozooncuniculi) |
PF00303(Thymidylat_synt) | 4 | LEU A 200GLY A 201PHE A 204TYR A 237 | None | 0.64A | 4iqqD-3kgbA:35.9 | 4iqqD-3kgbA:50.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | ASP A 416LEU A 419GLY A 420TYR A 456 | None | 0.64A | 4iqqD-3kjrA:38.6 | 4iqqD-3kjrA:35.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq5 | HYPOTHETICALCYTOSOLIC PROTEIN (Coxiellaburnetii) |
PF07515(TraI_2_C) | 4 | ILE A 367LEU A 320GLY A 319PHE A 318 | None | 0.81A | 4iqqD-3kq5A:undetectable | 4iqqD-3kq5A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m3p | GLUTAMINE AMIDOTRANSFERASE (Methylobacillusflagellatus) |
PF00117(GATase) | 4 | TYR A 233ILE A 86LEU A 240GLY A 239 | None | 0.75A | 4iqqD-3m3pA:undetectable | 4iqqD-3m3pA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7t | CYCLOPHILIN A (Moniliophthoraperniciosa) |
PF00160(Pro_isomerase) | 4 | ILE A 112ASP A 135LEU A 134GLY A 133 | None | 0.81A | 4iqqD-3o7tA:undetectable | 4iqqD-3o7tA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3on4 | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Legionellapneumophila) |
PF00440(TetR_N) | 4 | TYR A 25ILE A 120LEU A 105GLY A 106 | None | 0.77A | 4iqqD-3on4A:undetectable | 4iqqD-3on4A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3org | CMCLC (Cyanidioschyzonmerolae) |
PF00654(Voltage_CLC) | 4 | ILE A 436LEU A 333GLY A 334PHE A 337 | None | 0.77A | 4iqqD-3orgA:undetectable | 4iqqD-3orgA:18.67 |