SIMILAR PATTERNS OF AMINO ACIDS FOR 4IOM_A_FOLA608

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		4 ALA A 657
GLU A 510
LEU A 623
LEU A 627
 None
 1.03A 4iomA-1c30A:
2.8		 4iomA-1c30A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crz TOLB PROTEIN

(Escherichia
coli) 		PF04052
(TolB_N)
PF07676
(PD40) 		4 ALA A 147
PRO A 403
LEU A 161
LEU A 193
 None
 0.94A 4iomA-1crzA:
undetectable		 4iomA-1crzA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crz TOLB PROTEIN

(Escherichia
coli) 		PF04052
(TolB_N)
PF07676
(PD40) 		4 ALA A 194
PRO A 184
LEU A 205
LEU A 237
 None
 0.94A 4iomA-1crzA:
undetectable		 4iomA-1crzA:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1eg7 FORMYLTETRAHYDROFOLA
TE SYNTHETASE

(Moorella
thermoacetica) 		PF01268
(FTHFS) 		6 ALA A1383
PRO A1385
GLU A1389
LEU A1392
TYR A1396
TRP A1412
 None
None
None
None
None
SO4  A   7 (-3.2A)
 0.28A 4iomA-1eg7A:
62.7		 4iomA-1eg7A:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iub FUCOSE-SPECIFIC
LECTIN

(Aleuria
aurantia) 		PF07938
(Fungal_lectin) 		4 ALA A 172
PRO A 175
TYR A 133
LEU A 118
 None
 0.98A 4iomA-1iubA:
undetectable		 4iomA-1iubA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3u ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ALA A 148
PRO A 146
LEU A  45
LEU A  49
 None
 1.01A 4iomA-1j3uA:
undetectable		 4iomA-1j3uA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldd ANAPHASE PROMOTING
COMPLEX

(Saccharomyces
cerevisiae) 		PF08672
(ANAPC2) 		4 GLU A 832
LEU A 829
TYR A 825
LEU A 782
 None
 0.86A 4iomA-1lddA:
undetectable		 4iomA-1lddA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 ALA A 344
PRO A 346
LEU A 335
LEU A 339
 None
 0.74A 4iomA-1nneA:
undetectable		 4iomA-1nneA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o1y CONSERVED
HYPOTHETICAL PROTEIN
TM1158

(Thermotoga
maritima) 		PF00117
(GATase) 		4 GLU A  76
LEU A  73
TYR A  69
LEU A  39
 None
 0.99A 4iomA-1o1yA:
undetectable		 4iomA-1o1yA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 ALA A 523
PRO A 530
LEU A  67
LEU A  71
 None
 0.85A 4iomA-1t1uA:
undetectable		 4iomA-1t1uA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txk GLUCANS BIOSYNTHESIS
PROTEIN G

(Escherichia
coli) 		PF04349
(MdoG) 		4 ALA A 214
PRO A 212
LEU A 209
TYR A 218
 None
 0.99A 4iomA-1txkA:
undetectable		 4iomA-1txkA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 ALA A 275
PRO A 303
LEU A 273
LEU A 240
 None
 1.07A 4iomA-1udxA:
3.8		 4iomA-1udxA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf3 HYPOTHETICAL PROTEIN
TT1561

(Thermus
thermophilus) 		PF14582
(Metallophos_3) 		4 ALA A 111
LEU A 140
LEU A 143
TRP A 104
 None
 1.07A 4iomA-1uf3A:
3.3		 4iomA-1uf3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, BETA
SUBUNIT

(Geobacillus
stearothermophilus) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 PRO B  78
GLU B 171
LEU B 157
LEU B  13
 None
 1.07A 4iomA-1w85B:
2.4		 4iomA-1w85B:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xi8 MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN

(Pyrococcus
furiosus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 ALA A  35
PRO A  31
LEU A 166
LEU A 161
 None
 1.03A 4iomA-1xi8A:
undetectable		 4iomA-1xi8A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Lactococcus
lactis) 		PF01634
(HisG) 		4 ALA E 152
GLU E 130
TYR E 124
LEU E  96
 None
 0.98A 4iomA-1z7mE:
undetectable		 4iomA-1z7mE:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z8l GLUTAMATE
CARBOXYPEPTIDASE II

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 ALA A 423
LEU A 117
TYR A 119
TRP A 421
 None
 0.84A 4iomA-1z8lA:
3.9		 4iomA-1z8lA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7n L(+)-MANDELATE
DEHYDROGENASE

(Pseudomonas
putida;
Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 ALA A  95
LEU A 126
TYR A 150
LEU A 118
 None
 1.04A 4iomA-2a7nA:
2.1		 4iomA-2a7nA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN

(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		PF00502
(Phycobilisome)
PF00502
(Phycobilisome) 		4 ALA A   8
PRO A   4
LEU B  98
LEU A  19
 None
 1.02A 4iomA-2c7lA:
undetectable		 4iomA-2c7lA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chq REPLICATION FACTOR C
SMALL SUBUNIT

(Archaeoglobus
fulgidus) 		PF00004
(AAA)
PF08542
(Rep_fac_C) 		4 ALA A 226
PRO A 228
GLU A 233
LEU A 253
 None
 1.03A 4iomA-2chqA:
undetectable		 4iomA-2chqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt9 ASPARTOKINASE

(Thermus
thermophilus) 		PF01842
(ACT)
PF13840
(ACT_7) 		4 ALA A 145
PRO A 141
LEU A  14
LEU A  12
 None
 1.03A 4iomA-2dt9A:
undetectable		 4iomA-2dt9A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fex CONSERVED
HYPOTHETICAL PROTEIN

(Agrobacterium
fabrum) 		PF01965
(DJ-1_PfpI) 		4 ALA A   7
PRO A  37
LEU A  59
LEU A  67
 None
 0.86A 4iomA-2fexA:
4.3		 4iomA-2fexA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go4 UDP-3-O-[3-HYDROXYMY
RISTOYL]
N-ACETYLGLUCOSAMINE
DEACETYLASE

(Aquifex
aeolicus) 		PF03331
(LpxC) 		4 ALA A 147
PRO A 135
LEU A 275
LEU A 271
 None
 0.90A 4iomA-2go4A:
undetectable		 4iomA-2go4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixs SDAI RESTRICTION
ENDONUCLEASE

(Streptomyces
diastaticus) 		PF06616
(BsuBI_PstI_RE) 		4 ALA A 273
PRO A 271
LEU A 275
LEU A 244
 None
 1.00A 4iomA-2ixsA:
undetectable		 4iomA-2ixsA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og9 MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Polaromonas sp.
JS666) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ALA A 289
PRO A 297
LEU A 324
LEU A 320
 None
 0.93A 4iomA-2og9A:
2.6		 4iomA-2og9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uuu ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE

(Dictyostelium
discoideum) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 ALA A 310
LEU A 248
LEU A 244
TRP A 202
 None
 1.00A 4iomA-2uuuA:
undetectable		 4iomA-2uuuA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy0 ENDO-BETA-1,3-GLUCAN
ASE

(Pyrococcus
furiosus) 		PF00722
(Glyco_hydro_16) 		4 ALA A 103
PRO A 281
LEU A 149
LEU A 264
 None
 0.90A 4iomA-2vy0A:
undetectable		 4iomA-2vy0A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8a NUCLEAR
VALOSIN-CONTAINING
PROTEIN-LIKE

(Homo sapiens) 		PF00004
(AAA) 		4 ALA A 780
PRO A 751
LEU A 793
LEU A 758
 None
 0.89A 4iomA-2x8aA:
2.2		 4iomA-2x8aA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwr METALLO-BETA-LACTAMA
SE SUPERFAMILY
PROTEIN

(Thermus
thermophilus) 		PF00753
(Lactamase_B) 		4 PRO A   5
GLU A  13
LEU A   8
LEU A  36
 None
 0.89A 4iomA-2zwrA:
undetectable		 4iomA-2zwrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afl OLIGO ALGINATE LYASE

(Agrobacterium
fabrum) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		4 PRO A  45
LEU A  14
LEU A  96
TRP A  76
 None
 0.99A 4iomA-3aflA:
undetectable		 4iomA-3aflA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bw2 2-NITROPROPANE
DIOXYGENASE

(Streptomyces
ansochromogenes) 		PF03060
(NMO) 		4 ALA A 239
GLU A 343
LEU A 340
LEU A 336
 None
 0.87A 4iomA-3bw2A:
undetectable		 4iomA-3bw2A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgx PUTATIVE
NUCLEOTIDE-DIPHOSPHO
-SUGAR TRANSFERASE

(Desulfovibrio
alaskensis) 		PF09837
(DUF2064) 		4 ALA A 133
LEU A 144
TYR A 143
LEU A 185
 None
 0.90A 4iomA-3cgxA:
undetectable		 4iomA-3cgxA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da8 PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN

(Mycobacterium
tuberculosis) 		PF00551
(Formyl_trans_N) 		4 ALA A  56
PRO A  62
LEU A  30
LEU A  26
 None
None
None
IOD  A 603 (-4.8A)
 1.01A 4iomA-3da8A:
2.4		 4iomA-3da8A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fed GLUTAMATE
CARBOXYPEPTIDASE III

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 ALA A 413
LEU A 107
TYR A 109
TRP A 411
 None
 0.89A 4iomA-3fedA:
2.9		 4iomA-3fedA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 2

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 ALA A  76
PRO A  74
LEU A 125
LEU A 129
 None
 1.07A 4iomA-3hhsA:
undetectable		 4iomA-3hhsA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hlk ACYL-COENZYME A
THIOESTERASE 2,
MITOCHONDRIAL

(Homo sapiens) 		PF04775
(Bile_Hydr_Trans)
PF08840
(BAAT_C) 		4 ALA A 246
PRO A 220
LEU A 277
LEU A 210
 None
 0.92A 4iomA-3hlkA:
undetectable		 4iomA-3hlkA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwr 2-DEHYDROPANTOATE
2-REDUCTASE

(Cupriavidus
pinatubonensis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 ALA A 119
PRO A 147
LEU A  96
LEU A  98
 None
 0.99A 4iomA-3hwrA:
undetectable		 4iomA-3hwrA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i38 PUTATIVE CHAPERONE
DNAJ

(Klebsiella
pneumoniae) 		PF01556
(DnaJ_C) 		4 PRO A 241
GLU A 220
LEU A 216
LEU A 214
 None
 0.96A 4iomA-3i38A:
undetectable		 4iomA-3i38A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6b BETA-AMYLOID-LIKE
PROTEIN

(Caenorhabditis
elegans) 		PF12925
(APP_E2) 		4 ALA A 431
PRO A 429
LEU A 414
LEU A 363
 None
 1.02A 4iomA-3k6bA:
undetectable		 4iomA-3k6bA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE

(Bacteroides
thetaiotaomicron) 		PF03992
(ABM) 		4 ALA A  71
GLU A  55
LEU A  52
TYR A  48
 None
ACT  A 203 (-2.4A)
None
None
 1.05A 4iomA-3kkfA:
undetectable		 4iomA-3kkfA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lr0 SENSOR PROTEIN

(Burkholderia
pseudomallei) 		PF16524
(RisS_PPD) 		4 ALA A  57
GLU A  77
LEU A  73
LEU A  69
 None
 0.97A 4iomA-3lr0A:
undetectable		 4iomA-3lr0A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lsp DEST

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		4 ALA A  20
GLU A  66
LEU A  63
LEU A  59
 None
 0.98A 4iomA-3lspA:
undetectable		 4iomA-3lspA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mru AMINOACYL-HISTIDINE
DIPEPTIDASE

(Vibrio
alginolyticus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLU A 294
LEU A 291
TYR A 287
LEU A 234
 None
 0.99A 4iomA-3mruA:
undetectable		 4iomA-3mruA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2b DIAMINOPIMELATE
DECARBOXYLASE

(Vibrio cholerae) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ALA A 179
GLU A 228
LEU A 225
LEU A 221
 None
 0.90A 4iomA-3n2bA:
2.7		 4iomA-3n2bA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ng0 GLUTAMINE SYNTHETASE

(Synechocystis
sp. PCC 6803) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ALA A 313
GLU A 454
LEU A 418
LEU A 422
 None
 1.01A 4iomA-3ng0A:
2.1		 4iomA-3ng0A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oee ATP SYNTHASE SUBUNIT
ALPHA

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ALA A 449
PRO A 445
LEU A 429
LEU A 455
 None
 0.77A 4iomA-3oeeA:
undetectable		 4iomA-3oeeA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2c PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
ovatus) 		PF06824
(Glyco_hydro_125) 		4 ALA A 417
GLU A 477
LEU A 474
LEU A 470
 None
 1.03A 4iomA-3p2cA:
undetectable		 4iomA-3p2cA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tje FAB E09, HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ALA H  74
GLU H  48
TYR H 100
LEU H  89
 None
EDO  H 246 (-3.5A)
None
None
 1.07A 4iomA-3tjeH:
undetectable		 4iomA-3tjeH:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfc CHROMOSOME-ASSOCIATE
D KINESIN KIF4

(Mus musculus) 		PF00225
(Kinesin) 		4 PRO A 316
LEU A  14
TYR A  51
LEU A 328
 None
 1.07A 4iomA-3zfcA:
undetectable		 4iomA-3zfcA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2o YMDB
PHOSPHODIESTERASE

(Bacillus
subtilis) 		PF13277
(YmdB) 		4 ALA A  89
GLU A 137
LEU A 134
TRP A  70
 None
 1.03A 4iomA-4b2oA:
3.1		 4iomA-4b2oA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 ALA A 261
PRO A 259
LEU A 181
LEU A 268
 None
 0.89A 4iomA-4cbwA:
2.5		 4iomA-4cbwA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efh ACTIN-1

(Acanthamoeba
castellanii) 		PF00022
(Actin) 		4 ALA A 260
PRO A 258
LEU A 180
LEU A 267
 None
 0.82A 4iomA-4efhA:
2.8		 4iomA-4efhA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2t SSFS6

(Streptomyces
sp. SF2575) 		PF00201
(UDPGT)
PF06722
(DUF1205) 		4 ALA A  34
PRO A  52
LEU A  32
LEU A   4
 None
 1.02A 4iomA-4g2tA:
undetectable		 4iomA-4g2tA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4go4 PUTATIVE
GAMMA-HYDROXYMUCONIC
SEMIALDEHYDE
DEHYDROGENASE

(Pseudomonas sp.
WBC-3) 		PF00171
(Aldedh) 		4 ALA A 270
GLU A 319
LEU A 304
TRP A 414
 None
 1.04A 4iomA-4go4A:
2.0		 4iomA-4go4A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpp PROBABLE GLUTAMINE
SYNTHETASE

(Pseudomonas
aeruginosa) 		PF00120
(Gln-synt_C)
PF16952
(Gln-synt_N_2) 		4 ALA A 279
GLU A 423
LEU A 391
LEU A 395
 None
 1.02A 4iomA-4hppA:
undetectable		 4iomA-4hppA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kho UNCHARACTERIZED
PROTEIN SPT16M

(Chaetomium
thermophilum) 		PF08512
(Rtt106)
PF08644
(SPT16) 		4 ALA A 860
PRO A 909
LEU A 862
LEU A 874
 None
 1.02A 4iomA-4khoA:
undetectable		 4iomA-4khoA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l11 AGAP007709-PA

(Anopheles
gambiae) 		PF00027
(cNMP_binding) 		4 ALA A 630
PRO A 632
LEU A 636
LEU A 697
 None
 0.94A 4iomA-4l11A:
undetectable		 4iomA-4l11A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq4 50S RIBOSOMAL
PROTEIN L1

(Methanocaldococcus
jannaschii) 		PF00687
(Ribosomal_L1) 		4 PRO A 130
GLU A  47
LEU A 146
LEU A 142
 None
 0.87A 4iomA-4lq4A:
undetectable		 4iomA-4lq4A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mru SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 ALA A 129
PRO A 127
TYR A  45
LEU A  47
 None
 0.97A 4iomA-4mruA:
undetectable		 4iomA-4mruA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n1a CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 ALA A 800
LEU A 844
LEU A 848
TRP A 794
 None
 1.00A 4iomA-4n1aA:
undetectable		 4iomA-4n1aA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nh0 CELL
DIVISIONFTSK/SPOIIIE

(Thermomonospora
curvata) 		PF01580
(FtsK_SpoIIIE) 		4 ALA A 800
LEU A 844
LEU A 848
TRP A 794
 None
 0.98A 4iomA-4nh0A:
undetectable		 4iomA-4nh0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3z COPN

(Chlamydia
pneumoniae) 		PF07201
(HrpJ) 		4 ALA A 182
PRO A 139
GLU A 106
LEU A 186
 None
 0.93A 4iomA-4p3zA:
3.2		 4iomA-4p3zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfs COBYRINIC ACID
A,C-DIAMIDE SYNTHASE

(Mycolicibacterium
smegmatis) 		PF13614
(AAA_31) 		4 ALA A 188
PRO A 154
LEU A 185
LEU A 213
 None
 0.94A 4iomA-4pfsA:
11.3		 4iomA-4pfsA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl7 ACTIN,THYMOSIN
BETA-4

(Homo sapiens;
Komagataella
phaffii) 		PF00022
(Actin)
PF01290
(Thymosin) 		4 ALA A 260
PRO A 258
LEU A 180
LEU A 267
 None
 0.90A 4iomA-4pl7A:
undetectable		 4iomA-4pl7A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5

(Homo sapiens) 		PF12348
(CLASP_N) 		4 PRO A 945
LEU A 994
LEU A 998
TRP A 968
 None
 1.05A 4iomA-4qmiA:
undetectable		 4iomA-4qmiA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r40 PROTEIN TOLB

(Yersinia pestis) 		PF04052
(TolB_N)
PF07676
(PD40) 		4 ALA A 259
PRO A 249
LEU A 270
LEU A 302
 None
 1.08A 4iomA-4r40A:
undetectable		 4iomA-4r40A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubt ACETYL-COA
ACETYLTRANSFERASE
FADA5

(Mycobacterium
tuberculosis) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ALA A 272
PRO A 270
GLU A   8
LEU A 361
 None
 1.01A 4iomA-4ubtA:
undetectable		 4iomA-4ubtA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoz BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		4 ALA A 579
PRO A 581
LEU A 546
LEU A 549
 None
 0.76A 4iomA-4uozA:
2.0		 4iomA-4uozA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF07678
(A2M_comp) 		4 ALA A1417
GLU A1179
LEU A1423
LEU A1431
 None
 0.98A 4iomA-4ziuA:
undetectable		 4iomA-4ziuA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a42 UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF11974
(MG1) 		4 ALA A1417
GLU A1179
LEU A1423
LEU A1431
 None
 0.99A 4iomA-5a42A:
undetectable		 4iomA-5a42A:
16.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		4 PRO A 384
GLU A 388
LEU A 391
LEU A 407
 None
 0.93A 4iomA-5a5gA:
60.0		 4iomA-5a5gA:
66.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		4 PRO A 384
GLU A 388
LEU A 391
TRP A 411
 None
 0.44A 4iomA-5a5gA:
60.0		 4iomA-5a5gA:
66.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1u METALLO-BETA-LACTAMA
SE

(Serratia
marcescens) 		PF00753
(Lactamase_B) 		4 PRO A 190
GLU A 260
LEU A 257
LEU A 253
 None
 0.83A 4iomA-5b1uA:
undetectable		 4iomA-5b1uA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c41 RIBOKINASE

(Homo sapiens) 		PF00294
(PfkB) 		4 ALA A 181
LEU A 185
TYR A 190
LEU A 206
 None
 1.05A 4iomA-5c41A:
2.2		 4iomA-5c41A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djq CBB3-TYPE CYTOCHROME
C OXIDASE SUBUNIT II

(Pseudomonas
stutzeri) 		PF02433
(FixO) 		4 PRO B  97
LEU B 160
TYR B 167
LEU B  54
 None
 1.04A 4iomA-5djqB:
undetectable		 4iomA-5djqB:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dju NPH1-2
ENGINEERED PROTEIN,
ZDK3 AFFIBODY

(Avena sativa;
Staphylococcus
aureus) 		PF13426
(PAS_9)
PF02216
(B) 		4 ALA A 542
LEU A 408
TYR B  17
LEU A 546
 None
 0.95A 4iomA-5djuA:
undetectable		 4iomA-5djuA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fac ALANINE RACEMASE

(Streptomyces
coelicolor) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ALA A  58
PRO A  56
LEU A  87
LEU A  69
 None
 0.93A 4iomA-5facA:
3.6		 4iomA-5facA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g52 VP3

(Deformed wing
virus) 		PF00073
(Rhv) 		4 ALA C  85
PRO C  87
LEU C  83
LEU C 206
 None
 0.97A 4iomA-5g52C:
undetectable		 4iomA-5g52C:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 ALA A 404
GLU A 369
LEU A 370
LEU A 362
 None
 1.05A 4iomA-5hm5A:
undetectable		 4iomA-5hm5A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5im3 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE

(Pseudomonas
aeruginosa) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 ALA A 908
LEU A 888
TYR A 892
LEU A 906
 None
 0.93A 4iomA-5im3A:
3.0		 4iomA-5im3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ALA A 563
LEU A 398
TYR A 649
LEU A 405
 None
 0.94A 4iomA-5ju6A:
2.4		 4iomA-5ju6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 ALA B 303
PRO B 301
LEU B 291
LEU B 289
 None
 1.07A 4iomA-5l3rB:
11.8		 4iomA-5l3rB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liv CYTOCHROME P450
CYP260A1,CYTOCHROME
P450 CYP260A1

(Sorangium
cellulosum) 		PF00067
(p450) 		4 ALA A 396
PRO A 394
GLU A 317
LEU A 287
 HEM  A 501 ( 3.7A)
None
None
HEM  A 501 ( 4.6A)
 0.88A 4iomA-5livA:
undetectable		 4iomA-5livA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq4 CYAGOX

(Cyanothece sp.
PCC 7425) 		PF00881
(Nitroreductase) 		4 ALA A 193
TYR A 103
LEU A 105
TRP A 112
 None
 0.95A 4iomA-5lq4A:
undetectable		 4iomA-5lq4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lqd ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE

(Streptomyces
venezuelae) 		PF00982
(Glyco_transf_20) 		4 ALA A 170
PRO A 172
TYR A  98
LEU A  93
 None
 1.01A 4iomA-5lqdA:
2.5		 4iomA-5lqdA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6g BETA-GLUCOSIDASE

(Saccharopolyspora
erythraea) 		no annotation 4 ALA A 555
LEU A 415
TYR A 614
LEU A 422
 None
 0.95A 4iomA-5m6gA:
2.2		 4iomA-5m6gA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA
MDCC

(Pseudomonas
aeruginosa;
Pseudomonas
protegens) 		PF16957
(Mal_decarbox_Al)
PF06857
(ACP) 		4 ALA A 524
GLU C  90
LEU C  87
LEU A 239
 None
 0.94A 4iomA-5vj1A:
undetectable		 4iomA-5vj1A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wze AMINOPEPTIDASE P

(Pseudomonas
aeruginosa) 		no annotation 4 ALA A  61
PRO A  59
TYR A  74
LEU A  76
 None
 1.06A 4iomA-5wzeA:
undetectable		 4iomA-5wzeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x89 ENDA-LIKE
PROTEIN,TRNA-SPLICIN
G ENDONUCLEASE

(Methanopyrus
kandleri) 		no annotation 4 ALA A  94
PRO A  90
TYR A 170
LEU A 168
 None
 1.07A 4iomA-5x89A:
undetectable		 4iomA-5x89A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xip PROLYL-TRNA
SYNTHETASE, PUTATIVE

(Eimeria tenella) 		no annotation 4 ALA A 629
PRO A 625
LEU A 562
LEU A 566
 None
 0.99A 4iomA-5xipA:
undetectable		 4iomA-5xipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxg -

(-) 		no annotation 4 ALA A  20
PRO A  23
LEU A  30
LEU A 235
 None
 0.86A 4iomA-5xxgA:
undetectable		 4iomA-5xxgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 ALA A 571
LEU A 392
TYR A 654
LEU A 410
 None
 1.05A 4iomA-5xxoA:
3.8		 4iomA-5xxoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yx2 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3-LIKE

(Homo sapiens) 		no annotation 4 ALA B 320
GLU B 340
LEU B 343
LEU B 288
 None
 1.06A 4iomA-5yx2B:
undetectable		 4iomA-5yx2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zya SPLICING FACTOR 3B
SUBUNIT 1

(Homo sapiens) 		no annotation 4 ALA C 716
PRO C 718
LEU C 680
LEU C 683
 None
 1.06A 4iomA-5zyaC:
undetectable		 4iomA-5zyaC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a2f -

(-) 		no annotation 4 ALA A 315
PRO A 313
LEU A 243
LEU A 240
 None
 0.84A 4iomA-6a2fA:
2.4		 4iomA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c43 GAMMA-AMINOBUTYRALDE
HYDE DEHYDROGENASE

(Salmonella
enterica) 		no annotation 4 ALA A 165
PRO A 138
LEU A 118
LEU A 461
 None
 1.06A 4iomA-6c43A:
undetectable		 4iomA-6c43A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ALA H 416
PRO H 390
LEU H 427
LEU H 397
 None
 1.02A 4iomA-6chsH:
2.2		 4iomA-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ck0 BIOTIN ACETYL
COENZYME A
CARBOXYLASE
SYNTHETASE

(Helicobacter
pylori) 		no annotation 4 ALA A  62
PRO A  31
LEU A  23
LEU A  19
 None
EDO  A 303 (-4.8A)
None
None
 0.86A 4iomA-6ck0A:
undetectable		 4iomA-6ck0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eu2 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC3

(Saccharomyces
cerevisiae) 		no annotation 4 ALA O 504
PRO O 502
GLU O 493
LEU O 540
 None
 0.97A 4iomA-6eu2O:
undetectable		 4iomA-6eu2O:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f85 CYTOCHROME P450
CYP260A1

(Sorangium
cellulosum) 		no annotation 4 ALA A 346
PRO A 344
GLU A 267
LEU A 237
 HEM  A 501 ( 3.7A)
None
None
HEM  A 501 (-3.4A)
 0.86A 4iomA-6f85A:
undetectable		 4iomA-6f85A:
undetectable