SIMILAR PATTERNS OF AMINO ACIDS FOR 4IKJ_A_SUZA201_1

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1bgp	BARLEY GRAIN PEROXIDASE (Hordeum vulgare)	PF00141 (peroxidase)	4	ALA A  41 LEU A  43 SER A 117 SER A 121	HEM  A 400 (-3.5A) None None None	1.03A	4ikjA-1bgpA: undetectable 4ikjB-1bgpA: undetectable	4ikjA-1bgpA: 16.88 4ikjB-1bgpA: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dlp	LECTIN SCAFET PRECURSOR (Hyacinthoides hispanica)	PF01453 (B_lectin)	4	LEU A  62 LEU A  68 SER A  81 THR A  83	None	0.99A	4ikjA-1dlpA: undetectable 4ikjB-1dlpA: undetectable	4ikjA-1dlpA: 18.78 4ikjB-1dlpA: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1e8t	HEMAGGLUTININ-NEURAM INIDASE (Avian avulavirus 1)	PF00423 (HN)	4	LEU A 561 ALA A 546 SER A 529 THR A 527	None	0.69A	4ikjA-1e8tA: undetectable 4ikjB-1e8tA: undetectable	4ikjA-1e8tA: 15.56 4ikjB-1e8tA: 15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1f5j	BETA-1,4-XYLANASE (Dictyoglomus thermophilum)	PF00457 (Glyco_hydro_11)	4	LYS A  19 LEU A  17 ALA A  44 SER A  76	None	0.85A	4ikjA-1f5jA: 0.0 4ikjB-1f5jA: undetectable	4ikjA-1f5jA: 19.39 4ikjB-1f5jA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1f80	HOLO-(ACYL CARRIER PROTEIN) SYNTHASE (Bacillus subtilis)	PF01648 (ACPS)	4	LEU A   7 ALA A 111 SER A 102 THR A 104	None None None NA  A1255 (-3.8A)	0.84A	4ikjA-1f80A: undetectable 4ikjB-1f80A: undetectable	4ikjA-1f80A: 24.24 4ikjB-1f80A: 24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1gd3	CYSTATIN A (Homo sapiens)	PF00031 (Cystatin)	4	LEU A  95 ALA A   9 LEU A   6 SER A   7	None	1.06A	4ikjA-1gd3A: undetectable 4ikjB-1gd3A: undetectable	4ikjA-1gd3A: 23.08 4ikjB-1gd3A: 23.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1gke	TRANSTHYRETIN (Rattus norvegicus)	PF00576 (Transthyretin)	5	LYS A  15 LEU A  17 ALA A 108 LEU A 110 THR A 119	None	0.67A	4ikjA-1gkeA: 21.6 4ikjB-1gkeA: 20.4	4ikjA-1gkeA: 83.33 4ikjB-1gkeA: 83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1guq	GALACTOSE-1-PHOSPHAT E URIDYLYLTRANSFERASE (Escherichia coli)	PF01087 (GalP_UDP_transf) PF02744 (GalP_UDP_tr_C)	4	LEU A 119 ALA A 256 LEU A 122 SER A 123	None	1.04A	4ikjA-1guqA: undetectable 4ikjB-1guqA: undetectable	4ikjA-1guqA: 16.81 4ikjB-1guqA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1h4u	NIDOGEN-1 (Mus musculus)	PF07474 (G2F)	4	LEU A 623 SER A 439 THR A 441 SER A 430	None	0.85A	4ikjA-1h4uA: 0.0 4ikjB-1h4uA: 0.0	4ikjA-1h4uA: 18.80 4ikjB-1h4uA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1j0a	1-AMINOCYCLOPROPANE- 1-CARBOXYLATE DEAMINASE (Pyrococcus horikoshii)	PF00291 (PALP)	4	LEU A  94 ALA A  90 LEU A  96 THR A  87	None	0.92A	4ikjA-1j0aA: undetectable 4ikjB-1j0aA: undetectable	4ikjA-1j0aA: 19.46 4ikjB-1j0aA: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1j1w	ISOCITRATE DEHYDROGENASE (Azotobacter vinelandii)	PF03971 (IDH)	4	LEU A 577 ALA A  78 SER A 573 THR A  75	None	0.99A	4ikjA-1j1wA: undetectable 4ikjB-1j1wA: undetectable	4ikjA-1j1wA: 10.31 4ikjB-1j1wA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1jmy	BILE-SALT-ACTIVATED LIPASE (Homo sapiens)	PF00135 (COesterase)	4	LYS A 361 LEU A 357 ALA A 360 THR A 352	None	1.04A	4ikjA-1jmyA: undetectable 4ikjB-1jmyA: undetectable	4ikjA-1jmyA: 12.64 4ikjB-1jmyA: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1l5j	ACONITATE HYDRATASE 2 (Escherichia coli)	PF00330 (Aconitase) PF06434 (Aconitase_2_N) PF11791 (Aconitase_B_N)	4	LEU A 361 ALA A 357 LEU A 363 THR A 354	None	0.87A	4ikjA-1l5jA: undetectable 4ikjB-1l5jA: undetectable	4ikjA-1l5jA: 8.33 4ikjB-1l5jA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1m9q	ENDOTHELIAL NITRIC-OXIDE SYNTHASE (Homo sapiens)	PF02898 (NO_synthase)	4	LEU A 326 ALA A 324 LEU A 328 SER A 409	None	1.04A	4ikjA-1m9qA: undetectable 4ikjB-1m9qA: undetectable	4ikjA-1m9qA: 15.48 4ikjB-1m9qA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1mk7	TALIN (Gallus gallus)	PF00373 (FERM_M) PF02174 (IRS)	4	ALA B 360 SER B 365 THR B 367 SER B 379	None	0.41A	4ikjA-1mk7B: undetectable 4ikjB-1mk7B: undetectable	4ikjA-1mk7B: 22.49 4ikjB-1mk7B: 22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1nig	HYPOTHETICAL PROTEIN TA1238 (Thermoplasma acidophilum)	PF09155 (DUF1940)	4	ALA A  29 LEU A 102 SER A 105 SER A 109	None	0.93A	4ikjA-1nigA: undetectable 4ikjB-1nigA: undetectable	4ikjA-1nigA: 17.09 4ikjB-1nigA: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1p3w	CYSTEINE DESULFURASE (Escherichia coli)	no annotation	4	LEU B 344 ALA B 341 LEU B 339 SER B 336	None	1.01A	4ikjA-1p3wB: undetectable 4ikjB-1p3wB: undetectable	4ikjA-1p3wB: 15.71 4ikjB-1p3wB: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1p3w	CYSTEINE DESULFURASE (Escherichia coli)	no annotation	4	LEU B 344 ALA B 341 LEU B 339 THR B 102	None	1.03A	4ikjA-1p3wB: undetectable 4ikjB-1p3wB: undetectable	4ikjA-1p3wB: 15.71 4ikjB-1p3wB: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1qgj	PEROXIDASE N (Arabidopsis thaliana)	PF00141 (peroxidase)	4	ALA A  34 LEU A  36 SER A 105 SER A 109	HEM  A1350 (-3.7A) None None None	0.99A	4ikjA-1qgjA: undetectable 4ikjB-1qgjA: undetectable	4ikjA-1qgjA: 20.38 4ikjB-1qgjA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rgw	ZASP PROTEIN (Homo sapiens)	PF00595 (PDZ)	4	ALA A  51 SER A  77 THR A  79 SER A   4	None	0.89A	4ikjA-1rgwA: undetectable 4ikjB-1rgwA: undetectable	4ikjA-1rgwA: 17.42 4ikjB-1rgwA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1sb3	4-HYDROXYBENZOYL-COA REDUCTASE BETA SUBUNIT (Thauera aromatica)	PF00941 (FAD_binding_5) PF03450 (CO_deh_flav_C)	4	LEU B 252 ALA B 240 LEU B 242 SER B 219	None	0.96A	4ikjA-1sb3B: undetectable 4ikjB-1sb3B: undetectable	4ikjA-1sb3B: 16.72 4ikjB-1sb3B: 16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1sn2	TRANSTHYRETIN (Sparus aurata)	PF00576 (Transthyretin)	5	LYS A  15 LEU A  17 ALA A 108 LEU A 110 THR A 119	None	0.64A	4ikjA-1sn2A: 20.4 4ikjB-1sn2A: 20.8	4ikjA-1sn2A: 54.62 4ikjB-1sn2A: 54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1t4n	RIBONUCLEASE III (Saccharomyces cerevisiae)	PF00035 (dsrm)	4	LYS A 443 ALA A 446 LEU A 377 SER A 376	None	0.99A	4ikjA-1t4nA: undetectable 4ikjB-1t4nA: undetectable	4ikjA-1t4nA: 22.88 4ikjB-1t4nA: 22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1tfp	TRANSTHYRETIN (Gallus gallus)	PF00576 (Transthyretin)	6	LYS A  15 LEU A  17 ALA A 108 LEU A 110 SER A 117 THR A 119	None	0.60A	4ikjA-1tfpA: 19.7 4ikjB-1tfpA: 19.1	4ikjA-1tfpA: 73.85 4ikjB-1tfpA: 73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1tvz	3-HYDROXY-3-METHYLGL UTARYL-COA SYNTHASE (Staphylococcus aureus)	PF01154 (HMG_CoA_synt_N) PF08540 (HMG_CoA_synt_C)	4	LYS A   2 ALA A 170 SER A 315 THR A 317	None	0.87A	4ikjA-1tvzA: undetectable 4ikjB-1tvzA: undetectable	4ikjA-1tvzA: 15.95 4ikjB-1tvzA: 15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1u6z	EXOPOLYPHOSPHATASE (Escherichia coli)	PF02541 (Ppx-GppA)	4	LEU A 124 ALA A 122 LEU A 297 SER A 148	None None None SO4  A 701 (-4.2A)	1.03A	4ikjA-1u6zA: undetectable 4ikjB-1u6zA: undetectable	4ikjA-1u6zA: 13.50 4ikjB-1u6zA: 13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1urd	MALTOSE-BINDING PROTEIN (Alicyclobacillus acidocaldarius)	PF01547 (SBP_bac_1)	4	ALA A 301 LEU A 305 THR A 298 SER A 296	None	1.00A	4ikjA-1urdA: undetectable 4ikjB-1urdA: undetectable	4ikjA-1urdA: 16.53 4ikjB-1urdA: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1uun	MSPA (Mycolicibacterium smegmatis)	PF09203 (MspA)	4	LEU A  62 ALA A 164 LEU A 166 THR A 176	None	0.77A	4ikjA-1uunA: 3.0 4ikjB-1uunA: 3.1	4ikjA-1uunA: 22.83 4ikjB-1uunA: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1vch	PHOSPHORIBOSYLTRANSF ERASE-RELATED PROTEIN (Thermus thermophilus)	PF00156 (Pribosyltran)	4	LEU A  45 ALA A  41 LEU A  70 THR A  38	None	1.05A	4ikjA-1vchA: undetectable 4ikjB-1vchA: undetectable	4ikjA-1vchA: 21.14 4ikjB-1vchA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1x7p	RRNA METHYLTRANSFERASE (Streptomyces viridochromogenes)	PF00588 (SpoU_methylase)	4	LEU A 261 ALA A 269 THR A 268 SER A 146	SAM  A 301 (-4.1A) None None None	0.99A	4ikjA-1x7pA: undetectable 4ikjB-1x7pA: undetectable	4ikjA-1x7pA: 16.67 4ikjB-1x7pA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ykd	ADENYLATE CYCLASE (Anabaena sp.)	PF01590 (GAF)	4	LYS A 200 ALA A 101 LEU A 180 THR A 104	None	1.01A	4ikjA-1ykdA: undetectable 4ikjB-1ykdA: undetectable	4ikjA-1ykdA: 15.98 4ikjB-1ykdA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2bnh	RIBONUCLEASE INHIBITOR (Sus scrofa)	PF13516 (LRR_6)	4	LEU A 370 LEU A 395 SER A 394 THR A 365	None	1.03A	4ikjA-2bnhA: undetectable 4ikjB-2bnhA: undetectable	4ikjA-2bnhA: 13.36 4ikjB-2bnhA: 13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2c2i	RV0130 (Mycobacterium tuberculosis)	PF01575 (MaoC_dehydratas)	4	LEU A  91 ALA A 143 THR A 129 SER A 110	None	0.74A	4ikjA-2c2iA: undetectable 4ikjB-2c2iA: undetectable	4ikjA-2c2iA: 23.03 4ikjB-2c2iA: 23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cdp	BETA-AGARASE 1 (Saccharophagus degradans)	PF03422 (CBM_6)	4	ALA A   6 SER A 137 THR A 135 SER A  62	None	0.97A	4ikjA-2cdpA: undetectable 4ikjB-2cdpA: undetectable	4ikjA-2cdpA: 20.61 4ikjB-2cdpA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2csd	TOPOISOMERASE V (Methanopyrus kandleri)	PF13412 (HTH_24) PF14520 (HHH_5)	5	LYS A  28 LEU A 254 LEU A  62 SER A  65 SER A  69	None	1.33A	4ikjA-2csdA: undetectable 4ikjB-2csdA: undetectable	4ikjA-2csdA: 13.15 4ikjB-2csdA: 13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2hr2	HYPOTHETICAL PROTEIN (Chlorobaculum tepidum)	PF12968 (DUF3856)	4	ALA A  82 LEU A  99 SER A 102 SER A 106	None None GOL  A 159 (-2.8A) GOL  A 159 ( 4.4A)	0.93A	4ikjA-2hr2A: undetectable 4ikjB-2hr2A: undetectable	4ikjA-2hr2A: 24.05 4ikjB-2hr2A: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2i6v	GENERAL SECRETION PATHWAY PROTEIN C (Vibrio cholerae)	no annotation	4	LEU A 267 ALA A 263 SER A 289 THR A 291	None	0.94A	4ikjA-2i6vA: undetectable 4ikjB-2i6vA: undetectable	4ikjA-2i6vA: 17.32 4ikjB-2i6vA: 17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2igt	SAM DEPENDENT METHYLTRANSFERASE (Agrobacterium fabrum)	PF10672 (Methyltrans_SAM)	4	LEU A  16 LEU A 282 SER A 301 THR A 251	ACY  A1010 (-4.9A) None None None	0.80A	4ikjA-2igtA: undetectable 4ikjB-2igtA: undetectable	4ikjA-2igtA: 17.95 4ikjB-2igtA: 17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2jis	CYSTEINE SULFINIC ACID DECARBOXYLASE (Homo sapiens)	PF00282 (Pyridoxal_deC)	5	LEU A 201 ALA A 199 LEU A 203 SER A 207 THR A 205	None	1.45A	4ikjA-2jisA: undetectable 4ikjB-2jisA: undetectable	4ikjA-2jisA: 12.97 4ikjB-2jisA: 12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2lpv	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Aedes aegypti)	PF00254 (FKBP_C)	4	LYS A  74 LEU A   8 THR A  28 SER A  39	None	1.06A	4ikjA-2lpvA: undetectable 4ikjB-2lpvA: undetectable	4ikjA-2lpvA: 21.80 4ikjB-2lpvA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2opi	L-FUCULOSE-1-PHOSPHA TE ALDOLASE (Bacteroides thetaiotaomicron)	PF00596 (Aldolase_II)	4	LEU A  92 LEU A  30 SER A  41 SER A  45	None	1.00A	4ikjA-2opiA: undetectable 4ikjB-2opiA: undetectable	4ikjA-2opiA: 19.25 4ikjB-2opiA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2oxf	URIDINE PHOSPHORYLASE (Salmonella enterica)	PF01048 (PNP_UDP_1)	4	ALA A1124 LEU A1121 SER A1120 THR A1204	None	1.05A	4ikjA-2oxfA: undetectable 4ikjB-2oxfA: undetectable	4ikjA-2oxfA: 20.48 4ikjB-2oxfA: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2pfc	HYPOTHETICAL PROTEIN RV0098/MT0107 (Mycobacterium tuberculosis)	PF10862 (FcoT)	4	LEU A 141 LEU A  54 SER A  47 THR A  49	None	0.84A	4ikjA-2pfcA: undetectable 4ikjB-2pfcA: undetectable	4ikjA-2pfcA: 18.85 4ikjB-2pfcA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2pia	PHTHALATE DIOXYGENASE REDUCTASE (Burkholderia cepacia)	PF00111 (Fer2) PF00175 (NAD_binding_1) PF00970 (FAD_binding_6)	4	LEU A 319 LEU A 321 SER A 245 THR A 247	None	0.96A	4ikjA-2piaA: undetectable 4ikjB-2piaA: undetectable	4ikjA-2piaA: 18.04 4ikjB-2piaA: 18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2pq6	UDP-GLUCURONOSYL/UDP -GLUCOSYLTRANSFERASE (Medicago truncatula)	PF00201 (UDPGT)	4	LEU A 237 ALA A 456 SER A 466 THR A 460	None	1.04A	4ikjA-2pq6A: undetectable 4ikjB-2pq6A: undetectable	4ikjA-2pq6A: 14.25 4ikjB-2pq6A: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qp2	UNKNOWN PROTEIN (Photorhabdus laumondii)	PF01823 (MACPF)	4	ALA A 150 SER A 216 THR A 218 SER A 262	None	0.46A	4ikjA-2qp2A: undetectable 4ikjB-2qp2A: undetectable	4ikjA-2qp2A: 13.13 4ikjB-2qp2A: 13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qq6	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME-LIKE PROTEIN (Rubrobacter xylanophilus)	PF02746 (MR_MLE_N) PF13378 (MR_MLE_C)	4	LEU A 236 LEU A 239 THR A 258 SER A 257	None	0.96A	4ikjA-2qq6A: undetectable 4ikjB-2qq6A: undetectable	4ikjA-2qq6A: 15.62 4ikjB-2qq6A: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qx2	SEX PHEROMONE STAPH-CAM373 (Staphylococcus aureus)	PF07537 (CamS)	4	LYS A 325 LEU A 286 SER A 289 THR A 291	None	1.01A	4ikjA-2qx2A: undetectable 4ikjB-2qx2A: undetectable	4ikjA-2qx2A: 16.37 4ikjB-2qx2A: 16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2r6r	CELL DIVISION PROTEIN FTSZ (Aquifex aeolicus)	PF00091 (Tubulin) PF12327 (FtsZ_C)	4	LYS 1  54 ALA 1  38 LEU 1  36 SER 1  98	None	0.91A	4ikjA-2r6r1: undetectable 4ikjB-2r6r1: undetectable	4ikjA-2r6r1: 18.71 4ikjB-2r6r1: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2rjo	TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN (Paraburkholderia phytofirmans)	PF13407 (Peripla_BP_4)	4	LEU A 309 ALA A 147 LEU A 312 SER A 319	None	1.01A	4ikjA-2rjoA: undetectable 4ikjB-2rjoA: undetectable	4ikjA-2rjoA: 18.21 4ikjB-2rjoA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2v8n	LACTOSE PERMEASE (Escherichia coli)	PF01306 (LacY_symp)	4	LEU A 222 LEU A 225 THR A 399 SER A 396	None	1.03A	4ikjA-2v8nA: undetectable 4ikjB-2v8nA: undetectable	4ikjA-2v8nA: 14.46 4ikjB-2v8nA: 14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2v9u	MSPA (Mycolicibacterium smegmatis)	PF09203 (MspA)	4	LEU A  62 ALA A 164 LEU A 166 THR A 176	LEU  A  62 ( 0.5A) ALA  A 164 ( 0.0A) LEU  A 166 ( 0.5A) THR  A 176 ( 0.8A)	0.69A	4ikjA-2v9uA: 3.2 4ikjB-2v9uA: 3.2	4ikjA-2v9uA: 23.88 4ikjB-2v9uA: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2vwb	PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (Methanocaldococcus jannaschii)	PF00814 (Peptidase_M22) PF01163 (RIO1)	4	LYS A 489 ALA A 490 THR A 453 SER A 455	None	0.95A	4ikjA-2vwbA: undetectable 4ikjB-2vwbA: undetectable	4ikjA-2vwbA: 11.80 4ikjB-2vwbA: 11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w0m	SSO2452 (Sulfolobus solfataricus)	PF06745 (ATPase)	4	LEU A 127 ALA A 163 SER A  40 THR A 164	None	1.04A	4ikjA-2w0mA: undetectable 4ikjB-2w0mA: undetectable	4ikjA-2w0mA: 21.84 4ikjB-2w0mA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w6d	DYNAMIN FAMILY PROTEIN (Nostoc punctiforme)	PF00350 (Dynamin_N)	4	LEU A  49 ALA A  38 LEU A  51 THR A  34	None	0.91A	4ikjA-2w6dA: undetectable 4ikjB-2w6dA: undetectable	4ikjA-2w6dA: 12.22 4ikjB-2w6dA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2wua	ACETOACETYL COA THIOLASE (Helianthus annuus)	PF00108 (Thiolase_N) PF02803 (Thiolase_C)	4	LEU A  77 LEU A 163 SER A 102 THR A 131	None	1.04A	4ikjA-2wuaA: undetectable 4ikjB-2wuaA: undetectable	4ikjA-2wuaA: 14.75 4ikjB-2wuaA: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xf2	CATALASE (Penicillium janthinellum)	PF00199 (Catalase) PF06628 (Catalase-rel)	4	LEU A 289 LEU A 290 THR A 436 SER A 434	None	1.03A	4ikjA-2xf2A: undetectable 4ikjB-2xf2A: undetectable	4ikjA-2xf2A: 10.94 4ikjB-2xf2A: 10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xn1	ALPHA-GALACTOSIDASE (Lactobacillus acidophilus)	PF02065 (Melibiase) PF16874 (Glyco_hydro_36C) PF16875 (Glyco_hydro_36N)	4	LEU A 369 ALA A 402 LEU A 414 SER A 473	None	0.95A	4ikjA-2xn1A: undetectable 4ikjB-2xn1A: undetectable	4ikjA-2xn1A: 11.35 4ikjB-2xn1A: 11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2y24	XYLANASE (Dickeya chrysanthemi)	PF02055 (Glyco_hydro_30) PF17189 (Glyco_hydro_30C)	4	ALA A 351 SER A 406 THR A 408 SER A 377	None	0.67A	4ikjA-2y24A: undetectable 4ikjB-2y24A: undetectable	4ikjA-2y24A: 15.79 4ikjB-2y24A: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aib	GLUCOSYLTRANSFERASE- SI (Streptococcus mutans)	PF02324 (Glyco_hydro_70)	4	LYS A 549 LEU A 544 SER A 643 THR A 640	None	1.03A	4ikjA-3aibA: undetectable 4ikjB-3aibA: undetectable	4ikjA-3aibA: 9.52 4ikjB-3aibA: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3d1r	FRUCTOSE-1,6-BISPHOS PHATASE CLASS II GLPX (Escherichia coli)	PF03320 (FBPase_glpX)	4	ALA A 102 LEU A 104 SER A 281 THR A 283	None	0.62A	4ikjA-3d1rA: undetectable 4ikjB-3d1rA: undetectable	4ikjA-3d1rA: 16.17 4ikjB-3d1rA: 16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3e0l	GUANINE DEAMINASE (Homo sapiens)	PF01979 (Amidohydro_1)	4	LEU A 338 ALA A 340 SER A 334 THR A 327	None	1.06A	4ikjA-3e0lA: undetectable 4ikjB-3e0lA: undetectable	4ikjA-3e0lA: 15.84 4ikjB-3e0lA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ea0	ATPASE, PARA FAMILY (Chlorobaculum tepidum)	PF13614 (AAA_31)	4	ALA A 223 LEU A 220 SER A 218 SER A 212	None	1.02A	4ikjA-3ea0A: undetectable 4ikjB-3ea0A: undetectable	4ikjA-3ea0A: 21.07 4ikjB-3ea0A: 21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3fc8	TRANSTHYRETIN (Homo sapiens)	PF00576 (Transthyretin)	5	LYS A  15 LEU A  17 ALA A 108 LEU A 110 THR A 119	IFA  A3000 (-3.0A) IFA  A3000 ( 4.7A) IFA  A3000 (-3.1A) IFA  A3000 (-4.1A) IFA  A3000 ( 4.9A)	0.63A	4ikjA-3fc8A: 23.6 4ikjB-3fc8A: 22.6	4ikjA-3fc8A: 100.00 4ikjB-3fc8A: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3g9w	TALIN-2 (Mus musculus)	PF00373 (FERM_M) PF02174 (IRS)	4	ALA A 363 SER A 368 THR A 370 SER A 382	None	0.69A	4ikjA-3g9wA: undetectable 4ikjB-3g9wA: undetectable	4ikjA-3g9wA: 20.48 4ikjB-3g9wA: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gi8	UNCHARACTERIZED PROTEIN MJ0609 (Methanocaldococcus jannaschii)	PF13520 (AA_permease_2)	4	ALA C 296 LEU C  93 SER C  96 SER C 100	None	1.05A	4ikjA-3gi8C: undetectable 4ikjB-3gi8C: undetectable	4ikjA-3gi8C: 18.36 4ikjB-3gi8C: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gnn	NICOTINATE-NUCLEOTID E PYROPHOSPHORYLASE (Burkholderia pseudomallei)	PF01729 (QRPTase_C) PF02749 (QRPTase_N)	4	LEU A 118 LEU A 121 SER A 125 THR A 286	None	1.03A	4ikjA-3gnnA: undetectable 4ikjB-3gnnA: undetectable	4ikjA-3gnnA: 18.15 4ikjB-3gnnA: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hlz	UNCHARACTERIZED PROTEIN BT_1490 (Bacteroides thetaiotaomicron)	PF12712 (DUF3805) PF12713 (DUF3806)	4	LEU A  32 SER A 110 THR A 112 SER A  95	None	0.88A	4ikjA-3hlzA: undetectable 4ikjB-3hlzA: undetectable	4ikjA-3hlzA: 18.39 4ikjB-3hlzA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hri	HISTIDYL-TRNA SYNTHETASE (Trypanosoma brucei)	PF03129 (HGTP_anticodon) PF13393 (tRNA-synt_His)	4	ALA A 353 LEU A 345 SER A 350 THR A 352	None	0.96A	4ikjA-3hriA: undetectable 4ikjB-3hriA: undetectable	4ikjA-3hriA: 14.45 4ikjB-3hriA: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3i1a	SPECTINOMYCIN PHOSPHOTRANSFERASE (Legionella pneumophila)	PF01636 (APH)	4	LYS A 311 LEU A 307 LEU A 170 SER A 176	None	0.97A	4ikjA-3i1aA: undetectable 4ikjB-3i1aA: undetectable	4ikjA-3i1aA: 16.50 4ikjB-3i1aA: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3i44	ALDEHYDE DEHYDROGENASE (Bartonella henselae)	PF00171 (Aldedh)	4	LEU A 173 LEU A 146 SER A 224 THR A 226	None	0.84A	4ikjA-3i44A: undetectable 4ikjB-3i44A: undetectable	4ikjA-3i44A: 13.77 4ikjB-3i44A: 13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ijt	PUTATIVE UNCHARACTERIZED PROTEIN (Streptococcus mutans)	no annotation	4	LEU A  74 LEU A  83 SER A 103 SER A   0	None	0.98A	4ikjA-3ijtA: undetectable 4ikjB-3ijtA: undetectable	4ikjA-3ijtA: 21.95 4ikjB-3ijtA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ivf	TALIN-1 (Mus musculus)	PF00373 (FERM_M) PF02174 (IRS) PF09379 (FERM_N) PF16511 (FERM_f0)	4	ALA A 360 SER A 365 THR A 367 SER A 379	None	0.73A	4ikjA-3ivfA: undetectable 4ikjB-3ivfA: undetectable	4ikjA-3ivfA: 15.01 4ikjB-3ivfA: 15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3iwk	AMINOALDEHYDE DEHYDROGENASE (Pisum sativum)	PF00171 (Aldedh)	4	LEU A 184 LEU A 157 SER A 235 THR A 237	None	0.97A	4ikjA-3iwkA: undetectable 4ikjB-3iwkA: undetectable	4ikjA-3iwkA: 13.12 4ikjB-3iwkA: 13.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3iwu	5-HYDROXYISOURATE HYDROLASE (Danio rerio)	PF00576 (Transthyretin)	4	LEU A  14 LEU A 107 SER A 114 THR A 116	None	0.75A	4ikjA-3iwuA: 19.5 4ikjB-3iwuA: 19.6	4ikjA-3iwuA: 32.86 4ikjB-3iwuA: 32.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3k96	GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+] (Coxiella burnetii)	PF01210 (NAD_Gly3P_dh_N) PF07479 (NAD_Gly3P_dh_C)	4	LEU A 324 ALA A 198 SER A 202 THR A 199	None	1.02A	4ikjA-3k96A: undetectable 4ikjB-3k96A: undetectable	4ikjA-3k96A: 14.70 4ikjB-3k96A: 14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3kq5	HYPOTHETICAL CYTOSOLIC PROTEIN (Coxiella burnetii)	PF07515 (TraI_2_C)	4	LEU A 257 ALA A 253 THR A 250 SER A 247	None	1.04A	4ikjA-3kq5A: undetectable 4ikjB-3kq5A: undetectable	4ikjA-3kq5A: 13.45 4ikjB-3kq5A: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3l7y	PUTATIVE UNCHARACTERIZED PROTEIN SMU.1108C (Streptococcus mutans)	PF08282 (Hydrolase_3)	4	LEU A 134 ALA A 106 SER A 108 THR A 152	None	1.06A	4ikjA-3l7yA: undetectable 4ikjB-3l7yA: undetectable	4ikjA-3l7yA: 19.44 4ikjB-3l7yA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m7d	TOPOISOMERASE V (Methanopyrus kandleri)	PF13412 (HTH_24)	5	LYS A  28 LEU A 254 LEU A  62 SER A  65 SER A  69	None	1.27A	4ikjA-3m7dA: undetectable 4ikjB-3m7dA: undetectable	4ikjA-3m7dA: 16.99 4ikjB-3m7dA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mbe	MHC CLASS II H2-IAG7 BETA CHAIN (Mus musculus)	PF00969 (MHC_II_beta) PF07654 (C1-set)	4	LEU B  26 ALA B  78 LEU B  75 THR B  77	None	1.01A	4ikjA-3mbeB: undetectable 4ikjB-3mbeB: 2.6	4ikjA-3mbeB: 17.62 4ikjB-3mbeB: 17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mmt	FRUCTOSE-BISPHOSPHAT E ALDOLASE (Bartonella henselae)	PF00274 (Glycolytic)	4	LYS A 223 ALA A 261 LEU A  12 THR A 290	2FP  A 350 (-2.2A) None None None	1.00A	4ikjA-3mmtA: undetectable 4ikjB-3mmtA: undetectable	4ikjA-3mmtA: 15.70 4ikjB-3mmtA: 15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3nsj	PERFORIN-1 (Mus musculus)	PF00168 (C2) PF01823 (MACPF)	4	ALA A 106 SER A 170 THR A 172 SER A 233	None	0.52A	4ikjA-3nsjA: 3.3 4ikjB-3nsjA: undetectable	4ikjA-3nsjA: 14.56 4ikjB-3nsjA: 14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3nuu	PKB-LIKE (Homo sapiens)	PF00069 (Pkinase)	4	LYS A 111 LEU A 113 LEU A 155 THR A 148	SO4  A   5 (-2.8A) None None SO4  A 369 (-3.7A)	0.75A	4ikjA-3nuuA: undetectable 4ikjB-3nuuA: undetectable	4ikjA-3nuuA: 18.88 4ikjB-3nuuA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3oks	4-AMINOBUTYRATE TRANSAMINASE (Mycolicibacterium smegmatis)	PF00202 (Aminotran_3)	4	LYS A 209 LEU A 206 ALA A 208 SER A 188	None	0.99A	4ikjA-3oksA: undetectable 4ikjB-3oksA: undetectable	4ikjA-3oksA: 14.16 4ikjB-3oksA: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pei	CYTOSOL AMINOPEPTIDASE (Francisella tularensis)	PF00883 (Peptidase_M17) PF02789 (Peptidase_M17_N)	4	LEU A 290 ALA A 286 LEU A 292 THR A 283	EDO  A 491 (-4.2A) None None None	1.00A	4ikjA-3peiA: undetectable 4ikjB-3peiA: undetectable	4ikjA-3peiA: 13.07 4ikjB-3peiA: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3phf	ENVELOPE GLYCOPROTEIN H (Human gammaherpesvirus 4)	no annotation	4	LEU A 351 ALA A 104 LEU A 348 SER A 345	None	0.86A	4ikjA-3phfA: undetectable 4ikjB-3phfA: undetectable	4ikjA-3phfA: 11.95 4ikjB-3phfA: 11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3prx	COBRA VENOM FACTOR (Naja kaouthia)	PF00207 (A2M) PF01759 (NTR) PF01821 (ANATO) PF01835 (A2M_N) PF07677 (A2M_recep) PF07678 (A2M_comp) PF07703 (A2M_N_2) PF10569 (Thiol-ester_cl)	4	LEU B 280 LEU B 264 SER B 317 THR B 319	None	0.84A	4ikjA-3prxB: 3.5 4ikjB-3prxB: 3.6	4ikjA-3prxB: 6.13 4ikjB-3prxB: 6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3rc3	ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL (Homo sapiens)	PF00271 (Helicase_C) PF12513 (SUV3_C)	4	LEU A 235 ALA A 237 LEU A 233 THR A 275	None	0.91A	4ikjA-3rc3A: undetectable 4ikjB-3rc3A: undetectable	4ikjA-3rc3A: 12.70 4ikjB-3rc3A: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3s3t	NUCLEOTIDE-BINDING PROTEIN, UNIVERSAL STRESS PROTEIN USPA FAMILY (Lactobacillus plantarum)	PF00582 (Usp)	4	LEU A  36 ALA A  83 LEU A  86 THR A  81	None	0.98A	4ikjA-3s3tA: undetectable 4ikjB-3s3tA: undetectable	4ikjA-3s3tA: 22.44 4ikjB-3s3tA: 22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3s6j	HYDROLASE, HALOACID DEHALOGENASE-LIKE FAMILY (Pseudomonas syringae group genomosp. 3)	PF13419 (HAD_2)	5	LEU A 231 ALA A 228 LEU A 226 THR A 119 SER A 121	None	1.50A	4ikjA-3s6jA: undetectable 4ikjB-3s6jA: undetectable	4ikjA-3s6jA: 19.47 4ikjB-3s6jA: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3sag	EXOSOME COMPONENT 10 (Homo sapiens)	PF00570 (HRDC) PF01612 (DNA_pol_A_exo1)	4	LEU A 396 ALA A 392 LEU A 398 THR A 389	LEU  A 396 ( 0.6A) ALA  A 392 ( 0.0A) LEU  A 398 ( 0.6A) THR  A 389 ( 0.8A)	0.96A	4ikjA-3sagA: undetectable 4ikjB-3sagA: undetectable	4ikjA-3sagA: 14.59 4ikjB-3sagA: 14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3t6s	CERJ (Streptomyces tendae)	PF08541 (ACP_syn_III_C) PF08545 (ACP_syn_III)	4	LEU A 240 ALA A 243 LEU A 239 THR A 187	None	0.94A	4ikjA-3t6sA: undetectable 4ikjB-3t6sA: undetectable	4ikjA-3t6sA: 16.48 4ikjB-3t6sA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tsr	RIBONUCLEASE INHIBITOR (Mus musculus)	PF13516 (LRR_6)	4	LEU E 370 LEU E 395 SER E 394 THR E 365	None	1.02A	4ikjA-3tsrE: undetectable 4ikjB-3tsrE: undetectable	4ikjA-3tsrE: 15.23 4ikjB-3tsrE: 15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ttf	TRANSCRIPTIONAL REGULATORY PROTEIN (Escherichia coli)	PF01300 (Sua5_yciO_yrdC) PF07503 (zf-HYPF)	4	LEU A 484 ALA A 498 SER A 695 THR A 500	None	0.97A	4ikjA-3ttfA: undetectable 4ikjB-3ttfA: undetectable	4ikjA-3ttfA: 10.81 4ikjB-3ttfA: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ty1	HYPOTHETICAL ALDOSE 1-EPIMERASE (Klebsiella pneumoniae)	PF14486 (DUF4432)	4	LYS A 184 LEU A 182 LEU A 196 SER A 360	None	0.81A	4ikjA-3ty1A: undetectable 4ikjB-3ty1A: undetectable	4ikjA-3ty1A: 17.45 4ikjB-3ty1A: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ty1	HYPOTHETICAL ALDOSE 1-EPIMERASE (Klebsiella pneumoniae)	PF14486 (DUF4432)	4	LYS A 184 LEU A 196 THR A 215 SER A 360	None	0.44A	4ikjA-3ty1A: undetectable 4ikjB-3ty1A: undetectable	4ikjA-3ty1A: 17.45 4ikjB-3ty1A: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ty7	PUTATIVE ALDEHYDE DEHYDROGENASE SAV2122 (Staphylococcus aureus)	PF00171 (Aldedh)	4	LEU A 169 LEU A 142 SER A 220 THR A 222	None	0.79A	4ikjA-3ty7A: undetectable 4ikjB-3ty7A: undetectable	4ikjA-3ty7A: 14.22 4ikjB-3ty7A: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3uk2	PANTOTHENATE SYNTHETASE (Burkholderia thailandensis)	PF02569 (Pantoate_ligase)	4	LEU A 268 ALA A 266 LEU A 273 THR A 264	None	1.00A	4ikjA-3uk2A: undetectable 4ikjB-3uk2A: undetectable	4ikjA-3uk2A: 18.44 4ikjB-3uk2A: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3uyj	LYSINE-SPECIFIC DEMETHYLASE 8 (Homo sapiens)	PF13621 (Cupin_8)	4	LEU A 392 LEU A 329 SER A 410 SER A 408	None AKG  A 601 ( 4.4A) AKG  A 601 ( 4.7A) None	0.95A	4ikjA-3uyjA: undetectable 4ikjB-3uyjA: undetectable	4ikjA-3uyjA: 18.55 4ikjB-3uyjA: 18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3vot	L-AMINO ACID LIGASE, BL00235 (Bacillus licheniformis)	PF13535 (ATP-grasp_4)	4	LEU A  97 ALA A  93 LEU A  99 THR A  90	None	0.97A	4ikjA-3votA: undetectable 4ikjB-3votA: undetectable	4ikjA-3votA: 14.52 4ikjB-3votA: 14.52