SIMILAR PATTERNS OF AMINO ACIDS FOR 4IK7_B_IMNB201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9h PROTEIN
(3-AMINO-5-HYDROXYBE
NZOIC ACID SYNTHASE)

(Amycolatopsis
mediterranei) 		PF01041
(DegT_DnrJ_EryC1) 		4 THR A 102
ALA A 100
THR A  79
VAL A  81
 None
 0.77A 4ik7B-1b9hA:
undetectable		 4ik7B-1b9hA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxt PROTEIN
(STREPTOCOCCAL
SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 LEU A 211
THR A 107
THR A  66
VAL A  64
 None
 0.82A 4ik7B-1bxtA:
0.1		 4ik7B-1bxtA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1du5 ZEAMATIN

(Zea mays) 		PF00314
(Thaumatin) 		4 THR A  35
SER A  31
THR A   4
VAL A   2
 None
 0.86A 4ik7B-1du5A:
1.3		 4ik7B-1du5A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE

(Bacillus
subtilis) 		PF01648
(ACPS) 		4 LEU A   7
ALA A 111
SER A 102
THR A 104
 None
None
None
NA  A1255 (-3.8A)
 0.78A 4ik7B-1f80A:
undetectable		 4ik7B-1f80A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fi4 MEVALONATE
5-DIPHOSPHATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00288
(GHMP_kinases_N) 		4 ALA A  51
SER A   7
THR A   5
VAL A   3
 None
 0.54A 4ik7B-1fi4A:
0.0		 4ik7B-1fi4A:
15.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		6 LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.51A 4ik7B-1gkeA:
20.4		 4ik7B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		5 LYS A  15
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.59A 4ik7B-1gkeA:
20.4		 4ik7B-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqs ISOCITRATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00180
(Iso_dh) 		4 THR A 305
SER A 215
THR A 217
VAL A 219
 None
 0.63A 4ik7B-1hqsA:
undetectable		 4ik7B-1hqsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jg5 GTP CYCLOHYDROLASE I
FEEDBACK REGULATORY
PROTEIN

(Rattus
norvegicus) 		PF06399
(GFRP) 		5 LEU A   4
THR A  75
SER A  68
THR A  70
VAL A  72
 None
 1.00A 4ik7B-1jg5A:
undetectable		 4ik7B-1jg5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmy BILE-SALT-ACTIVATED
LIPASE

(Homo sapiens) 		PF00135
(COesterase) 		4 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.82A 4ik7B-1jmyA:
undetectable		 4ik7B-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 LEU A 264
LEU A 268
SER A 271
VAL A 312
 None
 0.77A 4ik7B-1pgsA:
undetectable		 4ik7B-1pgsA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgw BEAN POD MOTTLE
VIRUS LARGE (L)
SUBUNIT

(Bean pod mottle
virus) 		PF02247
(Como_LCP) 		4 THR 2 124
ALA 2 122
THR 2  77
VAL 2  75
 None
 0.75A 4ik7B-1pgw2:
undetectable		 4ik7B-1pgw2:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz8 FAB 17B HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ALA B  93
SER B  33
THR B  35
VAL B  37
 None
 0.46A 4ik7B-1rz8B:
undetectable		 4ik7B-1rz8B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE BETA
SUBUNIT

(Thauera
aromatica) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 LEU B 252
ALA B 240
LEU B 242
SER B 219
 None
 0.82A 4ik7B-1sb3B:
undetectable		 4ik7B-1sb3B:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.85A 4ik7B-1skyB:
undetectable		 4ik7B-1skyB:
17.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.31A 4ik7B-1sn2A:
21.1		 4ik7B-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
LEU A 110
THR A 119
VAL A 121
 None
 0.44A 4ik7B-1sn2A:
21.1		 4ik7B-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		7 LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.48A 4ik7B-1tfpA:
19.1		 4ik7B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.50A 4ik7B-1tfpA:
19.1		 4ik7B-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlc 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermotoga
maritima) 		PF00180
(Iso_dh) 		4 LEU A 130
THR A 237
THR A 183
VAL A 185
 None
 0.73A 4ik7B-1vlcA:
undetectable		 4ik7B-1vlcA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		5 THR J 336
ALA J 334
SER J 332
THR J 207
VAL J 205
 None
 0.79A 4ik7B-1wcdJ:
undetectable		 4ik7B-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 THR J 364
ALA J 366
SER J 105
THR J 107
 None
 0.61A 4ik7B-1wcdJ:
undetectable		 4ik7B-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhl SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY MEMBER
(5L265), PUTATIVE
TROPINONE
REDUCTASE-II

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 LEU A  90
THR A  36
SER A   8
VAL A  63
 None
 0.74A 4ik7B-1xhlA:
undetectable		 4ik7B-1xhlA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 3

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 LEU A 281
THR A 272
LEU A 276
VAL A 220
 None
 0.64A 4ik7B-1y8pA:
undetectable		 4ik7B-1y8pA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bhm TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 ALA A 181
SER A 162
THR A 164
VAL A 166
 None
 0.78A 4ik7B-2bhmA:
undetectable		 4ik7B-2bhmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2i RV0130

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas) 		4 LEU A  91
ALA A 143
THR A 129
VAL A 131
 None
 0.56A 4ik7B-2c2iA:
undetectable		 4ik7B-2c2iA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2

(Mus musculus) 		PF00076
(RRM_1)
PF07078
(FYTT) 		4 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.81A 4ik7B-2f3jA:
undetectable		 4ik7B-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ice COMPLEMENT C3 BETA
CHAIN

(Homo sapiens) 		PF01835
(A2M_N)
PF07703
(A2M_N_2) 		4 LEU A 266
THR A 246
SER A 305
THR A 307
 None
 0.73A 4ik7B-2iceA:
undetectable		 4ik7B-2iceA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4q THIOREDOXIN

(Mycobacterium
tuberculosis) 		PF00085
(Thioredoxin) 		4 THR A  59
ALA A  61
LEU A  63
VAL A  28
 None
 0.83A 4ik7B-2l4qA:
undetectable		 4ik7B-2l4qA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C

(Escherichia
coli) 		PF05175
(MTS)
PF08468
(MTS_N) 		4 THR A 239
ALA A 235
THR A 171
VAL A 169
 None
 0.82A 4ik7B-2pjdA:
undetectable		 4ik7B-2pjdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9u MSPA

(Mycolicibacterium
smegmatis) 		PF09203
(MspA) 		4 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.71A 4ik7B-2v9uA:
3.2		 4ik7B-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blw ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 LEU A 125
THR A 235
THR A 179
VAL A 181
 None
 0.69A 4ik7B-3blwA:
undetectable		 4ik7B-3blwA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvm ENTEROTOXIN TYPE C-3

(Staphylococcus
aureus) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 LEU A 214
THR A 109
THR A  66
VAL A  64
 None
 0.78A 4ik7B-3bvmA:
undetectable		 4ik7B-3bvmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxp PUTATIVE
LIPASE/ESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.76A 4ik7B-3bxpA:
undetectable		 4ik7B-3bxpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4n UNCHARACTERIZED
PROTEIN DR_0571

(Deinococcus
radiodurans) 		PF01266
(DAO) 		4 THR A 168
ALA A 166
THR A  87
VAL A  85
 None
 0.73A 4ik7B-3c4nA:
undetectable		 4ik7B-3c4nA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT
ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh)
PF03063
(Prismane) 		4 ALA G 127
LEU G 125
THR A  70
VAL A  68
 ACY  A 821 (-3.6A)
PEG  G 173 ( 4.0A)
None
ACY  A 821 ( 4.3A)
 0.62A 4ik7B-3cf4G:
undetectable		 4ik7B-3cf4G:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7l LIN1944 PROTEIN

(Listeria
innocua) 		PF13561
(adh_short_C2) 		4 LEU A   5
THR A 110
THR A 108
VAL A 152
 None
 0.72A 4ik7B-3d7lA:
undetectable		 4ik7B-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dms ISOCITRATE
DEHYDROGENASE [NADP]

(Burkholderia
pseudomallei) 		PF00180
(Iso_dh) 		4 THR A 303
SER A 226
THR A 228
VAL A 230
 None
 0.59A 4ik7B-3dmsA:
undetectable		 4ik7B-3dmsA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0g LEUKEMIA INHIBITORY
FACTOR RECEPTOR

(Homo sapiens) 		PF00041
(fn3) 		4 THR A 358
SER A 317
THR A 319
VAL A 321
 NAG  A 484 (-3.0A)
None
None
None
 0.40A 4ik7B-3e0gA:
undetectable		 4ik7B-3e0gA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f5o THIOESTERASE
SUPERFAMILY MEMBER 2

(Homo sapiens) 		PF03061
(4HBT) 		4 LYS A 136
THR A 116
ALA A 114
VAL A 106
 UOC  A 149 (-3.1A)
None
None
None
 0.86A 4ik7B-3f5oA:
undetectable		 4ik7B-3f5oA:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-4.9A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
IFA  A3000 ( 4.9A)
None
 0.75A 4ik7B-3fc8A:
22.7		 4ik7B-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd5 ORNITHINE
CARBAMOYLTRANSFERASE

(Gloeobacter
violaceus) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		5 LYS A 179
LEU A 175
THR A 209
ALA A 178
LEU A 174
 None
 1.19A 4ik7B-3gd5A:
undetectable		 4ik7B-3gd5A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ge2 LIPOPROTEIN,
PUTATIVE

(Streptococcus
pneumoniae) 		PF12182
(DUF3642) 		4 THR A  96
LEU A 100
THR A  87
VAL A  89
 None
 0.63A 4ik7B-3ge2A:
undetectable		 4ik7B-3ge2A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i44 ALDEHYDE
DEHYDROGENASE

(Bartonella
henselae) 		PF00171
(Aldedh) 		4 LEU A 173
LEU A 146
SER A 224
THR A 226
 None
 0.83A 4ik7B-3i44A:
undetectable		 4ik7B-3i44A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kpt COLLAGEN ADHESION
PROTEIN

(Bacillus cereus) 		no annotation 4 LYS A 507
THR A 416
SER A 461
VAL A 457
 None
 0.69A 4ik7B-3kptA:
9.2		 4ik7B-3kptA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mk3 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Salmonella
enterica) 		no annotation 4 THR A  18
ALA A  16
THR A  50
VAL A  52
 None
 0.54A 4ik7B-3mk3A:
undetectable		 4ik7B-3mk3A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmq DECAHEME CYTOCHROME
C MTRF

(Shewanella
oneidensis) 		no annotation 4 THR A 579
LEU A 573
THR A 577
VAL A 605
 None
 0.69A 4ik7B-3pmqA:
undetectable		 4ik7B-3pmqA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prx COBRA VENOM FACTOR

(Naja kaouthia) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LEU B 280
LEU B 264
SER B 317
THR B 319
 None
 0.82A 4ik7B-3prxB:
3.5		 4ik7B-3prxB:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5b TETRAHYDRODIPICOLINA
TE
N-SUCCINYLETRANSFERA
SE

(Pseudomonas
aeruginosa) 		PF14602
(Hexapep_2)
PF14789
(THDPS_M)
PF14790
(THDPS_N) 		4 THR A  55
ALA A  53
THR A  92
VAL A  90
 None
 0.86A 4ik7B-3r5bA:
undetectable		 4ik7B-3r5bA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		4 LEU A 264
ALA A 260
LEU A 266
VAL A 248
 None
 0.82A 4ik7B-3si9A:
undetectable		 4ik7B-3si9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6s CERJ

(Streptomyces
tendae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.82A 4ik7B-3t6sA:
undetectable		 4ik7B-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE

(Klebsiella
pneumoniae) 		PF14486
(DUF4432) 		4 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.76A 4ik7B-3ty1A:
undetectable		 4ik7B-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty7 PUTATIVE ALDEHYDE
DEHYDROGENASE
SAV2122

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 LEU A 169
LEU A 142
SER A 220
THR A 222
 None
 0.74A 4ik7B-3ty7A:
undetectable		 4ik7B-3ty7A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akz TYPE IV SECRETION
SYSTEM PROTEIN VIRB8

(Brucella suis) 		PF04335
(VirB8) 		4 ALA A 181
SER A 162
THR A 164
VAL A 166
 None
 0.82A 4ik7B-4akzA:
undetectable		 4ik7B-4akzA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
BETA

(Methanothermobacter
marburgensis) 		PF04422
(FrhB_FdhB_N)
PF04432
(FrhB_FdhB_C) 		4 LEU C 128
THR C 207
THR C 221
VAL C 219
 None
FAD  C1283 (-4.6A)
None
None
 0.57A 4ik7B-4ci0C:
undetectable		 4ik7B-4ci0C:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dsq PEROXIREDOXIN TYPE-2

(Saccharomyces
cerevisiae) 		PF08534
(Redoxin) 		4 THR A  52
ALA A  54
THR A  90
VAL A  88
 None
 0.63A 4ik7B-4dsqA:
undetectable		 4ik7B-4dsqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es1 BH0342 PROTEIN

(Bacillus
halodurans) 		PF09827
(CRISPR_Cas2) 		4 LEU A  71
THR A   6
LEU A   2
VAL A  38
 None
 0.72A 4ik7B-4es1A:
undetectable		 4ik7B-4es1A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fln PROTEASE DO-LIKE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 THR A 235
ALA A 261
SER A 240
VAL A 222
 None
 0.83A 4ik7B-4flnA:
undetectable		 4ik7B-4flnA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2n D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE,
NAD-BINDING

(Polaromonas sp.
JS666) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 THR A  76
ALA A  78
LEU A  80
VAL A  53
 None
 0.60A 4ik7B-4g2nA:
undetectable		 4ik7B-4g2nA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hc6 HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE

(Mycobacterium
tuberculosis) 		PF01648
(ACPS) 		4 THR A 120
ALA A 122
SER A 113
THR A 115
 None
None
CL  A 202 (-3.1A)
None
 0.78A 4ik7B-4hc6A:
undetectable		 4ik7B-4hc6A:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4il7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Sulfolobus
turreted
icosahedral
virus 1) 		no annotation 4 ALA A 215
LEU A 217
SER A 165
THR A 167
 None
 0.63A 4ik7B-4il7A:
undetectable		 4ik7B-4il7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ki3 OUTER-MEMBRANE
LIPOPROTEIN CARRIER
PROTEIN

(Yersinia pestis) 		PF03548
(LolA) 		4 ALA A 149
SER A 160
THR A 162
VAL A 164
 None
 0.52A 4ik7B-4ki3A:
undetectable		 4ik7B-4ki3A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knc ALGINATE
BIOSYNTHESIS PROTEIN
ALGX

(Pseudomonas
aeruginosa) 		no annotation 4 LEU B 107
THR B 192
LEU B 320
VAL B 189
 None
 0.86A 4ik7B-4kncB:
undetectable		 4ik7B-4kncB:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 LEU A  86
ALA A  41
THR A  11
VAL A   9
 None
 0.74A 4ik7B-4l1yA:
undetectable		 4ik7B-4l1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lj2 CHORISMATE SYNTHASE

(Acinetobacter
baumannii) 		PF01264
(Chorismate_synt) 		4 ALA A  25
LEU A  23
THR A  14
VAL A  12
 None
 0.63A 4ik7B-4lj2A:
undetectable		 4ik7B-4lj2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0e MAF-LIKE PROTEIN
YHDE

(Escherichia
coli) 		PF02545
(Maf) 		4 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.79A 4ik7B-4p0eA:
undetectable		 4ik7B-4p0eA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj1 60 KDA HEAT SHOCK
PROTEIN,
MITOCHONDRIAL

(Homo sapiens) 		PF00118
(Cpn60_TCP1) 		4 LEU A 370
THR A 296
LEU A 373
VAL A 321
 None
 0.75A 4ik7B-4pj1A:
undetectable		 4ik7B-4pj1A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE

(Thermococcus
kodakarensis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 THR A 835
ALA A 832
LEU A 828
THR A 831
 None
 0.83A 4ik7B-4qiwA:
undetectable		 4ik7B-4qiwA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qti UROKINASE
PLASMINOGEN
ACTIVATOR SURFACE
RECEPTOR

(Homo sapiens) 		PF00021
(UPAR_LY6) 		4 THR U  26
SER U  65
THR U  67
VAL U  69
 None
 0.52A 4ik7B-4qtiU:
undetectable		 4ik7B-4qtiU:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.60A 4ik7B-4rjkA:
undetectable		 4ik7B-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uie SURFACE LAYER
PROTEIN

(Geobacillus
stearothermophilus) 		no annotation 4 LEU A 891
THR A 903
THR A 949
VAL A 951
 None
 0.80A 4ik7B-4uieA:
undetectable		 4ik7B-4uieA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb6 PROBABLE
ADENYLYL-SULFATE
KINASE

(Synechocystis
sp. PCC 6803) 		PF01583
(APS_kinase) 		4 LEU A  72
THR A  98
LEU A  73
VAL A  95
 None
 0.78A 4ik7B-5cb6A:
undetectable		 4ik7B-5cb6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyb LIPOPROTEIN

(Streptococcus
pneumoniae) 		PF12182
(DUF3642) 		4 THR A  95
LEU A  99
THR A  86
VAL A  88
 None
 0.70A 4ik7B-5cybA:
undetectable		 4ik7B-5cybA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7c ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 LEU A  69
THR A  79
LEU A  83
VAL A 285
 None
 0.86A 4ik7B-5f7cA:
undetectable		 4ik7B-5f7cA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fub PROTEIN ARGININE
METHYLTRANSFERASE 2

(Danio rerio) 		PF13649
(Methyltransf_25) 		4 THR A 318
SER A 322
THR A 226
VAL A 228
 None
EDO  A1414 ( 4.3A)
EDO  A1414 ( 3.9A)
None
 0.72A 4ik7B-5fubA:
undetectable		 4ik7B-5fubA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6b PUTATIVE SECRETED
LIPASE

(Streptomyces
sp. W007) 		PF01674
(Lipase_2) 		4 LEU A 224
THR A 193
LEU A 221
VAL A 132
 None
 0.75A 4ik7B-5h6bA:
undetectable		 4ik7B-5h6bA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 THR Q 457
ALA Q 459
SER Q 448
THR Q 450
 None
 0.66A 4ik7B-5lcwQ:
undetectable		 4ik7B-5lcwQ:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 THR R 457
ALA R 459
SER R 448
THR R 450
 None
 0.66A 4ik7B-5lcwR:
undetectable		 4ik7B-5lcwR:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B

(Myxococcus
xanthus) 		no annotation 5 LEU D 148
THR D 100
SER D  33
THR D  29
VAL D  27
 None
 1.40A 4ik7B-5n03D:
undetectable		 4ik7B-5n03D:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.86A 4ik7B-5n48A:
undetectable		 4ik7B-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 4 THR A 428
ALA A 430
LEU A 432
THR A 423
 None
 0.77A 4ik7B-5n4aA:
undetectable		 4ik7B-5n4aA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 4 LEU A 395
SER A 518
THR A 520
VAL A 522
 None
 0.59A 4ik7B-5ndxA:
undetectable		 4ik7B-5ndxA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		4 THR A  87
ALA A  89
THR A  98
VAL A 100
 None
 0.79A 4ik7B-5nthA:
undetectable		 4ik7B-5nthA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU W 819
THR W 785
SER W 718
VAL W 714
 None
 0.73A 4ik7B-5o9gW:
undetectable		 4ik7B-5o9gW:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofb MORC FAMILY CW-TYPE
ZINC FINGER PROTEIN
2

(Homo sapiens) 		no annotation 4 LEU B 147
THR B 124
LEU B 128
THR B 119
 None
 0.73A 4ik7B-5ofbB:
undetectable		 4ik7B-5ofbB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc2 DOMAIN OF UNKNOWN
FUNCTION DUF1849

(Brucella
abortus) 		PF08904
(DUF1849) 		4 THR A 219
ALA A 221
THR A 190
VAL A 192
 None
 0.44A 4ik7B-5uc2A:
undetectable		 4ik7B-5uc2A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujv ABSCISIC ACID
RECEPTOR

(Escherichia
coli) 		no annotation 4 ALA A 122
SER A 144
THR A 142
VAL A 140
 None
 0.86A 4ik7B-5ujvA:
undetectable		 4ik7B-5ujvA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v0l ARYL HYDROCARBON
RECEPTOR

(Mus musculus) 		PF00010
(HLH)
PF00989
(PAS) 		4 LYS B 238
ALA B 258
THR B 128
VAL B 126
 None
 0.81A 4ik7B-5v0lB:
undetectable		 4ik7B-5v0lB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6c HEMOLYSIN-RELATED
PROTEIN

(Vibrio cholerae) 		no annotation 4 THR A 890
SER A 886
THR A 929
VAL A 927
 None
 0.83A 4ik7B-5v6cA:
undetectable		 4ik7B-5v6cA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w42 -

(-) 		no annotation 4 ALA H  93
SER H  33
THR H  35
VAL H  37
 None
 0.40A 4ik7B-5w42H:
undetectable		 4ik7B-5w42H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w70 L-GLUTAMINE:2-DEOXY-
SCYLLO-INOSOSE
AMINOTRANSFERASE

(Streptomyces
ribosidificus) 		PF01041
(DegT_DnrJ_EryC1) 		4 THR A 195
ALA A 193
THR A 214
VAL A 212
 None
 0.80A 4ik7B-5w70A:
undetectable		 4ik7B-5w70A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsl KERATINASE

(Meiothermus
taiwanensis) 		no annotation 4 THR A 152
ALA A 154
SER A 130
VAL A 126
 None
 0.58A 4ik7B-5wslA:
undetectable		 4ik7B-5wslA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xll SERINE/THREONINE-PRO
TEIN KINASE PKNI

(Mycobacterium
tuberculosis) 		no annotation 4 THR A 503
LEU A 507
SER A 482
VAL A 487
 None
 0.78A 4ik7B-5xllA:
undetectable		 4ik7B-5xllA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xlm SERINE/THREONINE-PRO
TEIN KINASE PKNI

(Mycobacterium
tuberculosis) 		no annotation 4 THR A 503
LEU A 507
SER A 482
VAL A 487
 None
 0.83A 4ik7B-5xlmA:
undetectable		 4ik7B-5xlmA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xww AMPHB

(Streptomyces
nodosus) 		no annotation 4 THR A 274
ALA A 276
THR A 249
VAL A 247
 None
 0.25A 4ik7B-5xwwA:
undetectable		 4ik7B-5xwwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9a CHORISMATE SYNTHASE

(Pseudomonas
aeruginosa) 		no annotation 4 ALA A  25
LEU A  23
THR A  14
VAL A  12
 None
 0.64A 4ik7B-5z9aA:
undetectable		 4ik7B-5z9aA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bka NITRONATE
MONOOXYGENASE

(Cyberlindnera
mrakii) 		no annotation 4 LEU A  29
THR A  36
ALA A  32
SER A  27
 None
 0.81A 4ik7B-6bkaA:
undetectable		 4ik7B-6bkaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)

(Bacillus cereus) 		no annotation 4 THR A 149
ALA A  69
LEU A  67
VAL A 145
 None
 0.76A 4ik7B-6bvgA:
undetectable		 4ik7B-6bvgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 THR A1773
SER A1784
THR A1786
VAL A1788
 None
 0.62A 4ik7B-6fb3A:
undetectable		 4ik7B-6fb3A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1k TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY C
MEMBER 4A

(Danio rerio) 		no annotation 4 ALA A 210
LEU A 208
SER A 205
VAL A 717
 None
 0.70A 4ik7B-6g1kA:
undetectable		 4ik7B-6g1kA:
22.66