SIMILAR PATTERNS OF AMINO ACIDS FOR 4IK7_A_IMNA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1att ANTITHROMBIN III

(Bos taurus) 		PF00079
(Serpin) 		4 MET A 104
LEU A  93
ALA A  89
THR A  86
 None
 0.84A 4ik7A-1attA:
0.0		 4ik7A-1attA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9h PROTEIN
(3-AMINO-5-HYDROXYBE
NZOIC ACID SYNTHASE)

(Amycolatopsis
mediterranei) 		PF01041
(DegT_DnrJ_EryC1) 		4 THR A 102
ALA A 100
THR A  79
VAL A  81
 None
 0.80A 4ik7A-1b9hA:
0.0		 4ik7A-1b9hA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxt PROTEIN
(STREPTOCOCCAL
SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 LEU A 211
THR A 107
THR A  66
VAL A  64
 None
 0.83A 4ik7A-1bxtA:
0.3		 4ik7A-1bxtA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv CYTOCHROME C1
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
UBIQUINONE-BINDING
PROTEIN QP-C

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF02167
(Cytochrom_C1)
PF02939
(UcrQ)
PF05193
(Peptidase_M16_C) 		4 MET A 445
ALA D 293
THR D 297
VAL G  29
 None
 0.99A 4ik7A-1ezvA:
0.0		 4ik7A-1ezvA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase) 		4 LEU A 392
ALA A 431
THR A 442
VAL A 429
 None
None
None
NAG  A 602 (-4.2A)
 0.94A 4ik7A-1fsuA:
0.0		 4ik7A-1fsuA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fzy UBIQUITIN-CONJUGATIN
G ENZYME E2-24 KDA

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 THR A  73
ALA A 149
THR A 145
VAL A  75
 None
 1.00A 4ik7A-1fzyA:
0.2		 4ik7A-1fzyA:
24.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		7 MET A  13
LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.71A 4ik7A-1gkeA:
21.5		 4ik7A-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmy BILE-SALT-ACTIVATED
LIPASE

(Homo sapiens) 		PF00135
(COesterase) 		5 LYS A 361
LEU A 357
ALA A 360
THR A 352
VAL A 348
 None
 1.44A 4ik7A-1jmyA:
0.0		 4ik7A-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpo MALTOPORIN

(Escherichia
coli) 		PF02264
(LamB) 		4 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 0.97A 4ik7A-1mpoA:
undetectable		 4ik7A-1mpoA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgw BEAN POD MOTTLE
VIRUS LARGE (L)
SUBUNIT

(Bean pod mottle
virus) 		PF02247
(Como_LCP) 		4 THR 2 124
ALA 2 122
THR 2  77
VAL 2  75
 None
 0.79A 4ik7A-1pgw2:
undetectable		 4ik7A-1pgw2:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzn DNA REPAIR AND
RECOMBINATION
PROTEIN RAD51

(Pyrococcus
furiosus) 		PF08423
(Rad51)
PF14520
(HHH_5) 		4 LEU A 234
THR A 282
THR A 134
VAL A 136
 None
 0.72A 4ik7A-1pznA:
undetectable		 4ik7A-1pznA:
18.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.56A 4ik7A-1sn2A:
20.4		 4ik7A-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.66A 4ik7A-1tfpA:
19.6		 4ik7A-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ucs ANTIFREEZE PEPTIDE
RD1

(Lycodichthys
dearborni) 		PF08666
(SAF) 		4 MET A  30
LYS A   2
ALA A   3
VAL A   5
 None
 0.98A 4ik7A-1ucsA:
undetectable		 4ik7A-1ucsA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uik ALPHA PRIME SUBUNIT
OF BETA-CONGLYCININ

(Glycine max) 		PF00190
(Cupin_1) 		4 LEU A 199
THR A 246
THR A 221
VAL A 223
 None
 0.94A 4ik7A-1uikA:
undetectable		 4ik7A-1uikA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5w MEIOTIC
RECOMBINATION
PROTEIN DMC1/LIM15
HOMOLOG

(Homo sapiens) 		PF08423
(Rad51) 		4 LEU A 303
THR A 122
ALA A 124
THR A 267
 None
 0.78A 4ik7A-1v5wA:
undetectable		 4ik7A-1v5wA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlc 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermotoga
maritima) 		PF00180
(Iso_dh) 		4 LEU A 130
THR A 237
THR A 183
VAL A 185
 None
 0.77A 4ik7A-1vlcA:
undetectable		 4ik7A-1vlcA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 THR J 336
ALA J 334
THR J 207
VAL J 205
 None
 0.77A 4ik7A-1wcdJ:
undetectable		 4ik7A-1wcdJ:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybd URIDYLATE KINASE

(Neisseria
meningitidis) 		PF00696
(AA_kinase) 		4 MET A 161
LYS A 163
THR A 237
VAL A 239
 None
GOL  A 250 ( 4.2A)
None
None
 0.78A 4ik7A-1ybdA:
undetectable		 4ik7A-1ybdA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 MET A 403
LYS A 405
LEU A 407
VAL A 364
 None
 0.79A 4ik7A-1zy8A:
undetectable		 4ik7A-1zy8A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4x ANTITHROMBIN-III

(Homo sapiens) 		PF00079
(Serpin) 		4 MET I 103
LEU I  92
ALA I  88
THR I  85
 None
 0.84A 4ik7A-2b4xI:
undetectable		 4ik7A-2b4xI:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2i RV0130

(Mycobacterium
tuberculosis) 		PF01575
(MaoC_dehydratas) 		4 LEU A  91
ALA A 143
THR A 129
VAL A 131
 None
 0.58A 4ik7A-2c2iA:
undetectable		 4ik7A-2c2iA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cv6 SEED STORAGE PROTEIN

(Vigna radiata) 		PF00190
(Cupin_1) 		4 LEU A  66
THR A 113
THR A  88
VAL A  90
 None
 0.94A 4ik7A-2cv6A:
undetectable		 4ik7A-2cv6A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eez ALANINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 MET A   1
LEU A  87
ALA A  66
VAL A  33
 None
 0.98A 4ik7A-2eezA:
undetectable		 4ik7A-2eezA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f17 THIAMIN
PYROPHOSPHOKINASE 1

(Mus musculus) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 172
THR A 231
THR A 197
VAL A 195
 None
 0.92A 4ik7A-2f17A:
undetectable		 4ik7A-2f17A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB

(Neisseria
meningitidis) 		PF08534
(Redoxin) 		4 THR A  93
ALA A  95
THR A 124
VAL A 122
 None
 0.95A 4ik7A-2fy6A:
undetectable		 4ik7A-2fy6A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gyq YCFI, PUTATIVE
STRUCTURAL PROTEIN

(Rhodopseudomonas
palustris) 		PF05974
(DUF892) 		4 MET A  36
LEU A  85
ALA A  89
THR A  92
 None
None
None
ZN  A 410 ( 4.6A)
 0.94A 4ik7A-2gyqA:
undetectable		 4ik7A-2gyqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4u THIOESTERASE
SUPERFAMILY MEMBER 2

(Homo sapiens) 		PF03061
(4HBT) 		4 LYS A 136
THR A 116
ALA A 114
VAL A 106
 None
 0.75A 4ik7A-2h4uA:
undetectable		 4ik7A-2h4uA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hma PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE

(Streptococcus
pneumoniae) 		PF03054
(tRNA_Me_trans) 		4 LEU A 359
ALA A 290
THR A 329
VAL A 331
 None
 0.88A 4ik7A-2hmaA:
undetectable		 4ik7A-2hmaA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq1 PROTEIN PHOSPHATASE
2C KAPPA, PPM1K

(Homo sapiens) 		PF00481
(PP2C) 		4 LEU A 201
THR A 191
ALA A 193
VAL A 125
 None
 0.83A 4ik7A-2iq1A:
undetectable		 4ik7A-2iq1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ksb SUBSTANCE-P RECEPTOR

(Homo sapiens) 		PF00001
(7tm_1) 		4 MET A 299
THR A  45
THR A  40
VAL A  44
 None
 1.00A 4ik7A-2ksbA:
undetectable		 4ik7A-2ksbA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpr MALTOPORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 1.01A 4ik7A-2mprA:
undetectable		 4ik7A-2mprA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3i HYPOTHETICAL PROTEIN

(Chromobacterium
violaceum) 		PF06032
(DUF917) 		4 MET A  64
LEU A 158
ALA A 156
THR A 154
 None
 0.90A 4ik7A-2o3iA:
undetectable		 4ik7A-2o3iA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C

(Escherichia
coli) 		PF05175
(MTS)
PF08468
(MTS_N) 		4 THR A 239
ALA A 235
THR A 171
VAL A 169
 None
 0.83A 4ik7A-2pjdA:
undetectable		 4ik7A-2pjdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzi UNCHARACTERIZED
PROTEIN

(Streptococcus
thermophilus) 		PF08860
(DUF1827) 		4 LYS A   2
ALA A  31
THR A  34
VAL A  36
 None
 0.93A 4ik7A-2qziA:
undetectable		 4ik7A-2qziA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 MET A 102
LEU A  98
ALA A 163
VAL A 236
 None
 0.78A 4ik7A-2rdyA:
undetectable		 4ik7A-2rdyA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rik TITIN

(Oryctolagus
cuniculus) 		PF07679
(I-set) 		4 LYS A  22
THR A  56
THR A  51
VAL A  53
 None
 0.96A 4ik7A-2rikA:
undetectable		 4ik7A-2rikA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vaw CELL DIVISION
PROTEIN FTSZ

(Pseudomonas
aeruginosa) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 LEU A 161
ALA A 224
THR A 314
VAL A 312
 None
 0.92A 4ik7A-2vawA:
undetectable		 4ik7A-2vawA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vq9 RNASE 1

(Danio rerio) 		PF00074
(RnaseA) 		4 LYS A 103
THR A  88
THR A  49
VAL A  47
 None
None
CL  A1128 (-4.2A)
None
 0.81A 4ik7A-2vq9A:
undetectable		 4ik7A-2vq9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y24 XYLANASE

(Dickeya
chrysanthemi) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 LEU A 275
THR A 378
THR A 409
VAL A 384
 None
 0.66A 4ik7A-2y24A:
undetectable		 4ik7A-2y24A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvx MG2+ TRANSPORTER
MGTE

(Thermus
thermophilus) 		PF00571
(CBS)
PF01769
(MgtE)
PF03448
(MgtE_N) 		4 LEU A 408
THR A 434
THR A 429
VAL A 433
 None
 1.00A 4ik7A-2yvxA:
undetectable		 4ik7A-2yvxA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z9v ASPARTATE
AMINOTRANSFERASE

(Mesorhizobium
loti) 		PF00266
(Aminotran_5) 		4 LEU A  14
THR A 344
THR A 307
VAL A 309
 None
 0.90A 4ik7A-2z9vA:
undetectable		 4ik7A-2z9vA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI

(Streptococcus
mutans) 		PF02324
(Glyco_hydro_70) 		4 LYS A 549
LEU A 544
ALA A 548
THR A 640
 None
 1.00A 4ik7A-3aibA:
undetectable		 4ik7A-3aibA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 LYS A 528
LEU A 526
ALA A 482
VAL A 558
 None
 0.67A 4ik7A-3aqpA:
undetectable		 4ik7A-3aqpA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b43 TITIN

(Oryctolagus
cuniculus) 		PF07679
(I-set) 		4 LYS A 214
THR A 248
THR A 243
VAL A 245
 None
 0.78A 4ik7A-3b43A:
undetectable		 4ik7A-3b43A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bij UNCHARACTERIZED
PROTEIN GSU0716

(Geobacter
sulfurreducens) 		PF00656
(Peptidase_C14) 		4 MET A  78
ALA A   8
THR A  49
VAL A  47
 None
 0.92A 4ik7A-3bijA:
undetectable		 4ik7A-3bijA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blw ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 LEU A 125
THR A 235
THR A 179
VAL A 181
 None
 0.76A 4ik7A-3blwA:
undetectable		 4ik7A-3blwA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvm ENTEROTOXIN TYPE C-3

(Staphylococcus
aureus) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 LEU A 214
THR A 109
THR A  66
VAL A  64
 None
 0.80A 4ik7A-3bvmA:
undetectable		 4ik7A-3bvmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxp PUTATIVE
LIPASE/ESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 LEU A 152
ALA A 193
THR A 223
VAL A 221
 None
 0.68A 4ik7A-3bxpA:
undetectable		 4ik7A-3bxpA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4n UNCHARACTERIZED
PROTEIN DR_0571

(Deinococcus
radiodurans) 		PF01266
(DAO) 		4 THR A 168
ALA A 166
THR A  87
VAL A  85
 None
 0.79A 4ik7A-3c4nA:
undetectable		 4ik7A-3c4nA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7l LIN1944 PROTEIN

(Listeria
innocua) 		PF13561
(adh_short_C2) 		4 LEU A   5
THR A 110
THR A 108
VAL A 152
 None
 0.78A 4ik7A-3d7lA:
undetectable		 4ik7A-3d7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddr HASR PROTEIN

(Serratia
marcescens) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 MET A 324
THR A 350
THR A 377
VAL A 379
 None
 0.88A 4ik7A-3ddrA:
undetectable		 4ik7A-3ddrA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f5o THIOESTERASE
SUPERFAMILY MEMBER 2

(Homo sapiens) 		PF03061
(4HBT) 		4 LYS A 136
THR A 116
ALA A 114
VAL A 106
 UOC  A 149 (-3.1A)
None
None
None
 0.80A 4ik7A-3f5oA:
undetectable		 4ik7A-3f5oA:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		5 MET A  13
LYS A  15
LEU A  17
ALA A 108
THR A 118
 None
IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-3.1A)
None
 1.30A 4ik7A-3fc8A:
23.7		 4ik7A-3fc8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		7 MET A  13
LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-4.9A)
IFA  A3000 (-3.1A)
IFA  A3000 ( 4.9A)
None
 0.52A 4ik7A-3fc8A:
23.7		 4ik7A-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4i GLYCOSYLTRANSFERASE
GTFA,
GLYCOSYLTRANSFERASE

(Actinoplanes
teichomyceticus;
Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28)
PF04101
(Glyco_tran_28_C) 		4 LEU A 377
THR A 198
ALA A 373
THR A 370
 None
 0.96A 4ik7A-3h4iA:
undetectable		 4ik7A-3h4iA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgq HDA1 COMPLEX SUBUNIT
3

(Saccharomyces
cerevisiae) 		PF11496
(HDA2-3) 		4 MET A 201
LEU A 238
THR A 133
VAL A 178
 None
 0.86A 4ik7A-3hgqA:
undetectable		 4ik7A-3hgqA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hnr PROBABLE
METHYLTRANSFERASE
BT9727_4108

(Bacillus
thuringiensis) 		PF08241
(Methyltransf_11) 		4 LEU A 200
ALA A 144
THR A 113
VAL A 111
 None
 0.65A 4ik7A-3hnrA:
undetectable		 4ik7A-3hnrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4u MAJOR CAPSID PROTEIN

(Bordetella
virus BPP1) 		no annotation 4 LEU A  11
THR A  92
ALA A  94
THR A 218
 None
 0.75A 4ik7A-3j4uA:
undetectable		 4ik7A-3j4uA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jy6 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Lactobacillus
brevis) 		PF13407
(Peripla_BP_4) 		4 LEU A 189
THR A 243
ALA A 245
VAL A 271
 None
 0.84A 4ik7A-3jy6A:
undetectable		 4ik7A-3jy6A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k20 OXIDOREDUCTASE

(Corynebacterium
diphtheriae) 		PF03358
(FMN_red) 		4 LEU A  93
ALA A   9
THR A  83
VAL A  81
 None
 1.01A 4ik7A-3k20A:
undetectable		 4ik7A-3k20A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX EXONUCLEASE
1
PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2

(Sulfolobus
solfataricus) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		4 LEU B 202
THR A 226
THR A 195
VAL A 193
 None
 0.92A 4ik7A-3l7zB:
undetectable		 4ik7A-3l7zB:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtr NEURAL CELL ADHESION
MOLECULE 1

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 LEU A 444
THR A 435
THR A 480
VAL A 482
 None
 0.83A 4ik7A-3mtrA:
undetectable		 4ik7A-3mtrA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE

(Coccidioides
immitis) 		PF02502
(LacAB_rpiB) 		4 MET A  74
ALA A  12
THR A  40
VAL A  42
 None
 0.91A 4ik7A-3qd5A:
undetectable		 4ik7A-3qd5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmg OCTAPRENYL-DIPHOSPHA
TE SYNTHASE

(Bacteroides
thetaiotaomicron) 		PF00348
(polyprenyl_synt) 		4 LEU A  74
THR A 127
ALA A  70
THR A  67
 None
 0.87A 4ik7A-3rmgA:
undetectable		 4ik7A-3rmgA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4y THIAMIN
PYROPHOSPHOKINASE 1

(Homo sapiens) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 172
THR A 231
THR A 197
VAL A 195
 None
 0.96A 4ik7A-3s4yA:
undetectable		 4ik7A-3s4yA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 LYS A 197
LEU A 193
THR A 200
ALA A 196
 None
 0.96A 4ik7A-3s51A:
undetectable		 4ik7A-3s51A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sic STREPTOMYCES
SUBTILISIN INHIBITOR
(SSI)

(Streptomyces
albogriseolus) 		PF00720
(SSI) 		4 THR I  32
ALA I  30
THR I  15
VAL I  13
 None
 0.75A 4ik7A-3sicI:
undetectable		 4ik7A-3sicI:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tch PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 LYS A 163
THR A 173
THR A  99
VAL A  97
 None
 0.92A 4ik7A-3tchA:
undetectable		 4ik7A-3tchA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thc BETA-GALACTOSIDASE

(Homo sapiens) 		PF01301
(Glyco_hydro_35)
PF13364
(BetaGal_dom4_5) 		4 LEU A 633
THR A 637
ALA A 635
THR A 378
 None
 0.72A 4ik7A-3thcA:
undetectable		 4ik7A-3thcA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1h 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus sp.
(in: Bacteria)) 		PF00180
(Iso_dh) 		4 LEU A 130
THR A 240
THR A 186
VAL A 188
 None
 0.88A 4ik7A-3u1hA:
undetectable		 4ik7A-3u1hA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
BETA

(Methanothermobacter
marburgensis) 		PF04422
(FrhB_FdhB_N)
PF04432
(FrhB_FdhB_C) 		4 LEU C 128
THR C 207
THR C 221
VAL C 219
 None
FAD  C1283 (-4.6A)
None
None
 0.66A 4ik7A-4ci0C:
undetectable		 4ik7A-4ci0C:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dsq PEROXIREDOXIN TYPE-2

(Saccharomyces
cerevisiae) 		PF08534
(Redoxin) 		4 THR A  52
ALA A  54
THR A  90
VAL A  88
 None
 0.69A 4ik7A-4dsqA:
undetectable		 4ik7A-4dsqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8e GLUTATHIONE
S-TRANSFERASE

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 THR A  23
ALA A  19
THR A 163
VAL A 159
 None
 0.94A 4ik7A-4e8eA:
undetectable		 4ik7A-4e8eA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g97 RESPONSE REGULATOR
RECEIVER

(Brucella
abortus) 		PF00072
(Response_reg) 		4 MET A 143
LEU A 194
ALA A 190
VAL A 215
 None
 0.92A 4ik7A-4g97A:
undetectable		 4ik7A-4g97A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gga CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 LEU A 176
THR A 457
ALA A 459
THR A 450
 None
 0.91A 4ik7A-4ggaA:
undetectable		 4ik7A-4ggaA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hnr CHEMOTAXIS PROTEIN
CHEY

(Vibrio cholerae) 		PF00072
(Response_reg) 		4 LEU A  81
ALA A   6
THR A  30
VAL A  28
 None
 0.86A 4ik7A-4hnrA:
undetectable		 4ik7A-4hnrA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hx3 NEUTRAL PROTEINASE
INHIBITOR SCNPI

(Streptomyces
caespitosus) 		PF00720
(SSI) 		4 THR B  28
ALA B  26
THR B  11
VAL B   9
 None
 0.82A 4ik7A-4hx3B:
undetectable		 4ik7A-4hx3B:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jq9 DIHYDROLIPOYL
DEHYDROGENASE

(Escherichia
coli) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 MET A 396
LYS A 398
ALA A 412
VAL A 357
 None
 0.93A 4ik7A-4jq9A:
undetectable		 4ik7A-4jq9A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2x POLYKETIDE
OXYGENASE/HYDROXYLAS
E

(Streptomyces
rimosus) 		PF01494
(FAD_binding_3) 		4 LEU A 113
ALA A 115
THR A  28
VAL A  30
 None
 0.98A 4ik7A-4k2xA:
undetectable		 4ik7A-4k2xA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqx KETOL-ACID
REDUCTOISOMERASE

(Slackia exigua) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 LYS A 191
LEU A  15
ALA A 161
VAL A 163
 None
 0.93A 4ik7A-4kqxA:
undetectable		 4ik7A-4kqxA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 LEU A  86
ALA A  41
THR A  11
VAL A   9
 None
 0.75A 4ik7A-4l1yA:
undetectable		 4ik7A-4l1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ld1 UNCHARACTERIZED
PROTEIN

(Danio rerio) 		PF07202
(Tcp10_C) 		4 LYS A1022
THR A1032
THR A1040
VAL A1038
 PGE  A1202 ( 3.6A)
None
None
None
 0.96A 4ik7A-4ld1A:
undetectable		 4ik7A-4ld1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mr0 PLASMIN AND
FIBRONECTIN-BINDING
PROTEIN A

(Streptococcus
pneumoniae) 		PF12708
(Pectate_lyase_3)
PF13229
(Beta_helix) 		4 LYS A 426
LEU A 424
ALA A 470
THR A 503
 None
CA  A 702 ( 4.5A)
None
None
 0.71A 4ik7A-4mr0A:
undetectable		 4ik7A-4mr0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ote LIPOPROTEIN

(Clostridioides
difficile) 		PF03180
(Lipoprotein_9) 		4 LYS A 176
LEU A 178
THR A 129
ALA A 131
 None
 0.94A 4ik7A-4oteA:
undetectable		 4ik7A-4oteA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6t GLYCOSYL HYDROLASE,
FAMILY 18

(Pseudomonas
protegens) 		PF00704
(Glyco_hydro_18) 		4 MET A  78
LEU A  96
THR A  64
THR A  99
 None
 0.99A 4ik7A-4q6tA:
undetectable		 4ik7A-4q6tA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjk PHOSPHOPANTETHEINYL
TRANSFERASE PPTT

(Mycobacterium
tuberculosis) 		PF01648
(ACPS) 		5 LYS A 156
LEU A 152
THR A 159
ALA A 155
THR A 223
 None
None
COA  A 301 ( 3.8A)
None
None
 1.48A 4ik7A-4qjkA:
undetectable		 4ik7A-4qjkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF01648
(ACPS)
PF13416
(SBP_bac_8) 		5 LYS A 527
LEU A 523
THR A 530
ALA A 526
THR A 594
 None
None
COA  A 602 ( 4.4A)
None
None
 1.45A 4ik7A-4qvhA:
undetectable		 4ik7A-4qvhA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
cyanogenus;
Streptomyces
fradiae) 		PF06722
(DUF1205) 		5 LYS A 225
LEU A 221
THR A 227
ALA A 224
THR A 248
 None
 1.43A 4ik7A-4rihA:
undetectable		 4ik7A-4rihA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u89 PHOSPHOPANTETHEINYL
TRANSFERASE PPTT

(Mycobacterium
tuberculosis) 		PF01648
(ACPS) 		5 LYS A 156
LEU A 152
THR A 159
ALA A 155
THR A 223
 None
None
COA  A 301 ( 4.5A)
None
None
 1.46A 4ik7A-4u89A:
undetectable		 4ik7A-4u89A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uie SURFACE LAYER
PROTEIN

(Geobacillus
stearothermophilus) 		no annotation 4 LEU A 891
THR A 903
THR A 949
VAL A 951
 None
 0.87A 4ik7A-4uieA:
undetectable		 4ik7A-4uieA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wl2 PUTATIVE EXPORTED
CHOLOYLGLYCINE
HYDROLASE

(Pectobacterium
atrosepticum) 		PF02275
(CBAH) 		4 LEU A  86
THR A  17
THR A 279
VAL A 281
 None
 0.90A 4ik7A-4wl2A:
undetectable		 4ik7A-4wl2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b5x LIMITING
CO2-INDUCIBLE
PROTEIN LCIC

(Chlamydomonas
reinhardtii) 		no annotation 4 MET A 115
ALA A 176
THR A 292
VAL A 290
 None
 0.82A 4ik7A-5b5xA:
undetectable		 4ik7A-5b5xA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5equ SNON,SNON

(Streptomyces
nogalater) 		PF05721
(PhyH) 		4 LEU A 108
THR A 227
ALA A 229
VAL A 149
 None
 0.69A 4ik7A-5equA:
undetectable		 4ik7A-5equA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fai RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE
NEP1

(Homo sapiens) 		PF03587
(EMG1) 		4 LYS A 232
LEU A 228
THR A 235
ALA A 231
 None
 0.88A 4ik7A-5faiA:
undetectable		 4ik7A-5faiA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1c DNA REPAIR PROTEIN
RAD51 HOMOLOG 1

(Homo sapiens) 		PF08423
(Rad51)
PF14520
(HHH_5) 		4 LEU A 302
THR A 123
THR A 266
VAL A 264
 None
 0.73A 4ik7A-5h1cA:
undetectable		 4ik7A-5h1cA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmm EXODEOXYRIBONUCLEASE

(Escherichia
virus T5) 		PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N) 		4 MET A  23
LEU A  30
THR A  63
THR A 121
 None
 0.82A 4ik7A-5hmmA:
undetectable		 4ik7A-5hmmA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5joz NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43B

(Bacteroides
ovatus) 		PF04616
(Glyco_hydro_43) 		4 LEU A 424
THR A 439
THR A 447
VAL A 444
 None
 1.00A 4ik7A-5jozA:
undetectable		 4ik7A-5jozA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans) 		no annotation 4 LEU B 841
THR B 848
ALA B 844
THR B 759
 None
 0.91A 4ik7A-5khnB:
undetectable		 4ik7A-5khnB:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l8v DNA REPAIR AND
RECOMBINATION
PROTEIN RADA

(Pyrococcus
furiosus) 		PF08423
(Rad51) 		4 LEU A 234
THR A 282
THR A 134
VAL A 136
 None
 0.84A 4ik7A-5l8vA:
undetectable		 4ik7A-5l8vA:
21.85