SIMILAR PATTERNS OF AMINO ACIDS FOR 4IK6_B_LURB201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1914 SIGNAL RECOGNITION
PARTICLE 9/14 FUSION
PROTEIN

(Mus musculus) 		PF02290
(SRP14)
PF05486
(SRP9-21) 		4 GLU A2012
ALA A2060
LEU A2058
VAL A2026
 None
 0.88A 4ik6B-1914A:
1.0		 4ik6B-1914A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cx1 ENDOGLUCANASE C

(Cellulomonas
fimi) 		PF02018
(CBM_4_9) 		4 GLU A  64
THR A 150
ALA A 152
VAL A   7
 None
 0.77A 4ik6B-1cx1A:
0.0		 4ik6B-1cx1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eq9 CHYMOTRYPSIN

(Solenopsis
invicta) 		PF00089
(Trypsin) 		4 LEU A 155
GLU A 157
THR A 137
VAL A 200
 None
 0.88A 4ik6B-1eq9A:
undetectable		 4ik6B-1eq9A:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		6 MET A  13
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
 None
 0.73A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		6 MET A  13
LEU A  17
GLU A  54
THR A 106
ALA A 108
VAL A 121
 None
 0.69A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		6 MET A  13
LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
 None
 0.83A 4ik6B-1gkeA:
20.3		 4ik6B-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i0a DELTA CRYSTALLIN I

(Meleagris
gallopavo) 		PF00206
(Lyase_1)
PF14698
(ASL_C2) 		4 LEU A 174
THR A 181
ALA A 177
LEU A 173
 None
 0.96A 4ik6B-1i0aA:
undetectable		 4ik6B-1i0aA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE

(Caenorhabditis
elegans) 		PF00293
(NUDIX) 		4 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.90A 4ik6B-1kt9A:
0.0		 4ik6B-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ktw IOTA-CARRAGEENASE

(Alteromonas sp.
ATCC 43554) 		PF12708
(Pectate_lyase_3) 		4 MET A 244
LEU A 234
THR A 223
VAL A 189
 None
 0.81A 4ik6B-1ktwA:
undetectable		 4ik6B-1ktwA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpo MALTOPORIN

(Escherichia
coli) 		PF02264
(LamB) 		4 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 0.96A 4ik6B-1mpoA:
0.0		 4ik6B-1mpoA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pn4 PEROXISOMAL
HYDRATASE-DEHYDROGEN
ASE-EPIMERASE

(Candida
tropicalis) 		PF01575
(MaoC_dehydratas) 		4 MET A 222
LEU A  21
ALA A 213
LEU A 211
 None
 0.95A 4ik6B-1pn4A:
undetectable		 4ik6B-1pn4A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pq5 TRYPSIN

(Fusarium
oxysporum) 		PF00089
(Trypsin) 		4 LYS A 154
THR A 134
ALA A 136
VAL A 200
 None
 0.77A 4ik6B-1pq5A:
undetectable		 4ik6B-1pq5A:
18.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.53A 4ik6B-1sn2A:
21.0		 4ik6B-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		4 LYS A  15
LEU A  17
GLU A  54
LEU A 110
 None
 0.91A 4ik6B-1sn2A:
21.0		 4ik6B-1sn2A:
54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		4 LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.74A 4ik6B-1tfpA:
18.9		 4ik6B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		5 LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.54A 4ik6B-1tfpA:
18.9		 4ik6B-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vfg POLY A POLYMERASE

(Aquifex
aeolicus) 		PF01743
(PolyA_pol) 		4 GLU A 172
ALA A 156
LEU A 154
VAL A 140
 None
 0.98A 4ik6B-1vfgA:
undetectable		 4ik6B-1vfgA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER

(Saccharomyces
cerevisiae) 		PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1) 		4 MET C 284
LEU C 269
LEU C 272
VAL C 280
 None
 0.87A 4ik6B-1wa5C:
undetectable		 4ik6B-1wa5C:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2af5 ENGINEERED OUTER
SURFACE PROTEIN A
(OSPA) WITH THE
INSERTED TWO
BETA-HAIRPINS

(Borreliella
burgdorferi) 		PF00820
(Lipoprotein_1) 		4 LYS A 279
LEU A 281
LEU A 269
VAL A 273
 None
 0.86A 4ik6B-2af5A:
undetectable		 4ik6B-2af5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2

(Carnivore
protoparvovirus
1) 		PF00740
(Parvo_coat) 		4 LYS A  52
LEU A  54
THR A  62
VAL A 534
 None
 0.84A 4ik6B-2casA:
1.5		 4ik6B-2casA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hls PROTEIN DISULFIDE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF13192
(Thioredoxin_3) 		4 GLU A 178
THR A  89
ALA A  91
LEU A  93
 None
 0.95A 4ik6B-2hlsA:
undetectable		 4ik6B-2hlsA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq1 PROTEIN PHOSPHATASE
2C KAPPA, PPM1K

(Homo sapiens) 		PF00481
(PP2C) 		4 LEU A 201
THR A 191
ALA A 193
LEU A 195
 None
 0.64A 4ik6B-2iq1A:
undetectable		 4ik6B-2iq1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx8 TRNA-SPECIFIC
ADENOSINE DEAMINASE

(Streptococcus
pyogenes) 		PF14437
(MafB19-deam) 		4 LEU A 144
GLU A 141
THR A  87
VAL A  43
 None
 0.91A 4ik6B-2nx8A:
undetectable		 4ik6B-2nx8A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obx 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
1

(Mesorhizobium
loti) 		PF00885
(DMRL_synthase) 		4 LEU A 111
ALA A  73
LEU A  75
VAL A  12
 None
 0.82A 4ik6B-2obxA:
undetectable		 4ik6B-2obxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogv MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR
PRECURSOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 649
THR A 654
ALA A 652
VAL A 659
 None
 0.97A 4ik6B-2ogvA:
undetectable		 4ik6B-2ogvA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7m 5-FORMAMINOIMIDAZOLE
-4-CARBOXAMIDE-1-(BE
TA)-D-RIBOFURANOSYL
5'-MONOPHOSPHATE
SYNTHETASE

(Methanocaldococcus
jannaschii) 		PF06849
(DUF1246)
PF06973
(DUF1297) 		4 LEU A 137
GLU A 273
ALA A 135
LEU A 132
 None
 0.97A 4ik6B-2r7mA:
undetectable		 4ik6B-2r7mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 MET A 102
LEU A  98
ALA A 163
LEU A 165
 None
 0.77A 4ik6B-2rdyA:
undetectable		 4ik6B-2rdyA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 MET A 102
LEU A  98
ALA A 163
VAL A 236
 None
 0.73A 4ik6B-2rdyA:
undetectable		 4ik6B-2rdyA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reo PUTATIVE
SULFOTRANSFERASE 1C3

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		4 LEU A 113
THR A  53
LEU A  49
VAL A 137
 None
A3P  A 401 ( 4.8A)
None
None
 0.93A 4ik6B-2reoA:
undetectable		 4ik6B-2reoA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9t SLIT HOMOLOG 2
PROTEIN N-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU B 363
THR B 415
ALA B 391
LEU B 367
 None
 0.95A 4ik6B-2v9tB:
undetectable		 4ik6B-2v9tB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmh FUCOLECTIN-RELATED
PROTEIN

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		4 LEU A 466
THR A 539
LEU A 543
VAL A 579
 None
 0.77A 4ik6B-2wmhA:
undetectable		 4ik6B-2wmhA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 MET A 737
LEU A 733
ALA A 710
LEU A 712
 None
 0.97A 4ik6B-2ww2A:
undetectable		 4ik6B-2ww2A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x05 EXO-BETA-D-GLUCOSAMI
NIDASE

(Amycolatopsis
orientalis) 		PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 722
THR A 704
ALA A 702
LEU A 700
 None
 0.79A 4ik6B-2x05A:
undetectable		 4ik6B-2x05A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans) 		PF07971
(Glyco_hydro_92) 		4 MET A 751
LEU A 747
ALA A 724
LEU A 726
 None
 0.73A 4ik6B-2xsgA:
undetectable		 4ik6B-2xsgA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqp PROBABLE SECDF
PROTEIN-EXPORT
MEMBRANE PROTEIN

(Thermus
thermophilus) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 LYS A 528
LEU A 526
ALA A 482
VAL A 558
 None
 0.77A 4ik6B-3aqpA:
undetectable		 4ik6B-3aqpA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aup BASIC 7S GLOBULIN

(Glycine max) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 MET A 263
GLU A 229
THR A 360
VAL A 272
 None
 0.97A 4ik6B-3aupA:
undetectable		 4ik6B-3aupA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bx8 ENGINEERED HUMAN
LIPOCALIN 2

(Homo sapiens) 		PF00061
(Lipocalin) 		4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.95A 4ik6B-3bx8A:
undetectable		 4ik6B-3bx8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e1k GALACTOSE/LACTOSE
METABOLISM
REGULATORY PROTEIN
GAL80

(Kluyveromyces
lactis) 		PF01408
(GFO_IDH_MocA) 		4 GLU A 122
ALA A 124
LEU A 433
VAL A 205
 None
 0.96A 4ik6B-3e1kA:
undetectable		 4ik6B-3e1kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 GLU A 647
THR A 297
ALA A 299
LEU A 301
 None
 0.82A 4ik6B-3eb7A:
undetectable		 4ik6B-3eb7A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eyt UNCHARACTERIZED
PROTEIN SPOA0173

(Ruegeria
pomeroyi) 		PF00578
(AhpC-TSA) 		4 LEU A 139
THR A 146
ALA A 142
LEU A 138
 None
 0.95A 4ik6B-3eytA:
undetectable		 4ik6B-3eytA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		8 MET A  13
LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
None
IFA  A3000 (-4.9A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
None
 0.52A 4ik6B-3fc8A:
22.6		 4ik6B-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 LEU P 102
THR P 106
ALA P   7
LEU P   5
 None
FAD  P 449 (-4.1A)
FAD  P 449 ( 4.7A)
None
 0.92A 4ik6B-3fg2P:
undetectable		 4ik6B-3fg2P:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwe 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE III

(Burkholderia
pseudomallei) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 LEU A  86
THR A 150
ALA A 148
LEU A 146
 None
 0.79A 4ik6B-3gweA:
undetectable		 4ik6B-3gweA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgq HDA1 COMPLEX SUBUNIT
3

(Saccharomyces
cerevisiae) 		PF11496
(HDA2-3) 		4 MET A 201
LEU A 238
THR A 133
VAL A 178
 None
 0.91A 4ik6B-3hgqA:
undetectable		 4ik6B-3hgqA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic1 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Haemophilus
influenzae) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LYS A  54
THR A 125
ALA A 127
LEU A 129
 None
 0.85A 4ik6B-3ic1A:
undetectable		 4ik6B-3ic1A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic1 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Haemophilus
influenzae) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LYS A  54
THR A 125
ALA A 127
VAL A  61
 None
 0.74A 4ik6B-3ic1A:
undetectable		 4ik6B-3ic1A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwf PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Listeria
innocua) 		PF02082
(Rrf2) 		4 LEU A  11
THR A 118
ALA A  76
VAL A 114
 None
 0.90A 4ik6B-3lwfA:
undetectable		 4ik6B-3lwfA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntd FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Shewanella
loihica) 		PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LYS A   3
LEU A   5
GLU A  28
LEU A 109
 None
 0.78A 4ik6B-3ntdA:
undetectable		 4ik6B-3ntdA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc4 OXIDOREDUCTASE,
PYRIDINE
NUCLEOTIDE-DISULFIDE
FAMILY

(Enterococcus
faecalis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 181
ALA A 153
LEU A 180
VAL A 150
 None
 0.96A 4ik6B-3oc4A:
undetectable		 4ik6B-3oc4A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oky PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI) 		4 LYS A 138
LEU A 140
GLU A 150
ALA A 128
 None
 0.76A 4ik6B-3okyA:
undetectable		 4ik6B-3okyA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd2 EUKARYOTIC
TRANSLATION
INITIATION FACTOR
2-ALPHA KINASE 3

(Mus musculus) 		PF00069
(Pkinase) 		4 MET B 886
LEU B 882
ALA B 653
LEU B 655
 None
 0.82A 4ik6B-3qd2B:
undetectable		 4ik6B-3qd2B:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvd RUBRERYTHRIN

(Pyrococcus
furiosus) 		PF02915
(Rubrerythrin) 		4 THR A  81
ALA A 118
LEU A 120
VAL A  84
 None
 0.92A 4ik6B-3qvdA:
undetectable		 4ik6B-3qvdA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ts7 GERANYLTRANSTRANSFER
ASE

(Methylococcus
capsulatus) 		PF00348
(polyprenyl_synt) 		4 LEU A  55
THR A  62
ALA A  58
LEU A  54
 None
 0.96A 4ik6B-3ts7A:
undetectable		 4ik6B-3ts7A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE

(Klebsiella
pneumoniae) 		PF14486
(DUF4432) 		4 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.83A 4ik6B-3ty1A:
undetectable		 4ik6B-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u3g RIBONUCLEASE H

(uncultured
organism) 		no annotation 4 MET D  76
LEU D 114
THR D   8
VAL D  23
 None
 0.91A 4ik6B-3u3gD:
undetectable		 4ik6B-3u3gD:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9p NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Mus musculus) 		PF00061
(Lipocalin) 		4 LEU C 140
THR C 132
LEU C 144
VAL C 117
 None
 0.95A 4ik6B-3u9pC:
undetectable		 4ik6B-3u9pC:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ain GLYCINE BETAINE
TRANSPORTER BETP

(Corynebacterium
glutamicum) 		PF02028
(BCCT) 		4 LEU A 403
THR A 410
ALA A 406
LEU A 402
 None
 0.96A 4ik6B-4ainA:
undetectable		 4ik6B-4ainA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c5f MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE C

(Escherichia
coli) 		PF01464
(SLT)
PF11873
(DUF3393) 		4 LEU A 277
THR A 240
LEU A 274
VAL A 237
 None
 0.89A 4ik6B-4c5fA:
undetectable		 4ik6B-4c5fA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dlo BRAIN-SPECIFIC
ANGIOGENESIS
INHIBITOR 3

(Homo sapiens) 		PF01825
(GPS)
PF02793
(HRM)
PF16489
(GAIN) 		4 LYS A 850
LEU A 852
GLU A 806
THR A 844
 None
 0.65A 4ik6B-4dloA:
undetectable		 4ik6B-4dloA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmo N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Bacillus cereus) 		PF00797
(Acetyltransf_2) 		4 LEU A 233
THR A 221
ALA A 226
LEU A 228
 None
 0.93A 4ik6B-4dmoA:
undetectable		 4ik6B-4dmoA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es1 BH0342 PROTEIN

(Bacillus
halodurans) 		PF09827
(CRISPR_Cas2) 		4 LEU A  71
THR A   6
LEU A   2
VAL A  38
 None
 0.73A 4ik6B-4es1A:
undetectable		 4ik6B-4es1A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2n D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE,
NAD-BINDING

(Polaromonas sp.
JS666) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 THR A  76
ALA A  78
LEU A  80
VAL A  53
 None
 0.54A 4ik6B-4g2nA:
undetectable		 4ik6B-4g2nA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g34 EUKARYOTIC
TRANSLATION
INITIATION FACTOR
2-ALPHA KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 MET A 887
LEU A 883
ALA A 656
LEU A 658
 924  A1101 (-3.7A)
None
None
None
 0.82A 4ik6B-4g34A:
undetectable		 4ik6B-4g34A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h2k SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Haemophilus
influenzae) 		PF01546
(Peptidase_M20) 		4 LYS A  54
THR A 125
ALA A 127
LEU A 129
 None
 0.64A 4ik6B-4h2kA:
undetectable		 4ik6B-4h2kA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hn0 PUTATIVE 3-EPIMERASE
IN D-ALLOSE PATHWAY

(Streptomyces
bikiniensis) 		PF00908
(dTDP_sugar_isom) 		4 LEU A  56
ALA A 118
LEU A 120
VAL A  84
 None
 0.75A 4ik6B-4hn0A:
undetectable		 4ik6B-4hn0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7z APOCYTOCHROME F

(Mastigocladus
laminosus) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 LEU C 151
ALA C  74
LEU C  76
VAL C  72
 None
HEM  C 301 (-4.8A)
None
HEM  C 301 (-4.9A)
 0.95A 4ik6B-4i7zC:
undetectable		 4ik6B-4i7zC:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jot ENOYL-COA HYDRATASE,
PUTATIVE

(Deinococcus
radiodurans) 		PF00378
(ECH_1) 		4 LEU A   8
THR A  23
ALA A  25
LEU A  27
 None
 0.75A 4ik6B-4jotA:
undetectable		 4ik6B-4jotA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kdz TRNA
(CYTIDINE(34)-2'-O)-
METHYLTRANSFERASE

(Escherichia
coli) 		PF00588
(SpoU_methylase) 		4 LYS A 119
THR A  79
ALA A  77
LEU A  75
 None
 0.85A 4ik6B-4kdzA:
undetectable		 4ik6B-4kdzA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myc IRON-SULFUR CLUSTERS
TRANSPORTER ATM1,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 LEU A 645
GLU A 653
THR A 465
VAL A 627
 None
 0.84A 4ik6B-4mycA:
undetectable		 4ik6B-4mycA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ote LIPOPROTEIN

(Clostridioides
difficile) 		PF03180
(Lipoprotein_9) 		4 LYS A 176
LEU A 178
THR A 129
ALA A 131
 None
 0.60A 4ik6B-4oteA:
undetectable		 4ik6B-4oteA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qae NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		PF00061
(Lipocalin) 		4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.94A 4ik6B-4qaeA:
undetectable		 4ik6B-4qaeA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ruw ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE

(Beutenbergia
cavernae) 		PF03372
(Exo_endo_phos) 		4 LEU A 325
THR A  57
LEU A  53
VAL A  90
 None
 0.98A 4ik6B-4ruwA:
undetectable		 4ik6B-4ruwA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhb IRON-CHELATOR
UTILIZATION PROTEIN

(Thermobifida
fusca) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		4 LEU A 207
THR A 214
ALA A 210
LEU A 206
 None
 0.98A 4ik6B-4yhbA:
undetectable		 4ik6B-4yhbA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1p CELL WALL SURFACE
ANCHOR PROTEIN

(Streptococcus
agalactiae) 		PF16364
(Antigen_C) 		4 LYS A 202
LEU A 180
GLU A 204
VAL A 238
 None
 0.86A 4ik6B-4z1pA:
undetectable		 4ik6B-4z1pA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0m INTRON-ENCODED
ENDONUCLEASE I-SCEI

(Saccharomyces
cerevisiae) 		PF03161
(LAGLIDADG_2) 		4 MET A 358
LEU A 374
THR A 403
LEU A 373
 None
 0.94A 4ik6B-5a0mA:
undetectable		 4ik6B-5a0mA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb6 PROBABLE
ADENYLYL-SULFATE
KINASE

(Synechocystis
sp. PCC 6803) 		PF01583
(APS_kinase) 		4 LEU A  72
THR A  98
LEU A  73
VAL A  95
 None
 0.74A 4ik6B-5cb6A:
undetectable		 4ik6B-5cb6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d28 GM-CSF/IL-2
INHIBITION FACTOR

(Orf virus) 		no annotation 4 MET A  44
LEU A  40
ALA A 212
LEU A 214
 None
 0.94A 4ik6B-5d28A:
undetectable		 4ik6B-5d28A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7z LACTOYLGLUTATHIONE
LYASE

(Zea mays) 		PF00903
(Glyoxalase) 		4 LYS A 183
LEU A 180
THR A 192
LEU A 196
 None
 0.90A 4ik6B-5d7zA:
undetectable		 4ik6B-5d7zA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5equ SNON,SNON

(Streptomyces
nogalater) 		PF05721
(PhyH) 		4 LEU A 108
THR A 227
ALA A 229
VAL A 149
 None
 0.63A 4ik6B-5equA:
undetectable		 4ik6B-5equA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 THR A 995
ALA A 997
LEU A 999
VAL A1050
 None
 0.96A 4ik6B-5fkuA:
undetectable		 4ik6B-5fkuA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 NICASTRIN

(Homo sapiens) 		PF05450
(Nicastrin) 		4 LEU A 498
THR A 304
ALA A 308
LEU A 312
 None
 0.90A 4ik6B-5fn4A:
undetectable		 4ik6B-5fn4A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6b PUTATIVE SECRETED
LIPASE

(Streptomyces
sp. W007) 		PF01674
(Lipase_2) 		4 LEU A 224
THR A 193
LEU A 221
VAL A 132
 None
 0.72A 4ik6B-5h6bA:
undetectable		 4ik6B-5h6bA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT

(Oplophorus
gracilirostris) 		no annotation 4 LEU A 150
GLU A 140
THR A 159
LEU A 163
 None
 0.93A 4ik6B-5iboA:
undetectable		 4ik6B-5iboA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis) 		PF05853
(BKACE) 		4 LEU A 751
THR A 836
ALA A 834
LEU A 832
 None
 0.93A 4ik6B-5ikzA:
undetectable		 4ik6B-5ikzA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbr UNCHARACTERIZED
PROTEIN BCAV_2135

(Beutenbergia
cavernae) 		PF12802
(MarR_2) 		4 LEU A  48
THR A  39
LEU A  50
VAL A  81
 None
 0.88A 4ik6B-5jbrA:
undetectable		 4ik6B-5jbrA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo9 RIBITOL
2-DEHYDROGENASE

(Bradyrhizobium
japonicum) 		PF00106
(adh_short) 		4 LEU A  82
THR A  13
ALA A  11
VAL A  37
 None
 0.88A 4ik6B-5jo9A:
undetectable		 4ik6B-5jo9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khp NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		PF00061
(Lipocalin) 		4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.95A 4ik6B-5khpA:
undetectable		 4ik6B-5khpA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kku POLYKETIDE SYNTHASE
TYPE I

(Bacillus
amyloliquefaciens) 		PF14765
(PS-DH) 		4 GLU A  90
THR A  81
LEU A  45
VAL A   8
 None
 0.89A 4ik6B-5kkuA:
undetectable		 4ik6B-5kkuA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ko3 ORF1A

(Middle East
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		4 LYS A 291
ALA A 282
LEU A 284
VAL A 268
 ACT  A 406 (-2.9A)
None
None
None
 0.96A 4ik6B-5ko3A:
undetectable		 4ik6B-5ko3A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l5g PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		4 LYS A 138
LEU A 140
GLU A 150
ALA A 128
 None
 0.82A 4ik6B-5l5gA:
undetectable		 4ik6B-5l5gA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.89A 4ik6B-5n48A:
undetectable		 4ik6B-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkn NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
LOC  A 201 (-3.5A)
None
None
 0.96A 4ik6B-5nknA:
undetectable		 4ik6B-5nknA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)

(Burkholderia
vietnamiensis) 		PF00982
(Glyco_transf_20) 		4 THR A  63
ALA A  65
LEU A  67
VAL A  38
 None
 0.70A 4ik6B-5tvgA:
undetectable		 4ik6B-5tvgA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txr 5-AMINOLEVULINATE
SYNTHASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		no annotation 4 LEU B 248
THR B 332
LEU B 277
VAL B 346
 None
 0.88A 4ik6B-5txrB:
undetectable		 4ik6B-5txrB:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u89 AMINO ACID
ADENYLATION DOMAIN
PROTEIN

(Geobacillus sp.
Y4.1MC1) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF13193
(AMP-binding_C) 		4 MET A1180
LEU A1176
ALA A1164
LEU A1166
 None
 0.89A 4ik6B-5u89A:
undetectable		 4ik6B-5u89A:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uag DNA-DIRECTED RNA
POLYMERASE SUBUNIT
ALPHA

(Escherichia
coli) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		4 LYS A 200
GLU A 188
THR A  27
VAL A  14
 None
 0.73A 4ik6B-5uagA:
undetectable		 4ik6B-5uagA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8u ORF1AB PROTEIN

(Middle East
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		4 LYS A 291
ALA A 282
LEU A 284
VAL A 268
 None
 0.96A 4ik6B-5w8uA:
undetectable		 4ik6B-5w8uA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykn PROBABLE
LYSINE-SPECIFIC
DEMETHYLASE JMJ14

(Arabidopsis
thaliana) 		no annotation 4 LEU A 444
THR A 451
ALA A 447
LEU A 443
 None
 0.96A 4ik6B-5yknA:
undetectable		 4ik6B-5yknA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byi BETA-MANNOSIDASE

(Xanthomonas
citri) 		no annotation 4 LEU A 242
ALA A 258
LEU A 260
VAL A 304
 None
 0.65A 4ik6B-6byiA:
3.9		 4ik6B-6byiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gqz -

(-) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.98A 4ik6B-6gqzA:
undetectable		 4ik6B-6gqzA:
undetectable