SIMILAR PATTERNS OF AMINO ACIDS FOR 4IJI_H_BEZH501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aql BILE-SALT ACTIVATED
LIPASE

(Bos taurus) 		PF00135
(COesterase) 		4 ASN A 142
ALA A 113
SER A 114
TYR A 125
 None
 1.11A 4ijiH-1aqlA:
undetectable		 4ijiH-1aqlA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ciy CRYIA(A)

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 ASN A 533
ALA A 552
TYR A 528
ARG A 566
 None
 1.10A 4ijiH-1ciyA:
4.3		 4ijiH-1ciyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dju AROMATIC
AMINOTRANSFERASE

(Pyrococcus
horikoshii) 		PF00155
(Aminotran_1_2) 		4 ALA A 352
SER A 351
VAL A 361
ARG A 362
 None
 1.16A 4ijiH-1djuA:
undetectable		 4ijiH-1djuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		4 ASN A 408
ALA A 407
VAL A 417
TYR A 342
 None
 1.00A 4ijiH-1e4oA:
0.0		 4ijiH-1e4oA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE
UBIQUINOL OXIDASE

(Escherichia
coli;
Escherichia
coli) 		PF00115
(COX1)
PF00116
(COX2)
PF06481
(COX_ARM) 		4 ASN B 172
ALA B 208
SER B 207
ARG A 482
 None
None
None
HEM  A1001 (-2.9A)
 0.97A 4ijiH-1fftB:
undetectable		 4ijiH-1fftB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		4 ASN A 550
VAL A 624
TYR A 622
ARG A 627
 None
 1.16A 4ijiH-1k32A:
undetectable		 4ijiH-1k32A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogy PERIPLASMIC NITRATE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASN A 358
ALA A 156
SER A 155
ARG A 392
 None
 1.14A 4ijiH-1ogyA:
0.8		 4ijiH-1ogyA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF02570
(CbiC) 		4 ASN A 129
SER A 130
VAL A  96
ARG A  94
 None
 1.13A 4ijiH-1ou0A:
undetectable		 4ijiH-1ou0A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpo QUINOLINATE ACID
PHOSPHORIBOSYL
TRANSFERASE

(Mycobacterium
tuberculosis) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 ALA A 118
SER A 115
VAL A  84
ARG A  83
 None
 1.13A 4ijiH-1qpoA:
undetectable		 4ijiH-1qpoA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 37 KDA
SUBUNIT
ACTIVATOR 1 40 KDA
SUBUNIT

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08542
(Rep_fac_C)
PF00004
(AAA)
PF08542
(Rep_fac_C) 		4 ALA B 310
SER B 311
VAL C 297
ARG C 296
 None
 1.03A 4ijiH-1sxjB:
undetectable		 4ijiH-1sxjB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5t ORC2

(Aeropyrum
pernix) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		4 ALA A 340
SER A 341
ARG A 315
TYR A 345
 None
 1.16A 4ijiH-1w5tA:
undetectable		 4ijiH-1w5tA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy7 HYPOTHETICAL PROTEIN
PH1948

(Pyrococcus
horikoshii) 		PF05175
(MTS) 		4 ASN A  33
ALA A  34
SER A  36
VAL A  62
 None
None
None
SAH  A1001 (-3.4A)
 1.12A 4ijiH-1wy7A:
undetectable		 4ijiH-1wy7A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yni SUCCINYLARGININE
DIHYDROLASE

(Escherichia
coli) 		PF04996
(AstB) 		4 ASN A  25
ALA A  27
SER A  28
TYR A  18
 SUG  A1001 (-3.9A)
None
SUG  A1001 (-2.7A)
None
 0.98A 4ijiH-1yniA:
undetectable		 4ijiH-1yniA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 ALA A 633
SER A 630
VAL A 682
ARG A 685
 None
 0.99A 4ijiH-1z68A:
undetectable		 4ijiH-1z68A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azq CATECHOL
1,2-DIOXYGENASE

(Pseudomonas
putida) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		4 ASN A 173
VAL A 120
ARG A 189
ARG A 121
 None
 1.14A 4ijiH-2azqA:
undetectable		 4ijiH-2azqA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ca4 SULFITE:CYTOCHROME C
OXIDOREDUCTASE
SUBUNIT A

(Starkeya
novella) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 ASN A  91
VAL A 134
TYR A 186
ARG A 132
 None
 1.14A 4ijiH-2ca4A:
undetectable		 4ijiH-2ca4A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 ALA A 546
SER A 543
VAL A 477
ARG A 479
 None
 1.12A 4ijiH-2cvtA:
undetectable		 4ijiH-2cvtA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwy ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1

(Homo sapiens) 		PF02883
(Alpha_adaptinC2) 		4 ALA A 563
SER A 562
VAL A 627
ARG A 607
 None
 1.01A 4ijiH-2dwyA:
undetectable		 4ijiH-2dwyA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f46 HYPOTHETICAL PROTEIN

(Neisseria
meningitidis) 		PF04273
(DUF442) 		4 ALA A 124
VAL A  90
ARG A  94
ARG A 121
 None
 1.06A 4ijiH-2f46A:
undetectable		 4ijiH-2f46A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG

(Homo sapiens) 		PF04078
(Rcd1) 		4 ASN A  72
ALA A  68
SER A  71
ARG A 114
 None
 1.05A 4ijiH-2fv2A:
undetectable		 4ijiH-2fv2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2him L-ASPARAGINASE 1

(Escherichia
coli) 		PF00710
(Asparaginase) 		4 ASN A 250
ALA A 252
VAL A 226
ARG A 227
 None
 0.92A 4ijiH-2himA:
undetectable		 4ijiH-2himA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhe TRANSCRIPTION
REGULATOR TYRR

(Escherichia
coli) 		PF13188
(PAS_8) 		4 ASN A 106
ALA A 108
SER A 109
VAL A 174
 None
 1.06A 4ijiH-2jheA:
undetectable		 4ijiH-2jheA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASN A 311
ALA A 144
SER A 143
ARG A 354
 None
 1.02A 4ijiH-2jirA:
undetectable		 4ijiH-2jirA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASN A 320
ALA A 144
SER A 143
ARG A 354
 None
 1.11A 4ijiH-2jirA:
undetectable		 4ijiH-2jirA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kue SERINE/THREONINE-PRO
TEIN KINASE PKNB

(Mycobacterium
tuberculosis) 		PF03793
(PASTA) 		4 ALA A 479
SER A 478
VAL A 484
ARG A 451
 None
 1.11A 4ijiH-2kueA:
undetectable		 4ijiH-2kueA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mgy TRANSLOCATOR PROTEIN

(Mus musculus) 		PF03073
(TspO_MBR) 		4 ALA A  50
VAL A  26
ARG A  27
ARG A  46
 PKA  A 201 ( 4.8A)
PKA  A 201 (-3.6A)
None
None
 1.16A 4ijiH-2mgyA:
undetectable		 4ijiH-2mgyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n1b GTP-BINDING NUCLEAR
PROTEIN RAN

(Homo sapiens) 		PF00071
(Ras) 		4 ASN A 122
ALA A 151
SER A 150
VAL A 187
 None
 1.15A 4ijiH-2n1bA:
undetectable		 4ijiH-2n1bA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nuj THIOESTERASE
SUPERFAMILY

(Jannaschia) 		PF13279
(4HBT_2) 		4 ASN A  44
ALA A  47
VAL A  32
ARG A  33
 None
 1.09A 4ijiH-2nujA:
undetectable		 4ijiH-2nujA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nya PERIPLASMIC NITRATE
REDUCTASE

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ASN A 348
ALA A 147
SER A 146
ARG A 382
 None
 1.16A 4ijiH-2nyaA:
undetectable		 4ijiH-2nyaA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohc TRNA-SPLICING
ENDONUCLEASE

(Thermoplasma
acidophilum) 		PF01974
(tRNA_int_endo) 		4 ALA A  74
VAL A  67
ARG A  71
TYR A  41
 None
 1.16A 4ijiH-2ohcA:
undetectable		 4ijiH-2ohcA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vcy TRANS-2-ENOYL-COA
REDUCTASE

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ASN A 190
ALA A 191
SER A 192
VAL A 200
 None
SO4  A1378 (-3.6A)
None
None
 1.09A 4ijiH-2vcyA:
undetectable		 4ijiH-2vcyA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vul GH11 XYLANASE

(Escherichia
coli) 		PF00457
(Glyco_hydro_11) 		4 SER A 114
VAL A  92
TYR A 119
ARG A 145
 None
 1.10A 4ijiH-2vulA:
undetectable		 4ijiH-2vulA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1j PUTATIVE SORTASE

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 ASN A 156
VAL A 188
TYR A 163
ARG A 209
 None
 1.07A 4ijiH-2w1jA:
undetectable		 4ijiH-2w1jA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xgy RELIK CAPSID
N-TERMINAL DOMAIN

(Oryctolagus
cuniculus) 		PF00607
(Gag_p24) 		4 ASN A  57
VAL A 128
TYR A 124
ARG A 103
 GOL  A1138 (-4.0A)
None
None
GOL  A1138 (-4.0A)
 0.91A 4ijiH-2xgyA:
undetectable		 4ijiH-2xgyA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqy HYPOTHETICAL PROTEIN
TTHA0303

(Thermus
thermophilus) 		PF12867
(DinB_2) 		4 ASN A 131
ALA A 133
VAL A  64
ARG A  67
 None
 1.08A 4ijiH-2yqyA:
undetectable		 4ijiH-2yqyA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr3 MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE

(Homo sapiens) 		PF07679
(I-set) 		4 ASN A  85
ALA A  11
VAL A  35
ARG A  36
 None
 1.14A 4ijiH-2yr3A:
undetectable		 4ijiH-2yr3A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2

(Homo sapiens) 		PF06920
(DHR-2) 		4 SER A1436
VAL A1439
TYR A1342
ARG A1364
 None
 1.12A 4ijiH-3b13A:
3.9		 4ijiH-3b13A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bsf AT4G34840

(Arabidopsis
thaliana) 		PF01048
(PNP_UDP_1) 		4 ASN A 181
ALA A 124
SER A 163
ARG A 128
 None
 1.00A 4ijiH-3bsfA:
undetectable		 4ijiH-3bsfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2v 3'-5'-EXONUCLEASE

(Saccharomyces
cerevisiae) 		PF01026
(TatD_DNase) 		4 ALA A 338
SER A 339
VAL A 396
TYR A 342
 None
 1.13A 4ijiH-3e2vA:
undetectable		 4ijiH-3e2vA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gir AMINOMETHYLTRANSFERA
SE

(Bartonella
henselae) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 ASN A 244
ALA A 302
SER A 319
ARG A 301
 None
 1.13A 4ijiH-3girA:
undetectable		 4ijiH-3girA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ic9 DIHYDROLIPOAMIDE
DEHYDROGENASE

(Colwellia
psychrerythraea) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ALA A  60
SER A  61
VAL A  84
ARG A  87
 None
 0.77A 4ijiH-3ic9A:
undetectable		 4ijiH-3ic9A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr3 NAD-DEPENDENT
DEACETYLASE

(Thermotoga
maritima) 		PF02146
(SIR2) 		4 ASN A  99
ALA A  22
SER A  25
VAL A 232
 None
 1.10A 4ijiH-3jr3A:
undetectable		 4ijiH-3jr3A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3js8 CHOLESTEROL OXIDASE

(Chromobacterium
sp. DS-1) 		PF01565
(FAD_binding_4)
PF09129
(Chol_subst-bind) 		4 ALA A 150
SER A 250
VAL A 269
ARG A 253
 None
 1.09A 4ijiH-3js8A:
undetectable		 4ijiH-3js8A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvo HYDROXYSTEROID
DEHYDROGENASE-LIKE
PROTEIN 2

(Homo sapiens) 		PF00106
(adh_short) 		4 ALA A 104
SER A 103
VAL A  75
ARG A  76
 NAP  A 502 ( 3.7A)
NAP  A 501 (-3.4A)
NAP  A 501 (-3.6A)
NAP  A 502 (-3.0A)
 1.12A 4ijiH-3kvoA:
undetectable		 4ijiH-3kvoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfu DNA HELICASE II

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 ASN A 282
SER A 285
VAL A 603
ARG A 605
 None
None
None
SO4  A1000 (-2.8A)
 1.13A 4ijiH-3lfuA:
undetectable		 4ijiH-3lfuA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lv4 GLYCOSIDE HYDROLASE
YXIA

(Bacillus
licheniformis) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		4 ASN A  69
VAL A 349
ARG A 348
ARG A 366
 None
 1.06A 4ijiH-3lv4A:
undetectable		 4ijiH-3lv4A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvu ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Ruegeria
pomeroyi) 		PF00496
(SBP_bac_5) 		4 ASN A 521
ALA A 525
VAL A 563
ARG A 333
 None
 1.14A 4ijiH-3lvuA:
undetectable		 4ijiH-3lvuA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT

(Alcaligenes
faecalis) 		PF01804
(Penicil_amidase) 		4 ALA A  54
VAL A  49
ARG A  45
ARG A  46
 None
 1.14A 4ijiH-3ml0A:
undetectable		 4ijiH-3ml0A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r95 MCCE PROTEIN

(Escherichia
coli) 		PF13302
(Acetyltransf_3) 		4 ALA A 150
SER A 148
VAL A 117
ARG A 154
 None
ACO  A 601 (-3.2A)
ACO  A 601 (-3.8A)
ACO  A 601 (-3.5A)
 1.00A 4ijiH-3r95A:
undetectable		 4ijiH-3r95A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Schizosaccharomyces
pombe;
Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe) 		PF11976
(Rad60-SLD)
no annotation 		4 ALA B 660
SER B 659
VAL A  39
ARG A  38
 None
 1.14A 4ijiH-3tixB:
undetectable		 4ijiH-3tixB:
18.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tot GLUTATHIONE
S-TRANSFERASE
PROTEIN

(Ralstonia
solanacearum) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 ALA A  10
SER A  11
VAL A 107
ARG A 110
 ACT  A 227 (-3.5A)
ACT  A 231 (-2.5A)
ACT  A 231 ( 4.7A)
ACT  A 227 (-4.7A)
 1.07A 4ijiH-3totA:
27.0		 4ijiH-3totA:
42.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tot GLUTATHIONE
S-TRANSFERASE
PROTEIN

(Ralstonia
solanacearum) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		6 ALA A  10
SER A  11
VAL A 107
ARG A 110
TYR A 168
ARG A 172
 ACT  A 227 (-3.5A)
ACT  A 231 (-2.5A)
ACT  A 231 ( 4.7A)
ACT  A 227 (-4.7A)
ACT  A 227 (-4.5A)
ACT  A 227 (-3.9A)
 0.79A 4ijiH-3totA:
27.0		 4ijiH-3totA:
42.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL

(Homo sapiens) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 ASN A 171
ALA A 190
VAL A 202
ARG A 192
 None
 1.15A 4ijiH-3u1kA:
undetectable		 4ijiH-3u1kA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7u RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 ASN A 338
ALA A 308
VAL A 370
ARG A 371
 None
 1.10A 4ijiH-3u7uA:
undetectable		 4ijiH-3u7uA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vb9 UNCHARACTERIZED
PROTEIN VPA0735

(Vibrio
parahaemolyticus) 		PF06742
(DUF1214)
PF06863
(DUF1254) 		4 ALA A 298
SER A 300
ARG A 405
TYR A 303
 None
 1.11A 4ijiH-3vb9A:
undetectable		 4ijiH-3vb9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vtx MAMA

(Candidatus
Magnetobacterium
bavaricum) 		PF00515
(TPR_1)
PF13174
(TPR_6)
PF13181
(TPR_8)
PF13414
(TPR_11) 		4 ASN A 122
VAL A 105
TYR A 115
ARG A 137
 None
 1.05A 4ijiH-3vtxA:
undetectable		 4ijiH-3vtxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		4 ALA A 747
VAL A 729
TYR A 715
ARG A 749
 None
 1.06A 4ijiH-3wfzA:
undetectable		 4ijiH-3wfzA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 ASN A 120
ALA A 122
VAL A 127
ARG A 125
 None
 1.12A 4ijiH-4dxyA:
undetectable		 4ijiH-4dxyA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 ASN A 277
ALA A 130
VAL A 153
TYR A 118
 None
 1.08A 4ijiH-4ecnA:
undetectable		 4ijiH-4ecnA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emi TODA

(Pseudomonas
putida) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		4 ALA A  49
SER A  45
VAL A 133
ARG A 137
 None
 1.08A 4ijiH-4emiA:
undetectable		 4ijiH-4emiA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gga CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 ASN A 196
ALA A 211
SER A 210
ARG A 174
 None
 1.14A 4ijiH-4ggaA:
undetectable		 4ijiH-4ggaA:
21.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4glt GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN

(Methylobacillus
flagellatus) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 SER A   9
VAL A 105
TYR A 165
ARG A 169
 GSH  A 301 (-2.7A)
GSH  A 301 ( 4.8A)
GSH  A 301 (-4.7A)
GSH  A 301 (-4.1A)
 0.67A 4ijiH-4gltA:
25.9		 4ijiH-4gltA:
35.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 ASN A  76
ALA A 122
VAL A 311
ARG A 307
 None
MLI  A1000 (-3.9A)
None
MLI  A1000 (-3.0A)
 1.11A 4ijiH-4gysA:
undetectable		 4ijiH-4gysA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1l ANI2.3 TCR B CHAIN

(Escherichia
coli) 		PF07686
(V-set) 		4 ALA H  85
VAL H  76
TYR H  87
ARG H  34
 None
 1.00A 4ijiH-4h1lH:
undetectable		 4ijiH-4h1lH:
23.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF

(Pseudomonas
fluorescens) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		7 ASN A   6
ALA A   8
SER A   9
VAL A 109
ARG A 112
TYR A 167
ARG A 171
 None
ACT  A 303 ( 3.9A)
ACT  A 302 ( 4.2A)
None
None
ACT  A 303 (-4.5A)
ACT  A 303 (-4.0A)
 0.30A 4ijiH-4id0A:
32.5		 4ijiH-4id0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iuy SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE

(Acinetobacter
baumannii) 		PF00106
(adh_short) 		4 ASN A  92
ALA A 125
VAL A  73
ARG A  70
 None
 1.14A 4ijiH-4iuyA:
undetectable		 4ijiH-4iuyA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc2 ASFP504

(Alcyonium) 		PF01353
(GFP) 		4 ASN A 195
ALA A  59
VAL A 157
ARG A  91
 CRQ  A  64 ( 3.3A)
CRQ  A  64 ( 3.9A)
None
CRQ  A  64 ( 3.0A)
 1.14A 4ijiH-4jc2A:
undetectable		 4ijiH-4jc2A:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4jed GLUTATHIONE
S-TRANSFERASE

(Methylobacterium
radiotolerans) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 SER A  14
VAL A 110
ARG A 174
TYR A 170
 GTS  A 302 (-2.5A)
None
None
None
 0.93A 4ijiH-4jedA:
23.2		 4ijiH-4jedA:
33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwp GCN5-RELATED
N-ACETYLTRANSFERASE

(Brucella
abortus) 		PF13420
(Acetyltransf_4) 		4 ASN A 126
ALA A 128
SER A 129
VAL A  87
 ACO  A 201 (-3.4A)
ACO  A 201 (-3.4A)
ACO  A 201 (-3.2A)
ACO  A 201 (-4.2A)
 1.06A 4ijiH-4jwpA:
undetectable		 4ijiH-4jwpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m00 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		4 ASN A 374
ALA A 376
SER A 375
VAL A 403
 None
 1.14A 4ijiH-4m00A:
undetectable		 4ijiH-4m00A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m01 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		no annotation 4 ASN A 374
ALA A 376
SER A 375
VAL A 403
 None
 1.07A 4ijiH-4m01A:
undetectable		 4ijiH-4m01A:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mk3 GLUTATHIONE
S-TRANSFERASE

(Cupriavidus
metallidurans) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 SER A   9
ARG A 108
TYR A 166
ARG A 170
 GSF  A 304 (-2.4A)
None
None
None
 0.58A 4ijiH-4mk3A:
27.0		 4ijiH-4mk3A:
35.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Geobacter
sulfurreducens) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		4 SER A 925
VAL A  58
TYR A  75
ARG A  54
 None
 1.03A 4ijiH-4nmeA:
undetectable		 4ijiH-4nmeA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmh PECTINESTERASE

(Sitophilus
oryzae) 		PF01095
(Pectinesterase) 		4 ASN A 106
ALA A 170
SER A 169
VAL A 151
 None
 1.09A 4ijiH-4pmhA:
undetectable		 4ijiH-4pmhA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2b EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Ochrobactrum
anthropi) 		PF01547
(SBP_bac_1) 		4 ASN A 384
ALA A 383
VAL A 204
TYR A 212
 None
 1.16A 4ijiH-4r2bA:
undetectable		 4ijiH-4r2bA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1r ATP-DEPENDENT
6-PHOSPHOFRUCTOKINAS
E, PLATELET TYPE

(Homo sapiens) 		PF00365
(PFK) 		4 ALA A 570
SER A 569
ARG A 665
ARG A 576
 None
None
PO4  A 803 (-3.7A)
PO4  A 803 (-3.8A)
 0.94A 4ijiH-4u1rA:
undetectable		 4ijiH-4u1rA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udr GLUCOSE-METHANOL-CHO
LINE OXIDOREDUCTASE

(Methylovorus
sp. MP688) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ASN A 395
ALA A  77
VAL A 462
ARG A 459
 None
 0.88A 4ijiH-4udrA:
undetectable		 4ijiH-4udrA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ASN A 532
ALA A 250
VAL A 289
ARG A 303
 None
 1.04A 4ijiH-4ynuA:
undetectable		 4ijiH-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ASN A 532
ALA A 250
VAL A 304
ARG A 303
 None
 1.09A 4ijiH-4ynuA:
undetectable		 4ijiH-4ynuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywn NADH-FMN
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF01613
(Flavin_Reduct) 		4 ASN A 140
ALA A 122
SER A 121
VAL A  53
 None
 1.02A 4ijiH-4ywnA:
undetectable		 4ijiH-4ywnA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z42 UREASE SUBUNIT ALPHA

(Yersinia
enterocolitica) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 ASN C 384
ALA C 564
TYR C 569
ARG C 568
 None
 1.09A 4ijiH-4z42C:
undetectable		 4ijiH-4z42C:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zn0 THIOREDOXIN
REDUCTASE

(Methanosarcina
mazei) 		PF07992
(Pyr_redox_2) 		4 ASN A 153
ALA A 181
VAL A 188
ARG A 187
 None
 1.16A 4ijiH-4zn0A:
undetectable		 4ijiH-4zn0A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia pestis) 		PF00149
(Metallophos) 		4 ASN A 342
ALA A  64
SER A  65
ARG A  71
 None
 1.11A 4ijiH-5eqvA:
undetectable		 4ijiH-5eqvA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fno MANGANESE
LIPOXYGENASE

(Magnaporthe
oryzae) 		PF00305
(Lipoxygenase) 		4 ASN A 275
ALA A 225
SER A 224
ARG A 214
 None
 1.17A 4ijiH-5fnoA:
undetectable		 4ijiH-5fnoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gha SULFUR TRANSFERASE
TTUA

(Thermus
thermophilus) 		PF01171
(ATP_bind_3) 		4 VAL A  66
ARG A  69
TYR A 209
ARG A 213
 None
 1.14A 4ijiH-5ghaA:
undetectable		 4ijiH-5ghaA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5m ALPHA-CATENIN-LIKE
PROTEIN HMP-1

(Caenorhabditis
elegans) 		PF01044
(Vinculin) 		4 ALA A 507
SER A 509
VAL A 381
ARG A 378
 None
 1.16A 4ijiH-5h5mA:
2.4		 4ijiH-5h5mA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho9 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		4 ASN A  82
VAL A 426
ARG A 425
ARG A 443
 None
None
SO4  A 711 ( 4.7A)
SO4  A 711 (-3.1A)
 1.12A 4ijiH-5ho9A:
undetectable		 4ijiH-5ho9A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hp6 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF13385
(Laminin_G_3)
PF16369
(GH43_C) 		4 ASN A  82
VAL A 426
ARG A 425
ARG A 443
 None
 1.05A 4ijiH-5hp6A:
undetectable		 4ijiH-5hp6A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF01821
(ANATO)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 ASN B1348
ALA B 982
SER B 983
ARG B1291
 None
 1.15A 4ijiH-5jpnB:
6.0		 4ijiH-5jpnB:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lrb ALPHA-1,4 GLUCAN
PHOSPHORYLASE

(Hordeum vulgare) 		PF00343
(Phosphorylase) 		4 ASN A 572
ALA A 571
VAL A 581
TYR A 418
 None
 1.14A 4ijiH-5lrbA:
undetectable		 4ijiH-5lrbA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6g BETA-GLUCOSIDASE

(Saccharopolyspora
erythraea) 		no annotation 4 ALA A 354
VAL A 361
ARG A 329
ARG A 360
 None
 1.13A 4ijiH-5m6gA:
undetectable		 4ijiH-5m6gA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o25 TMPDE

(Thermotoga
maritima) 		no annotation 4 ASN A 162
ALA A 163
SER A 161
ARG A 159
 None
 0.96A 4ijiH-5o25A:
undetectable		 4ijiH-5o25A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opt 40S RIBOSOMAL
PROTEIN S33,
PUTATIVE

(Trypanosoma
cruzi) 		no annotation 4 ASN U  88
ALA U 108
VAL U  70
ARG U  69
 None
 0.96A 4ijiH-5optU:
undetectable		 4ijiH-5optU:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 4 ASN A 523
ALA A 524
VAL A 529
ARG A 528
 None
 1.03A 4ijiH-5ot4A:
undetectable		 4ijiH-5ot4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tvd TM16

(Trichuris muris) 		PF01161
(PBP) 		4 ASN A  43
ALA A  39
VAL A  50
TYR A  33
 None
 1.08A 4ijiH-5tvdA:
undetectable		 4ijiH-5tvdA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtf VP1

(Hepatovirus A) 		PF12944
(HAV_VP) 		4 ASN A 265
ALA A 268
SER A 266
ARG A 128
 None
 1.07A 4ijiH-5wtfA:
undetectable		 4ijiH-5wtfA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0c NEROL DEHYDROGENASE

(Persicaria
minor) 		no annotation 4 ALA A 324
SER A 161
VAL A 351
ARG A 349
 None
None
None
BME  A 405 (-3.0A)
 1.13A 4ijiH-5z0cA:
undetectable		 4ijiH-5z0cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7k ENDO-ALPHA-(1->5)-L-
ARABINANASE

(Bacillus
licheniformis) 		no annotation 4 ASN A 127
ALA A 128
VAL A  63
ARG A 119
 None
 1.10A 4ijiH-6b7kA:
undetectable		 4ijiH-6b7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwf -

(-) 		no annotation 4 ASN A 622
ALA A 585
VAL A 628
ARG A 629
 None
 0.88A 4ijiH-6bwfA:
undetectable		 4ijiH-6bwfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exn PRE-MRNA-PROCESSING
PROTEIN 45

(Saccharomyces
cerevisiae) 		no annotation 4 ASN K  87
ALA K  89
SER K  90
TYR K  93
 None
C  5 111 ( 3.3A)
None
U  5 110 ( 4.6A)
 1.15A 4ijiH-6exnK:
undetectable		 4ijiH-6exnK:
undetectable