SIMILAR PATTERNS OF AMINO ACIDS FOR 4IIL_A_RBFA401_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpy SERINE
CARBOXYPEPTIDASE

(Saccharomyces
cerevisiae) 		PF00450
(Peptidase_S10) 		5 TYR A 333
TRP A  49
ALA A 148
GLN A 184
GLY A 335
 None
 1.37A 4iilA-1cpyA:
2.2		 4iilA-1cpyA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlm CATECHOL
1,2-DIOXYGENASE

(Acinetobacter
sp. ADP1) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		5 ALA A 158
GLN A 240
ILE A 105
GLY A 219
ASP A 252
 None
 1.33A 4iilA-1dlmA:
undetectable		 4iilA-1dlmA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ftp MUSCLE FATTY ACID
BINDING PROTEIN

(Schistocerca
gregaria) 		PF00061
(Lipocalin) 		5 SER A  55
GLN A  14
ALA A 126
GLN A  98
TYR A  20
 None
 1.44A 4iilA-1ftpA:
undetectable		 4iilA-1ftpA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		5 SER A  21
GLN A 706
ALA A 648
ASP A 602
ILE A 640
 None
 1.48A 4iilA-1j1wA:
5.3		 4iilA-1j1wA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		5 SER A 285
TYR A 342
ASP A  96
TYR A 119
GLY A 284
 None
DAN  A 700 (-3.5A)
DAN  A 700 (-3.3A)
DAN  A 700 (-4.2A)
None
 1.11A 4iilA-1ms8A:
undetectable		 4iilA-1ms8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pem RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
ALPHA CHAIN

(Salmonella
enterica) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF08343
(RNR_N) 		5 SER A 526
TYR A 528
ALA A 505
ASP A 658
GLN A 659
 None
 1.44A 4iilA-1pemA:
undetectable		 4iilA-1pemA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvj PYROGENIC EXOTOXIN B

(Streptococcus
pyogenes) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		5 SER A 280
TYR A 276
ALA A 233
ILE A 261
GLY A 191
 ZFB  A 450 (-4.7A)
None
None
None
ZFB  A 450 ( 4.1A)
 1.24A 4iilA-1pvjA:
undetectable		 4iilA-1pvjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s24 RUBREDOXIN 2

(Pseudomonas
oleovorans) 		PF00301
(Rubredoxin) 		5 ALA A  45
TYR A  50
ILE A   6
TRP A  38
GLY A  19
 None
 1.41A 4iilA-1s24A:
undetectable		 4iilA-1s24A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atm HYALURONOGLUCOSAMINI
DASE

(Vespula
vulgaris) 		PF01630
(Glyco_hydro_56) 		5 TYR A 182
TRP A 210
ALA A 157
GLY A 178
ASP A 107
 None
None
None
None
MES  A 500 (-3.6A)
 1.39A 4iilA-2atmA:
undetectable		 4iilA-2atmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fep CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF13377
(Peripla_BP_3) 		5 TYR A 222
ASP A 276
GLN A 293
ILE A 298
GLY A 126
 SO4  A4397 (-4.2A)
SO4  A4396 (-3.5A)
SO4  A4397 ( 4.9A)
None
None
 1.43A 4iilA-2fepA:
18.8		 4iilA-2fepA:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g28 PYRUVATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00456
(Transketolase_N) 		5 TYR A 598
TYR A 686
ILE A 652
TRP A 578
GLY A 575
 None
 1.48A 4iilA-2g28A:
2.8		 4iilA-2g28A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jtc STREPTOPAIN

(Streptococcus
pyogenes) 		PF01640
(Peptidase_C10) 		5 SER A 135
TYR A 131
ALA A  88
ILE A 116
GLY A  46
 None
 1.21A 4iilA-2jtcA:
undetectable		 4iilA-2jtcA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbr URIDINE
DIPHOSPHO-N-ACETYLEN
OLPYRUVYLGLUCOSAMINE
REDUCTASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		5 TYR A 190
GLN A 288
ALA A 264
GLN A 256
GLY A 123
 EPU  A 402 (-4.1A)
EPU  A 402 (-3.1A)
EPU  A 402 (-3.4A)
None
FAD  A 401 (-4.1A)
 1.12A 4iilA-2mbrA:
undetectable		 4iilA-2mbrA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		5 SER B 403
ALA B 322
GLN B 269
ILE B 372
GLY B 404
 None
 1.06A 4iilA-2rhqB:
undetectable		 4iilA-2rhqB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		5 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  B 503 (-4.4A)
SRM  B 503 (-3.4A)
None
None
 1.15A 4iilA-2v4jA:
undetectable		 4iilA-2v4jA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum) 		PF00026
(Asp) 		5 SER A  79
ALA A  37
ASP A  33
ILE A 297
GLY A  78
 PP6  A 327 (-3.4A)
None
PP6  A 327 ( 2.7A)
PP6  A 327 (-4.2A)
None
 1.44A 4iilA-2wedA:
undetectable		 4iilA-2wedA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsj SULFITE REDUCTASE
ALPHA SUBUNIT

(Desulfomicrobium
norvegicum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		5 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  B 503 (-4.6A)
SRM  B 503 (-3.6A)
None
None
 1.17A 4iilA-2xsjA:
undetectable		 4iilA-2xsjA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ecq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		5 SER A 911
TYR A 913
ALA A 851
GLY A 910
ASP A 181
 None
 1.43A 4iilA-3ecqA:
undetectable		 4iilA-3ecqA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE

(Phanerochaete
chrysosporium) 		PF12708
(Pectate_lyase_3) 		5 SER A  79
TYR A 104
GLN A 176
ASP A 133
GLN A 141
 None
None
GOL  A 764 (-3.1A)
None
None
 1.33A 4iilA-3eqnA:
undetectable		 4iilA-3eqnA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lst CALO1
METHYLTRANSFERASE

(Micromonospora
echinospora) 		PF00891
(Methyltransf_2) 		5 ALA A 245
ASP A 187
ILE A 253
GLY A 236
ASP A 212
 None
SAH  A 346 ( 4.5A)
SAH  A 346 (-4.9A)
None
SAH  A 346 (-3.0A)
 1.49A 4iilA-3lstA:
2.9		 4iilA-3lstA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mm5 SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Archaeoglobus
fulgidus) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		5 SER A 167
TYR A 210
ALA A 315
ASP A 231
GLY A 166
 None
SRM  A 580 (-4.5A)
SRM  A 580 (-3.3A)
None
None
 1.20A 4iilA-3mm5A:
undetectable		 4iilA-3mm5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqn CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		5 TYR A 222
ASP A 276
GLN A 293
ILE A 298
GLY A 126
 None
 1.40A 4iilA-3oqnA:
18.5		 4iilA-3oqnA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF01077
(NIR_SIR) 		5 SER A 169
TYR A 212
ALA A 333
ASP A 233
GLY A 168
 None
SRM  A 582 (-4.6A)
SRM  A 582 (-3.4A)
None
None
 1.19A 4iilA-3or2A:
undetectable		 4iilA-3or2A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
pneumoniae) 		PF12850
(Metallophos_2) 		5 GLN A 114
ALA A 160
ILE A 165
GLY A  65
ASP A  11
 None
None
AMP  A 263 (-4.6A)
None
FE  A 264 (-3.0A)
 1.07A 4iilA-3qfoA:
undetectable		 4iilA-3qfoA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdw GENTAMICIN
RESISTANCE PROTEIN

(Enterococcus
gallinarum) 		PF01636
(APH) 		5 SER A 198
TYR A 233
GLN A 270
ASP A 221
ASP A 218
 None
None
None
MG  A 503 ( 4.7A)
MG  A 502 (-1.9A)
 1.43A 4iilA-3tdwA:
undetectable		 4iilA-3tdwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqx 2-AMINO-3-KETOBUTYRA
TE COENZYME A LIGASE

(Coxiella
burnetii) 		PF00155
(Aminotran_1_2) 		5 SER A 253
TYR A 251
ALA A 212
ASP A 208
GLY A 254
 None
None
None
PLP  A 397 (-2.9A)
None
 1.42A 4iilA-3tqxA:
7.7		 4iilA-3tqxA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ud2 ANKYRIN-1

(Homo sapiens) 		no annotation 5 ALA C1107
GLN C1111
ILE C1131
GLY C1179
ASP C1181
 None
 1.27A 4iilA-3ud2C:
undetectable		 4iilA-3ud2C:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		5 TYR A 527
ALA A 512
TYR A 427
ILE A 477
GLY A 400
 None
 1.31A 4iilA-3welA:
undetectable		 4iilA-3welA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apb FUMARATE HYDRATASE
CLASS II

(Mycobacterium
tuberculosis) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		5 ALA A 384
ASP A 168
GLN A 164
ILE A 211
GLY A 202
 None
 1.37A 4iilA-4apbA:
undetectable		 4iilA-4apbA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3k BETA-GLUCOSIDASE

(Streptococcus
pyogenes) 		PF00232
(Glyco_hydro_1) 		5 TYR A  98
ALA A 105
TYR A  73
ILE A 419
GLY A  16
 None
 1.50A 4iilA-4b3kA:
undetectable		 4iilA-4b3kA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h2h MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Salipiger
bermudensis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 TYR A 134
ALA A 322
ILE A  22
GLY A 263
ASP A 193
 None
None
None
None
MG  A 401 ( 2.7A)
 1.49A 4iilA-4h2hA:
4.1		 4iilA-4h2hA:
25.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hvt POST-PROLINE
CLEAVING ENZYME

(Rickettsia
typhi) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		5 SER A 212
TYR A 214
ASP A 154
TRP A 607
GLY A 604
 None
 1.00A 4iilA-4hvtA:
3.4		 4iilA-4hvtA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l87 SERINE--TRNA LIGASE,
CYTOPLASMIC

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N) 		5 SER A 241
ALA A 373
GLN A  23
TYR A 401
ILE A 135
 None
 1.45A 4iilA-4l87A:
undetectable		 4iilA-4l87A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		5 SER A 355
ASP A 290
GLN A 292
ILE A 294
GLY A 314
 None
 1.19A 4iilA-4p72A:
undetectable		 4iilA-4p72A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry8 PERIPLASMIC BINDING
PROTEIN

(Pseudothermotoga
lettingae) 		PF13407
(Peripla_BP_4) 		5 SER A  47
ALA A  56
GLN A 135
GLY A  46
ASP A 250
 None
None
SR1  A 401 (-3.5A)
None
SR1  A 401 (-2.7A)
 1.41A 4iilA-4ry8A:
19.4		 4iilA-4ry8A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twr NAD BINDING
SITE:NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E:UDP-GLUCOSE
4-EPIMERASE

(Brucella
abortus) 		PF01370
(Epimerase) 		5 SER A  17
ALA A  79
ILE A  54
GLY A  16
ASP A  34
 None
None
NAD  A 400 (-3.8A)
None
NAD  A 400 (-2.7A)
 1.42A 4iilA-4twrA:
6.3		 4iilA-4twrA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7d ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Nakamurella
multipartita) 		PF00561
(Abhydrolase_1) 		5 SER A 206
TRP A 279
ALA A 128
ASP A 249
GLY A  41
 None
 1.15A 4iilA-4y7dA:
2.9		 4iilA-4y7dA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgz ANTIZYME INHIBITOR 1

(Homo sapiens) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		5 SER A 200
ALA A 280
GLN A  54
TYR A 276
GLY A 237
 None
 1.24A 4iilA-4zgzA:
2.2		 4iilA-4zgzA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d8w ENDOGLUCANASE

(Ganoderma
lucidum) 		PF00150
(Cellulase) 		5 TRP A 258
ALA A 272
ASP A 233
ILE A 158
GLY A 308
 None
 1.42A 4iilA-5d8wA:
undetectable		 4iilA-5d8wA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		5 SER A1005
GLN A 921
ILE A 601
GLY A1007
ASP A 608
 G1P  A1201 (-2.5A)
None
None
None
None
 0.96A 4iilA-5h42A:
undetectable		 4iilA-5h42A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5knm LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY B
MEMBER 1

(Homo sapiens) 		PF13895
(Ig_2) 		5 ALA D 176
ASP D 123
GLN D 121
ILE D 158
GLY D 153
 None
 1.34A 4iilA-5knmD:
undetectable		 4iilA-5knmD:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Rhodobacter
sphaeroides) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 TYR A 150
ALA A 116
TYR A 275
ILE A 315
GLY A 323
 None
 1.43A 4iilA-5nv3A:
3.1		 4iilA-5nv3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4x UDP-GLUCOSE
6-DEHYDROGENASE

(Homo sapiens) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		5 SER A 349
TYR A 352
ASP A 379
GLN A 375
GLY A 273
 None
None
None
None
PG5  A 501 (-4.2A)
 1.33A 4iilA-5w4xA:
undetectable		 4iilA-5w4xA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5

(Rice dwarf
virus) 		no annotation 5 SER C 115
ALA C 174
TYR C 178
ILE C 574
GLY C 114
 None
 1.31A 4iilA-5x6xC:
5.0		 4iilA-5x6xC:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2h CYSTATHIONINE
BETA-SYNTHASE

(Saccharomyces
cerevisiae) 		no annotation 5 SER A 225
TYR A 158
ILE A 139
GLY A 247
ASP A 249
 None
 1.43A 4iilA-6c2hA:
undetectable		 4iilA-6c2hA:
14.50