SIMILAR PATTERNS OF AMINO ACIDS FOR 4IAQ_A_2GMA2001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dju AROMATIC
AMINOTRANSFERASE


(Pyrococcus
horikoshii)
PF00155
(Aminotran_1_2)
4 ILE A 215
THR A 225
VAL A 176
SER A 217
None
1.12A 4iaqA-1djuA:
undetectable
4iaqA-1djuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ece ENDOCELLULASE E1

(Acidothermus
cellulolyticus)
PF00150
(Cellulase)
4 ILE A 111
THR A  60
VAL A  96
ASP A  45
None
1.04A 4iaqA-1eceA:
undetectable
4iaqA-1eceA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnf FIBRONECTIN

(Homo sapiens)
PF00041
(fn3)
4 ILE A1172
THR A1169
VAL A1194
SER A1225
None
1.05A 4iaqA-1fnfA:
undetectable
4iaqA-1fnfA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens)
PF00561
(Abhydrolase_1)
4 TRP A 275
ILE A 161
SER A 164
ASP A 331
None
1.10A 4iaqA-1hlgA:
undetectable
4iaqA-1hlgA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1miq PLASMEPSIN

(Plasmodium
vivax)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
ASP A 316
None
0.99A 4iaqA-1miqA:
undetectable
4iaqA-1miqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1miq PLASMEPSIN

(Plasmodium
vivax)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
SER A 261
None
0.99A 4iaqA-1miqA:
undetectable
4iaqA-1miqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n1c TORA SPECIFIC
CHAPERONE


(Shewanella
massilia)
PF02613
(Nitrate_red_del)
4 ILE A 171
THR A 175
VAL A 163
ASP A 134
None
1.02A 4iaqA-1n1cA:
2.8
4iaqA-1n1cA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nbu PROBABLE
DIHYDRONEOPTERIN
ALDOLASE


(Mycobacterium
tuberculosis)
PF02152
(FolB)
4 ILE B   5
THR B  51
VAL B  95
ASP B  82
None
1.08A 4iaqA-1nbuB:
undetectable
4iaqA-1nbuB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o0x METHIONINE
AMINOPEPTIDASE


(Thermotoga
maritima)
PF00557
(Peptidase_M24)
4 ILE A 168
VAL A 218
SER A 211
ASP A 222
None
1.16A 4iaqA-1o0xA:
0.5
4iaqA-1o0xA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1osn THYMIDINE KINASE

(Human
alphaherpesvirus
3)
PF00693
(Herpes_TK)
4 TRP A  53
ILE A  65
THR A  86
ASP A  18
BVP  A 500 (-4.6A)
BVP  A 500 ( 4.2A)
None
None
1.11A 4iaqA-1osnA:
1.0
4iaqA-1osnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1


(Rhodococcus
erythropolis)
PF00227
(Proteasome)
4 ILE H   3
THR H   1
VAL H 121
ASP H 124
None
0.86A 4iaqA-1q5rH:
0.5
4iaqA-1q5rH:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs8 PLASMEPSIN

(Plasmodium
vivax)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
SER A 261
None
1.02A 4iaqA-1qs8A:
undetectable
4iaqA-1qs8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE


(Thermotoga
maritima)
PF00793
(DAHP_synth_1)
4 ILE A  83
THR A  81
VAL A 162
ASP A 269
None
1.12A 4iaqA-1rzmA:
0.0
4iaqA-1rzmA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vko INOSITOL-3-PHOSPHATE
SYNTHASE


(Caenorhabditis
elegans)
PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5)
4 ILE A 466
THR A 492
VAL A 308
ASP A 311
None
1.17A 4iaqA-1vkoA:
0.3
4iaqA-1vkoA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vtk THYMIDINE KINASE

(Human
alphaherpesvirus
1)
PF00693
(Herpes_TK)
4 ILE A 143
THR A 350
VAL A 138
ASP A 363
None
1.13A 4iaqA-1vtkA:
2.6
4iaqA-1vtkA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aml SIS DOMAIN PROTEIN

(Listeria
monocytogenes)
PF01380
(SIS)
4 ILE A 218
THR A 216
VAL A 278
ASP A 301
None
1.17A 4iaqA-2amlA:
undetectable
4iaqA-2amlA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bju PLASMEPSIN II

(Plasmodium
falciparum)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
ASP A 316
None
0.97A 4iaqA-2bjuA:
undetectable
4iaqA-2bjuA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bju PLASMEPSIN II

(Plasmodium
falciparum)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
SER A 261
None
1.01A 4iaqA-2bjuA:
undetectable
4iaqA-2bjuA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1z UDP-GLUCOSE
FLAVONOID 3-O
GLYCOSYLTRANSFERASE


(Vitis vinifera)
PF00201
(UDPGT)
4 THR A 230
VAL A 382
SER A 221
ASP A 186
None
0.96A 4iaqA-2c1zA:
undetectable
4iaqA-2c1zA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvu THERMOPHILIC
REVERSIBLE
GAMMA-RESORCYLATE
DECARBOXYLASE


(Rhizobium sp.
MTP-10005)
PF04909
(Amidohydro_2)
4 ILE A 293
THR A 286
SER A 297
ASP A  93
None
1.01A 4iaqA-2dvuA:
undetectable
4iaqA-2dvuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gaf POLY(A) POLYMERASE
CATALYTIC SUBUNIT


(Vaccinia virus)
PF03296
(Pox_polyA_pol)
PF12629
(Pox_polyA_pol_C)
PF12630
(Pox_polyA_pol_N)
4 ILE D 229
THR D 225
VAL D 242
ASP D 202
None
1.16A 4iaqA-2gafD:
2.5
4iaqA-2gafD:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gou OXIDOREDUCTASE,
FMN-BINDING


(Shewanella
oneidensis)
PF00724
(Oxidored_FMN)
4 ILE A 249
THR A 253
SER A 283
ASP A 276
None
1.13A 4iaqA-2gouA:
undetectable
4iaqA-2gouA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hg4 6-DEOXYERYTHRONOLIDE
B SYNTHASE


(Saccharopolyspora
erythraea)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08990
(Docking)
PF16197
(KAsynt_C_assoc)
4 THR A 775
VAL A 827
SER A 705
ASP A 834
None
1.16A 4iaqA-2hg4A:
undetectable
4iaqA-2hg4A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nqa CALPAIN 8

(Homo sapiens)
PF00648
(Peptidase_C2)
4 TRP A 106
ILE A 111
THR A 115
ASP A 206
None
1.10A 4iaqA-2nqaA:
undetectable
4iaqA-2nqaA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1)
PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C)
4 TRP A 684
ILE A 687
THR A 766
ASP A 616
None
1.13A 4iaqA-2okxA:
2.6
4iaqA-2okxA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE


(Azospirillum
brasilense)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
4 THR A 236
VAL A 533
SER A 281
ASP A 382
None
1.12A 4iaqA-2q5oA:
undetectable
4iaqA-2q5oA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgy ENOLASE FROM THE
ENVIRONMENTAL GENOME
SHOTGUN SEQUENCING
OF THE SARGASSO SEA


(-)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ILE A  36
THR A  19
VAL A 361
SER A 304
None
1.11A 4iaqA-2qgyA:
undetectable
4iaqA-2qgyA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1l HYPOTHETICAL PROTEIN

(Vibrio cholerae)
PF10980
(DUF2787)
4 TRP A  72
ILE A  74
THR A   9
VAL A  42
None
1.08A 4iaqA-2v1lA:
undetectable
4iaqA-2v1lA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsu P-HYDROXYCINNAMOYL
COA HYDRATASE/LYASE


(Pseudomonas
fluorescens)
PF00378
(ECH_1)
4 TRP C   8
ILE C  23
THR C  60
ASP C  51
None
1.15A 4iaqA-2vsuC:
undetectable
4iaqA-2vsuC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1


(Homo sapiens)
PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12)
4 ILE A 329
THR A 325
VAL A 405
ASP A 369
None
1.17A 4iaqA-2xzoA:
2.4
4iaqA-2xzoA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7j PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM


(Homo sapiens)
PF00069
(Pkinase)
4 ILE A  94
THR A  92
VAL A  42
ASP A  28
None
1.17A 4iaqA-2y7jA:
2.7
4iaqA-2y7jA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ag7 PUTATIVE
UNCHARACTERIZED
PROTEIN F9E10.5


(Arabidopsis
thaliana)
no annotation 4 TRP A 583
ILE A 581
THR A 577
SER A 564
None
0.91A 4iaqA-3ag7A:
undetectable
4iaqA-3ag7A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE SMALL
SUBUNIT


(Hydrogenovibrio
marinus)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
4 ILE B  78
THR B  13
VAL B  81
ASP B  52
None
1.15A 4iaqA-3ayxB:
undetectable
4iaqA-3ayxB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn1 PEROSAMINE
SYNTHETASE


(Caulobacter
vibrioides)
PF01041
(DegT_DnrJ_EryC1)
4 ILE A 137
THR A 280
VAL A 162
ASP A 248
None
1.10A 4iaqA-3bn1A:
undetectable
4iaqA-3bn1A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cir FUMARATE REDUCTASE
IRON-SULFUR SUBUNIT


(Escherichia
coli)
PF13085
(Fer2_3)
PF13183
(Fer4_8)
4 TRP B 202
ILE B 224
THR B 174
SER B 211
None
F3S  B 245 ( 4.5A)
None
None
1.10A 4iaqA-3cirB:
undetectable
4iaqA-3cirB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyj MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN


(Rubrobacter
xylanophilus)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ILE A  35
THR A  33
VAL A 100
SER A  55
None
0.95A 4iaqA-3cyjA:
undetectable
4iaqA-3cyjA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5t MALATE DEHYDROGENASE

(Burkholderia
pseudomallei)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ILE A 267
THR A 154
VAL A 295
ASP A 195
None
1.14A 4iaqA-3d5tA:
undetectable
4iaqA-3d5tA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da0 CLEAVED CHIMERIC
RECEPTOR BINDING
PROTEIN FROM
BACTERIOPHAGES
TP901-1 AND P2


(Lactococcus
phage TP901-1;
Lactococcus
virus P2)
PF08931
(Caudo_bapla_RBP)
4 ILE A  88
THR A  80
VAL A 122
ASP A 135
None
1.17A 4iaqA-3da0A:
undetectable
4iaqA-3da0A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4f AMINOGLYCOSIDE
N3-ACETYLTRANSFERASE


(Bacillus
anthracis)
PF02522
(Antibiotic_NAT)
4 TRP A 260
ILE A 253
VAL A 223
ASP A 218
None
1.10A 4iaqA-3e4fA:
undetectable
4iaqA-3e4fA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6t ASPARTATE
AMINOTRANSFERASE


(Lactobacillus
acidophilus)
PF00155
(Aminotran_1_2)
4 ILE A 388
THR A 142
VAL A  54
ASP A  98
None
1.02A 4iaqA-3f6tA:
undetectable
4iaqA-3f6tA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D


(Homo sapiens)
PF00233
(PDEase_I)
4 ILE A 502
THR A 499
VAL A 373
ASP A 322
D71  A 901 (-4.1A)
D71  A 901 (-3.6A)
None
None
1.06A 4iaqA-3g4gA:
undetectable
4iaqA-3g4gA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kom TRANSKETOLASE

(Francisella
tularensis)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
4 ILE A 446
VAL A 459
SER A 449
ASP A 381
None
1.10A 4iaqA-3komA:
undetectable
4iaqA-3komA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8a PUTATIVE
AMINOTRANSFERASE,
PROBABLE
BETA-CYSTATHIONASE


(Streptococcus
mutans)
PF00155
(Aminotran_1_2)
4 ILE A 381
VAL A 348
SER A 383
ASP A  38
None
1.14A 4iaqA-3l8aA:
undetectable
4iaqA-3l8aA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luf TWO-COMPONENT SYSTEM
RESPONSE
REGULATOR/GGDEF
DOMAIN PROTEIN


(Aeromonas
salmonicida)
PF00072
(Response_reg)
4 ILE A  77
THR A  79
VAL A  67
ASP A  58
None
1.09A 4iaqA-3lufA:
undetectable
4iaqA-3lufA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzv DECAPRENYL
DIPHOSPHATE SYNTHASE


(Rhodobacter
capsulatus)
PF00348
(polyprenyl_synt)
4 ILE A  85
THR A  81
VAL A 150
ASP A 210
None
1.14A 4iaqA-3mzvA:
2.6
4iaqA-3mzvA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B


(Homo sapiens)
PF00233
(PDEase_I)
4 ILE A 410
THR A 407
VAL A 281
ASP A 230
ZG2  A 506 (-4.4A)
ZG2  A 506 (-4.3A)
None
None
1.09A 4iaqA-3o57A:
undetectable
4iaqA-3o57A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppc 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE


(Candida
albicans)
PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1)
4 ILE A 654
VAL A 643
SER A 656
ASP A 598
None
1.07A 4iaqA-3ppcA:
undetectable
4iaqA-3ppcA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5t FERRIC VIBRIOBACTIN
ABC TRANSPORTER,
PERIPLASMIC FERRIC
VIBRIOBACTIN-BINDING
PROTEIN


(Vibrio cholerae)
PF01497
(Peripla_BP_2)
4 ILE A 132
VAL A 119
SER A  43
ASP A 116
None
1.14A 4iaqA-3r5tA:
undetectable
4iaqA-3r5tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rn2 INTERFERON-INDUCIBLE
PROTEIN AIM2


(Homo sapiens)
PF02760
(HIN)
4 ILE A 334
THR A 301
VAL A 264
ASP A 286
None
1.13A 4iaqA-3rn2A:
undetectable
4iaqA-3rn2A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5n 4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE,
MITOCHONDRIAL


(Homo sapiens)
PF00701
(DHDPS)
4 ILE A 151
THR A 155
VAL A 180
ASP A 197
None
0.89A 4iaqA-3s5nA:
undetectable
4iaqA-3s5nA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqz PUTATIVE
HYDROXYMETHYLGLUTARY
L-COA SYNTHASE


(Streptococcus
mutans)
PF00195
(Chal_sti_synt_N)
PF08540
(HMG_CoA_synt_C)
4 ILE A  62
VAL A 162
SER A  58
ASP A  72
None
0.91A 4iaqA-3sqzA:
undetectable
4iaqA-3sqzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1w FOUR-DOMAIN
FIBRONECTIN FRAGMENT


(Homo sapiens)
PF00041
(fn3)
4 ILE A1203
THR A1200
VAL A1225
SER A1256
None
1.12A 4iaqA-3t1wA:
undetectable
4iaqA-3t1wA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tkt CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
4 ILE A  16
THR A 415
VAL A  44
ASP A 338
None
0.97A 4iaqA-3tktA:
undetectable
4iaqA-3tktA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vmn DEXTRANASE

(Streptococcus
mutans)
PF13199
(Glyco_hydro_66)
4 ILE A 450
THR A 484
VAL A 434
SER A 445
None
1.14A 4iaqA-3vmnA:
undetectable
4iaqA-3vmnA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnb PROTEIN TRANSLATION
ELONGATION FACTOR 1A


(Methanosarcina
mazei)
no annotation 4 ILE A 253
THR A 205
VAL A 189
SER A 199
None
1.10A 4iaqA-3wnbA:
undetectable
4iaqA-3wnbA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8


(Saccharomyces
cerevisiae)
PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
4 TRP B1335
ILE B1440
VAL B1361
ASP B1313
None
1.17A 4iaqA-3zefB:
undetectable
4iaqA-3zefB:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1r MANNOSYL-6-PHOSPHATA
SE


(Bacteroides
thetaiotaomicron)
PF03372
(Exo_endo_phos)
4 ILE A 194
THR A 196
VAL A 308
ASP A 225
None
0.74A 4iaqA-4c1rA:
undetectable
4iaqA-4c1rA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dzh AMIDOHYDROLASE

(Xanthomonas
campestris)
PF01979
(Amidohydro_1)
4 ILE A 312
THR A 351
VAL A 135
ASP A 379
None
0.97A 4iaqA-4dzhA:
undetectable
4iaqA-4dzhA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ehc PE-PGRS FAMILY
PROTEIN


(Mycobacterium
tuberculosis)
no annotation 4 ILE A 130
THR A 132
VAL A 115
ASP A 189
None
None
None
ZN  A 301 (-2.0A)
1.11A 4iaqA-4ehcA:
undetectable
4iaqA-4ehcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fix UDP-GALACTOFURANOSYL
TRANSFERASE GLFT2


(Mycobacterium
tuberculosis)
PF13641
(Glyco_tranf_2_3)
4 ILE A 259
THR A 349
VAL A 176
ASP A 199
None
1.15A 4iaqA-4fixA:
2.1
4iaqA-4fixA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gni PUTATIVE HEAT SHOCK
PROTEIN


(Chaetomium
thermophilum)
PF00012
(HSP70)
4 ILE A 231
THR A 220
SER A 185
ASP A 204
None
1.08A 4iaqA-4gniA:
undetectable
4iaqA-4gniA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq1 NUP37

(Schizosaccharomyces
pombe)
PF00400
(WD40)
4 ILE A 158
VAL A 146
SER A  75
ASP A 214
None
1.16A 4iaqA-4gq1A:
undetectable
4iaqA-4gq1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmb CYSTEINE SYNTHASE

(Microcystis
aeruginosa)
PF00291
(PALP)
4 ILE A 156
THR A 161
VAL A  54
ASP A   6
None
1.05A 4iaqA-4lmbA:
undetectable
4iaqA-4lmbA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4neg TRYPTOPHAN SYNTHASE
BETA CHAIN


(Bacillus
anthracis)
PF00291
(PALP)
4 ILE A 212
THR A  60
VAL A 205
SER A 380
None
1.06A 4iaqA-4negA:
undetectable
4iaqA-4negA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okd ISOAMYLASE

(Chlamydomonas
reinhardtii)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 TRP A 440
THR A 383
VAL A 200
SER A 394
None
1.11A 4iaqA-4okdA:
undetectable
4iaqA-4okdA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd4 CYTOCHROME B

(Saccharomyces
cerevisiae)
PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
4 THR C 148
VAL C 264
SER C 170
ASP C 255
None
1.11A 4iaqA-4pd4C:
4.5
4iaqA-4pd4C:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE


(Thermococcus
kodakarensis)
PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
4 ILE A 661
THR A 657
VAL B 728
SER A 509
None
1.17A 4iaqA-4qiwA:
3.8
4iaqA-4qiwA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis)
PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C)
4 ILE A  18
THR A  21
VAL A  50
SER A 180
None
1.10A 4iaqA-4qmeA:
2.7
4iaqA-4qmeA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1


(Pisum sativum)
PF00223
(PsaA_PsaB)
4 ILE A 743
THR A 746
VAL A 735
SER A 610
CLA  A1126 (-3.9A)
CL0  A9011 (-3.4A)
None
CL0  A9011 ( 4.3A)
1.14A 4iaqA-4rkuA:
2.8
4iaqA-4rkuA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s2t PROTEIN APP-1

(Caenorhabditis
elegans)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2)
4 TRP P 108
THR P 134
VAL P  66
SER P 126
None
1.03A 4iaqA-4s2tP:
undetectable
4iaqA-4s2tP:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8u LINKER L2

(Glossoscolex
paulistus)
PF00057
(Ldl_recept_a)
PF16915
(Eryth_link_C)
4 ILE N 158
VAL N 217
SER N 160
ASP N 203
None
1.13A 4iaqA-4u8uN:
undetectable
4iaqA-4u8uN:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wat PFRH5

(Plasmodium
falciparum)
no annotation 4 ILE A 157
VAL A 174
SER A 153
ASP A 218
None
1.08A 4iaqA-4watA:
5.3
4iaqA-4watA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wlh KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 1


(Homo sapiens)
PF00155
(Aminotran_1_2)
4 ILE A 229
THR A 239
VAL A 190
SER A 231
None
1.04A 4iaqA-4wlhA:
undetectable
4iaqA-4wlhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wp0 KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 1


(Homo sapiens)
PF00155
(Aminotran_1_2)
4 ILE A 229
THR A 239
VAL A 190
SER A 231
None
0.90A 4iaqA-4wp0A:
undetectable
4iaqA-4wp0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9x DEGV
DOMAIN-CONTAINING
PROTEIN MW1315


(Staphylococcus
aureus)
PF02645
(DegV)
4 ILE A 263
THR A 260
VAL A 158
SER A 119
OLA  A 301 ( 3.7A)
None
None
OLA  A 301 ( 3.3A)
1.12A 4iaqA-4x9xA:
undetectable
4iaqA-4x9xA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeb FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 3


(Mus musculus)
PF13855
(LRR_8)
4 ILE B 190
VAL B 205
SER B 194
ASP B 184
None
1.09A 4iaqA-4yebB:
undetectable
4iaqA-4yebB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypg INTERFERON ALPHA-2

(Homo sapiens)
PF00143
(Interferon)
4 TRP C  76
THR C  14
VAL C 142
SER C 152
None
1.09A 4iaqA-4ypgC:
undetectable
4iaqA-4ypgC:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwy PLASMEPSIN-2

(Plasmodium
falciparum)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
ASP A 316
None
0.91A 4iaqA-5bwyA:
undetectable
4iaqA-5bwyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwy PLASMEPSIN-2

(Plasmodium
falciparum)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
SER A 261
None
0.96A 4iaqA-5bwyA:
undetectable
4iaqA-5bwyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey2 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY


(Bacillus cereus)
PF06018
(CodY)
PF08222
(HTH_CodY)
4 ILE A 113
THR A 125
VAL A  91
SER A  78
None
0.99A 4iaqA-5ey2A:
undetectable
4iaqA-5ey2A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7v LMO0181 PROTEIN

(Listeria
monocytogenes)
PF01547
(SBP_bac_1)
4 ILE A 211
THR A 219
VAL A 203
SER A 407
None
1.03A 4iaqA-5f7vA:
undetectable
4iaqA-5f7vA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fft PULMONARY
SURFACTANT-ASSOCIATE
D PROTEIN A


(Rattus
norvegicus)
PF00059
(Lectin_C)
4 ILE A 131
THR A 130
VAL A 144
ASP A 182
None
1.12A 4iaqA-5fftA:
undetectable
4iaqA-5fftA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE


(Pyrococcus
horikoshii)
PF02449
(Glyco_hydro_42)
4 ILE A  95
THR A 177
VAL A  21
ASP A   9
None
0.90A 4iaqA-5gslA:
undetectable
4iaqA-5gslA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i70 PLASMEPSIN IV

(Plasmodium
falciparum)
no annotation 4 TRP B 193
ILE B 195
VAL B 312
SER B 261
None
1.07A 4iaqA-5i70B:
undetectable
4iaqA-5i70B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5igq E3 UBIQUITIN-PROTEIN
LIGASE RFWD2


(Homo sapiens)
PF00400
(WD40)
4 ILE A 473
VAL A 495
SER A 426
ASP A 535
None
1.06A 4iaqA-5igqA:
undetectable
4iaqA-5igqA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jod PROPLASMEPSIN IV

(Plasmodium
falciparum)
PF00026
(Asp)
4 TRP A 193
ILE A 195
VAL A 312
SER A 261
None
0.95A 4iaqA-5jodA:
undetectable
4iaqA-5jodA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kci UNCHARACTERIZED
PROTEIN YPL067C


(Saccharomyces
cerevisiae)
PF12239
(DUF3605)
4 ILE A 190
THR A 186
VAL A 106
ASP A  93
None
1.13A 4iaqA-5kciA:
undetectable
4iaqA-5kciA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l56 PLEXIN-A1

(Mus musculus)
PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG)
4 ILE A 484
THR A 433
SER A 452
ASP A 527
None
1.14A 4iaqA-5l56A:
undetectable
4iaqA-5l56A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l94 CYTOCHROME P450

(Bacillus
megaterium)
PF00067
(p450)
4 ILE A 251
THR A 254
VAL A 144
ASP A 166
None
1.16A 4iaqA-5l94A:
undetectable
4iaqA-5l94A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohj CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B


(Homo sapiens)
no annotation 4 ILE A 582
THR A 579
VAL A 453
ASP A 402
9VE  A 801 (-4.1A)
9VE  A 801 (-4.1A)
None
None
1.05A 4iaqA-5ohjA:
undetectable
4iaqA-5ohjA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v12 HERCYNYLCYSTEINE
SULFOXIDE LYASE


(Neurospora
crassa)
no annotation 4 ILE C 268
THR C 112
VAL C 262
ASP C 237
None
1.08A 4iaqA-5v12C:
undetectable
4iaqA-5v12C:
12.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B


(Homo sapiens;
Spodoptera
frugiperda)
no annotation 6 TRP A 125
ILE A 130
THR A 134
VAL A 200
SER A 212
ASP A 352
None
89F  A1201 (-4.3A)
89F  A1201 (-4.2A)
None
89F  A1201 ( 3.8A)
None
0.85A 4iaqA-5v54A:
39.9
4iaqA-5v54A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbl REGULATORY-ASSOCIATE
D PROTEIN OF TOR 1


(Arabidopsis
thaliana)
no annotation 4 ILE A 694
VAL A 714
SER A 696
ASP A 626
None
1.06A 4iaqA-5wblA:
2.9
4iaqA-5wblA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbf HARMONIN
UNCONVENTIONAL
MYOSIN-VIIB


(Homo sapiens)
PF00373
(FERM_M)
PF00595
(PDZ)
PF00784
(MyTH4)
4 ILE A2038
THR A2006
VAL A2025
ASP B 547
None
1.03A 4iaqA-5xbfA:
undetectable
4iaqA-5xbfA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi UNCHARACTERIZED
PROTEIN


(Trichomonas
vaginalis)
PF00366
(Ribosomal_S17)
PF16205
(Ribosomal_S17_N)
4 ILE L 105
THR L 103
VAL L 137
ASP L 119
None
U  2 238 ( 2.8A)
None
None
1.13A 4iaqA-5xyiL:
undetectable
4iaqA-5xyiL:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yid PLASMEPSIN II

(Plasmodium
falciparum)
no annotation 4 TRP A 195
ILE A 197
VAL A 314
SER A 263
None
0.93A 4iaqA-5yidA:
undetectable
4iaqA-5yidA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywp JEV E PROTEIN

(Japanese
encephalitis
virus)
no annotation 4 ILE A  33
THR A  40
VAL A  24
ASP A  28
None
1.12A 4iaqA-5ywpA:
undetectable
4iaqA-5ywpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bqh 5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562


(Escherichia
coli;
Homo sapiens)
no annotation 4 TRP A 130
THR A 139
VAL A 208
SER A 219
None
E2J  A1201 (-4.3A)
None
E2J  A1201 (-3.2A)
0.90A 4iaqA-6bqhA:
32.0
4iaqA-6bqhA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1


(Cyanidioschyzon
merolae)
no annotation 4 ILE A 733
THR A 736
VAL A 725
SER A 600
CLA  A1126 ( 3.8A)
CLA  A1011 (-3.1A)
None
CLA  A1011 ( 4.3A)
1.09A 4iaqA-6fosA:
2.9
4iaqA-6fosA:
11.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6g79 5-HYDROXYTRYPTAMINE
RECEPTOR 1B


(Homo sapiens)
no annotation 4 TRP S 125
ILE S 130
THR S 134
SER S 212
None
EP5  S 401 (-4.2A)
EP5  S 401 (-3.8A)
EP5  S 401 (-3.3A)
0.72A 4iaqA-6g79S:
34.2
4iaqA-6g79S:
95.18