SIMILAR PATTERNS OF AMINO ACIDS FOR 4I13_A_FOLA201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cz3 | DIHYDROFOLATEREDUCTASE (Thermotogamaritima) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 58THR A 121 | None | 0.35A | 4i13A-1cz3A:19.9 | 4i13A-1cz3A:29.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq1 | CYTOCHROME CD1NITRITE REDUCTASE (Paracoccuspantotrophus) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 3 | ASP A 175ARG A 243THR A 552 | NoneDHE A 602 (-3.9A)None | 0.74A | 4i13A-1gq1A:undetectable | 4i13A-1gq1A:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz0 | HYPOTHETICALTRNA/RRNAMETHYLTRANSFERASEYJFH (Escherichiacoli) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 3 | ASP A 101ARG A 153THR A 206 | None | 0.84A | 4i13A-1gz0A:undetectable | 4i13A-1gz0A:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 3 | ASP A 92ARG A 53THR A 113 | None | 0.83A | 4i13A-1hwnA:undetectable | 4i13A-1hwnA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9g | HYPOTHETICAL PROTEINRV2118C (Mycobacteriumtuberculosis) |
PF08704(GCD14)PF14801(GCD14_N) | 3 | ASP A 87ARG A 226THR A 252 | None | 0.88A | 4i13A-1i9gA:2.6 | 4i13A-1i9gA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpx | ALPHA-AMINO ACIDESTER HYDROLASE (Xanthomonascitri) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 3 | ASP A 145ARG A 292THR A 148 | None | 0.68A | 4i13A-1mpxA:undetectable | 4i13A-1mpxA:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qc5 | PROTEIN (ALPHA1BETA1 INTEGRIN) (Homo sapiens) |
PF00092(VWA) | 3 | ASP B 340ARG B 477THR B 410 | MG B 602 ( 4.5A)None MG B 602 ( 4.8A) | 0.87A | 4i13A-1qc5B:undetectable | 4i13A-1qc5B:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qh4 | CREATINE KINASE (Gallus gallus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 3 | ASP A 78ARG A 209THR A 47 | None | 0.83A | 4i13A-1qh4A:undetectable | 4i13A-1qh4A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu2 | ISOLEUCYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF00133(tRNA-synt_1)PF06827(zf-FPG_IleRS)PF08264(Anticodon_1) | 3 | ASP A 95ARG A 455THR A 154 | MRC A1993 ( 4.7A)NoneNone | 0.85A | 4i13A-1qu2A:undetectable | 4i13A-1qu2A:9.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2k | MOLYBDENUM COFACTORBIOSYNTHESIS PROTEINB (Escherichiacoli) |
no annotation | 3 | ASP B 26ARG B 143THR B 16 | None | 0.65A | 4i13A-1r2kB:undetectable | 4i13A-1r2kB:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqg | METHIONYL-TRNASYNTHETASE (Pyrococcusabyssi) |
PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 3 | ASP A 50ARG A 231THR A 95 | None | 0.79A | 4i13A-1rqgA:undetectable | 4i13A-1rqgA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6r | CREATINE KINASE, MCHAIN (Oryctolaguscuniculus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 3 | ASP A 77ARG A 208THR A 46 | None | 0.84A | 4i13A-1u6rA:undetectable | 4i13A-1u6rA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vj0 | ALCOHOLDEHYDROGENASE,ZINC-CONTAINING (Thermotogamaritima) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | ASP A 148ARG A 125THR A 317 | None | 0.85A | 4i13A-1vj0A:2.6 | 4i13A-1vj0A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8o | BACTERIAL SIALIDASE (Micromonosporaviridifaciens) |
PF00754(F5_F8_type_C)PF10633(NPCBM_assoc)PF13088(BNR_2) | 3 | ASP A 259ARG A 68THR A 226 | GOL A1651 (-2.8A)CIT A1649 ( 2.6A)None | 0.87A | 4i13A-1w8oA:undetectable | 4i13A-1w8oA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdu | TRAS1 ORF2P (Bombyx mori) |
PF14529(Exo_endo_phos_2) | 3 | ASP A 211ARG A 173THR A 196 | None | 0.87A | 4i13A-1wduA:undetectable | 4i13A-1wduA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y5e | MOLYBDENUM COFACTORBIOSYNTHESIS PROTEINB (Bacillus cereus) |
PF00994(MoCF_biosynth) | 3 | ASP A 30ARG A 148THR A 20 | None | 0.65A | 4i13A-1y5eA:undetectable | 4i13A-1y5eA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3q | THAUMATIN-LIKEPROTEIN (Musa acuminata) |
PF00314(Thaumatin) | 3 | ASP A 180ARG A 169THR A 184 | NoneEDO A 901 (-4.3A)None | 0.83A | 4i13A-1z3qA:undetectable | 4i13A-1z3qA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zca | G ALPHA I/12 (Mus musculus) |
PF00503(G-alpha) | 3 | ASP A 297ARG A 168THR A 350 | GDP A 382 (-3.1A)NoneGDP A 382 (-3.7A) | 0.89A | 4i13A-1zcaA:undetectable | 4i13A-1zcaA:18.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zdr | DIHYDROFOLATEREDUCTASE (Geobacillusstearothermophilus) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 57THR A 115 | NoneSO4 A3484 (-3.3A)None | 0.31A | 4i13A-1zdrA:23.6 | 4i13A-1zdrA:40.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azq | CATECHOL1,2-DIOXYGENASE (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 3 | ASP A 127ARG A 176THR A 158 | None | 0.87A | 4i13A-2azqA:undetectable | 4i13A-2azqA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2blb | DIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumvivax) |
PF00186(DHFR_1) | 3 | ASP A 53ARG A 131THR A 194 | CP7 A1240 (-3.1A)MES A1241 (-2.7A)CP7 A1240 (-4.1A) | 0.30A | 4i13A-2blbA:19.0 | 4i13A-2blbA:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8t | ARGONAUTE PROTEIN (Aquifexaeolicus) |
PF02171(Piwi) | 3 | ASP A 577ARG A 644THR A 544 | None | 0.83A | 4i13A-2f8tA:undetectable | 4i13A-2f8tA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fgq | OUTER MEMBRANE PORINPROTEIN 32 (Delftiaacidovorans) |
PF13609(Porin_4) | 3 | ASP X 129ARG X 92THR X 194 | None | 0.88A | 4i13A-2fgqX:undetectable | 4i13A-2fgqX:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 3 | ASP A 48ARG A 94THR A 178 | None | 0.18A | 4i13A-2h2qA:18.4 | 4i13A-2h2qA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi0 | PUTATIVEPHOSPHOGLYCOLATEPHOSPHATASE (Lactobacillusdelbrueckii) |
PF13419(HAD_2) | 3 | ASP A 11ARG A 57THR A 17 | None | 0.84A | 4i13A-2hi0A:undetectable | 4i13A-2hi0A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hz7 | GLUTAMINYL-TRNASYNTHETASE (Deinococcusradiodurans) |
PF00749(tRNA-synt_1c)PF03950(tRNA-synt_1c_C) | 3 | ASP A 375ARG A 428THR A 343 | None | 0.83A | 4i13A-2hz7A:undetectable | 4i13A-2hz7A:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2is8 | MOLYBDOPTERINBIOSYNTHESIS ENZYME,MOAB (Thermusthermophilus) |
PF00994(MoCF_biosynth) | 3 | ASP A 20ARG A 136THR A 8 | FMT A1003 (-3.7A)NoneFMT A1003 (-4.1A) | 0.71A | 4i13A-2is8A:undetectable | 4i13A-2is8A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv2 | FORMATEDEHYDROGENASE H (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 3 | ASP X 343ARG X 138THR X 456 | None | 0.86A | 4i13A-2iv2X:undetectable | 4i13A-2iv2X:12.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgd | 2-OXOGLUTARATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00676(E1_dh)PF02779(Transket_pyr)PF16870(OxoGdeHyase_C) | 3 | ASP A 451ARG A 261THR A 409 | None | 0.75A | 4i13A-2jgdA:undetectable | 4i13A-2jgdA:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oip | CHAIN A, CRYSTALSTRUCTURE OF DHFR (Cryptosporidiumhominis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 3 | ASP A 32ARG A 70THR A 134 | MTX A 605 ( 3.0A)MTX A 605 ( 3.1A)MTX A 605 ( 4.2A) | 0.22A | 4i13A-2oipA:19.7 | 4i13A-2oipA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vmf | BETA-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2) | 3 | ASP A 660ARG A 823THR A 566 | None | 0.51A | 4i13A-2vmfA:undetectable | 4i13A-2vmfA:11.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w3w | DIHYDROFOLATEREDUCTASE (Mycobacteriumavium) |
PF00186(DHFR_1) | 3 | ASP A 31ARG A 64THR A 121 | VG9 A1168 (-3.0A)VG9 A1168 ( 3.7A)VG9 A1168 ( 4.7A) | 0.65A | 4i13A-2w3wA:23.1 | 4i13A-2w3wA:34.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w9s | DIHYDROFOLATEREDUCTASE TYPE 1FROM TN4003 (Staphylococcusaureus) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 57THR A 111 | TOP A1160 (-2.8A)NoneTOP A1160 ( 4.5A) | 0.51A | 4i13A-2w9sA:23.7 | 4i13A-2w9sA:38.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yd0 | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 3 | ASP A 195ARG A 430THR A 244 | None | 0.74A | 4i13A-2yd0A:undetectable | 4i13A-2yd0A:9.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zws | NEUTRAL CERAMIDASE (Pseudomonasaeruginosa) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 3 | ASP A 218ARG A 160THR A 269 | None ZN A 647 ( 4.3A)None | 0.73A | 4i13A-2zwsA:undetectable | 4i13A-2zwsA:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3i | PENICILLIN-BINDINGPROTEIN 4 (Haemophilusinfluenzae) |
PF02113(Peptidase_S13) | 3 | ASP A 257ARG A 154THR A 146 | None | 0.90A | 4i13A-3a3iA:undetectable | 4i13A-3a3iA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT AGLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNITC,LINKER,GLUTAMATE--TRNA LIGASE 2 (Thermotogamaritima;Thermotogamaritima;syntheticconstruct) |
PF01425(Amidase)PF00749(tRNA-synt_1c)PF02686(Glu-tRNAGln) | 3 | ASP A 221ARG C 69THR A 93 | None | 0.89A | 4i13A-3al0A:undetectable | 4i13A-3al0A:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ch0 | GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE (Cytophagahutchinsonii) |
PF03009(GDPD) | 3 | ASP A 219ARG A 102THR A 221 | EDO A 275 ( 2.7A)GOL A 289 (-2.7A)EDO A 274 (-3.0A) | 0.87A | 4i13A-3ch0A:undetectable | 4i13A-3ch0A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctp | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Alkaliphilusmetalliredigens) |
PF13377(Peripla_BP_3) | 3 | ASP A 240ARG A 124THR A 281 | NoneXLF A 401 (-4.0A)None | 0.80A | 4i13A-3ctpA:undetectable | 4i13A-3ctpA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfr | DIHYDROFOLATEREDUCTASE (Lactobacilluscasei) |
PF00186(DHFR_1) | 3 | ASP A 26ARG A 57THR A 116 | MTX A 164 ( 2.9A)MTX A 164 ( 2.9A)MTX A 164 ( 4.3A) | 0.32A | 4i13A-3dfrA:22.6 | 4i13A-3dfrA:29.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dg8 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00186(DHFR_1) | 3 | ASP A 54ARG A 122THR A 185 | RJ6 A 609 (-3.0A)NoneRJ6 A 609 ( 4.5A) | 0.24A | 4i13A-3dg8A:19.2 | 4i13A-3dg8A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3m | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Ruegeriapomeroyi) |
PF13377(Peripla_BP_3) | 3 | ASP A 257ARG A 200THR A 298 | None | 0.89A | 4i13A-3e3mA:2.4 | 4i13A-3e3mA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3exs | RMPD(HEXULOSE-6-PHOSPHATE SYNTHASE) (Streptococcusmutans) |
PF00215(OMPdecase) | 3 | ASP A 64ARG A 144THR A 87 | 5RP A 501 ( 4.8A)NoneNone | 0.89A | 4i13A-3exsA:undetectable | 4i13A-3exsA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3git | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica) |
PF03598(CdhC) | 3 | ASP A 497ARG A 685THR A 521 | None | 0.77A | 4i13A-3gitA:undetectable | 4i13A-3gitA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gka | N-ETHYLMALEIMIDEREDUCTASE (Burkholderiapseudomallei) |
PF00724(Oxidored_FMN) | 3 | ASP A 245ARG A 112THR A 251 | None | 0.82A | 4i13A-3gkaA:undetectable | 4i13A-3gkaA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHA (Moorellathermoacetica) |
PF03598(CdhC) | 3 | ASP M 497ARG M 685THR M 521 | None | 0.89A | 4i13A-3i04M:undetectable | 4i13A-3i04M:12.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3i8a | DIHYDROFOLATEREDUCTASE (Staphylococcusaureus) |
PF00186(DHFR_1) | 3 | ASP X 27ARG X 57THR X 111 | N22 X 219 (-2.8A)NoneN22 X 219 (-4.4A) | 0.45A | 4i13A-3i8aX:23.9 | 4i13A-3i8aX:37.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju5 | ARGININE KINASE (Apostichopusjaponicus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 3 | ASP A 69ARG A 199THR A 42 | None | 0.88A | 4i13A-3ju5A:undetectable | 4i13A-3ju5A:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 3 | ASP A 37ARG A 83THR A 144 | None | 0.19A | 4i13A-3kjrA:19.8 | 4i13A-3kjrA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjd | OROTATEPHOSPHORIBOSYLTRANSFERASE (Francisellatularensis) |
PF00156(Pribosyltran) | 3 | ASP A 150ARG A 203THR A 163 | None | 0.67A | 4i13A-3mjdA:undetectable | 4i13A-3mjdA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olo | TWO-COMPONENT SENSORHISTIDINE KINASE (Nostoc sp. PCC7120) |
PF00989(PAS) | 3 | ASP A 59ARG A 71THR A 80 | None | 0.77A | 4i13A-3oloA:undetectable | 4i13A-3oloA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oyz | MALATE SYNTHASE (Haloferaxvolcanii) |
PF03328(HpcH_HpaI) | 3 | ASP A 188ARG A 89THR A 216 | None | 0.68A | 4i13A-3oyzA:undetectable | 4i13A-3oyzA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qbd | 3-DEHYDROQUINATESYNTHASE (Mycobacteriumtuberculosis) |
PF01761(DHQ_synthase) | 3 | ASP A 168ARG A 58THR A 171 | NoneNoneNAD A 400 (-4.9A) | 0.82A | 4i13A-3qbdA:undetectable | 4i13A-3qbdA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg9 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomabrucei) |
PF00186(DHFR_1) | 3 | ASP A 54ARG A 100THR A 184 | WRA A 602 (-2.9A)NoneWRA A 602 (-4.2A) | 0.28A | 4i13A-3rg9A:18.3 | 4i13A-3rg9A:27.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpd | METHIONINE SYNTHASE(B12-INDEPENDENT) (Shewanella sp.W3-18-1) |
PF01717(Meth_synt_2) | 3 | ASP A 125ARG A 117THR A 75 | None | 0.38A | 4i13A-3rpdA:undetectable | 4i13A-3rpdA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlm | SARCOPLASMIC/ENDOPLASMIC RETICULUMCALCIUM ATPASE 1 (Bos taurus) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF08282(Hydrolase_3)PF13246(Cation_ATPase) | 3 | ASP A 600ARG A 677THR A 357 | NoneACP A1001 (-3.3A)None | 0.64A | 4i13A-3tlmA:undetectable | 4i13A-3tlmA:9.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tq9 | DIHYDROFOLATEREDUCTASE (Coxiellaburnetii) |
PF00186(DHFR_1) | 3 | ASP A 28ARG A 58THR A 115 | MTX A2001 (-2.7A)MTX A2001 (-2.8A)MTX A2001 (-4.3A) | 0.25A | 4i13A-3tq9A:23.7 | 4i13A-3tq9A:43.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3um6 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 3 | ASP A 54ARG A 122THR A 185 | 1CY A 609 (-2.9A)None1CY A 609 (-4.3A) | 0.25A | 4i13A-3um6A:19.2 | 4i13A-3um6A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vco | DIHYDROFOLATEREDUCTASE (Schistosomamansoni) |
PF00186(DHFR_1) | 3 | ASP A 28ARG A 67THR A 133 | None | 0.17A | 4i13A-3vcoA:18.8 | 4i13A-3vcoA:29.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w53 | BETA-GLUCOSIDASE (Micrococcusantarcticus) |
PF00232(Glyco_hydro_1) | 3 | ASP A 303ARG A 344THR A 227 | None | 0.83A | 4i13A-3w53A:undetectable | 4i13A-3w53A:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zh4 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 3 | ASP A 326ARG A 92THR A 297 | NoneFLC A1419 ( 4.0A)None | 0.74A | 4i13A-3zh4A:undetectable | 4i13A-3zh4A:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 3 | ASP A 421ARG A 101THR A 48 | None | 0.90A | 4i13A-4a5qA:undetectable | 4i13A-4a5qA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ab4 | XENOBIOTIC REDUCTASEB (Pseudomonasputida) |
PF00724(Oxidored_FMN) | 3 | ASP A 237ARG A 104THR A 243 | None | 0.89A | 4i13A-4ab4A:undetectable | 4i13A-4ab4A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bin | N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC (Escherichiacoli) |
PF01520(Amidase_3)PF11741(AMIN) | 3 | ASP A 95ARG A 102THR A 48 | None | 0.71A | 4i13A-4binA:2.1 | 4i13A-4binA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckb | MRNA-CAPPING ENZYMECATALYTIC SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL)PF10640(Pox_ATPase-GT) | 3 | ASP A 545ARG A 748THR A 653 | None | 0.86A | 4i13A-4ckbA:2.8 | 4i13A-4ckbA:9.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dbg | RANBP-TYPE ANDC3HC4-TYPE ZINCFINGER-CONTAININGPROTEIN 1RING FINGER PROTEIN31 (Homo sapiens;Homo sapiens) |
no annotationPF16678(HOIP-UBA) | 3 | ASP A 91ARG A 76THR B 610 | None | 0.89A | 4i13A-4dbgA:undetectable | 4i13A-4dbgA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl9 | TYROSINE-PROTEINKINASE (Mus musculus) |
PF07714(Pkinase_Tyr) | 3 | ASP A 873ARG A 847THR A 875 | None | 0.77A | 4i13A-4gl9A:undetectable | 4i13A-4gl9A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 3 | ASP A 209ARG A 32THR A 225 | None | 0.70A | 4i13A-4j9uA:undetectable | 4i13A-4j9uA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kbm | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Mycobacteriumtuberculosis) |
PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1) | 3 | ASP A 259ARG A 224THR A 229 | None | 0.80A | 4i13A-4kbmA:undetectable | 4i13A-4kbmA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lrs | ACETALDEHYDEDEHYDROGENASE (Thermomonosporacurvata) |
PF01118(Semialdhyde_dh)PF09290(AcetDehyd-dimer) | 3 | ASP B 37ARG B 284THR B 301 | None | 0.89A | 4i13A-4lrsB:2.3 | 4i13A-4lrsB:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lu6 | FLAVIN-DEPENDENTTRYPTOPHANHALOGENASE REBH (Lechevalieriaaerocolonigenes) |
PF04820(Trp_halogenase) | 3 | ASP A 195ARG A 231THR A 215 | None | 0.83A | 4i13A-4lu6A:undetectable | 4i13A-4lu6A:14.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4m2x | DIHYDROFOLATEREDUCTASE (Mycobacteriumtuberculosis) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 60THR A 113 | TMQ A 202 ( 2.7A)NoneTMQ A 202 (-4.2A) | 0.39A | 4i13A-4m2xA:21.5 | 4i13A-4m2xA:35.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4m7v | DIHYDROFOLATEREDUCTASE (Enterococcusfaecalis) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 58THR A 116 | RAR A 200 (-2.6A)RAR A 200 ( 3.2A)RAR A 200 (-4.4A) | 0.52A | 4i13A-4m7vA:23.0 | 4i13A-4m7vA:37.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6m | AF2299, ACDP-ALCOHOLPHOSPHOTRANSFERASE (Archaeoglobusfulgidus) |
PF01066(CDP-OH_P_transf) | 3 | ASP A 235ARG A 304THR A 178 | CA A 401 (-2.2A)SO4 A 411 (-2.6A)None | 0.76A | 4i13A-4o6mA:undetectable | 4i13A-4o6mA:18.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p68 | DIHYDROFOLATEREDUCTASE (Escherichiacoli) |
PF00186(DHFR_1) | 3 | ASP A 27ARG A 57THR A 113 | MTX A 201 (-3.0A)MTX A 201 (-3.0A)MTX A 201 ( 4.5A) | 0.25A | 4i13A-4p68A:28.3 | 4i13A-4p68A:98.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uy6 | HISTIDINE-SPECIFICMETHYLTRANSFERASEEGTD (Mycolicibacteriumsmegmatis) |
PF10017(Methyltransf_33) | 3 | ASP A 48ARG A 60THR A 89 | None | 0.66A | 4i13A-4uy6A:2.9 | 4i13A-4uy6A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wgk | NEUTRAL CERAMIDASE (Homo sapiens) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 3 | ASP A 317ARG A 257THR A 397 | None ZN A 801 ( 4.5A)None | 0.71A | 4i13A-4wgkA:undetectable | 4i13A-4wgkA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bs5 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 3 | ASP A 361ARG A 710THR A 408 | None | 0.88A | 4i13A-5bs5A:undetectable | 4i13A-5bs5A:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1k | GEM-ASSOCIATEDPROTEIN 5 (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 3 | ASP A 696ARG A 6THR A 712 | None | 0.89A | 4i13A-5h1kA:undetectable | 4i13A-5h1kA:12.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjr | NEUTRALALPHA-GLUCOSIDASE AB (Mus musculus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 3 | ASP A 870ARG A 482THR A 873 | None | 0.85A | 4i13A-5hjrA:undetectable | 4i13A-5hjrA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iva | LPS-ASSEMBLY PROTEINLPTD (Pseudomonasaeruginosa) |
PF04453(OstA_C) | 3 | ASP A 596ARG A 86THR A 199 | None | 0.86A | 4i13A-5ivaA:undetectable | 4i13A-5ivaA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jo7 | VETISPIRADIENESYNTHASE 1 (Hyoscyamusmuticus) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | ASP A 451ARG A 273THR A 455 | None | 0.80A | 4i13A-5jo7A:undetectable | 4i13A-5jo7A:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kiv | PROTEIN-ADP-RIBOSEHYDROLASE (Staphylococcusaureus) |
PF01661(Macro) | 3 | ASP A 93ARG A 42THR A 96 | None | 0.85A | 4i13A-5kivA:undetectable | 4i13A-5kivA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mb4 | GLCNAC SPECIFICLECTIN (Psathyrella) |
PF13517(VCBS) | 3 | ASP A 69ARG A 33THR A 67 | NA A 505 ( 3.0A)None NA A 505 (-2.9A) | 0.88A | 4i13A-5mb4A:undetectable | 4i13A-5mb4A:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o25 | TMPDE (Thermotogamaritima) |
no annotation | 3 | ASP A 80ARG A 267THR A 124 | MN A 401 ( 2.6A)PG4 A 403 ( 3.6A)None | 0.78A | 4i13A-5o25A:undetectable | 4i13A-5o25A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0l | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Toxoplasmagondii) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 3 | ASP A 31ARG A 97THR A 172 | 73X A 704 (-2.8A)None73X A 704 (-4.2A) | 0.20A | 4i13A-5t0lA:19.9 | 4i13A-5t0lA:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usf | TYROSYL-TRNASYNTHETASE, PUTATIVE (Leishmaniadonovani) |
PF00579(tRNA-synt_1b) | 3 | ASP A 263ARG A 272THR A 147 | None | 0.72A | 4i13A-5usfA:undetectable | 4i13A-5usfA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5via | PSEUDOPEROXIDASE (Leishmaniamajor) |
PF00141(peroxidase) | 3 | ASP A 104ARG A 252THR A 265 | None | 0.77A | 4i13A-5viaA:undetectable | 4i13A-5viaA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x9w | DNA MISMATCH REPAIRPROTEIN MUTS (Neisseriagonorrhoeae) |
no annotation | 3 | ASP A 644ARG A 270THR A 678 | None | 0.87A | 4i13A-5x9wA:undetectable | 4i13A-5x9wA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yfb | DIPEPTIDYL PEPTIDASE3 (Armillariatabescens) |
no annotation | 3 | ASP A 489ARG A 394THR A 312 | None | 0.61A | 4i13A-5yfbA:undetectable | 4i13A-5yfbA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z4i | UBIQUITINCARBOXYL-TERMINALHYDROLASE 20 (Homo sapiens) |
no annotation | 3 | ASP A 59ARG A 80THR A 62 | None | 0.84A | 4i13A-5z4iA:undetectable | 4i13A-5z4iA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zm4 | DIOXYGENASE ANDA (Aspergillusstellatus) |
no annotation | 3 | ASP A 281ARG A 247THR A 265 | None | 0.85A | 4i13A-5zm4A:undetectable | 4i13A-5zm4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bgd | GLUCOSE/GALACTOSE-BINDING LIPOPROTEIN (Treponemapallidum) |
no annotation | 3 | ASP A 173ARG A 285THR A 212 | None | 0.84A | 4i13A-6bgdA:undetectable | 4i13A-6bgdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chs | PUTATIVE CELLDIVISION CONTROLPROTEIN (Chaetomiumthermophilum) |
no annotation | 3 | ASP H 320ARG H 365THR H 268 | MG H 903 (-3.1A)None MG H 903 ( 3.5A) | 0.89A | 4i13A-6chsH:undetectable | 4i13A-6chsH:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxd | PEPTIDASE B (Yersinia pestis) |
no annotation | 3 | ASP A 397ARG A 403THR A 307 | NoneNoneSO4 A 503 (-4.6A) | 0.74A | 4i13A-6cxdA:undetectable | 4i13A-6cxdA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxm | DIHYDROFOLATEREDUCTASE (Mycolicibacteriumsmegmatis) |
no annotation | 3 | ASP A 28ARG A 61THR A 111 | MMV A 202 (-2.9A)MMV A 202 (-2.8A)MMV A 202 (-4.4A) | 0.34A | 4i13A-6cxmA:20.1 | 4i13A-6cxmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e4e | - (-) |
no annotation | 3 | ASP A 27ARG A 57THR A 111 | MMV A 202 (-2.9A)NoneMMV A 202 (-4.3A) | 0.40A | 4i13A-6e4eA:23.8 | 4i13A-6e4eA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6enz | ACIDIC AMINO ACIDDECARBOXYLASE GADL1 (Mus musculus) |
no annotation | 3 | ASP A 107ARG A 392THR A 377 | None | 0.81A | 4i13A-6enzA:undetectable | 4i13A-6enzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 3 | ASP A1252ARG A 506THR A 34 | None | 0.86A | 4i13A-6eojA:undetectable | 4i13A-6eojA:8.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f91 | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 3 | ASP A 76ARG A 43THR A 64 | None | 0.87A | 4i13A-6f91A:undetectable | 4i13A-6f91A:undetectable |