SIMILAR PATTERNS OF AMINO ACIDS FOR 4I13_A_FOLA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz3 DIHYDROFOLATE
REDUCTASE

(Thermotoga
maritima) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  58
THR A 121
 None
 0.35A 4i13A-1cz3A:
19.9		 4i13A-1cz3A:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq1 CYTOCHROME CD1
NITRITE REDUCTASE

(Paracoccus
pantotrophus) 		PF02239
(Cytochrom_D1)
PF13442
(Cytochrome_CBB3) 		3 ASP A 175
ARG A 243
THR A 552
 None
DHE  A 602 (-3.9A)
None
 0.74A 4i13A-1gq1A:
undetectable		 4i13A-1gq1A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz0 HYPOTHETICAL
TRNA/RRNA
METHYLTRANSFERASE
YJFH

(Escherichia
coli) 		PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind) 		3 ASP A 101
ARG A 153
THR A 206
 None
 0.84A 4i13A-1gz0A:
undetectable		 4i13A-1gz0A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hwn EBULIN

(Sambucus ebulus) 		PF00161
(RIP) 		3 ASP A  92
ARG A  53
THR A 113
 None
 0.83A 4i13A-1hwnA:
undetectable		 4i13A-1hwnA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i9g HYPOTHETICAL PROTEIN
RV2118C

(Mycobacterium
tuberculosis) 		PF08704
(GCD14)
PF14801
(GCD14_N) 		3 ASP A  87
ARG A 226
THR A 252
 None
 0.88A 4i13A-1i9gA:
2.6		 4i13A-1i9gA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpx ALPHA-AMINO ACID
ESTER HYDROLASE

(Xanthomonas
citri) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		3 ASP A 145
ARG A 292
THR A 148
 None
 0.68A 4i13A-1mpxA:
undetectable		 4i13A-1mpxA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qc5 PROTEIN (ALPHA1
BETA1 INTEGRIN)

(Homo sapiens) 		PF00092
(VWA) 		3 ASP B 340
ARG B 477
THR B 410
 MG  B 602 ( 4.5A)
None
MG  B 602 ( 4.8A)
 0.87A 4i13A-1qc5B:
undetectable		 4i13A-1qc5B:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh4 CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ASP A  78
ARG A 209
THR A  47
 None
 0.83A 4i13A-1qh4A:
undetectable		 4i13A-1qh4A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu2 ISOLEUCYL-TRNA
SYNTHETASE

(Staphylococcus
aureus) 		PF00133
(tRNA-synt_1)
PF06827
(zf-FPG_IleRS)
PF08264
(Anticodon_1) 		3 ASP A  95
ARG A 455
THR A 154
 MRC  A1993 ( 4.7A)
None
None
 0.85A 4i13A-1qu2A:
undetectable		 4i13A-1qu2A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r2k MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B

(Escherichia
coli) 		no annotation 3 ASP B  26
ARG B 143
THR B  16
 None
 0.65A 4i13A-1r2kB:
undetectable		 4i13A-1r2kB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rqg METHIONYL-TRNA
SYNTHETASE

(Pyrococcus
abyssi) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		3 ASP A  50
ARG A 231
THR A  95
 None
 0.79A 4i13A-1rqgA:
undetectable		 4i13A-1rqgA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6r CREATINE KINASE, M
CHAIN

(Oryctolagus
cuniculus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ASP A  77
ARG A 208
THR A  46
 None
 0.84A 4i13A-1u6rA:
undetectable		 4i13A-1u6rA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vj0 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ASP A 148
ARG A 125
THR A 317
 None
 0.85A 4i13A-1vj0A:
2.6		 4i13A-1vj0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8o BACTERIAL SIALIDASE

(Micromonospora
viridifaciens) 		PF00754
(F5_F8_type_C)
PF10633
(NPCBM_assoc)
PF13088
(BNR_2) 		3 ASP A 259
ARG A  68
THR A 226
 GOL  A1651 (-2.8A)
CIT  A1649 ( 2.6A)
None
 0.87A 4i13A-1w8oA:
undetectable		 4i13A-1w8oA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdu TRAS1 ORF2P

(Bombyx mori) 		PF14529
(Exo_endo_phos_2) 		3 ASP A 211
ARG A 173
THR A 196
 None
 0.87A 4i13A-1wduA:
undetectable		 4i13A-1wduA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B

(Bacillus cereus) 		PF00994
(MoCF_biosynth) 		3 ASP A  30
ARG A 148
THR A  20
 None
 0.65A 4i13A-1y5eA:
undetectable		 4i13A-1y5eA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3q THAUMATIN-LIKE
PROTEIN

(Musa acuminata) 		PF00314
(Thaumatin) 		3 ASP A 180
ARG A 169
THR A 184
 None
EDO  A 901 (-4.3A)
None
 0.83A 4i13A-1z3qA:
undetectable		 4i13A-1z3qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zca G ALPHA I/12

(Mus musculus) 		PF00503
(G-alpha) 		3 ASP A 297
ARG A 168
THR A 350
 GDP  A 382 (-3.1A)
None
GDP  A 382 (-3.7A)
 0.89A 4i13A-1zcaA:
undetectable		 4i13A-1zcaA:
18.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zdr DIHYDROFOLATE
REDUCTASE

(Geobacillus
stearothermophilus) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  57
THR A 115
 None
SO4  A3484 (-3.3A)
None
 0.31A 4i13A-1zdrA:
23.6		 4i13A-1zdrA:
40.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azq CATECHOL
1,2-DIOXYGENASE

(Pseudomonas
putida) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		3 ASP A 127
ARG A 176
THR A 158
 None
 0.87A 4i13A-2azqA:
undetectable		 4i13A-2azqA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2blb DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
vivax) 		PF00186
(DHFR_1) 		3 ASP A  53
ARG A 131
THR A 194
 CP7  A1240 (-3.1A)
MES  A1241 (-2.7A)
CP7  A1240 (-4.1A)
 0.30A 4i13A-2blbA:
19.0		 4i13A-2blbA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8t ARGONAUTE PROTEIN

(Aquifex
aeolicus) 		PF02171
(Piwi) 		3 ASP A 577
ARG A 644
THR A 544
 None
 0.83A 4i13A-2f8tA:
undetectable		 4i13A-2f8tA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgq OUTER MEMBRANE PORIN
PROTEIN 32

(Delftia
acidovorans) 		PF13609
(Porin_4) 		3 ASP X 129
ARG X  92
THR X 194
 None
 0.88A 4i13A-2fgqX:
undetectable		 4i13A-2fgqX:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2q BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
cruzi) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ASP A  48
ARG A  94
THR A 178
 None
 0.18A 4i13A-2h2qA:
18.4		 4i13A-2h2qA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi0 PUTATIVE
PHOSPHOGLYCOLATE
PHOSPHATASE

(Lactobacillus
delbrueckii) 		PF13419
(HAD_2) 		3 ASP A  11
ARG A  57
THR A  17
 None
 0.84A 4i13A-2hi0A:
undetectable		 4i13A-2hi0A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz7 GLUTAMINYL-TRNA
SYNTHETASE

(Deinococcus
radiodurans) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		3 ASP A 375
ARG A 428
THR A 343
 None
 0.83A 4i13A-2hz7A:
undetectable		 4i13A-2hz7A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2is8 MOLYBDOPTERIN
BIOSYNTHESIS ENZYME,
MOAB

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth) 		3 ASP A  20
ARG A 136
THR A   8
 FMT  A1003 (-3.7A)
None
FMT  A1003 (-4.1A)
 0.71A 4i13A-2is8A:
undetectable		 4i13A-2is8A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv2 FORMATE
DEHYDROGENASE H

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 ASP X 343
ARG X 138
THR X 456
 None
 0.86A 4i13A-2iv2X:
undetectable		 4i13A-2iv2X:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgd 2-OXOGLUTARATE
DEHYDROGENASE E1
COMPONENT

(Escherichia
coli) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		3 ASP A 451
ARG A 261
THR A 409
 None
 0.75A 4i13A-2jgdA:
undetectable		 4i13A-2jgdA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oip CHAIN A, CRYSTAL
STRUCTURE OF DHFR

(Cryptosporidium
hominis) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ASP A  32
ARG A  70
THR A 134
 MTX  A 605 ( 3.0A)
MTX  A 605 ( 3.1A)
MTX  A 605 ( 4.2A)
 0.22A 4i13A-2oipA:
19.7		 4i13A-2oipA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		3 ASP A 660
ARG A 823
THR A 566
 None
 0.51A 4i13A-2vmfA:
undetectable		 4i13A-2vmfA:
11.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w3w DIHYDROFOLATE
REDUCTASE

(Mycobacterium
avium) 		PF00186
(DHFR_1) 		3 ASP A  31
ARG A  64
THR A 121
 VG9  A1168 (-3.0A)
VG9  A1168 ( 3.7A)
VG9  A1168 ( 4.7A)
 0.65A 4i13A-2w3wA:
23.1		 4i13A-2w3wA:
34.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w9s DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003

(Staphylococcus
aureus) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  57
THR A 111
 TOP  A1160 (-2.8A)
None
TOP  A1160 ( 4.5A)
 0.51A 4i13A-2w9sA:
23.7		 4i13A-2w9sA:
38.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yd0 ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ASP A 195
ARG A 430
THR A 244
 None
 0.74A 4i13A-2yd0A:
undetectable		 4i13A-2yd0A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		3 ASP A 218
ARG A 160
THR A 269
 None
ZN  A 647 ( 4.3A)
None
 0.73A 4i13A-2zwsA:
undetectable		 4i13A-2zwsA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3i PENICILLIN-BINDING
PROTEIN 4

(Haemophilus
influenzae) 		PF02113
(Peptidase_S13) 		3 ASP A 257
ARG A 154
THR A 146
 None
 0.90A 4i13A-3a3iA:
undetectable		 4i13A-3a3iA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT
C,LINKER,GLUTAMATE--
TRNA LIGASE 2

(Thermotoga
maritima;
Thermotoga
maritima;
synthetic
construct) 		PF01425
(Amidase)
PF00749
(tRNA-synt_1c)
PF02686
(Glu-tRNAGln) 		3 ASP A 221
ARG C  69
THR A  93
 None
 0.89A 4i13A-3al0A:
undetectable		 4i13A-3al0A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ch0 GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Cytophaga
hutchinsonii) 		PF03009
(GDPD) 		3 ASP A 219
ARG A 102
THR A 221
 EDO  A 275 ( 2.7A)
GOL  A 289 (-2.7A)
EDO  A 274 (-3.0A)
 0.87A 4i13A-3ch0A:
undetectable		 4i13A-3ch0A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctp PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Alkaliphilus
metalliredigens) 		PF13377
(Peripla_BP_3) 		3 ASP A 240
ARG A 124
THR A 281
 None
XLF  A 401 (-4.0A)
None
 0.80A 4i13A-3ctpA:
undetectable		 4i13A-3ctpA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfr DIHYDROFOLATE
REDUCTASE

(Lactobacillus
casei) 		PF00186
(DHFR_1) 		3 ASP A  26
ARG A  57
THR A 116
 MTX  A 164 ( 2.9A)
MTX  A 164 ( 2.9A)
MTX  A 164 ( 4.3A)
 0.32A 4i13A-3dfrA:
22.6		 4i13A-3dfrA:
29.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dg8 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00186
(DHFR_1) 		3 ASP A  54
ARG A 122
THR A 185
 RJ6  A 609 (-3.0A)
None
RJ6  A 609 ( 4.5A)
 0.24A 4i13A-3dg8A:
19.2		 4i13A-3dg8A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3m TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Ruegeria
pomeroyi) 		PF13377
(Peripla_BP_3) 		3 ASP A 257
ARG A 200
THR A 298
 None
 0.89A 4i13A-3e3mA:
2.4		 4i13A-3e3mA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exs RMPD
(HEXULOSE-6-PHOSPHAT
E SYNTHASE)

(Streptococcus
mutans) 		PF00215
(OMPdecase) 		3 ASP A  64
ARG A 144
THR A  87
 5RP  A 501 ( 4.8A)
None
None
 0.89A 4i13A-3exsA:
undetectable		 4i13A-3exsA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3git CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		3 ASP A 497
ARG A 685
THR A 521
 None
 0.77A 4i13A-3gitA:
undetectable		 4i13A-3gitA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gka N-ETHYLMALEIMIDE
REDUCTASE

(Burkholderia
pseudomallei) 		PF00724
(Oxidored_FMN) 		3 ASP A 245
ARG A 112
THR A 251
 None
 0.82A 4i13A-3gkaA:
undetectable		 4i13A-3gkaA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		3 ASP M 497
ARG M 685
THR M 521
 None
 0.89A 4i13A-3i04M:
undetectable		 4i13A-3i04M:
12.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i8a DIHYDROFOLATE
REDUCTASE

(Staphylococcus
aureus) 		PF00186
(DHFR_1) 		3 ASP X  27
ARG X  57
THR X 111
 N22  X 219 (-2.8A)
None
N22  X 219 (-4.4A)
 0.45A 4i13A-3i8aX:
23.9		 4i13A-3i8aX:
37.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju5 ARGININE KINASE

(Apostichopus
japonicus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ASP A  69
ARG A 199
THR A  42
 None
 0.88A 4i13A-3ju5A:
undetectable		 4i13A-3ju5A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kjr DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE

(Babesia bovis) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ASP A  37
ARG A  83
THR A 144
 None
 0.19A 4i13A-3kjrA:
19.8		 4i13A-3kjrA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjd OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Francisella
tularensis) 		PF00156
(Pribosyltran) 		3 ASP A 150
ARG A 203
THR A 163
 None
 0.67A 4i13A-3mjdA:
undetectable		 4i13A-3mjdA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olo TWO-COMPONENT SENSOR
HISTIDINE KINASE

(Nostoc sp. PCC
7120) 		PF00989
(PAS) 		3 ASP A  59
ARG A  71
THR A  80
 None
 0.77A 4i13A-3oloA:
undetectable		 4i13A-3oloA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oyz MALATE SYNTHASE

(Haloferax
volcanii) 		PF03328
(HpcH_HpaI) 		3 ASP A 188
ARG A  89
THR A 216
 None
 0.68A 4i13A-3oyzA:
undetectable		 4i13A-3oyzA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbd 3-DEHYDROQUINATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01761
(DHQ_synthase) 		3 ASP A 168
ARG A  58
THR A 171
 None
None
NAD  A 400 (-4.9A)
 0.82A 4i13A-3qbdA:
undetectable		 4i13A-3qbdA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg9 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
brucei) 		PF00186
(DHFR_1) 		3 ASP A  54
ARG A 100
THR A 184
 WRA  A 602 (-2.9A)
None
WRA  A 602 (-4.2A)
 0.28A 4i13A-3rg9A:
18.3		 4i13A-3rg9A:
27.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpd METHIONINE SYNTHASE
(B12-INDEPENDENT)

(Shewanella sp.
W3-18-1) 		PF01717
(Meth_synt_2) 		3 ASP A 125
ARG A 117
THR A  75
 None
 0.38A 4i13A-3rpdA:
undetectable		 4i13A-3rpdA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1

(Bos taurus) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase) 		3 ASP A 600
ARG A 677
THR A 357
 None
ACP  A1001 (-3.3A)
None
 0.64A 4i13A-3tlmA:
undetectable		 4i13A-3tlmA:
9.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tq9 DIHYDROFOLATE
REDUCTASE

(Coxiella
burnetii) 		PF00186
(DHFR_1) 		3 ASP A  28
ARG A  58
THR A 115
 MTX  A2001 (-2.7A)
MTX  A2001 (-2.8A)
MTX  A2001 (-4.3A)
 0.25A 4i13A-3tq9A:
23.7		 4i13A-3tq9A:
43.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um6 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ASP A  54
ARG A 122
THR A 185
 1CY  A 609 (-2.9A)
None
1CY  A 609 (-4.3A)
 0.25A 4i13A-3um6A:
19.2		 4i13A-3um6A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vco DIHYDROFOLATE
REDUCTASE

(Schistosoma
mansoni) 		PF00186
(DHFR_1) 		3 ASP A  28
ARG A  67
THR A 133
 None
 0.17A 4i13A-3vcoA:
18.8		 4i13A-3vcoA:
29.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w53 BETA-GLUCOSIDASE

(Micrococcus
antarcticus) 		PF00232
(Glyco_hydro_1) 		3 ASP A 303
ARG A 344
THR A 227
 None
 0.83A 4i13A-3w53A:
undetectable		 4i13A-3w53A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh4 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Streptococcus
pneumoniae) 		PF00275
(EPSP_synthase) 		3 ASP A 326
ARG A  92
THR A 297
 None
FLC  A1419 ( 4.0A)
None
 0.74A 4i13A-3zh4A:
undetectable		 4i13A-3zh4A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5q CHI1

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		3 ASP A 421
ARG A 101
THR A  48
 None
 0.90A 4i13A-4a5qA:
undetectable		 4i13A-4a5qA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab4 XENOBIOTIC REDUCTASE
B

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		3 ASP A 237
ARG A 104
THR A 243
 None
 0.89A 4i13A-4ab4A:
undetectable		 4i13A-4ab4A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bin N-ACETYLMURAMOYL-L-A
LANINE AMIDASE AMIC

(Escherichia
coli) 		PF01520
(Amidase_3)
PF11741
(AMIN) 		3 ASP A  95
ARG A 102
THR A  48
 None
 0.71A 4i13A-4binA:
2.1		 4i13A-4binA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckb MRNA-CAPPING ENZYME
CATALYTIC SUBUNIT

(Vaccinia virus) 		PF03291
(Pox_MCEL)
PF10640
(Pox_ATPase-GT) 		3 ASP A 545
ARG A 748
THR A 653
 None
 0.86A 4i13A-4ckbA:
2.8		 4i13A-4ckbA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dbg RANBP-TYPE AND
C3HC4-TYPE ZINC
FINGER-CONTAINING
PROTEIN 1
RING FINGER PROTEIN
31

(Homo sapiens;
Homo sapiens) 		no annotation
PF16678
(HOIP-UBA) 		3 ASP A  91
ARG A  76
THR B 610
 None
 0.89A 4i13A-4dbgA:
undetectable		 4i13A-4dbgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl9 TYROSINE-PROTEIN
KINASE

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		3 ASP A 873
ARG A 847
THR A 875
 None
 0.77A 4i13A-4gl9A:
undetectable		 4i13A-4gl9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH

(Vibrio
parahaemolyticus) 		PF02386
(TrkH) 		3 ASP A 209
ARG A  32
THR A 225
 None
 0.70A 4i13A-4j9uA:
undetectable		 4i13A-4j9uA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbm DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycobacterium
tuberculosis) 		PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1) 		3 ASP A 259
ARG A 224
THR A 229
 None
 0.80A 4i13A-4kbmA:
undetectable		 4i13A-4kbmA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lrs ACETALDEHYDE
DEHYDROGENASE

(Thermomonospora
curvata) 		PF01118
(Semialdhyde_dh)
PF09290
(AcetDehyd-dimer) 		3 ASP B  37
ARG B 284
THR B 301
 None
 0.89A 4i13A-4lrsB:
2.3		 4i13A-4lrsB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu6 FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE REBH

(Lechevalieria
aerocolonigenes) 		PF04820
(Trp_halogenase) 		3 ASP A 195
ARG A 231
THR A 215
 None
 0.83A 4i13A-4lu6A:
undetectable		 4i13A-4lu6A:
14.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m2x DIHYDROFOLATE
REDUCTASE

(Mycobacterium
tuberculosis) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  60
THR A 113
 TMQ  A 202 ( 2.7A)
None
TMQ  A 202 (-4.2A)
 0.39A 4i13A-4m2xA:
21.5		 4i13A-4m2xA:
35.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m7v DIHYDROFOLATE
REDUCTASE

(Enterococcus
faecalis) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  58
THR A 116
 RAR  A 200 (-2.6A)
RAR  A 200 ( 3.2A)
RAR  A 200 (-4.4A)
 0.52A 4i13A-4m7vA:
23.0		 4i13A-4m7vA:
37.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6m AF2299, A
CDP-ALCOHOL
PHOSPHOTRANSFERASE

(Archaeoglobus
fulgidus) 		PF01066
(CDP-OH_P_transf) 		3 ASP A 235
ARG A 304
THR A 178
 CA  A 401 (-2.2A)
SO4  A 411 (-2.6A)
None
 0.76A 4i13A-4o6mA:
undetectable		 4i13A-4o6mA:
18.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p68 DIHYDROFOLATE
REDUCTASE

(Escherichia
coli) 		PF00186
(DHFR_1) 		3 ASP A  27
ARG A  57
THR A 113
 MTX  A 201 (-3.0A)
MTX  A 201 (-3.0A)
MTX  A 201 ( 4.5A)
 0.25A 4i13A-4p68A:
28.3		 4i13A-4p68A:
98.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uy6 HISTIDINE-SPECIFIC
METHYLTRANSFERASE
EGTD

(Mycolicibacterium
smegmatis) 		PF10017
(Methyltransf_33) 		3 ASP A  48
ARG A  60
THR A  89
 None
 0.66A 4i13A-4uy6A:
2.9		 4i13A-4uy6A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgk NEUTRAL CERAMIDASE

(Homo sapiens) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		3 ASP A 317
ARG A 257
THR A 397
 None
ZN  A 801 ( 4.5A)
None
 0.71A 4i13A-4wgkA:
undetectable		 4i13A-4wgkA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bs5 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Acinetobacter
baumannii) 		PF00275
(EPSP_synthase) 		3 ASP A 361
ARG A 710
THR A 408
 None
 0.88A 4i13A-5bs5A:
undetectable		 4i13A-5bs5A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1k GEM-ASSOCIATED
PROTEIN 5

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		3 ASP A 696
ARG A   6
THR A 712
 None
 0.89A 4i13A-5h1kA:
undetectable		 4i13A-5h1kA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB

(Mus musculus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ASP A 870
ARG A 482
THR A 873
 None
 0.85A 4i13A-5hjrA:
undetectable		 4i13A-5hjrA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa) 		PF04453
(OstA_C) 		3 ASP A 596
ARG A  86
THR A 199
 None
 0.86A 4i13A-5ivaA:
undetectable		 4i13A-5ivaA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jo7 VETISPIRADIENE
SYNTHASE 1

(Hyoscyamus
muticus) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ASP A 451
ARG A 273
THR A 455
 None
 0.80A 4i13A-5jo7A:
undetectable		 4i13A-5jo7A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kiv PROTEIN-ADP-RIBOSE
HYDROLASE

(Staphylococcus
aureus) 		PF01661
(Macro) 		3 ASP A  93
ARG A  42
THR A  96
 None
 0.85A 4i13A-5kivA:
undetectable		 4i13A-5kivA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ASP A  69
ARG A  33
THR A  67
 NA  A 505 ( 3.0A)
None
NA  A 505 (-2.9A)
 0.88A 4i13A-5mb4A:
undetectable		 4i13A-5mb4A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o25 TMPDE

(Thermotoga
maritima) 		no annotation 3 ASP A  80
ARG A 267
THR A 124
 MN  A 401 ( 2.6A)
PG4  A 403 ( 3.6A)
None
 0.78A 4i13A-5o25A:
undetectable		 4i13A-5o25A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t0l BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Toxoplasma
gondii) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ASP A  31
ARG A  97
THR A 172
 73X  A 704 (-2.8A)
None
73X  A 704 (-4.2A)
 0.20A 4i13A-5t0lA:
19.9		 4i13A-5t0lA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usf TYROSYL-TRNA
SYNTHETASE, PUTATIVE

(Leishmania
donovani) 		PF00579
(tRNA-synt_1b) 		3 ASP A 263
ARG A 272
THR A 147
 None
 0.72A 4i13A-5usfA:
undetectable		 4i13A-5usfA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5via PSEUDOPEROXIDASE

(Leishmania
major) 		PF00141
(peroxidase) 		3 ASP A 104
ARG A 252
THR A 265
 None
 0.77A 4i13A-5viaA:
undetectable		 4i13A-5viaA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9w DNA MISMATCH REPAIR
PROTEIN MUTS

(Neisseria
gonorrhoeae) 		no annotation 3 ASP A 644
ARG A 270
THR A 678
 None
 0.87A 4i13A-5x9wA:
undetectable		 4i13A-5x9wA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3

(Armillaria
tabescens) 		no annotation 3 ASP A 489
ARG A 394
THR A 312
 None
 0.61A 4i13A-5yfbA:
undetectable		 4i13A-5yfbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z4i UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 20

(Homo sapiens) 		no annotation 3 ASP A  59
ARG A  80
THR A  62
 None
 0.84A 4i13A-5z4iA:
undetectable		 4i13A-5z4iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zm4 DIOXYGENASE ANDA

(Aspergillus
stellatus) 		no annotation 3 ASP A 281
ARG A 247
THR A 265
 None
 0.85A 4i13A-5zm4A:
undetectable		 4i13A-5zm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bgd GLUCOSE/GALACTOSE-BI
NDING LIPOPROTEIN

(Treponema
pallidum) 		no annotation 3 ASP A 173
ARG A 285
THR A 212
 None
 0.84A 4i13A-6bgdA:
undetectable		 4i13A-6bgdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6chs PUTATIVE CELL
DIVISION CONTROL
PROTEIN

(Chaetomium
thermophilum) 		no annotation 3 ASP H 320
ARG H 365
THR H 268
 MG  H 903 (-3.1A)
None
MG  H 903 ( 3.5A)
 0.89A 4i13A-6chsH:
undetectable		 4i13A-6chsH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxd PEPTIDASE B

(Yersinia pestis) 		no annotation 3 ASP A 397
ARG A 403
THR A 307
 None
None
SO4  A 503 (-4.6A)
 0.74A 4i13A-6cxdA:
undetectable		 4i13A-6cxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxm DIHYDROFOLATE
REDUCTASE

(Mycolicibacterium
smegmatis) 		no annotation 3 ASP A  28
ARG A  61
THR A 111
 MMV  A 202 (-2.9A)
MMV  A 202 (-2.8A)
MMV  A 202 (-4.4A)
 0.34A 4i13A-6cxmA:
20.1		 4i13A-6cxmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e4e -

(-) 		no annotation 3 ASP A  27
ARG A  57
THR A 111
 MMV  A 202 (-2.9A)
None
MMV  A 202 (-4.3A)
 0.40A 4i13A-6e4eA:
23.8		 4i13A-6e4eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6enz ACIDIC AMINO ACID
DECARBOXYLASE GADL1

(Mus musculus) 		no annotation 3 ASP A 107
ARG A 392
THR A 377
 None
 0.81A 4i13A-6enzA:
undetectable		 4i13A-6enzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A1252
ARG A 506
THR A  34
 None
 0.86A 4i13A-6eojA:
undetectable		 4i13A-6eojA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f91 PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		no annotation 3 ASP A  76
ARG A  43
THR A  64
 None
 0.87A 4i13A-6f91A:
undetectable		 4i13A-6f91A:
undetectable