SIMILAR PATTERNS OF AMINO ACIDS FOR 4HTF_A_ACTA303_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dwa MYROSINASE MA1

(Sinapis alba) 		PF00232
(Glyco_hydro_1) 		3 TYR M 224
HIS M 347
ARG M 306
 None
 0.98A 4htfA-1dwaM:
undetectable		 4htfA-1dwaM:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus) 		PF01896
(DNA_primase_S) 		3 TYR A  72
HIS A 298
ARG A 292
 None
SO4  A 352 (-4.0A)
SO4  A 352 (-3.9A)
 1.11A 4htfA-1g71A:
undetectable		 4htfA-1g71A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k12 LECTIN

(Anguilla
anguilla) 		PF00754
(F5_F8_type_C) 		3 TYR A  46
HIS A  52
ARG A  79
 None
FUC  A 159 (-3.8A)
FUC  A 159 (-2.7A)
 1.10A 4htfA-1k12A:
undetectable		 4htfA-1k12A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		3 TYR A 359
HIS A 269
ARG A 303
 None
 1.10A 4htfA-1k9xA:
undetectable		 4htfA-1k9xA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE
METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus;
Methylococcus
capsulatus) 		PF02332
(Phenol_Hydrox)
PF02332
(Phenol_Hydrox) 		3 TYR B  37
HIS D 486
ARG D 173
 None
 0.85A 4htfA-1mtyB:
undetectable		 4htfA-1mtyB:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 TYR A 784
HIS A 335
ARG A 329
 None
 0.81A 4htfA-1nl3A:
3.2		 4htfA-1nl3A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nyl GLUTAMINYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		3 TYR A 523
HIS A 368
ARG A 341
 None
 0.83A 4htfA-1nylA:
1.8		 4htfA-1nylA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgu PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)

(Klebsiella
pneumoniae) 		PF00148
(Oxidored_nitro) 		3 TYR A 274
HIS A 381
ARG A 275
 None
 0.78A 4htfA-1qguA:
2.5		 4htfA-1qguA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qp8 FORMATE
DEHYDROGENASE

(Pyrobaculum
aerophilum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 TYR A 265
HIS A  63
ARG A  39
 None
 1.06A 4htfA-1qp8A:
7.2		 4htfA-1qp8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szq 2-METHYLCITRATE
DEHYDRATASE

(Escherichia
coli) 		PF03972
(MmgE_PrpD) 		3 TYR A 211
HIS A 171
ARG A 212
 None
 0.96A 4htfA-1szqA:
undetectable		 4htfA-1szqA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6k PHENAZINE
BIOSYNTHESIS PROTEIN
PHZF

(Pseudomonas
fluorescens) 		PF02567
(PhzC-PhzF) 		3 TYR A 149
HIS A 225
ARG A 224
 None
 1.15A 4htfA-1t6kA:
undetectable		 4htfA-1t6kA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT

(Pyrococcus
horikoshii) 		PF01896
(DNA_primase_S) 		3 TYR A  72
HIS A 298
ARG A 292
 None
PO4  A 701 (-3.8A)
PO4  A 701 (-4.2A)
 1.02A 4htfA-1v33A:
undetectable		 4htfA-1v33A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6j LANOSTEROL SYNTHASE

(Homo sapiens) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		3 TYR A 244
HIS A 307
ARG A 312
 None
 1.00A 4htfA-1w6jA:
undetectable		 4htfA-1w6jA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0u ARSENICAL RESISTANCE
OPERON REPRESSOR,
PUTATIVE

(Archaeoglobus
fulgidus) 		PF12840
(HTH_20) 		3 TYR A  24
HIS A  61
ARG A  31
 None
 0.68A 4htfA-1y0uA:
undetectable		 4htfA-1y0uA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		3 TYR A 200
HIS A 141
ARG A 137
 None
 1.15A 4htfA-1y9uA:
undetectable		 4htfA-1y9uA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4

(Viscum album) 		PF00161
(RIP) 		3 TYR A 110
HIS A 119
ARG A 120
 None
 1.09A 4htfA-1yf8A:
undetectable		 4htfA-1yf8A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5h L-LYSINE
2,3-AMINOMUTASE

(Clostridium
subterminale) 		PF04055
(Radical_SAM)
PF12544
(LAM_C) 		3 TYR A  63
HIS A 230
ARG A 202
 None
SAM  A 417 ( 3.6A)
None
 1.00A 4htfA-2a5hA:
undetectable		 4htfA-2a5hA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azk GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Sulfolobus
solfataricus) 		PF00348
(polyprenyl_synt) 		3 TYR A 196
HIS A  74
ARG A  45
 None
 1.04A 4htfA-2azkA:
undetectable		 4htfA-2azkA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		3 TYR A 378
HIS A 490
ARG A 488
 None
 1.07A 4htfA-2b0tA:
undetectable		 4htfA-2b0tA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1m L-GLUTAMATE OXIDASE
L-GLUTAMATE OXIDASE

(Streptomyces
sp. X-119-6;
Streptomyces
sp. X-119-6) 		PF01593
(Amino_oxidase)
PF01593
(Amino_oxidase) 		3 TYR C 530
HIS A 193
ARG A 191
 None
 1.01A 4htfA-2e1mC:
undetectable		 4htfA-2e1mC:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1s VIRAL CASP8 AND
FADD-LIKE APOPTOSIS
REGULATOR

(Molluscum
contagiosum
virus) 		PF01335
(DED) 		3 TYR A  96
HIS A  33
ARG A  97
 None
 1.05A 4htfA-2f1sA:
undetectable		 4htfA-2f1sA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibb CG9211-PA

(Drosophila
melanogaster) 		PF00041
(fn3) 		3 TYR A 613
HIS A 635
ARG A 637
 None
 1.03A 4htfA-2ibbA:
undetectable		 4htfA-2ibbA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nym SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
CATALYTIC SUBUNIT
ALPHA ISOFORM

(Homo sapiens) 		PF00149
(Metallophos) 		3 TYR C 267
HIS C  63
ARG C 294
 None
 1.14A 4htfA-2nymC:
undetectable		 4htfA-2nymC:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlz TRANSCRIPTION FACTOR
PF0095

(Pyrococcus
furiosus) 		PF12840
(HTH_20) 		3 TYR A   7
HIS A  45
ARG A  14
 None
 0.75A 4htfA-2qlzA:
undetectable		 4htfA-2qlzA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vy2 PROTEIN LEAFY

(Arabidopsis
thaliana) 		PF17538
(C_LFY_FLO) 		3 TYR A 349
HIS A 312
ARG A 345
 None
 0.97A 4htfA-2vy2A:
undetectable		 4htfA-2vy2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbp L-ARGININE
BETA-HYDROXYLASE

(Streptomyces
vinaceus) 		PF02668
(TauD) 		3 TYR A 180
HIS A 264
ARG A 312
 None
 1.13A 4htfA-2wbpA:
undetectable		 4htfA-2wbpA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wfx HEDGEHOG-INTERACTING
PROTEIN

(Homo sapiens) 		PF07995
(GSDH) 		3 TYR B 293
HIS B 332
ARG B 241
 None
 0.99A 4htfA-2wfxB:
undetectable		 4htfA-2wfxB:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xqy A13-D6.3 MONOCLONAL
ANTIBODY

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR G  99
HIS G  58
ARG G  50
 None
 0.74A 4htfA-2xqyG:
undetectable		 4htfA-2xqyG:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding)
PF15447
(NTS) 		3 TYR A 305
HIS A 288
ARG A 280
 None
 0.86A 4htfA-2xu0A:
undetectable		 4htfA-2xu0A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yk0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding)
PF15447
(NTS) 		3 TYR A 305
HIS A 288
ARG A 280
 None
 0.81A 4htfA-2yk0A:
undetectable		 4htfA-2yk0A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4g HISTIDINOL
PHOSPHATASE

(Thermus
thermophilus) 		PF02811
(PHP)
PF13263
(PHP_C) 		3 TYR A  45
HIS A  38
ARG A  50
 None
ZN  A 501 (-3.2A)
None
 1.10A 4htfA-2z4gA:
undetectable		 4htfA-2z4gA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zux YESW PROTEIN

(Bacillus
subtilis) 		no annotation 3 TYR A 326
HIS A 214
ARG A 304
 None
 1.09A 4htfA-2zuxA:
undetectable		 4htfA-2zuxA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		3 TYR A 460
HIS A 204
ARG A 160
 GOL  A 656 (-4.5A)
ZN  A 647 (-3.3A)
ZN  A 647 ( 4.3A)
 0.93A 4htfA-2zwsA:
undetectable		 4htfA-2zwsA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cr8 SULFATE
ADENYLYLTRANSFERASE,
ADENYLYLSULFATE
KINASE

(Thiobacillus
denitrificans) 		PF01583
(APS_kinase)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 TYR A 210
HIS A 141
ARG A 148
 None
 1.17A 4htfA-3cr8A:
undetectable		 4htfA-3cr8A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dew TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Geobacter
sulfurreducens) 		PF00440
(TetR_N) 		3 TYR A  84
HIS A  92
ARG A  91
 ACY  A 209 (-4.6A)
None
ACY  A 209 (-3.7A)
 1.17A 4htfA-3dewA:
undetectable		 4htfA-3dewA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmk DOWN SYNDROME CELL
ADHESION MOLECULE
(DSCAM) ISOFORM
1.30.30, N-TERMINAL
EIGHT IG DOMAINS

(Drosophila
melanogaster) 		PF07679
(I-set)
PF13927
(Ig_3) 		3 TYR A 441
HIS A 463
ARG A 440
 None
 1.13A 4htfA-3dmkA:
undetectable		 4htfA-3dmkA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd7 FUSION COMPLEX OF
CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR, RESIDUES
1193-1427 AND
MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK,
RESIDUES 219-371

(Escherichia
coli;
Homo sapiens) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 TYR A1433
HIS A1575
ARG A1573
 None
 1.17A 4htfA-3gd7A:
undetectable		 4htfA-3gd7A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ipi GERANYLTRANSTRANSFER
ASE

(Methanosarcina
mazei) 		PF00348
(polyprenyl_synt) 		3 TYR A 211
HIS A  83
ARG A  54
 None
MLA  A 305 ( 4.7A)
MLA  A 305 (-4.0A)
 1.02A 4htfA-3ipiA:
undetectable		 4htfA-3ipiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kwl UNCHARACTERIZED
PROTEIN

(Helicobacter
pylori) 		no annotation 3 TYR A 423
HIS A 490
ARG A 422
 None
 1.00A 4htfA-3kwlA:
undetectable		 4htfA-3kwlA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lad DIHYDROLIPOAMIDE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 TYR A 314
HIS A 343
ARG A 339
 None
 0.93A 4htfA-3ladA:
2.8		 4htfA-3ladA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lyd UNCHARACTERIZED
PROTEIN

(Jonesia
denitrificans) 		PF10738
(Lpp-LpqN) 		3 TYR A   6
HIS A 120
ARG A  56
 None
 1.01A 4htfA-3lydA:
undetectable		 4htfA-3lydA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3moi PROBABLE
DEHYDROGENASE

(Bordetella
bronchiseptica) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 TYR A  48
HIS A  24
ARG A  23
 None
 1.10A 4htfA-3moiA:
5.7		 4htfA-3moiA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nhi D7 PROTEIN

(Anopheles
stephensi) 		PF01395
(PBP_GOBP) 		3 TYR A 179
HIS A 157
ARG A 177
 SO4  A 299 (-4.9A)
None
None
 0.94A 4htfA-3nhiA:
undetectable		 4htfA-3nhiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opz HEAVY CHAIN OF THE
FAB FRAGMENT OF
IMMUNOGLOBULIN G

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H 108
HIS H 100
ARG H  98
 None
 0.94A 4htfA-3opzH:
undetectable		 4htfA-3opzH:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pko GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE

(Lactobacillus
brevis) 		PF00348
(polyprenyl_synt) 		3 TYR A 211
HIS A  80
ARG A  50
 CIT  A 326 (-4.6A)
CIT  A 326 (-3.9A)
CIT  A 326 (-2.6A)
 1.10A 4htfA-3pkoA:
undetectable		 4htfA-3pkoA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		3 TYR A 277
HIS A 203
ARG A 221
 None
 1.17A 4htfA-3pmkA:
undetectable		 4htfA-3pmkA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwe GEM-INTERACTING
PROTEIN

(Homo sapiens) 		no annotation 3 TYR A 150
HIS A 145
ARG A 344
 UNX  A  22 ( 4.6A)
None
UNX  A  19 ( 4.9A)
 0.77A 4htfA-3qweA:
undetectable		 4htfA-3qweA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3a V-TYPE ATP SYNTHASE
ALPHA CHAIN

(Thermus
thermophilus) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn) 		3 TYR A 184
HIS A 109
ARG A 113
 None
 1.03A 4htfA-3w3aA:
undetectable		 4htfA-3w3aA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avx HEPATOCYTE GROWTH
FACTOR-REGULATED
TYROSINE KINASE
SUBSTRATE

(Homo sapiens) 		PF00790
(VHS)
PF01363
(FYVE) 		3 TYR A 197
HIS A 180
ARG A 210
 None
ITP  A1227 (-3.7A)
ITP  A1227 (-4.1A)
 1.04A 4htfA-4avxA:
undetectable		 4htfA-4avxA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by6 GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF04054
(Not1) 		3 TYR A1994
HIS A1828
ARG A1993
 None
 0.91A 4htfA-4by6A:
undetectable		 4htfA-4by6A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0d CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF04054
(Not1) 		3 TYR A2276
HIS A2114
ARG A2275
 None
 0.82A 4htfA-4c0dA:
undetectable		 4htfA-4c0dA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cag POLYSACCHARIDE LYASE
FAMILY 11 PROTEIN

(Bacillus
licheniformis) 		PF01839
(FG-GAP) 		3 TYR A 296
HIS A 184
ARG A 274
 GOL  A 611 (-4.6A)
None
GOL  A 611 ( 4.2A)
 1.15A 4htfA-4cagA:
undetectable		 4htfA-4cagA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chb KELCH-LIKE PROTEIN 2

(Homo sapiens) 		PF01344
(Kelch_1) 		3 TYR A 583
HIS A 504
ARG A 534
 None
 0.84A 4htfA-4chbA:
undetectable		 4htfA-4chbA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw4 BETA-KETOACYL
SYNTHASE

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 TYR A 491
HIS A  23
ARG A  26
 None
 1.10A 4htfA-4cw4A:
undetectable		 4htfA-4cw4A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ds2 UBIQUITIN-CONJUGATIN
G ENZYME E2,
PUTATIVE

(Trypanosoma
cruzi) 		PF00179
(UQ_con) 		3 TYR A  77
HIS A 115
ARG A   8
 None
 1.03A 4htfA-4ds2A:
undetectable		 4htfA-4ds2A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Xanthomonas
campestris) 		PF00563
(EAL) 		3 TYR A  39
HIS A  90
ARG A  85
 None
 0.78A 4htfA-4f48A:
undetectable		 4htfA-4f48A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fo0 ACTIN-RELATED
PROTEIN 8

(Homo sapiens) 		PF00022
(Actin) 		3 TYR A 180
HIS A 162
ARG A  78
 None
 1.01A 4htfA-4fo0A:
undetectable		 4htfA-4fo0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fp4 POLYPRENYL
SYNTHETASE

(Pyrobaculum
calidifontis) 		PF00348
(polyprenyl_synt) 		3 TYR A 198
HIS A  79
ARG A  47
 None
UNL  A 303 ( 4.1A)
UNL  A 303 ( 2.8A)
 1.12A 4htfA-4fp4A:
undetectable		 4htfA-4fp4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0b HYDROXYCINNAMOYL-COA
SHIKIMATE/QUINATE
HYDROXYCINNAMOYLTRAN
SFERASE

(Coffea
canephora) 		PF02458
(Transferase) 		3 TYR A 130
HIS A 154
ARG A 152
 None
 1.01A 4htfA-4g0bA:
undetectable		 4htfA-4g0bA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gz7 DIHYDROPYRIMIDINASE

(Tetraodon
nigroviridis) 		PF01979
(Amidohydro_1) 		3 TYR A 160
HIS A 213
ARG A 217
 MHA  A 602 (-4.0A)
MHA  A 603 (-3.1A)
MHA  A 603 (-4.0A)
 0.98A 4htfA-4gz7A:
undetectable		 4htfA-4gz7A:
20.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4htf S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Escherichia
coli) 		PF13847
(Methyltransf_31) 		3 TYR B 150
HIS B 158
ARG B 246
 None
 0.14A 4htfA-4htfB:
37.9		 4htfA-4htfB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		3 TYR A 506
HIS A 306
ARG A 336
 None
 1.11A 4htfA-4jsoA:
undetectable		 4htfA-4jsoA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jza UNCHARACTERIZED
PROTEIN

(Legionella
longbeachae) 		no annotation 3 TYR A  41
HIS A 606
ARG A 603
 None
 0.42A 4htfA-4jzaA:
undetectable		 4htfA-4jzaA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lqx TENA/THI-4
DOMAIN-CONTAINING
PROTEIN

(Sulfolobus
solfataricus) 		PF03070
(TENA_THI-4)
PF16293
(zf-C2H2_9) 		3 TYR A 218
HIS A 104
ARG A 286
 UNL  A 402 ( 4.7A)
UNL  A 402 ( 4.5A)
UNL  A 402 ( 3.1A)
 1.04A 4htfA-4lqxA:
undetectable		 4htfA-4lqxA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE

(Janthinobacterium
sp. J3) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 TYR A 124
HIS A 381
ARG A  26
 None
 1.11A 4htfA-4nbgA:
undetectable		 4htfA-4nbgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		3 TYR A 366
HIS A 265
ARG A 147
 None
 0.98A 4htfA-4nleA:
undetectable		 4htfA-4nleA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5m ISOVALERYL-COA
DEHYDROGENASE

(Brucella suis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 TYR A 300
HIS A   0
ARG A  13
 None
 1.11A 4htfA-4o5mA:
undetectable		 4htfA-4o5mA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 TYR A 778
HIS A 830
ARG A 244
 None
 0.99A 4htfA-4q73A:
4.2		 4htfA-4q73A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlb PROBABLE GLYCOGEN
[STARCH] SYNTHASE

(Caenorhabditis
elegans) 		PF05693
(Glycogen_syn) 		3 TYR A  79
HIS A 196
ARG A 630
 None
 1.08A 4htfA-4qlbA:
2.5		 4htfA-4qlbA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgk NEUTRAL CERAMIDASE

(Homo sapiens) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		3 TYR A 591
HIS A 303
ARG A 257
 PO4  A 810 (-4.4A)
ZN  A 801 ( 3.2A)
ZN  A 801 ( 4.5A)
 1.01A 4htfA-4wgkA:
undetectable		 4htfA-4wgkA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzb NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		3 TYR A 276
HIS A 383
ARG A 277
 None
 0.76A 4htfA-4wzbA:
undetectable		 4htfA-4wzbA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		3 TYR A 528
HIS A 371
ARG A 343
 None
 1.01A 4htfA-5bnzA:
3.1		 4htfA-5bnzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq9 UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		PF12252
(SidE) 		3 TYR A 445
HIS A 366
ARG A 416
 None
 1.04A 4htfA-5bq9A:
undetectable		 4htfA-5bq9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu1 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 TYR A 445
HIS A 366
ARG A 416
 None
 0.99A 4htfA-5bu1A:
undetectable		 4htfA-5bu1A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu2 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 TYR A 445
HIS A 366
ARG A 416
 ADP  A 702 (-3.6A)
ADP  A 702 (-4.2A)
ADP  A 702 (-3.4A)
 0.98A 4htfA-5bu2A:
undetectable		 4htfA-5bu2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c8s GUANINE-N7
METHYLTRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06471
(NSP11) 		3 TYR B 446
HIS B 486
ARG B 476
 None
 0.98A 4htfA-5c8sB:
7.9		 4htfA-5c8sB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		3 TYR A 176
HIS A 111
ARG A  92
 None
A  B  50 ( 3.9A)
None
 1.13A 4htfA-5czzA:
undetectable		 4htfA-5czzA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1x D4-30 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B 102
HIS B  32
ARG B  94
 None
 0.95A 4htfA-5d1xB:
undetectable		 4htfA-5d1xB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ddv 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01128
(IspD) 		3 TYR A  68
HIS A  35
ARG A  38
 None
 1.03A 4htfA-5ddvA:
undetectable		 4htfA-5ddvA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dud YBGK
YBGJ

(Escherichia
coli;
Escherichia
coli) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		3 TYR B   7
HIS A 227
ARG A 257
 None
 0.94A 4htfA-5dudB:
undetectable		 4htfA-5dudB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3x THERMOSTABLE
CARBOXYPEPTIDASE 1

(Fervidobacterium
islandicum) 		PF02074
(Peptidase_M32) 		3 TYR A 343
HIS A 253
ARG A 287
 None
CO  A 501 (-3.3A)
None
 1.16A 4htfA-5e3xA:
undetectable		 4htfA-5e3xA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5et1 ESPIN
MYOSIN-IIIB

(Mus musculus;
Mus musculus) 		PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5)
no annotation 		3 TYR C1267
HIS A  42
ARG A  45
 None
 1.00A 4htfA-5et1C:
undetectable		 4htfA-5et1C:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evj ARSENITE
METHYLTRANSFERASE

(Chlamydomonas
reinhardtii) 		PF13847
(Methyltransf_31) 		3 TYR A 304
HIS A 196
ARG A 272
 None
 1.13A 4htfA-5evjA:
14.0		 4htfA-5evjA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjn L-AMINO ACID
DEAMINASE

(Cosenzaea
myxofaciens) 		PF01266
(DAO) 		3 TYR A 104
HIS A 296
ARG A 139
 None
 1.17A 4htfA-5fjnA:
undetectable		 4htfA-5fjnA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 TYR A 234
HIS A  12
ARG A 203
 None
 1.05A 4htfA-5fkuA:
undetectable		 4htfA-5fkuA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF04054
(Not1) 		3 TYR A2276
HIS A2114
ARG A2275
 None
 0.86A 4htfA-5fu7A:
undetectable		 4htfA-5fu7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5giv CARBOXYPEPTIDASE 1

(Deinococcus
radiodurans) 		PF02074
(Peptidase_M32) 		3 TYR A 357
HIS A 266
ARG A 300
 None
ZN  A 601 (-3.4A)
None
 1.14A 4htfA-5givA:
undetectable		 4htfA-5givA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koj NITROGENASE PROTEIN
ALPHA CHAIN

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro) 		3 TYR A 292
HIS A 399
ARG A 293
 None
 0.74A 4htfA-5kojA:
undetectable		 4htfA-5kojA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mux 2-METHYLCITRATE
DEHYDRATASE

(Bacillus
subtilis) 		no annotation 3 TYR A 203
HIS A 163
ARG A 204
 None
TLA  A 501 (-3.9A)
TLA  A 501 (-3.9A)
 1.01A 4htfA-5muxA:
undetectable		 4htfA-5muxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o77 OMPK35

(Klebsiella
pneumoniae) 		no annotation 3 TYR A 317
HIS A 238
ARG A 275
 None
 1.15A 4htfA-5o77A:
undetectable		 4htfA-5o77A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3b GLYCOSIDE HYDROLASE

(Bacteroides
plebeius) 		no annotation 3 TYR A 451
HIS A 140
ARG A 102
 None
 0.93A 4htfA-5t3bA:
undetectable		 4htfA-5t3bA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uam ULVAN LYASE-PL25

(Pseudoalteromonas
sp. PLSV) 		PF15892
(BNR_4) 		3 TYR A 188
HIS A 208
ARG A 204
 EDO  A 511 ( 3.0A)
ZN  A 502 ( 3.1A)
PO4  A 503 ( 3.0A)
 1.09A 4htfA-5uamA:
undetectable		 4htfA-5uamA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vae ACCESSORY SEC SYSTEM
PROTEIN ASP1

(Streptococcus
gordonii) 		no annotation 3 TYR A 462
HIS A 259
ARG A 284
 None
 1.06A 4htfA-5vaeA:
3.9		 4htfA-5vaeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xj1 UNCHARACTERIZED RNA
METHYLTRANSFERASE
SP_1029

(Streptococcus
pneumoniae) 		no annotation 3 TYR A  60
HIS A  85
ARG A  67
 None
 1.00A 4htfA-5xj1A:
15.1		 4htfA-5xj1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xst POLY [ADP-RIBOSE]
POLYMERASE 1

(Homo sapiens) 		no annotation 3 TYR A  28
HIS A 248
ARG A 204
 None
 1.10A 4htfA-5xstA:
undetectable		 4htfA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a91


(;
) 		no annotation
no annotation 		3 TYR B  16
HIS A1077
ARG B  55
 None
 1.05A 4htfA-6a91B:
undetectable		 4htfA-6a91B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cia ALDO/KETO REDUCTASE

(Klebsiella
pneumoniae) 		no annotation 3 TYR A 168
HIS A 234
ARG A 233
 None
 1.03A 4htfA-6ciaA:
undetectable		 4htfA-6ciaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6em0 2-HYDROXYBIPHENYL-3-
MONOOXYGENASE

(Pseudomonas
nitroreducens) 		no annotation 3 TYR A 463
HIS A 472
ARG A  53
 None
 0.97A 4htfA-6em0A:
undetectable		 4htfA-6em0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6flj CENTROSOMAL PROTEIN
OF 120 KDA

(Homo sapiens) 		no annotation 3 TYR A 119
HIS A  26
ARG A  23
 None
 1.18A 4htfA-6fljA:
undetectable		 4htfA-6fljA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g3u -

(-) 		no annotation 3 TYR A 382
HIS A 494
ARG A 492
 None
 1.13A 4htfA-6g3uA:
undetectable		 4htfA-6g3uA:
undetectable