SIMILAR PATTERNS OF AMINO ACIDS FOR 4HDL_A_DXCA75

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyy ALDEHYDE
DEHYDROGENASE

(Vibrio harveyi) 		PF00171
(Aldedh) 		4 ILE A 314
ILE A 385
PHE A 361
GLY A 339
 None
 0.86A 4hdlA-1eyyA:
0.0		 4hdlA-1eyyA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f89 32.5 KDA PROTEIN
YLR351C

(Saccharomyces
cerevisiae) 		PF00795
(CN_hydrolase) 		4 ILE A  11
ILE A 190
LYS A 184
GLY A 185
 None
 0.94A 4hdlA-1f89A:
0.0		 4hdlA-1f89A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		4 ILE A 223
ILE A 469
PHE A 448
GLY A 132
 None
 0.87A 4hdlA-1gqrA:
0.0		 4hdlA-1gqrA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE

(Escherichia
virus T4) 		PF09198
(T4-Gluco-transf) 		4 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.96A 4hdlA-1jiuA:
undetectable		 4hdlA-1jiuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus) 		PF01709
(Transcrip_reg) 		4 ILE A 209
LYS A 220
ILE A 219
GLY A 122
 None
 0.93A 4hdlA-1lfpA:
0.0		 4hdlA-1lfpA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A

(Haemophilus
influenzae) 		PF06026
(Rib_5-P_isom_A) 		5 ILE A 116
LYS A 112
ILE A  78
PHE A 113
GLY A 203
 None
 1.10A 4hdlA-1m0sA:
0.0		 4hdlA-1m0sA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1j FIBRINOGEN BETA
CHAIN

(Gallus gallus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 ILE B 232
LYS B 313
ILE B 257
GLY B 252
 None
 0.93A 4hdlA-1m1jB:
undetectable		 4hdlA-1m1jB:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7d LYSOSOMAL
ALPHA-MANNOSIDASE

(Bos taurus) 		PF01074
(Glyco_hydro_38) 		4 ILE A 117
ILE A 195
PHE A 217
GLY A 215
 None
 0.83A 4hdlA-1o7dA:
0.0		 4hdlA-1o7dA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofm CHONDROITINASE B

(Pedobacter
heparinus) 		PF14592
(Chondroitinas_B) 		4 ILE A 460
ILE A 348
PHE A 309
GLY A 294
 None
 0.97A 4hdlA-1ofmA:
undetectable		 4hdlA-1ofmA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pix GLUTACONYL-COA
DECARBOXYLASE A
SUBUNIT

(Acidaminococcus
fermentans) 		PF01039
(Carboxyl_trans) 		4 LYS A 385
ILE A 382
MET A 346
GLY A 390
 None
 0.94A 4hdlA-1pixA:
0.0		 4hdlA-1pixA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6m GALACTOSE-BINDING
LECTIN

(Arachis
hypogaea) 		PF00139
(Lectin_legB) 		4 ILE A 140
ILE A  89
PHE A 117
GLY A 115
 None
 0.87A 4hdlA-1v6mA:
0.0		 4hdlA-1v6mA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vkz PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Thermotoga
maritima) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 ILE A  18
ILE A  61
PHE A  82
GLY A 301
 None
 0.86A 4hdlA-1vkzA:
undetectable		 4hdlA-1vkzA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1w STRUCTURAL
MAINTENANCE OF
CHROMOSOME 1

(Saccharomyces
cerevisiae) 		PF02463
(SMC_N) 		4 ILE A1175
LYS A   2
ILE A1186
PHE A1154
 None
 0.94A 4hdlA-1w1wA:
undetectable		 4hdlA-1w1wA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zi0 DNA GYRASE SUBUNIT A

(Escherichia
coli) 		PF03989
(DNA_gyraseA_C) 		4 ILE A 619
ILE A 590
LYS A 671
GLY A 670
 None
 0.97A 4hdlA-1zi0A:
undetectable		 4hdlA-1zi0A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlt SERINE/THREONINE-PRO
TEIN KINASE CHK1

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A  58
LYS A 132
ILE A 146
GLY A  18
 None
None
None
HYM  A 400 ( 3.7A)
 0.81A 4hdlA-1zltA:
undetectable		 4hdlA-1zltA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bty ACETYLGLUTAMATE
KINASE

(Thermotoga
maritima) 		PF00696
(AA_kinase) 		4 ILE A 255
ILE A  26
MET A  33
GLY A  30
 None
None
None
NLG  A1284 (-2.7A)
 0.91A 4hdlA-2btyA:
undetectable		 4hdlA-2btyA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhk FORMYLMETHANOFURAN--
TETRAHYDROMETHANOPTE
RIN
FORMYLTRANSFERASE

(Methanopyrus
kandleri) 		PF01913
(FTR)
PF02741
(FTR_C) 		4 ILE A  25
ILE A  77
PHE A 158
GLY A 121
 None
 0.85A 4hdlA-2fhkA:
undetectable		 4hdlA-2fhkA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhk FORMYLMETHANOFURAN--
TETRAHYDROMETHANOPTE
RIN
FORMYLTRANSFERASE

(Methanopyrus
kandleri) 		PF01913
(FTR)
PF02741
(FTR_C) 		4 ILE A  77
ILE A 160
PHE A 158
GLY A 121
 None
 0.93A 4hdlA-2fhkA:
undetectable		 4hdlA-2fhkA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfg BH2851

(Bacillus
halodurans) 		PF01928
(CYTH) 		4 ILE A 128
ILE A 150
PHE A 152
GLY A 154
 None
None
EDO  A 504 ( 4.9A)
EDO  A 504 (-3.2A)
 0.95A 4hdlA-2gfgA:
undetectable		 4hdlA-2gfgA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6r TRIOSEPHOSPHATE
ISOMERASE

(Methanocaldococcus
jannaschii) 		PF00121
(TIM) 		4 ILE A 100
ILE A 135
LYS A  84
GLY A  85
 None
 0.76A 4hdlA-2h6rA:
undetectable		 4hdlA-2h6rA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ics ADENINE DEAMINASE

(Enterococcus
faecalis) 		PF01979
(Amidohydro_1) 		4 ILE A  24
ILE A 325
LYS A 309
GLY A 321
 None
 0.98A 4hdlA-2icsA:
undetectable		 4hdlA-2icsA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6l ALDEHYDE
DEHYDROGENASE FAMILY
7 MEMBER A1

(Homo sapiens) 		PF00171
(Aldedh) 		4 ILE A 386
ILE A 311
PHE A 409
GLY A 391
 None
 0.73A 4hdlA-2j6lA:
undetectable		 4hdlA-2j6lA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgp TYROCIDINE
SYNTHETASE 3

(Brevibacillus
brevis) 		PF00550
(PP-binding)
PF00668
(Condensation) 		4 LYS A   3
ILE A  72
PHE A  36
GLY A  40
 None
 0.91A 4hdlA-2jgpA:
undetectable		 4hdlA-2jgpA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjy ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE

(Francisella
tularensis) 		PF13561
(adh_short_C2) 		4 ILE A  87
ILE A  70
LYS A  79
GLY A  78
 None
 0.80A 4hdlA-2jjyA:
undetectable		 4hdlA-2jjyA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jmr FIMF

(Escherichia
coli) 		PF00419
(Fimbrial) 		4 ILE A 170
ILE A 104
MET A 133
GLY A  93
 None
 0.97A 4hdlA-2jmrA:
undetectable		 4hdlA-2jmrA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ILE A 253
ILE A 292
PHE A 290
GLY A 548
 None
 0.83A 4hdlA-2olsA:
undetectable		 4hdlA-2olsA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0o HYPOTHETICAL PROTEIN
DUF871

(Enterococcus
faecalis) 		PF05913
(DUF871) 		5 ILE A 101
ILE A 113
PHE A 135
LYS A 165
GLY A 168
 None
 1.50A 4hdlA-2p0oA:
undetectable		 4hdlA-2p0oA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwq UBIQUITIN
CONJUGATING ENZYME

(Plasmodium
yoelii) 		PF00179
(UQ_con) 		4 ILE A  14
LYS A  69
ILE A  38
PHE A  37
 None
 0.87A 4hdlA-2pwqA:
undetectable		 4hdlA-2pwqA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyg RIBULOSE
BISPHOSPHATE
CARBOXYLASE-LIKE
PROTEIN 2

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 ILE A 135
ILE A 109
PHE A 105
GLY A 103
 None
 0.93A 4hdlA-2qygA:
undetectable		 4hdlA-2qygA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtb FATTY ACID
MULTIFUNCTIONAL
PROTEIN (ATMFP2)

(Arabidopsis
thaliana) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ILE A 678
ILE A 671
PHE A 673
GLY A 285
 None
 0.76A 4hdlA-2wtbA:
undetectable		 4hdlA-2wtbA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0j COLD SHOCK PROTEIN

(Thermus
thermophilus) 		PF00313
(CSD) 		5 LYS A  58
ILE A  18
PHE A   9
LYS A  13
GLY A  14
 None
 1.24A 4hdlA-3a0jA:
undetectable		 4hdlA-3a0jA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayn RHODOPSIN

(Todarodes
pacificus) 		PF00001
(7tm_1) 		4 ILE A 216
ILE A 266
PHE A 270
GLY A 119
 None
None
None
RET  A1000 ( 3.8A)
 0.75A 4hdlA-3aynA:
undetectable		 4hdlA-3aynA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ba0 MACROPHAGE
METALLOELASTASE

(Homo sapiens) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10) 		4 ILE A 355
LYS A 348
ILE A 332
PHE A 347
 None
 0.94A 4hdlA-3ba0A:
undetectable		 4hdlA-3ba0A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bws PROTEIN LP49

(Leptospira
interrogans) 		PF10282
(Lactonase) 		4 ILE A 331
LYS A 369
ILE A 350
GLY A 326
 None
 0.89A 4hdlA-3bwsA:
undetectable		 4hdlA-3bwsA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec1 YQEH GTPASE

(Geobacillus
stearothermophilus) 		PF01926
(MMR_HSR1) 		4 ILE A 156
LYS A 175
ILE A 179
GLY A 105
 None
 0.80A 4hdlA-3ec1A:
undetectable		 4hdlA-3ec1A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8w LACTOCOCCAL PROPHAGE
PS3 PROTEIN 05

(Staphylococcus
epidermidis) 		PF13420
(Acetyltransf_4) 		4 ILE A 104
ILE A 117
MET A  72
LYS A  77
 None
 0.79A 4hdlA-3g8wA:
undetectable		 4hdlA-3g8wA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A

([Clostridium]
symbiosum) 		PF01039
(Carboxyl_trans) 		4 LYS A 388
ILE A 385
MET A 350
GLY A 393
 None
 0.83A 4hdlA-3gf7A:
undetectable		 4hdlA-3gf7A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5o TRANSCRIPTIONAL
REGULATOR GNTR

(Chromobacterium
violaceum) 		PF13377
(Peripla_BP_3) 		4 ILE A 177
ILE A 189
PHE A 191
GLY A 193
 None
 0.84A 4hdlA-3h5oA:
undetectable		 4hdlA-3h5oA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I

(Cytophaga
hutchinsonii) 		PF00425
(Chorismate_bind) 		4 ILE A 418
ILE A 384
PHE A 394
GLY A 360
 None
 0.97A 4hdlA-3h9mA:
undetectable		 4hdlA-3h9mA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hee RIBOSE-5-PHOSPHATE
ISOMERASE

(Ruminiclostridium
thermocellum) 		PF02502
(LacAB_rpiB) 		4 ILE A 103
LYS A  15
ILE A   5
GLY A 107
 None
 0.98A 4hdlA-3heeA:
undetectable		 4hdlA-3heeA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		4 ILE A 287
ILE A 294
PHE A 292
GLY A 345
 None
 0.76A 4hdlA-3hxwA:
undetectable		 4hdlA-3hxwA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2) 		4 ILE A 765
ILE A 735
MET A 645
GLY A 649
 None
 0.87A 4hdlA-3ibjA:
undetectable		 4hdlA-3ibjA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju7 PUTATIVE
PLP-DEPENDENT
AMINOTRANSFERASE

(Bacillus cereus) 		PF01041
(DegT_DnrJ_EryC1) 		4 ILE A 200
ILE A  69
MET A 228
GLY A 229
 None
 0.76A 4hdlA-3ju7A:
undetectable		 4hdlA-3ju7A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kly PUTATIVE FORMATE
TRANSPORTER 1

(Vibrio cholerae) 		PF01226
(Form_Nir_trans) 		4 ILE A 210
LYS A  32
ILE A  38
GLY A  85
 None
BOG  A 282 ( 3.9A)
None
BOG  A 282 ( 4.3A)
 0.94A 4hdlA-3klyA:
undetectable		 4hdlA-3klyA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8d METHYLTRANSFERASE

(Bacillus
thuringiensis) 		PF08241
(Methyltransf_11) 		4 LYS A 104
ILE A  83
LYS A  92
GLY A  91
 None
 0.95A 4hdlA-3l8dA:
undetectable		 4hdlA-3l8dA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lcm PUTATIVE
OXIDOREDUCTASE

(Streptococcus
mutans) 		PF02525
(Flavodoxin_2) 		4 ILE A 166
ILE A 125
MET A  88
GLY A  87
 None
 0.83A 4hdlA-3lcmA:
undetectable		 4hdlA-3lcmA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n7k BOTULINUM NEUROTOXIN
TYPE C1

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 ILE A 940
ILE A 944
PHE A1009
GLY A1026
 None
 0.96A 4hdlA-3n7kA:
undetectable		 4hdlA-3n7kA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogg BOTULINUM NEUROTOXIN
TYPE D

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 ILE A1101
ILE A1207
PHE A1205
GLY A1203
 None
 0.94A 4hdlA-3oggA:
undetectable		 4hdlA-3oggA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p5n RIBOFLAVIN UPTAKE
PROTEIN

(Staphylococcus
aureus) 		PF12822
(ECF_trnsprt) 		4 ILE A 113
LYS A 167
ILE A 173
PHE A 175
 None
RBF  A 190 (-3.2A)
None
None
 0.98A 4hdlA-3p5nA:
undetectable		 4hdlA-3p5nA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ph3 RIBOSE-5-PHOSPHATE
ISOMERASE

(Ruminiclostridium
thermocellum) 		PF02502
(LacAB_rpiB) 		4 ILE A 103
LYS A  15
ILE A   5
GLY A 107
 None
 0.96A 4hdlA-3ph3A:
undetectable		 4hdlA-3ph3A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 ILE A 679
ILE A 527
PHE A 671
GLY A 304
 None
 0.85A 4hdlA-3poyA:
undetectable		 4hdlA-3poyA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN

(Bacillus
subtilis) 		PF04069
(OpuAC) 		4 ILE A 199
ILE A 223
LYS A 284
GLY A 283
 None
 0.97A 4hdlA-3ppoA:
undetectable		 4hdlA-3ppoA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2c LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 3

(Homo sapiens) 		PF13895
(Ig_2) 		4 ILE A  62
PHE A  60
LYS A  57
GLY A  58
 None
 0.76A 4hdlA-3q2cA:
undetectable		 4hdlA-3q2cA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1

(Staphylococcus
aureus) 		PF00905
(Transpeptidase) 		4 ILE A 375
ILE A 489
MET A 368
LYS A 551
 None
 0.80A 4hdlA-3q7zA:
undetectable		 4hdlA-3q7zA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtp ENOLASE 1

(Entamoeba
histolytica) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ILE A  93
ILE A 351
MET A 114
GLY A 111
 None
 0.98A 4hdlA-3qtpA:
undetectable		 4hdlA-3qtpA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rks HYDROXYNITRILASE

(Manihot
esculenta) 		PF00561
(Abhydrolase_1) 		4 ILE A  75
ILE A 203
PHE A 102
GLY A  83
 None
 0.85A 4hdlA-3rksA:
undetectable		 4hdlA-3rksA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wh9 ENDO-BETA-1,4-MANNAN
ASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 ILE A  80
ILE A 147
MET A 118
GLY A 117
 None
 0.97A 4hdlA-3wh9A:
undetectable		 4hdlA-3wh9A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		4 ILE A 209
ILE A 202
PHE A 204
GLY A 378
 None
 0.81A 4hdlA-3wv4A:
undetectable		 4hdlA-3wv4A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvn NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
halstedii) 		PF00501
(AMP-binding) 		4 ILE A 209
ILE A 202
PHE A 204
GLY A 378
 None
 0.83A 4hdlA-3wvnA:
undetectable		 4hdlA-3wvnA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1f REPLICATIVE DNA
HELICASE

(Helicobacter
pylori) 		PF03796
(DnaB_C) 		4 ILE A 384
LYS A 209
ILE A 440
PHE A 387
 None
FLC  A1474 (-3.2A)
None
None
 0.91A 4hdlA-4a1fA:
undetectable		 4hdlA-4a1fA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ee9 ENDOGLUCANASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		4 ILE A  83
ILE A  86
PHE A  48
GLY A  11
 None
 0.98A 4hdlA-4ee9A:
undetectable		 4hdlA-4ee9A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fvl COLLAGENASE 3

(Homo sapiens) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10) 		4 ILE A 346
ILE A 334
PHE A 349
LYS A 369
 None
 0.98A 4hdlA-4fvlA:
undetectable		 4hdlA-4fvlA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fvv NEUROTOXIN

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 ILE A1144
ILE A1211
PHE A1209
GLY A1207
 None
 0.96A 4hdlA-4fvvA:
undetectable		 4hdlA-4fvvA:
9.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hc3 PPCA

(Geobacter
sulfurreducens) 		no annotation 7 ILE A   4
LYS A  33
ILE A  38
PHE A  41
MET A  45
LYS A  49
GLY A  50
 HEM  A  72 (-4.4A)
DXC  A  75 ( 4.4A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.3A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.1A)
DXC  A  75 ( 3.7A)
 0.17A 4hdlA-4hc3A:
15.6		 4hdlA-4hc3A:
97.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		4 ILE B 541
LYS B 603
PHE B 600
GLY B 461
 None
 0.98A 4hdlA-4hxeB:
undetectable		 4hdlA-4hxeB:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inl SERINE PROTEASE SPLD

(Staphylococcus
aureus) 		PF13365
(Trypsin_2) 		4 ILE A 160
ILE A 105
PHE A 103
GLY A  17
 None
 0.97A 4hdlA-4inlA:
undetectable		 4hdlA-4inlA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k37 ANAEROBIC
SULFATASE-MATURATING
ENZYME

(Clostridium
perfringens) 		PF04055
(Radical_SAM)
PF13186
(SPASM)
PF13353
(Fer4_12) 		4 ILE A 237
LYS A 179
PHE A 181
GLY A 125
 CL  A 513 (-4.8A)
None
None
None
 0.90A 4hdlA-4k37A:
undetectable		 4hdlA-4k37A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kn5 METHYLTHIOADENOSINE
NUCLEOSIDASE

(Weissella
paramesenteroides) 		PF01048
(PNP_UDP_1) 		4 ILE A  38
ILE A  72
MET A   9
GLY A 216
 None
 0.94A 4hdlA-4kn5A:
undetectable		 4hdlA-4kn5A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI

(Pseudomonas
aeruginosa) 		PF13561
(adh_short_C2) 		4 ILE A  90
ILE A  73
LYS A  82
GLY A  81
 None
 0.83A 4hdlA-4nqzA:
undetectable		 4hdlA-4nqzA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4or1 INVASIN HOMOLOG
AAFB, MAJOR FIMBRIAL
SUBUNIT OF
AGGREGATIVE
ADHERENCE FIMBRIA II
AAFA CHIMERIC
CONSTRUCT

(Escherichia
coli) 		PF05775
(AfaD) 		4 ILE A  94
ILE A  38
PHE A  36
GLY A  88
 None
 0.97A 4hdlA-4or1A:
undetectable		 4hdlA-4or1A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pa1 INTEGRASE

(Feline
immunodeficiency
virus) 		PF00665
(rve) 		4 ILE A 164
ILE A  90
MET A  65
GLY A  78
 None
 0.93A 4hdlA-4pa1A:
undetectable		 4hdlA-4pa1A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qp0 ENDO-BETA-MANNANASE

(Rhizomucor
miehei) 		PF00150
(Cellulase) 		4 ILE A  78
ILE A 146
MET A 117
GLY A 116
 None
 0.98A 4hdlA-4qp0A:
undetectable		 4hdlA-4qp0A:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6v DI-/TRIPEPTIDE
TRANSPORTER

(Yersinia
enterocolitica) 		PF00854
(PTR2) 		4 ILE A 495
ILE A 377
PHE A 375
GLY A 427
 None
 0.92A 4hdlA-4w6vA:
undetectable		 4hdlA-4w6vA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wse PUTATIVE POLY(A)
POLYMERASE CATALYTIC
SUBUNIT

(Acanthamoeba
polyphaga
mimivirus) 		no annotation 4 ILE A 341
LYS A 373
ILE A 245
GLY A 346
 None
 0.89A 4hdlA-4wseA:
undetectable		 4hdlA-4wseA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ww3 RHODOPSIN

(Todarodes
pacificus) 		PF00001
(7tm_1) 		4 ILE A 216
ILE A 266
PHE A 270
GLY A 119
 None
None
None
RET  A 401 (-3.8A)
 0.76A 4hdlA-4ww3A:
undetectable		 4hdlA-4ww3A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xd0 TDP-3-AMINOQUINOVOSE
-N-FORMYLTRANSFERASE

(Providencia
alcalifaciens) 		PF00551
(Formyl_trans_N)
PF12796
(Ank_2) 		5 ILE A  90
ILE A  79
PHE A  76
LYS A   8
GLY A   7
 None
FON  A 402 (-4.0A)
None
T3F  A 403 (-3.2A)
None
 1.37A 4hdlA-4xd0A:
undetectable		 4hdlA-4xd0A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)

(Bacillus
halodurans) 		PF13407
(Peripla_BP_4) 		4 ILE A 258
ILE A 148
MET A 305
GLY A 144
 None
 0.87A 4hdlA-4yo7A:
undetectable		 4hdlA-4yo7A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az3 ABC-TYPE
TRANSPORTER,
PERIPLASMIC
COMPONENT

(Corynebacterium
glutamicum) 		PF01497
(Peripla_BP_2) 		4 ILE A 316
ILE A 250
MET A 297
GLY A 300
 None
None
HEM  A 401 (-4.0A)
None
 0.88A 4hdlA-5az3A:
undetectable		 4hdlA-5az3A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3i CYTOCHROME C PRIME

(Hydrogenophilus
thermoluteolus) 		PF01322
(Cytochrom_C_2) 		4 ILE A 113
PHE A 117
LYS A 122
GLY A 121
 None
 0.82A 4hdlA-5b3iA:
undetectable		 4hdlA-5b3iA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		5 ILE A 103
ILE A  84
PHE A  97
MET A 185
GLY A 184
 None
 1.27A 4hdlA-5bptA:
undetectable		 4hdlA-5bptA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqs 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Streptococcus
pneumoniae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ILE A 229
ILE A 222
PHE A 220
GLY A 312
 None
None
None
4VN  A 402 ( 3.9A)
 0.94A 4hdlA-5bqsA:
undetectable		 4hdlA-5bqsA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czy LEGIONELLA EFFECTOR
LEGAS4

(Legionella
pneumophila) 		PF00023
(Ank)
PF00856
(SET) 		4 ILE A 193
ILE A 223
PHE A 134
GLY A 252
 None
 0.97A 4hdlA-5czyA:
undetectable		 4hdlA-5czyA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e04 NUCLEOPROTEIN

(Andes
orthohantavirus) 		PF00846
(Hanta_nucleocap) 		4 ILE A 236
ILE A 379
PHE A 330
GLY A 388
 None
 0.79A 4hdlA-5e04A:
undetectable		 4hdlA-5e04A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e05 NUCLEOCAPSID PROTEIN

(Sin Nombre
orthohantavirus) 		PF00846
(Hanta_nucleocap) 		4 ILE A 236
ILE A 379
PHE A 330
GLY A 388
 None
 0.78A 4hdlA-5e05A:
undetectable		 4hdlA-5e05A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h0k UNCHARACTERIZED
PROTEIN

(Pedobacter
heparinus) 		PF16265
(DUF4918) 		4 ILE A 107
ILE A  74
PHE A  76
GLY A  61
 None
 0.98A 4hdlA-5h0kA:
undetectable		 4hdlA-5h0kA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxz BARBITURASE

(Rhodococcus
erythropolis) 		PF09663
(Amido_AtzD_TrzD) 		4 ILE A 255
ILE A 150
LYS A 107
GLY A 250
 None
 0.96A 4hdlA-5hxzA:
undetectable		 4hdlA-5hxzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i8i UREA AMIDOLYASE

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF01425
(Amidase)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 ILE A 428
ILE A 259
LYS A 433
GLY A 432
 None
 0.81A 4hdlA-5i8iA:
undetectable		 4hdlA-5i8iA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jfc NADH-DEPENDENT
FERREDOXIN:NADP
OXIDOREDUCTASE
SUBUNIT ALPHA

(Pyrococcus
furiosus) 		PF07992
(Pyr_redox_2)
PF14691
(Fer4_20) 		4 ILE L 426
ILE L 243
PHE L 244
GLY L 166
 None
 0.83A 4hdlA-5jfcL:
undetectable		 4hdlA-5jfcL:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m7r PROTEIN O-GLCNACASE

(Homo sapiens) 		PF07555
(NAGidase) 		4 ILE A 325
ILE A 131
LYS A 308
GLY A 309
 None
 0.90A 4hdlA-5m7rA:
undetectable		 4hdlA-5m7rA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owj TRIGGER FACTOR

(Escherichia
coli) 		no annotation 4 ILE A  24
ILE A  17
MET A  71
GLY A  68
 None
 0.87A 4hdlA-5owjA:
undetectable		 4hdlA-5owjA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ta1 GLYCOSIDE HYDROLASE

(Bacteroides
uniformis) 		no annotation 4 ILE A 361
ILE A 304
MET A 272
GLY A 240
 None
 0.87A 4hdlA-5ta1A:
undetectable		 4hdlA-5ta1A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpu PUTATIVE
UNCHARACTERIZED
PROTEIN

(Campylobacter
jejuni) 		PF05523
(FdtA) 		4 ILE A  61
ILE A  33
LYS A  93
GLY A  92
 None
 0.94A 4hdlA-5tpuA:
undetectable		 4hdlA-5tpuA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2g PENICILLIN-BINDING
PROTEIN 1A

(Haemophilus
influenzae) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB) 		4 ILE A 519
ILE A 478
MET A 501
GLY A 506
 None
SO4  A 903 (-4.6A)
None
None
 0.94A 4hdlA-5u2gA:
undetectable		 4hdlA-5u2gA:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(environmental
samples) 		PF00202
(Aminotran_3) 		4 ILE A 209
ILE A 247
MET A 220
GLY A 218
 None
LLP  A 274 ( 3.8A)
None
None
 0.93A 4hdlA-5uc7A:
undetectable		 4hdlA-5uc7A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvo PROTEIN O-GLCNACASE

(Homo sapiens) 		PF07555
(NAGidase) 		4 ILE A 325
ILE A 131
LYS A 308
GLY A 309
 None
 0.93A 4hdlA-5vvoA:
undetectable		 4hdlA-5vvoA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x62 CARNOSINE
N-METHYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF07942
(N2227) 		4 ILE A 391
ILE A 349
PHE A 358
GLY A 291
 None
 0.96A 4hdlA-5x62A:
undetectable		 4hdlA-5x62A:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b8d ELONGATION FACTOR G

(Haemophilus
influenzae) 		no annotation 4 ILE A  15
ILE A 138
PHE A 140
GLY A 274
 None
 0.97A 4hdlA-6b8dA:
undetectable		 4hdlA-6b8dA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bo0 MDBA PROTEIN

(Corynebacterium
matruchotii) 		no annotation 4 ILE A  85
LYS A 229
ILE A 226
GLY A 215
 None
 0.96A 4hdlA-6bo0A:
undetectable		 4hdlA-6bo0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bt4 S-LAYER PROTEIN SAP

(Bacillus
anthracis) 		no annotation 4 ILE A 200
LYS A 189
ILE A 129
GLY A  67
 None
 0.96A 4hdlA-6bt4A:
undetectable		 4hdlA-6bt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fxn BELIMUMAB HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 ILE D  70
ILE D  52
PHE D  29
GLY D  77
 None
 0.97A 4hdlA-6fxnD:
undetectable		 4hdlA-6fxnD:
undetectable