SIMILAR PATTERNS OF AMINO ACIDS FOR 4HC3_A_DXCA75

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.95A 4hc3A-1a9xB:
undetectable		 4hc3A-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cja PROTEIN
(ACTIN-FRAGMIN
KINASE)

(Physarum
polycephalum) 		PF09192
(Act-Frag_cataly) 		4 LEU A 255
PHE A 266
MET A 289
GLY A 191
 None
 1.01A 4hc3A-1cjaA:
undetectable		 4hc3A-1cjaA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		4 LEU A 289
PHE A 327
LYS A 278
GLY A 277
 None
 0.82A 4hc3A-1j5sA:
undetectable		 4hc3A-1j5sA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhd SULFATE
ADENYLYLTRANSFERASE

(Sulfur-oxidizing
endosymbiont of
Riftia
pachyptila) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 4hc3A-1jhdA:
undetectable		 4hc3A-1jhdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jjf ENDO-1,4-BETA-XYLANA
SE Z

(Ruminiclostridium
thermocellum) 		PF00756
(Esterase) 		4 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.87A 4hc3A-1jjfA:
undetectable		 4hc3A-1jjfA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		4 ILE A 673
LEU A 582
LYS A 663
GLY A 585
 None
 1.06A 4hc3A-1kb0A:
undetectable		 4hc3A-1kb0A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A 178
LEU A 180
MET A  98
GLY A  64
 None
 0.84A 4hc3A-1kfiA:
undetectable		 4hc3A-1kfiA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		4 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.85A 4hc3A-1kfwA:
undetectable		 4hc3A-1kfwA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne3 30S RIBOSOMAL
PROTEIN S28E

(Methanothermococcus
thermolithotrophicus) 		PF01200
(Ribosomal_S28e) 		4 ILE A  52
LEU A  53
MET A  44
GLY A  45
 None
 1.06A 4hc3A-1ne3A:
undetectable		 4hc3A-1ne3A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 357
LEU A 268
MET A 418
GLY A 416
 None
 1.02A 4hc3A-1pw4A:
undetectable		 4hc3A-1pw4A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE

(Salmonella
enterica) 		PF06180
(CbiK) 		4 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 0.98A 4hc3A-1qgoA:
undetectable		 4hc3A-1qgoA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA

(Paracoccus
denitrificans) 		PF00115
(COX1) 		4 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 1.02A 4hc3A-1qleA:
undetectable		 4hc3A-1qleA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yi7 BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		4 ILE A 516
LEU A 372
PHE A 380
GLY A 512
 None
 0.94A 4hc3A-1yi7A:
undetectable		 4hc3A-1yi7A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST

(Spinacia
oleracea) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.86A 4hc3A-2akjA:
undetectable		 4hc3A-2akjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		4 LEU A 337
PHE A 273
LYS A 317
GLY A 318
 None
 1.06A 4hc3A-2b0tA:
undetectable		 4hc3A-2b0tA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dmg KIAA1228 PROTEIN

(Homo sapiens) 		PF00168
(C2) 		4 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 0.92A 4hc3A-2dmgA:
undetectable		 4hc3A-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgc ACETOLACTATE
SYNTHASE, SMALL
SUBUNIT

(Thermotoga
maritima) 		PF01842
(ACT)
PF10369
(ALS_ss_C) 		4 ILE A 174
LYS A 158
PHE A 162
GLY A 138
 None
 0.74A 4hc3A-2fgcA:
undetectable		 4hc3A-2fgcA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fxv XANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Bacillus
subtilis) 		PF00156
(Pribosyltran) 		4 ILE A  38
LEU A   4
PHE A  25
LYS A  21
 None
 1.05A 4hc3A-2fxvA:
undetectable		 4hc3A-2fxvA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE

(Clostridium
acetobutylicum) 		PF08942
(DUF1919) 		4 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.83A 4hc3A-2g6tA:
undetectable		 4hc3A-2g6tA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 ILE A 208
LEU A 185
PHE A 135
GLY A 134
 None
 1.04A 4hc3A-2higA:
undetectable		 4hc3A-2higA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hr7 INSULIN RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 ILE A  13
LEU A  17
PHE A  46
GLY A  68
 None
None
GOL  A 610 (-4.9A)
None
 1.00A 4hc3A-2hr7A:
undetectable		 4hc3A-2hr7A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9e TRIOSEPHOSPHATE
ISOMERASE

(Tenebrio
molitor) 		PF00121
(TIM) 		4 ILE A  24
LEU A  27
PHE A 239
GLY A   8
 None
 1.00A 4hc3A-2i9eA:
undetectable		 4hc3A-2i9eA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ILE A 739
LEU A 735
PHE A 762
GLY A 755
 None
 0.91A 4hc3A-2olsA:
undetectable		 4hc3A-2olsA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q42 PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 2

(Arabidopsis
thaliana) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 ILE A   3
LEU A  17
MET A  98
LYS A  96
 None
 0.84A 4hc3A-2q42A:
undetectable		 4hc3A-2q42A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qoj INTRON-ENCODED DNA
ENDONUCLEASE I-ANII

(Aspergillus
nidulans) 		PF00961
(LAGLIDADG_1) 		4 ILE Z 131
LEU Z 177
PHE Z 144
GLY Z  15
 None
None
None
MG  Z 603 ( 3.5A)
 1.05A 4hc3A-2qojZ:
undetectable		 4hc3A-2qojZ:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qs8 XAA-PRO DIPEPTIDASE

(Alteromonas
macleodii) 		PF01979
(Amidohydro_1) 		4 LEU A  65
MET A 360
LYS A  20
GLY A  19
 None
 1.03A 4hc3A-2qs8A:
undetectable		 4hc3A-2qs8A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9h H(+)/CL(-) EXCHANGE
TRANSPORTER CLCA

(Escherichia
coli) 		PF00654
(Voltage_CLC) 		4 ILE A 402
LEU A 444
PHE A 348
GLY A 106
 None
None
None
CL  A   1 ( 3.8A)
 0.89A 4hc3A-2r9hA:
undetectable		 4hc3A-2r9hA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb9 HYPE PROTEIN

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 169
LEU A 170
LYS A 310
GLY A 241
 None
 1.06A 4hc3A-2rb9A:
undetectable		 4hc3A-2rb9A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4g MYOSIN HEAVY CHAIN,
SKELETAL MUSCLE,
ADULT

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 ILE M 532
LEU M 525
LYS M 567
GLY M 560
 None
 0.83A 4hc3A-2w4gM:
undetectable		 4hc3A-2w4gM:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		4 ILE A 116
LEU A 114
LYS A 125
GLY A  63
 None
 0.89A 4hc3A-2xn6A:
undetectable		 4hc3A-2xn6A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		4 LEU A 114
LYS A 125
PHE A 126
GLY A  63
 None
 1.05A 4hc3A-2xn6A:
undetectable		 4hc3A-2xn6A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zl5 58 KD CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 ILE A 330
LEU A 373
LYS A 391
GLY A 324
 None
None
ACT  A 521 (-2.9A)
ACT  A 521 (-3.4A)
 1.06A 4hc3A-2zl5A:
undetectable		 4hc3A-2zl5A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.93A 4hc3A-3b0hA:
undetectable		 4hc3A-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 166
LEU A 156
MET A 213
GLY A 210
 None
 0.74A 4hc3A-3coiA:
undetectable		 4hc3A-3coiA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		4 ILE A 253
LEU A 306
PHE A 295
GLY A  44
 None
 0.90A 4hc3A-3ez1A:
undetectable		 4hc3A-3ez1A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f3s LAMBDA-CRYSTALLIN
HOMOLOG

(Homo sapiens) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ILE A 179
LEU A 175
LYS A  33
GLY A   7
 None
 0.90A 4hc3A-3f3sA:
undetectable		 4hc3A-3f3sA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		4 ILE A 219
LEU A 188
PHE A 247
GLY A 169
 None
 0.78A 4hc3A-3g85A:
undetectable		 4hc3A-3g85A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0o BETA-GLUCANASE

(Fibrobacter
succinogenes) 		PF00722
(Glyco_hydro_16) 		4 ILE A 163
LEU A  12
PHE A 193
GLY A 195
 None
None
ACT  A 405 (-4.5A)
None
 1.06A 4hc3A-3h0oA:
undetectable		 4hc3A-3h0oA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0t FAB FRAGMENT, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU B  11
LYS B 126
PHE B 155
GLY B 183
 None
 0.97A 4hc3A-3h0tB:
undetectable		 4hc3A-3h0tB:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Parabacteroides
distasonis) 		PF13483
(Lactamase_B_3) 		4 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.98A 4hc3A-3kl7A:
undetectable		 4hc3A-3kl7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lom GERANYLTRANSTRANSFER
ASE

(Legionella
pneumophila) 		PF00348
(polyprenyl_synt) 		4 ILE A 296
LEU A 295
LYS A 224
GLY A 223
 None
 1.05A 4hc3A-3lomA:
undetectable		 4hc3A-3lomA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pua PHD FINGER PROTEIN 2

(Homo sapiens) 		PF02373
(JmjC) 		4 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.81A 4hc3A-3puaA:
undetectable		 4hc3A-3puaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82

(Tetrahymena
thermophila) 		PF01336
(tRNA_anti-codon) 		4 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.53A 4hc3A-3u4vA:
undetectable		 4hc3A-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsv XYLOSIDASE

(Thermoanaerobacterium
saccharolyticum) 		PF13229
(Beta_helix) 		4 ILE A 557
LEU A 555
LYS A 441
GLY A 440
 None
 1.00A 4hc3A-3vsvA:
undetectable		 4hc3A-3vsvA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w04 DWARF 88 ESTERASE

(Oryza sativa) 		PF12697
(Abhydrolase_6) 		4 ILE A 132
LEU A 129
PHE A 143
GLY A 145
 None
 0.99A 4hc3A-3w04A:
undetectable		 4hc3A-3w04A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1h L-SERYL-TRNA(SEC)
SELENIUM TRANSFERASE

(Aquifex
aeolicus) 		PF03841
(SelA) 		4 ILE A 123
LEU A 127
LYS A 286
GLY A 281
 None
None
LLP  A 285 ( 3.1A)
None
 1.01A 4hc3A-3w1hA:
undetectable		 4hc3A-3w1hA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w2i NADH-CYTOCHROME B5
REDUCTASE 3

(Sus scrofa) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 ILE A 162
LEU A 193
PHE A 179
GLY A 152
 None
None
None
NAD  A 302 (-3.3A)
 0.85A 4hc3A-3w2iA:
undetectable		 4hc3A-3w2iA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzi UNCHARACTERIZED
PROTEIN AF_1864

(Archaeoglobus
fulgidus) 		PF09620
(Cas_csx3) 		4 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.94A 4hc3A-3wziA:
undetectable		 4hc3A-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 LEU A 325
PHE A 501
MET A 447
GLY A 373
 None
 1.01A 4hc3A-4av6A:
undetectable		 4hc3A-4av6A:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 1.00A 4hc3A-4b7gA:
undetectable		 4hc3A-4b7gA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4df9 PUTATIVE PEPTIDASE

(Bacteroides
fragilis) 		PF09471
(Peptidase_M64)
PF16217
(M64_N) 		4 ILE A 128
LEU A 130
PHE A  95
GLY A  39
 None
 0.91A 4hc3A-4df9A:
undetectable		 4hc3A-4df9A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg8 PA1221

(Pseudomonas
aeruginosa) 		PF00501
(AMP-binding) 		4 ILE A  89
LEU A  56
MET A  34
GLY A 227
 None
 0.98A 4hc3A-4dg8A:
undetectable		 4hc3A-4dg8A:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dnx SULFATE
ADENYLYLTRANSFERASE

(Allochromatium
vinosum) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 4hc3A-4dnxA:
undetectable		 4hc3A-4dnxA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4en2 AP-1 COMPLEX SUBUNIT
MU-1

(Mus musculus) 		no annotation 4 ILE M 253
LEU M 214
LYS M 199
GLY M 196
 None
 0.81A 4hc3A-4en2M:
undetectable		 4hc3A-4en2M:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 ILE A 460
LEU A 464
LYS A 413
GLY A 414
 None
 1.03A 4hc3A-4f4cA:
undetectable		 4hc3A-4f4cA:
4.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hc3 PPCA

(Geobacter
sulfurreducens) 		no annotation 7 ILE A   4
LEU A   6
LYS A  37
PHE A  41
MET A  45
LYS A  49
GLY A  50
 HEM  A  72 (-4.4A)
HEM  A  74 ( 3.7A)
DXC  A  75 ( 2.6A)
DXC  A  75 ( 4.3A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.1A)
DXC  A  75 ( 3.7A)
 0.22A 4hc3A-4hc3A:
16.3		 4hc3A-4hc3A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcx ISOCITRATE
DEHYDROGENASE [NADP]

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		4 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.93A 4hc3A-4hcxA:
undetectable		 4hc3A-4hcxA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hn3 LMO1757 PROTEIN

(Listeria
monocytogenes) 		PF07537
(CamS) 		4 ILE A 356
LEU A 342
LYS A 280
GLY A 295
 None
 0.89A 4hc3A-4hn3A:
undetectable		 4hc3A-4hn3A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		4 ILE A 417
LEU A 385
MET A 359
GLY A 358
 None
 0.96A 4hc3A-4hwvA:
undetectable		 4hc3A-4hwvA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jyp HYDROLASE,
ALPHA/BETA FOLD
FAMILY PROTEIN

(Arabidopsis
thaliana) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.01A 4hc3A-4jypA:
undetectable		 4hc3A-4jypA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kma GM14141P

(Drosophila
melanogaster) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		4 ILE A 450
LEU A 448
PHE A 422
LYS A 363
 None
 1.06A 4hc3A-4kmaA:
undetectable		 4hc3A-4kmaA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4laf NAD(P)H
DEHYDROGENASE
(QUINONE)

(Pseudomonas sp.
WBC-3) 		PF03358
(FMN_red) 		4 ILE A 145
LEU A 138
PHE A 134
GLY A  81
 None
 0.98A 4hc3A-4lafA:
undetectable		 4hc3A-4lafA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4llr TRYPAREDOXIN
PEROXIDASE

(Trypanosoma
cruzi) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 LEU A  41
PHE A  43
MET A 113
LYS A 110
 None
 1.00A 4hc3A-4llrA:
undetectable		 4hc3A-4llrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4log MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN
AND NR2E3 PROTEIN
CHIMERIC CONSTRUCT

(Escherichia
coli;
Homo sapiens) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 ILE A  11
LEU A   9
LYS A  28
PHE A  29
 None
 1.02A 4hc3A-4logA:
undetectable		 4hc3A-4logA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lr4 HYPOTHETICAL PROTEIN

([Eubacterium]
rectale) 		no annotation 4 ILE A 164
LEU A 219
PHE A 197
GLY A 192
 None
 1.04A 4hc3A-4lr4A:
undetectable		 4hc3A-4lr4A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mb5 CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18)
PF16403
(DUF5011) 		4 ILE A 255
LEU A 305
MET A 309
GLY A 272
 None
 1.03A 4hc3A-4mb5A:
undetectable		 4hc3A-4mb5A:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 316
LEU A 313
PHE A 152
GLY A 250
 None
 0.87A 4hc3A-4o38A:
undetectable		 4hc3A-4o38A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdy AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Alicyclobacillus
acidocaldarius) 		PF01636
(APH) 		4 LEU A 299
LYS A 334
PHE A 338
GLY A 271
 None
None
None
SCN  A 409 ( 4.7A)
 1.01A 4hc3A-4pdyA:
undetectable		 4hc3A-4pdyA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r16 418AA LONG
HYPOTHETICAL
UDP-N-ACETYL-D-MANNO
SAMINURONIC ACID
DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 ILE A 370
PHE A 408
LYS A 387
GLY A 386
 None
 0.96A 4hc3A-4r16A:
undetectable		 4hc3A-4r16A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvh D-MYCAROSE
3-C-METHYLTRANSFERAS
E

(Streptomyces
argillaceus) 		PF08421
(Methyltransf_13)
PF08484
(Methyltransf_14)
PF13489
(Methyltransf_23) 		4 ILE A 322
LEU A 345
LYS A 330
GLY A 331
 None
None
3YN  A 503 (-2.9A)
None
 1.02A 4hc3A-4rvhA:
undetectable		 4hc3A-4rvhA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8g PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1891

(Streptococcus
agalactiae) 		PF13561
(adh_short_C2) 		4 ILE A 250
LEU A 242
LYS A 171
GLY A 192
 None
 0.79A 4hc3A-4u8gA:
undetectable		 4hc3A-4u8gA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5u CHITINASE

(Streptomyces
thermoviolaceus) 		no annotation 4 ILE B  74
LEU B  62
PHE B  57
GLY B 392
 None
 0.94A 4hc3A-4w5uB:
undetectable		 4hc3A-4w5uB:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y90 TRIOSEPHOSPHATE
ISOMERASE

(Deinococcus
radiodurans) 		PF00121
(TIM) 		4 ILE A 125
LEU A 123
LYS A   4
GLY A 201
 None
 0.84A 4hc3A-4y90A:
undetectable		 4hc3A-4y90A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7l CAS6B

(Methanococcus
maripaludis) 		PF17262
(DUF5328) 		4 ILE A 194
LEU A 148
PHE A 117
GLY A 213
 None
 0.97A 4hc3A-4z7lA:
undetectable		 4hc3A-4z7lA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF07678
(A2M_comp) 		4 ILE A1227
LEU A1231
PHE A1240
GLY A1279
 None
 1.01A 4hc3A-4ziuA:
undetectable		 4hc3A-4ziuA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		5 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.37A 4hc3A-5bptA:
undetectable		 4hc3A-5bptA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5btb AFR263CP

(Eremothecium
gossypii) 		PF08652
(RAI1) 		4 ILE A 219
LEU A  43
MET A  38
GLY A  25
 None
 1.06A 4hc3A-5btbA:
undetectable		 4hc3A-5btbA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c93 HISTIDINE KINASE

(Lactobacillus
plantarum) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		4 ILE A 459
LEU A 607
LYS A 503
MET A 586
 None
None
SO4  A 704 ( 3.8A)
None
 1.05A 4hc3A-5c93A:
undetectable		 4hc3A-5c93A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cbk SHHTL5

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.95A 4hc3A-5cbkA:
undetectable		 4hc3A-5cbkA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dnw SHKAI2IB

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.98A 4hc3A-5dnwA:
undetectable		 4hc3A-5dnwA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7r LMO0178 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 ILE E 321
LEU E 317
PHE E 346
GLY E 339
 None
 1.04A 4hc3A-5f7rE:
undetectable		 4hc3A-5f7rE:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fi0 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1
PROTEIN,PHOSPHATIDYL
INOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 361
LEU A 298
LYS A 382
GLY A 276
 None
 0.82A 4hc3A-5fi0A:
undetectable		 4hc3A-5fi0A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gmx CARBOXYLESTERASE

(uncultured
bacterium) 		PF00144
(Beta-lactamase) 		4 ILE A 294
LEU A 282
PHE A 324
GLY A  75
 None
 0.94A 4hc3A-5gmxA:
undetectable		 4hc3A-5gmxA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD

(Escherichia
coli;
Danio rerio) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		4 ILE A  10
LEU A   8
LYS A  27
PHE A  28
 None
 0.99A 4hc3A-5gppA:
undetectable		 4hc3A-5gppA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm9 MAMO PROTEASE DOMAIN

(Magnetospirillum
magneticum) 		PF13365
(Trypsin_2) 		4 ILE A 216
LEU A 108
MET A 111
GLY A  65
 None
 0.93A 4hc3A-5hm9A:
undetectable		 4hc3A-5hm9A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S9

(Pyrococcus
abyssi) 		PF00380
(Ribosomal_S9) 		4 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.79A 4hc3A-5jb3K:
undetectable		 4hc3A-5jb3K:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqv INSULIN
RECEPTOR,INSULIN
RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 ILE E  13
LEU E  17
PHE E  46
GLY E  68
 None
 1.05A 4hc3A-5kqvE:
undetectable		 4hc3A-5kqvE:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksd ATPASE 2, PLASMA
MEMBRANE-TYPE

(Arabidopsis
thaliana) 		PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase) 		4 ILE A 497
LEU A 625
MET A 585
GLY A 584
 None
 0.90A 4hc3A-5ksdA:
undetectable		 4hc3A-5ksdA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		4 ILE A 486
LEU A 490
PHE A 504
GLY A 555
 None
 0.75A 4hc3A-5me3A:
undetectable		 4hc3A-5me3A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npy FLAGELLAR BASAL BODY
PROTEIN

(Helicobacter
pylori) 		no annotation 4 ILE A 352
LEU A 310
PHE A 224
GLY A 280
 None
 1.01A 4hc3A-5npyA:
undetectable		 4hc3A-5npyA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oo7 SLA2

(Chaetomium
thermophilum) 		no annotation 4 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.90A 4hc3A-5oo7A:
undetectable		 4hc3A-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opj RHAMNOGALACTURONAN
LYASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 ILE A  90
LEU A 422
PHE A 393
LYS A 390
 None
 0.93A 4hc3A-5opjA:
undetectable		 4hc3A-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4z REPRESSOR OF RNA
POLYMERASE III
TRANSCRIPTION

(Citrus sinensis) 		PF09174
(Maf1) 		4 LEU A 141
PHE A 192
LYS A  27
GLY A  28
 None
 1.06A 4hc3A-5u4zA:
undetectable		 4hc3A-5u4zA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vc7 VCP-LIKE ATPASE

(Thermoplasma
acidophilum) 		PF00004
(AAA) 		4 ILE A 599
LEU A 596
PHE A 627
GLY A 609
 None
 1.01A 4hc3A-5vc7A:
undetectable		 4hc3A-5vc7A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xhu FERREDOXIN--NADP
REDUCTASE

(Bacillus
subtilis) 		no annotation 4 ILE A  84
LEU A  86
LYS A  45
GLY A  44
 None
None
FAD  A1000 (-2.8A)
FAD  A1000 (-3.3A)
 0.82A 4hc3A-5xhuA:
undetectable		 4hc3A-5xhuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6j NUCLEOPROTEIN

(Tomato spotted
wilt
orthotospovirus) 		PF01533
(Tospo_nucleocap) 		4 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.01A 4hc3A-5y6jA:
undetectable		 4hc3A-5y6jA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.93A 4hc3A-5ze4A:
undetectable		 4hc3A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bca A-KINASE ANCHOR
PROTEIN 13

(Homo sapiens) 		no annotation 4 ILE A2204
LEU A2227
PHE A2271
MET A2214
 None
 1.00A 4hc3A-6bcaA:
undetectable		 4hc3A-6bcaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eki CARBONIC ANHYDRASE

(Persephonella
marina) 		no annotation 4 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.89A 4hc3A-6ekiA:
undetectable		 4hc3A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f4f GLUTATHIONE
TRANSFERASE

(Trametes
versicolor) 		no annotation 4 ILE A  88
LEU A  91
LYS A  77
GLY A  62
 None
 0.94A 4hc3A-6f4fA:
undetectable		 4hc3A-6f4fA:
undetectable