SIMILAR PATTERNS OF AMINO ACIDS FOR 4HAJ_A_DXCA75_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE

(Trypanosoma
brucei) 		PF00162
(PGK) 		4 ILE A 239
LEU A 227
LYS A 219
GLY A 399
 None
None
3PG  A 423 ( 2.6A)
None
 0.82A 4hajA-13pkA:
undetectable		 4hajA-13pkA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.97A 4hajA-1a9xB:
undetectable		 4hajA-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1afp ANTIFUNGAL PROTEIN
FROM ASPERGILLUS
GIGANTEUS

(Aspergillus
giganteus) 		PF11402
(Antifungal_prot) 		4 ILE A  25
PHE A  42
LYS A  46
GLY A  47
 None
 1.02A 4hajA-1afpA:
undetectable		 4hajA-1afpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1air PECTATE LYASE C

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		5 ILE A  32
LEU A  52
PHE A  87
LYS A  46
GLY A  47
 None
 1.40A 4hajA-1airA:
undetectable		 4hajA-1airA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1by7 PROTEIN (PLASMINOGEN
ACTIVATOR
INHIBITOR-2)

(Homo sapiens) 		PF00079
(Serpin) 		5 ILE A 114
LEU A 407
PHE A 204
LYS A 207
GLY A 206
 None
 1.48A 4hajA-1by7A:
undetectable		 4hajA-1by7A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cm8 PHOSPHORYLATED MAP
KINASE P38-GAMMA

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 169
LEU A 159
MET A 216
GLY A 213
 None
 0.94A 4hajA-1cm8A:
undetectable		 4hajA-1cm8A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)

(Escherichia
coli) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		4 ILE B 180
LEU B 184
PHE B  12
GLY B 214
 None
 0.94A 4hajA-1cqiB:
undetectable		 4hajA-1cqiB:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT BETA

(Helicobacter
pylori) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 ILE B  93
LEU B 434
LYS B  83
GLY B 123
 None
 0.74A 4hajA-1e9yB:
undetectable		 4hajA-1e9yB:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp9 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
thermophilus) 		PF02446
(Glyco_hydro_77) 		4 ILE A 304
LEU A 262
PHE A 217
GLY A 297
 None
 0.87A 4hajA-1fp9A:
undetectable		 4hajA-1fp9A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0v PROTEINASE A

(Saccharomyces
cerevisiae) 		PF00026
(Asp) 		4 ILE A 221
LEU A 223
PHE A 194
GLY A 196
 None
 0.91A 4hajA-1g0vA:
undetectable		 4hajA-1g0vA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyg L-LACTATE/MALATE
DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 286
LEU A 288
MET A 182
GLY A 176
 None
 1.02A 4hajA-1hygA:
undetectable		 4hajA-1hygA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7p NADH-CYTOCHROME B5
REDUCTASE

(Rattus
norvegicus) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 ILE A 190
LEU A 221
PHE A 207
GLY A 180
 None
 0.95A 4hajA-1i7pA:
undetectable		 4hajA-1i7pA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		4 LEU A 289
PHE A 327
LYS A 278
GLY A 277
 None
 0.88A 4hajA-1j5sA:
undetectable		 4hajA-1j5sA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhd SULFATE
ADENYLYLTRANSFERASE

(Sulfur-oxidizing
endosymbiont of
Riftia
pachyptila) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.04A 4hajA-1jhdA:
undetectable		 4hajA-1jhdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jjf ENDO-1,4-BETA-XYLANA
SE Z

(Ruminiclostridium
thermocellum) 		PF00756
(Esterase) 		4 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.96A 4hajA-1jjfA:
undetectable		 4hajA-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		4 ILE A 673
LEU A 582
LYS A 663
GLY A 585
 None
 0.94A 4hajA-1kb0A:
undetectable		 4hajA-1kb0A:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A 178
LEU A 180
MET A  98
GLY A  64
 None
 0.80A 4hajA-1kfiA:
undetectable		 4hajA-1kfiA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		4 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.89A 4hajA-1kfwA:
undetectable		 4hajA-1kfwA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 ILE A 131
LEU A 109
LYS A 218
GLY A 214
 None
 0.96A 4hajA-1ms8A:
undetectable		 4hajA-1ms8A:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7m GERMLINE METAL
CHELATASE CATALYTIC
ANTIBODY, CHAIN L

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU L  11
LYS L 118
PHE L 147
GLY L 175
 None
 0.99A 4hajA-1n7mL:
undetectable		 4hajA-1n7mL:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oqj GLUCOCORTICOID
MODULATORY ELEMENT
BINDING PROTEIN-1

(Homo sapiens) 		PF01342
(SAND) 		4 ILE A  97
LEU A 156
PHE A 111
GLY A 115
 None
 0.97A 4hajA-1oqjA:
undetectable		 4hajA-1oqjA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 357
LEU A 268
MET A 418
GLY A 416
 None
 0.96A 4hajA-1pw4A:
undetectable		 4hajA-1pw4A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 ILE A 352
LEU A 354
PHE A 332
GLY A 422
 None
 0.48A 4hajA-1q5aA:
undetectable		 4hajA-1q5aA:
5.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf6 THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		4 ILE A 416
LEU A 470
MET A 518
GLY A 516
 None
None
None
AMP  A1002 (-3.0A)
 0.94A 4hajA-1qf6A:
undetectable		 4hajA-1qf6A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4v HYPOTHETICAL PROTEIN
AQ_328

(Aquifex
aeolicus) 		PF09123
(DUF1931) 		4 ILE A  79
LEU A  84
PHE A  60
MET A 135
 None
 0.98A 4hajA-1r4vA:
undetectable		 4hajA-1r4vA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)

(Synechococcus
elongatus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 ILE A 309
LEU A 314
PHE A 274
GLY A 273
 None
 1.02A 4hajA-1rblA:
undetectable		 4hajA-1rblA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ugj RIKEN CDNA
2310057J16 PROTEIN

(Mus musculus) 		PF08683
(CAMSAP_CKK) 		4 ILE A  23
LEU A  27
PHE A  67
GLY A  85
 None
 0.92A 4hajA-1ugjA:
undetectable		 4hajA-1ugjA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uky URIDYLATE KINASE

(Saccharomyces
cerevisiae) 		PF00406
(ADK) 		4 ILE A  80
LEU A  51
LYS A 158
GLY A  73
 None
ADP  A 206 (-4.9A)
None
ADP  A 206 ( 4.2A)
 0.97A 4hajA-1ukyA:
undetectable		 4hajA-1ukyA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III

(Schizosaccharomyces
pombe) 		PF00291
(PALP) 		4 ILE A 306
LEU A 178
PHE A 169
GLY A 173
 None
 0.94A 4hajA-1v71A:
undetectable		 4hajA-1v71A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrm HYPOTHETICAL PROTEIN
TM1553

(Thermotoga
maritima) 		PF02424
(ApbE) 		4 ILE A 158
LEU A 137
LYS A 168
GLY A 166
 None
 1.04A 4hajA-1vrmA:
undetectable		 4hajA-1vrmA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wza ALPHA-AMYLASE A

(Halothermothrix
orenii) 		PF00128
(Alpha-amylase) 		4 ILE A  56
LEU A  81
PHE A 111
GLY A 217
 None
 0.96A 4hajA-1wzaA:
undetectable		 4hajA-1wzaA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xe4 FEMX

(Weissella
viridescens) 		PF02388
(FemAB) 		4 ILE A 244
LEU A 246
PHE A 223
GLY A  31
 None
 0.87A 4hajA-1xe4A:
undetectable		 4hajA-1xe4A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzz INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Mus musculus) 		PF08709
(Ins145_P3_rec) 		4 ILE A  27
LEU A 193
PHE A 161
GLY A 158
 None
 0.96A 4hajA-1xzzA:
undetectable		 4hajA-1xzzA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y2f CELL DIVISION
PROTEIN ZIPA

(Escherichia
coli) 		PF04354
(ZipA_C) 		4 ILE A 108
LEU A  28
PHE A  70
GLY A  68
 None
None
None
WAI  A 300 ( 4.2A)
 0.95A 4hajA-1y2fA:
undetectable		 4hajA-1y2fA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfj DNA ADENINE
METHYLASE

(Escherichia
virus T4) 		PF02086
(MethyltransfD12) 		4 ILE A  55
LEU A 103
PHE A 123
GLY A 110
 None
 0.96A 4hajA-1yfjA:
undetectable		 4hajA-1yfjA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbp HYPOTHETICAL PROTEIN
VPA1032

(Vibrio
parahaemolyticus) 		PF07024
(ImpE) 		4 ILE A 156
LEU A 158
PHE A 194
GLY A 200
 None
 0.99A 4hajA-1zbpA:
undetectable		 4hajA-1zbpA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zch HYPOTHETICAL
OXIDOREDUCTASE YCND

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		4 ILE A 236
LEU A 240
PHE A 156
GLY A 110
 None
 0.90A 4hajA-1zchA:
undetectable		 4hajA-1zchA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zu4 FTSY

(Mycoplasma
mycoides) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 ILE A 326
LEU A 324
PHE A 341
GLY A 292
 None
 0.96A 4hajA-1zu4A:
undetectable		 4hajA-1zu4A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST

(Spinacia
oleracea) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.80A 4hajA-2akjA:
undetectable		 4hajA-2akjA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		4 LEU A 337
PHE A 273
LYS A 317
GLY A 318
 None
 0.92A 4hajA-2b0tA:
undetectable		 4hajA-2b0tA:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cs5 TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 4

(Homo sapiens) 		PF00595
(PDZ) 		4 ILE A  70
LEU A  98
PHE A  29
GLY A  27
 None
 0.96A 4hajA-2cs5A:
undetectable		 4hajA-2cs5A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyb TYROSYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF00579
(tRNA-synt_1b) 		4 ILE A 236
LEU A 308
MET A  51
GLY A  48
 None
 1.00A 4hajA-2cybA:
undetectable		 4hajA-2cybA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 ILE A 270
LEU A 351
MET A  53
GLY A  49
 None
 0.94A 4hajA-2cycA:
undetectable		 4hajA-2cycA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fca TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE

(Bacillus
subtilis) 		PF02390
(Methyltransf_4) 		4 ILE A  21
LEU A  93
PHE A 104
LYS A 110
 None
 0.80A 4hajA-2fcaA:
undetectable		 4hajA-2fcaA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgc ACETOLACTATE
SYNTHASE, SMALL
SUBUNIT

(Thermotoga
maritima) 		PF01842
(ACT)
PF10369
(ALS_ss_C) 		4 ILE A 174
LYS A 158
PHE A 162
GLY A 138
 None
 0.80A 4hajA-2fgcA:
undetectable		 4hajA-2fgcA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g76 D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A  21
LEU A  22
PHE A 302
GLY A  73
 None
 0.96A 4hajA-2g76A:
undetectable		 4hajA-2g76A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcz BETA-EXPANSIN 1A

(Zea mays) 		PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1) 		5 ILE X 152
LEU X 161
LYS X 225
PHE X 210
GLY X 208
 None
 1.10A 4hajA-2hczX:
undetectable		 4hajA-2hczX:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 ILE A 208
LEU A 185
PHE A 135
GLY A 134
 None
 0.98A 4hajA-2higA:
undetectable		 4hajA-2higA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7t CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
73 KDA SUBUNIT

(Homo sapiens) 		PF00753
(Lactamase_B)
PF07521
(RMMBL)
PF10996
(Beta-Casp) 		4 ILE A 167
LEU A  68
LYS A  90
GLY A  91
 None
 1.03A 4hajA-2i7tA:
undetectable		 4hajA-2i7tA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf3 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Escherichia
coli) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		4 ILE A 222
LEU A 260
PHE A 252
GLY A 166
 None
 1.00A 4hajA-2jf3A:
undetectable		 4hajA-2jf3A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l02 UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF10771
(DUF2582) 		4 ILE A  25
LEU A  28
LYS A  51
GLY A  11
 None
 0.98A 4hajA-2l02A:
undetectable		 4hajA-2l02A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq2 HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
HI1470

(Haemophilus
influenzae) 		PF00005
(ABC_tran) 		4 ILE C  62
LEU C  10
PHE C  12
GLY C  43
 None
 0.97A 4hajA-2nq2C:
undetectable		 4hajA-2nq2C:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nrj HBL B PROTEIN

(Bacillus cereus) 		PF05791
(Bacillus_HBL) 		4 ILE A 125
LYS A 307
PHE A 306
GLY A 116
 None
 0.82A 4hajA-2nrjA:
undetectable		 4hajA-2nrjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ILE A 739
LEU A 735
PHE A 762
GLY A 755
 None
 1.03A 4hajA-2olsA:
undetectable		 4hajA-2olsA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Archaeoglobus
fulgidus) 		PF00005
(ABC_tran) 		4 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.03A 4hajA-2onkA:
undetectable		 4hajA-2onkA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqa LUFFACULIN 1

(Luffa
acutangula) 		PF00161
(RIP) 		4 ILE A 153
LEU A 131
PHE A   4
LYS A  16
 None
 1.03A 4hajA-2oqaA:
undetectable		 4hajA-2oqaA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2peg HEMOGLOBIN SUBUNIT
BETA

(Trematomus
bernacchii) 		PF00042
(Globin) 		5 ILE B 110
LEU B 134
PHE B 133
MET B  78
GLY B  74
 None
 1.42A 4hajA-2pegB:
undetectable		 4hajA-2pegB:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q14 PHOSPHOHYDROLASE

(Bacteroides
thetaiotaomicron) 		PF01966
(HD) 		4 ILE A 288
LEU A 106
PHE A 280
GLY A  98
 None
 1.01A 4hajA-2q14A:
undetectable		 4hajA-2q14A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q27 OXALYL-COA
DECARBOXYLASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A  14
LEU A 147
MET A  99
GLY A  72
 None
 0.98A 4hajA-2q27A:
undetectable		 4hajA-2q27A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q42 PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 2

(Arabidopsis
thaliana) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 ILE A   3
LEU A  17
MET A  98
LYS A  96
 None
 0.83A 4hajA-2q42A:
undetectable		 4hajA-2q42A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgg 16S RRNA-PROCESSING
PROTEIN RIMM

(Acinetobacter
calcoaceticus) 		PF01782
(RimM)
PF05239
(PRC) 		4 ILE A  47
LEU A  17
LYS A  59
GLY A  25
 None
 0.78A 4hajA-2qggA:
undetectable		 4hajA-2qggA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqp LARGE CAPSID PROTEIN

(Providence
virus) 		PF03566
(Peptidase_A21) 		4 ILE A 205
LEU A 155
PHE A 461
GLY A 459
 None
 0.95A 4hajA-2qqpA:
undetectable		 4hajA-2qqpA:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r94 2-KETO-3-DEOXY-(6-PH
OSPHO-)GLUCONATE
ALDOLASE

(Thermoproteus
tenax) 		PF00701
(DHDPS) 		4 LEU A 225
PHE A 206
MET A  21
GLY A 212
 None
 1.02A 4hajA-2r94A:
undetectable		 4hajA-2r94A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9h H(+)/CL(-) EXCHANGE
TRANSPORTER CLCA

(Escherichia
coli) 		PF00654
(Voltage_CLC) 		4 ILE A 402
LEU A 444
PHE A 348
GLY A 106
 None
None
None
CL  A   1 ( 3.8A)
 0.91A 4hajA-2r9hA:
undetectable		 4hajA-2r9hA:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rex RHO-RELATED
GTP-BINDING PROTEIN
RHO6

(Homo sapiens) 		PF00071
(Ras) 		4 ILE B 155
LEU B 122
LYS B 106
GLY B  20
 None
 0.77A 4hajA-2rexB:
undetectable		 4hajA-2rexB:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 ILE A 124
LEU A 525
PHE A 152
GLY A 518
 None
 0.95A 4hajA-2vpwA:
undetectable		 4hajA-2vpwA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4g MYOSIN HEAVY CHAIN,
SKELETAL MUSCLE,
ADULT

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 ILE M 532
LEU M 525
LYS M 567
GLY M 560
 None
 0.82A 4hajA-2w4gM:
undetectable		 4hajA-2w4gM:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wq4 LECTIN

(Burkholderia
cenocepacia) 		no annotation 4 ILE A  21
LEU A  42
PHE A  88
GLY A  71
 None
 0.94A 4hajA-2wq4A:
undetectable		 4hajA-2wq4A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu5 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 ILE A  26
LEU A 419
PHE A 384
GLY A 382
 None
 0.97A 4hajA-2wu5A:
undetectable		 4hajA-2wu5A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		5 ILE A 116
LEU A 114
LYS A 125
PHE A 126
GLY A  63
 None
 1.14A 4hajA-2xn6A:
undetectable		 4hajA-2xn6A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvn ASPERGILLUS
FUMIGATUS CHITINASE
A1

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		4 ILE A  61
LEU A 119
PHE A 161
MET A 104
 None
 0.93A 4hajA-2xvnA:
undetectable		 4hajA-2xvnA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yd0 ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 ILE A 929
LEU A 658
PHE A 644
GLY A 676
 None
 0.80A 4hajA-2yd0A:
undetectable		 4hajA-2yd0A:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z36 CYTOCHROME P450 TYPE
COMPACTIN
3'',4''-HYDROXYLASE

(Nonomuraea
recticatena) 		PF00067
(p450) 		4 ILE A 134
LEU A 151
MET A 253
GLY A 257
 None
 1.00A 4hajA-2z36A:
undetectable		 4hajA-2z36A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 ILE A 647
LEU A 688
LYS A 389
GLY A 673
 None
 1.02A 4hajA-2zwaA:
undetectable		 4hajA-2zwaA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afe HYDROXYLASE,
PUTATIVE

(Mycobacterium
tuberculosis) 		PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 ILE A  16
LEU A  20
MET A 248
GLY A 247
 None
 0.99A 4hajA-3afeA:
undetectable		 4hajA-3afeA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aup BASIC 7S GLOBULIN

(Glycine max) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 ILE A 213
LEU A 387
LYS A 193
GLY A 194
 None
 1.04A 4hajA-3aupA:
undetectable		 4hajA-3aupA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.85A 4hajA-3b0hA:
undetectable		 4hajA-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgw DNAB-LIKE
REPLICATIVE HELICASE

(Bacillus phage
SPP1) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		4 ILE A 200
LEU A 390
PHE A 432
GLY A 430
 None
 0.85A 4hajA-3bgwA:
undetectable		 4hajA-3bgwA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh0 DNAB-LIKE
REPLICATIVE HELICASE

(Bacillus phage
SPP1) 		PF03796
(DnaB_C) 		4 ILE A 200
LEU A 390
PHE A 432
GLY A 430
 None
 0.85A 4hajA-3bh0A:
undetectable		 4hajA-3bh0A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c41 AMINO ACID ABC
TRANSPORTER (ARTP)

(Geobacillus
stearothermophilus) 		PF00005
(ABC_tran) 		4 ILE J  60
LEU J  65
PHE J  53
GLY J  56
 None
 0.94A 4hajA-3c41J:
undetectable		 4hajA-3c41J:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 166
LEU A 156
MET A 213
GLY A 210
 None
 0.80A 4hajA-3coiA:
undetectable		 4hajA-3coiA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dyt SORTING NEXIN-9

(Homo sapiens) 		PF00787
(PX)
PF10456
(BAR_3_WASP_bdg) 		4 ILE A 344
LYS A 366
PHE A 353
LYS A 288
 None
SO4  A 701 (-2.7A)
None
SO4  A 701 (-2.9A)
 1.03A 4hajA-3dytA:
undetectable		 4hajA-3dytA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dyt SORTING NEXIN-9

(Homo sapiens) 		PF00787
(PX)
PF10456
(BAR_3_WASP_bdg) 		4 ILE A 581
LEU A 585
LYS A 440
GLY A 439
 None
 0.93A 4hajA-3dytA:
undetectable		 4hajA-3dytA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		4 ILE A 253
LEU A 306
PHE A 295
GLY A  44
 None
 0.94A 4hajA-3ez1A:
undetectable		 4hajA-3ez1A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f3s LAMBDA-CRYSTALLIN
HOMOLOG

(Homo sapiens) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ILE A 179
LEU A 175
LYS A  33
GLY A   7
 None
 0.95A 4hajA-3f3sA:
undetectable		 4hajA-3f3sA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM
PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM

(Mus musculus;
Mus musculus) 		PF04916
(Phospholip_B)
PF04916
(Phospholip_B) 		4 ILE A 224
LEU B 349
LYS A 159
PHE A 163
 None
None
NAG  A  21 (-2.7A)
None
 0.94A 4hajA-3fgtA:
undetectable		 4hajA-3fgtA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Glutamicibacter
protophormiae) 		PF03644
(Glyco_hydro_85) 		4 ILE A 431
LEU A 433
PHE A 360
GLY A 519
 None
 0.96A 4hajA-3fhaA:
undetectable		 4hajA-3fhaA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		4 ILE A 219
LEU A 188
PHE A 247
GLY A 169
 None
 0.79A 4hajA-3g85A:
undetectable		 4hajA-3g85A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcw MALTOSE OPERON
TRANSCRIPTIONAL
REPRESSOR

(Staphylococcus
aureus) 		PF13377
(Peripla_BP_3) 		4 ILE A 189
LEU A 255
LYS A 199
GLY A 193
 None
 1.04A 4hajA-3hcwA:
undetectable		 4hajA-3hcwA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvu HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Bacillus
anthracis) 		PF00156
(Pribosyltran) 		4 ILE A  16
LEU A 128
LYS A  43
GLY A  44
 None
 0.99A 4hajA-3hvuA:
undetectable		 4hajA-3hvuA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzb CARBOHYDRATE BINDING
PROTEIN

(Flavobacterium
johnsoniae) 		no annotation 4 ILE A  82
LEU A  18
LYS A   7
GLY A  32
 None
 1.03A 4hajA-3hzbA:
undetectable		 4hajA-3hzbA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT ALPHA

(Moorella
thermoacetica) 		PF03598
(CdhC) 		4 ILE M 311
LEU M 313
LYS M 147
GLY M 325
 None
 1.00A 4hajA-3i04M:
undetectable		 4hajA-3i04M:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i12 D-ALANINE-D-ALANINE
LIGASE A

(Salmonella
enterica) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ILE A  67
LEU A  58
PHE A  10
GLY A  42
 None
 1.02A 4hajA-3i12A:
undetectable		 4hajA-3i12A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwa FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Desulfovibrio
vulgaris) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ILE A 194
LEU A 171
LYS A 213
GLY A 346
 None
 0.84A 4hajA-3iwaA:
undetectable		 4hajA-3iwaA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixc HEXAPEPTIDE
TRANSFERASE FAMILY
PROTEIN

(Anaplasma
phagocytophilum) 		PF00132
(Hexapep) 		4 ILE A  77
LEU A  89
MET A 102
GLY A 101
 None
 1.00A 4hajA-3ixcA:
undetectable		 4hajA-3ixcA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8p PROTEIN TRANSPORT
PROTEIN SEC39

(Saccharomyces
cerevisiae) 		PF08314
(Sec39) 		4 ILE D 182
LYS D 157
LYS D 226
GLY D 225
 None
 0.96A 4hajA-3k8pD:
undetectable		 4hajA-3k8pD:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ke6 PROTEIN
RV1364C/MT1410

(Mycobacterium
tuberculosis) 		PF07228
(SpoIIE)
PF13581
(HATPase_c_2) 		4 ILE A 438
LEU A 521
PHE A 445
GLY A 497
 None
 1.03A 4hajA-3ke6A:
undetectable		 4hajA-3ke6A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kjx TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Ruegeria
pomeroyi) 		PF00356
(LacI)
PF00532
(Peripla_BP_1) 		4 ILE A 275
LEU A 277
LYS A 231
GLY A 232
 None
 0.76A 4hajA-3kjxA:
undetectable		 4hajA-3kjxA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Parabacteroides
distasonis) 		PF13483
(Lactamase_B_3) 		4 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.92A 4hajA-3kl7A:
undetectable		 4hajA-3kl7A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3knt N-GLYCOSYLASE/DNA
LYASE

(Methanocaldococcus
jannaschii) 		no annotation 4 ILE A  93
LEU A  78
LYS A  60
GLY A  54
 None
 0.86A 4hajA-3kntA:
undetectable		 4hajA-3kntA:
14.98