SIMILAR PATTERNS OF AMINO ACIDS FOR 4GCP_A_AICA401_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gfn | MATRIX PORIN OUTERMEMBRANE PROTEIN F (Escherichiacoli) |
PF00267(Porin_1) | 5 | TYR A 22GLY A 34SER A 125ARG A 167ARG A 168 | None | 1.17A | 4gcpA-1gfnA:44.9 | 4gcpA-1gfnA:98.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gfn | MATRIX PORIN OUTERMEMBRANE PROTEIN F (Escherichiacoli) |
PF00267(Porin_1) | 7 | TYR A 22TYR A 32GLY A 33TYR A 124SER A 125ARG A 167ARG A 168 | None | 0.36A | 4gcpA-1gfnA:44.9 | 4gcpA-1gfnA:98.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gju | MALTODEXTRINGLYCOSYLTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09083(DUF1923) | 5 | TYR A 498TYR A 138GLY A 88ASP A 201ARG A 92 | None | 1.48A | 4gcpA-1gjuA:0.0 | 4gcpA-1gjuA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p76 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Staphylococcusaureus) |
PF03009(GDPD) | 5 | TYR A 65GLY A 64PHE A 300ASP A 302SER A 84 | None | 1.18A | 4gcpA-2p76A:0.0 | 4gcpA-2p76A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzt | GLUTAMATE--CYSTEINELIGASE (Francisellatularensis) |
PF04262(Glu_cys_ligase) | 5 | TYR A 254GLY A 272TYR A 281SER A 282ARG A 285 | NoneNoneNoneNoneSO4 A 506 (-2.9A) | 1.47A | 4gcpA-3nztA:0.0 | 4gcpA-3nztA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ox2 | PHOSPHOENOLPYRUVATECARBOXYKINASE,CYTOSOLIC [GTP] (Rattusnorvegicus) |
PF00821(PEPCK_C)PF17297(PEPCK_N) | 5 | TYR A 235GLY A 236PHE A 333ASP A 311ARG A 483 | NoneSPV A 704 ( 3.8A)SPV A 704 (-4.9A) MN A 701 (-2.5A)None | 1.36A | 4gcpA-4ox2A:0.0 | 4gcpA-4ox2A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rhm | ARGINASE (Trypanosomabrucei) |
PF00491(Arginase) | 5 | TYR A 267GLY A 124ASP A 149SER A 155ARG A 162 | NoneNone MN A 402 (-2.5A)NoneNone | 1.44A | 4gcpA-4rhmA:0.0 | 4gcpA-4rhmA:20.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fvn | OMPC PORIN (Enterobactercloacae) |
PF00267(Porin_1) | 5 | TYR A 22PHE A 110ASP A 113SER A 117ARG A 170 | NoneC8E A 407 (-4.6A)C8E A 407 (-3.3A)PO4 A 411 (-2.6A)PO4 A 411 (-3.1A) | 0.90A | 4gcpA-5fvnA:43.6 | 4gcpA-5fvnA:61.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fvn | OMPC PORIN (Enterobactercloacae) |
PF00267(Porin_1) | 5 | TYR A 22PHE A 110ASP A 113SER A 117ARG A 170 | NoneC8E A 407 (-4.6A)C8E A 407 (-3.3A)PO4 A 411 (-2.6A)PO4 A 411 (-3.1A) | 1.43A | 4gcpA-5fvnA:43.6 | 4gcpA-5fvnA:61.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vk2 | FAB 37.7H HEAVYCHAINPRE-GLYCOPROTEINPOLYPROTEIN GPCOMPLEX (Homo sapiens;Lassamammarenavirus) |
PF00798(Arena_glycoprot)PF07654(C1-set)PF07686(V-set) | 5 | GLY a 294ASP a 273TYR D 33SER D 31ARG D 55 | None | 1.07A | 4gcpA-5vk2a:0.0 | 4gcpA-5vk2a:17.97 |