SIMILAR PATTERNS OF AMINO ACIDS FOR 4G1B_D_ECND403_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6m | DNA TOPOISOMERASEIII (Escherichiacoli) |
PF01131(Topoisom_bac)PF01751(Toprim) | 5 | ILE A 351GLN A 409LEU A 411VAL A 364ILE A 368 | None | 1.12A | 4g1bD-1d6mA:3.3 | 4g1bD-1d6mA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dly | HEMOGLOBIN (Chlamydomonasmoewusii) |
PF01152(Bac_globin) | 5 | PHE A 19TYR A 20PHE A 33LEU A 49LEU A 87 | NoneCYN A 122 (-4.3A)HEM A 144 ( 4.4A)NoneNone | 1.15A | 4g1bD-1dlyA:10.0 | 4g1bD-1dlyA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0r | THERMOSOME (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 5 | ILE B 334GLN B 292LEU B 240VAL B 289LEU B 244 | None | 1.15A | 4g1bD-1e0rB:undetectable | 4g1bD-1e0rB:17.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gvh | FLAVOHEMOPROTEIN (Escherichiacoli) |
PF00042(Globin)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 6 | THR A 25PHE A 28TYR A 29PHE A 43LEU A 102TYR A 124 | NoneNoneNoneHEM A1398 (-3.9A)NoneHEM A1398 ( 4.9A) | 0.64A | 4g1bD-1gvhA:44.0 | 4g1bD-1gvhA:36.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gvz | KALLIKREIN-1E2 (Equus caballus) |
PF00089(Trypsin) | 5 | ILE A 66GLN A 110LEU A 108LEU A 68ILE A 114 | None | 1.01A | 4g1bD-1gvzA:undetectable | 4g1bD-1gvzA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 5 | ILE A 481THR A 482PHE A 491LEU A 476ILE A 323 | NoneNoneNoneLPP A 1 (-4.2A)None | 0.99A | 4g1bD-1hg4A:undetectable | 4g1bD-1hg4A:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkf | NK CELL ACTIVATINGRECEPTOR (Homo sapiens) |
PF07686(V-set) | 5 | ILE A 65THR A 64PHE A 63VAL A 20TYR A 89 | None | 1.13A | 4g1bD-1hkfA:undetectable | 4g1bD-1hkfA:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl7 | MONOMER HEMOGLOBINCOMPONENT III (Glyceradibranchiata) |
PF00042(Globin) | 5 | PHE A 45LEU A 63LEU A 110TYR A 134ILE A 137 | HEM A 148 (-3.7A)NoneNoneNoneNone | 0.64A | 4g1bD-1jl7A:16.7 | 4g1bD-1jl7A:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olt | OXYGEN-INDEPENDENTCOPROPORPHYRINOGENIII OXIDASE (Escherichiacoli) |
PF04055(Radical_SAM)PF06969(HemN_C) | 5 | PHE A 284GLN A 4LEU A 277TYR A 212ILE A 269 | None | 1.10A | 4g1bD-1oltA:undetectable | 4g1bD-1oltA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t9h | PROBABLE GTPASE ENGC (Bacillussubtilis) |
PF03193(RsgA_GTPase)PF16745(RsgA_N) | 5 | THR A 241PHE A 242PHE A 287TYR A 137ILE A 113 | None | 1.11A | 4g1bD-1t9hA:4.6 | 4g1bD-1t9hA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdu | TRAS1 ORF2P (Bombyx mori) |
PF14529(Exo_endo_phos_2) | 5 | ILE A 88TYR A 125LEU A 53VAL A 25ILE A 223 | None | 1.10A | 4g1bD-1wduA:undetectable | 4g1bD-1wduA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xhb | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 1 (Mus musculus) |
PF00535(Glycos_transf_2)PF00652(Ricin_B_lectin) | 5 | ILE A 434GLN A 441LEU A 443VAL A 454LEU A 524 | None | 0.95A | 4g1bD-1xhbA:2.5 | 4g1bD-1xhbA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eh0 | KINESIN-LIKE PROTEINKIF1B (Homo sapiens) |
PF00498(FHA)PF16183(Kinesin_assoc) | 5 | ILE A 101PHE A 111GLN A 94LEU A 74ILE A 32 | None | 1.03A | 4g1bD-2eh0A:undetectable | 4g1bD-2eh0A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fm8 | SURFACE PRESENTATIONOF ANTIGENS PROTEINSPAK (Salmonellaenterica) |
PF03519(Invas_SpaK) | 5 | ILE A 54LEU A 119VAL A 10LEU A 35ILE A 24 | None | 1.15A | 4g1bD-2fm8A:undetectable | 4g1bD-2fm8A:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fus | FUMARASE C (Escherichiacoli) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 5 | ILE A 215GLN A 163LEU A 164LEU A 284ILE A 291 | None | 1.14A | 4g1bD-2fusA:undetectable | 4g1bD-2fusA:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i14 | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Pyrococcusfuriosus) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ILE A 265PHE A 266PHE A 134LEU A 234VAL A 208 | NoneNonePCP A 392 (-4.2A)NoneNone | 1.07A | 4g1bD-2i14A:undetectable | 4g1bD-2i14A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2icu | HYPOTHETICAL PROTEINYEDK (Escherichiacoli) |
PF02586(SRAP) | 5 | ILE A 154PHE A 124VAL A 51TYR A 21ILE A 40 | None | 1.10A | 4g1bD-2icuA:undetectable | 4g1bD-2icuA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixm | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AREGULATORY SUBUNITB' (Homo sapiens) |
PF03095(PTPA) | 5 | ILE A 180PHE A 185LEU A 55TYR A 48ILE A 49 | None | 1.01A | 4g1bD-2ixmA:undetectable | 4g1bD-2ixmA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lvw | ACETOLACTATESYNTHASE ISOZYME 1SMALL SUBUNIT (Escherichiacoli) |
PF01842(ACT) | 5 | ILE A 71GLN A 81LEU A 15THR A 16VAL A 17 | None | 1.15A | 4g1bD-2lvwA:undetectable | 4g1bD-2lvwA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2npn | PUTATIVE COBALAMINSYNTHESIS RELATEDPROTEIN (Corynebacteriumdiphtheriae) |
PF00590(TP_methylase) | 5 | ILE A 121THR A 118LEU A 34VAL A 63LEU A 90 | None | 1.15A | 4g1bD-2npnA:2.1 | 4g1bD-2npnA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1o | PUTATIVE FARNESYLPYROPHOSPHATESYNTHASE (Cryptosporidiumparvum) |
PF00348(polyprenyl_synt) | 6 | ILE A 169PHE A 161LEU A 100VAL A 103LEU A 157ILE A 38 | None | 1.32A | 4g1bD-2o1oA:undetectable | 4g1bD-2o1oA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odl | ADHESIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 5 | ILE A 310LEU A 301VAL A 275LEU A 286ILE A 231 | None | 1.15A | 4g1bD-2odlA:undetectable | 4g1bD-2odlA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qt5 | GLUTAMATERECEPTOR-INTERACTINGPROTEIN 1 (Rattusnorvegicus) |
PF00595(PDZ) | 5 | ILE A 101GLN A 94LEU A 130VAL A 128LEU A 66 | None | 1.09A | 4g1bD-2qt5A:undetectable | 4g1bD-2qt5A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9y | ALPHA-2-ANTIPLASMIN (Mus musculus) |
PF00079(Serpin) | 5 | ILE A 133PHE A 159GLN A 126LEU A 128LEU A 84 | None | 1.02A | 4g1bD-2r9yA:undetectable | 4g1bD-2r9yA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsm | HEMAGGLUTININ-NEURAMINIDASE (Nipahhenipavirus) |
PF00423(HN) | 5 | ILE A 431THR A 471VAL A 469LEU A 413TYR A 363 | None | 1.14A | 4g1bD-2vsmA:undetectable | 4g1bD-2vsmA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnk | SPOROZOITE-SPECIFICSAG PROTEIN (Toxoplasmagondii) |
PF04092(SAG) | 5 | TYR A 39LEU A 84THR A 85VAL A 86LEU A 59 | None | 1.10A | 4g1bD-2wnkA:undetectable | 4g1bD-2wnkA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy4 | SINGLE DOMAINHAEMOGLOBIN (Campylobacterjejuni) |
PF00042(Globin) | 6 | PHE A 27TYR A 28GLN A 52LEU A 101TYR A 123ILE A 126 | NoneCYN A 151 (-4.7A)HEM A 150 ( 3.6A)NoneNoneHEM A 150 ( 4.8A) | 0.86A | 4g1bD-2wy4A:20.9 | 4g1bD-2wy4A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy4 | SINGLE DOMAINHAEMOGLOBIN (Campylobacterjejuni) |
PF00042(Globin) | 5 | PHE A 27TYR A 28LEU A 23LEU A 101TYR A 123 | NoneCYN A 151 (-4.7A)NoneNoneNone | 1.12A | 4g1bD-2wy4A:20.9 | 4g1bD-2wy4A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy4 | SINGLE DOMAINHAEMOGLOBIN (Campylobacterjejuni) |
PF00042(Globin) | 6 | PHE A 27TYR A 28PHE A 42LEU A 101TYR A 123ILE A 126 | NoneCYN A 151 (-4.7A)HEM A 150 ( 3.5A)NoneNoneHEM A 150 ( 4.8A) | 0.78A | 4g1bD-2wy4A:20.9 | 4g1bD-2wy4A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy4 | SINGLE DOMAINHAEMOGLOBIN (Campylobacterjejuni) |
PF00042(Globin) | 5 | THR A 24PHE A 27TYR A 28GLN A 52TYR A 123 | NoneNoneCYN A 151 (-4.7A)HEM A 150 ( 3.6A)None | 0.89A | 4g1bD-2wy4A:20.9 | 4g1bD-2wy4A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wy4 | SINGLE DOMAINHAEMOGLOBIN (Campylobacterjejuni) |
PF00042(Globin) | 5 | THR A 24PHE A 27TYR A 28PHE A 42TYR A 123 | NoneNoneCYN A 151 (-4.7A)HEM A 150 ( 3.5A)None | 0.83A | 4g1bD-2wy4A:20.9 | 4g1bD-2wy4A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xh1 | KYNURENINE/ALPHA-AMINOADIPATEAMINOTRANSFERASE,MITOCHONDRIAL (Homo sapiens) |
PF00155(Aminotran_1_2) | 5 | ILE A 421GLN A 415LEU A 417LEU A 341ILE A 333 | None | 1.07A | 4g1bD-2xh1A:undetectable | 4g1bD-2xh1A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ysk | HYPOTHETICAL PROTEINTTHA1432 (Thermusthermophilus) |
PF10025(DUF2267) | 5 | ILE A 23PHE A 89LEU A 39VAL A 66LEU A 118 | None | 1.14A | 4g1bD-2yskA:undetectable | 4g1bD-2yskA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqg | ZYMOGEN GRANULEPROTEIN 16 HOMOLOG B (Homo sapiens) |
PF01419(Jacalin) | 5 | ILE A 179GLN A 127LEU A 130VAL A 86TYR A 144 | None | 1.14A | 4g1bD-3aqgA:undetectable | 4g1bD-3aqgA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c1x | HEPATOCYTE GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | THR A1126GLN A1123LEU A1125LEU A1058ILE A1053 | None | 1.13A | 4g1bD-3c1xA:undetectable | 4g1bD-3c1xA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwx | PROTEIN CAGD (Helicobacterpylori) |
PF16567(CagD) | 5 | ILE A 166LEU A 122LEU A 137TYR A 138ILE A 62 | None | 1.15A | 4g1bD-3cwxA:undetectable | 4g1bD-3cwxA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dv9 | BETA-PHOSPHOGLUCOMUTASE (Bacteroidesvulgatus) |
PF13419(HAD_2) | 5 | PHE A 230PHE A 25LEU A 222LEU A 237ILE A 18 | None | 1.13A | 4g1bD-3dv9A:5.1 | 4g1bD-3dv9A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3et5 | OUTER MEMBRANEPROTEIN P4, NADPPHOSPHATASE (Haemophilusinfluenzae) |
PF03767(Acid_phosphat_B) | 5 | ILE A 214PHE A 213LEU A 177VAL A 61ILE A 168 | None | 1.03A | 4g1bD-3et5A:3.4 | 4g1bD-3et5A:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg4 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | ILE A 649LEU A 645VAL A 635LEU A 624ILE A 726 | None | 1.14A | 4g1bD-3fg4A:2.2 | 4g1bD-3fg4A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7n | NUCLEOPORIN NUP120 (Saccharomycescerevisiae) |
PF11715(Nup160) | 6 | TYR A 701PHE A 692LEU A 679VAL A 678LEU A 616TYR A 14 | None | 1.48A | 4g1bD-3h7nA:undetectable | 4g1bD-3h7nA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42 (Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 5 | ILE A1771LEU A1560THR A1559LEU A1597ILE A1590 | None | 1.14A | 4g1bD-3jb9A:undetectable | 4g1bD-3jb9A:10.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n9x | PHOSPHOTRANSFERASE (Plasmodiumberghei) |
PF00069(Pkinase) | 6 | ILE A 241THR A 238PHE A 242LEU A 138VAL A 168LEU A 245 | None | 1.17A | 4g1bD-3n9xA:undetectable | 4g1bD-3n9xA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nie | MAP2 KINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 6 | ILE A 246THR A 243PHE A 247LEU A 140VAL A 170LEU A 250 | None | 1.18A | 4g1bD-3nieA:undetectable | 4g1bD-3nieA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o90 | NICOTINAMIDASE (Streptococcuspneumoniae) |
PF00857(Isochorismatase) | 5 | ILE A 52THR A 51PHE A 50VAL A 131ILE A 30 | None | 1.13A | 4g1bD-3o90A:6.7 | 4g1bD-3o90A:19.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 7 | ILE B 24PHE B 28TYR B 29PHE B 43LEU B 57LEU B 102TYR B 126 | ECN B 411 (-3.5A)ECN B 411 (-4.0A)NoneHEM B 404 ( 3.8A)ECN B 411 (-4.1A)ECN B 411 (-3.2A)HEM B 404 ( 3.9A) | 0.90A | 4g1bD-3ozvB:46.8 | 4g1bD-3ozvB:37.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 6 | ILE B 24PHE B 28TYR B 29PHE B 43LEU B 57VAL B 61 | ECN B 411 (-3.5A)ECN B 411 (-4.0A)NoneHEM B 404 ( 3.8A)ECN B 411 (-4.1A)DGG B 406 ( 4.8A) | 0.90A | 4g1bD-3ozvB:46.8 | 4g1bD-3ozvB:37.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 5 | PHE B 28PHE B 43GLN B 53LEU B 102TYR B 126 | ECN B 411 (-4.0A)HEM B 404 ( 3.8A)HEM B 404 (-3.9A)ECN B 411 (-3.2A)HEM B 404 ( 3.9A) | 1.14A | 4g1bD-3ozvB:46.8 | 4g1bD-3ozvB:37.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3phu | RNA-DIRECTED RNAPOLYMERASE L (Crimean-Congohemorrhagicfeverorthonairovirus) |
PF02338(OTU) | 5 | ILE A 31PHE A 29LEU A 145THR A 120VAL A 121 | None | 0.96A | 4g1bD-3phuA:undetectable | 4g1bD-3phuA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pse | RNA POLYMERASE (Crimean-Congohemorrhagicfeverorthonairovirus) |
PF02338(OTU) | 5 | ILE A 31PHE A 29LEU A 145THR A 120VAL A 121 | None | 0.98A | 4g1bD-3pseA:undetectable | 4g1bD-3pseA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdq | 4-HYDROXYBUTYRATECOA-TRANSFERASE (Clostridiumaminobutyricum) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 6 | ILE A 267THR A 268LEU A 288VAL A 162LEU A 270TYR A 277 | None | 1.31A | 4g1bD-3qdqA:3.2 | 4g1bD-3qdqA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qml | NUCLEOTIDE EXCHANGEFACTOR SIL1 (Saccharomycescerevisiae) |
PF16782(SIL1) | 5 | ILE C 244LEU C 248VAL C 286TYR C 264ILE C 293 | None | 1.06A | 4g1bD-3qmlC:undetectable | 4g1bD-3qmlC:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2s | PUTATIVEPYRAZINAMIDASE/NICOTINAMIDASE (Streptococcusmutans) |
PF00857(Isochorismatase) | 5 | ILE A 52THR A 51PHE A 50VAL A 131ILE A 30 | None | 1.10A | 4g1bD-3s2sA:6.7 | 4g1bD-3s2sA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tm9 | BACTERIAL HEMOGLOBIN (Vitreoscillastercoraria) |
PF00042(Globin) | 7 | ILE A 24THR A 25PHE A 28PHE A 43LEU A 102TYR A 126ILE A 129 | NoneNoneNoneHEM A 201 (-3.1A)NoneHEM A 201 (-3.5A)HEM A 201 ( 4.6A) | 0.82A | 4g1bD-3tm9A:19.9 | 4g1bD-3tm9A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tm9 | BACTERIAL HEMOGLOBIN (Vitreoscillastercoraria) |
PF00042(Globin) | 7 | ILE A 24THR A 25PHE A 43THR A 60LEU A 102TYR A 126ILE A 129 | NoneNoneHEM A 201 (-3.1A)HEM A 201 (-2.5A)NoneHEM A 201 (-3.5A)HEM A 201 ( 4.6A) | 1.06A | 4g1bD-3tm9A:19.9 | 4g1bD-3tm9A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubc | HEMOGLOBIN-LIKEFLAVOPROTEIN (Methylacidiphiluminfernorum) |
PF00042(Globin) | 5 | ILE A 24PHE A 28GLN A 50LEU A 99TYR A 123 | NoneNoneHEM A 201 ( 3.3A)NoneHEM A 201 (-4.4A) | 0.79A | 4g1bD-3ubcA:19.1 | 4g1bD-3ubcA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubc | HEMOGLOBIN-LIKEFLAVOPROTEIN (Methylacidiphiluminfernorum) |
PF00042(Globin) | 5 | ILE A 24PHE A 28PHE A 43LEU A 99TYR A 123 | NoneNoneHEM A 201 (-3.8A)NoneHEM A 201 (-4.4A) | 0.69A | 4g1bD-3ubcA:19.1 | 4g1bD-3ubcA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubc | HEMOGLOBIN-LIKEFLAVOPROTEIN (Methylacidiphiluminfernorum) |
PF00042(Globin) | 5 | ILE A 24PHE A 28TYR A 29GLN A 50TYR A 123 | NoneNoneNoneHEM A 201 ( 3.3A)HEM A 201 (-4.4A) | 0.89A | 4g1bD-3ubcA:19.1 | 4g1bD-3ubcA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ubc | HEMOGLOBIN-LIKEFLAVOPROTEIN (Methylacidiphiluminfernorum) |
PF00042(Globin) | 5 | ILE A 24PHE A 28TYR A 29PHE A 43TYR A 123 | NoneNoneNoneHEM A 201 (-3.8A)HEM A 201 (-4.4A) | 0.62A | 4g1bD-3ubcA:19.1 | 4g1bD-3ubcA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bru | ATP-DEPENDENT RNAHELICASE DHH1 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ILE A 413GLN A 260LEU A 382VAL A 354ILE A 288 | None | 1.01A | 4g1bD-4bruA:2.7 | 4g1bD-4bruA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ep5 | CROSSOVER JUNCTIONENDODEOXYRIBONUCLEASE RUVC (Thermusthermophilus) |
PF02075(RuvC) | 6 | THR A 153PHE A 156TYR A 157GLN A 112LEU A 114LEU A 26 | None | 1.47A | 4g1bD-4ep5A:undetectable | 4g1bD-4ep5A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fsf | PENICILLIN-BINDINGPROTEIN 3 (Pseudomonasaeruginosa) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | ILE A 114LEU A 89VAL A 142LEU A 125ILE A 138 | None | 1.04A | 4g1bD-4fsfA:undetectable | 4g1bD-4fsfA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gmf | YERSINIABACTINBIOSYNTHETIC PROTEINYBTU (Yersiniaenterocolitica) |
PF01408(GFO_IDH_MocA) | 5 | ILE A 333TYR A 165LEU A 329THR A 179VAL A 182 | None | 1.04A | 4g1bD-4gmfA:2.0 | 4g1bD-4gmfA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyj | RHODOPSIN (Exiguobacteriumsibiricum) |
PF01036(Bac_rhodopsin) | 5 | ILE A 187LEU A 161THR A 163VAL A 165LEU A 115 | None | 1.15A | 4g1bD-4hyjA:2.5 | 4g1bD-4hyjA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iv6 | ACYL-COADEHYDROGENASE FADE3 (Mycolicibacteriumsmegmatis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ILE A 182TYR A 145THR A 100LEU A 184TYR A 107 | None | 1.12A | 4g1bD-4iv6A:undetectable | 4g1bD-4iv6A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jpk | GERMLINE-TARGETINGHIV-1 GP120ENGINEERED OUTERDOMAIN, EOD-GT6 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 5 | ILE A 19THR A 20PHE A 63LEU A 91LEU A 22 | None | 1.02A | 4g1bD-4jpkA:undetectable | 4g1bD-4jpkA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k6j | WINGS APART-LIKEPROTEIN HOMOLOG (Homo sapiens) |
PF07814(WAPL) | 5 | ILE A 658LEU A 662THR A 706VAL A 703LEU A 681 | None | 1.07A | 4g1bD-4k6jA:2.2 | 4g1bD-4k6jA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9a | PUTATIVEUNCHARACTERIZEDPROTEIN SMU.1393C (Streptococcusmutans) |
no annotation | 5 | ILE A 216PHE A 121TYR A 235LEU A 97ILE A 83 | None | 1.12A | 4g1bD-4l9aA:2.8 | 4g1bD-4l9aA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lej | VICILIN (Pinuskoraiensis) |
PF00190(Cupin_1) | 5 | THR A 285PHE A 304LEU A 270VAL A 155LEU A 394 | None | 1.10A | 4g1bD-4lejA:undetectable | 4g1bD-4lejA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lh7 | DNA LIGASE (Enterococcusfaecalis) |
PF01653(DNA_ligase_aden) | 5 | ILE A 126LEU A 154THR A 156VAL A 157LEU A 209 | None | 1.03A | 4g1bD-4lh7A:undetectable | 4g1bD-4lh7A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ncn | EUKARYOTICTRANSLATIONINITIATION FACTOR5B-LIKE PROTEIN (Chaetomiumthermophilum) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2) | 5 | ILE A 780GLN A 749LEU A 839VAL A 767LEU A 774 | None | 1.07A | 4g1bD-4ncnA:2.3 | 4g1bD-4ncnA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4neg | TRYPTOPHAN SYNTHASEBETA CHAIN (Bacillusanthracis) |
PF00291(PALP) | 5 | ILE A 349THR A 344GLN A 341LEU A 343VAL A 359 | None | 1.13A | 4g1bD-4negA:2.7 | 4g1bD-4negA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6z | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumfalciparum) |
PF00464(SHMT) | 5 | ILE A 257PHE A 269THR A 232LEU A 112ILE A 179 | None | 1.02A | 4g1bD-4o6zA:undetectable | 4g1bD-4o6zA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqz | PUTATIVEOXIDOREDUCTASE YFJR (Streptomycesaurantiacus) |
PF03446(NAD_binding_2) | 6 | ILE A 63TYR A 26GLN A 3LEU A 61VAL A 87LEU A 148 | None | 1.37A | 4g1bD-4oqzA:4.6 | 4g1bD-4oqzA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9d | BENZOYLFORMATEDECARBOXYLASE (Mycolicibacteriumsmegmatis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | THR A 11TYR A 12PHE A 38THR A 98LEU A 20 | None | 0.95A | 4g1bD-4q9dA:3.8 | 4g1bD-4q9dA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qhx | UNCHARACTERIZEDPROTEIN (Bacteroidescaccae) |
PF11958(DUF3472)PF16871(DUF5077) | 5 | ILE A 132LEU A 119VAL A 83LEU A 135ILE A 107 | None | 0.91A | 4g1bD-4qhxA:undetectable | 4g1bD-4qhxA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r04 | TOXIN A (Clostridioidesdifficile) |
PF11713(Peptidase_C80)PF12918(TcdB_N)PF12919(TcdA_TcdB)PF12920(TcdA_TcdB_pore) | 5 | ILE A1538TYR A1565LEU A1555VAL A1552LEU A1586 | None | 1.13A | 4g1bD-4r04A:2.6 | 4g1bD-4r04A:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcd | BETA-SECRETASE 1 (Homo sapiens) |
PF00026(Asp) | 5 | ILE A 118GLN A 73THR A 231TYR A 198ILE A 226 | 3LL A 501 (-4.6A)NoneNoneNoneNone | 1.08A | 4g1bD-4rcdA:undetectable | 4g1bD-4rcdA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tmz | EIF5B (Chaetomiumthermophilum) |
no annotation | 5 | ILE B 780GLN B 749LEU B 839VAL B 767LEU B 774 | None | 1.14A | 4g1bD-4tmzB:2.6 | 4g1bD-4tmzB:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tmz | EIF5B (Chaetomiumthermophilum) |
no annotation | 5 | ILE B 780LEU B 839THR B 751VAL B 767LEU B 774 | None | 1.15A | 4g1bD-4tmzB:2.6 | 4g1bD-4tmzB:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d1v | GLOBIN (Chloroflexusaurantiacus) |
PF01152(Bac_globin) | 5 | ILE A 19PHE A 23TYR A 24PHE A 37LEU A 52 | NoneNoneNoneHEM A 201 (-3.5A)None | 0.85A | 4g1bD-5d1vA:6.5 | 4g1bD-5d1vA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dni | PUTATIVEL(+)-TARTRATEDEHYDRATASE SUBUNITBETA (Methanocaldococcusjannaschii) |
PF05683(Fumerase_C) | 5 | ILE A 57TYR A 59LEU A 24LEU A 123ILE A 21 | None | 1.06A | 4g1bD-5dniA:undetectable | 4g1bD-5dniA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ghe | PESTICIDAL CRYSTALPROTEIN CRY6AA (Bacillusthuringiensis) |
no annotation | 5 | ILE A 76GLN A 63LEU A 64LEU A 83ILE A 307 | None | 1.15A | 4g1bD-5gheA:undetectable | 4g1bD-5gheA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5d | INNER MEMBRANEPROTEIN YEJM (Salmonellaenterica) |
PF00884(Sulfatase)PF11893(DUF3413) | 5 | TYR A 512GLN A 500LEU A 503LEU A 330ILE A 446 | None | 1.01A | 4g1bD-5i5dA:undetectable | 4g1bD-5i5dA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9x | ADENYLATION DOMAIN (Streptomycessp.) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | PHE A 261LEU A 254VAL A 246LEU A 264ILE A 273 | None | 0.89A | 4g1bD-5n9xA:3.1 | 4g1bD-5n9xA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u81 | ACID CERAMIDASEISOFORM B (Heterocephalusglaber) |
no annotation | 5 | ILE A 52LEU A 189THR A 202VAL A 187TYR A 207 | None | 1.11A | 4g1bD-5u81A:undetectable | 4g1bD-5u81A:11.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uf8 | POTENTIALADP-RIBOSYLATIONFACTOR (Candidaalbicans) |
PF00025(Arf) | 5 | ILE A 148PHE A 82LEU A 121VAL A 123LEU A 107 | None | 1.12A | 4g1bD-5uf8A:3.8 | 4g1bD-5uf8A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v5g | UBIQUITIN VARIANTCC.4 (syntheticconstruct) |
PF00240(ubiquitin) | 5 | PHE B 45GLN B 62LEU B 56VAL B 17LEU B 67 | NoneEDO B 102 (-3.7A)NoneNoneNone | 1.14A | 4g1bD-5v5gB:undetectable | 4g1bD-5v5gB:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vem | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 5 (Homo sapiens) |
PF01663(Phosphodiest) | 5 | ILE A 235TYR A 53LEU A 233LEU A 218ILE A 171 | None | 0.99A | 4g1bD-5vemA:undetectable | 4g1bD-5vemA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vha | DEAH(ASP-GLU-ALA-HIS)BOX POLYPEPTIDE 36 (Bos taurus) |
no annotation | 5 | ILE A 317LEU A 348THR A 350VAL A 352LEU A 321 | None | 1.03A | 4g1bD-5vhaA:2.7 | 4g1bD-5vhaA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmr | SERINEHYDROXYMETHYLTRANSFERASE (Plasmodiumvivax) |
no annotation | 5 | ILE A 257PHE A 269THR A 232LEU A 112ILE A 179 | None | 0.97A | 4g1bD-5xmrA:undetectable | 4g1bD-5xmrA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y5w | SPINDLIN-1 (Homo sapiens) |
no annotation | 5 | ILE A 123THR A 131LEU A 182TYR A 185ILE A 192 | None | 1.14A | 4g1bD-5y5wA:undetectable | 4g1bD-5y5wA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydj | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | ILE A 478THR A 480TYR A 581LEU A 384VAL A 366 | None | 0.95A | 4g1bD-5ydjA:undetectable | 4g1bD-5ydjA:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysm | CYTOCHROME P450 (Amycolatopsismediterranei) |
no annotation | 5 | ILE A 307LEU A 69VAL A 68LEU A 357TYR A 62 | HEM A 501 (-4.4A)NoneNoneNoneNone | 1.08A | 4g1bD-5ysmA:undetectable | 4g1bD-5ysmA:9.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6arx | ACETYLCHOLINESTERASE (Anophelesgambiae) |
no annotation | 5 | ILE A 478THR A 480TYR A 581LEU A 384VAL A 366 | None | 1.03A | 4g1bD-6arxA:undetectable | 4g1bD-6arxA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b23 | MAJOR HEAD PROTEIN (Staphylococcusvirus 80alpha) |
no annotation | 5 | ILE A 47THR A 44LEU A 39THR A 38LEU A 291 | None | 1.13A | 4g1bD-6b23A:undetectable | 4g1bD-6b23A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bb9 | 4-AMINO-4-DEOXYCHORISMATE LYASE (Salmonellaenterica) |
no annotation | 5 | ILE A 83GLN A 44LEU A 46LEU A 63ILE A 36 | None | 1.14A | 4g1bD-6bb9A:undetectable | 4g1bD-6bb9A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g43 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 5 | ILE A 103LEU A 228VAL A 226LEU A 71ILE A 41 | None | 0.98A | 4g1bD-6g43A:undetectable | 4g1bD-6g43A:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g45 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 5 | ILE A 103LEU A 228VAL A 226LEU A 71ILE A 41 | None | 0.95A | 4g1bD-6g45A:undetectable | 4g1bD-6g45A:12.12 |