SIMILAR PATTERNS OF AMINO ACIDS FOR 4G1B_D_ECND403

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6m DNA TOPOISOMERASE
III


(Escherichia
coli)
PF01131
(Topoisom_bac)
PF01751
(Toprim)
5 ILE A 351
GLN A 409
LEU A 411
VAL A 364
ILE A 368
None
1.12A 4g1bD-1d6mA:
3.3
4g1bD-1d6mA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dly HEMOGLOBIN

(Chlamydomonas
moewusii)
PF01152
(Bac_globin)
5 PHE A  19
TYR A  20
PHE A  33
LEU A  49
LEU A  87
None
CYN  A 122 (-4.3A)
HEM  A 144 ( 4.4A)
None
None
1.15A 4g1bD-1dlyA:
10.0
4g1bD-1dlyA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0r THERMOSOME

(Thermoplasma
acidophilum)
PF00118
(Cpn60_TCP1)
5 ILE B 334
GLN B 292
LEU B 240
VAL B 289
LEU B 244
None
1.15A 4g1bD-1e0rB:
undetectable
4g1bD-1e0rB:
17.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gvh FLAVOHEMOPROTEIN

(Escherichia
coli)
PF00042
(Globin)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
6 THR A  25
PHE A  28
TYR A  29
PHE A  43
LEU A 102
TYR A 124
None
None
None
HEM  A1398 (-3.9A)
None
HEM  A1398 ( 4.9A)
0.64A 4g1bD-1gvhA:
44.0
4g1bD-1gvhA:
36.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvz KALLIKREIN-1E2

(Equus caballus)
PF00089
(Trypsin)
5 ILE A  66
GLN A 110
LEU A 108
LEU A  68
ILE A 114
None
1.01A 4g1bD-1gvzA:
undetectable
4g1bD-1gvzA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg4 ULTRASPIRACLE

(Drosophila
melanogaster)
PF00104
(Hormone_recep)
5 ILE A 481
THR A 482
PHE A 491
LEU A 476
ILE A 323
None
None
None
LPP  A   1 (-4.2A)
None
0.99A 4g1bD-1hg4A:
undetectable
4g1bD-1hg4A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkf NK CELL ACTIVATING
RECEPTOR


(Homo sapiens)
PF07686
(V-set)
5 ILE A  65
THR A  64
PHE A  63
VAL A  20
TYR A  89
None
1.13A 4g1bD-1hkfA:
undetectable
4g1bD-1hkfA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl7 MONOMER HEMOGLOBIN
COMPONENT III


(Glycera
dibranchiata)
PF00042
(Globin)
5 PHE A  45
LEU A  63
LEU A 110
TYR A 134
ILE A 137
HEM  A 148 (-3.7A)
None
None
None
None
0.64A 4g1bD-1jl7A:
16.7
4g1bD-1jl7A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE


(Escherichia
coli)
PF04055
(Radical_SAM)
PF06969
(HemN_C)
5 PHE A 284
GLN A   4
LEU A 277
TYR A 212
ILE A 269
None
1.10A 4g1bD-1oltA:
undetectable
4g1bD-1oltA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9h PROBABLE GTPASE ENGC

(Bacillus
subtilis)
PF03193
(RsgA_GTPase)
PF16745
(RsgA_N)
5 THR A 241
PHE A 242
PHE A 287
TYR A 137
ILE A 113
None
1.11A 4g1bD-1t9hA:
4.6
4g1bD-1t9hA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdu TRAS1 ORF2P

(Bombyx mori)
PF14529
(Exo_endo_phos_2)
5 ILE A  88
TYR A 125
LEU A  53
VAL A  25
ILE A 223
None
1.10A 4g1bD-1wduA:
undetectable
4g1bD-1wduA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhb POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 1


(Mus musculus)
PF00535
(Glycos_transf_2)
PF00652
(Ricin_B_lectin)
5 ILE A 434
GLN A 441
LEU A 443
VAL A 454
LEU A 524
None
0.95A 4g1bD-1xhbA:
2.5
4g1bD-1xhbA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eh0 KINESIN-LIKE PROTEIN
KIF1B


(Homo sapiens)
PF00498
(FHA)
PF16183
(Kinesin_assoc)
5 ILE A 101
PHE A 111
GLN A  94
LEU A  74
ILE A  32
None
1.03A 4g1bD-2eh0A:
undetectable
4g1bD-2eh0A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fm8 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAK


(Salmonella
enterica)
PF03519
(Invas_SpaK)
5 ILE A  54
LEU A 119
VAL A  10
LEU A  35
ILE A  24
None
1.15A 4g1bD-2fm8A:
undetectable
4g1bD-2fm8A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fus FUMARASE C

(Escherichia
coli)
PF00206
(Lyase_1)
PF10415
(FumaraseC_C)
5 ILE A 215
GLN A 163
LEU A 164
LEU A 284
ILE A 291
None
1.14A 4g1bD-2fusA:
undetectable
4g1bD-2fusA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i14 NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE


(Pyrococcus
furiosus)
PF01729
(QRPTase_C)
PF02749
(QRPTase_N)
5 ILE A 265
PHE A 266
PHE A 134
LEU A 234
VAL A 208
None
None
PCP  A 392 (-4.2A)
None
None
1.07A 4g1bD-2i14A:
undetectable
4g1bD-2i14A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icu HYPOTHETICAL PROTEIN
YEDK


(Escherichia
coli)
PF02586
(SRAP)
5 ILE A 154
PHE A 124
VAL A  51
TYR A  21
ILE A  40
None
1.10A 4g1bD-2icuA:
undetectable
4g1bD-2icuA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixm SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
REGULATORY SUBUNIT
B'


(Homo sapiens)
PF03095
(PTPA)
5 ILE A 180
PHE A 185
LEU A  55
TYR A  48
ILE A  49
None
1.01A 4g1bD-2ixmA:
undetectable
4g1bD-2ixmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lvw ACETOLACTATE
SYNTHASE ISOZYME 1
SMALL SUBUNIT


(Escherichia
coli)
PF01842
(ACT)
5 ILE A  71
GLN A  81
LEU A  15
THR A  16
VAL A  17
None
1.15A 4g1bD-2lvwA:
undetectable
4g1bD-2lvwA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2npn PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN


(Corynebacterium
diphtheriae)
PF00590
(TP_methylase)
5 ILE A 121
THR A 118
LEU A  34
VAL A  63
LEU A  90
None
1.15A 4g1bD-2npnA:
2.1
4g1bD-2npnA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1o PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE


(Cryptosporidium
parvum)
PF00348
(polyprenyl_synt)
6 ILE A 169
PHE A 161
LEU A 100
VAL A 103
LEU A 157
ILE A  38
None
1.32A 4g1bD-2o1oA:
undetectable
4g1bD-2o1oA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odl ADHESIN

(Haemophilus
influenzae)
PF05860
(Haemagg_act)
5 ILE A 310
LEU A 301
VAL A 275
LEU A 286
ILE A 231
None
1.15A 4g1bD-2odlA:
undetectable
4g1bD-2odlA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt5 GLUTAMATE
RECEPTOR-INTERACTING
PROTEIN 1


(Rattus
norvegicus)
PF00595
(PDZ)
5 ILE A 101
GLN A  94
LEU A 130
VAL A 128
LEU A  66
None
1.09A 4g1bD-2qt5A:
undetectable
4g1bD-2qt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9y ALPHA-2-ANTIPLASMIN

(Mus musculus)
PF00079
(Serpin)
5 ILE A 133
PHE A 159
GLN A 126
LEU A 128
LEU A  84
None
1.02A 4g1bD-2r9yA:
undetectable
4g1bD-2r9yA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsm HEMAGGLUTININ-NEURAM
INIDASE


(Nipah
henipavirus)
PF00423
(HN)
5 ILE A 431
THR A 471
VAL A 469
LEU A 413
TYR A 363
None
1.14A 4g1bD-2vsmA:
undetectable
4g1bD-2vsmA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnk SPOROZOITE-SPECIFIC
SAG PROTEIN


(Toxoplasma
gondii)
PF04092
(SAG)
5 TYR A  39
LEU A  84
THR A  85
VAL A  86
LEU A  59
None
1.10A 4g1bD-2wnkA:
undetectable
4g1bD-2wnkA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN


(Campylobacter
jejuni)
PF00042
(Globin)
6 PHE A  27
TYR A  28
GLN A  52
LEU A 101
TYR A 123
ILE A 126
None
CYN  A 151 (-4.7A)
HEM  A 150 ( 3.6A)
None
None
HEM  A 150 ( 4.8A)
0.86A 4g1bD-2wy4A:
20.9
4g1bD-2wy4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN


(Campylobacter
jejuni)
PF00042
(Globin)
5 PHE A  27
TYR A  28
LEU A  23
LEU A 101
TYR A 123
None
CYN  A 151 (-4.7A)
None
None
None
1.12A 4g1bD-2wy4A:
20.9
4g1bD-2wy4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN


(Campylobacter
jejuni)
PF00042
(Globin)
6 PHE A  27
TYR A  28
PHE A  42
LEU A 101
TYR A 123
ILE A 126
None
CYN  A 151 (-4.7A)
HEM  A 150 ( 3.5A)
None
None
HEM  A 150 ( 4.8A)
0.78A 4g1bD-2wy4A:
20.9
4g1bD-2wy4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN


(Campylobacter
jejuni)
PF00042
(Globin)
5 THR A  24
PHE A  27
TYR A  28
GLN A  52
TYR A 123
None
None
CYN  A 151 (-4.7A)
HEM  A 150 ( 3.6A)
None
0.89A 4g1bD-2wy4A:
20.9
4g1bD-2wy4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy4 SINGLE DOMAIN
HAEMOGLOBIN


(Campylobacter
jejuni)
PF00042
(Globin)
5 THR A  24
PHE A  27
TYR A  28
PHE A  42
TYR A 123
None
None
CYN  A 151 (-4.7A)
HEM  A 150 ( 3.5A)
None
0.83A 4g1bD-2wy4A:
20.9
4g1bD-2wy4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh1 KYNURENINE/ALPHA-AMI
NOADIPATE
AMINOTRANSFERASE,
MITOCHONDRIAL


(Homo sapiens)
PF00155
(Aminotran_1_2)
5 ILE A 421
GLN A 415
LEU A 417
LEU A 341
ILE A 333
None
1.07A 4g1bD-2xh1A:
undetectable
4g1bD-2xh1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ysk HYPOTHETICAL PROTEIN
TTHA1432


(Thermus
thermophilus)
PF10025
(DUF2267)
5 ILE A  23
PHE A  89
LEU A  39
VAL A  66
LEU A 118
None
1.14A 4g1bD-2yskA:
undetectable
4g1bD-2yskA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqg ZYMOGEN GRANULE
PROTEIN 16 HOMOLOG B


(Homo sapiens)
PF01419
(Jacalin)
5 ILE A 179
GLN A 127
LEU A 130
VAL A  86
TYR A 144
None
1.14A 4g1bD-3aqgA:
undetectable
4g1bD-3aqgA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1x HEPATOCYTE GROWTH
FACTOR RECEPTOR


(Homo sapiens)
PF07714
(Pkinase_Tyr)
5 THR A1126
GLN A1123
LEU A1125
LEU A1058
ILE A1053
None
1.13A 4g1bD-3c1xA:
undetectable
4g1bD-3c1xA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwx PROTEIN CAGD

(Helicobacter
pylori)
PF16567
(CagD)
5 ILE A 166
LEU A 122
LEU A 137
TYR A 138
ILE A  62
None
1.15A 4g1bD-3cwxA:
undetectable
4g1bD-3cwxA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dv9 BETA-PHOSPHOGLUCOMUT
ASE


(Bacteroides
vulgatus)
PF13419
(HAD_2)
5 PHE A 230
PHE A  25
LEU A 222
LEU A 237
ILE A  18
None
1.13A 4g1bD-3dv9A:
5.1
4g1bD-3dv9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3et5 OUTER MEMBRANE
PROTEIN P4, NADP
PHOSPHATASE


(Haemophilus
influenzae)
PF03767
(Acid_phosphat_B)
5 ILE A 214
PHE A 213
LEU A 177
VAL A  61
ILE A 168
None
1.03A 4g1bD-3et5A:
3.4
4g1bD-3et5A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN


(Plexaura
homomalla)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 ILE A 649
LEU A 645
VAL A 635
LEU A 624
ILE A 726
None
1.14A 4g1bD-3fg4A:
2.2
4g1bD-3fg4A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7n NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae)
PF11715
(Nup160)
6 TYR A 701
PHE A 692
LEU A 679
VAL A 678
LEU A 616
TYR A  14
None
1.48A 4g1bD-3h7nA:
undetectable
4g1bD-3h7nA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42


(Schizosaccharomyces
pombe)
PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
5 ILE A1771
LEU A1560
THR A1559
LEU A1597
ILE A1590
None
1.14A 4g1bD-3jb9A:
undetectable
4g1bD-3jb9A:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9x PHOSPHOTRANSFERASE

(Plasmodium
berghei)
PF00069
(Pkinase)
6 ILE A 241
THR A 238
PHE A 242
LEU A 138
VAL A 168
LEU A 245
None
1.17A 4g1bD-3n9xA:
undetectable
4g1bD-3n9xA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nie MAP2 KINASE

(Plasmodium
falciparum)
PF00069
(Pkinase)
6 ILE A 246
THR A 243
PHE A 247
LEU A 140
VAL A 170
LEU A 250
None
1.18A 4g1bD-3nieA:
undetectable
4g1bD-3nieA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o90 NICOTINAMIDASE

(Streptococcus
pneumoniae)
PF00857
(Isochorismatase)
5 ILE A  52
THR A  51
PHE A  50
VAL A 131
ILE A  30
None
1.13A 4g1bD-3o90A:
6.7
4g1bD-3o90A:
19.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator)
no annotation 7 ILE B  24
PHE B  28
TYR B  29
PHE B  43
LEU B  57
LEU B 102
TYR B 126
ECN  B 411 (-3.5A)
ECN  B 411 (-4.0A)
None
HEM  B 404 ( 3.8A)
ECN  B 411 (-4.1A)
ECN  B 411 (-3.2A)
HEM  B 404 ( 3.9A)
0.90A 4g1bD-3ozvB:
46.8
4g1bD-3ozvB:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator)
no annotation 6 ILE B  24
PHE B  28
TYR B  29
PHE B  43
LEU B  57
VAL B  61
ECN  B 411 (-3.5A)
ECN  B 411 (-4.0A)
None
HEM  B 404 ( 3.8A)
ECN  B 411 (-4.1A)
DGG  B 406 ( 4.8A)
0.90A 4g1bD-3ozvB:
46.8
4g1bD-3ozvB:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ozv FLAVOHEMOGLOBIN

(Cupriavidus
necator)
no annotation 5 PHE B  28
PHE B  43
GLN B  53
LEU B 102
TYR B 126
ECN  B 411 (-4.0A)
HEM  B 404 ( 3.8A)
HEM  B 404 (-3.9A)
ECN  B 411 (-3.2A)
HEM  B 404 ( 3.9A)
1.14A 4g1bD-3ozvB:
46.8
4g1bD-3ozvB:
37.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3phu RNA-DIRECTED RNA
POLYMERASE L


(Crimean-Congo
hemorrhagic
fever
orthonairovirus)
PF02338
(OTU)
5 ILE A  31
PHE A  29
LEU A 145
THR A 120
VAL A 121
None
0.96A 4g1bD-3phuA:
undetectable
4g1bD-3phuA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pse RNA POLYMERASE

(Crimean-Congo
hemorrhagic
fever
orthonairovirus)
PF02338
(OTU)
5 ILE A  31
PHE A  29
LEU A 145
THR A 120
VAL A 121
None
0.98A 4g1bD-3pseA:
undetectable
4g1bD-3pseA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdq 4-HYDROXYBUTYRATE
COA-TRANSFERASE


(Clostridium
aminobutyricum)
PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C)
6 ILE A 267
THR A 268
LEU A 288
VAL A 162
LEU A 270
TYR A 277
None
1.31A 4g1bD-3qdqA:
3.2
4g1bD-3qdqA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qml NUCLEOTIDE EXCHANGE
FACTOR SIL1


(Saccharomyces
cerevisiae)
PF16782
(SIL1)
5 ILE C 244
LEU C 248
VAL C 286
TYR C 264
ILE C 293
None
1.06A 4g1bD-3qmlC:
undetectable
4g1bD-3qmlC:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2s PUTATIVE
PYRAZINAMIDASE/NICOT
INAMIDASE


(Streptococcus
mutans)
PF00857
(Isochorismatase)
5 ILE A  52
THR A  51
PHE A  50
VAL A 131
ILE A  30
None
1.10A 4g1bD-3s2sA:
6.7
4g1bD-3s2sA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tm9 BACTERIAL HEMOGLOBIN

(Vitreoscilla
stercoraria)
PF00042
(Globin)
7 ILE A  24
THR A  25
PHE A  28
PHE A  43
LEU A 102
TYR A 126
ILE A 129
None
None
None
HEM  A 201 (-3.1A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
0.82A 4g1bD-3tm9A:
19.9
4g1bD-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tm9 BACTERIAL HEMOGLOBIN

(Vitreoscilla
stercoraria)
PF00042
(Globin)
7 ILE A  24
THR A  25
PHE A  43
THR A  60
LEU A 102
TYR A 126
ILE A 129
None
None
HEM  A 201 (-3.1A)
HEM  A 201 (-2.5A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
1.06A 4g1bD-3tm9A:
19.9
4g1bD-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubc HEMOGLOBIN-LIKE
FLAVOPROTEIN


(Methylacidiphilum
infernorum)
PF00042
(Globin)
5 ILE A  24
PHE A  28
GLN A  50
LEU A  99
TYR A 123
None
None
HEM  A 201 ( 3.3A)
None
HEM  A 201 (-4.4A)
0.79A 4g1bD-3ubcA:
19.1
4g1bD-3ubcA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubc HEMOGLOBIN-LIKE
FLAVOPROTEIN


(Methylacidiphilum
infernorum)
PF00042
(Globin)
5 ILE A  24
PHE A  28
PHE A  43
LEU A  99
TYR A 123
None
None
HEM  A 201 (-3.8A)
None
HEM  A 201 (-4.4A)
0.69A 4g1bD-3ubcA:
19.1
4g1bD-3ubcA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubc HEMOGLOBIN-LIKE
FLAVOPROTEIN


(Methylacidiphilum
infernorum)
PF00042
(Globin)
5 ILE A  24
PHE A  28
TYR A  29
GLN A  50
TYR A 123
None
None
None
HEM  A 201 ( 3.3A)
HEM  A 201 (-4.4A)
0.89A 4g1bD-3ubcA:
19.1
4g1bD-3ubcA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubc HEMOGLOBIN-LIKE
FLAVOPROTEIN


(Methylacidiphilum
infernorum)
PF00042
(Globin)
5 ILE A  24
PHE A  28
TYR A  29
PHE A  43
TYR A 123
None
None
None
HEM  A 201 (-3.8A)
HEM  A 201 (-4.4A)
0.62A 4g1bD-3ubcA:
19.1
4g1bD-3ubcA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bru ATP-DEPENDENT RNA
HELICASE DHH1


(Saccharomyces
cerevisiae)
PF00270
(DEAD)
PF00271
(Helicase_C)
5 ILE A 413
GLN A 260
LEU A 382
VAL A 354
ILE A 288
None
1.01A 4g1bD-4bruA:
2.7
4g1bD-4bruA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep5 CROSSOVER JUNCTION
ENDODEOXYRIBONUCLEAS
E RUVC


(Thermus
thermophilus)
PF02075
(RuvC)
6 THR A 153
PHE A 156
TYR A 157
GLN A 112
LEU A 114
LEU A  26
None
1.47A 4g1bD-4ep5A:
undetectable
4g1bD-4ep5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fsf PENICILLIN-BINDING
PROTEIN 3


(Pseudomonas
aeruginosa)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
5 ILE A 114
LEU A  89
VAL A 142
LEU A 125
ILE A 138
None
1.04A 4g1bD-4fsfA:
undetectable
4g1bD-4fsfA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmf YERSINIABACTIN
BIOSYNTHETIC PROTEIN
YBTU


(Yersinia
enterocolitica)
PF01408
(GFO_IDH_MocA)
5 ILE A 333
TYR A 165
LEU A 329
THR A 179
VAL A 182
None
1.04A 4g1bD-4gmfA:
2.0
4g1bD-4gmfA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyj RHODOPSIN

(Exiguobacterium
sibiricum)
PF01036
(Bac_rhodopsin)
5 ILE A 187
LEU A 161
THR A 163
VAL A 165
LEU A 115
None
1.15A 4g1bD-4hyjA:
2.5
4g1bD-4hyjA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv6 ACYL-COA
DEHYDROGENASE FADE3


(Mycolicibacterium
smegmatis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
5 ILE A 182
TYR A 145
THR A 100
LEU A 184
TYR A 107
None
1.12A 4g1bD-4iv6A:
undetectable
4g1bD-4iv6A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jpk GERMLINE-TARGETING
HIV-1 GP120
ENGINEERED OUTER
DOMAIN, EOD-GT6


(Human
immunodeficiency
virus 1)
PF00516
(GP120)
5 ILE A  19
THR A  20
PHE A  63
LEU A  91
LEU A  22
None
1.02A 4g1bD-4jpkA:
undetectable
4g1bD-4jpkA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6j WINGS APART-LIKE
PROTEIN HOMOLOG


(Homo sapiens)
PF07814
(WAPL)
5 ILE A 658
LEU A 662
THR A 706
VAL A 703
LEU A 681
None
1.07A 4g1bD-4k6jA:
2.2
4g1bD-4k6jA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C


(Streptococcus
mutans)
no annotation 5 ILE A 216
PHE A 121
TYR A 235
LEU A  97
ILE A  83
None
1.12A 4g1bD-4l9aA:
2.8
4g1bD-4l9aA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lej VICILIN

(Pinus
koraiensis)
PF00190
(Cupin_1)
5 THR A 285
PHE A 304
LEU A 270
VAL A 155
LEU A 394
None
1.10A 4g1bD-4lejA:
undetectable
4g1bD-4lejA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lh7 DNA LIGASE

(Enterococcus
faecalis)
PF01653
(DNA_ligase_aden)
5 ILE A 126
LEU A 154
THR A 156
VAL A 157
LEU A 209
None
1.03A 4g1bD-4lh7A:
undetectable
4g1bD-4lh7A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncn EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN


(Chaetomium
thermophilum)
PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
5 ILE A 780
GLN A 749
LEU A 839
VAL A 767
LEU A 774
None
1.07A 4g1bD-4ncnA:
2.3
4g1bD-4ncnA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4neg TRYPTOPHAN SYNTHASE
BETA CHAIN


(Bacillus
anthracis)
PF00291
(PALP)
5 ILE A 349
THR A 344
GLN A 341
LEU A 343
VAL A 359
None
1.13A 4g1bD-4negA:
2.7
4g1bD-4negA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6z SERINE
HYDROXYMETHYLTRANSFE
RASE


(Plasmodium
falciparum)
PF00464
(SHMT)
5 ILE A 257
PHE A 269
THR A 232
LEU A 112
ILE A 179
None
1.02A 4g1bD-4o6zA:
undetectable
4g1bD-4o6zA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqz PUTATIVE
OXIDOREDUCTASE YFJR


(Streptomyces
aurantiacus)
PF03446
(NAD_binding_2)
6 ILE A  63
TYR A  26
GLN A   3
LEU A  61
VAL A  87
LEU A 148
None
1.37A 4g1bD-4oqzA:
4.6
4g1bD-4oqzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9d BENZOYLFORMATE
DECARBOXYLASE


(Mycolicibacterium
smegmatis)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
5 THR A  11
TYR A  12
PHE A  38
THR A  98
LEU A  20
None
0.95A 4g1bD-4q9dA:
3.8
4g1bD-4q9dA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhx UNCHARACTERIZED
PROTEIN


(Bacteroides
caccae)
PF11958
(DUF3472)
PF16871
(DUF5077)
5 ILE A 132
LEU A 119
VAL A  83
LEU A 135
ILE A 107
None
0.91A 4g1bD-4qhxA:
undetectable
4g1bD-4qhxA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile)
PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore)
5 ILE A1538
TYR A1565
LEU A1555
VAL A1552
LEU A1586
None
1.13A 4g1bD-4r04A:
2.6
4g1bD-4r04A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcd BETA-SECRETASE 1

(Homo sapiens)
PF00026
(Asp)
5 ILE A 118
GLN A  73
THR A 231
TYR A 198
ILE A 226
3LL  A 501 (-4.6A)
None
None
None
None
1.08A 4g1bD-4rcdA:
undetectable
4g1bD-4rcdA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmz EIF5B

(Chaetomium
thermophilum)
no annotation 5 ILE B 780
GLN B 749
LEU B 839
VAL B 767
LEU B 774
None
1.14A 4g1bD-4tmzB:
2.6
4g1bD-4tmzB:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmz EIF5B

(Chaetomium
thermophilum)
no annotation 5 ILE B 780
LEU B 839
THR B 751
VAL B 767
LEU B 774
None
1.15A 4g1bD-4tmzB:
2.6
4g1bD-4tmzB:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1v GLOBIN

(Chloroflexus
aurantiacus)
PF01152
(Bac_globin)
5 ILE A  19
PHE A  23
TYR A  24
PHE A  37
LEU A  52
None
None
None
HEM  A 201 (-3.5A)
None
0.85A 4g1bD-5d1vA:
6.5
4g1bD-5d1vA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dni PUTATIVE
L(+)-TARTRATE
DEHYDRATASE SUBUNIT
BETA


(Methanocaldococcus
jannaschii)
PF05683
(Fumerase_C)
5 ILE A  57
TYR A  59
LEU A  24
LEU A 123
ILE A  21
None
1.06A 4g1bD-5dniA:
undetectable
4g1bD-5dniA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghe PESTICIDAL CRYSTAL
PROTEIN CRY6AA


(Bacillus
thuringiensis)
no annotation 5 ILE A  76
GLN A  63
LEU A  64
LEU A  83
ILE A 307
None
1.15A 4g1bD-5gheA:
undetectable
4g1bD-5gheA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i5d INNER MEMBRANE
PROTEIN YEJM


(Salmonella
enterica)
PF00884
(Sulfatase)
PF11893
(DUF3413)
5 TYR A 512
GLN A 500
LEU A 503
LEU A 330
ILE A 446
None
1.01A 4g1bD-5i5dA:
undetectable
4g1bD-5i5dA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9x ADENYLATION DOMAIN

(Streptomyces
sp.)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
5 PHE A 261
LEU A 254
VAL A 246
LEU A 264
ILE A 273
None
0.89A 4g1bD-5n9xA:
3.1
4g1bD-5n9xA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B


(Heterocephalus
glaber)
no annotation 5 ILE A  52
LEU A 189
THR A 202
VAL A 187
TYR A 207
None
1.11A 4g1bD-5u81A:
undetectable
4g1bD-5u81A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR


(Candida
albicans)
PF00025
(Arf)
5 ILE A 148
PHE A  82
LEU A 121
VAL A 123
LEU A 107
None
1.12A 4g1bD-5uf8A:
3.8
4g1bD-5uf8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v5g UBIQUITIN VARIANT
CC.4


(synthetic
construct)
PF00240
(ubiquitin)
5 PHE B  45
GLN B  62
LEU B  56
VAL B  17
LEU B  67
None
EDO  B 102 (-3.7A)
None
None
None
1.14A 4g1bD-5v5gB:
undetectable
4g1bD-5v5gB:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5


(Homo sapiens)
PF01663
(Phosphodiest)
5 ILE A 235
TYR A  53
LEU A 233
LEU A 218
ILE A 171
None
0.99A 4g1bD-5vemA:
undetectable
4g1bD-5vemA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vha DEAH
(ASP-GLU-ALA-HIS)
BOX POLYPEPTIDE 36


(Bos taurus)
no annotation 5 ILE A 317
LEU A 348
THR A 350
VAL A 352
LEU A 321
None
1.03A 4g1bD-5vhaA:
2.7
4g1bD-5vhaA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmr SERINE
HYDROXYMETHYLTRANSFE
RASE


(Plasmodium
vivax)
no annotation 5 ILE A 257
PHE A 269
THR A 232
LEU A 112
ILE A 179
None
0.97A 4g1bD-5xmrA:
undetectable
4g1bD-5xmrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y5w SPINDLIN-1

(Homo sapiens)
no annotation 5 ILE A 123
THR A 131
LEU A 182
TYR A 185
ILE A 192
None
1.14A 4g1bD-5y5wA:
undetectable
4g1bD-5y5wA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydj ACETYLCHOLINESTERASE

(Anopheles
gambiae)
no annotation 5 ILE A 478
THR A 480
TYR A 581
LEU A 384
VAL A 366
None
0.95A 4g1bD-5ydjA:
undetectable
4g1bD-5ydjA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ysm CYTOCHROME P450

(Amycolatopsis
mediterranei)
no annotation 5 ILE A 307
LEU A  69
VAL A  68
LEU A 357
TYR A  62
HEM  A 501 (-4.4A)
None
None
None
None
1.08A 4g1bD-5ysmA:
undetectable
4g1bD-5ysmA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6arx ACETYLCHOLINESTERASE

(Anopheles
gambiae)
no annotation 5 ILE A 478
THR A 480
TYR A 581
LEU A 384
VAL A 366
None
1.03A 4g1bD-6arxA:
undetectable
4g1bD-6arxA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b23 MAJOR HEAD PROTEIN

(Staphylococcus
virus 80alpha)
no annotation 5 ILE A  47
THR A  44
LEU A  39
THR A  38
LEU A 291
None
1.13A 4g1bD-6b23A:
undetectable
4g1bD-6b23A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE


(Salmonella
enterica)
no annotation 5 ILE A  83
GLN A  44
LEU A  46
LEU A  63
ILE A  36
None
1.14A 4g1bD-6bb9A:
undetectable
4g1bD-6bb9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g43 PUTATIVE MAJOR
CAPSID PROTEIN


(Cafeteriavirus-dependent
mavirus)
no annotation 5 ILE A 103
LEU A 228
VAL A 226
LEU A  71
ILE A  41
None
0.98A 4g1bD-6g43A:
undetectable
4g1bD-6g43A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g45 PUTATIVE MAJOR
CAPSID PROTEIN


(Cafeteriavirus-dependent
mavirus)
no annotation 5 ILE A 103
LEU A 228
VAL A 226
LEU A  71
ILE A  41
None
0.95A 4g1bD-6g45A:
undetectable
4g1bD-6g45A:
12.12