SIMILAR PATTERNS OF AMINO ACIDS FOR 4G19_D_ACTD305

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bm8 TRANSCRIPTION FACTOR
MBP1

(Saccharomyces
cerevisiae) 		PF04383
(KilA-N) 		4 ILE A  39
LEU A  40
LYS A  41
ASN A  35
 None
 1.19A 4g19D-1bm8A:
0.0		 4g19D-1bm8A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c1e CATALYTIC ANTIBODY
1E9 (HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE H  82
LEU H  80
LYS H  19
ASN H  82
 None
 1.36A 4g19D-1c1eH:
0.0		 4g19D-1c1eH:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kij DNA GYRASE SUBUNIT B

(Thermus
thermophilus) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 ILE A  58
LEU A 201
LYS A 202
ASN A  73
 None
 1.33A 4g19D-1kijA:
0.0		 4g19D-1kijA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mb1 MLU1-BOX BINDING
PROTEIN

(Saccharomyces
cerevisiae) 		PF04383
(KilA-N) 		4 ILE A  39
LEU A  40
LYS A  41
ASN A  35
 None
 1.30A 4g19D-1mb1A:
0.0		 4g19D-1mb1A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mk2 SMAD 3

(Homo sapiens) 		PF03166
(MH2) 		4 ILE A 341
LEU A 339
LYS A 340
ASN A 318
 None
 1.02A 4g19D-1mk2A:
0.0		 4g19D-1mk2A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ncb IGG2A-KAPPA NC41 FAB
(HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE H  82
LEU H  80
LYS H  19
ASN H  82
 None
 1.35A 4g19D-1ncbH:
0.0		 4g19D-1ncbH:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tyj CELLULOSOMAL
SCAFFOLDIN

(Pseudobacteroides
cellulosolvens) 		PF00963
(Cohesin) 		4 ILE A  23
LEU A  21
LYS A 113
ASN A  24
 None
 1.03A 4g19D-1tyjA:
0.0		 4g19D-1tyjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wba WINGED BEAN ALBUMIN
1

(Psophocarpus
tetragonolobus) 		PF00197
(Kunitz_legume) 		4 ILE A  59
LEU A  78
LYS A  79
ASN A  15
 None
 1.33A 4g19D-1wbaA:
undetectable		 4g19D-1wbaA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reu TYPE II RESTRICTION
ENZYME SAU3AI

(Staphylococcus
aureus) 		no annotation 4 ILE A 222
LEU A 218
LYS A 220
ASN A 223
 None
 1.32A 4g19D-2reuA:
0.0		 4g19D-2reuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vaw CELL DIVISION
PROTEIN FTSZ

(Pseudomonas
aeruginosa) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 ILE A 172
LEU A 169
LYS A 168
ASN A 247
 None
 1.05A 4g19D-2vawA:
undetectable		 4g19D-2vawA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus) 		PF00148
(Oxidored_nitro) 		4 ILE C 187
LEU C 164
LYS C 189
ASN C 183
 None
 1.42A 4g19D-2ynmC:
undetectable		 4g19D-2ynmC:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dby UNCHARACTERIZED
PROTEIN

(Bacillus cereus) 		PF11155
(DUF2935) 		4 ILE A  84
LEU A  81
LYS A  80
ASN A 102
 None
 1.35A 4g19D-3dbyA:
undetectable		 4g19D-3dbyA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8u FAB 106.3 HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE H  82
LEU H  80
LYS H  19
ASN H  82
 None
 1.40A 4g19D-3e8uH:
undetectable		 4g19D-3e8uH:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igo CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ILE A 282
LEU A 283
LYS A 284
ASN A 278
 None
 1.08A 4g19D-3igoA:
undetectable		 4g19D-3igoA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iy4 FRAGMENT OF
NEUTRALIZING
ANTIBODY 15 (HEAVY
CHAIN)

(Mus musculus) 		PF07686
(V-set) 		4 ILE B 188
LEU B 186
LYS B 124
ASN B 189
 None
 1.27A 4g19D-3iy4B:
undetectable		 4g19D-3iy4B:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9h PF-32 PROTEIN

(Borreliella
burgdorferi) 		PF13614
(AAA_31) 		4 ILE A  71
LEU A  72
LYS A  73
ASN A  67
 None
 0.96A 4g19D-3k9hA:
undetectable		 4g19D-3k9hA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgb DNA PRIMASE LARGE
SUBUNIT

(Saccharomyces
cerevisiae) 		PF04104
(DNA_primase_lrg) 		4 ILE A 365
LEU A 362
LYS A 363
ASN A 501
 None
 1.03A 4g19D-3lgbA:
undetectable		 4g19D-3lgbA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnl UPF0135 PROTEIN
SA1388

(Staphylococcus
aureus) 		PF01784
(NIF3) 		4 ILE A 328
LEU A 265
LYS A 262
ASN A 329
 None
 1.10A 4g19D-3lnlA:
undetectable		 4g19D-3lnlA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogr BETA-GALACTOSIDASE

(Trichoderma
reesei) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ILE A 976
LEU A 911
LYS A 910
ASN A 944
 None
 1.14A 4g19D-3ogrA:
undetectable		 4g19D-3ogrA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojd FAB V2D2

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE B  82
LEU B  80
LYS B  19
ASN B  82
 None
 1.48A 4g19D-3ojdB:
undetectable		 4g19D-3ojdB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 ILE A 856
LEU A 852
LYS A 855
ASN A 894
 None
 1.44A 4g19D-3s5kA:
undetectable		 4g19D-3s5kA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiq KOJIBIOSE
PHOSPHORYLASE

(Caldicellulosiruptor
saccharolyticus) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 ILE A 295
LEU A 714
LYS A 715
ASN A 304
 None
 1.03A 4g19D-3wiqA:
undetectable		 4g19D-3wiqA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a6o ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 ILE A1313
LEU A1255
LYS A1315
ASN A1258
 None
 1.35A 4g19D-4a6oA:
undetectable		 4g19D-4a6oA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyj PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3-LIKE PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ILE A 384
LEU A 381
LYS A 382
ASN A 313
 None
 1.19A 4g19D-4cyjA:
undetectable		 4g19D-4cyjA:
20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4g19 GLUTATHIONE
TRANSFERASE GTE1

(Phanerochaete
chrysosporium) 		PF13417
(GST_N_3) 		4 ILE A   5
LEU A  37
LYS A  38
ASN A  80
 None
ACT  A 304 (-4.2A)
None
ACT  A 304 ( 4.6A)
 0.57A 4g19D-4g19A:
43.7		 4g19D-4g19A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcm THIOREDOXIN
REDUCTASE

(Staphylococcus
aureus) 		PF07992
(Pyr_redox_2) 		4 ILE A 206
LEU A 203
LYS A 204
ASN A 207
 None
 1.49A 4g19D-4gcmA:
undetectable		 4g19D-4gcmA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lci ANTI CANINE CD28
ANTIBODY, 1C6, HEAVY
CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 ILE H  80
LEU H  78
LYS H  19
ASN H  81
 None
 1.40A 4g19D-4lciH:
undetectable		 4g19D-4lciH:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnf GLUTAMINE SYNTHETASE

(Bacillus
subtilis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ILE A 115
LEU A 116
LYS A 117
ASN A 111
 None
 1.33A 4g19D-4lnfA:
undetectable		 4g19D-4lnfA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lpl GLYCOSYL HYDROLASE,
FAMILY
31/FIBRONECTIN TYPE
III DOMAIN PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 ILE A1063
LEU A1015
LYS A1061
ASN A1045
 None
 1.15A 4g19D-4lplA:
undetectable		 4g19D-4lplA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgj CALCIUM-DEPENDENT
PROTEIN KINASE 4

(Plasmodium
falciparum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ILE A 278
LEU A 279
LYS A 280
ASN A 274
 None
 0.85A 4g19D-4rgjA:
undetectable		 4g19D-4rgjA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tz5 PUTATIVE SECRETED
PROTEIN

(Streptomyces
sp. SirexAA-E) 		no annotation 4 ILE A 344
LEU A 368
LYS A 369
ASN A 320
 None
 1.15A 4g19D-4tz5A:
undetectable		 4g19D-4tz5A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4urn DNA TOPOISOMERASE
IV, B SUBUNIT

(Staphylococcus
aureus) 		PF02518
(HATPase_c) 		4 ILE A  62
LEU A 204
LYS A 205
ASN A  77
 None
 1.42A 4g19D-4urnA:
undetectable		 4g19D-4urnA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ux5 TRANSCRIPTION FACTOR
MBP1

(Magnaporthe
oryzae) 		PF04383
(KilA-N) 		4 ILE A  54
LEU A  55
LYS A  56
ASN A  50
 None
 1.15A 4g19D-4ux5A:
undetectable		 4g19D-4ux5A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzu 3E6 ANTIBODY FAB
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE A  83
LEU A  81
LYS A  19
ASN A  84
 None
 1.49A 4g19D-4xzuA:
undetectable		 4g19D-4xzuA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
IRON-SULFUR SUBUNIT

(Sulfurisphaera
tokodaii) 		PF00111
(Fer2)
PF01799
(Fer2_2) 		4 ILE C  79
LEU C  14
LYS C  15
ASN C  60
 None
None
None
PEG  C 203 (-3.2A)
 1.49A 4g19D-4zohC:
undetectable		 4g19D-4zohC:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dku PREX DNA POLYMERASE

(Plasmodium
falciparum) 		PF00476
(DNA_pol_A)
PF01612
(DNA_pol_A_exo1) 		4 ILE A 157
LEU A 247
LYS A 244
ASN A 156
 None
 1.12A 4g19D-5dkuA:
undetectable		 4g19D-5dkuA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7g IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650

(Bacteroides
ovatus) 		no annotation 4 ILE A 147
LEU A 206
LYS A 148
ASN A 228
 None
 1.49A 4g19D-5e7gA:
undetectable		 4g19D-5e7gA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7g IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650

(Bacteroides
ovatus) 		no annotation 4 ILE A 486
LEU A 389
LYS A 390
ASN A 317
 None
 1.08A 4g19D-5e7gA:
undetectable		 4g19D-5e7gA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7h IPT/TIG
DOMAIN-CONTAINING
PROTEIN BACOVA_02650

(Bacteroides
ovatus) 		PF01833
(TIG) 		4 ILE A 486
LEU A 389
LYS A 390
ASN A 317
 None
 1.06A 4g19D-5e7hA:
undetectable		 4g19D-5e7hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey0 GTP-SENSING
TRANSCRIPTIONAL
PLEIOTROPIC
REPRESSOR CODY

(Staphylococcus
aureus) 		no annotation 4 ILE B  62
LEU B  57
LYS B  58
ASN B  38
 None
 1.03A 4g19D-5ey0B:
undetectable		 4g19D-5ey0B:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ

(Bacillus
amyloliquefaciens) 		PF12704
(MacB_PCD) 		4 ILE A  46
LEU A  49
LYS A  50
ASN A  83
 None
 1.46A 4g19D-5f9qA:
undetectable		 4g19D-5f9qA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs0 HEAVY CHAIN
(ANTI-LID)

(Mus musculus) 		no annotation 4 ILE X  68
LEU X  64
LYS X  65
ASN X  84
 None
 1.34A 4g19D-5gs0X:
undetectable		 4g19D-5gs0X:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		4 ILE A 751
LEU A 748
LYS A 749
ASN A 752
 None
 1.07A 4g19D-5hdhA:
undetectable		 4g19D-5hdhA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i7m DNA PRIMASE LARGE
SUBUNIT

(Homo sapiens) 		PF04104
(DNA_primase_lrg) 		4 ILE A 316
LEU A 313
LYS A 314
ASN A 445
 None
 1.02A 4g19D-5i7mA:
undetectable		 4g19D-5i7mA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig4 PREDICTED PROTEIN

(Nematostella
vectensis) 		PF08332
(CaMKII_AD) 		4 ILE A 463
LEU A 372
LYS A 371
ASN A 461
 None
 1.21A 4g19D-5ig4A:
undetectable		 4g19D-5ig4A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jld ARGINYL-TRNA
SYNTHETASE, PUTATIVE

(Plasmodium
falciparum) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 ILE A 118
LEU A 165
LYS A 166
ASN A 117
 None
 1.27A 4g19D-5jldA:
undetectable		 4g19D-5jldA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzt PEPTIDE/NICKEL
TRANSPORT SYSTEM
SUBSTRATE-BINDING
PROTEIN

(Listeria
monocytogenes) 		PF00496
(SBP_bac_5) 		4 ILE A 255
LEU A 252
LYS A 253
ASN A 256
 None
 1.39A 4g19D-5kztA:
undetectable		 4g19D-5kztA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlc 50S RIBOSOMAL
PROTEIN L15,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF00828
(Ribosomal_L27A) 		4 ILE N 200
LEU N 198
LYS N 199
ASN N 161
 None
None
G  A 648 ( 2.7A)
A  A 639 ( 2.8A)
 1.43A 4g19D-5mlcN:
undetectable		 4g19D-5mlcN:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqr CONDENSIN COMPLEX
SUBUNIT 3

(Schizosaccharomyces
pombe) 		no annotation 4 ILE A 774
LEU A 772
LYS A 773
ASN A 740
 None
 1.03A 4g19D-5oqrA:
undetectable		 4g19D-5oqrA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vsl RADICAL S-ADENOSYL
METHIONINE
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF04055
(Radical_SAM)
PF13353
(Fer4_12) 		4 ILE A 121
LEU A 118
LYS A 120
ASN A  77
 None
 1.29A 4g19D-5vslA:
undetectable		 4g19D-5vslA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yeu -

(-) 		no annotation 4 ILE A 391
LEU A 370
LYS A 389
ASN A 417
 None
 1.22A 4g19D-5yeuA:
undetectable		 4g19D-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywf 2H4 HEAVY CHAIN

(Mus musculus) 		no annotation 4 ILE B  83
LEU B  81
LYS B  19
ASN B  84
 None
 1.39A 4g19D-5ywfB:
undetectable		 4g19D-5ywfB:
undetectable