SIMILAR PATTERNS OF AMINO ACIDS FOR 4FZV_A_SAMA401_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bf2 ISOAMYLASE

(Pseudomonas
amyloderamosa) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ASP A 179
ARG A 174
ASP A 370
 None
 0.87A 4fzvA-1bf2A:
undetectable		 4fzvA-1bf2A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		3 ASP A  42
ARG A  20
ASP A 130
 None
 0.88A 4fzvA-1e3hA:
undetectable		 4fzvA-1e3hA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fkm PROTEIN (GYP1P)

(Saccharomyces
cerevisiae) 		PF00566
(RabGAP-TBC) 		3 ASP A 382
ARG A 490
ASP A 340
 None
 0.87A 4fzvA-1fkmA:
undetectable		 4fzvA-1fkmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ASP B 856
ARG B 377
ASP B 881
 None
 0.79A 4fzvA-1gl9B:
undetectable		 4fzvA-1gl9B:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gs9 APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		3 ASP A 151
ARG A 103
ASP A 110
 None
 0.84A 4fzvA-1gs9A:
undetectable		 4fzvA-1gs9A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gsq GLUTATHIONE
S-TRANSFERASE

(Todarodes
pacificus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		3 ASP A  77
ARG A  72
ASP A  88
 None
 0.78A 4fzvA-1gsqA:
undetectable		 4fzvA-1gsqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg0 L-ASPARAGINASE

(Dickeya
chrysanthemi) 		PF00710
(Asparaginase) 		3 ASP A 130
ARG A 122
ASP A 175
 None
 0.79A 4fzvA-1hg0A:
undetectable		 4fzvA-1hg0A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hww ALPHA-MANNOSIDASE II

(Drosophila
melanogaster) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		3 ASP A 429
ARG A 430
ASP A 169
 None
 0.83A 4fzvA-1hwwA:
undetectable		 4fzvA-1hwwA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2u OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Escherichia
coli) 		PF00215
(OMPdecase) 		3 ASP A  34
ARG A  64
ASP A  27
 None
 0.78A 4fzvA-1l2uA:
undetectable		 4fzvA-1l2uA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 ASP A 518
ARG A 545
ASP A   9
 None
 0.88A 4fzvA-1qhoA:
undetectable		 4fzvA-1qhoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Wolinella
succinogenes) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ASP A 302
ARG A 306
ASP A  78
 None
 0.83A 4fzvA-1qlbA:
undetectable		 4fzvA-1qlbA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxo CHORISMATE SYNTHASE

(Streptococcus
pneumoniae) 		PF01264
(Chorismate_synt) 		3 ASP A 123
ARG A 125
ASP A 112
 None
 0.82A 4fzvA-1qxoA:
undetectable		 4fzvA-1qxoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		3 ASP A 483
ARG A 487
ASP A 386
 None
 0.85A 4fzvA-1ut9A:
undetectable		 4fzvA-1ut9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		3 ASP A 412
ARG A 415
ASP A   4
 None
 0.79A 4fzvA-1v4gA:
undetectable		 4fzvA-1v4gA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT

(Blastochloris
viridis) 		PF02276
(CytoC_RC) 		3 ASP C 304
ARG C 146
ASP C 238
 None
 0.87A 4fzvA-1vrnC:
undetectable		 4fzvA-1vrnC:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w52 PANCREATIC LIPASE
RELATED PROTEIN 2

(Equus caballus) 		PF00151
(Lipase)
PF01477
(PLAT) 		3 ASP X 107
ARG X  38
ASP X  85
 None
 0.86A 4fzvA-1w52X:
undetectable		 4fzvA-1w52X:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		3 ASP A 136
ARG A 137
ASP A 468
 None
 0.85A 4fzvA-1yisA:
undetectable		 4fzvA-1yisA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		3 ASP A 195
ARG A  91
ASP A 221
 None
 0.84A 4fzvA-1z6rA:
undetectable		 4fzvA-1z6rA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeu HYPOTHETICAL PROTEIN
MJ0158

(Methanocaldococcus
jannaschii) 		PF03841
(SelA) 		3 ASP A 351
ARG A 350
ASP A  28
 None
SO4  A1010 (-2.6A)
None
 0.73A 4fzvA-2aeuA:
undetectable		 4fzvA-2aeuA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an2 P332G A333S DOUBLE
MUTANT OF NITRIC
OXIDE SYNTHASE FROM
BACILLUS SUBTILIS

(Bacillus
subtilis) 		PF02898
(NO_synthase) 		3 ASP A 141
ARG A 128
ASP A 247
 None
ARG  A2000 (-4.0A)
None
 0.89A 4fzvA-2an2A:
undetectable		 4fzvA-2an2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axq SACCHAROPINE
DEHYDROGENASE

(Saccharomyces
cerevisiae) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		3 ASP A 337
ARG A 176
ASP A 266
 None
 0.86A 4fzvA-2axqA:
4.2		 4fzvA-2axqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9e NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 258
ARG A 263
ASP A 305
 SAM  A1201 (-2.6A)
SAM  A1201 (-3.9A)
SAM  A1201 (-3.7A)
 0.80A 4fzvA-2b9eA:
23.2		 4fzvA-2b9eA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6d GLUCOAMYLASE GLU1

(Saccharomycopsis
fibuligera) 		PF00723
(Glyco_hydro_15) 		3 ASP A 160
ARG A 156
ASP A  84
 None
 0.81A 4fzvA-2f6dA:
undetectable		 4fzvA-2f6dA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk0 L-ASPARAGINASE

(Pectobacterium
carotovorum) 		PF00710
(Asparaginase) 		3 ASP A 130
ARG A 122
ASP A 175
 None
 0.76A 4fzvA-2jk0A:
undetectable		 4fzvA-2jk0A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k4z DSRR

(Allochromatium
vinosum) 		PF01521
(Fe-S_biosyn) 		3 ASP A  51
ARG A  27
ASP A  66
 None
 0.72A 4fzvA-2k4zA:
undetectable		 4fzvA-2k4zA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbq HARMONIN

(Homo sapiens) 		no annotation 3 ASP A  14
ARG A  10
ASP A  20
 None
 0.81A 4fzvA-2kbqA:
undetectable		 4fzvA-2kbqA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m5t HUMAN RHINOVIRUS 2A
PROTEINASE

(Rhinovirus C) 		PF00947
(Pico_P2A) 		3 ASP A 131
ARG A 133
ASP A  75
 None
 0.65A 4fzvA-2m5tA:
undetectable		 4fzvA-2m5tA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbl PUTATIVE
ESTERASE/LIPASE/THIO
ESTERASE

(Ruegeria sp.
TM1040) 		PF07859
(Abhydrolase_3) 		3 ASP A  53
ARG A  31
ASP A  77
 None
 0.80A 4fzvA-2pblA:
undetectable		 4fzvA-2pblA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		3 ASP A   3
ARG A 137
ASP A  43
 None
 0.82A 4fzvA-2rcqA:
undetectable		 4fzvA-2rcqA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		3 ASP A   3
ARG A 137
ASP A  45
 None
 0.75A 4fzvA-2rcqA:
undetectable		 4fzvA-2rcqA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ASP A 612
ARG A 642
ASP A 104
 None
 0.79A 4fzvA-2va8A:
undetectable		 4fzvA-2va8A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vak SIGMA A

(Avian
orthoreovirus) 		PF03084
(Sigma_1_2) 		3 ASP A 257
ARG A 252
ASP A 286
 None
 0.81A 4fzvA-2vakA:
undetectable		 4fzvA-2vakA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vp3 VP39

(Vaccinia virus) 		PF01358
(PARP_regulatory) 		3 ASP A  95
ARG A  97
ASP A 138
 SAH  A 400 (-2.6A)
SAH  A 400 (-3.9A)
SAH  A 400 (-3.7A)
 0.55A 4fzvA-2vp3A:
7.0		 4fzvA-2vp3A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x7x SENSOR PROTEIN

(Bacteroides
thetaiotaomicron) 		PF13407
(Peripla_BP_4) 		3 ASP A 120
ARG A 121
ASP A 248
 FRU  A1335 (-2.5A)
FRU  A1335 (-4.1A)
FRU  A1335 (-2.8A)
 0.83A 4fzvA-2x7xA:
undetectable		 4fzvA-2x7xA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z81 TOLL-LIKE RECEPTOR
2, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13306
(LRR_5)
PF13516
(LRR_6)
PF13855
(LRR_8) 		3 ASP A  58
ARG A  39
ASP A 106
 None
 0.81A 4fzvA-2z81A:
undetectable		 4fzvA-2z81A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5w PP2A-SPECIFIC
METHYLESTERASE PME-1

(Homo sapiens) 		PF12697
(Abhydrolase_6) 		3 ASP P 354
ARG P 222
ASP P 181
 None
 0.71A 4fzvA-3c5wP:
undetectable		 4fzvA-3c5wP:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5m NMRA-LIKE FAMILY
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF05368
(NmrA) 		3 ASP A 186
ARG A 218
ASP A 269
 None
 0.81A 4fzvA-3e5mA:
4.4		 4fzvA-3e5mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis) 		PF13673
(Acetyltransf_10) 		3 ASP A 177
ARG A 163
ASP A  12
 None
 0.77A 4fzvA-3frmA:
undetectable		 4fzvA-3frmA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwb PEPTIDASE M16
INACTIVE DOMAIN
FAMILY PROTEIN

(Pseudomonas
protegens) 		PF05193
(Peptidase_M16_C) 		3 ASP A  37
ARG A 100
ASP A 367
 None
 0.86A 4fzvA-3gwbA:
undetectable		 4fzvA-3gwbA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		3 ASP A 109
ARG A 153
ASP A  75
 None
 0.83A 4fzvA-3h7uA:
undetectable		 4fzvA-3h7uA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		3 ASP A 218
ARG A 272
ASP A 240
 None
 0.87A 4fzvA-3i2nA:
undetectable		 4fzvA-3i2nA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6e MUCONATE
CYCLOISOMERASE I

(Ruegeria
pomeroyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 268
ARG A 239
ASP A 243
 NA  A 387 ( 4.2A)
None
None
 0.82A 4fzvA-3i6eA:
undetectable		 4fzvA-3i6eA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0z PUTATIVE POLYKETIDE
CYCLASE

(Bacillus cereus) 		PF07366
(SnoaL) 		3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.71A 4fzvA-3k0zA:
undetectable		 4fzvA-3k0zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lah METHYL-ACCEPTING
CHEMOTAXIS PROTEIN

(Caldanaerobacter
subterraneus) 		PF07700
(HNOB) 		3 ASP A  45
ARG A 135
ASP A  42
 None
HEM  A 200 (-3.6A)
None
 0.69A 4fzvA-3lahA:
undetectable		 4fzvA-3lahA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3moi PROBABLE
DEHYDROGENASE

(Bordetella
bronchiseptica) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 ASP A 155
ARG A 159
ASP A 239
 None
 0.78A 4fzvA-3moiA:
undetectable		 4fzvA-3moiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwr A RUBISCO-LIKE
PROTEIN

(Paraburkholderia
fungorum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 ASP A 192
ARG A 399
ASP A 157
 SO4  A 434 ( 4.8A)
SO4  A 434 (-3.1A)
None
 0.82A 4fzvA-3nwrA:
undetectable		 4fzvA-3nwrA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pps LACCASE

(Thielavia
arenaria) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ASP A  76
ARG A  33
ASP A 157
 None
 0.85A 4fzvA-3ppsA:
undetectable		 4fzvA-3ppsA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psg PEPSINOGEN

(Sus scrofa) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		3 ASP A 149
ARG A 315
ASP A 142
 None
 0.75A 4fzvA-3psgA:
undetectable		 4fzvA-3psgA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		3 ASP A 626
ARG A 629
ASP A 668
 None
 0.77A 4fzvA-3sfzA:
undetectable		 4fzvA-3sfzA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tos CALS11

(Micromonospora
echinospora) 		PF05711
(TylF) 		3 ASP A 151
ARG A  91
ASP A 145
 None
 0.73A 4fzvA-3tosA:
undetectable		 4fzvA-3tosA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u95 GLYCOSIDE HYDROLASE,
FAMILY 4

(Thermotoga
neapolitana) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		3 ASP A 294
ARG A 299
ASP A 267
 None
None
MN  A 601 ( 4.6A)
 0.86A 4fzvA-3u95A:
4.6		 4fzvA-3u95A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw2 PHOSPHOGLUCOMUTASE/P
HOSPHOMANNOMUTASE
FAMILY PROTEIN

(Burkholderia
thailandensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ASP A 247
ARG A 248
ASP A  11
 ZN  A 474 ( 2.5A)
GOL  A 472 ( 4.0A)
None
 0.88A 4fzvA-3uw2A:
undetectable		 4fzvA-3uw2A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wec CYTOCHROME P450

(Rhodococcus
erythropolis) 		PF00067
(p450) 		3 ASP A 241
ARG A 212
ASP A  94
 None
 0.82A 4fzvA-3wecA:
undetectable		 4fzvA-3wecA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zsc PECTATE
TRISACCHARIDE-LYASE

(Thermotoga
maritima) 		PF00544
(Pec_lyase_C) 		3 ASP A 143
ARG A 197
ASP A 115
 None
AQA  A1338 (-3.2A)
None
 0.86A 4fzvA-3zscA:
undetectable		 4fzvA-3zscA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af1 PEPTIDE CHAIN
RELEASE FACTOR
SUBUNIT 1

(Halobacterium
salinarum) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		3 ASP A 329
ARG A 347
ASP A 373
 None
 0.87A 4fzvA-4af1A:
undetectable		 4fzvA-4af1A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB

(Geobacillus
stearothermophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ASP A  64
ARG A  27
ASP A  53
 None
 0.87A 4fzvA-4fnqA:
undetectable		 4fzvA-4fnqA:
18.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 204
ARG A 209
ASP A 255
 SAM  A 401 (-2.9A)
SAM  A 401 (-3.6A)
SAM  A 401 (-3.7A)
 0.02A 4fzvA-4fzvA:
63.9		 4fzvA-4fzvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3n DNA GYRASE SUBUNIT A

(Mycobacterium
tuberculosis) 		PF03989
(DNA_gyraseA_C) 		3 ASP A 565
ARG A 615
ASP A 515
 None
 0.78A 4fzvA-4g3nA:
undetectable		 4fzvA-4g3nA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0k CD276 ANTIGEN

(Mus musculus) 		PF07686
(V-set)
PF13927
(Ig_3) 		3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.76A 4fzvA-4i0kA:
undetectable		 4fzvA-4i0kA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9x PROTEIN UL141

(Human
betaherpesvirus
5) 		PF16758
(UL141) 		3 ASP A  91
ARG A 110
ASP A  88
 None
 0.89A 4fzvA-4i9xA:
undetectable		 4fzvA-4i9xA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n27 BACTERIAL
TRANSFERASE
HEXAPEPTIDE REPEAT

(Brucella
abortus) 		PF00132
(Hexapep) 		3 ASP A  48
ARG A  46
ASP A  69
 PE5  A 202 ( 4.0A)
PE5  A 202 (-4.0A)
PE5  A 202 (-3.9A)
 0.88A 4fzvA-4n27A:
undetectable		 4fzvA-4n27A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qg5 PUTATIVE
PHOSPHOGLUCOMUTASE

(Leishmania
major) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ASP A 303
ARG A 304
ASP A  57
 MG  A 601 (-1.7A)
MG  A 601 ( 4.7A)
None
 0.83A 4fzvA-4qg5A:
undetectable		 4fzvA-4qg5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		3 ASP A 183
ARG A 184
ASP A 202
 EDO  A 505 ( 4.3A)
None
SO4  A 506 (-2.8A)
 0.82A 4fzvA-4rgkA:
undetectable		 4fzvA-4rgkA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tlv ADP-RIBOSYLATING
TOXIN CARDS

(Mycoplasma
pneumoniae) 		PF02917
(Pertussis_S1) 		3 ASP A 589
ARG A 530
ASP A 586
 None
None
GOL  A 605 ( 4.8A)
 0.83A 4fzvA-4tlvA:
undetectable		 4fzvA-4tlvA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd1 ACETOACETATE-COA
LIGASE

(Streptomyces
lividans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		3 ASP A 406
ARG A 402
ASP A 414
 EDO  A 708 (-4.7A)
None
None
 0.87A 4fzvA-4wd1A:
2.5		 4fzvA-4wd1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xl5 BGFP-A

(synthetic
construct) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		3 ASP C  74
ARG C  76
ASP C  43
 None
 0.87A 4fzvA-4xl5C:
undetectable		 4fzvA-4xl5C:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydh FORMIN-LIKE PROTEIN
1

(Homo sapiens) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASP A 294
ARG A 305
ASP A 287
 None
 0.82A 4fzvA-4ydhA:
undetectable		 4fzvA-4ydhA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2e DNA GYRASE SUBUNIT A

(Streptococcus
pneumoniae) 		PF00521
(DNA_topoisoIV) 		3 ASP A 366
ARG A 362
ASP A 450
 None
 0.87A 4fzvA-4z2eA:
undetectable		 4fzvA-4z2eA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zc0 REPLICATIVE DNA
HELICASE

(Helicobacter
pylori) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		3 ASP A 381
ARG A 336
ASP A 374
 None
 0.74A 4fzvA-4zc0A:
undetectable		 4fzvA-4zc0A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv6 ALPHAREP-7

(synthetic
construct) 		PF13646
(HEAT_2) 		3 ASP A 120
ARG A 122
ASP A  89
 None
 0.88A 4fzvA-4zv6A:
undetectable		 4fzvA-4zv6A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ady GTPASE HFLX

(Escherichia
coli) 		PF01926
(MMR_HSR1)
PF13167
(GTP-bdg_N)
PF16360
(GTP-bdg_M) 		3 ASP 6  81
ARG 6 103
ASP 6  26
 None
 0.79A 4fzvA-5ady6:
undetectable		 4fzvA-5ady6:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7n MTA/SAH NUCLEOSIDASE

(Aeromonas
hydrophila) 		PF01048
(PNP_UDP_1) 		3 ASP A 116
ARG A 187
ASP A 109
 None
 0.81A 4fzvA-5b7nA:
undetectable		 4fzvA-5b7nA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp1 MYCOCEROSIC ACID
SYNTHASE

(Mycolicibacterium
smegmatis) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ASP A 254
ARG A 252
ASP A 259
 None
 0.84A 4fzvA-5bp1A:
undetectable		 4fzvA-5bp1A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5diy HYALURONIDASE

(Thermobaculum
terrenum) 		PF07555
(NAGidase) 		3 ASP A 143
ARG A 147
ASP A 130
 None
 0.79A 4fzvA-5diyA:
undetectable		 4fzvA-5diyA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA

(Homo sapiens;
Homo sapiens) 		no annotation
PF00041
(fn3)
PF09240
(IL6Ra-bind) 		3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.78A 4fzvA-5dwuA:
undetectable		 4fzvA-5dwuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnm VITAMIN D(3)
25-HYDROXYLASE

(Pseudonocardia
autotrophica) 		PF00067
(p450) 		3 ASP A  66
ARG A  68
ASP A  94
 None
 0.69A 4fzvA-5gnmA:
undetectable		 4fzvA-5gnmA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt5 PECTATE LYASE

(Paenibacillus
sp. 0602) 		no annotation 3 ASP A 178
ARG A 276
ASP A 150
 None
 0.71A 4fzvA-5gt5A:
undetectable		 4fzvA-5gt5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs1 LANOSTEROL 14-ALPHA
DEMETHYLASE

(Saccharomyces
cerevisiae) 		PF00067
(p450) 		3 ASP A  54
ARG A  52
ASP A 390
 None
 0.82A 4fzvA-5hs1A:
undetectable		 4fzvA-5hs1A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j46 PEPTIDE DEFORMYLASE

(Burkholderia
multivorans) 		PF01327
(Pep_deformylase) 		3 ASP A  39
ARG A  41
ASP A  36
 None
 0.56A 4fzvA-5j46A:
undetectable		 4fzvA-5j46A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jh1 ALDOSE REDUCTASE,
AKR4C7

(Zea mays) 		PF00248
(Aldo_ket_red) 		3 ASP A 106
ARG A 149
ASP A  72
 None
 0.88A 4fzvA-5jh1A:
undetectable		 4fzvA-5jh1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE

([Candida]
glabrata) 		PF00067
(p450) 		3 ASP A  55
ARG A  53
ASP A 391
 None
 0.85A 4fzvA-5jlcA:
undetectable		 4fzvA-5jlcA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp9 CMP
5-HYDROXYMETHYLASE

(Streptomyces
rimofaciens) 		PF00303
(Thymidylat_synt) 		3 ASP A 305
ARG A 306
ASP A 274
 None
 0.82A 4fzvA-5jp9A:
undetectable		 4fzvA-5jp9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdj F5/8 TYPE C DOMAIN
PROTEIN

(Clostridium
perfringens) 		no annotation 3 ASP B 871
ARG B 851
ASP B 895
 None
 0.86A 4fzvA-5kdjB:
undetectable		 4fzvA-5kdjB:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koi ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]

(Brucella
abortus) 		PF13561
(adh_short_C2) 		3 ASP A  87
ARG A   9
ASP A 138
 None
 0.85A 4fzvA-5koiA:
4.7		 4fzvA-5koiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg8 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
6

(Schizosaccharomyces
pombe) 		no annotation 3 ASP B 654
ARG B 656
ASP B 676
 None
 0.85A 4fzvA-5mg8B:
undetectable		 4fzvA-5mg8B:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mjv CAPSID SUBUNIT VP1
CAPSID SUBUNIT VP0

(Parechovirus A;
Parechovirus A) 		no annotation
PF00073
(Rhv) 		3 ASP A 134
ARG A 139
ASP C 288
 None
 0.88A 4fzvA-5mjvA:
undetectable		 4fzvA-5mjvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzv NANOBODY 22E11

(Lama glama) 		no annotation 3 ASP D  66
ARG D  67
ASP D  62
 None
 0.79A 4fzvA-5mzvD:
undetectable		 4fzvA-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocp -

(-) 		no annotation 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.87A 4fzvA-5ocpA:
undetectable		 4fzvA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogx CYTOCHROME P450
REDUCTASE

(Amycolatopsis
methanolica) 		no annotation 3 ASP A 247
ARG A 164
ASP A 272
 None
 0.77A 4fzvA-5ogxA:
undetectable		 4fzvA-5ogxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5pep PEPSIN

(Sus scrofa) 		PF00026
(Asp) 		3 ASP A 149
ARG A 316
ASP A 142
 None
 0.81A 4fzvA-5pepA:
undetectable		 4fzvA-5pepA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5pq9 BROMODOMAIN-CONTAINI
NG PROTEIN 1

(Homo sapiens) 		PF00439
(Bromodomain) 		3 ASP A  50
ARG A  53
ASP A  76
 None
 0.88A 4fzvA-5pq9A:
undetectable		 4fzvA-5pq9A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tg8 HEMAGGLUTININ HA1
CHAIN

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ASP A 298
ARG A 300
ASP A 271
 None
 0.89A 4fzvA-5tg8A:
undetectable		 4fzvA-5tg8A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vpu 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Acinetobacter
baumannii) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ASP A 488
ARG A 508
ASP A  56
 None
 0.77A 4fzvA-5vpuA:
2.7		 4fzvA-5vpuA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4t CADHERIN 23

(Danio rerio) 		no annotation 3 ASP C 237
ARG C 244
ASP C 208
 CA  C 407 (-2.7A)
None
None
 0.61A 4fzvA-5w4tC:
undetectable		 4fzvA-5w4tC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wm4 SALICYLATE-AMP
LIGASE

(Streptomyces
gandocaensis) 		no annotation 3 ASP A 226
ARG A  37
ASP A 204
 None
 0.69A 4fzvA-5wm4A:
undetectable		 4fzvA-5wm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Bifidobacterium
bifidum) 		PF11308
(Glyco_hydro_129) 		3 ASP A 128
ARG A 173
ASP A 122
 None
 0.81A 4fzvA-5wzrA:
undetectable		 4fzvA-5wzrA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydn GENE PRODUCT J

(Escherichia
virus Mu) 		no annotation 3 ASP A  19
ARG A  15
ASP A  32
 None
 0.81A 4fzvA-5ydnA:
undetectable		 4fzvA-5ydnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0e 1260 ANTIBODY, HEAVY
CHAIN

(Homo sapiens) 		no annotation 3 ASP B  95
ARG B  96
ASP B  58
 None
 0.73A 4fzvA-6b0eB:
undetectable		 4fzvA-6b0eB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dg4 ULP1-LIKE SUMO
PROTEASE

(Chaetomium
thermophilum) 		no annotation 3 ASP A  48
ARG A  47
ASP A  62
 None
GOL  A 303 (-2.6A)
None
 0.59A 4fzvA-6dg4A:
undetectable		 4fzvA-6dg4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A 856
ARG A 900
ASP A 793
 None
 0.83A 4fzvA-6eojA:
undetectable		 4fzvA-6eojA:
13.78