SIMILAR PATTERNS OF AMINO ACIDS FOR 4FR0_A_SAMA401_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b63 | MUTL (Escherichiacoli) |
PF01119(DNA_mis_repair)PF13589(HATPase_c_3) | 5 | GLY A 50LEU A 53ILE A 44VAL A 27LEU A 30 | None | 1.05A | 4fr0A-1b63A:undetectable | 4fr0A-1b63A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fue | FLAVODOXIN (Helicobacterpylori) |
PF00258(Flavodoxin_1) | 5 | GLY A 99GLY A 58PHE A 134ILE A 100LEU A 86 | NoneFMN A 165 (-3.8A)NoneNoneFMN A 165 (-3.7A) | 1.14A | 4fr0A-1fueA:undetectable | 4fr0A-1fueA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4y | LIVERCARBOXYLESTERASE (Oryctolaguscuniculus) |
PF00135(COesterase) | 5 | GLY A 210GLY A 131LEU A 127ILE A 205VAL A 164 | None | 1.11A | 4fr0A-1k4yA:undetectable | 4fr0A-1k4yA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llu | ALCOHOLDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 125GLY A 66ILE A 38ASN A 123VAL A 130 | None | 0.97A | 4fr0A-1lluA:5.6 | 4fr0A-1lluA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llu | ALCOHOLDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 125LEU A 153ILE A 38ASN A 123VAL A 130 | None | 1.04A | 4fr0A-1lluA:5.6 | 4fr0A-1lluA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oe5 | SINGLE-STRANDSELECTIVEMONOFUNCTIONALURACIL DNAGLYCOSYLASE (Xenopus laevis) |
no annotation | 5 | GLY A 110GLY A 149ASN A 113VAL A 115LEU A 119 | None | 1.13A | 4fr0A-1oe5A:undetectable | 4fr0A-1oe5A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pjq | SIROHEME SYNTHASE (Salmonellaenterica) |
PF00590(TP_methylase)PF10414(CysG_dimeriser)PF13241(NAD_binding_7)PF14824(Sirohm_synth_M) | 5 | GLY A 421LEU A 423PHE A 380ILE A 440VAL A 445 | None | 1.14A | 4fr0A-1pjqA:4.6 | 4fr0A-1pjqA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1puj | CONSERVEDHYPOTHETICAL PROTEINYLQF (Bacillussubtilis) |
PF01926(MMR_HSR1) | 5 | GLY A 127GLY A 174ASP A 171LEU A 176VAL A 131 | NoneGNP A 501 (-3.1A) MG A9001 ( 4.2A)NoneGNP A 501 (-4.2A) | 0.96A | 4fr0A-1pujA:2.0 | 4fr0A-1pujA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sus | CAFFEOYL-COAO-METHYLTRANSFERASE (Medicago sativa) |
PF01596(Methyltransf_3) | 5 | GLY A 87ASP A 165LEU A 94ILE A 160LEU A 108 | SAH A 301 (-3.4A)SAH A 301 ( 2.8A)NoneNoneNone | 1.09A | 4fr0A-1susA:12.7 | 4fr0A-1susA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v7l | 3-ISOPROPYLMALATEDEHYDRATASE SMALLSUBUNIT (Pyrococcushorikoshii) |
PF00694(Aconitase_C) | 5 | GLY A 81LEU A 103ILE A 96VAL A 145LEU A 142 | None | 1.06A | 4fr0A-1v7lA:undetectable | 4fr0A-1v7lA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmj | HYPOTHETICAL PROTEINTM0723 (Thermotogamaritima) |
PF01894(UPF0047) | 5 | GLY A 99ILE A 52GLU A 117ASN A 42VAL A 102 | None | 1.03A | 4fr0A-1vmjA:undetectable | 4fr0A-1vmjA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xea | OXIDOREDUCTASE,GFO/IDH/MOCA FAMILY (Vibrio cholerae) |
PF01408(GFO_IDH_MocA) | 5 | GLY A 9GLY A 11LEU A 19GLN A 15ILE A 8 | None | 0.96A | 4fr0A-1xeaA:4.6 | 4fr0A-1xeaA:24.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcj | PEROXISOMALBIFUNCTIONAL ENZYME (Rattusnorvegicus) |
PF00725(3HCDH)PF02737(3HCDH_N) | 6 | GLY A 303GLY A 305GLN A 331GLU A 394ASN A 408LEU A 387 | None | 1.39A | 4fr0A-1zcjA:6.1 | 4fr0A-1zcjA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aan | AURACYANIN A (Chloroflexusaurantiacus) |
PF00127(Copper-bind) | 5 | GLY A 66ILE A 122ASN A 93VAL A 63LEU A 62 | None | 0.98A | 4fr0A-2aanA:undetectable | 4fr0A-2aanA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayv | UBIQUITIN-CONJUGATING ENZYME E2 (Toxoplasmagondii) |
PF00179(UQ_con) | 5 | GLY A 82LEU A 119ILE A 106ASN A 53VAL A 67 | NoneUNX A 154 (-4.9A)NoneNoneNone | 0.99A | 4fr0A-2ayvA:undetectable | 4fr0A-2ayvA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cas | CANINE PARVOVIRUSEMPTY CAPSID (STRAIND) VIRAL PROTEIN 2 (Carnivoreprotoparvovirus1) |
PF00740(Parvo_coat) | 5 | GLY A 496LEU A 498ILE A 246ASN A 180VAL A 250 | None | 1.11A | 4fr0A-2casA:undetectable | 4fr0A-2casA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfb | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Synechococcuselongatus) |
PF00202(Aminotran_3) | 5 | GLY A 342GLY A 386LEU A 378PHE A 345VAL A 318 | None | 1.05A | 4fr0A-2cfbA:undetectable | 4fr0A-2cfbA:24.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2huf | ALANINE GLYOXYLATEAMINOTRANSFERASE (Aedes aegypti) |
PF00266(Aminotran_5) | 5 | GLY A 162LEU A 150GLN A 161GLU A 196LEU A 169 | None | 1.12A | 4fr0A-2hufA:undetectable | 4fr0A-2hufA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ihy | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusaureus) |
PF00005(ABC_tran) | 5 | LEU A 36PHE A 203ILE A 204GLU A 205ASN A 236 | None | 0.83A | 4fr0A-2ihyA:undetectable | 4fr0A-2ihyA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j7p | CELL DIVISIONPROTEIN FTSY (Thermusaquaticus) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | GLY D 109GLY D 194ASP D 191LEU D 196VAL D 113 | NoneGNP D1400 (-3.3A) MG D1401 ( 4.0A)NoneGNP D1400 (-4.1A) | 0.97A | 4fr0A-2j7pD:2.3 | 4fr0A-2j7pD:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lxn | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] SUBUNIT A (Methanocaldococcusjannaschii) |
PF00117(GATase) | 5 | GLY A 46GLY A 184LEU A 19ILE A 47LEU A 73 | None | 1.09A | 4fr0A-2lxnA:undetectable | 4fr0A-2lxnA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2opj | O-SUCCINYLBENZOATE-COA SYNTHASE (Thermobifidafusca) |
PF13378(MR_MLE_C) | 5 | GLY A 239LEU A 246GLU A 56VAL A 204LEU A 207 | None | 1.13A | 4fr0A-2opjA:undetectable | 4fr0A-2opjA:25.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgx | UBIQUITIN-CONJUGATING ENZYME E2 Q1 (Homo sapiens) |
PF00179(UQ_con) | 5 | GLY A 101LEU A 98ILE A 126ASN A 71VAL A 85 | None | 1.12A | 4fr0A-2qgxA:undetectable | 4fr0A-2qgxA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgj | FLAVIN-CONTAININGMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 5 | GLY A 16ASP A 329ILE A 7VAL A 162LEU A 161 | None | 1.04A | 4fr0A-2rgjA:undetectable | 4fr0A-2rgjA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 5 | GLY A 447LEU A 401ILE A 513ASN A 474VAL A 468 | None | 1.08A | 4fr0A-2wk2A:undetectable | 4fr0A-2wk2A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y7c | TYPE I RESTRICTIONENZYME ECOKI MPROTEIN (Escherichiacoli) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 5 | LEU B 290ILE B 296ASN B 266VAL B 308LEU B 355 | None | 0.86A | 4fr0A-2y7cB:9.8 | 4fr0A-2y7cB:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aat | ASPARTATEAMINOTRANSFERASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | GLY A 358GLY A 197GLN A 356ILE A 330ASN A 194 | NoneNoneNoneNoneSO4 A 411 ( 3.1A) | 1.08A | 4fr0A-3aatA:undetectable | 4fr0A-3aatA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8y | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 5 | ASP A 133LEU A 153ILE A 184ASN A 163VAL A 187 | None | 1.14A | 4fr0A-3b8yA:undetectable | 4fr0A-3b8yA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b90 | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 5 | ASP A 133LEU A 153ILE A 184ASN A 163VAL A 187 | None | 1.13A | 4fr0A-3b90A:undetectable | 4fr0A-3b90A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cfx | UPF0100 PROTEINMA_0280 (Methanosarcinaacetivorans) |
PF13531(SBP_bac_11) | 5 | GLY A 134PHE A 254ASN A 138VAL A 257LEU A 125 | None | 1.07A | 4fr0A-3cfxA:undetectable | 4fr0A-3cfxA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cru | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | GLY A 83GLY A 84ILE A 92GLU A 96ASN A 80 | None | 1.13A | 4fr0A-3cruA:undetectable | 4fr0A-3cruA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d12 | EPHRIN-B3 (Mus musculus) |
PF00812(Ephrin) | 5 | GLY B 89LEU B 164ILE B 138VAL B 84LEU B 83 | None | 1.13A | 4fr0A-3d12B:undetectable | 4fr0A-3d12B:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d7l | LIN1944 PROTEIN (Listeriainnocua) |
PF13561(adh_short_C2) | 5 | GLY A 97LEU A 101ILE A 6ASN A 92LEU A 109 | None | 1.09A | 4fr0A-3d7lA:4.4 | 4fr0A-3d7lA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dmb | PUTATIVE GENERALSTRESS PROTEIN 26WITH A PNP-OXIDASELIKE FOLD (Xanthomonascampestris) |
PF16242(Pyrid_ox_like) | 5 | GLY A 70GLY A 24LEU A 87ILE A 83VAL A 21 | None | 1.02A | 4fr0A-3dmbA:undetectable | 4fr0A-3dmbA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eix | HTSA PROTEIN (Staphylococcusaureus) |
PF01497(Peripla_BP_2) | 6 | GLY A 205ASP A 280LEU A 207GLN A 246ILE A 262LEU A 197 | None | 1.27A | 4fr0A-3eixA:2.2 | 4fr0A-3eixA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iha | SALT-TOLERANTGLUTAMINASE (Micrococcusluteus) |
PF04960(Glutaminase) | 5 | GLY A 291ASP A 283LEU A 298ASN A 287VAL A 265 | None | 1.15A | 4fr0A-3ihaA:undetectable | 4fr0A-3ihaA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k28 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE2 (Bacillusanthracis) |
PF00202(Aminotran_3) | 5 | GLY A 358GLY A 401LEU A 394ILE A 350LEU A 333 | None | 1.14A | 4fr0A-3k28A:undetectable | 4fr0A-3k28A:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6x | SOLUTE-BINDINGPROTEIN MA_0280 (Methanosarcinaacetivorans) |
PF13531(SBP_bac_11) | 5 | GLY A 134PHE A 254ASN A 138VAL A 257LEU A 125 | None | 1.04A | 4fr0A-3k6xA:undetectable | 4fr0A-3k6xA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | GLY A 9PHE A 121ILE A 122ASN A 135VAL A 132 | None | 1.08A | 4fr0A-3kjrA:undetectable | 4fr0A-3kjrA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkd | TYPE IRESTRICTION-MODIFICATION SYSTEMMETHYLTRANSFERASESUBUNIT (Streptococcusthermophilus) |
PF02384(N6_Mtase)PF12161(HsdM_N) | 5 | GLY A 37ASP A 138ILE A 185GLU A 182ASN A 262 | None | 0.91A | 4fr0A-3lkdA:10.1 | 4fr0A-3lkdA:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3meq | ALCOHOLDEHYDROGENASE,ZINC-CONTAINING (Brucella suis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 123GLY A 64ILE A 36ASN A 121VAL A 128 | None | 1.01A | 4fr0A-3meqA:5.7 | 4fr0A-3meqA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mmp | RNA-DIRECTED RNAPOLYMERASE BETACHAIN (Escherichiavirus Qbeta) |
no annotation | 5 | GLY G 237GLY G 326LEU G 302GLN G 233ILE G 239 | None | 1.10A | 4fr0A-3mmpG:undetectable | 4fr0A-3mmpG:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqp | SUSD SUPERFAMILYPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | GLY A 75PHE A 470ILE A 471ASN A 344VAL A 347 | None | 1.01A | 4fr0A-3nqpA:undetectable | 4fr0A-3nqpA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pet | PUTATIVE ADHESIN (Bacteroidesfragilis) |
PF10988(DUF2807) | 5 | ASP A 123GLN A 148ILE A 137ASN A 144VAL A 165 | None | 1.06A | 4fr0A-3petA:undetectable | 4fr0A-3petA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q75 | FARNESYLTRANSFERASEBETA SUBUNIT (Cryptococcusneoformans) |
PF00432(Prenyltrans) | 5 | GLY B 311GLY B 313GLN B 305VAL B 9LEU B 12 | None | 1.14A | 4fr0A-3q75B:undetectable | 4fr0A-3q75B:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rao | PUTATIVELUCIFERASE-LIKEMONOOXYGENASE (Bacillus cereus) |
PF00296(Bac_luciferase) | 5 | GLY A 299GLN A 303ILE A 308VAL A 337LEU A 340 | NoneSO4 A 354 (-4.6A)NoneNoneNone | 1.10A | 4fr0A-3raoA:undetectable | 4fr0A-3raoA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2g | ZINC-CONTAININGALCOHOLDEHYDROGENASESUPERFAMILY (Cupriaviduspinatubonensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 123GLY A 64ILE A 36ASN A 121VAL A 128 | None | 1.11A | 4fr0A-3s2gA:5.9 | 4fr0A-3s2gA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2g | ZINC-CONTAININGALCOHOLDEHYDROGENASESUPERFAMILY (Cupriaviduspinatubonensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 123LEU A 151ILE A 36ASN A 121VAL A 128 | None | 1.12A | 4fr0A-3s2gA:5.9 | 4fr0A-3s2gA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8y | CHEMOTAXIS RESPONSEREGULATORPROTEIN-GLUTAMATEMETHYLESTERASE (Thermotogamaritima) |
PF00072(Response_reg) | 6 | GLY A 66GLY A 40ASP A 13LEU A 72ILE A 67GLU A 97 | NoneNone PB A 145 (-2.7A)NoneNoneNone | 1.37A | 4fr0A-3t8yA:2.5 | 4fr0A-3t8yA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uaf | TTR-52 (Caenorhabditiselegans) |
PF01060(TTR-52) | 5 | ASP A 67LEU A 47ILE A 93ASN A 71LEU A 123 | None | 1.12A | 4fr0A-3uafA:undetectable | 4fr0A-3uafA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsm | OCCLUSION-DERIVEDVIRUS ENVELOPEPROTEIN E66 (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF04850(Baculo_E66) | 5 | GLY A 132LEU A 130PHE A 193VAL A 199LEU A 200 | None | 1.00A | 4fr0A-3vsmA:undetectable | 4fr0A-3vsmA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4blq | P4 (Pseudomonasphage phi8) |
PF11602(NTPase_P4) | 5 | GLY A 81ASP A 78MET A 196GLN A 192VAL A 53 | None | 0.98A | 4fr0A-4blqA:undetectable | 4fr0A-4blqA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c23 | L-FUCULOSE KINASEFUCK (Streptococcuspneumoniae) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | GLY A 417ASP A 414ILE A 250VAL A 420LEU A 421 | None | 1.09A | 4fr0A-4c23A:undetectable | 4fr0A-4c23A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cja | BURRH (Paraburkholderiarhizoxinica) |
PF03377(TAL_effector) | 5 | GLY A 162PHE A 148ILE A 153VAL A 136LEU A 139 | None | 1.13A | 4fr0A-4cjaA:undetectable | 4fr0A-4cjaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cja | BURRH (Paraburkholderiarhizoxinica) |
PF03377(TAL_effector) | 5 | GLY A 228PHE A 214ILE A 219VAL A 202LEU A 205 | None | 1.08A | 4fr0A-4cjaA:undetectable | 4fr0A-4cjaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cja | BURRH (Paraburkholderiarhizoxinica) |
PF03377(TAL_effector) | 5 | GLY A 360PHE A 346ILE A 351VAL A 334LEU A 337 | None | 1.10A | 4fr0A-4cjaA:undetectable | 4fr0A-4cjaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cja | BURRH (Paraburkholderiarhizoxinica) |
PF03377(TAL_effector) | 5 | GLY A 492PHE A 478ILE A 483VAL A 466LEU A 469 | None | 1.05A | 4fr0A-4cjaA:undetectable | 4fr0A-4cjaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cja | BURRH (Paraburkholderiarhizoxinica) |
PF03377(TAL_effector) | 5 | GLY A 591PHE A 577ILE A 582VAL A 565LEU A 568 | None | 1.12A | 4fr0A-4cjaA:undetectable | 4fr0A-4cjaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dg5 | PHOSPHOGLYCERATEKINASE (Staphylococcusaureus) |
PF00162(PGK) | 5 | LEU A 41ILE A 47ASN A 148VAL A 18LEU A 56 | None | 1.08A | 4fr0A-4dg5A:undetectable | 4fr0A-4dg5A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f78 | D,D-DIPEPTIDASE/D,D-CARBOXYPEPTIDASE (Enterococcusfaecalis) |
PF02557(VanY) | 5 | PHE A 124ILE A 122ASN A 65VAL A 68LEU A 115 | NoneNoneGOL A 315 (-4.1A)NoneNone | 1.09A | 4fr0A-4f78A:undetectable | 4fr0A-4f78A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn5 | ELONGATION FACTOR G1 (Pseudomonasaeruginosa) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF03764(EFG_IV)PF14492(EFG_II) | 5 | GLY A 14ASP A 107ILE A 138VAL A 282LEU A 279 | None | 1.12A | 4fr0A-4fn5A:2.0 | 4fr0A-4fn5A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn7 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Mycobacteriumtuberculosis) |
PF00378(ECH_1) | 5 | GLY A 81LEU A 26GLN A 31ILE A 144LEU A 89 | None | 1.12A | 4fr0A-4fn7A:undetectable | 4fr0A-4fn7A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htf | S-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Escherichiacoli) |
PF13847(Methyltransf_31) | 5 | GLY B 56GLY B 53LEU B 117ILE B 60GLU B 64 | NoneSAM B 301 (-3.8A)NoneNoneNone | 1.12A | 4fr0A-4htfB:14.9 | 4fr0A-4htfB:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ic5 | PROTEASE DO-LIKE 5,CHLOROPLASTIC (Arabidopsisthaliana) |
PF13365(Trypsin_2) | 5 | GLY A 133GLY A 268ILE A 142ASN A 223VAL A 103 | None | 1.07A | 4fr0A-4ic5A:undetectable | 4fr0A-4ic5A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifr | 2-AMINO-3-CARBOXYMUCONATE 6-SEMIALDEHYDEDECARBOXYLASE (Pseudomonasfluorescens) |
PF04909(Amidohydro_2) | 5 | GLY A 230ILE A 224ASN A 148VAL A 176LEU A 175 | None | 1.04A | 4fr0A-4ifrA:undetectable | 4fr0A-4ifrA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx2 | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
no annotation | 6 | GLY A 133MET A 137LEU A 257ASN A 191VAL A 190LEU A 187 | None | 1.42A | 4fr0A-4jx2A:undetectable | 4fr0A-4jx2A:20.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 9 | GLY A 91ASP A 97MET A 116LEU A 117PHE A 150ILE A 151GLU A 152VAL A 175LEU A 178 | CA A 401 (-4.4A)NoneNoneNoneNoneNoneNoneNoneNone | 1.04A | 4fr0A-4kw7A:46.9 | 4fr0A-4kw7A:98.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 8 | GLY A 91GLY A 93ASP A 97MET A 116LEU A 117GLN A 120ILE A 151GLU A 152 | CA A 401 (-4.4A)NoneNoneNoneNoneNoneNoneNone | 0.75A | 4fr0A-4kw7A:46.9 | 4fr0A-4kw7A:98.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 8 | GLY A 91GLY A 93ASP A 97MET A 116LEU A 117PHE A 150ILE A 151GLU A 152 | CA A 401 (-4.4A)NoneNoneNoneNoneNoneNoneNone | 0.73A | 4fr0A-4kw7A:46.9 | 4fr0A-4kw7A:98.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 7 | GLY A 91MET A 116LEU A 117GLN A 120ILE A 151GLU A 152ASN A 173 | CA A 401 (-4.4A)NoneNoneNoneNoneNoneNone | 0.82A | 4fr0A-4kw7A:46.9 | 4fr0A-4kw7A:98.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4kw7 | ARSENICMETHYLTRANSFERASE (Cyanidioschyzonsp. 5508) |
PF13847(Methyltransf_31) | 9 | GLY A 91MET A 116LEU A 117PHE A 150ILE A 151GLU A 152ASN A 173VAL A 175LEU A 178 | CA A 401 (-4.4A)NoneNoneNoneNoneNoneNoneNoneNone | 0.92A | 4fr0A-4kw7A:46.9 | 4fr0A-4kw7A:98.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lsw | D-2-HYDROXYACIDDEHYDROGENSASEPROTEIN (Ketogulonicigeniumvulgare) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | GLY A 108MET A 112LEU A 113PHE A 200VAL A 160 | None | 1.09A | 4fr0A-4lswA:5.4 | 4fr0A-4lswA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4miv | N-SULPHOGLUCOSAMINESULPHOHYDROLASE (Homo sapiens) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | GLY A 281ASP A 32GLU A 447ASN A 274LEU A 285 | NoneFGP A 70 (-3.0A)None CA A 601 (-3.0A)None | 1.10A | 4fr0A-4mivA:undetectable | 4fr0A-4mivA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n02 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Streptococcuspneumoniae) |
PF01070(FMN_dh) | 5 | GLY A 68GLY A 64ASP A 101ILE A 71GLU A 282 | None | 1.15A | 4fr0A-4n02A:undetectable | 4fr0A-4n02A:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9z | HUMAN PROTEIN KINASEC THETA (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 5 | ASP A 508LEU A 569ILE A 518ASN A 509LEU A 492 | NoneNoneNonePZW A 801 (-4.4A)None | 1.14A | 4fr0A-4q9zA:undetectable | 4fr0A-4q9zA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wfi | CUTINASE (Saccharomonosporaviridis) |
PF03403(PAF-AH_p_II) | 5 | GLY A 98LEU A 272ILE A 126ASN A 168LEU A 150 | None | 1.14A | 4fr0A-4wfiA:2.4 | 4fr0A-4wfiA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyr | ACETYL-COAACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | GLY A 291GLY A 282MET A 288GLN A 383LEU A 377 | None | 1.10A | 4fr0A-4wyrA:undetectable | 4fr0A-4wyrA:24.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b16 | RIBONUCLEASE3,DROSHA,RIBONUCLEASE3,DROSHA,RIBONUCLEASE 3 (Homo sapiens) |
PF00035(dsrm)PF00636(Ribonuclease_3)PF14622(Ribonucleas_3_3) | 5 | GLY A 921GLN A 858ILE A 656ASN A 919LEU A 659 | None | 1.10A | 4fr0A-5b16A:undetectable | 4fr0A-5b16A:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c22 | CHROMOSOMALHEMOLYSIN D (Escherichiacoli) |
PF13437(HlyD_3) | 5 | GLY A 115MET A 357LEU A 341ILE A 359VAL A 118 | None | 1.15A | 4fr0A-5c22A:undetectable | 4fr0A-5c22A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c65 | SOLUTE CARRIERFAMILY 2,FACILITATED GLUCOSETRANSPORTER MEMBER 3 (Homo sapiens) |
PF00083(Sugar_tr) | 5 | GLY A 152GLY A 155GLU A 452VAL A 326LEU A 334 | None | 1.10A | 4fr0A-5c65A:undetectable | 4fr0A-5c65A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djq | CBB3-TYPE CYTOCHROMEC OXIDASE SUBUNITCCON1PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasstutzeri;Pseudomonasstutzeri) |
PF00115(COX1)no annotation | 5 | ASP A 304PHE N 27ILE N 28VAL A 311LEU A 314 | None | 0.82A | 4fr0A-5djqA:undetectable | 4fr0A-5djqA:24.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5evj | ARSENITEMETHYLTRANSFERASE (Chlamydomonasreinhardtii) |
PF13847(Methyltransf_31) | 10 | GLY A 91GLY A 93ASP A 97MET A 116GLN A 120ILE A 150GLU A 151ASN A 169VAL A 171LEU A 174 | None | 0.57A | 4fr0A-5evjA:39.4 | 4fr0A-5evjA:45.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1m | PHOSPHORYLATEDPROTEIN PHOSPHATASE (Staphylococcusaureus) |
PF13672(PP2C_2) | 5 | GLY A 38GLY A 40ASP A 233MET A 99ASN A 234 | MN A 302 (-3.9A) MN A 302 ( 4.7A) MN A 301 (-2.4A)NoneNone | 1.15A | 4fr0A-5f1mA:undetectable | 4fr0A-5f1mA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fdn | PHOSPHOENOLPYRUVATECARBOXYLASE 3 (Arabidopsisthaliana) |
PF00311(PEPcase) | 5 | GLY A 968LEU A 964PHE A 776ILE A 775VAL A 787 | None | 1.08A | 4fr0A-5fdnA:undetectable | 4fr0A-5fdnA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gad | SIGNAL RECOGNITIONPARTICLE RECEPTORFTSY (Escherichiacoli) |
PF00238(Ribosomal_L14) | 5 | GLY l 300GLY l 385ASP l 382LEU l 387VAL l 304 | NoneGNP l1400 ( 3.3A) MG l1401 ( 4.1A)NoneGNP l1400 ( 4.1A) | 0.97A | 4fr0A-5gadl:undetectable | 4fr0A-5gadl:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jz8 | ASPARTYL/ASPARAGINYLBETA-HYDROXYLASE (Homo sapiens) |
PF05118(Asp_Arg_Hydrox)PF13181(TPR_8)PF13432(TPR_16) | 5 | GLY A 461GLY A 463ASP A 469ASN A 472VAL A 476 | None | 0.98A | 4fr0A-5jz8A:undetectable | 4fr0A-5jz8A:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3r | SIGNAL RECOGNITIONPARTICLE 54 KDAPROTEIN,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | GLY A 183GLY A 268ASP A 265LEU A 270VAL A 187 | NoneGCP A 401 (-3.4A) MG A 402 (-3.9A)GCP B 401 ( 4.9A)GCP A 401 (-4.2A) | 1.05A | 4fr0A-5l3rA:2.3 | 4fr0A-5l3rA:24.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5naq | BETA-GALACTOSIDASE (Lactobacillusplantarum) |
PF00232(Glyco_hydro_1) | 5 | GLY A 16GLN A 78PHE A 153ILE A 115ASN A 164 | None | 1.14A | 4fr0A-5naqA:undetectable | 4fr0A-5naqA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd4 | TUBULIN ALPHA CHAIN (Bos taurus) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | GLY A 106GLY A 148ILE A 110GLU A 97ASN A 101 | NoneNoneNoneNoneGTP A 500 (-3.3A) | 1.12A | 4fr0A-5nd4A:3.2 | 4fr0A-5nd4A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ogx | CYTOCHROME P450REDUCTASE (Amycolatopsismethanolica) |
no annotation | 5 | GLY A 41GLY A 38GLN A 76ASN A 33LEU A 45 | FES A 402 (-3.7A)FES A 402 (-3.4A)NoneNone NA A 403 ( 4.9A) | 1.09A | 4fr0A-5ogxA:5.5 | 4fr0A-5ogxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thz | CURJ (Mooreaproducens) |
no annotation | 5 | GLY B 205GLY B 207ILE B 204ASN B 277VAL B 278 | SAH B 501 (-3.5A)SAH B 501 (-3.3A)NoneGOL B 502 (-4.3A)SAH B 501 (-4.1A) | 1.03A | 4fr0A-5thzB:14.5 | 4fr0A-5thzB:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u0l | N-SUCCINYLGLUTAMATE5-SEMIALDEHYDEDEHYDROGENASE (Marinobacterhydrocarbonoclasticus) |
PF00171(Aldedh) | 5 | LEU A 212ILE A 10ASN A 37VAL A 8LEU A 201 | None | 0.97A | 4fr0A-5u0lA:undetectable | 4fr0A-5u0lA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ubc | PROTEIN TOC75-3,CHLOROPLASTIC (Arabidopsisthaliana) |
no annotation | 5 | GLY A 409ILE A 366ASN A 428VAL A 441LEU A 369 | None | 0.92A | 4fr0A-5ubcA:undetectable | 4fr0A-5ubcA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uvn | PARAQUAT-INDUCIBLEPROTEIN B (Escherichiacoli) |
PF02470(MlaD) | 5 | GLY A 370LEU A 368ILE A 339VAL A 305LEU A 312 | None | 1.12A | 4fr0A-5uvnA:undetectable | 4fr0A-5uvnA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0a | GLUCANASE (Trichodermaharzianum) |
no annotation | 5 | GLY A 140LEU A 330ILE A 319ASN A 352LEU A 134 | GLY A 140 ( 0.0A)LEU A 330 ( 0.5A)ILE A 319 ( 0.7A)ASN A 352 ( 0.6A)LEU A 134 ( 0.6A) | 1.05A | 4fr0A-5w0aA:undetectable | 4fr0A-5w0aA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x9y | DNA MISMATCH REPAIRPROTEIN MUTL (Aquifexaeolicus) |
no annotation | 5 | ASP C 18PHE C 182ILE C 39VAL C 163LEU C 164 | None | 1.15A | 4fr0A-5x9yC:undetectable | 4fr0A-5x9yC:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgs | RCC1-LIKE GEXCHANGINGFACTOR-LIKE PROTEIN (Homo sapiens) |
PF00415(RCC1)PF13540(RCC1_2) | 5 | GLY A 302LEU A 304ASN A 284VAL A 283LEU A 280 | None | 1.12A | 4fr0A-5xgsA:undetectable | 4fr0A-5xgsA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 5 | GLY A 449LEU A 403ILE A 515ASN A 476VAL A 470 | None | 1.04A | 4fr0A-5zl9A:undetectable | 4fr0A-5zl9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fae | IQ MOTIF AND SEC7DOMAIN-CONTAININGPROTEIN 2ADP-RIBOSYLATIONFACTOR 1 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 5 | GLY B 50ASP B 67ILE A 538VAL A 502LEU A 505 | None | 0.89A | 4fr0A-6faeB:undetectable | 4fr0A-6faeB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fi2 | VEXL (Achromobacterdenitrificans) |
no annotation | 5 | GLY A 123LEU A 74ILE A 139ASN A 151LEU A 134 | None | 1.10A | 4fr0A-6fi2A:undetectable | 4fr0A-6fi2A:undetectable |