SIMILAR PATTERNS OF AMINO ACIDS FOR 4FP9_A_SAMA401_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1br2 MYOSIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		3 ASP A 618
ARG A 354
ASP A 623
 None
 0.86A 4fp9A-1br2A:
undetectable		 4fp9A-1br2A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ASP A 614
ARG A 590
ASP A 558
 None
 0.77A 4fp9A-1c30A:
2.2		 4fp9A-1c30A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ciy CRYIA(A)

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 ASP A 599
ARG A 600
ASP A 497
 None
 0.83A 4fp9A-1ciyA:
undetectable		 4fp9A-1ciyA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d0n HORSE PLASMA
GELSOLIN

(Equus caballus) 		PF00626
(Gelsolin) 		3 ASP A 675
ARG A 641
ASP A 678
 None
 0.75A 4fp9A-1d0nA:
undetectable		 4fp9A-1d0nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d7w MYELOPEROXIDASE
MYELOPEROXIDASE

(Homo sapiens;
Homo sapiens) 		PF03098
(An_peroxidase)
PF03098
(An_peroxidase) 		3 ASP C 400
ARG C 403
ASP A  74
 SO4  A1602 (-4.7A)
None
None
 0.65A 4fp9A-1d7wC:
undetectable		 4fp9A-1d7wC:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d9s CYCLIN-DEPENDENT
KINASE 4 INHIBITOR B

(Mus musculus) 		PF12796
(Ank_2) 		3 ASP A  78
ARG A  81
ASP A  68
 None
 0.75A 4fp9A-1d9sA:
undetectable		 4fp9A-1d9sA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fot CAMP-DEPENDENT
PROTEIN KINASE TYPE
1

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		3 ASP A 396
ARG A 395
ASP A 134
 None
 0.65A 4fp9A-1fotA:
undetectable		 4fp9A-1fotA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzv NITRITE REDUCTASE

(Pseudomonas
aeruginosa) 		PF02239
(Cytochrom_D1)
PF13442
(Cytochrome_CBB3) 		3 ASP A 157
ARG A 156
ASP A 503
 None
 0.85A 4fp9A-1hzvA:
undetectable		 4fp9A-1hzvA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1io1 PHASE 1 FLAGELLIN

(Salmonella
enterica) 		PF00669
(Flagellin_N)
PF00700
(Flagellin_C)
PF08884
(Flagellin_D3) 		3 ASP A 419
ARG A 422
ASP A 412
 None
 0.81A 4fp9A-1io1A:
undetectable		 4fp9A-1io1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jy1 TYROSYL-DNA
PHOSPHODIESTERASE

(Homo sapiens) 		PF06087
(Tyr-DNA_phospho) 		3 ASP A 187
ARG A 170
ASP A 156
 None
 0.81A 4fp9A-1jy1A:
undetectable		 4fp9A-1jy1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdf 2,3-DIHYDROXYBENZOAT
E-AMP LIGASE

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ASP A 205
ARG A  17
ASP A  29
 None
 0.75A 4fp9A-1mdfA:
undetectable		 4fp9A-1mdfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfg D-HYDANTOINASE

(Ralstonia
pickettii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		3 ASP A 193
ARG A 331
ASP A 186
 None
 0.61A 4fp9A-1nfgA:
undetectable		 4fp9A-1nfgA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC

(Klebsiella
pneumoniae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 ASP A 304
ARG A 159
ASP A 323
 None
 0.62A 4fp9A-1ozhA:
undetectable		 4fp9A-1ozhA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0z ACLACINOMYCIN
METHYLESTERASE

(Streptomyces
purpurascens) 		PF00561
(Abhydrolase_1) 		3 ASP A  94
ARG A  95
ASP A  89
 None
 0.82A 4fp9A-1q0zA:
undetectable		 4fp9A-1q0zA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ASP A 357
ARG A 361
ASP A 117
 None
 0.66A 4fp9A-1qk1A:
undetectable		 4fp9A-1qk1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryt RUBRERYTHRIN

(Desulfovibrio
vulgaris) 		PF02915
(Rubrerythrin) 		3 ASP A  51
ARG A  24
ASP A  44
 None
 0.83A 4fp9A-1rytA:
undetectable		 4fp9A-1rytA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2

(Homo sapiens) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		3 ASP A  43
ARG A 225
ASP A  53
 None
 0.80A 4fp9A-1s9cA:
undetectable		 4fp9A-1s9cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb8 WBPP

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		3 ASP A  78
ARG A  80
ASP A  47
 NAD  A 342 (-3.2A)
None
NAD  A 342 (-2.8A)
 0.78A 4fp9A-1sb8A:
7.0		 4fp9A-1sb8A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sus CAFFEOYL-COA
O-METHYLTRANSFERASE

(Medicago sativa) 		PF01596
(Methyltransf_3) 		3 ASP A 214
ARG A 213
ASP A 167
 None
 0.78A 4fp9A-1susA:
10.6		 4fp9A-1susA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6t PUTATIVE PROTEIN

(Aquifex
aeolicus) 		PF01751
(Toprim) 		3 ASP 1  53
ARG 1  50
ASP 1  45
 None
 0.80A 4fp9A-1t6t1:
undetectable		 4fp9A-1t6t1:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2q LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE

(Mycobacterium
tuberculosis) 		PF01451
(LMWPc) 		3 ASP A 114
ARG A 116
ASP A 151
 None
 0.80A 4fp9A-1u2qA:
undetectable		 4fp9A-1u2qA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u8v GAMMA-AMINOBUTYRATE
METABOLISM
DEHYDRATASE/ISOMERAS
E

(Clostridium
aminobutyricum) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 ASP A 167
ARG A 183
ASP A 151
 None
 0.79A 4fp9A-1u8vA:
undetectable		 4fp9A-1u8vA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcc DNA TOPOISOMERASE I

(Vaccinia virus) 		PF09266
(VirDNA-topo-I_N) 		3 ASP A  63
ARG A  67
ASP A  42
 None
 0.63A 4fp9A-1vccA:
undetectable		 4fp9A-1vccA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 ASP A 626
ARG A 627
ASP A 507
 None
 0.83A 4fp9A-1w99A:
undetectable		 4fp9A-1w99A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1n 4-ALPHA-GLUCANOTRANS
FERASE

(Solanum
tuberosum) 		PF02446
(Glyco_hydro_77) 		3 ASP A 369
ARG A 381
ASP A 321
 None
None
GOL  A1001 (-4.9A)
 0.85A 4fp9A-1x1nA:
undetectable		 4fp9A-1x1nA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x25 HYPOTHETICAL UPF0076
PROTEIN ST0811

(Sulfurisphaera
tokodaii) 		PF01042
(Ribonuc_L-PSP) 		3 ASP A  35
ARG A  37
ASP A  55
 None
 0.74A 4fp9A-1x25A:
undetectable		 4fp9A-1x25A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y30 HYPOTHETICAL PROTEIN
RV1155

(Mycobacterium
tuberculosis) 		PF01243
(Putative_PNPOx) 		3 ASP A  28
ARG A  30
ASP A  64
 None
 0.83A 4fp9A-1y30A:
undetectable		 4fp9A-1y30A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E

(Pyrococcus
abyssi) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD) 		3 ASP C 181
ARG C 179
ASP C 164
 None
 0.78A 4fp9A-1zq1C:
undetectable		 4fp9A-1zq1C:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a4m TRYPTOPHANYL-TRNA
SYNTHETASE II

(Deinococcus
radiodurans) 		PF00579
(tRNA-synt_1b) 		3 ASP A 243
ARG A 254
ASP A 251
 None
 0.73A 4fp9A-2a4mA:
undetectable		 4fp9A-2a4mA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9e NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 258
ARG A 263
ASP A 285
 SAM  A1201 (-2.6A)
SAM  A1201 (-3.9A)
SAM  A1201 (-3.6A)
 0.71A 4fp9A-2b9eA:
23.4		 4fp9A-2b9eA:
25.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bco SUCCINYLGLUTAMATE
DESUCCINYLASE

(Vibrio
parahaemolyticus) 		PF04952
(AstE_AspA) 		3 ASP A 274
ARG A 315
ASP A 296
 None
 0.85A 4fp9A-2bcoA:
undetectable		 4fp9A-2bcoA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E

(Methanothermobacter
thermautotrophicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD) 		3 ASP C 176
ARG C 174
ASP C 159
 None
 0.76A 4fp9A-2d6fC:
undetectable		 4fp9A-2d6fC:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb5 2-OXO-HEPT-3-ENE-1,7
-DIOATE HYDRATASE

(Escherichia
coli) 		PF01557
(FAA_hydrolase) 		3 ASP A 184
ARG A 186
ASP A 181
 None
 0.80A 4fp9A-2eb5A:
undetectable		 4fp9A-2eb5A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsn PHOSPHODIESTERASE-NU
CLEOTIDE
PYROPHOSPHATASE

(Xanthomonas
citri) 		PF01663
(Phosphodiest) 		3 ASP A 244
ARG A 188
ASP A 194
 None
 0.83A 4fp9A-2gsnA:
undetectable		 4fp9A-2gsnA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iny HEXON PROTEIN

(Fowl
aviadenovirus A) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 ASP A 898
ARG A 688
ASP A 499
 None
 0.86A 4fp9A-2inyA:
undetectable		 4fp9A-2inyA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 ASP A 205
ARG A 557
ASP A 208
 None
 0.86A 4fp9A-2iujA:
undetectable		 4fp9A-2iujA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 ASP A 204
ARG A 206
ASP A 225
 MGD  A 812 (-2.7A)
MGD  A 812 (-3.9A)
MGD  A 812 (-3.4A)
 0.56A 4fp9A-2jirA:
undetectable		 4fp9A-2jirA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jsz PROBABLE THIOL
PEROXIDASE

(Bacillus
subtilis) 		PF08534
(Redoxin) 		3 ASP A  61
ARG A  65
ASP A  56
 None
 0.71A 4fp9A-2jszA:
undetectable		 4fp9A-2jszA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nqa CALPAIN 8

(Homo sapiens) 		PF00648
(Peptidase_C2) 		3 ASP A 156
ARG A  77
ASP A 130
 None
 0.65A 4fp9A-2nqaA:
undetectable		 4fp9A-2nqaA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1f URIDINE
5'-MONOPHOSPHATE
SYNTHASE

(Homo sapiens) 		PF00215
(OMPdecase) 		3 ASP A  96
ARG A 124
ASP A  70
 None
None
GOL  A2000 (-2.9A)
 0.86A 4fp9A-2p1fA:
undetectable		 4fp9A-2p1fA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pxx UNCHARACTERIZED
PROTEIN MGC2408

(Homo sapiens) 		PF08241
(Methyltransf_11) 		3 ASP A 113
ARG A 115
ASP A  88
 SAH  A 301 (-3.1A)
None
SAH  A 301 (-2.9A)
 0.62A 4fp9A-2pxxA:
10.3		 4fp9A-2pxxA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyb NEUTROPHIL
ACTIVATING PROTEIN

(Borreliella
burgdorferi) 		PF00210
(Ferritin) 		3 ASP A 132
ARG A  70
ASP A 128
 None
 0.82A 4fp9A-2pybA:
undetectable		 4fp9A-2pybA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qcm URIDINE
5'-MONOPHOSPHATE
SYNTHASE (UMP
SYNTHASE)

(Homo sapiens) 		PF00215
(OMPdecase) 		3 ASP A 285
ARG A 313
ASP A 259
 None
None
JW5  A 482 (-2.9A)
 0.86A 4fp9A-2qcmA:
undetectable		 4fp9A-2qcmA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyk CYCLIC AMP-SPECIFIC
PHOSPHODIESTERASE
HSPDE4A10

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 616
ARG A 615
ASP A 609
 None
 0.85A 4fp9A-2qykA:
undetectable		 4fp9A-2qykA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vbf BRANCHED-CHAIN
ALPHA-KETOACID
DECARBOXYLASE

(Lactococcus
lactis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 ASP A 319
ARG A 321
ASP A 306
 ASP  A 319 ( 0.6A)
ARG  A 321 ( 0.6A)
ASP  A 306 ( 0.6A)
 0.82A 4fp9A-2vbfA:
undetectable		 4fp9A-2vbfA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu8 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Mycobacterium
tuberculosis) 		PF00342
(PGI) 		3 ASP A 134
ARG A 137
ASP A 127
 None
 0.87A 4fp9A-2wu8A:
undetectable		 4fp9A-2wu8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ybu ACIDIC MAMMALIAN
CHITINASE

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		3 ASP A 205
ARG A 163
ASP A 133
 None
 0.78A 4fp9A-2ybuA:
undetectable		 4fp9A-2ybuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn3 PUTATIVE INNER
MEMBRANE PROTEIN

(Salmonella
enterica) 		PF12245
(Big_3_2) 		3 ASP A5183
ARG A5182
ASP A5170
 None
 0.87A 4fp9A-2yn3A:
undetectable		 4fp9A-2yn3A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z02 PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Methanocaldococcus
jannaschii) 		PF01259
(SAICAR_synt) 		3 ASP A 217
ARG A 206
ASP A 214
 None
SO4  A 512 (-3.1A)
None
 0.78A 4fp9A-2z02A:
undetectable		 4fp9A-2z02A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyl POSSIBLE
OXIDOREDUCTASE

(Mycobacterium
tuberculosis) 		PF00355
(Rieske) 		3 ASP A 120
ARG A 122
ASP A  59
 None
 0.76A 4fp9A-2zylA:
undetectable		 4fp9A-2zylA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay0 UNCHARACTERIZED
PROTEIN MJ0883

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		3 ASP A 251
ARG A 253
ASP A 223
 ADN  A 401 (-3.8A)
None
ADN  A 401 (-2.6A)
 0.85A 4fp9A-3ay0A:
11.5		 4fp9A-3ay0A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1b CARBONIC ANHYDRASE 1

(Chlamydomonas
reinhardtii) 		PF00194
(Carb_anhydrase) 		3 ASP A 150
ARG A 147
ASP A 142
 None
 0.82A 4fp9A-3b1bA:
undetectable		 4fp9A-3b1bA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF01256
(Carb_kinase) 		3 ASP A 112
ARG A 137
ASP A 105
 None
 0.81A 4fp9A-3bgkA:
4.5		 4fp9A-3bgkA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh3 ACETOACETATE
DECARBOXYLASE

(Chromobacterium
violaceum) 		PF06314
(ADC) 		3 ASP A 135
ARG A 140
ASP A 100
 None
 0.82A 4fp9A-3bh3A:
undetectable		 4fp9A-3bh3A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bhw UNCHARACTERIZED
PROTEIN

(Magnetospirillum
magneticum) 		PF08849
(DUF1819) 		3 ASP A 109
ARG A 112
ASP A 104
 None
 0.67A 4fp9A-3bhwA:
undetectable		 4fp9A-3bhwA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxw CHITINASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		no annotation 3 ASP B 369
ARG B  26
ASP B  52
 None
 0.81A 4fp9A-3bxwB:
undetectable		 4fp9A-3bxwB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d0k PUTATIVE
POLY(3-HYDROXYBUTYRA
TE) DEPOLYMERASE
LPQC

(Bordetella
parapertussis) 		no annotation 3 ASP A  28
ARG A 123
ASP A  34
 None
 0.85A 4fp9A-3d0kA:
undetectable		 4fp9A-3d0kA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dah RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE

(Burkholderia
pseudomallei) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		3 ASP A 101
ARG A 102
ASP A 136
 None
AMP  A 401 ( 4.7A)
None
 0.67A 4fp9A-3dahA:
undetectable		 4fp9A-3dahA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eno PUTATIVE
O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Thermoplasma
acidophilum) 		PF00814
(Peptidase_M22) 		3 ASP A 318
ARG A 316
ASP A 321
 None
 0.86A 4fp9A-3enoA:
undetectable		 4fp9A-3enoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 ASP A 565
ARG A 595
ASP A 584
 None
 0.79A 4fp9A-3gwjA:
undetectable		 4fp9A-3gwjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE

(Shewanella
putrefaciens) 		PF12680
(SnoaL_2) 		3 ASP A  47
ARG A  46
ASP A 128
 None
 0.59A 4fp9A-3gzbA:
undetectable		 4fp9A-3gzbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 15

(Thermus
thermophilus) 		PF11497
(NADH_Oxid_Nqo15) 		3 ASP 7  39
ARG 7  75
ASP 7  36
 None
 0.80A 4fp9A-3i9v7:
undetectable		 4fp9A-3i9v7:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jci CAPSID PROTEIN

(Porcine
circovirus 2) 		PF02443
(Circo_capsid) 		3 ASP A 127
ARG A  73
ASP A 168
 None
 0.72A 4fp9A-3jciA:
undetectable		 4fp9A-3jciA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khs PURINE NUCLEOSIDE
PHOSPHORYLASE

(Singapore
grouper
iridovirus) 		PF01048
(PNP_UDP_1) 		3 ASP A 125
ARG A 122
ASP A 212
 None
 0.87A 4fp9A-3khsA:
undetectable		 4fp9A-3khsA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lme POSSIBLE TRANSLATION
INITIATION INHIBITOR

(Rhodopseudomonas
palustris) 		PF01042
(Ribonuc_L-PSP) 		3 ASP A  83
ARG A  79
ASP A  64
 None
 0.77A 4fp9A-3lmeA:
undetectable		 4fp9A-3lmeA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lq1 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE

(Listeria
monocytogenes) 		PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
PF16582
(TPP_enzyme_M_2) 		3 ASP A 271
ARG A 371
ASP A 274
 None
 0.78A 4fp9A-3lq1A:
2.2		 4fp9A-3lq1A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvq SEMAPHORIN-7A

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI)
PF13895
(Ig_2) 		3 ASP A 343
ARG A 347
ASP A 238
 None
 0.82A 4fp9A-3nvqA:
undetectable		 4fp9A-3nvqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obi FORMYLTETRAHYDROFOLA
TE DEFORMYLASE

(Rhodopseudomonas
palustris) 		PF00551
(Formyl_trans_N) 		3 ASP A 272
ARG A  85
ASP A 113
 None
 0.84A 4fp9A-3obiA:
2.5		 4fp9A-3obiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oov METHYL-ACCEPTING
CHEMOTAXIS PROTEIN,
PUTATIVE

(Geobacter
sulfurreducens) 		PF13185
(GAF_2) 		3 ASP A 130
ARG A  33
ASP A 142
 GOL  A 167 (-3.6A)
None
None
 0.74A 4fp9A-3oovA:
undetectable		 4fp9A-3oovA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3plt SPHINGOLIPID LONG
CHAIN
BASE-RESPONSIVE
PROTEIN LSP1

(Saccharomyces
cerevisiae) 		PF13805
(Pil1) 		3 ASP A 123
ARG A 126
ASP A 116
 None
 0.73A 4fp9A-3pltA:
undetectable		 4fp9A-3pltA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6t 43.2 KDA SALIVARY
PROTEIN

(Lutzomyia
longipalpis) 		PF03022
(MRJP) 		3 ASP A 332
ARG A 364
ASP A 283
 None
 0.81A 4fp9A-3q6tA:
undetectable		 4fp9A-3q6tA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0r PORCINE CIRCOVIRUS 2
(PCV2) CAPSID
PROTEIN

(Porcine
circovirus 2) 		PF02443
(Circo_capsid) 		3 ASP A 122
ARG A  68
ASP A 163
 None
 0.73A 4fp9A-3r0rA:
undetectable		 4fp9A-3r0rA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		3 ASP A 405
ARG A 466
ASP A 385
 None
 0.85A 4fp9A-3sfzA:
undetectable		 4fp9A-3sfzA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wa1 BINB PROTEIN

(Lysinibacillus
sphaericus) 		PF05431
(Toxin_10) 		3 ASP A 100
ARG A  99
ASP A  80
 None
 0.72A 4fp9A-3wa1A:
undetectable		 4fp9A-3wa1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		3 ASP A 260
ARG A 257
ASP A 280
 None
 0.61A 4fp9A-3wfzA:
undetectable		 4fp9A-3wfzA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif HEXON PROTEIN

(Bovine
mastadenovirus
B) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 ASP A 108
ARG A 516
ASP A 519
 None
 0.80A 4fp9A-3zifA:
undetectable		 4fp9A-3zifA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c4a PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Mus musculus) 		PF06325
(PrmA) 		3 ASP A 554
ARG A 559
ASP A 547
 None
 0.75A 4fp9A-4c4aA:
7.0		 4fp9A-4c4aA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chd POLYMERASE ACIDIC
PROTEIN

(Thogoto
thogotovirus) 		no annotation 3 ASP A 666
ARG A 617
ASP A 656
 None
 0.73A 4fp9A-4chdA:
undetectable		 4fp9A-4chdA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 146
ARG A 193
ASP A 141
 None
 0.73A 4fp9A-4e4uA:
undetectable		 4fp9A-4e4uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe2 PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Streptococcus
pneumoniae) 		PF01259
(SAICAR_synt) 		3 ASP A 209
ARG A 199
ASP A 202
 None
AIR  A 301 (-3.1A)
None
 0.81A 4fp9A-4fe2A:
undetectable		 4fp9A-4fe2A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj4 UNCHARACTERIZED
PROTEIN

(Halobacterium
salinarum) 		PF07920
(DUF1684) 		3 ASP A 187
ARG A 185
ASP A  47
 None
 0.58A 4fp9A-4fj4A:
undetectable		 4fp9A-4fj4A:
19.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 204
ARG A 209
ASP A 237
 SAM  A 401 (-2.9A)
SAM  A 401 (-3.6A)
SAM  A 401 (-3.5A)
 0.18A 4fp9A-4fzvA:
59.1		 4fp9A-4fzvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmq PUTATIVE RIBOSOME
ASSOCIATED PROTEIN

(Chaetomium
thermophilum) 		PF16717
(RAC_head) 		3 ASP A 392
ARG A 365
ASP A 385
 None
 0.75A 4fp9A-4gmqA:
undetectable		 4fp9A-4gmqA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gn8 REGUCALCIN

(Mus musculus) 		PF08450
(SGL) 		3 ASP A 151
ARG A 129
ASP A 148
 None
 0.77A 4fp9A-4gn8A:
undetectable		 4fp9A-4gn8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0f LAMININ-BINDING
SURFACE PROTEIN

(Streptococcus
agalactiae) 		PF01297
(ZnuA) 		3 ASP A  55
ARG A  57
ASP A  52
 None
 0.87A 4fp9A-4h0fA:
undetectable		 4fp9A-4h0fA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inj LMO1638 PROTEIN

(Listeria
monocytogenes) 		PF02016
(Peptidase_S66) 		3 ASP A 241
ARG A 240
ASP A 230
 MG  A 402 ( 4.5A)
None
None
 0.74A 4fp9A-4injA:
undetectable		 4fp9A-4injA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jiw PUTATIVE
UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF05488
(PAAR_motif) 		3 ASP D  77
ARG D  74
ASP D  41
 None
 0.68A 4fp9A-4jiwD:
undetectable		 4fp9A-4jiwD:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw7 ARSENIC
METHYLTRANSFERASE

(Cyanidioschyzon
sp. 5508) 		PF13847
(Methyltransf_31) 		3 ASP A  97
ARG A  96
ASP A 115
 None
 0.81A 4fp9A-4kw7A:
8.7		 4fp9A-4kw7A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN

(Caulobacter
vibrioides) 		PF04390
(LptE) 		3 ASP A 125
ARG A  93
ASP A 139
 None
 0.74A 4fp9A-4kwyA:
undetectable		 4fp9A-4kwyA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg3 UNCHARACTERIZED
PROTEIN

(Desulfovibrio
piger) 		PF16175
(DUF4875) 		3 ASP A 176
ARG A 178
ASP A 172
 None
 0.73A 4fp9A-4lg3A:
undetectable		 4fp9A-4lg3A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lj2 CHORISMATE SYNTHASE

(Acinetobacter
baumannii) 		PF01264
(Chorismate_synt) 		3 ASP A 342
ARG A 346
ASP A  28
 None
 0.82A 4fp9A-4lj2A:
undetectable		 4fp9A-4lj2A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m6r METHYLTHIORIBULOSE-1
-PHOSPHATE
DEHYDRATASE

(Homo sapiens) 		PF00596
(Aldolase_II) 		3 ASP A 157
ARG A 154
ASP A 186
 None
 0.66A 4fp9A-4m6rA:
undetectable		 4fp9A-4m6rA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mjd KETOSTEROID
ISOMERASE FOLD
PROTEIN HMUK_0747

(Halomicrobium
mukohataei) 		PF12680
(SnoaL_2) 		3 ASP A  33
ARG A 104
ASP A  36
 None
 0.83A 4fp9A-4mjdA:
undetectable		 4fp9A-4mjdA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrp ABC TRANSPORTER
RELATED PROTEIN

(Novosphingobium
aromaticivorans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 ASP A 111
ARG A 107
ASP A  31
 None
 0.55A 4fp9A-4mrpA:
undetectable		 4fp9A-4mrpA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mur D,D-DIPEPTIDASE/D,D-
CARBOXYPEPTIDASE

(Enterococcus
gallinarum) 		PF02557
(VanY) 		3 ASP A  29
ARG A  56
ASP A  31
 None
 0.85A 4fp9A-4murA:
undetectable		 4fp9A-4murA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbv 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE PUTATIVE
SHORT-CHAIN
DEHYDROGENASES/REDUC
TASES (SDR) FAMILY
PROTEIN

(Cupriavidus
taiwanensis) 		PF13561
(adh_short_C2) 		3 ASP A  36
ARG A  41
ASP A  62
 None
 0.87A 4fp9A-4nbvA:
7.2		 4fp9A-4nbvA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p8r GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE,
CYTOSOLIC

(Trypanosoma
brucei) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ASP A 276
ARG A 296
ASP A 258
 None
 0.86A 4fp9A-4p8rA:
4.0		 4fp9A-4p8rA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4py4 POLY [ADP-RIBOSE]
POLYMERASE 14

(Homo sapiens) 		PF00644
(PARP) 		3 ASP A1731
ARG A1735
ASP A1725
 None
 0.81A 4fp9A-4py4A:
undetectable		 4fp9A-4py4A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ASP A 263
ARG A 267
ASP A 298
 None
 0.82A 4fp9A-4q73A:
4.0		 4fp9A-4q73A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		3 ASP A 482
ARG A 465
ASP A 460
 None
 0.74A 4fp9A-4r4zA:
undetectable		 4fp9A-4r4zA:
18.88