SIMILAR PATTERNS OF AMINO ACIDS FOR 4FJP_A_NPSA711_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1arl | APO-CARBOXYPEPTIDASEA=ALPHA= (COX) (Bos taurus) |
PF00246(Peptidase_M14) | 5 | THR A 129GLY A 115PRO A 113ASN A 112GLY A 44 | None | 0.96A | 4fjpA-1arlA:undetectable | 4fjpA-1arlA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aye | PROCARBOXYPEPTIDASEA2 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 129GLY A 115PRO A 113ASN A 112 | None | 0.86A | 4fjpA-1ayeA:undetectable | 4fjpA-1ayeA:23.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1biy | LACTOFERRIN (Bubalus bubalis) |
PF00405(Transferrin) | 6 | THR A 430GLY A 432PRO A 593ASN A 594TYR A 660GLY A 662 | None | 0.44A | 4fjpA-1biyA:55.3 | 4fjpA-1biyA:91.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cc1 | HYDROGENASE (LARGESUBUNIT) (Desulfomicrobiumbaculatum) |
PF00374(NiFeSe_Hases) | 4 | GLY L 462PRO L 454TYR L 317GLY L 44 | None | 0.73A | 4fjpA-1cc1L:undetectable | 4fjpA-1cc1L:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqj | SUCCINYL-COASYNTHETASE ALPHACHAIN (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 4 | GLY A 41PRO A 40ASN A 54GLY A 14 | NoneCOA A 901 (-4.4A)NoneCOA A 901 (-3.6A) | 0.86A | 4fjpA-1cqjA:undetectable | 4fjpA-1cqjA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dtd | CARBOXYPEPTIDASE A2 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 484GLY A 470PRO A 468ASN A 467 | None | 0.85A | 4fjpA-1dtdA:undetectable | 4fjpA-1dtdA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h74 | HOMOSERINE KINASE (Methanocaldococcusjannaschii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | THR A 14GLY A 96ASN A 141GLY A 104 | NoneADP A 400 ( 4.0A)ILE A 500 (-4.2A)None | 0.74A | 4fjpA-1h74A:undetectable | 4fjpA-1h74A:22.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1h76 | SEROTRANSFERRIN (Sus scrofa) |
PF00405(Transferrin) | 5 | GLY A 430PRO A 592ASN A 593TYR A 658GLY A 660 | None | 0.43A | 4fjpA-1h76A:50.6 | 4fjpA-1h76A:31.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1i6q | LACTOFERRIN (Camelusdromedarius) |
PF00405(Transferrin) | 5 | GLY A 432PRO A 593ASN A 594TYR A 660GLY A 662 | None | 0.65A | 4fjpA-1i6qA:27.4 | 4fjpA-1i6qA:55.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jnf | SEROTRANSFERRIN (Oryctolaguscuniculus) |
PF00405(Transferrin) | 5 | GLY A 424PRO A 580ASN A 581TYR A 647GLY A 649 | None | 0.46A | 4fjpA-1jnfA:50.2 | 4fjpA-1jnfA:30.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k4q | GLUTATHIONEREDUCTASE (Homo sapiens) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 156GLY A 158PRO A 293ASN A 294 | FAD A 499 (-3.9A)NoneNoneFAD A 499 ( 4.5A) | 0.91A | 4fjpA-1k4qA:undetectable | 4fjpA-1k4qA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kwm | PROCARBOXYPEPTIDASEB (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 129GLY A 115ASN A 112GLY A 44 | None | 0.78A | 4fjpA-1kwmA:undetectable | 4fjpA-1kwmA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ltd | FLAVOCYTOCHROME B2 (Saccharomycescerevisiae) |
PF00173(Cyt-b5)PF01070(FMN_dh) | 4 | THR A 153GLY A 374ASN A 372GLY A 287 | NoneFMN A 570 (-3.3A)NoneNone | 0.88A | 4fjpA-1ltdA:undetectable | 4fjpA-1ltdA:21.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1n76 | LACTOFERRIN (Homo sapiens) |
PF00405(Transferrin) | 5 | GLY A 434PRO A 595ASN A 596TYR A 662GLY A 664 | None | 0.40A | 4fjpA-1n76A:53.0 | 4fjpA-1n76A:68.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n94 | PROTEINFARNESYLTRANSFERASEBETA SUBUNIT (Rattusnorvegicus) |
PF00432(Prenyltrans) | 4 | THR B 153GLY B 141PRO B 148TYR B 180 | None | 0.90A | 4fjpA-1n94B:undetectable | 4fjpA-1n94B:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsa | PROCARBOXYPEPTIDASEB (Sus scrofa) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 129GLY A 115ASN A 112GLY A 44 | None | 0.84A | 4fjpA-1nsaA:undetectable | 4fjpA-1nsaA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pca | PROCARBOXYPEPTIDASEA PCPA (Sus scrofa) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 5 | THR A 129GLY A 115PRO A 113ASN A 112GLY A 44 | None | 0.97A | 4fjpA-1pcaA:undetectable | 4fjpA-1pcaA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1r | PUTIDAREDOXINREDUCTASE (Pseudomonasputida) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 4 | THR A 110GLY A 112PRO A 250ASN A 251 | FAD A 749 (-4.2A)FAD A 749 (-4.6A)NoneFAD A 749 ( 4.6A) | 0.68A | 4fjpA-1q1rA:undetectable | 4fjpA-1q1rA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | CYTOCHROME B6 (Chlamydomonasreinhardtii) |
PF00033(Cytochrome_B) | 4 | THR B 107GLY B 109TYR B 34GLY B 37 | NoneHEM B 901 (-3.9A)NoneHEM B 901 (-3.1A) | 0.88A | 4fjpA-1q90B:undetectable | 4fjpA-1q90B:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcw | FLAVOCYTOCHROME B2 (Saccharomycescerevisiae) |
PF01070(FMN_dh) | 4 | THR A 153GLY A 374ASN A 372GLY A 287 | NoneFNS A 570 (-3.2A)NoneNone | 0.86A | 4fjpA-1qcwA:undetectable | 4fjpA-1qcwA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qho | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | GLY A 91ASN A 77TYR A 46GLY A 49 | NoneNoneNone CA A 698 ( 4.9A) | 0.86A | 4fjpA-1qhoA:undetectable | 4fjpA-1qhoA:18.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qjm | LACTOFERRIN (Equus caballus) |
PF00405(Transferrin) | 5 | GLY A 432PRO A 593ASN A 594TYR A 660GLY A 662 | None | 0.49A | 4fjpA-1qjmA:53.4 | 4fjpA-1qjmA:45.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1suv | SEROTRANSFERRIN,C-LOBE (Homo sapiens) |
PF00405(Transferrin) | 5 | GLY E 424PRO E 580ASN E 581TYR E 647GLY E 649 | None | 0.46A | 4fjpA-1suvE:50.0 | 4fjpA-1suvE:58.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uh9 | HIZOPUSPEPSIN I (Rhizopusmicrosporus) |
PF00026(Asp) | 4 | THR A 36GLY A 220TYR A 169GLY A 19 | None | 0.89A | 4fjpA-1uh9A:undetectable | 4fjpA-1uh9A:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | GLY A 112PRO A 110ASN A 109GLY A 37 | None | 0.91A | 4fjpA-1uwyA:undetectable | 4fjpA-1uwyA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkh | FERRIPYOVERDINERECEPTOR (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | THR A 154GLY A 221ASN A 267GLY A 258 | None | 0.83A | 4fjpA-1xkhA:undetectable | 4fjpA-1xkhA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkq | SHORT-CHAINREDUCTASE FAMILYMEMBER (5D234) (Caenorhabditiselegans) |
PF13561(adh_short_C2) | 4 | THR A 200GLY A 198TYR A 214GLY A 230 | NoneNDP A1281 (-3.4A)NoneNone | 0.82A | 4fjpA-1xkqA:undetectable | 4fjpA-1xkqA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zli | CARBOXYPEPTIDASE B (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 129GLY A 115ASN A 112GLY A 44 | None | 0.81A | 4fjpA-1zliA:undetectable | 4fjpA-1zliA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2boa | CARBOXYPEPTIDASE A4 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A1129GLY A1115PRO A1113ASN A1112 | None | 0.86A | 4fjpA-2boaA:undetectable | 4fjpA-2boaA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1c | CARBOXYPEPTIDASE B (Helicoverpa zea) |
PF00246(Peptidase_M14) | 5 | THR A 129GLY A 115PRO A 113ASN A 112GLY A 44 | None | 0.89A | 4fjpA-2c1cA:undetectable | 4fjpA-2c1cA:21.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2hau | SEROTRANSFERRIN (Homo sapiens) |
PF00405(Transferrin) | 5 | GLY A 425PRO A 583ASN A 584TYR A 650GLY A 652 | None | 0.74A | 4fjpA-2hauA:26.9 | 4fjpA-2hauA:31.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv2 | FORMATEDEHYDROGENASE H (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | THR X 130GLY X 380ASN X 132GLY X 345 | None | 0.84A | 4fjpA-2iv2X:undetectable | 4fjpA-2iv2X:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l4d | SCO1/SENC FAMILYPROTEIN/CYTOCHROME C (Pseudomonasputida) |
PF00034(Cytochrom_C) | 4 | THR A 15GLY A 17ASN A 18GLY A 22 | None | 0.87A | 4fjpA-2l4dA:undetectable | 4fjpA-2l4dA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nsm | CARBOXYPEPTIDASE NCATALYTIC CHAIN (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | GLY A 113PRO A 111ASN A 110GLY A 37 | None | 0.86A | 4fjpA-2nsmA:undetectable | 4fjpA-2nsmA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5p | FERRIPYOVERDINERECEPTOR (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07660(STN)PF07715(Plug) | 4 | THR A 154GLY A 221ASN A 267GLY A 258 | None | 0.83A | 4fjpA-2o5pA:undetectable | 4fjpA-2o5pA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcu | CARBOXYPEPTIDASE A4 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 129GLY A 115PRO A 113ASN A 112 | None | 0.84A | 4fjpA-2pcuA:undetectable | 4fjpA-2pcuA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv3 | VACUOLATINGCYTOTOXIN (Helicobacterpylori) |
PF02691(VacA) | 4 | THR A 478GLY A 481ASN A 484GLY A 557 | None | 0.90A | 4fjpA-2qv3A:undetectable | 4fjpA-2qv3A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9z | GLUTATHIONE AMIDEREDUCTASE (Marichromatiumgracile) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | THR A 138GLY A 140PRO A 264ASN A 265GLY A 305 | FAD A 500 (-3.9A)NoneNoneFAD A 500 ( 4.7A)None | 1.11A | 4fjpA-2r9zA:undetectable | 4fjpA-2r9zA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT ALPHA (Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | GLY A 264PRO A 261TYR A 254GLY A 257 | None | 0.87A | 4fjpA-2v4jA:undetectable | 4fjpA-2v4jA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ya1 | PUTATIVE ALKALINEAMYLOPULLULANASE (Streptococcuspneumoniae) |
PF00128(Alpha-amylase)PF02922(CBM_48)PF03714(PUD) | 4 | THR A 751GLY A 749TYR A 812GLY A 781 | None | 0.81A | 4fjpA-2ya1A:undetectable | 4fjpA-2ya1A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ya2 | PUTATIVE ALKALINEAMYLOPULLULANASE (Streptococcuspneumoniae) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | THR A 296GLY A 294TYR A 357GLY A 326 | None | 0.82A | 4fjpA-2ya2A:undetectable | 4fjpA-2ya2A:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zoo | PROBABLE NITRITEREDUCTASE (Pseudoalteromonashaloplanktis) |
PF00034(Cytochrom_C)PF00394(Cu-oxidase)PF07732(Cu-oxidase_3) | 4 | GLY A 360PRO A 366TYR A 400GLY A 402 | NoneHEM A 600 (-3.9A)NoneHEM A 600 (-3.7A) | 0.89A | 4fjpA-2zooA:undetectable | 4fjpA-2zooA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases) | 4 | GLY A 560PRO A 552TYR A 395GLY A 50 | None | 0.88A | 4fjpA-3ayxA:undetectable | 4fjpA-3ayxA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cjx | PROTEIN OF UNKNOWNFUNCTION WITH ACUPIN-LIKE FOLD (Cupriaviduspinatubonensis) |
no annotation | 4 | THR A 58GLY A 56PRO A 106TYR A 78 | None | 0.80A | 4fjpA-3cjxA:undetectable | 4fjpA-3cjxA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fju | CARBOXYPEPTIDASE A1 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 129GLY A 115ASN A 112GLY A 44 | None | 0.86A | 4fjpA-3fjuA:undetectable | 4fjpA-3fjuA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fju | CARBOXYPEPTIDASE A1 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 129GLY A 115PRO A 113ASN A 112 | None | 0.86A | 4fjpA-3fjuA:undetectable | 4fjpA-3fjuA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flb | RIFR (Amycolatopsismediterranei) |
PF00975(Thioesterase) | 4 | GLY A 92PRO A 27TYR A 54GLY A 30 | None | 0.88A | 4fjpA-3flbA:undetectable | 4fjpA-3flbA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1l | MITOCHONDRIALUBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEXCORE PROTEIN 2 (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 4 | THR B 77GLY B 79ASN B 125GLY B 88 | None | 0.90A | 4fjpA-3h1lB:undetectable | 4fjpA-3h1lB:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | THR A 187GLY A 237PRO A 244ASN A 290 | None | 0.90A | 4fjpA-3ldrA:undetectable | 4fjpA-3ldrA:19.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mc2 | INHIBITOR OFCARBONIC ANHYDRASE (Mus musculus) |
PF00405(Transferrin) | 5 | GLY A 426PRO A 586ASN A 587TYR A 652GLY A 654 | None | 0.77A | 4fjpA-3mc2A:17.1 | 4fjpA-3mc2A:33.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mn8 | LP15968P (Drosophilamelanogaster) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | GLY A 147PRO A 145ASN A 144GLY A 72 | None | 0.85A | 4fjpA-3mn8A:undetectable | 4fjpA-3mn8A:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myr | NICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Allochromatiumvinosum) |
PF00374(NiFeSe_Hases) | 4 | GLY B1524PRO B1516TYR B1373GLY B1035 | None | 0.84A | 4fjpA-3myrB:undetectable | 4fjpA-3myrB:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oj0 | GLUTAMYL-TRNAREDUCTASE (Thermoplasmavolcanium) |
PF01488(Shikimate_DH) | 4 | THR A 83GLY A 107PRO A 110ASN A 111 | NoneGOL A 146 (-3.9A)NoneNone | 0.83A | 4fjpA-3oj0A:undetectable | 4fjpA-3oj0A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgw | MEMBRANE-BOUNDHYDROGENASE (NIFE)LARGE SUBUNIT HOXG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 4 | GLY L 567PRO L 559TYR L 396GLY L 49 | None | 0.84A | 4fjpA-3rgwL:undetectable | 4fjpA-3rgwL:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sgz | HYDROXYACID OXIDASE2 (Rattusnorvegicus) |
PF01070(FMN_dh) | 4 | THR A 33GLY A 248ASN A 246GLY A 162 | NoneFMN A 401 (-3.3A)NoneNone | 0.77A | 4fjpA-3sgzA:undetectable | 4fjpA-3sgzA:21.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3skp | SEROTRANSFERRIN (Homo sapiens) |
PF00405(Transferrin) | 5 | GLY A 425PRO A 583ASN A 584TYR A 650GLY A 652 | NoneNoneNoneNoneSO4 A 683 (-3.4A) | 0.80A | 4fjpA-3skpA:25.7 | 4fjpA-3skpA:59.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tql | ARGININE-BINDINGPROTEIN (Coxiellaburnetii) |
PF00497(SBP_bac_3) | 5 | THR A 126GLY A 229ASN A 127TYR A 54GLY A 106 | NoneNoneNoneNoneARG A 1 (-4.0A) | 1.46A | 4fjpA-3tqlA:8.3 | 4fjpA-3tqlA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 4 | GLY L 546PRO L 538TYR L 395GLY L 50 | None | 0.90A | 4fjpA-3uscL:undetectable | 4fjpA-3uscL:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ze7 | PERIPLASMIC [NIFESE]HYDROGENASE, LARGESUBUNIT,SELENOCYSTEINE-CONTAINING (Desulfovibriovulgaris) |
PF00374(NiFeSe_Hases) | 4 | GLY B 459PRO B 451TYR B 313GLY B 49 | None | 0.69A | 4fjpA-3ze7B:undetectable | 4fjpA-3ze7B:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv6 | APOPTOSIS-INDUCINGFACTOR 1,MITOCHONDRIAL (Homo sapiens) |
PF07992(Pyr_redox_2)PF14721(AIF_C) | 4 | THR A 260GLY A 262PRO A 402ASN A 403 | FAD A1449 (-4.1A)NoneNoneFAD A1449 ( 4.5A) | 0.83A | 4fjpA-4bv6A:undetectable | 4fjpA-4bv6A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3o | HYDROGENASE-1 LARGESUBUNIT (Salmonellaenterica) |
PF00374(NiFeSe_Hases) | 4 | GLY A 549PRO A 541TYR A 398GLY A 50 | None | 0.87A | 4fjpA-4c3oA:undetectable | 4fjpA-4c3oA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cw5 | DFNA (Bacillusvelezensis) |
PF03060(NMO) | 4 | THR A 329GLY A 559ASN A 562GLY A 335 | NoneFMN A1753 (-3.0A)NoneNone | 0.91A | 4fjpA-4cw5A:undetectable | 4fjpA-4cw5A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dji | PROBABLEGLUTAMATE/GAMMA-AMINOBUTYRATE ANTIPORTER (Escherichiacoli) |
PF13520(AA_permease_2) | 4 | GLY A 336PRO A 338TYR A 317GLY A 315 | None | 0.91A | 4fjpA-4djiA:undetectable | 4fjpA-4djiA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dup | QUINONEOXIDOREDUCTASE (Rhizobium etli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 176GLY A 153TYR A 225GLY A 222 | None | 0.90A | 4fjpA-4dupA:undetectable | 4fjpA-4dupA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2o | ALPHA-AMYLASE (Geobacillusthermoleovorans) |
PF00128(Alpha-amylase) | 4 | GLY A 103ASN A 96TYR A 65GLY A 68 | None | 0.91A | 4fjpA-4e2oA:undetectable | 4fjpA-4e2oA:21.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fim | LACTOTRANSFERRIN (Bos taurus) |
PF00405(Transferrin) | 6 | THR A 430GLY A 432PRO A 593ASN A 594TYR A 660GLY A 662 | NoneCEL A 711 (-3.7A)CEL A 711 (-4.3A)NoneCEL A 711 (-4.4A)CEL A 711 (-3.3A) | 0.19A | 4fjpA-4fimA:61.2 | 4fjpA-4fimA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g9i | HYDROGENASEMATURATION PROTEINHYPF (Thermococcuskodakarensis) |
PF00708(Acylphosphatase)PF00814(Peptidase_M22)PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 4 | THR A 466GLY A 404ASN A 409GLY A 512 | None | 0.88A | 4fjpA-4g9iA:undetectable | 4fjpA-4g9iA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le7 | PYOCIN L1 (Pseudomonasaeruginosa) |
PF01453(B_lectin) | 4 | GLY A 22PRO A 20ASN A 21GLY A 241 | NoneEDO A 305 ( 4.5A)NoneNone | 0.91A | 4fjpA-4le7A:undetectable | 4fjpA-4le7A:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lry | PTS-DEPENDENTDIHYDROXYACETONEKINASE,DIHYDROXYACETONE-BINDING SUBUNIT DHAK (Escherichiacoli) |
PF02733(Dak1) | 4 | THR A 288GLY A 286ASN A 284GLY A 188 | None | 0.82A | 4fjpA-4lryA:undetectable | 4fjpA-4lryA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASE (Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | THR B 669GLY B 673PRO B 472GLY B 474 | None | 0.89A | 4fjpA-4qiwB:undetectable | 4fjpA-4qiwB:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r72 | ABC-TYPE FE3+TRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Actinobacilluspleuropneumoniae) |
PF13343(SBP_bac_6) | 4 | THR A 260GLY A 265ASN A 17GLY A 58 | None | 0.88A | 4fjpA-4r72A:6.8 | 4fjpA-4r72A:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubq | BETA-LACTAMASE (Acinetobacterbaumannii) |
no annotation | 4 | THR A 141GLY A 139ASN A 144GLY A 167 | NoneNoneNoneACT A 303 ( 3.7A) | 0.88A | 4fjpA-4ubqA:undetectable | 4fjpA-4ubqA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uf4 | CARBOXYPEPTIDASE A1 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 239GLY A 225ASN A 222GLY A 154 | None | 0.88A | 4fjpA-4uf4A:undetectable | 4fjpA-4uf4A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uf4 | CARBOXYPEPTIDASE A1 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 239GLY A 225PRO A 223ASN A 222 | None | 0.87A | 4fjpA-4uf4A:undetectable | 4fjpA-4uf4A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7v | CELLULASE (Xanthomonascitri) |
PF00150(Cellulase) | 4 | THR A 232GLY A 230TYR A 265GLY A 224 | None | 0.76A | 4fjpA-4w7vA:undetectable | 4fjpA-4w7vA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 4 | THR A 333GLY A 284PRO A 282GLY A 256 | NoneNoneFAD A 503 (-4.5A)None | 0.79A | 4fjpA-4x4jA:undetectable | 4fjpA-4x4jA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yam | BETA-ETHERASE (Sphingobium sp.SYK-6) |
PF13417(GST_N_3) | 5 | GLY A 180PRO A 184ASN A 185TYR A 189GLY A 220 | None | 0.95A | 4fjpA-4yamA:undetectable | 4fjpA-4yamA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ysw | XANTHINEDEHYDROGENASE/OXIDASE (Rattusnorvegicus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | THR A 870GLY A 868PRO A 906GLY A 664 | GOL A3008 (-4.8A)NoneGOL A3008 ( 4.7A)None | 0.90A | 4fjpA-4yswA:undetectable | 4fjpA-4yswA:13.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9r | OMEGA-3POLYUNSATURATEDFATTY ACID SYNTHASESUBUNIT PFAD (Shewanellaoneidensis) |
PF03060(NMO) | 4 | THR A 357GLY A 488PRO A 485GLY A 275 | NoneNoneNoneFMN A 602 ( 4.3A) | 0.82A | 4fjpA-4z9rA:undetectable | 4fjpA-4z9rA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zej | METALLO-BETA-LACTAMASE (Pseudomonasstutzeri) |
no annotation | 4 | THR A 140GLY A 138ASN A 143GLY A 169 | NoneNoneNone CL A 305 ( 4.5A) | 0.89A | 4fjpA-4zejA:undetectable | 4fjpA-4zejA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a2a | APO FORM OFANOXYBACILLUSALPHA-AMYLASES (Anoxybacillusayderensis) |
PF00128(Alpha-amylase) | 4 | GLY A 99ASN A 92TYR A 61GLY A 64 | NoneNoneNone CA A1481 ( 4.9A) | 0.85A | 4fjpA-5a2aA:undetectable | 4fjpA-5a2aA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa5 | NIFE-HYDROGENASELARGE SUBUNIT, HOFG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 4 | THR C 524GLY C 577PRO C 575GLY C 82 | NFU C 701 (-3.8A)NoneNoneNone | 0.84A | 4fjpA-5aa5C:undetectable | 4fjpA-5aa5C:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3r | IMP-18 (Pseudomonasaeruginosa) |
no annotation | 4 | THR A 158GLY A 156ASN A 161GLY A 184 | NoneNoneNoneCIT A2003 (-3.6A) | 0.90A | 4fjpA-5b3rA:undetectable | 4fjpA-5b3rA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ca5 | NONO-1 (Caenorhabditiselegans) |
PF00076(RRM_1)PF08075(NOPS) | 4 | GLY A 151PRO A 124ASN A 125GLY A 177 | None | 0.83A | 4fjpA-5ca5A:undetectable | 4fjpA-5ca5A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fkc | BETA-FRUCTOFURANOSIDASE (Xanthophyllomycesdendrorhous) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | THR A 217GLY A 253ASN A 301GLY A 286 | None | 0.85A | 4fjpA-5fkcA:undetectable | 4fjpA-5fkcA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hgq | LYSINE--TRNA LIGASE (Loa loa) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | GLY A 309PRO A 307ASN A 495TYR A 305 | None | 0.89A | 4fjpA-5hgqA:undetectable | 4fjpA-5hgqA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxd | PROTEIN MPAA (Escherichiacoli) |
PF00246(Peptidase_M14) | 4 | GLY A 83PRO A 81ASN A 80GLY A 26 | None | 0.91A | 4fjpA-5hxdA:undetectable | 4fjpA-5hxdA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i1t | STAGE II SPORULATIONPROTEIN D (Clostridioidesdifficile) |
PF08486(SpoIID) | 4 | THR A 202GLY A 200PRO A 222GLY A 329 | NoneNoneGOL A 406 ( 4.9A)None | 0.90A | 4fjpA-5i1tA:undetectable | 4fjpA-5i1tA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1q | CARBOXYPEPTIDASE B (Sus scrofa) |
PF00246(Peptidase_M14) | 4 | THR A 129GLY A 115ASN A 112GLY A 44 | None | 0.78A | 4fjpA-5j1qA:undetectable | 4fjpA-5j1qA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwz | CELLULOSE-BINDINGFAMILY II (Streptomycessp. SirexAA-E) |
PF02012(BNR) | 4 | GLY A 193PRO A 150ASN A 191GLY A 123 | None | 0.82A | 4fjpA-5jwzA:undetectable | 4fjpA-5jwzA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mmd | METALLO-BETA-LACTAMASE 1 (Acinetobacterbaumannii) |
PF00753(Lactamase_B) | 4 | THR E 197GLY E 195ASN E 200GLY E 232 | ZN E 403 ( 4.9A)NoneNone CL E 404 ( 4.8A) | 0.90A | 4fjpA-5mmdE:undetectable | 4fjpA-5mmdE:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbs | BETA-GLUCOSIDASE (Neurosporacrassa) |
no annotation | 4 | THR A 159GLY A 145PRO A 148GLY A 604 | None | 0.90A | 4fjpA-5nbsA:undetectable | 4fjpA-5nbsA:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ng6 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Francisellatularensis) |
no annotation | 4 | GLY A1090PRO A1087TYR A1260GLY A1258 | None | 0.89A | 4fjpA-5ng6A:undetectable | 4fjpA-5ng6A:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vhj | 26S PROTEASOMEREGULATORY SUBUNIT 4 (Homo sapiens) |
PF00004(AAA) | 4 | THR B 331GLY B 229PRO B 227ASN B 332 | None | 0.89A | 4fjpA-5vhjB:undetectable | 4fjpA-5vhjB:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1y | MERCURIC REDUCTASE (Lysinibacillussphaericus) |
no annotation | 4 | THR B 117GLY B 119ASN B 124GLY B 220 | NoneNoneNoneFAD B 601 (-3.1A) | 0.90A | 4fjpA-5x1yB:undetectable | 4fjpA-5x1yB:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z06 | BDI_3064 PROTEIN (Parabacteroidesdistasonis) |
no annotation | 4 | GLY A 333ASN A 330TYR A 315GLY A 319 | None | 0.90A | 4fjpA-5z06A:undetectable | 4fjpA-5z06A:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b4o | GLUTATHIONEREDUCTASE (Enterococcusfaecalis) |
no annotation | 4 | THR A 138GLY A 140PRO A 264ASN A 265 | FAD A 501 (-3.9A)NoneNoneFAD A 501 ( 4.8A) | 0.74A | 4fjpA-6b4oA:undetectable | 4fjpA-6b4oA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f45 | - (-) |
no annotation | 5 | THR D 118GLY D 126PRO D 128ASN D 127GLY D 228 | None | 1.23A | 4fjpA-6f45D:undetectable | 4fjpA-6f45D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f79 | - (-) |
no annotation | 4 | GLY A 115PRO A 113ASN A 112GLY A 41 | None | 0.82A | 4fjpA-6f79A:undetectable | 4fjpA-6f79A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fht | BACTERIOPHYTOCHROME,ADENYLATE CYCLASE (Deinococcusradiodurans;Synechocystissp. PCC 6803) |
no annotation | 4 | GLY A 600PRO A 602TYR A 662GLY A 516 | None | 0.82A | 4fjpA-6fhtA:undetectable | 4fjpA-6fhtA:13.04 |