SIMILAR PATTERNS OF AMINO ACIDS FOR 4FJP_A_NPSA711

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1arl APO-CARBOXYPEPTIDASE
A=ALPHA= (COX)


(Bos taurus)
PF00246
(Peptidase_M14)
5 THR A 129
GLY A 115
PRO A 113
ASN A 112
GLY A  44
None
0.96A 4fjpA-1arlA:
undetectable
4fjpA-1arlA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2


(Homo sapiens)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A 129
GLY A 115
PRO A 113
ASN A 112
None
0.86A 4fjpA-1ayeA:
undetectable
4fjpA-1ayeA:
23.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1biy LACTOFERRIN

(Bubalus bubalis)
PF00405
(Transferrin)
6 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
None
0.44A 4fjpA-1biyA:
55.3
4fjpA-1biyA:
91.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cc1 HYDROGENASE (LARGE
SUBUNIT)


(Desulfomicrobium
baculatum)
PF00374
(NiFeSe_Hases)
4 GLY L 462
PRO L 454
TYR L 317
GLY L  44
None
0.73A 4fjpA-1cc1L:
undetectable
4fjpA-1cc1L:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqj SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN


(Escherichia
coli)
PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
4 GLY A  41
PRO A  40
ASN A  54
GLY A  14
None
COA  A 901 (-4.4A)
None
COA  A 901 (-3.6A)
0.86A 4fjpA-1cqjA:
undetectable
4fjpA-1cqjA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens)
PF00246
(Peptidase_M14)
4 THR A 484
GLY A 470
PRO A 468
ASN A 467
None
0.85A 4fjpA-1dtdA:
undetectable
4fjpA-1dtdA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h74 HOMOSERINE KINASE

(Methanocaldococcus
jannaschii)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
4 THR A  14
GLY A  96
ASN A 141
GLY A 104
None
ADP  A 400 ( 4.0A)
ILE  A 500 (-4.2A)
None
0.74A 4fjpA-1h74A:
undetectable
4fjpA-1h74A:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h76 SEROTRANSFERRIN

(Sus scrofa)
PF00405
(Transferrin)
5 GLY A 430
PRO A 592
ASN A 593
TYR A 658
GLY A 660
None
0.43A 4fjpA-1h76A:
50.6
4fjpA-1h76A:
31.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i6q LACTOFERRIN

(Camelus
dromedarius)
PF00405
(Transferrin)
5 GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
None
0.65A 4fjpA-1i6qA:
27.4
4fjpA-1i6qA:
55.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jnf SEROTRANSFERRIN

(Oryctolagus
cuniculus)
PF00405
(Transferrin)
5 GLY A 424
PRO A 580
ASN A 581
TYR A 647
GLY A 649
None
0.46A 4fjpA-1jnfA:
50.2
4fjpA-1jnfA:
30.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k4q GLUTATHIONE
REDUCTASE


(Homo sapiens)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 THR A 156
GLY A 158
PRO A 293
ASN A 294
FAD  A 499 (-3.9A)
None
None
FAD  A 499 ( 4.5A)
0.91A 4fjpA-1k4qA:
undetectable
4fjpA-1k4qA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwm PROCARBOXYPEPTIDASE
B


(Homo sapiens)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A 129
GLY A 115
ASN A 112
GLY A  44
None
0.78A 4fjpA-1kwmA:
undetectable
4fjpA-1kwmA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltd FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae)
PF00173
(Cyt-b5)
PF01070
(FMN_dh)
4 THR A 153
GLY A 374
ASN A 372
GLY A 287
None
FMN  A 570 (-3.3A)
None
None
0.88A 4fjpA-1ltdA:
undetectable
4fjpA-1ltdA:
21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1n76 LACTOFERRIN

(Homo sapiens)
PF00405
(Transferrin)
5 GLY A 434
PRO A 595
ASN A 596
TYR A 662
GLY A 664
None
0.40A 4fjpA-1n76A:
53.0
4fjpA-1n76A:
68.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n94 PROTEIN
FARNESYLTRANSFERASE
BETA SUBUNIT


(Rattus
norvegicus)
PF00432
(Prenyltrans)
4 THR B 153
GLY B 141
PRO B 148
TYR B 180
None
0.90A 4fjpA-1n94B:
undetectable
4fjpA-1n94B:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nsa PROCARBOXYPEPTIDASE
B


(Sus scrofa)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A 129
GLY A 115
ASN A 112
GLY A  44
None
0.84A 4fjpA-1nsaA:
undetectable
4fjpA-1nsaA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pca PROCARBOXYPEPTIDASE
A PCPA


(Sus scrofa)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
5 THR A 129
GLY A 115
PRO A 113
ASN A 112
GLY A  44
None
0.97A 4fjpA-1pcaA:
undetectable
4fjpA-1pcaA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1r PUTIDAREDOXIN
REDUCTASE


(Pseudomonas
putida)
PF07992
(Pyr_redox_2)
PF14759
(Reductase_C)
4 THR A 110
GLY A 112
PRO A 250
ASN A 251
FAD  A 749 (-4.2A)
FAD  A 749 (-4.6A)
None
FAD  A 749 ( 4.6A)
0.68A 4fjpA-1q1rA:
undetectable
4fjpA-1q1rA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q90 CYTOCHROME B6

(Chlamydomonas
reinhardtii)
PF00033
(Cytochrome_B)
4 THR B 107
GLY B 109
TYR B  34
GLY B  37
None
HEM  B 901 (-3.9A)
None
HEM  B 901 (-3.1A)
0.88A 4fjpA-1q90B:
undetectable
4fjpA-1q90B:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcw FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae)
PF01070
(FMN_dh)
4 THR A 153
GLY A 374
ASN A 372
GLY A 287
None
FNS  A 570 (-3.2A)
None
None
0.86A 4fjpA-1qcwA:
undetectable
4fjpA-1qcwA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C)
4 GLY A  91
ASN A  77
TYR A  46
GLY A  49
None
None
None
CA  A 698 ( 4.9A)
0.86A 4fjpA-1qhoA:
undetectable
4fjpA-1qhoA:
18.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qjm LACTOFERRIN

(Equus caballus)
PF00405
(Transferrin)
5 GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
None
0.49A 4fjpA-1qjmA:
53.4
4fjpA-1qjmA:
45.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1suv SEROTRANSFERRIN,
C-LOBE


(Homo sapiens)
PF00405
(Transferrin)
5 GLY E 424
PRO E 580
ASN E 581
TYR E 647
GLY E 649
None
0.46A 4fjpA-1suvE:
50.0
4fjpA-1suvE:
58.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uh9 HIZOPUSPEPSIN I

(Rhizopus
microsporus)
PF00026
(Asp)
4 THR A  36
GLY A 220
TYR A 169
GLY A  19
None
0.89A 4fjpA-1uh9A:
undetectable
4fjpA-1uh9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwy CARBOXYPEPTIDASE M

(Homo sapiens)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 GLY A 112
PRO A 110
ASN A 109
GLY A  37
None
0.91A 4fjpA-1uwyA:
undetectable
4fjpA-1uwyA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR


(Pseudomonas
aeruginosa)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 THR A 154
GLY A 221
ASN A 267
GLY A 258
None
0.83A 4fjpA-1xkhA:
undetectable
4fjpA-1xkhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkq SHORT-CHAIN
REDUCTASE FAMILY
MEMBER (5D234)


(Caenorhabditis
elegans)
PF13561
(adh_short_C2)
4 THR A 200
GLY A 198
TYR A 214
GLY A 230
None
NDP  A1281 (-3.4A)
None
None
0.82A 4fjpA-1xkqA:
undetectable
4fjpA-1xkqA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zli CARBOXYPEPTIDASE B

(Homo sapiens)
PF00246
(Peptidase_M14)
4 THR A 129
GLY A 115
ASN A 112
GLY A  44
None
0.81A 4fjpA-1zliA:
undetectable
4fjpA-1zliA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2boa CARBOXYPEPTIDASE A4

(Homo sapiens)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A1129
GLY A1115
PRO A1113
ASN A1112
None
0.86A 4fjpA-2boaA:
undetectable
4fjpA-2boaA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1c CARBOXYPEPTIDASE B

(Helicoverpa zea)
PF00246
(Peptidase_M14)
5 THR A 129
GLY A 115
PRO A 113
ASN A 112
GLY A  44
None
0.89A 4fjpA-2c1cA:
undetectable
4fjpA-2c1cA:
21.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hau SEROTRANSFERRIN

(Homo sapiens)
PF00405
(Transferrin)
5 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
None
0.74A 4fjpA-2hauA:
26.9
4fjpA-2hauA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv2 FORMATE
DEHYDROGENASE H


(Escherichia
coli)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
4 THR X 130
GLY X 380
ASN X 132
GLY X 345
None
0.84A 4fjpA-2iv2X:
undetectable
4fjpA-2iv2X:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4d SCO1/SENC FAMILY
PROTEIN/CYTOCHROME C


(Pseudomonas
putida)
PF00034
(Cytochrom_C)
4 THR A  15
GLY A  17
ASN A  18
GLY A  22
None
0.87A 4fjpA-2l4dA:
undetectable
4fjpA-2l4dA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nsm CARBOXYPEPTIDASE N
CATALYTIC CHAIN


(Homo sapiens)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 GLY A 113
PRO A 111
ASN A 110
GLY A  37
None
0.86A 4fjpA-2nsmA:
undetectable
4fjpA-2nsmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5p FERRIPYOVERDINE
RECEPTOR


(Pseudomonas
aeruginosa)
PF00593
(TonB_dep_Rec)
PF07660
(STN)
PF07715
(Plug)
4 THR A 154
GLY A 221
ASN A 267
GLY A 258
None
0.83A 4fjpA-2o5pA:
undetectable
4fjpA-2o5pA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcu CARBOXYPEPTIDASE A4

(Homo sapiens)
PF00246
(Peptidase_M14)
4 THR A 129
GLY A 115
PRO A 113
ASN A 112
None
0.84A 4fjpA-2pcuA:
undetectable
4fjpA-2pcuA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qv3 VACUOLATING
CYTOTOXIN


(Helicobacter
pylori)
PF02691
(VacA)
4 THR A 478
GLY A 481
ASN A 484
GLY A 557
None
0.90A 4fjpA-2qv3A:
undetectable
4fjpA-2qv3A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9z GLUTATHIONE AMIDE
REDUCTASE


(Marichromatium
gracile)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 THR A 138
GLY A 140
PRO A 264
ASN A 265
GLY A 305
FAD  A 500 (-3.9A)
None
None
FAD  A 500 ( 4.7A)
None
1.11A 4fjpA-2r9zA:
undetectable
4fjpA-2r9zA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA


(Desulfovibrio
vulgaris)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
4 GLY A 264
PRO A 261
TYR A 254
GLY A 257
None
0.87A 4fjpA-2v4jA:
undetectable
4fjpA-2v4jA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya1 PUTATIVE ALKALINE
AMYLOPULLULANASE


(Streptococcus
pneumoniae)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF03714
(PUD)
4 THR A 751
GLY A 749
TYR A 812
GLY A 781
None
0.81A 4fjpA-2ya1A:
undetectable
4fjpA-2ya1A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya2 PUTATIVE ALKALINE
AMYLOPULLULANASE


(Streptococcus
pneumoniae)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 THR A 296
GLY A 294
TYR A 357
GLY A 326
None
0.82A 4fjpA-2ya2A:
undetectable
4fjpA-2ya2A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoo PROBABLE NITRITE
REDUCTASE


(Pseudoalteromonas
haloplanktis)
PF00034
(Cytochrom_C)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3)
4 GLY A 360
PRO A 366
TYR A 400
GLY A 402
None
HEM  A 600 (-3.9A)
None
HEM  A 600 (-3.7A)
0.89A 4fjpA-2zooA:
undetectable
4fjpA-2zooA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT


(Hydrogenovibrio
marinus)
PF00374
(NiFeSe_Hases)
4 GLY A 560
PRO A 552
TYR A 395
GLY A  50
None
0.88A 4fjpA-3ayxA:
undetectable
4fjpA-3ayxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD


(Cupriavidus
pinatubonensis)
no annotation 4 THR A  58
GLY A  56
PRO A 106
TYR A  78
None
0.80A 4fjpA-3cjxA:
undetectable
4fjpA-3cjxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fju CARBOXYPEPTIDASE A1

(Homo sapiens)
PF00246
(Peptidase_M14)
4 THR A 129
GLY A 115
ASN A 112
GLY A  44
None
0.86A 4fjpA-3fjuA:
undetectable
4fjpA-3fjuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fju CARBOXYPEPTIDASE A1

(Homo sapiens)
PF00246
(Peptidase_M14)
4 THR A 129
GLY A 115
PRO A 113
ASN A 112
None
0.86A 4fjpA-3fjuA:
undetectable
4fjpA-3fjuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flb RIFR

(Amycolatopsis
mediterranei)
PF00975
(Thioesterase)
4 GLY A  92
PRO A  27
TYR A  54
GLY A  30
None
0.88A 4fjpA-3flbA:
undetectable
4fjpA-3flbA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
-C REDUCTASE COMPLEX
CORE PROTEIN 2


(Gallus gallus)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
4 THR B  77
GLY B  79
ASN B 125
GLY B  88
None
0.90A 4fjpA-3h1lB:
undetectable
4fjpA-3h1lB:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
4 THR A 187
GLY A 237
PRO A 244
ASN A 290
None
0.90A 4fjpA-3ldrA:
undetectable
4fjpA-3ldrA:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mc2 INHIBITOR OF
CARBONIC ANHYDRASE


(Mus musculus)
PF00405
(Transferrin)
5 GLY A 426
PRO A 586
ASN A 587
TYR A 652
GLY A 654
None
0.77A 4fjpA-3mc2A:
17.1
4fjpA-3mc2A:
33.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mn8 LP15968P

(Drosophila
melanogaster)
PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg)
4 GLY A 147
PRO A 145
ASN A 144
GLY A  72
None
0.85A 4fjpA-3mn8A:
undetectable
4fjpA-3mn8A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myr NICKEL-DEPENDENT
HYDROGENASE LARGE
SUBUNIT


(Allochromatium
vinosum)
PF00374
(NiFeSe_Hases)
4 GLY B1524
PRO B1516
TYR B1373
GLY B1035
None
0.84A 4fjpA-3myrB:
undetectable
4fjpA-3myrB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oj0 GLUTAMYL-TRNA
REDUCTASE


(Thermoplasma
volcanium)
PF01488
(Shikimate_DH)
4 THR A  83
GLY A 107
PRO A 110
ASN A 111
None
GOL  A 146 (-3.9A)
None
None
0.83A 4fjpA-3oj0A:
undetectable
4fjpA-3oj0A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rgw MEMBRANE-BOUND
HYDROGENASE (NIFE)
LARGE SUBUNIT HOXG


(Cupriavidus
necator)
PF00374
(NiFeSe_Hases)
4 GLY L 567
PRO L 559
TYR L 396
GLY L  49
None
0.84A 4fjpA-3rgwL:
undetectable
4fjpA-3rgwL:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgz HYDROXYACID OXIDASE
2


(Rattus
norvegicus)
PF01070
(FMN_dh)
4 THR A  33
GLY A 248
ASN A 246
GLY A 162
None
FMN  A 401 (-3.3A)
None
None
0.77A 4fjpA-3sgzA:
undetectable
4fjpA-3sgzA:
21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3skp SEROTRANSFERRIN

(Homo sapiens)
PF00405
(Transferrin)
5 GLY A 425
PRO A 583
ASN A 584
TYR A 650
GLY A 652
None
None
None
None
SO4  A 683 (-3.4A)
0.80A 4fjpA-3skpA:
25.7
4fjpA-3skpA:
59.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tql ARGININE-BINDING
PROTEIN


(Coxiella
burnetii)
PF00497
(SBP_bac_3)
5 THR A 126
GLY A 229
ASN A 127
TYR A  54
GLY A 106
None
None
None
None
ARG  A   1 (-4.0A)
1.46A 4fjpA-3tqlA:
8.3
4fjpA-3tqlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usc HYDROGENASE-1 LARGE
CHAIN


(Escherichia
coli)
PF00374
(NiFeSe_Hases)
4 GLY L 546
PRO L 538
TYR L 395
GLY L  50
None
0.90A 4fjpA-3uscL:
undetectable
4fjpA-3uscL:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ze7 PERIPLASMIC [NIFESE]
HYDROGENASE, LARGE
SUBUNIT,
SELENOCYSTEINE-CONTA
INING


(Desulfovibrio
vulgaris)
PF00374
(NiFeSe_Hases)
4 GLY B 459
PRO B 451
TYR B 313
GLY B  49
None
0.69A 4fjpA-3ze7B:
undetectable
4fjpA-3ze7B:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv6 APOPTOSIS-INDUCING
FACTOR 1,
MITOCHONDRIAL


(Homo sapiens)
PF07992
(Pyr_redox_2)
PF14721
(AIF_C)
4 THR A 260
GLY A 262
PRO A 402
ASN A 403
FAD  A1449 (-4.1A)
None
None
FAD  A1449 ( 4.5A)
0.83A 4fjpA-4bv6A:
undetectable
4fjpA-4bv6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3o HYDROGENASE-1 LARGE
SUBUNIT


(Salmonella
enterica)
PF00374
(NiFeSe_Hases)
4 GLY A 549
PRO A 541
TYR A 398
GLY A  50
None
0.87A 4fjpA-4c3oA:
undetectable
4fjpA-4c3oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cw5 DFNA

(Bacillus
velezensis)
PF03060
(NMO)
4 THR A 329
GLY A 559
ASN A 562
GLY A 335
None
FMN  A1753 (-3.0A)
None
None
0.91A 4fjpA-4cw5A:
undetectable
4fjpA-4cw5A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER


(Escherichia
coli)
PF13520
(AA_permease_2)
4 GLY A 336
PRO A 338
TYR A 317
GLY A 315
None
0.91A 4fjpA-4djiA:
undetectable
4fjpA-4djiA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dup QUINONE
OXIDOREDUCTASE


(Rhizobium etli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 THR A 176
GLY A 153
TYR A 225
GLY A 222
None
0.90A 4fjpA-4dupA:
undetectable
4fjpA-4dupA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2o ALPHA-AMYLASE

(Geobacillus
thermoleovorans)
PF00128
(Alpha-amylase)
4 GLY A 103
ASN A  96
TYR A  65
GLY A  68
None
0.91A 4fjpA-4e2oA:
undetectable
4fjpA-4e2oA:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fim LACTOTRANSFERRIN

(Bos taurus)
PF00405
(Transferrin)
6 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
None
CEL  A 711 (-3.7A)
CEL  A 711 (-4.3A)
None
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
0.19A 4fjpA-4fimA:
61.2
4fjpA-4fimA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9i HYDROGENASE
MATURATION PROTEIN
HYPF


(Thermococcus
kodakarensis)
PF00708
(Acylphosphatase)
PF00814
(Peptidase_M22)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF)
4 THR A 466
GLY A 404
ASN A 409
GLY A 512
None
0.88A 4fjpA-4g9iA:
undetectable
4fjpA-4g9iA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4le7 PYOCIN L1

(Pseudomonas
aeruginosa)
PF01453
(B_lectin)
4 GLY A  22
PRO A  20
ASN A  21
GLY A 241
None
EDO  A 305 ( 4.5A)
None
None
0.91A 4fjpA-4le7A:
undetectable
4fjpA-4le7A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lry PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
DIHYDROXYACETONE-BIN
DING SUBUNIT DHAK


(Escherichia
coli)
PF02733
(Dak1)
4 THR A 288
GLY A 286
ASN A 284
GLY A 188
None
0.82A 4fjpA-4lryA:
undetectable
4fjpA-4lryA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE


(Thermococcus
kodakarensis)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
4 THR B 669
GLY B 673
PRO B 472
GLY B 474
None
0.89A 4fjpA-4qiwB:
undetectable
4fjpA-4qiwB:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT


(Actinobacillus
pleuropneumoniae)
PF13343
(SBP_bac_6)
4 THR A 260
GLY A 265
ASN A  17
GLY A  58
None
0.88A 4fjpA-4r72A:
6.8
4fjpA-4r72A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ubq BETA-LACTAMASE

(Acinetobacter
baumannii)
no annotation 4 THR A 141
GLY A 139
ASN A 144
GLY A 167
None
None
None
ACT  A 303 ( 3.7A)
0.88A 4fjpA-4ubqA:
undetectable
4fjpA-4ubqA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uf4 CARBOXYPEPTIDASE A1

(Homo sapiens)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A 239
GLY A 225
ASN A 222
GLY A 154
None
0.88A 4fjpA-4uf4A:
undetectable
4fjpA-4uf4A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uf4 CARBOXYPEPTIDASE A1

(Homo sapiens)
PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
4 THR A 239
GLY A 225
PRO A 223
ASN A 222
None
0.87A 4fjpA-4uf4A:
undetectable
4fjpA-4uf4A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w7v CELLULASE

(Xanthomonas
citri)
PF00150
(Cellulase)
4 THR A 232
GLY A 230
TYR A 265
GLY A 224
None
0.76A 4fjpA-4w7vA:
undetectable
4fjpA-4w7vA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x4j PUTATIVE OXYGENASE

(Amycolatopsis
orientalis)
PF01494
(FAD_binding_3)
4 THR A 333
GLY A 284
PRO A 282
GLY A 256
None
None
FAD  A 503 (-4.5A)
None
0.79A 4fjpA-4x4jA:
undetectable
4fjpA-4x4jA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yam BETA-ETHERASE

(Sphingobium sp.
SYK-6)
PF13417
(GST_N_3)
5 GLY A 180
PRO A 184
ASN A 185
TYR A 189
GLY A 220
None
0.95A 4fjpA-4yamA:
undetectable
4fjpA-4yamA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E


(Rattus
norvegicus)
PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C)
4 THR A 870
GLY A 868
PRO A 906
GLY A 664
GOL  A3008 (-4.8A)
None
GOL  A3008 ( 4.7A)
None
0.90A 4fjpA-4yswA:
undetectable
4fjpA-4yswA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD


(Shewanella
oneidensis)
PF03060
(NMO)
4 THR A 357
GLY A 488
PRO A 485
GLY A 275
None
None
None
FMN  A 602 ( 4.3A)
0.82A 4fjpA-4z9rA:
undetectable
4fjpA-4z9rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zej METALLO-BETA-LACTAMA
SE


(Pseudomonas
stutzeri)
no annotation 4 THR A 140
GLY A 138
ASN A 143
GLY A 169
None
None
None
CL  A 305 ( 4.5A)
0.89A 4fjpA-4zejA:
undetectable
4fjpA-4zejA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a2a APO FORM OF
ANOXYBACILLUS
ALPHA-AMYLASES


(Anoxybacillus
ayderensis)
PF00128
(Alpha-amylase)
4 GLY A  99
ASN A  92
TYR A  61
GLY A  64
None
None
None
CA  A1481 ( 4.9A)
0.85A 4fjpA-5a2aA:
undetectable
4fjpA-5a2aA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG


(Cupriavidus
necator)
PF00374
(NiFeSe_Hases)
4 THR C 524
GLY C 577
PRO C 575
GLY C  82
NFU  C 701 (-3.8A)
None
None
None
0.84A 4fjpA-5aa5C:
undetectable
4fjpA-5aa5C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3r IMP-18

(Pseudomonas
aeruginosa)
no annotation 4 THR A 158
GLY A 156
ASN A 161
GLY A 184
None
None
None
CIT  A2003 (-3.6A)
0.90A 4fjpA-5b3rA:
undetectable
4fjpA-5b3rA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ca5 NONO-1

(Caenorhabditis
elegans)
PF00076
(RRM_1)
PF08075
(NOPS)
4 GLY A 151
PRO A 124
ASN A 125
GLY A 177
None
0.83A 4fjpA-5ca5A:
undetectable
4fjpA-5ca5A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkc BETA-FRUCTOFURANOSID
ASE


(Xanthophyllomyces
dendrorhous)
PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C)
4 THR A 217
GLY A 253
ASN A 301
GLY A 286
None
0.85A 4fjpA-5fkcA:
undetectable
4fjpA-5fkcA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hgq LYSINE--TRNA LIGASE

(Loa loa)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
4 GLY A 309
PRO A 307
ASN A 495
TYR A 305
None
0.89A 4fjpA-5hgqA:
undetectable
4fjpA-5hgqA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxd PROTEIN MPAA

(Escherichia
coli)
PF00246
(Peptidase_M14)
4 GLY A  83
PRO A  81
ASN A  80
GLY A  26
None
0.91A 4fjpA-5hxdA:
undetectable
4fjpA-5hxdA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1t STAGE II SPORULATION
PROTEIN D


(Clostridioides
difficile)
PF08486
(SpoIID)
4 THR A 202
GLY A 200
PRO A 222
GLY A 329
None
None
GOL  A 406 ( 4.9A)
None
0.90A 4fjpA-5i1tA:
undetectable
4fjpA-5i1tA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j1q CARBOXYPEPTIDASE B

(Sus scrofa)
PF00246
(Peptidase_M14)
4 THR A 129
GLY A 115
ASN A 112
GLY A  44
None
0.78A 4fjpA-5j1qA:
undetectable
4fjpA-5j1qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwz CELLULOSE-BINDING
FAMILY II


(Streptomyces
sp. SirexAA-E)
PF02012
(BNR)
4 GLY A 193
PRO A 150
ASN A 191
GLY A 123
None
0.82A 4fjpA-5jwzA:
undetectable
4fjpA-5jwzA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmd METALLO-BETA-LACTAMA
SE 1


(Acinetobacter
baumannii)
PF00753
(Lactamase_B)
4 THR E 197
GLY E 195
ASN E 200
GLY E 232
ZN  E 403 ( 4.9A)
None
None
CL  E 404 ( 4.8A)
0.90A 4fjpA-5mmdE:
undetectable
4fjpA-5mmdE:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbs BETA-GLUCOSIDASE

(Neurospora
crassa)
no annotation 4 THR A 159
GLY A 145
PRO A 148
GLY A 604
None
0.90A 4fjpA-5nbsA:
undetectable
4fjpA-5nbsA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ng6 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1


(Francisella
tularensis)
no annotation 4 GLY A1090
PRO A1087
TYR A1260
GLY A1258
None
0.89A 4fjpA-5ng6A:
undetectable
4fjpA-5ng6A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhj 26S PROTEASOME
REGULATORY SUBUNIT 4


(Homo sapiens)
PF00004
(AAA)
4 THR B 331
GLY B 229
PRO B 227
ASN B 332
None
0.89A 4fjpA-5vhjB:
undetectable
4fjpA-5vhjB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1y MERCURIC REDUCTASE

(Lysinibacillus
sphaericus)
no annotation 4 THR B 117
GLY B 119
ASN B 124
GLY B 220
None
None
None
FAD  B 601 (-3.1A)
0.90A 4fjpA-5x1yB:
undetectable
4fjpA-5x1yB:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z06 BDI_3064 PROTEIN

(Parabacteroides
distasonis)
no annotation 4 GLY A 333
ASN A 330
TYR A 315
GLY A 319
None
0.90A 4fjpA-5z06A:
undetectable
4fjpA-5z06A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b4o GLUTATHIONE
REDUCTASE


(Enterococcus
faecalis)
no annotation 4 THR A 138
GLY A 140
PRO A 264
ASN A 265
FAD  A 501 (-3.9A)
None
None
FAD  A 501 ( 4.8A)
0.74A 4fjpA-6b4oA:
undetectable
4fjpA-6b4oA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-)
no annotation 5 THR D 118
GLY D 126
PRO D 128
ASN D 127
GLY D 228
None
1.23A 4fjpA-6f45D:
undetectable
4fjpA-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f79 -

(-)
no annotation 4 GLY A 115
PRO A 113
ASN A 112
GLY A  41
None
0.82A 4fjpA-6f79A:
undetectable
4fjpA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fht BACTERIOPHYTOCHROME,
ADENYLATE CYCLASE


(Deinococcus
radiodurans;
Synechocystis
sp. PCC 6803)
no annotation 4 GLY A 600
PRO A 602
TYR A 662
GLY A 516
None
0.82A 4fjpA-6fhtA:
undetectable
4fjpA-6fhtA:
13.04