SIMILAR PATTERNS OF AMINO ACIDS FOR 4FGK_A_0TXA302_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7g TYROSINE
PHENOL-LYASE

(Pantoea
agglomerans) 		PF01212
(Beta_elim_lyase) 		4 GLN A 364
PHE A 453
PRO A 362
PHE A 439
 None
 1.20A 4fgkA-1c7gA:
2.7		 4fgkA-1c7gA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3e ALCOHOL
DEHYDROGENASE, CLASS
II

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ILE A  90
PRO A  91
PHE A  92
PHE A 321
 None
 0.94A 4fgkA-1e3eA:
4.0		 4fgkA-1e3eA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5p APHRODISIN

(Mesocricetus
auratus) 		PF00061
(Lipocalin) 		4 PHE A  93
ILE A  87
PRO A  84
PHE A 129
 None
 1.24A 4fgkA-1e5pA:
undetectable		 4fgkA-1e5pA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3g GLUCOSE-SPECIFIC
PHOSPHOCARRIER
PROTEIN IIAGLC

(Escherichia
coli) 		PF00358
(PTS_EIIA_1) 		4 PHE A  91
ILE A  52
PRO A  25
PHE A 122
 None
 1.25A 4fgkA-1f3gA:
undetectable		 4fgkA-1f3gA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gjv [3-METHYL-2-OXOBUTAN
OATE DEHYDROGENASE
[LIPOAMIDE]] KINASE

(Rattus
norvegicus) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 ILE A 200
PRO A 236
PHE A 234
PHE A 232
 None
 1.13A 4fgkA-1gjvA:
undetectable		 4fgkA-1gjvA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltm 36 KDA SOLUBLE LYTIC
TRANSGLYCOSYLASE

(Escherichia
coli) 		PF13406
(SLT_2) 		4 GLN A  61
ILE A  64
PHE A  63
PHE A 183
 None
 1.18A 4fgkA-1ltmA:
undetectable		 4fgkA-1ltmA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n97 CYP175A1

(Thermus
thermophilus) 		PF00067
(p450) 		4 GLN A 244
PHE A 354
PHE A 357
PHE A 353
 None
 1.23A 4fgkA-1n97A:
undetectable		 4fgkA-1n97A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		4 GLN A   4
ILE A   6
PHE A 284
PHE A 290
 None
 0.98A 4fgkA-1oltA:
undetectable		 4fgkA-1oltA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rc6 HYPOTHETICAL PROTEIN
YLBA

(Escherichia
coli) 		PF05899
(Cupin_3)
PF07883
(Cupin_2) 		4 PHE A1076
ILE A1039
PRO A1040
PHE A1119
 None
 1.27A 4fgkA-1rc6A:
undetectable		 4fgkA-1rc6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rvf FAB 17-IA

(Mus musculus) 		PF07686
(V-set) 		4 GLN L  89
PHE L  98
ILE L  96
PRO L  95
 None
 1.17A 4fgkA-1rvfL:
undetectable		 4fgkA-1rvfL:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjq DESIGNED PROTEIN

(-) 		PF02244
(Propep_M14) 		4 ILE A  62
PRO A  63
PHE A  64
PHE A   4
 None
 1.26A 4fgkA-1vjqA:
undetectable		 4fgkA-1vjqA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w18 LEVANSUCRASE

(Gluconacetobacter
diazotrophicus) 		PF02435
(Glyco_hydro_68) 		4 GLN A 260
ILE A 262
PHE A 307
PHE A 305
 None
 1.23A 4fgkA-1w18A:
undetectable		 4fgkA-1w18A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xuv HYPOTHETICAL PROTEIN
MM0500

(Methanosarcina
mazei) 		PF08327
(AHSA1) 		4 GLN A  75
PHE A  85
ILE A  51
PHE A 102
 None
 0.88A 4fgkA-1xuvA:
undetectable		 4fgkA-1xuvA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zjj HYPOTHETICAL PROTEIN
PH1952

(Pyrococcus
horikoshii) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 ILE A  34
PRO A  35
PHE A  36
PHE A   6
 None
 0.89A 4fgkA-1zjjA:
undetectable		 4fgkA-1zjjA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq9 PROBABLE
DIMETHYLADENOSINE
TRANSFERASE

(Homo sapiens) 		PF00398
(RrnaAD) 		4 PHE A 159
ILE A 133
PRO A 130
PHE A 155
 None
SAM  A4000 ( 4.5A)
SAM  A4000 (-4.1A)
None
 1.17A 4fgkA-1zq9A:
undetectable		 4fgkA-1zq9A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2am4 ALPHA-1,3-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Oryctolagus
cuniculus) 		PF03071
(GNT-I) 		4 PHE A 221
ILE A 108
PHE A 224
PHE A 220
 None
 1.23A 4fgkA-2am4A:
undetectable		 4fgkA-2am4A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buk COAT PROTEIN

(unidentified
tobacco
necrosis virus) 		PF03898
(TNV_CP) 		4 GLN A 122
ILE A 118
PRO A 117
PHE A 125
 None
 0.89A 4fgkA-2bukA:
undetectable		 4fgkA-2bukA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvp HYPOTHETICAL PROTEIN
PH1917

(Pyrococcus
horikoshii) 		PF01725
(Ham1p_like) 		4 PHE A 146
ILE A 145
PRO A 144
PHE A 107
 None
 1.25A 4fgkA-2dvpA:
undetectable		 4fgkA-2dvpA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvz PUTATIVE EXPORTED
PROTEIN

(Bordetella
pertussis) 		PF03401
(TctC) 		4 PHE A 229
PRO A 235
PHE A 234
PHE A 130
 None
 1.25A 4fgkA-2dvzA:
undetectable		 4fgkA-2dvzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5v PYRANOSE 2-OXIDASE

(Peniophora sp.
SG) 		PF05199
(GMC_oxred_C) 		4 GLN A 155
PHE A 502
PRO A 543
PHE A 504
 None
 1.18A 4fgkA-2f5vA:
undetectable		 4fgkA-2f5vA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv8 MONOOXYGENASE

(Schizosaccharomyces
pombe) 		PF00743
(FMO-like)
PF13450
(NAD_binding_8) 		4 PHE A 440
ILE A  94
PRO A  93
PHE A 441
 None
 1.25A 4fgkA-2gv8A:
undetectable		 4fgkA-2gv8A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p82 CYSTEINE PROTEASE
ATG4A

(Homo sapiens) 		PF03416
(Peptidase_C54) 		4 GLN A  83
PHE A  55
ILE A 128
PHE A 300
 None
 1.19A 4fgkA-2p82A:
undetectable		 4fgkA-2p82A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhz LETHAL(3)MALIGNANT
BRAIN TUMOR-LIKE
PROTEIN

(Homo sapiens) 		PF02820
(MBT) 		4 PHE A 281
ILE A 247
PRO A 252
PHE A 272
 None
 1.26A 4fgkA-2rhzA:
undetectable		 4fgkA-2rhzA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2u1a U1 SMALL NUCLEAR
RIBONUCLEOPROTEIN A

(Homo sapiens) 		PF00076
(RRM_1) 		4 GLN A  36
PHE A  37
PHE A  34
PHE A  57
 None
 1.18A 4fgkA-2u1aA:
undetectable		 4fgkA-2u1aA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9p REPLICATION PROTEIN
E1

(Deltapapillomavirus
4) 		PF00519
(PPV_E1_C) 		4 PHE A 401
ILE A 398
PHE A 402
PHE A 544
 None
 1.26A 4fgkA-2v9pA:
undetectable		 4fgkA-2v9pA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wk2 CHITINASE A

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 PHE A 293
ILE A 192
PRO A 193
PHE A 281
 None
 1.11A 4fgkA-2wk2A:
undetectable		 4fgkA-2wk2A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 PHE A 209
ILE A 179
PRO A 181
PHE A 242
 None
 1.00A 4fgkA-2ww2A:
undetectable		 4fgkA-2ww2A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yax SULFUR
OXYGENASE/REDUCTASE

(Acidianus
ambivalens) 		PF07682
(SOR) 		4 GLN B 107
PRO B  17
PHE B  20
PHE B  23
 None
 0.97A 4fgkA-2yaxB:
undetectable		 4fgkA-2yaxB:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a7s UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5

(Homo sapiens) 		PF01088
(Peptidase_C12) 		4 PHE A  56
ILE A 216
PHE A 218
PHE A  54
 None
 0.98A 4fgkA-3a7sA:
undetectable		 4fgkA-3a7sA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayr ENDOGLUCANASE

(Piromyces
rhizinflatus) 		PF00150
(Cellulase) 		4 ILE A 225
PRO A 273
PHE A 217
PHE A 215
 None
 1.15A 4fgkA-3ayrA:
undetectable		 4fgkA-3ayrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b3j HISTONE-ARGININE
METHYLTRANSFERASE
CARM1

(Rattus
norvegicus) 		PF06325
(PrmA) 		4 ILE A 373
PRO A 374
PHE A 375
PHE A 377
 None
 0.86A 4fgkA-3b3jA:
undetectable		 4fgkA-3b3jA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b4q UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF11574
(DUF3235) 		4 GLN A 178
PHE A 182
ILE A 179
PHE A 193
 None
 1.21A 4fgkA-3b4qA:
undetectable		 4fgkA-3b4qA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bde MLL5499 PROTEIN

(Mesorhizobium
japonicum) 		PF07876
(Dabb) 		4 GLN A  41
PHE A  55
PHE A  53
PHE A   8
 None
 0.97A 4fgkA-3bdeA:
undetectable		 4fgkA-3bdeA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bm3 PSPGI RESTRICTION
ENDONUCLEASE

(Pyrococcus sp.
GI-H) 		PF09019
(EcoRII-C) 		4 ILE A  55
PRO A  52
PHE A 246
PHE A 192
 None
 1.23A 4fgkA-3bm3A:
undetectable		 4fgkA-3bm3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bs8 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Bacillus
subtilis) 		PF00202
(Aminotran_3) 		4 PHE A 359
ILE A 346
PRO A 347
PHE A 350
 None
 1.07A 4fgkA-3bs8A:
undetectable		 4fgkA-3bs8A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvq NOTI RESTRICTION
ENDONUCLEASE

(Nocardia
otitidiscaviarum) 		PF12183
(NotI) 		4 PHE A 301
ILE A 261
PHE A 303
PHE A  90
 None
 1.14A 4fgkA-3bvqA:
undetectable		 4fgkA-3bvqA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxv SULFUR
OXYGENASE/REDUCTASE

(Acidianus
tengchongensis) 		PF07682
(SOR) 		4 GLN A 107
PRO A  17
PHE A  20
PHE A  23
 None
 1.01A 4fgkA-3bxvA:
undetectable		 4fgkA-3bxvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3co1 MICROTUBULE-ASSOCIAT
ED PROTEIN RP/EB
FAMILY MEMBER 3

(Homo sapiens) 		PF00307
(CH) 		4 GLN A 109
PHE A 105
ILE A 108
PHE A 101
 None
 1.21A 4fgkA-3co1A:
undetectable		 4fgkA-3co1A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd2 SITE-SPECIFIC DNA
ENDONUCLEASE I-MSOI

(Monomastix sp.
OKE-1) 		PF00961
(LAGLIDADG_1) 		4 GLN A  41
ILE A  30
PRO A  31
PHE A 128
 None
 1.04A 4fgkA-3fd2A:
undetectable		 4fgkA-3fd2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd2 SITE-SPECIFIC DNA
ENDONUCLEASE I-MSOI

(Monomastix sp.
OKE-1) 		PF00961
(LAGLIDADG_1) 		4 GLN A 244
ILE A 233
PRO A 234
PHE A 331
 None
 1.15A 4fgkA-3fd2A:
undetectable		 4fgkA-3fd2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdx PUTATIVE FILAMENT
PROTEIN / UNIVERSAL
STRESS PROTEIN F

(Klebsiella
pneumoniae) 		PF00582
(Usp) 		4 ILE A   6
PRO A   5
PHE A  34
PHE A  85
 None
ATP  A 301 (-4.2A)
None
None
 1.24A 4fgkA-3fdxA:
undetectable		 4fgkA-3fdxA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i05 TRYPTOPHANYL-TRNA
SYNTHETASE

(Trypanosoma
brucei) 		PF00579
(tRNA-synt_1b) 		4 ILE A 123
PRO A 124
PHE A 118
PHE A 155
 None
 1.19A 4fgkA-3i05A:
undetectable		 4fgkA-3i05A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		4 PHE W 698
ILE W 695
PRO W 696
PHE W 697
 None
 1.07A 4fgkA-3iylW:
undetectable		 4fgkA-3iylW:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j09 COPPER-EXPORTING
P-TYPE ATPASE A

(Archaeoglobus
fulgidus) 		PF00122
(E1-E2_ATPase)
PF00403
(HMA)
PF00702
(Hydrolase) 		4 PHE A 369
ILE A 136
PRO A 134
PHE A 126
 None
 1.27A 4fgkA-3j09A:
2.9		 4fgkA-3j09A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jup PHENAZINE
BIOSYNTHESIS PROTEIN
A/B

(Burkholderia
lata) 		PF03284
(PHZA_PHZB) 		4 PHE A 128
ILE A  91
PHE A 100
PHE A 130
 None
 1.11A 4fgkA-3jupA:
undetectable		 4fgkA-3jupA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k96 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Coxiella
burnetii) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 GLN A  29
PHE A   4
ILE A   8
PRO A   7
 None
 0.94A 4fgkA-3k96A:
5.9		 4fgkA-3k96A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5k HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 1A

(Homo sapiens) 		PF13419
(HAD_2) 		4 ILE A 107
PRO A 108
PHE A 109
PHE A  13
 None
 0.84A 4fgkA-3l5kA:
2.4		 4fgkA-3l5kA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis) 		no annotation 4 PHE A 345
ILE A 343
PRO A 344
PHE A 367
 None
 1.20A 4fgkA-3ll7A:
2.1		 4fgkA-3ll7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o7o ENDOGLUCANASE

(Thermotoga
maritima) 		PF01670
(Glyco_hydro_12) 		5 PHE A 197
ILE A 157
PRO A 158
PHE A 159
PHE A 140
 None
 1.47A 4fgkA-3o7oA:
undetectable		 4fgkA-3o7oA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob8 BETA-GALACTOSIDASE

(Kluyveromyces
lactis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N) 		4 PHE A 279
ILE A 277
PHE A 244
PHE A 289
 None
 1.27A 4fgkA-3ob8A:
undetectable		 4fgkA-3ob8A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oox PUTATIVE 2OG-FE(II)
OXYGENASE FAMILY
PROTEIN

(Caulobacter
vibrioides) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 PHE A  58
ILE A  79
PRO A  80
PHE A  57
 None
 1.14A 4fgkA-3ooxA:
undetectable		 4fgkA-3ooxA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oxk PUTATIVE HISTIDINE
TRIAD FAMILY PROTEIN

(Entamoeba
histolytica) 		PF01230
(HIT) 		4 PHE A  29
ILE A  15
PRO A  16
PHE A  27
 5GP  A 125 (-4.6A)
None
None
None
 1.20A 4fgkA-3oxkA:
undetectable		 4fgkA-3oxkA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyq DEOXYRIBOSE-PHOSPHAT
E ALDOLASE, PUTATIVE

(Toxoplasma
gondii) 		no annotation 4 PHE A 256
ILE A 243
PRO A 248
PHE A  18
 None
None
SO4  A 287 (-3.6A)
None
 1.26A 4fgkA-3qyqA:
undetectable		 4fgkA-3qyqA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rcm TATD FAMILY
HYDROLASE

(Pseudomonas
putida) 		PF01026
(TatD_DNase) 		4 GLN A  33
PHE A  62
ILE A   4
PHE A 262
 None
 1.14A 4fgkA-3rcmA:
undetectable		 4fgkA-3rcmA:
20.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		4 GLN A 122
ILE A 128
PRO A 129
PHE A 131
 TE7  A   1 ( 4.3A)
None
None
None
 1.02A 4fgkA-3te7A:
38.9		 4fgkA-3te7A:
98.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		5 GLN A 122
PHE A 126
PRO A 129
PHE A 131
PHE A 178
 TE7  A   1 ( 4.3A)
TE7  A   1 (-4.3A)
None
None
TE7  A   1 (-3.6A)
 0.51A 4fgkA-3te7A:
38.9		 4fgkA-3te7A:
98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqu NON-CANONICAL PURINE
NTP PYROPHOSPHATASE

(Coxiella
burnetii) 		PF01725
(Ham1p_like) 		4 PHE A 160
ILE A 159
PRO A 158
PHE A 118
 None
 1.25A 4fgkA-3tquA:
undetectable		 4fgkA-3tquA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		4 PHE A 852
ILE A 841
PRO A 962
PHE A 802
 None
 1.24A 4fgkA-3tsyA:
4.6		 4fgkA-3tsyA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v3t CELL DIVISION GTPASE
FTSZ, DIVERGED

(Clostridium
botulinum) 		PF00091
(Tubulin) 		4 PHE A 123
ILE A  10
PRO A   9
PHE A  92
 None
 1.16A 4fgkA-3v3tA:
5.5		 4fgkA-3v3tA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 GLN A 221
ILE A 172
PRO A 171
PHE A 178
 None
 1.18A 4fgkA-3vr1A:
6.0		 4fgkA-3vr1A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a4z ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		4 PHE A 533
ILE A 519
PRO A 520
PHE A 789
 None
 1.27A 4fgkA-4a4zA:
undetectable		 4fgkA-4a4zA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b99 MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A  90
ILE A  86
PRO A  87
PHE A 130
 None
 1.02A 4fgkA-4b99A:
undetectable		 4fgkA-4b99A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bnq NON-CANONICAL PURINE
NTP PYROPHOSPHATASE

(Staphylococcus
aureus) 		PF01725
(Ham1p_like) 		4 PHE A 155
ILE A 154
PRO A 153
PHE A 115
 None
 1.27A 4fgkA-4bnqA:
undetectable		 4fgkA-4bnqA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buj ANTIVIRAL HELICASE
SKI2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT) 		4 PHE A 533
ILE A 519
PRO A 520
PHE A 789
 None
 1.21A 4fgkA-4bujA:
undetectable		 4fgkA-4bujA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzz NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 PHE A  97
PRO A  99
PHE A 446
PHE A 422
 None
 1.26A 4fgkA-4hzzA:
undetectable		 4fgkA-4hzzA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m46 LUCIFERASE

(Lampyris
turkestanicus) 		PF00501
(AMP-binding) 		4 ILE A 241
PRO A 242
PHE A 243
PHE A  89
 None
 0.92A 4fgkA-4m46A:
3.4		 4fgkA-4m46A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qk3 CARBONIC ANHYDRASE 2

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 GLN A  28
ILE A  22
PRO A  21
PHE A  20
 None
 1.12A 4fgkA-4qk3A:
undetectable		 4fgkA-4qk3A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3i YTH
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF04146
(YTH) 		4 PHE A 455
ILE A 473
PRO A 470
PHE A 409
 None
U  B   5 ( 3.8A)
None
None
 1.17A 4fgkA-4r3iA:
undetectable		 4fgkA-4r3iA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcm METHYLATED
RNA-BINDING PROTEIN
1

(Saccharomyces
cerevisiae) 		PF04146
(YTH) 		4 PHE A 203
ILE A 247
PHE A 201
PHE A 157
 None
 1.21A 4fgkA-4rcmA:
undetectable		 4fgkA-4rcmA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rph UDP-GALACTOPYRANOSE
MUTASE

(Mycobacterium
tuberculosis) 		no annotation 4 GLN B 276
ILE B 312
PHE B 296
PHE B 299
 None
 1.13A 4fgkA-4rphB:
undetectable		 4fgkA-4rphB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufs LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 PHE A 288
ILE A 293
PRO A 292
PHE A 264
 None
 1.27A 4fgkA-4ufsA:
undetectable		 4fgkA-4ufsA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcj POLYSACCHARIDE
DEACETYLASE

(Ammonifex
degensii) 		PF01522
(Polysacc_deac_1) 		4 ILE A 133
PRO A 134
PHE A 135
PHE A 113
 None
 0.95A 4fgkA-4wcjA:
undetectable		 4fgkA-4wcjA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqm TOLUENE-4-MONOOXYGEN
ASE ELECTRON
TRANSFER COMPONENT

(Pseudomonas
mendocina) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 PHE A 326
ILE A 302
PRO A 298
PHE A 325
 None
None
None
FAD  A 402 (-3.3A)
 0.88A 4fgkA-4wqmA:
3.0		 4fgkA-4wqmA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcq TUBZ

(Clostridium
phage c-st) 		PF00091
(Tubulin) 		4 PHE A 123
ILE A  10
PRO A   9
PHE A  92
 None
 1.11A 4fgkA-4xcqA:
5.6		 4fgkA-4xcqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xd0 TDP-3-AMINOQUINOVOSE
-N-FORMYLTRANSFERASE

(Providencia
alcalifaciens) 		PF00551
(Formyl_trans_N)
PF12796
(Ank_2) 		4 GLN A  43
PHE A  42
ILE A 156
PHE A 218
 None
None
None
T3F  A 403 (-4.0A)
 1.24A 4fgkA-4xd0A:
3.5		 4fgkA-4xd0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zsl MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A  90
ILE A  86
PRO A  87
PHE A 130
 None
4QZ  A 401 (-4.4A)
None
None
 1.09A 4fgkA-4zslA:
undetectable		 4fgkA-4zslA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zuz SIDC

(Legionella
pneumophila) 		no annotation 4 GLN A 334
PRO A 331
PHE A 332
PHE A 394
 None
 0.97A 4fgkA-4zuzA:
undetectable		 4fgkA-4zuzA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8d CARBOHYDRATE BINDING
FAMILY 6

(Ruminiclostridium
thermocellum) 		PF04616
(Glyco_hydro_43) 		4 ILE A  35
PRO A  34
PHE A  36
PHE A 165
 None
 1.12A 4fgkA-5a8dA:
undetectable		 4fgkA-5a8dA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 PHE A 283
ILE A 182
PRO A 183
PHE A 271
 None
 1.04A 4fgkA-5df0A:
undetectable		 4fgkA-5df0A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT

(Azospira oryzae) 		PF13247
(Fer4_11) 		4 GLN B 174
PHE B 187
ILE B  78
PRO B  79
 None
 1.12A 4fgkA-5e7oB:
undetectable		 4fgkA-5e7oB:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpr CHITINASE

(Ostrinia
furnacalis) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 PHE A 286
ILE A 185
PRO A 186
PHE A 274
 PHE  A 286 ( 1.3A)
ILE  A 185 ( 0.7A)
PRO  A 186 ( 1.1A)
PHE  A 274 ( 1.3A)
 1.11A 4fgkA-5gprA:
undetectable		 4fgkA-5gprA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxf 3C PROTEASE

(Enterovirus A) 		PF00548
(Peptidase_C3) 		4 PHE A  90
ILE A  91
PRO A  92
PHE A   7
 None
 1.10A 4fgkA-5hxfA:
undetectable		 4fgkA-5hxfA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyv LUCIFERIN
4-MONOOXYGENASE

(Photinus
pyralis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ILE A 241
PRO A 242
PHE A 243
PHE A  89
 None
 1.06A 4fgkA-5kyvA:
4.1		 4fgkA-5kyvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 2

(Sus scrofa) 		no annotation 4 GLN A 665
PHE A 657
PHE A 652
PHE A 675
 None
 1.21A 4fgkA-5mpmA:
2.0		 4fgkA-5mpmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mw5 PROTEIN JAGGED-2

(Homo sapiens) 		PF01414
(DSL)
PF07657
(MNNL) 		4 ILE A 132
PRO A 133
PHE A 134
PHE A 136
 None
 1.04A 4fgkA-5mw5A:
undetectable		 4fgkA-5mw5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0s GLUCOSYLCERAMIDASE

(Thermoanaerobacterium
xylanolyticum) 		PF04685
(DUF608)
PF12215
(Glyco_hydr_116N)
PF17168
(DUF5127) 		4 PHE A 195
PRO A 335
PHE A 336
PHE A 111
 None
 1.15A 4fgkA-5o0sA:
undetectable		 4fgkA-5o0sA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v2d DIOXYGENASE

(Pseudomonas
brassicacearum) 		no annotation 4 ILE A   3
PRO A   4
PHE A   5
PHE A  11
 None
 1.15A 4fgkA-5v2dA:
undetectable		 4fgkA-5v2dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE

(Sphingobium sp.
SYK-6) 		PF04909
(Amidohydro_2) 		4 GLN A 100
PHE A 108
ILE A  97
PRO A 110
 None
 1.08A 4fgkA-5vn5A:
undetectable		 4fgkA-5vn5A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5y RNA POLYMERASE
I-SPECIFIC
TRANSCRIPTION
INITIATION FACTOR
RRN6

(Saccharomyces
cerevisiae) 		PF10214
(Rrn6) 		4 GLN O 454
ILE O 511
PHE O 537
PHE O 467
 None
 1.27A 4fgkA-5w5yO:
undetectable		 4fgkA-5w5yO:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x06 DNAA REGULATORY
INACTIVATOR HDA

(Escherichia
coli) 		no annotation 4 GLN E  35
PHE E  19
PRO E  24
PHE E  22
 None
None
None
ADP  E1001 (-3.3A)
 1.25A 4fgkA-5x06E:
undetectable		 4fgkA-5x06E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y81 ACTIN-RELATED
PROTEIN 4

(Saccharomyces
cerevisiae) 		no annotation 4 PHE F 238
ILE F 204
PRO F 205
PHE F 239
 None
 0.91A 4fgkA-5y81F:
undetectable		 4fgkA-5y81F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ykn PROBABLE
LYSINE-SPECIFIC
DEMETHYLASE JMJ14

(Arabidopsis
thaliana) 		no annotation 4 GLN A 116
PHE A 171
ILE A 118
PHE A 169
 None
 1.20A 4fgkA-5yknA:
undetectable		 4fgkA-5yknA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zl9 CHITINASE AB

(Serratia
marcescens) 		no annotation 4 PHE A 293
ILE A 192
PRO A 193
PHE A 281
 None
 1.13A 4fgkA-5zl9A:
undetectable		 4fgkA-5zl9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE

(Plasmodium
vivax) 		no annotation 4 PHE A 202
ILE A 221
PHE A 205
PHE A 201
 None
 1.05A 4fgkA-6bpcA:
undetectable		 4fgkA-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btp -

(-) 		no annotation 4 ILE A  15
PRO A  16
PHE A  17
PHE A  58
 None
 1.00A 4fgkA-6btpA:
undetectable		 4fgkA-6btpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqb CHALCONE SYNTHASE

(Piper
methysticum) 		no annotation 4 PHE A 266
ILE A 255
PRO A 376
PHE A 216
 None
 1.21A 4fgkA-6cqbA:
undetectable		 4fgkA-6cqbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0s TBC1 DOMAIN FAMILY
MEMBER 22B

(Homo sapiens) 		no annotation 4 GLN A 284
PRO A 280
PHE A 282
PHE A 291
 None
 1.27A 4fgkA-6d0sA:
undetectable		 4fgkA-6d0sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d2l HISTONE-ARGININE
METHYLTRANSFERASE
CARM1

(Homo sapiens) 		no annotation 4 ILE A 372
PRO A 373
PHE A 374
PHE A 376
 None
 0.96A 4fgkA-6d2lA:
undetectable		 4fgkA-6d2lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dm8 -

(-) 		no annotation 4 PHE A 299
ILE A 245
PHE A 296
PHE A 300
 None
 1.27A 4fgkA-6dm8A:
undetectable		 4fgkA-6dm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5
NADH DEHYDROGENASE
[UBIQUINONE] 1 BETA
SUBCOMPLEX SUBUNIT 7

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 PHE o  76
ILE L 472
PRO L 473
PHE L  55
 None
 1.27A 4fgkA-6g2jo:
undetectable		 4fgkA-6g2jo:
undetectable