SIMILAR PATTERNS OF AMINO ACIDS FOR 4F4D_B_CHDB505_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a9n | U2A' (Homo sapiens) |
PF14580(LRR_9) | 5 | LEU A 109LEU A 118LEU A 145ILE A 79VAL A 125 | None | 1.24A | 4f4dB-1a9nA:undetectable | 4f4dB-1a9nA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1djp | GLUTAMINASE-ASPARAGINASE (Pseudomonas sp.7A) |
PF00710(Asparaginase) | 5 | LEU A1110LEU A1075ILE A1094THR A1102VAL A1062 | None | 1.23A | 4f4dB-1djpA:4.4 | 4f4dB-1djpA:20.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 7 | LEU A 68ARG A 87LYS A 90SER A 169HIS A 235VAL A 277TRP A 282 | None | 1.40A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 7 | LEU A 68ARG A 87LYS A 90THR A 170HIS A 235VAL A 277TRP A 282 | None | 1.21A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 9 | MET A 46LEU A 59ARG A 87LYS A 90ILE A 91SER A 169HIS A 235VAL A 277TRP A 282 | None | 0.90A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 9 | MET A 46LEU A 59ARG A 87LYS A 90ILE A 91THR A 170HIS A 235VAL A 277TRP A 282 | None | 0.73A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 9 | MET A 46LEU A 59LEU A 62LYS A 90ILE A 91SER A 169HIS A 235VAL A 277TRP A 282 | None | 0.88A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lbq | FERROCHELATASE (Saccharomycescerevisiae) |
PF00762(Ferrochelatase) | 9 | MET A 46LEU A 59LEU A 62LYS A 90ILE A 91THR A 170HIS A 235VAL A 277TRP A 282 | None | 0.70A | 4f4dB-1lbqA:48.3 | 4f4dB-1lbqA:49.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lns | X-PROLYL DIPEPTIDYLAMINOPEPTIDASE (Lactococcuslactis) |
PF02129(Peptidase_S15)PF08530(PepX_C)PF09168(PepX_N) | 5 | LEU A 637LEU A 680ILE A 727THR A 472HIS A 735 | None | 1.12A | 4f4dB-1lnsA:1.9 | 4f4dB-1lnsA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozn | RETICULON 4 RECEPTOR (Homo sapiens) |
PF13855(LRR_8) | 5 | LEU A 83LEU A 107LEU A 129ILE A 62VAL A 72 | None | 1.09A | 4f4dB-1oznA:undetectable | 4f4dB-1oznA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozn | RETICULON 4 RECEPTOR (Homo sapiens) |
PF13855(LRR_8) | 5 | LEU A 112LEU A 137LEU A 159ILE A 96THR A 173 | None | 1.22A | 4f4dB-1oznA:undetectable | 4f4dB-1oznA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q15 | CARA (Pectobacteriumcarotovorum) |
PF00733(Asn_synthase)PF09147(DUF1933) | 5 | LEU A 92LEU A 88LEU A 84ARG A 91THR A 63 | None | 1.06A | 4f4dB-1q15A:2.2 | 4f4dB-1q15A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhg | ATP-DEPENDENTHELICASE PCRA (Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | LEU A 617LEU A 577LEU A 564ILE A 321VAL A 299 | None | 1.20A | 4f4dB-1qhgA:2.4 | 4f4dB-1qhgA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhh | PROTEIN (PCRA(SUBUNIT))PROTEIN (PCRA(SUBUNIT)) (Geobacillusstearothermophilus;Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C)PF13361(UvrD_C) | 5 | LEU D 617LEU D 577LEU D 564ILE B 321VAL B 299 | None | 1.18A | 4f4dB-1qhhD:undetectable | 4f4dB-1qhhD:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhy | IMIDAZOLE GLYCEROLPHOSPHATEDEHYDRATASE (Cryptococcusneoformans) |
PF00475(IGPD) | 5 | LEU A 144LEU A 145LEU A 126SER A 160VAL A 133 | None | 1.14A | 4f4dB-1rhyA:undetectable | 4f4dB-1rhyA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 41 KDASUBUNITACTIVATOR 1 40 KDASUBUNIT (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00004(AAA)PF08542(Rep_fac_C)PF13177(DNA_pol3_delta2) | 5 | LEU D 347LEU D 343LEU D 333ILE D 271SER E 175 | None | 1.13A | 4f4dB-1sxjD:undetectable | 4f4dB-1sxjD:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbr | CONSERVEDHYPOTHETICAL PROTEIN (Porphyromonasgingivalis) |
PF04371(PAD_porph) | 5 | LEU A 281LEU A 328LEU A 321ILE A 283TRP A 20 | None | 1.18A | 4f4dB-1zbrA:undetectable | 4f4dB-1zbrA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaa | ALPHA-AMYLASE (Aspergillusniger) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 5 | LEU A 100LEU A 103LEU A 107ILE A 65TRP A 6 | None | 0.94A | 4f4dB-2aaaA:undetectable | 4f4dB-2aaaA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayx | SENSOR KINASEPROTEIN RCSC (Escherichiacoli) |
PF00072(Response_reg)PF09456(RcsC) | 5 | LEU A 936LEU A 847ILE A 900SER A 846VAL A 927 | None | 1.25A | 4f4dB-2ayxA:3.1 | 4f4dB-2ayxA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkk | CYTOCHROME P450 (Streptomycescoelicolor) |
PF00067(p450) | 6 | LEU A 266LEU A 260LEU A 257ARG A 263ILE A 337TRP A 391 | None | 1.29A | 4f4dB-2dkkA:undetectable | 4f4dB-2dkkA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8b | PROBABLEMOLYBDOPTERIN-GUANINE DINUCLEOTIDEBIOSYNTHESIS PROTEINA (Aquifexaeolicus) |
PF12804(NTP_transf_3) | 5 | LEU A 163LEU A 164LEU A 134ILE A 149VAL A 102 | None | 1.24A | 4f4dB-2e8bA:2.3 | 4f4dB-2e8bA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fv2 | RCD1 REQUIRED FORCELLDIFFERENTIATION1HOMOLOG (Homo sapiens) |
PF04078(Rcd1) | 5 | LEU A 51LEU A 50LEU A 23ILE A 99SER A 27 | None | 1.25A | 4f4dB-2fv2A:undetectable | 4f4dB-2fv2A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2go4 | UDP-3-O-[3-HYDROXYMYRISTOYL]N-ACETYLGLUCOSAMINEDEACETYLASE (Aquifexaeolicus) |
PF03331(LpxC) | 5 | LEU A 250LEU A 247LEU A 243THR A 156VAL A 138 | None | 0.98A | 4f4dB-2go4A:undetectable | 4f4dB-2go4A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | LEU A 420LEU A 456LEU A 274VAL A 292TRP A 289 | None | 1.23A | 4f4dB-2h2qA:2.2 | 4f4dB-2h2qA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk0 | D-PSICOSE3-EPIMERASE (Agrobacteriumtumefaciens) |
PF01261(AP_endonuc_2) | 5 | LEU A 62LEU A 99LEU A 48ILE A 33SER A 44 | LEU A 62 ( 0.6A)LEU A 99 ( 0.6A)LEU A 48 ( 0.6A)ILE A 33 ( 0.7A)SER A 44 ( 0.0A) | 1.17A | 4f4dB-2hk0A:undetectable | 4f4dB-2hk0A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgr | YEGS (Escherichiacoli) |
PF00781(DAGK_cat) | 5 | LEU A 91LEU A 93SER A 15THR A 16VAL A 73 | None | 1.24A | 4f4dB-2jgrA:5.9 | 4f4dB-2jgrA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omv | INTERNALIN-A (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | LEU A 404LEU A 401ILE A 385SER A 374VAL A 357 | None | 1.25A | 4f4dB-2omvA:undetectable | 4f4dB-2omvA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdf | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Escherichiacoli) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 5 | LEU A 513LEU A 514LEU A 482SER A 478THR A 558 | None | 1.20A | 4f4dB-2xdfA:undetectable | 4f4dB-2xdfA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhe | UNC18 (Monosigabrevicollis) |
PF00995(Sec1) | 5 | LEU A 171LEU A 168LEU A 164THR A 191VAL A 575 | None | 1.22A | 4f4dB-2xheA:3.4 | 4f4dB-2xheA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 5 | LEU A 691LEU A 669ILE A 653THR A 663VAL A 634 | None | 1.22A | 4f4dB-2yhgA:3.1 | 4f4dB-2yhgA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 5 | LEU A 240LEU A 241LEU A 215ILE A 96SER A 112 | HEM A 413 ( 4.5A)HEM A 413 (-4.5A)NoneHEM A 413 (-4.0A)None | 1.24A | 4f4dB-2zbzA:undetectable | 4f4dB-2zbzA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zii | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 74 (Saccharomycescerevisiae) |
PF05719(GPP34) | 5 | LEU A 265LEU A 269LEU A 272ILE A 256VAL A 306 | None | 1.22A | 4f4dB-2ziiA:undetectable | 4f4dB-2ziiA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zvw | PROLIFERATING CELLNUCLEAR ANTIGEN 2 (Arabidopsisthaliana) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU A 79LEU A 16LEU A 72ILE A 88VAL A 99 | None | 0.98A | 4f4dB-2zvwA:undetectable | 4f4dB-2zvwA:19.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3aqi | FERROCHELATASE (Homo sapiens) |
PF00762(Ferrochelatase) | 9 | LEU A 89LEU A 92LEU A 98ILE A 119SER A 197THR A 198HIS A 263VAL A 305TRP A 310 | NoneCHD A 1 (-4.8A)CHD A 1 (-4.3A)NoneCHD A 1 (-3.0A)NoneCHD A 1 (-4.3A)CHD A 1 ( 4.9A)CHD A 2 (-4.7A) | 0.45A | 4f4dB-3aqiA:60.7 | 4f4dB-3aqiA:99.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3aqi | FERROCHELATASE (Homo sapiens) |
PF00762(Ferrochelatase) | 8 | LEU A 89LEU A 92LEU A 98LYS A 118ILE A 119SER A 197VAL A 305TRP A 310 | NoneCHD A 1 (-4.8A)CHD A 1 (-4.3A)NoneNoneCHD A 1 (-3.0A)CHD A 1 ( 4.9A)CHD A 2 (-4.7A) | 0.93A | 4f4dB-3aqiA:60.7 | 4f4dB-3aqiA:99.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayf | NITRIC OXIDEREDUCTASE (Geobacillusstearothermophilus) |
PF00115(COX1) | 5 | LEU A 473LEU A 469ILE A 374SER A 537THR A 534 | None | 1.25A | 4f4dB-3ayfA:undetectable | 4f4dB-3ayfA:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwk | PENICILLIN-BINDINGPROTEIN 2 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF00912(Transgly) | 5 | LEU A 404LEU A 400LEU A 508ILE A 490SER A 504 | None | 0.92A | 4f4dB-3dwkA:undetectable | 4f4dB-3dwkA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egl | DEGV FAMILY PROTEIN (Corynebacteriumglutamicum) |
PF02645(DegV) | 5 | LEU A 221LEU A 192LEU A 195ILE A 209VAL A 205 | NoneMLY A 191 ( 4.5A)MLY A 191 ( 3.7A)NoneNone | 1.25A | 4f4dB-3eglA:2.5 | 4f4dB-3eglA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fqd | 5'-3'EXORIBONUCLEASE 2 (Schizosaccharomycespombe) |
PF03159(XRN_N) | 5 | LEU A 691LEU A 688LEU A 743ILE A 699SER A 748 | None | 1.11A | 4f4dB-3fqdA:2.7 | 4f4dB-3fqdA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1z | PUTATIVE LYSYL-TRNASYNTHETASE (Salmonellaenterica) |
PF00152(tRNA-synt_2) | 5 | LEU A 134LEU A 127ILE A 26SER A 295VAL A 35 | None | 1.24A | 4f4dB-3g1zA:undetectable | 4f4dB-3g1zA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7u | ALDO-KETO REDUCTASE (Arabidopsisthaliana) |
PF00248(Aldo_ket_red) | 5 | LEU A 65LEU A 62LEU A 103SER A 80THR A 79 | None | 1.07A | 4f4dB-3h7uA:undetectable | 4f4dB-3h7uA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7u | ALDO-KETO REDUCTASE (Arabidopsisthaliana) |
PF00248(Aldo_ket_red) | 5 | LEU A 65LEU A 103SER A 80THR A 79VAL A 31 | None | 1.19A | 4f4dB-3h7uA:undetectable | 4f4dB-3h7uA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htv | D-ALLOSE KINASE (Escherichiacoli) |
PF00480(ROK) | 5 | LEU A 106LEU A 102LEU A 98ILE A 53VAL A 40 | None | 1.16A | 4f4dB-3htvA:undetectable | 4f4dB-3htvA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kv0 | HET-C2 (Podosporaanserina) |
PF08718(GLTP) | 5 | MET A 67LEU A 197ILE A 88THR A 49VAL A 26 | NoneMLY A 198 ( 4.3A)NoneMLY A 64 ( 4.3A)None | 1.19A | 4f4dB-3kv0A:undetectable | 4f4dB-3kv0A:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll9 | ISOPENTENYLPHOSPHATE KINASE (Methanothermobacterthermautotrophicus) |
PF00696(AA_kinase) | 5 | LEU A 160ILE A 155SER A 9THR A 12HIS A 52 | NoneNoneADP A 267 (-2.7A)NoneNone | 1.23A | 4f4dB-3ll9A:3.1 | 4f4dB-3ll9A:24.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ly1 | PUTATIVEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Pectobacteriumatrosepticum) |
PF00155(Aminotran_1_2) | 5 | LEU A 323LEU A 320LEU A 317ILE A 394SER A 330 | None | 1.03A | 4f4dB-3ly1A:undetectable | 4f4dB-3ly1A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne5 | CATION EFFLUX SYSTEMPROTEIN CUSA (Escherichiacoli) |
PF00873(ACR_tran) | 5 | MET A 696LEU A 840ILE A 826SER A 855THR A 854 | None | 1.24A | 4f4dB-3ne5A:undetectable | 4f4dB-3ne5A:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyq | MALONYL-COA LIGASE (Streptomycescoelicolor) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 160LEU A 167ILE A 155SER A 294THR A 293 | None | 1.07A | 4f4dB-3nyqA:undetectable | 4f4dB-3nyqA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2j | DIPEPTIDASE (Streptomycescoelicolor) |
PF01244(Peptidase_M19) | 6 | LEU A 357LEU A 354LEU A 345ILE A 317SER A 3VAL A 296 | None | 1.30A | 4f4dB-3s2jA:undetectable | 4f4dB-3s2jA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqz | PUTATIVEHYDROXYMETHYLGLUTARYL-COA SYNTHASE (Streptococcusmutans) |
PF00195(Chal_sti_synt_N)PF08540(HMG_CoA_synt_C) | 5 | LEU A 290LEU A 287LEU A 284ILE A 168THR A 11 | NoneNoneNoneNoneGOL A 392 (-4.2A) | 1.24A | 4f4dB-3sqzA:undetectable | 4f4dB-3sqzA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1l | CRISPR SYSTEM CMRSUBUNIT CMR5 (Archaeoglobusfulgidus) |
PF09701(Cas_Cmr5) | 5 | LEU F 111LEU F 98LEU F 94ILE F 131THR F 54 | None | 1.06A | 4f4dB-3x1lF:undetectable | 4f4dB-3x1lF:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwp | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN-3 (Drosophilamelanogaster) |
no annotation | 5 | LEU A 599LEU A 596LEU A 593ILE A 554THR A 648 | None | 0.95A | 4f4dB-4bwpA:undetectable | 4f4dB-4bwpA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzi | SEC23P (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | LEU A 241LEU A 245LEU A 137SER A 132THR A 131 | None | 1.17A | 4f4dB-4bziA:3.2 | 4f4dB-4bziA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 5 | LEU A 342LEU A 365LEU A 386ILE A 322VAL A 358 | None | 1.23A | 4f4dB-4cp6A:undetectable | 4f4dB-4cp6A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cs5 | PROLIFERATING CELLNUCLEAR ANTIGEN (Litopenaeusvannamei) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU A 79LEU A 16LEU A 72ILE A 88VAL A 99 | None | 1.12A | 4f4dB-4cs5A:undetectable | 4f4dB-4cs5A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dmg | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA1493 (Thermusthermophilus) |
PF02475(Met_10) | 5 | LEU A 305LEU A 331ARG A 303SER A 328THR A 290 | None | 1.13A | 4f4dB-4dmgA:undetectable | 4f4dB-4dmgA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eze | HALOACIDDEHALOGENASE-LIKEHYDROLASE (Salmonellaenterica) |
PF12710(HAD) | 5 | LEU A 211LEU A 141SER A 113THR A 117VAL A 152 | None | 1.18A | 4f4dB-4ezeA:undetectable | 4f4dB-4ezeA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | LEU A 298LEU A 319LEU A 342ILE A 278VAL A 308 | None | 0.99A | 4f4dB-4fs7A:undetectable | 4f4dB-4fs7A:24.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwi | ABC-TYPEDIPEPTIDE/OLIGOPEPTIDE/NICKEL TRANSPORTSYSTEM, ATPASECOMPONENT (Caldanaerobactersubterraneus) |
PF00005(ABC_tran)PF08352(oligo_HPY) | 5 | MET B 139LEU B 197LEU B 200ILE B 193VAL B 95 | None | 1.18A | 4f4dB-4fwiB:undetectable | 4f4dB-4fwiB:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lxr | PROTEIN TOLL (Drosophilamelanogaster) |
PF00560(LRR_1)PF01462(LRRNT)PF13306(LRR_5)PF13855(LRR_8) | 5 | LEU A 349LEU A 354ILE A 344SER A 332THR A 309 | None | 1.11A | 4f4dB-4lxrA:undetectable | 4f4dB-4lxrA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mag | SIALIC ACID BINDINGPROTEIN (Vibrio cholerae) |
PF03480(DctP) | 5 | LEU A 27LEU A 37LEU A 39ILE A 232VAL A 214 | None | 1.18A | 4f4dB-4magA:undetectable | 4f4dB-4magA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mct | KILLER PROTEIN (Proteusvulgaris) |
PF05015(HigB-like_toxin) | 5 | LEU B 86LEU B 10ILE B 2SER B 20THR B 19 | None | 1.11A | 4f4dB-4mctB:undetectable | 4f4dB-4mctB:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | BRASSINOSTEROIDINSENSITIVE1-ASSOCIATEDRECEPTOR KINASE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU B 121LEU B 145LEU B 166SER B 185THR B 161 | None | 1.20A | 4f4dB-4mn8B:undetectable | 4f4dB-4mn8B:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nh0 | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 5 | LEU A1232LEU A1240LEU A1208ILE A1259VAL A1212 | None | 1.25A | 4f4dB-4nh0A:undetectable | 4f4dB-4nh0A:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovd | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Atopobiumparvulum) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | LEU A 296LEU A 541ILE A 432SER A 551VAL A 306 | None | 1.14A | 4f4dB-4ovdA:undetectable | 4f4dB-4ovdA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p42 | EXTENDEDSYNAPTOTAGMIN-2 (Homo sapiens) |
PF00168(C2)PF17047(SMP_LBD) | 5 | LEU A 430LEU A 369ILE A 390SER A 407TRP A 460 | None | 1.24A | 4f4dB-4p42A:undetectable | 4f4dB-4p42A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pbc | D-AMINO ACIDAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01063(Aminotran_4) | 5 | LEU A 71LEU A 74LEU A 78ILE A 96THR A 119 | None | 1.14A | 4f4dB-4pbcA:undetectable | 4f4dB-4pbcA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q62 | LEUCINE-RICHREPEAT-AND COILEDCOIL-CONTAININGPROTEIN (Legionellapneumophila) |
PF13855(LRR_8) | 5 | LEU A 287LEU A 311LEU A 363ILE A 277THR A 356 | None | 1.19A | 4f4dB-4q62A:undetectable | 4f4dB-4q62A:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s38 | 4-HYDROXY-3-METHYLBUT-2-EN-1-YLDIPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF04551(GcpE) | 5 | LEU A 251LEU A 247LEU A 211ILE A 24THR A 231 | None | 1.10A | 4f4dB-4s38A:undetectable | 4f4dB-4s38A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u48 | PUTATIVE INNERMEMBRANE LIPOPROTEIN (Salmonellaenterica) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF10569(Thiol-ester_cl)PF11974(MG1) | 5 | LEU A 802LEU A 767LEU A 754ILE A 793VAL A 750 | None | 1.12A | 4f4dB-4u48A:undetectable | 4f4dB-4u48A:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wpe | CYTOKINESIS PROTEIN2 (Saccharomycescerevisiae) |
PF00611(FCH) | 5 | LEU A 21LEU A 20LYS A 122ILE A 123SER A 4 | None | 1.23A | 4f4dB-4wpeA:undetectable | 4f4dB-4wpeA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yu4 | HEMOGLOBIN (Helogaleparvula) |
PF00042(Globin) | 5 | LEU A 73LEU A 76ILE A 10SER A 138THR A 137 | None | 1.04A | 4f4dB-4yu4A:undetectable | 4f4dB-4yu4A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z79 | LEIOMODIN-1ACTIN-BINDING SITE 2(ABS2) (Homo sapiens) |
no annotation | 5 | LEU A 420LEU A 450LEU A 467ILE A 407THR A 462 | NoneNoneNoneNoneGOL A 504 (-3.5A) | 1.10A | 4f4dB-4z79A:undetectable | 4f4dB-4z79A:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8g | TROPOMODULIN-1,LEIOMODIN-1 CHIMERA(TP1 ABS2) (Homo sapiens) |
no annotation | 5 | LEU A 420LEU A 450LEU A 467ILE A 407THR A 462 | None | 1.08A | 4f4dB-4z8gA:undetectable | 4f4dB-4z8gA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z94 | GELSOLIN,TROPOMODULIN-1,LEIOMODIN-1 CHIMERA (Homo sapiens) |
PF00626(Gelsolin) | 5 | LEU G1420LEU G1450LEU G1467ILE G1407THR G1462 | None | 1.06A | 4f4dB-4z94G:2.4 | 4f4dB-4z94G:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zad | FDC1 (Candidadubliniensis) |
PF01977(UbiD) | 5 | LEU A 378LEU A 381ILE A 373HIS A 348VAL A 392 | None | 1.22A | 4f4dB-4zadA:undetectable | 4f4dB-4zadA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoy | SQT1 (Chaetomiumthermophilum) |
PF00400(WD40) | 5 | LEU A 328LEU A 254ILE A 325THR A 285VAL A 305 | None | 1.20A | 4f4dB-4zoyA:undetectable | 4f4dB-4zoyA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | LEU A 267LEU A 291LEU A 320ILE A 251THR A 315 | None | 1.11A | 4f4dB-4ztxA:undetectable | 4f4dB-4ztxA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bw4 | 16S RRNA(ADENINE(1408)-N(1))-METHYLTRANSFERASE (Catenulisporaacidiphila) |
no annotation | 5 | LEU A 117LEU A 128ARG A 118ILE A 158THR A 175 | None | 1.24A | 4f4dB-5bw4A:2.2 | 4f4dB-5bw4A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fms | INTRAFLAGELLARTRANSPORT PROTEIN 52HOMOLOG (Mus musculus) |
PF09822(ABC_transp_aux) | 5 | LEU A 28LEU A 225ARG A 33ILE A 38SER A 231 | None | 1.22A | 4f4dB-5fmsA:undetectable | 4f4dB-5fmsA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g4i | PHOSPHOLYASE (Paenarthrobacteraurescens) |
PF00202(Aminotran_3) | 5 | LEU A 428LEU A 431LEU A 435ILE A 345THR A 387 | None | 0.84A | 4f4dB-5g4iA:undetectable | 4f4dB-5g4iA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g4i | PHOSPHOLYASE (Paenarthrobacteraurescens) |
PF00202(Aminotran_3) | 5 | LEU A 428LEU A 431LEU A 435THR A 387VAL A 362 | None | 1.09A | 4f4dB-5g4iA:undetectable | 4f4dB-5g4iA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jh1 | ALDOSE REDUCTASE,AKR4C7 (Zea mays) |
PF00248(Aldo_ket_red) | 5 | LEU A 62LEU A 59LEU A 100SER A 77THR A 76 | None | 1.08A | 4f4dB-5jh1A:undetectable | 4f4dB-5jh1A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jh1 | ALDOSE REDUCTASE,AKR4C7 (Zea mays) |
PF00248(Aldo_ket_red) | 5 | LEU A 62LEU A 100SER A 77THR A 76VAL A 28 | None | 1.23A | 4f4dB-5jh1A:undetectable | 4f4dB-5jh1A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lfn | CHONDROADHERIN (Homo sapiens) |
PF00560(LRR_1)PF01462(LRRNT)PF13855(LRR_8) | 5 | LEU A 251LEU A 275LEU A 295ILE A 234VAL A 267 | None | 0.98A | 4f4dB-5lfnA:undetectable | 4f4dB-5lfnA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mea | CELL DIVISION CYCLEPROTEIN CDT1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 381LEU A 340LEU A 344ILE A 430SER A 348 | None | 1.17A | 4f4dB-5meaA:undetectable | 4f4dB-5meaA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mtz | RIBONUCLEASE Z (Saccharomycescerevisiae) |
PF13691(Lactamase_B_4) | 5 | LEU A 84LEU A 86LEU A 93ILE A 76VAL A 104 | None | 1.13A | 4f4dB-5mtzA:undetectable | 4f4dB-5mtzA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n72 | WIPA (Legionellapneumophila) |
no annotation | 5 | MET A 336LEU A 362LEU A 340ILE A 275VAL A 307 | None | 1.22A | 4f4dB-5n72A:undetectable | 4f4dB-5n72A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0l | RETICULON-4 RECEPTOR (Mus musculus) |
no annotation | 5 | LEU A 83LEU A 107LEU A 129ILE A 62VAL A 72 | None | 1.08A | 4f4dB-5o0lA:undetectable | 4f4dB-5o0lA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0l | RETICULON-4 RECEPTOR (Mus musculus) |
no annotation | 5 | LEU A 112LEU A 137LEU A 159ILE A 96THR A 173 | None | 1.22A | 4f4dB-5o0lA:undetectable | 4f4dB-5o0lA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5of4 | TFIIH BASALTRANSCRIPTION FACTORCOMPLEX HELICASE XPDSUBUNIT (Homo sapiens) |
PF06733(DEAD_2)PF06777(HBB)PF13307(Helicase_C_2) | 5 | LEU B 567LEU B 597ILE B 561SER B 541THR B 540 | None | 1.13A | 4f4dB-5of4B:undetectable | 4f4dB-5of4B:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tnv | AP ENDONUCLEASE,FAMILY PROTEIN 2 (Mycolicibacteriumsmegmatis) |
PF01261(AP_endonuc_2) | 5 | LEU A 109LEU A 106ILE A 66SER A 88THR A 86 | None | 1.14A | 4f4dB-5tnvA:undetectable | 4f4dB-5tnvA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr9 | FERREDOXIN-NADPREDUCTASE (Neisseriagonorrhoeae) |
PF00175(NAD_binding_1) | 5 | LEU A 136LEU A 139ILE A 132SER A 184THR A 150 | None | 0.85A | 4f4dB-5tr9A:3.7 | 4f4dB-5tr9A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v6b | PDZDOMAIN-CONTAININGPROTEIN GIPC1 (Mus musculus) |
PF00595(PDZ) | 5 | LEU A 145LEU A 198LEU A 201ILE A 157VAL A 134 | None | 0.93A | 4f4dB-5v6bA:undetectable | 4f4dB-5v6bA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdu | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
no annotation | 5 | LEU G 285LEU G 260SER G 256THR G 257VAL G 101 | None | 1.06A | 4f4dB-5wduG:undetectable | 4f4dB-5wduG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wml | - (-) |
no annotation | 5 | LEU A 379LEU A 375ILE A 398SER A 451VAL A 430 | None | 1.25A | 4f4dB-5wmlA:2.7 | 4f4dB-5wmlA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z24 | PILUS ASSEMBLYPROTEIN (Lactobacillusrhamnosus) |
no annotation | 5 | LEU A 436LEU A 431ILE A 409THR A 378VAL A 397 | None | 1.18A | 4f4dB-5z24A:undetectable | 4f4dB-5z24A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6an0 | HISTIDINOLDEHYDROGENASE (Elizabethkingiaanophelis) |
PF00815(Histidinol_dh) | 5 | LEU A 236ARG A 302ILE A 304SER A 340THR A 339 | None | 1.12A | 4f4dB-6an0A:3.1 | 4f4dB-6an0A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6beg | SCAFFOLD PROTEIN D13 (Vaccinia virus) |
no annotation | 5 | LEU A 452LEU A 443ILE A 492THR A 474VAL A 246 | None | 1.13A | 4f4dB-6begA:undetectable | 4f4dB-6begA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d21 | FERM, RHOGEF ANDPLECKSTRIN DOMAINPROTEIN 2 (Danio rerio) |
no annotation | 5 | LEU A 197LEU A 155LEU A 160LYS A 206ILE A 207 | None | 1.23A | 4f4dB-6d21A:undetectable | 4f4dB-6d21A:undetectable |