SIMILAR PATTERNS OF AMINO ACIDS FOR 4F4D_A_CHDA505_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eiz FTSJ

(Escherichia
coli) 		PF01728
(FtsJ) 		4 MET A 150
ILE A  80
ARG A  78
ARG A 112
 None
 1.34A 4f4dA-1eizA:
2.2		 4f4dA-1eizA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgg GLUCURONYLTRANSFERAS
E I

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 MET A 253
ARG A 169
VAL A 213
MET A 207
 None
 1.29A 4f4dA-1fggA:
2.7		 4f4dA-1fggA:
19.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae) 		PF00762
(Ferrochelatase) 		4 ILE A  83
ARG A  87
VAL A 277
TRP A 282
 None
 0.60A 4f4dA-1lbqA:
48.4		 4f4dA-1lbqA:
49.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5d CARBONYL
REDUCTASE/20BETA-HYD
ROXYSTEROID
DEHYDROGENASE

(Sus scrofa) 		PF00106
(adh_short) 		4 ILE A 162
ARG A 209
VAL A 200
MET A 115
 None
 1.40A 4f4dA-1n5dA:
2.2		 4f4dA-1n5dA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1quq PROTEIN (REPLICATION
PROTEIN A 14 KD
SUBUNIT)

(Homo sapiens) 		PF08661
(Rep_fac-A_3) 		4 MET B  16
ILE B 106
ARG B  11
VAL B  28
 None
 1.42A 4f4dA-1quqB:
undetectable		 4f4dA-1quqB:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uio ADENOSINE DEAMINASE

(Mus musculus) 		PF00962
(A_deaminase) 		4 ILE A  79
ARG A  76
VAL A 112
TRP A 161
 None
 1.20A 4f4dA-1uioA:
undetectable		 4f4dA-1uioA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v84 GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 1

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 MET A 255
ARG A 178
VAL A 214
MET A 208
 None
 1.34A 4f4dA-1v84A:
0.0		 4f4dA-1v84A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vz8 ORNITHINE
ACETYL-TRANSFERASE

(Streptomyces
clavuligerus) 		PF01960
(ArgJ) 		4 ILE A 146
ARG A  26
VAL A 172
MET A 174
 None
None
None
SO4  A1391 ( 4.0A)
 1.29A 4f4dA-1vz8A:
undetectable		 4f4dA-1vz8A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkk NUCLEOSIDE
DIPHOSPHATE KINASE

(Thermus
thermophilus) 		PF00334
(NDK) 		4 MET A  73
ILE A 114
ARG A 102
VAL A  80
 None
None
GDP  A1001 ( 4.7A)
None
 1.36A 4f4dA-1wkkA:
undetectable		 4f4dA-1wkkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zs6 NUCLEOSIDE
DIPHOSPHATE KINASE 3

(Homo sapiens) 		PF00334
(NDK) 		4 MET A  93
ILE A 134
ARG A 122
VAL A 100
 None
None
ADP  A 201 (-3.5A)
None
 1.38A 4f4dA-1zs6A:
undetectable		 4f4dA-1zs6A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0j GALACTOSYLGALACTOSYL
XYLOSYLPROTEIN
3-BETA-GLUCURONOSYLT
RANSFERASE 2

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 MET A 244
ARG A 168
VAL A 204
MET A 198
 None
 1.33A 4f4dA-2d0jA:
undetectable		 4f4dA-2d0jA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gz3 ASPARTATE
BETA-SEMIALDEHYDE
DEHYDROGENASE

(Streptococcus
pneumoniae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 MET A 134
ILE A 237
VAL A 151
MET A 319
 None
 1.22A 4f4dA-2gz3A:
4.1		 4f4dA-2gz3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mzw ELONGATION FACTOR G

(Staphylococcus
aureus) 		PF00679
(EFG_C)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		4 ILE A 682
ARG A 627
VAL A 646
MET A 670
 None
 1.45A 4f4dA-2mzwA:
undetectable		 4f4dA-2mzwA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlz CEPHALOSPORIN
ACYLASE

(Bacillus
halodurans) 		PF01019
(G_glu_transpept) 		4 ILE A 456
ARG A 260
VAL A 283
MET A 304
 None
 1.35A 4f4dA-2nlzA:
undetectable		 4f4dA-2nlzA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi2 REPLICATION PROTEIN
A 14 KDA SUBUNIT

(Homo sapiens) 		PF08661
(Rep_fac-A_3) 		4 MET E  16
ILE E 106
ARG E  11
VAL E  28
 None
 1.44A 4f4dA-2pi2E:
undetectable		 4f4dA-2pi2E:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjp CYTOCHROME B
CYTOCHROME C1

(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B)
PF02167
(Cytochrom_C1) 		4 ILE A 424
ARG A 230
ARG A  39
VAL B 255
 None
 1.42A 4f4dA-2qjpA:
undetectable		 4f4dA-2qjpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qn0 NEUROTOXIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 MET A 199
ILE A 387
ARG A  96
VAL A 369
 None
 1.28A 4f4dA-2qn0A:
undetectable		 4f4dA-2qn0A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzp ACYLAMINO-ACID-RELEA
SING ENZYME

(Aeropyrum
pernix) 		PF00326
(Peptidase_S9) 		4 MET A 450
ILE A 411
ARG A 398
VAL A 346
 None
 1.44A 4f4dA-2qzpA:
2.6		 4f4dA-2qzpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9v ATP SYNTHASE SUBUNIT
ALPHA

(Thermotoga
maritima) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 MET A 465
ILE A 494
VAL A 435
MET A 429
 None
 1.35A 4f4dA-2r9vA:
undetectable		 4f4dA-2r9vA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rae TRANSCRIPTIONAL
REGULATOR, ACRR
FAMILY PROTEIN

(Rhodococcus
jostii) 		PF00440
(TetR_N) 		4 MET A 131
ILE A 118
ARG A 114
MET A  76
 None
 1.36A 4f4dA-2raeA:
undetectable		 4f4dA-2raeA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4i GLUTAMATE
N-ACETYLTRANSFERASE
2 ALPHA CHAIN

(Streptomyces
clavuligerus) 		PF01960
(ArgJ) 		4 ILE A 146
ARG A  26
VAL A 172
MET A 174
 None
 1.17A 4f4dA-2v4iA:
undetectable		 4f4dA-2v4iA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yru STEROID RECEPTOR RNA
ACTIVATOR 1

(Mus musculus) 		PF07304
(SRA1) 		4 MET A  99
ILE A 106
VAL A  18
TRP A  52
 None
 1.45A 4f4dA-2yruA:
undetectable		 4f4dA-2yruA:
14.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		5 MET A  99
ILE A 111
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.32A 4f4dA-3aqiA:
60.3		 4f4dA-3aqiA:
99.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be5 PUTATIVE IRON
COMPOUND-BINDING
PROTEIN OF ABC
TRANSPORTER FAMILY

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		4 MET A 196
ILE A 288
ARG A  76
ARG A 284
 None
 1.48A 4f4dA-3be5A:
undetectable		 4f4dA-3be5A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 ILE A 476
ARG A 356
VAL A 501
TRP A 497
 None
 1.46A 4f4dA-3bgaA:
undetectable		 4f4dA-3bgaA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhu PREPILIN

(Salmonella
enterica) 		PF08805
(PilS) 		4 MET A  77
ILE A 116
VAL A 121
TRP A  94
 None
 1.50A 4f4dA-3fhuA:
undetectable		 4f4dA-3fhuA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Schizosaccharomyces
pombe) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 MET A 495
ILE A 442
ARG A 440
MET A 512
 None
 1.50A 4f4dA-3h0gA:
undetectable		 4f4dA-3h0gA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln3 DIHYDRODIOL
DEHYDROGENASE

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 MET A 116
ARG A 171
VAL A 142
MET A 122
 None
SO4  A 324 (-3.9A)
None
None
 1.31A 4f4dA-3ln3A:
undetectable		 4f4dA-3ln3A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ome ENOYL-COA HYDRATASE

(Mycolicibacterium
smegmatis) 		PF00378
(ECH_1) 		4 ILE A  50
ARG A 192
ARG A  52
MET A   0
 None
 1.22A 4f4dA-3omeA:
undetectable		 4f4dA-3omeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pie 5'->3'
EXORIBONUCLEASE
(XRN1)

(Kluyveromyces
lactis) 		PF03159
(XRN_N) 		4 ILE A 264
ARG A 375
MET A 767
TRP A  14
 None
 1.20A 4f4dA-3pieA:
undetectable		 4f4dA-3pieA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v76 FLAVOPROTEIN

(Sinorhizobium
meliloti) 		PF03486
(HI0933_like) 		4 MET A  19
ARG A  27
VAL A 417
MET A 355
 None
 1.37A 4f4dA-3v76A:
undetectable		 4f4dA-3v76A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsk PENICILLIN-BINDING
PROTEIN 3

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 ILE A  72
ARG A 230
ARG A  71
VAL A 564
 None
 1.33A 4f4dA-3vskA:
undetectable		 4f4dA-3vskA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b90 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 ILE A  98
ARG A 189
VAL A 351
MET A 355
 None
 1.00A 4f4dA-4b90A:
undetectable		 4f4dA-4b90A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b92 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 ILE A  98
ARG A 189
VAL A 351
MET A 355
 None
 1.01A 4f4dA-4b92A:
undetectable		 4f4dA-4b92A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 MET A 124
ILE A  11
VAL A  77
TRP A  80
 None
 1.24A 4f4dA-4cbwA:
undetectable		 4f4dA-4cbwA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnx PUTATIVE
UNCHARACTERIZED
PROTEIN

(Ustilago maydis) 		PF01336
(tRNA_anti-codon)
PF08646
(Rep_fac-A_C)
PF16900
(REPA_OB_2) 		4 ILE C 303
ARG C 302
VAL C 385
MET C 395
 None
 1.43A 4f4dA-4gnxC:
undetectable		 4f4dA-4gnxC:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT

(Escherichia
coli;
Mus musculus) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 ILE A1220
ARG A1216
ARG A1219
TRP A1151
 None
 1.49A 4f4dA-4nufA:
undetectable		 4f4dA-4nufA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl7 ACTIN,THYMOSIN
BETA-4

(Homo sapiens;
Komagataella
phaffii) 		PF00022
(Actin)
PF01290
(Thymosin) 		4 MET A 123
ILE A  10
VAL A  76
TRP A  79
 None
 1.20A 4f4dA-4pl7A:
undetectable		 4f4dA-4pl7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q0c VIRULENCE SENSOR
PROTEIN BVGS

(Bordetella
pertussis) 		PF00497
(SBP_bac_3) 		4 ARG A 234
ARG A 160
VAL A 308
MET A 303
 None
 1.47A 4f4dA-4q0cA:
undetectable		 4f4dA-4q0cA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkm MCCA

(Wolinella
succinogenes) 		no annotation 4 MET A 492
ILE A 517
VAL A 530
TRP A 544
 None
 1.08A 4f4dA-4rkmA:
undetectable		 4f4dA-4rkmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv6 2-DEHYDRO-3-DEOXYGLU
CARATE ALDOLASE

(Staphylococcus
aureus) 		PF03328
(HpcH_HpaI) 		4 MET A  29
ILE A 241
ARG A 238
VAL A  48
 None
 1.36A 4f4dA-4tv6A:
undetectable		 4f4dA-4tv6A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v10 MYOMESIN-1

(Mus musculus) 		PF07679
(I-set) 		4 ILE A 162
ARG A 213
VAL A 169
TRP A 170
 None
 1.29A 4f4dA-4v10A:
undetectable		 4f4dA-4v10A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cni METABOTROPIC
GLUTAMATE RECEPTOR 2

(Homo sapiens) 		PF01094
(ANF_receptor) 		4 MET A 195
ILE A 221
VAL A 265
TRP A 204
 None
 1.29A 4f4dA-5cniA:
6.4		 4f4dA-5cniA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e44 FNR REGULATOR

(Aliivibrio
fischeri) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ILE A 200
ARG A 197
VAL A 226
MET A 223
 None
 1.08A 4f4dA-5e44A:
undetectable		 4f4dA-5e44A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eks 3-DEHYDROQUINATE
SYNTHASE

(Acinetobacter
baumannii) 		PF01761
(DHQ_synthase) 		4 ILE A 228
ARG A 227
VAL A 331
MET A 271
 None
 1.30A 4f4dA-5eksA:
undetectable		 4f4dA-5eksA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipf HYPOXANTHINE-GUANINE
PHOSPHORIBOSYLTRANSF
ERASE (HGPRT)

(Schistosoma
mansoni) 		PF00156
(Pribosyltran) 		4 MET A  44
ILE A  13
ARG A 173
MET A  52
 None
 1.48A 4f4dA-5ipfA:
3.1		 4f4dA-5ipfA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6o PUTATIVE POLYKETIDE
SYNTHASE

(Brevibacillus
brevis) 		PF14765
(PS-DH) 		4 MET A2132
ILE A2171
VAL A2000
TRP A2002
 None
 1.12A 4f4dA-5j6oA:
undetectable		 4f4dA-5j6oA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzn METABOTROPIC
GLUTAMATE RECEPTOR 2

(Homo sapiens) 		PF01094
(ANF_receptor)
PF07562
(NCD3G) 		4 MET A 195
ILE A 221
VAL A 265
TRP A 204
 None
 1.43A 4f4dA-5kznA:
3.2		 4f4dA-5kznA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogl UNDECAPRENYL-DIPHOSP
HOOLIGOSACCHARIDE--P
ROTEIN
GLYCOTRANSFERASE

(Campylobacter
lari) 		no annotation 4 MET A 318
ILE A 572
ARG A 568
VAL A 438
 None
 1.46A 4f4dA-5oglA:
undetectable		 4f4dA-5oglA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z0u NEOPULLULANASE 1

(Thermoactinomyces
vulgaris) 		no annotation 4 ILE A 473
ARG A 479
ARG A 475
MET A 135
 None
 1.28A 4f4dA-5z0uA:
undetectable		 4f4dA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ehs HYDROGENASE-2 LARGE
CHAIN

(Escherichia
coli) 		no annotation 4 ILE L  91
ARG L  92
VAL L  73
MET L  55
 None
 1.39A 4f4dA-6ehsL:
undetectable		 4f4dA-6ehsL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eq8 PERIPLASMIC
ALPHA-GALACTOSIDE-BI
NDING PROTEIN

(Agrobacterium
tumefaciens) 		no annotation 4 ILE D  34
ARG D 648
ARG D 123
MET D 636
 None
 1.42A 4f4dA-6eq8D:
undetectable		 4f4dA-6eq8D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1

(Sus scrofa) 		no annotation 4 ILE E  13
ARG E  14
VAL E  60
MET E  72
 None
 1.43A 4f4dA-6exvE:
undetectable		 4f4dA-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens) 		no annotation 4 ILE A1751
ARG A 780
VAL A1662
MET A1659
 None
 1.32A 4f4dA-6ez8A:
undetectable		 4f4dA-6ez8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 4 ILE B 127
ARG B 128
VAL B  78
TRP B  77
 None
 1.32A 4f4dA-6fosB:
undetectable		 4f4dA-6fosB:
undetectable