SIMILAR PATTERNS OF AMINO ACIDS FOR 4EVY_A_TOYA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s5k AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE

(Salmonella
enterica) 		PF00583
(Acetyltransf_1) 		5 ARG A  18
TRP A  22
GLU A  79
GLY A  80
ASP A 115
 None
None
None
COA  A 600 ( 3.8A)
None
 0.64A 4evyA-1s5kA:
23.3
4evyB-1s5kA:
22.8		 4evyA-1s5kA:
43.79
4evyB-1s5kA:
43.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4e8o AAC(6')-IH PROTEIN

(Acinetobacter
baumannii) 		PF00583
(Acetyltransf_1) 		6 ARG A  18
TRP A  22
GLU A  32
GLU A  79
GLY A  80
ASP A 115
 None
None
None
None
None
CL  A 201 ( 3.9A)
 0.37A 4evyA-4e8oA:
25.8
4evyB-4e8oA:
24.6		 4evyA-4e8oA:
74.25
4evyB-4e8oA:
74.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f0y AMINOGLYCOSIDE
N(6')-ACETYLTRANSFER
ASE TYPE 1

(Acinetobacter
haemolyticus) 		PF00583
(Acetyltransf_1) 		6 ARG A  18
TRP A  22
GLU A  32
GLU A  78
GLY A  79
ASP A 114
 GOL  A 203 ( 4.4A)
GOL  A 203 (-3.4A)
GOL  A 203 (-3.9A)
GOL  A 203 (-3.8A)
None
MG  A 201 (-3.1A)
 0.63A 4evyA-4f0yA:
26.4
4evyB-4f0yA:
25.3		 4evyA-4f0yA:
100.00
4evyB-4f0yA:
100.00