SIMILAR PATTERNS OF AMINO ACIDS FOR 4EQL_B_SALB602
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bkh | MUCONATE LACTONIZINGENZYME (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 360ILE A 352THR A 355GLY A 357 | None | 0.95A | 4eqlB-1bkhA:1.1 | 4eqlB-1bkhA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3x | PENTOSYLTRANSFERASE (Cellulomonassp.) |
PF01048(PNP_UDP_1) | 4 | LEU A 98THR A 82ILE A 67GLY A 118 | None | 0.91A | 4eqlB-1c3xA:undetectable | 4eqlB-1c3xA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | THR A 139ILE A 106THR A 430GLY A 432 | None | 0.93A | 4eqlB-1d2eA:1.4 | 4eqlB-1d2eA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnn | CELL DIVISIONCONTROL PROTEIN 6 (Pyrobaculumaerophilum) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | LEU A 274THR A 226ILE A 222GLY A 368 | None | 0.91A | 4eqlB-1fnnA:undetectable | 4eqlB-1fnnA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyh | L-2-HYDROXYISOCAPROATE DEHYDROGENASE (Weissellaconfusa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | THR A 166ILE A 141THR A 248GLY A 251 | NAD A 330 (-4.7A)NAD A 330 (-4.7A)SO4 A 331 ( 3.0A)None | 0.89A | 4eqlB-1hyhA:1.4 | 4eqlB-1hyhA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsd | HAEMAGGLUTININ (HA1CHAIN) (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 184TYR A 185ILE A 242GLY A 128 | None | 0.88A | 4eqlB-1jsdA:undetectable | 4eqlB-1jsdA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jxi | PHOSPHOMETHYLPYRIMIDINE KINASE (Salmonellaenterica) |
PF08543(Phos_pyr_kin) | 4 | THR A 12ILE A 38THR A 8GLY A 79 | None | 0.95A | 4eqlB-1jxiA:0.9 | 4eqlB-1jxiA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m72 | CASPASE-1 (Spodopterafrugiperda) |
PF00656(Peptidase_C14) | 4 | LEU A 166THR A 118ILE A 64GLY A 61 | None | 0.91A | 4eqlB-1m72A:1.8 | 4eqlB-1m72A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oi1 | SCML2 PROTEIN (Homo sapiens) |
PF02820(MBT) | 4 | LEU A 109ILE A 189THR A 233GLY A 90 | None | 0.95A | 4eqlB-1oi1A:undetectable | 4eqlB-1oi1A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pw5 | NAGD PROTEIN,PUTATIVE (Thermotogamaritima) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | LEU A 92THR A 95THR A 146GLY A 74 | None | 0.94A | 4eqlB-1pw5A:undetectable | 4eqlB-1pw5A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | APOCYTOCHROME F (Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 4 | LEU A 100TYR A 102ILE A 49GLY A 72 | NoneNoneNoneHEM A 900 (-3.9A) | 0.93A | 4eqlB-1q90A:undetectable | 4eqlB-1q90A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ti8 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.91A | 4eqlB-1ti8A:undetectable | 4eqlB-1ti8A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v76 | RNASE P PROTEINPH1771P (Pyrococcushorikoshii) |
PF01868(UPF0086) | 4 | LEU A 78ARG A 119ILE A 43GLY A 109 | None | 0.96A | 4eqlB-1v76A:undetectable | 4eqlB-1v76A:9.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xaj | 3-DEHYDROQUINATESYNTHASE (Staphylococcusaureus) |
PF01761(DHQ_synthase) | 4 | LEU A 184TYR A 180ILE A 265GLY A 241 | None | 0.91A | 4eqlB-1xajA:undetectable | 4eqlB-1xajA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfd | DIPEPTIDYLAMINOPEPTIDASE-LIKEPROTEIN 6 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | THR A 800ILE A 786THR A 719GLY A 715 | None | 0.93A | 4eqlB-1xfdA:undetectable | 4eqlB-1xfdA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3d | MODULATOR OF DRUGACTIVITY B (Escherichiacoli) |
PF02525(Flavodoxin_2) | 4 | LEU A 199TYR A 195ILE A 17GLY A 41 | None | 0.83A | 4eqlB-2b3dA:undetectable | 4eqlB-2b3dA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g02 | NISIN BIOSYNTHESISPROTEIN NISC (Lactococcuslactis) |
PF05147(LANC_like) | 4 | LEU A 39TYR A 88ILE A 329GLY A 377 | None | 0.76A | 4eqlB-2g02A:undetectable | 4eqlB-2g02A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hf8 | PROBABLE HYDROGENASENICKEL INCORPORATIONPROTEIN HYPB (Methanocaldococcusjannaschii) |
PF02492(cobW) | 4 | LEU A 28THR A 135ILE A 119GLY A 103 | None | 0.74A | 4eqlB-2hf8A:1.6 | 4eqlB-2hf8A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0k | POLYCOMB PROTEINSCMH1 (Homo sapiens) |
PF02820(MBT) | 4 | LEU A 104ILE A 184THR A 228GLY A 85 | None | 0.85A | 4eqlB-2p0kA:undetectable | 4eqlB-2p0kA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4y | URIDYLATE KINASE (Escherichiacoli) |
PF00696(AA_kinase) | 4 | LEU A 197THR A 172THR A 237GLY A 169 | None | 0.91A | 4eqlB-2v4yA:undetectable | 4eqlB-2v4yA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsk | HEMAGGLUTININ-NEURAMINIDASE (Hendrahenipavirus) |
PF00423(HN) | 4 | LEU A 198TYR A 547ILE A 514GLY A 523 | None | 0.95A | 4eqlB-2vskA:undetectable | 4eqlB-2vskA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrd | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 193TYR A 194ILE A 251GLY A 133 | None | 0.82A | 4eqlB-2wrdA:undetectable | 4eqlB-2wrdA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y89 | PHOSPHORIBOSYLISOMERASE A (Mycobacteriumtuberculosis) |
PF00977(His_biosynth) | 4 | LEU A 185THR A 170ILE A 172GLY A 176 | None | 0.95A | 4eqlB-2y89A:undetectable | 4eqlB-2y89A:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp2 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.83A | 4eqlB-2yp2A:undetectable | 4eqlB-2yp2A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zae | RIBONUCLEASE PPROTEIN COMPONENT 1 (Pyrococcushorikoshii) |
PF01868(UPF0086) | 4 | LEU A 78ARG A 119ILE A 43GLY A 109 | None | 0.95A | 4eqlB-2zaeA:undetectable | 4eqlB-2zaeA:11.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afg | SUBTILISIN-LIKESERINE PROTEASE (Thermococcuskodakarensis) |
PF00082(Peptidase_S8)PF04151(PPC) | 4 | ARG A 322THR A 299THR A 318GLY A 316 | None | 0.96A | 4eqlB-3afgA:undetectable | 4eqlB-3afgA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TYR A 447THR A 438ILE A 432GLY A 416 | None | 0.95A | 4eqlB-3ai7A:undetectable | 4eqlB-3ai7A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bga | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 898ARG A 901THR A 927GLY A 554 | None | 0.90A | 4eqlB-3bgaA:undetectable | 4eqlB-3bgaA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cr3 | PTS-DEPENDENTDIHYDROXYACETONEKINASE, ADP-BINDINGSUBUNIT DHALPTS-DEPENDENTDIHYDROXYACETONEKINASE,PHOSPHOTRANSFERASESUBUNIT DHAM (Lactococcuslactis) |
PF02734(Dak2)PF03610(EIIA-man) | 4 | LEU C 67ILE C 42THR C 44GLY A 77 | NoneNoneNoneADP A1211 (-3.3A) | 0.92A | 4eqlB-3cr3C:undetectable | 4eqlB-3cr3C:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6k | PUTATIVEAMINOTRANSFERASE (Corynebacteriumdiphtheriae) |
PF12897(Aminotran_MocR) | 4 | LEU A 50ILE A 78THR A 253GLY A 262 | None | 0.90A | 4eqlB-3d6kA:undetectable | 4eqlB-3d6kA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dea | CUTINASE (Colletotrichumgloeosporioides) |
PF01083(Cutinase) | 4 | THR A 183ILE A 175THR A 139GLY A 133 | None | 0.92A | 4eqlB-3deaA:undetectable | 4eqlB-3deaA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dec | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 874ARG A 877THR A 903GLY A 530 | None | 0.95A | 4eqlB-3decA:2.2 | 4eqlB-3decA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eof | PUTATIVEOXIDOREDUCTASE (Bacteroidesfragilis) |
PF00881(Nitroreductase) | 4 | THR A 75ILE A 140THR A 134GLY A 131 | NoneNoneNoneFMN A 300 (-3.5A) | 0.70A | 4eqlB-3eofA:undetectable | 4eqlB-3eofA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f72 | CADMIUM EFFLUXSYSTEM ACCESSORYPROTEIN (Staphylococcusaureus) |
PF01022(HTH_5) | 4 | LEU A 99THR A 48ILE A 39GLY A 84 | None | 0.89A | 4eqlB-3f72A:undetectable | 4eqlB-3f72A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gde | DNA LIGASE (Archaeoglobusfulgidus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | LEU A 70TYR A 144ILE A 159GLY A 64 | None | 0.86A | 4eqlB-3gdeA:undetectable | 4eqlB-3gdeA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivr | PUTATIVELONG-CHAIN-FATTY-ACID COA LIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding) | 4 | LEU A 353THR A 357THR A 313GLY A 304 | None | 0.96A | 4eqlB-3ivrA:7.2 | 4eqlB-3ivrA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9d | OUTER CAPSID PROTEINVP2 (Bluetonguevirus) |
PF00898(Orbi_VP2) | 4 | LEU A 604TYR A 600THR A 621GLY A 161 | None | 0.94A | 4eqlB-3j9dA:2.6 | 4eqlB-3j9dA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jd8 | NIEMANN-PICK C1PROTEIN (Homo sapiens) |
PF02460(Patched)PF12349(Sterol-sensing)PF16414(NPC1_N) | 4 | LEU A1191THR A1172ILE A1126GLY A1240 | None | 0.93A | 4eqlB-3jd8A:undetectable | 4eqlB-3jd8A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juu | PORPHYRANASE B (Zobelliagalactanivorans) |
PF00722(Glyco_hydro_16) | 4 | ARG A 187ILE A 141THR A 154GLY A 144 | SO4 A 7 (-3.9A)MES A 1 (-4.0A)SO4 A 7 ( 4.2A)None | 0.94A | 4eqlB-3juuA:undetectable | 4eqlB-3juuA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhi | PUTATIVE6-PHOSPHOGLUCONOLACTONASE (Neisseriagonorrhoeae) |
PF01182(Glucosamine_iso) | 4 | LEU A 218ILE A 192THR A 140GLY A 138 | None | 0.95A | 4eqlB-3lhiA:undetectable | 4eqlB-3lhiA:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | LEU A 321THR A 229ILE A 329GLY A 326 | None | 0.81A | 4eqlB-3lpdA:undetectable | 4eqlB-3lpdA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwd | 6-PHOSPHOGLUCONOLACTONASE (Chromohalobactersalexigens) |
PF01182(Glucosamine_iso) | 4 | LEU A 215ILE A 188THR A 138GLY A 136 | None | 0.85A | 4eqlB-3lwdA:undetectable | 4eqlB-3lwdA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwf | PUTATIVETRANSCRIPTIONALREGULATOR (Listeriainnocua) |
PF02082(Rrf2) | 4 | LEU A 67THR A 14ILE A 79GLY A 53 | None | 0.96A | 4eqlB-3lwfA:undetectable | 4eqlB-3lwfA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o59 | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcushorikoshii) |
PF03833(PolC_DP2) | 4 | LEU X 250TYR X 194THR X 226GLY X 148 | None | 0.87A | 4eqlB-3o59X:2.3 | 4eqlB-3o59X:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4d | POSSIBLECHLOROMUCONATECYCLOISOMERASEMANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY (Cytophagahutchinsonii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 323ILE A 334THR A 132GLY A 340 | None | 0.91A | 4eqlB-3q4dA:undetectable | 4eqlB-3q4dA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqi | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | NoneNoneNoneEPE A3380 (-3.4A) | 0.78A | 4eqlB-3qqiA:undetectable | 4eqlB-3qqiA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 4 | LEU M 211TYR M 207ILE M 496GLY M 59 | None | 0.90A | 4eqlB-3rkoM:undetectable | 4eqlB-3rkoM:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti7 | BASIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE BPRV (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | LEU A 321THR A 229ILE A 329GLY A 326 | None | 0.80A | 4eqlB-3ti7A:undetectable | 4eqlB-3ti7A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4g | NAMN:DMBPHOSPHORIBOSYLTRANSFERASE (Pyrococcushorikoshii) |
no annotation | 4 | LEU A 125ILE A 138THR A 210GLY A 213 | None | 0.96A | 4eqlB-3u4gA:1.4 | 4eqlB-3u4gA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyy | IRON-SULFUR CLUSTERBINDING PROTEIN (Carboxydothermushydrogenoformans) |
PF00111(Fer2)PF14574(DUF4445) | 4 | LEU X 116THR X 364ILE X 539GLY X 571 | None | 0.92A | 4eqlB-3zyyX:undetectable | 4eqlB-3zyyX:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2b | CELL DIVISIONPROTEIN FTSA,PUTATIVE (Thermotogamaritima) |
PF02491(SHS2_FTSA)PF14450(FtsA) | 4 | LEU A 64ILE A 81THR A 11GLY A 22 | None | 0.72A | 4eqlB-4a2bA:undetectable | 4eqlB-4a2bA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | THR B1760ILE B1824THR B1818GLY B1814 | None | 0.93A | 4eqlB-4bedB:undetectable | 4eqlB-4bedB:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci8 | ECHINODERMMICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 (Homo sapiens) |
PF00400(WD40)PF03451(HELP) | 4 | THR A 560ILE A 809THR A 807GLY A 804 | None | 0.93A | 4eqlB-4ci8A:undetectable | 4eqlB-4ci8A:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hfu | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.89A | 4eqlB-4hfuA:undetectable | 4eqlB-4hfuA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkx | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU E 194TYR E 195ILE E 252GLY E 134 | None | 0.83A | 4eqlB-4hkxE:undetectable | 4eqlB-4hkxE:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0q | ELONGATION FACTORTU-A (Pseudomonasputida) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | THR A 94ILE A 61THR A 386GLY A 388 | None | 0.94A | 4eqlB-4j0qA:undetectable | 4eqlB-4j0qA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhi | MTN13 PROTEIN (Medicagotruncatula) |
PF00407(Bet_v_1) | 4 | LEU A 90TYR A 133ILE A 98GLY A 87 | NoneEMU A 202 ( 4.3A)EMU A 202 ( 4.9A)None | 0.93A | 4eqlB-4jhiA:undetectable | 4eqlB-4jhiA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqb | PROTEIN H03A11.1 (Caenorhabditiselegans) |
PF06702(Fam20C) | 4 | LEU A 358ARG A 367THR A 221GLY A 363 | None | 0.96A | 4eqlB-4kqbA:undetectable | 4eqlB-4kqbA:21.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4l39 | 4-SUBSTITUTEDBENZOATES-GLUTAMATELIGASE GH3.12 (Arabidopsisthaliana) |
PF03321(GH3) | 7 | LEU A 116TYR A 120ARG A 123THR A 161ILE A 217THR A 324GLY A 326 | SAL A 602 (-4.7A)SAL A 602 (-4.3A)SAL A 602 (-3.1A)NoneSAL A 602 ( 4.4A)SAL A 602 ( 3.7A)SAL A 602 ( 3.6A) | 0.26A | 4eqlB-4l39A:54.9 | 4eqlB-4l39A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mae | METHANOLDEHYDROGENASE (Methylacidiphilumfumariolicum) |
PF13360(PQQ_2) | 4 | ARG A 265THR A 370THR A 259GLY A 427 | None | 0.69A | 4eqlB-4maeA:undetectable | 4eqlB-4maeA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb7 | ENDONUCLEASE 8-LIKEL720 (Acanthamoebapolyphagamimivirus) |
PF06831(H2TH) | 4 | TYR A 103THR A 85ILE A 91GLY A 79 | None | 0.66A | 4eqlB-4mb7A:undetectable | 4eqlB-4mb7A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mca | GLYCEROLDEHYDROGENASE (Serratiaplymuthica) |
PF00465(Fe-ADH) | 4 | LEU A 211TYR A 207ARG A 204THR A 295 | None | 0.95A | 4eqlB-4mcaA:undetectable | 4eqlB-4mcaA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mea | PREDICTED PROTEIN (Acinetobacternosocomialis) |
PF00561(Abhydrolase_1) | 4 | LEU A 167TYR A 154ILE A 114GLY A 141 | None | 0.85A | 4eqlB-4meaA:undetectable | 4eqlB-4meaA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o87 | N-TAGGED NUCLEASE (Millerozymaacaciae) |
no annotation | 4 | LEU A 200ILE A 268THR A 183GLY A 180 | None | 0.80A | 4eqlB-4o87A:undetectable | 4eqlB-4o87A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovm | UNCHARACTERIZEDPROTEIN SGCJ (Streptomycescarzinostaticus) |
PF14534(DUF4440) | 4 | TYR A 136ILE A 118THR A 100GLY A 83 | None | 0.76A | 4eqlB-4ovmA:undetectable | 4eqlB-4ovmA:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4we6 | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 154TYR A 155ILE A 212GLY A 94 | NoneNoneNoneGOL A 303 (-3.4A) | 0.86A | 4eqlB-4we6A:undetectable | 4eqlB-4we6A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | LEU A 60THR A 405ILE A 554GLY A 40 | None | 0.90A | 4eqlB-4y23A:undetectable | 4eqlB-4y23A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zcf | RESTRICTIONENDONUCLEASEECOP15I, RESTRICTIONSUBUNIT (Escherichiacoli) |
PF04851(ResIII) | 4 | LEU C 267TYR C 265THR C 93GLY C 89 | NoneNoneNoneAMP C1001 (-3.4A) | 0.95A | 4eqlB-4zcfC:undetectable | 4eqlB-4zcfC:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zch | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B (Homo sapiens) |
PF00229(TNF) | 4 | LEU A 420THR A 436ILE A 429GLY A 368 | None | 0.96A | 4eqlB-4zchA:undetectable | 4eqlB-4zchA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 4 | LEU A 287THR A 21ILE A 10THR A 99 | None | 0.90A | 4eqlB-4zqgA:undetectable | 4eqlB-4zqgA:24.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 4 | LEU A2014ILE A2022THR A2020GLY A2130 | None | 0.83A | 4eqlB-5b4xA:undetectable | 4eqlB-5b4xA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9e | SEPL (Escherichiacoli) |
PF07201(HrpJ) | 4 | LEU A 167ILE A 100THR A 95GLY A 172 | None | 0.75A | 4eqlB-5c9eA:undetectable | 4eqlB-5c9eA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dm3 | L-GLUTAMINESYNTHETASE (Chromohalobactersalexigens) |
PF00120(Gln-synt_C) | 4 | ARG A 190THR A 179THR A 203GLY A 205 | None | 0.83A | 4eqlB-5dm3A:undetectable | 4eqlB-5dm3A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbz | ENZYME SUBTILASESUBHAL FROM BACILLUSHALMAPALUS (Bacillushalmapalus) |
PF00082(Peptidase_S8)PF04151(PPC) | 4 | ARG A 214THR A 180THR A 210GLY A 208 | None | 0.92A | 4eqlB-5fbzA:undetectable | 4eqlB-5fbzA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gne | LEUCINEAMINOPEPTIDASE (Legionellapneumophila) |
PF04389(Peptidase_M28) | 4 | LEU A 287THR A 384ILE A 136GLY A 291 | None | 0.95A | 4eqlB-5gneA:undetectable | 4eqlB-5gneA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 4 | LEU A 391TYR A 382ARG A 389GLY A 248 | None | 0.75A | 4eqlB-5gnmA:undetectable | 4eqlB-5gnmA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hc8 | PRENYLTRANSFERENCEFOR PROTEIN (Lavandulalanata) |
PF01255(Prenyltransf) | 4 | LEU A 135TYR A 139ILE A 75GLY A 92 | 61G A 403 ( 4.5A)NoneNoneNone | 0.90A | 4eqlB-5hc8A:undetectable | 4eqlB-5hc8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | TYR A 23ILE A 812THR A 824GLY A 340 | None | 0.89A | 4eqlB-5i2gA:undetectable | 4eqlB-5i2gA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kan | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.94A | 4eqlB-5kanA:undetectable | 4eqlB-5kanA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | LEU A 198TYR A 116THR A 96GLY A 94 | NoneNoneNoneFAD A 901 ( 4.4A) | 0.85A | 4eqlB-5l46A:undetectable | 4eqlB-5l46A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN3, MITOCHONDRIAL (Bos taurus) |
PF00329(Complex1_30kDa) | 4 | LEU C 61TYR C 94ILE C 117GLY C 56 | None | 0.75A | 4eqlB-5lc5C:undetectable | 4eqlB-5lc5C:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8j | DIVALENT METALCATION TRANSPORTERMNTH (Eremococcuscoleocola) |
PF01566(Nramp) | 4 | ARG A 369THR A 350ILE A 122THR A 372 | None | 0.79A | 4eqlB-5m8jA:undetectable | 4eqlB-5m8jA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me3 | SISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 4 | LEU A 517THR A 513ILE A 433GLY A 428 | None | 0.96A | 4eqlB-5me3A:undetectable | 4eqlB-5me3A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfh | METHIONYL-TRNASYNTHETASE, PUTATIVE (Trypanosomabrucei) |
no annotation | 4 | ARG A 451THR A 398ILE A 365THR A 455 | None | 0.85A | 4eqlB-5nfhA:undetectable | 4eqlB-5nfhA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ELECTRON TRANSFERFLAVOPROTEIN LARGESUBUNITELECTRON TRANSFERFLAVOPROTEIN SMALLSUBUNIT (Clostridioidesdifficile) |
no annotation | 4 | TYR B 147ARG B 162THR A 98ILE A 100 | None | 0.96A | 4eqlB-5ol2B:undetectable | 4eqlB-5ol2B:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tg8 | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.93A | 4eqlB-5tg8A:undetectable | 4eqlB-5tg8A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr7 | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Vibrio cholerae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 4 | LEU A 191TYR A 202ILE A 125GLY A 77 | None | 0.89A | 4eqlB-5tr7A:undetectable | 4eqlB-5tr7A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uao | TRYPTOPHANE-5-HALOGENASE (Microbisporasp. ATCCPTA-5024) |
PF04820(Trp_halogenase) | 4 | THR A 200ILE A 65THR A 232GLY A 36 | FAD A 601 ( 4.6A)FAD A 601 (-3.9A)FAD A 601 (-4.4A)FAD A 601 (-3.4A) | 0.85A | 4eqlB-5uaoA:undetectable | 4eqlB-5uaoA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6t | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.90A | 4eqlB-5w6tA:undetectable | 4eqlB-5w6tA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w75 | ELONGATION FACTOR TU (Thermotoganeapolitana) |
no annotation | 4 | THR A 94ILE A 61THR A 383GLY A 385 | None | 0.88A | 4eqlB-5w75A:1.4 | 4eqlB-5w75A:9.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w76 | ANCESTRAL ELOGATIONFACTOR N153 (syntheticconstruct) |
no annotation | 4 | THR A 94ILE A 61THR A 383GLY A 385 | None | 0.95A | 4eqlB-5w76A:1.4 | 4eqlB-5w76A:7.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xl6 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 191TYR A 192ILE A 249GLY A 130 | SIA A 603 (-4.7A)NoneNoneSIA A 603 ( 4.4A) | 0.95A | 4eqlB-5xl6A:undetectable | 4eqlB-5xl6A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xra | CANNABINOID RECEPTOR1,FLAVODOXIN,CANNABINOID RECEPTOR 1 (Desulfovibriovulgaris;Homo sapiens) |
PF00001(7tm_1)PF00258(Flavodoxin_1) | 4 | LEU A 286THR A 201ILE A 247GLY A 281 | None | 0.75A | 4eqlB-5xraA:undetectable | 4eqlB-5xraA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xrt | - (-) |
no annotation | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.94A | 4eqlB-5xrtA:undetectable | 4eqlB-5xrtA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S21 (Trichomonasvaginalis) |
PF01249(Ribosomal_S21e) | 4 | LEU V 61TYR V 57ARG V 22THR V 20 | U 2 890 ( 4.3A)NoneNoneNone | 0.91A | 4eqlB-5xyiV:undetectable | 4eqlB-5xyiV:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ape | BIFUNCTIONAL PROTEINFOLD (Helicobacterpylori) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | THR A 145ILE A 233THR A 260GLY A 265 | None | 0.96A | 4eqlB-6apeA:undetectable | 4eqlB-6apeA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk5 | UBIQUITIN LIGASE CBL (Salpingoecarosetta) |
no annotation | 4 | LEU A 317THR A 290THR A 298GLY A 287 | None | 0.90A | 4eqlB-6bk5A:undetectable | 4eqlB-6bk5A:9.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bkp | HEMAGGLUTININ (Influenza Avirus) |
no annotation | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.86A | 4eqlB-6bkpA:undetectable | 4eqlB-6bkpA:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d8w | HEMAGGLUTININ (Influenza Avirus) |
no annotation | 4 | LEU A 193TYR A 194ILE A 251GLY A 133 | OXM A 502 (-4.9A)NoneNoneNone | 0.91A | 4eqlB-6d8wA:undetectable | 4eqlB-6d8wA:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f34 | AMINO ACIDTRANSPORTER (Geobacilluskaustophilus) |
no annotation | 4 | LEU A 112TYR A 116ILE A 234GLY A 382 | NoneARG A 501 (-3.9A)ARG A 501 (-3.7A)None | 0.94A | 4eqlB-6f34A:undetectable | 4eqlB-6f34A:9.52 |