SIMILAR PATTERNS OF AMINO ACIDS FOR 4EM2_A_SALA503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae) 		PF00224
(PK)
PF02887
(PK_C) 		4 LYS A  61
ILE A  64
VAL A 207
LEU A  83
 None
 1.01A 4em2A-1a3xA:
0.0		 4em2A-1a3xA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dvk PRP18

(Saccharomyces
cerevisiae) 		PF02840
(Prp18) 		4 LYS A 234
ILE A 237
VAL A 166
LEU A 167
 None
 1.06A 4em2A-1dvkA:
0.0		 4em2A-1dvkA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gxk CHROMOSOME
SEGREGATION SMC
PROTEIN

(Thermotoga
maritima) 		PF06470
(SMC_hinge) 		4 ARG A 548
ILE A 576
VAL A 608
LEU A 609
 None
 0.92A 4em2A-1gxkA:
undetectable		 4em2A-1gxkA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyb NICOTINAMIDE
MONONUCLEOTIDE
ADENYLYLTRANSFERASE

(Methanothermobacter
thermautotrophicus) 		PF01467
(CTP_transf_like) 		4 ARG A 136
ILE A 157
VAL A 153
LEU A 149
 SO4  A1759 (-3.1A)
None
None
None
 1.02A 4em2A-1hybA:
undetectable		 4em2A-1hybA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzv NITRITE REDUCTASE

(Pseudomonas
aeruginosa) 		PF02239
(Cytochrom_D1)
PF13442
(Cytochrome_CBB3) 		4 ARG A 201
LYS A 219
ILE A 220
LEU A 258
 None
 1.05A 4em2A-1hzvA:
0.0		 4em2A-1hzvA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5a CHEMOTAXIS PROTEIN
CHEA

(Thermotoga
maritima) 		PF02518
(HATPase_c) 		4 LYS A 511
ILE A 521
VAL A 533
LEU A 406
 None
 1.11A 4em2A-1i5aA:
undetectable		 4em2A-1i5aA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ix5 FKBP

(Methanothermococcus
thermolithotrophicus) 		PF00254
(FKBP_C) 		4 LYS A  10
ILE A  11
VAL A  65
LEU A  66
 None
 0.99A 4em2A-1ix5A:
undetectable		 4em2A-1ix5A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jxi PHOSPHOMETHYLPYRIMID
INE KINASE

(Salmonella
enterica) 		PF08543
(Phos_pyr_kin) 		4 LYS A  77
ILE A   9
VAL A  90
LEU A  94
 None
 1.04A 4em2A-1jxiA:
0.0		 4em2A-1jxiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2u OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Escherichia
coli) 		PF00215
(OMPdecase) 		4 ARG A  64
ILE A  68
VAL A  45
LEU A  21
 None
 1.11A 4em2A-1l2uA:
0.0		 4em2A-1l2uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mx3 C-TERMINAL BINDING
PROTEIN 1

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ARG A 337
ILE A 339
VAL A  48
LEU A  45
 None
 0.92A 4em2A-1mx3A:
0.2		 4em2A-1mx3A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o6d HYPOTHETICAL UPF0247
PROTEIN TM0844

(Thermotoga
maritima) 		PF02590
(SPOUT_MTase) 		4 LYS A  16
ILE A  19
VAL A 130
LEU A 131
 None
 1.06A 4em2A-1o6dA:
undetectable		 4em2A-1o6dA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 ILE A 462
VAL A 467
LYS A 423
LEU A 471
 None
 1.02A 4em2A-1opkA:
undetectable		 4em2A-1opkA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pv9 XAA-PRO DIPEPTIDASE

(Pyrococcus
furiosus) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 ARG A 235
ILE A 237
VAL A 324
LEU A 205
 None
 0.76A 4em2A-1pv9A:
undetectable		 4em2A-1pv9A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvb BETA-GLYCOSIDASE

(Thermosphaera
aggregans) 		PF00232
(Glyco_hydro_1) 		4 LYS A 372
ILE A 416
VAL A 418
LEU A 382
 None
 1.10A 4em2A-1qvbA:
undetectable		 4em2A-1qvbA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ARG B 127
ILE B 194
VAL B 256
LEU B 313
 None
 1.04A 4em2A-1skyB:
undetectable		 4em2A-1skyB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxd GA REPEAT BINDING
PROTEIN, ALPHA

(Mus musculus) 		PF02198
(SAM_PNT) 		4 ARG A 233
ILE A 210
VAL A 198
LEU A 195
 None
 0.86A 4em2A-1sxdA:
undetectable		 4em2A-1sxdA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0i YLR011WP

(Saccharomyces
cerevisiae) 		PF03358
(FMN_red) 		4 ARG A  25
LYS A  24
ILE A   5
VAL A  91
 None
 1.05A 4em2A-1t0iA:
undetectable		 4em2A-1t0iA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulz PYRUVATE CARBOXYLASE
N-TERMINAL DOMAIN

(Aquifex
aeolicus) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 ARG A 148
ILE A 150
VAL A 154
LEU A 198
 None
 1.10A 4em2A-1ulzA:
undetectable		 4em2A-1ulzA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8o BACTERIAL SIALIDASE

(Micromonospora
viridifaciens) 		PF00754
(F5_F8_type_C)
PF10633
(NPCBM_assoc)
PF13088
(BNR_2) 		4 ARG A 620
ILE A 564
VAL A 643
LEU A 504
 None
 1.09A 4em2A-1w8oA:
undetectable		 4em2A-1w8oA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w98 G1/S-SPECIFIC CYCLIN
E1

(Homo sapiens) 		PF00134
(Cyclin_N)
PF02984
(Cyclin_C) 		4 ARG B  98
VAL B 241
LYS B  88
LEU B 244
 None
 0.96A 4em2A-1w98B:
0.4		 4em2A-1w98B:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3o ACYL CARRIER PROTEIN

(Thermus
thermophilus) 		PF00550
(PP-binding) 		4 LYS A  76
ILE A   6
VAL A  10
LEU A  49
 None
 1.03A 4em2A-1x3oA:
undetectable		 4em2A-1x3oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1b 216AA LONG
HYPOTHETICAL
ALANYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		4 ARG A 201
LYS A 144
ILE A 147
LEU A 113
 None
 1.06A 4em2A-2e1bA:
0.9		 4em2A-2e1bA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcu 3-ISOPROPYLMALATE
DEHYDRATASE SMALL
SUBUNIT

(Streptococcus
mutans) 		PF00694
(Aconitase_C) 		4 ARG A  47
ILE A  60
VAL A  12
LEU A  72
 None
 1.10A 4em2A-2hcuA:
undetectable		 4em2A-2hcuA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k6g REPLICATION FACTOR C
SUBUNIT 1

(Homo sapiens) 		PF00533
(BRCT) 		4 ARG A 423
LYS A 427
ILE A 430
LEU A 475
 None
 0.96A 4em2A-2k6gA:
undetectable		 4em2A-2k6gA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ldx APO-LACTATE
DEHYDROGENASE

(Mus musculus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LYS A 316
ILE A 282
VAL A 276
LEU A 288
 None
 1.11A 4em2A-2ldxA:
undetectable		 4em2A-2ldxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mu0 ARSENATE REDUCTASE

(Brucella
abortus) 		PF03960
(ArsC) 		4 ARG A  76
ILE A 102
VAL A  65
LEU A  68
 None
 1.02A 4em2A-2mu0A:
undetectable		 4em2A-2mu0A:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nad NAD-DEPENDENT
FORMATE
DEHYDROGENASE

(Pseudomonas sp.
101) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ARG A 349
ILE A  94
VAL A   3
LEU A  70
 None
 0.88A 4em2A-2nadA:
undetectable		 4em2A-2nadA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1z RIBONUCLEOTIDE
REDUCTASE SUBUNIT R2

(Plasmodium
vivax) 		PF00268
(Ribonuc_red_sm) 		4 ARG A 183
ILE A 251
VAL A 247
LEU A 243
 None
 1.01A 4em2A-2o1zA:
0.8		 4em2A-2o1zA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q07 UNCHARACTERIZED
PROTEIN AF0587

(Archaeoglobus
fulgidus) 		PF01472
(PUA) 		4 LYS A 334
ILE A 337
VAL A 345
LEU A 263
 None
 0.80A 4em2A-2q07A:
undetectable		 4em2A-2q07A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r09 CYTOHESIN-3

(Mus musculus) 		PF00169
(PH)
PF01369
(Sec7) 		4 LYS A  82
ILE A  85
VAL A 101
LEU A 105
 None
 0.82A 4em2A-2r09A:
undetectable		 4em2A-2r09A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xro HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGV

(Pseudomonas
putida) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		4 LYS A 244
ILE A 247
VAL A  93
LEU A  97
 None
 0.67A 4em2A-2xroA:
7.9		 4em2A-2xroA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr1 3-DEHYDROQUINATE
DEHYDRATASE

(Geobacillus
kaustophilus) 		PF01487
(DHquinase_I) 		4 ARG A 167
ILE A 128
VAL A 144
LEU A 122
 None
 1.06A 4em2A-2yr1A:
undetectable		 4em2A-2yr1A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 ARG X 748
ILE X 682
VAL X 684
LEU X 791
 None
 1.11A 4em2A-2zkmX:
undetectable		 4em2A-2zkmX:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a27 UNCHARACTERIZED
PROTEIN MJ1557

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		4 LYS A  57
ILE A  35
VAL A  11
LEU A  37
 None
 0.99A 4em2A-3a27A:
undetectable		 4em2A-3a27A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3act CELLOBIOSE
PHOSPHORYLASE

(Cellulomonas
gilvus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 ARG A 749
ILE A 781
VAL A 820
LEU A 795
 None
 0.87A 4em2A-3actA:
undetectable		 4em2A-3actA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 ARG A   3
ILE A  10
VAL A  28
LEU A  23
 None
 1.05A 4em2A-3b02A:
5.8		 4em2A-3b02A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b3l KETOHEXOKINASE

(Homo sapiens) 		PF00294
(PfkB) 		4 ARG A 152
ILE A 138
VAL A   9
LEU A   7
 None
 0.96A 4em2A-3b3lA:
undetectable		 4em2A-3b3lA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bm3 PSPGI RESTRICTION
ENDONUCLEASE

(Pyrococcus sp.
GI-H) 		PF09019
(EcoRII-C) 		4 LYS A 126
ILE A 127
LYS A 136
LEU A 177
 None
 1.11A 4em2A-3bm3A:
undetectable		 4em2A-3bm3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ca9 DEOXYURIDINE
TRIPHOSPHATASE

(Paramecium
bursaria
Chlorella virus
IL3A) 		PF00692
(dUTPase) 		4 ARG A  63
ILE A  60
VAL A  89
LEU A  91
 None
DUD  A 777 ( 4.9A)
None
None
 0.94A 4em2A-3ca9A:
undetectable		 4em2A-3ca9A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cph RAS-RELATED PROTEIN
SEC4

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		4 LYS A 178
ILE A  64
VAL A  62
LEU A  71
 None
 0.96A 4em2A-3cphA:
undetectable		 4em2A-3cphA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d2z N-ACETYLMURAMOYL-L-A
LANINE AMIDASE AMID

(Escherichia
coli) 		PF01510
(Amidase_2) 		4 LYS A 135
ILE A 138
VAL A 148
LEU A  32
 None
 0.99A 4em2A-3d2zA:
undetectable		 4em2A-3d2zA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkt MARITIMACIN

(Thermotoga
maritima) 		PF04454
(Linocin_M18) 		4 ARG A  27
ILE A  29
VAL A 111
LEU A 107
 None
 1.02A 4em2A-3dktA:
undetectable		 4em2A-3dktA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcj NITROALKANE OXIDASE

(Fusarium
oxysporum) 		PF00441
(Acyl-CoA_dh_1)
PF02771
(Acyl-CoA_dh_N) 		4 LYS A 118
ILE A 121
VAL A  62
LEU A 101
 None
 1.09A 4em2A-3fcjA:
1.4		 4em2A-3fcjA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flo DNA POLYMERASE ALPHA
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		4 ARG A 642
ILE A 650
VAL A 700
LEU A 702
 None
 1.06A 4em2A-3floA:
undetectable		 4em2A-3floA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fn4 NAD-DEPENDENT
FORMATE
DEHYDROGENASE

(Moraxella sp.) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ARG A 349
ILE A  94
VAL A   3
LEU A  70
 None
 0.89A 4em2A-3fn4A:
undetectable		 4em2A-3fn4A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftj MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		PF12704
(MacB_PCD) 		4 LYS A 419
ILE A 422
VAL A 369
LYS A 431
 None
 1.02A 4em2A-3ftjA:
undetectable		 4em2A-3ftjA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'

(Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 ARG A 380
ILE A 407
VAL A 365
LEU A 388
 None
 1.03A 4em2A-3hkzA:
undetectable		 4em2A-3hkzA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hlt HDHD2

(Homo sapiens) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 ARG A  80
ILE A 143
VAL A 114
LEU A  92
 None
 1.08A 4em2A-3hltA:
undetectable		 4em2A-3hltA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7m XAA-PRO DIPEPTIDASE

(Lactobacillus
brevis) 		PF01321
(Creatinase_N) 		4 LYS A   2
ILE A   7
VAL A  46
LEU A  44
 None
 1.12A 4em2A-3i7mA:
undetectable		 4em2A-3i7mA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		4 ARG W 684
ILE W1002
VAL W 434
LEU W1008
 None
 1.06A 4em2A-3iylW:
undetectable		 4em2A-3iylW:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF19
PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
no annotation 		4 ARG c 537
ILE A1499
VAL A1505
LEU A1346
 None
 1.00A 4em2A-3jb9c:
undetectable		 4em2A-3jb9c:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k3p D-ALANINE--D-ALANINE
LIGASE

(Streptococcus
mutans) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG A  29
ILE A  31
VAL A  38
LEU A   8
 None
 0.87A 4em2A-3k3pA:
undetectable		 4em2A-3k3pA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nns DNA BINDING RESPONSE
REGULATOR B

(Thermotoga
maritima) 		PF00072
(Response_reg) 		4 ARG A  63
ILE A  65
VAL A  74
LEU A  49
 None
 1.05A 4em2A-3nnsA:
undetectable		 4em2A-3nnsA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		4 LYS A 700
ILE A 939
VAL A 926
LEU A 718
 None
 1.10A 4em2A-3o8oA:
undetectable		 4em2A-3o8oA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE

(Saccharomyces
cerevisiae) 		PF00692
(dUTPase) 		4 ARG A  68
ILE A  65
VAL A  94
LEU A  96
 DUP  A 148 (-3.8A)
None
None
None
 1.04A 4em2A-3p48A:
undetectable		 4em2A-3p48A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6v BETA-LACTAMASE

(Serratia
fonticola) 		PF00753
(Lactamase_B) 		4 LYS A 250
ILE A 253
VAL A 256
LEU A 217
 None
 1.10A 4em2A-3q6vA:
undetectable		 4em2A-3q6vA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7t ADENYLOSUCCINATE
SYNTHETASE

(Campylobacter
jejuni) 		PF00709
(Adenylsucc_synt) 		4 ILE A 286
VAL A 330
LYS A 263
LEU A 331
 None
 1.04A 4em2A-3r7tA:
undetectable		 4em2A-3r7tA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rle GOLGI
REASSEMBLY-STACKING
PROTEIN 2

(Homo sapiens) 		PF04495
(GRASP55_65) 		4 LYS A   7
ILE A   9
VAL A  41
LEU A  70
 None
 0.97A 4em2A-3rleA:
undetectable		 4em2A-3rleA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ros NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Lactobacillus
acidophilus) 		PF00171
(Aldedh) 		4 LYS A 319
ILE A 322
VAL A 328
LEU A 347
 None
 1.06A 4em2A-3rosA:
undetectable		 4em2A-3rosA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufa SERINE PROTEASE SPLA

(Staphylococcus
aureus) 		PF00089
(Trypsin) 		4 LYS A 191
ILE A 194
VAL A  35
LEU A  79
 None
 1.00A 4em2A-3ufaA:
undetectable		 4em2A-3ufaA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufi HYPOTHETICAL PROTEIN
BACOVA_04980

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 LYS A  37
ILE A 111
VAL A  71
LEU A 121
 MLY  A  36 (-3.0A)
None
None
None
 1.08A 4em2A-3ufiA:
undetectable		 4em2A-3ufiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vyw MNMC2

(Aquifex
aeolicus) 		PF05430
(Methyltransf_30) 		4 LYS A 213
ILE A 216
VAL A 190
LEU A 101
 None
 1.12A 4em2A-3vywA:
undetectable		 4em2A-3vywA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdp NUCLEOCAPSID PROTEIN

(Influenza A
virus) 		PF00506
(Flu_NP) 		4 ILE A  57
VAL A 329
LYS A 325
LEU A 381
 None
 1.06A 4em2A-3zdpA:
undetectable		 4em2A-3zdpA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpj TON_1535

(Thermococcus
onnurineus) 		no annotation 4 LYS A  22
ILE A   7
VAL A  35
LEU A  36
 None
 1.05A 4em2A-3zpjA:
undetectable		 4em2A-3zpjA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dzj GENE 1 PROTEIN

(Shigella virus
Sf6) 		no annotation 4 ARG A  67
ILE A  21
VAL A  46
LEU A  50
 None
 0.98A 4em2A-4dzjA:
undetectable		 4em2A-4dzjA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e09 PLASMID PARTITIONING
PROTEIN PARF

(Escherichia
coli) 		PF01656
(CbiA) 		4 ARG A 134
ILE A 103
VAL A 119
LEU A 122
 None
 0.97A 4em2A-4e09A:
undetectable		 4em2A-4e09A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e3z PUTATIVE
OXIDOREDUCTASE
PROTEIN

(Rhizobium etli) 		PF13561
(adh_short_C2) 		4 ARG A 127
ILE A 182
VAL A 177
LEU A 173
 None
 1.05A 4em2A-4e3zA:
undetectable		 4em2A-4e3zA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyy ICMQ
ICMR

(Legionella
pneumophila) 		PF09475
(Dot_icm_IcmQ)
no annotation 		4 ARG Q  43
ILE R  41
VAL R  79
LEU R  75
 None
 1.11A 4em2A-4eyyQ:
undetectable		 4em2A-4eyyQ:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5u PROBABLE HYDROLASE
NIT2

(Saccharomyces
cerevisiae) 		PF00795
(CN_hydrolase) 		4 LYS A  27
ILE A  30
VAL A  88
LEU A  43
 None
 1.10A 4em2A-4h5uA:
undetectable		 4em2A-4h5uA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hnh NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Veillonella
parvula) 		PF13460
(NAD_binding_10) 		4 ARG A  40
ILE A  46
VAL A  53
LEU A  32
 NAP  A 301 (-3.0A)
None
None
None
 1.11A 4em2A-4hnhA:
undetectable		 4em2A-4hnhA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsc STREPTOLYSIN O

(Streptococcus
pyogenes) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 LYS X 290
ILE X 285
VAL X 257
LYS X 351
 None
 1.06A 4em2A-4hscX:
undetectable		 4em2A-4hscX:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwj TRNA
(GUANINE(9)-N1)-METH
YLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF01746
(tRNA_m1G_MT) 		4 ARG A 127
ILE A 135
VAL A 252
LEU A 256
 TRS  A 303 (-3.0A)
None
None
None
 1.10A 4em2A-4jwjA:
undetectable		 4em2A-4jwjA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq8 CYTOCHROME P450 19A1

(Homo sapiens) 		PF00067
(p450) 		4 ARG A 457
ILE A 450
VAL A 194
LEU A 190
 None
 1.10A 4em2A-4kq8A:
1.2		 4em2A-4kq8A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqx KETOL-ACID
REDUCTOISOMERASE

(Slackia exigua) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 ARG A 148
ILE A  32
VAL A  53
LEU A  72
 None
 1.08A 4em2A-4kqxA:
undetectable		 4em2A-4kqxA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m9d ADENYLOSUCCINATE
SYNTHETASE

(Bacillus
anthracis) 		PF00709
(Adenylsucc_synt) 		4 ILE A 289
VAL A 333
LYS A 266
LEU A 334
 None
 1.01A 4em2A-4m9dA:
undetectable		 4em2A-4m9dA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n72 PYRUVATE
DEHYDROGENASE
(DIHYDROLIPOYLTRANSA
CETYLASE COMPONENT)

(Escherichia
coli) 		PF00198
(2-oxoacid_dh) 		4 ARG A 440
ILE A 462
VAL A 574
LEU A 594
 None
 1.07A 4em2A-4n72A:
undetectable		 4em2A-4n72A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsx U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN 21

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 LYS A 245
ILE A 246
VAL A 266
LEU A 264
 None
 1.08A 4em2A-4nsxA:
undetectable		 4em2A-4nsxA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqg GLYCOSYLTRANSFERASE
GTF1

(Streptococcus
pneumoniae) 		PF00534
(Glycos_transf_1) 		4 LYS A 460
ILE A 421
VAL A 396
LEU A 323
 None
 0.99A 4em2A-4pqgA:
undetectable		 4em2A-4pqgA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q53 UNCHARACTERIZED
PROTEIN

(Bacteroides
uniformis) 		PF16022
(DUF4783) 		4 ILE A 120
VAL A  48
LYS A  61
LEU A  50
 CSO  A 109 ( 3.6A)
None
None
None
 1.04A 4em2A-4q53A:
undetectable		 4em2A-4q53A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm7 ACYL-COA
DEHYDROGENASE

(Slackia
heliotrinireducens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ARG A 266
ILE A 337
VAL A 281
LEU A 285
 None
 1.10A 4em2A-4rm7A:
1.0		 4em2A-4rm7A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4to8 FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE,
CLASS II

(Staphylococcus
aureus) 		PF01116
(F_bP_aldolase) 		4 LYS A  94
ILE A  97
VAL A 104
LEU A  84
 None
 1.09A 4em2A-4to8A:
undetectable		 4em2A-4to8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye2 CAPPING ENZYME
PROTEIN

(Rotavirus A) 		PF05213
(Corona_NS2A) 		4 ILE A 731
VAL A 830
LYS A 824
LEU A 822
 None
 0.94A 4em2A-4ye2A:
undetectable		 4em2A-4ye2A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yrd CAPSULAR
POLYSACCHARIDE
SYNTHESIS ENZYME
CAP5F

(Staphylococcus
aureus) 		PF01370
(Epimerase) 		4 LYS A 181
ILE A 184
VAL A  51
LEU A  90
 None
 0.93A 4em2A-4yrdA:
undetectable		 4em2A-4yrdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3) 		4 LYS A 289
ILE A 292
VAL A 302
LYS A   5
 None
 1.04A 4em2A-5bzaA:
undetectable		 4em2A-5bzaA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwz 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Pseudomonas
aeruginosa) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 ARG C 137
ILE C  81
VAL C 151
LEU C 182
 None
 1.01A 4em2A-5dwzC:
undetectable		 4em2A-5dwzC:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ed1 DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1

(Homo sapiens) 		PF02137
(A_deamin) 		4 ARG A 563
ILE A 567
VAL A 525
LEU A 675
 None
 1.11A 4em2A-5ed1A:
undetectable		 4em2A-5ed1A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm2 3C PROTEINASE

(Foot-and-mouth
disease virus) 		PF00548
(Peptidase_C3) 		4 LYS A 203
ILE A 206
VAL A  89
LEU A  87
 None
 1.09A 4em2A-5hm2A:
undetectable		 4em2A-5hm2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 LYS A 120
ILE A 123
VAL A 129
LEU A 107
 None
 1.01A 4em2A-5hs0A:
undetectable		 4em2A-5hs0A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwb TYPE II
NADH:UBIQUINONE
OXIDOREDUCTASE

(Plasmodium
falciparum) 		PF07992
(Pyr_redox_2) 		4 ILE A 454
VAL A 449
LYS A 338
LEU A 446
 None
 1.11A 4em2A-5jwbA:
undetectable		 4em2A-5jwbA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0y EUKARYOTIC
INITIATION FACTOR 2
GAMMA SUBUNIT
(EIF2-GAMMA)

(Oryctolagus
cuniculus) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF09173
(eIF2_C) 		4 LYS S 439
ILE S 440
VAL S 419
LEU S 456
 None
 0.90A 4em2A-5k0yS:
undetectable		 4em2A-5k0yS:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfq BETA-LACTAMASE

(Bacteroides
cellulosilyticus) 		PF13354
(Beta-lactamase2) 		4 LYS A   6
ILE A   9
VAL A 271
LEU A 275
 None
 0.87A 4em2A-5tfqA:
undetectable		 4em2A-5tfqA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tla UBIQUITIN-LIKE
PROTEIN ISG15

(Mus musculus) 		PF00240
(ubiquitin) 		4 LYS A  29
ILE A  32
VAL A   7
LEU A   5
 None
 0.96A 4em2A-5tlaA:
undetectable		 4em2A-5tlaA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1e ICMO (DOTL)
ICMW

(Legionella
pneumophila) 		no annotation 4 ARG C 771
LYS B  58
VAL B  92
LEU B  61
 None
 0.67A 4em2A-5x1eC:
undetectable		 4em2A-5x1eC:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2g CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Campylobacter
jejuni) 		no annotation 4 ARG A 128
ILE A 195
VAL A 162
LEU A 166
 A  B  45 ( 3.3A)
None
None
None
 0.95A 4em2A-5x2gA:
undetectable		 4em2A-5x2gA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6t ENDO-1,4-BETA-MANNAN
ASE

(Eisenia fetida) 		no annotation 4 ILE A 235
VAL A  22
LYS A 303
LEU A  27
 None
 1.03A 4em2A-5y6tA:
undetectable		 4em2A-5y6tA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bbp CYTOHESIN-3,ADP-RIBO
SYLATION FACTOR 6

(Homo sapiens;
Mus musculus) 		no annotation 4 LYS A  82
ILE A  85
VAL A 101
LEU A 105
 None
 0.82A 4em2A-6bbpA:
undetectable		 4em2A-6bbpA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bs7 ADENYLOSUCCINATE
SYNTHETASE

(Legionella
pneumophila) 		no annotation 4 ILE A 291
VAL A 335
LYS A 268
LEU A 336
 None
 1.03A 4em2A-6bs7A:
undetectable		 4em2A-6bs7A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejj WLAC PROTEIN

(Campylobacter
jejuni) 		no annotation 4 ARG A 191
ILE A 189
VAL A 272
LEU A 262
 UDP  A 401 (-3.5A)
None
UDP  A 401 (-4.3A)
None
 1.10A 4em2A-6ejjA:
undetectable		 4em2A-6ejjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gc6 50S RIBOSOMAL
PROTEIN L2

(Escherichia
coli) 		no annotation 4 ARG C 188
ILE C 134
VAL C 140
LEU C 191
 None
 1.06A 4em2A-6gc6C:
undetectable		 4em2A-6gc6C:
17.24