SIMILAR PATTERNS OF AMINO ACIDS FOR 4EM2_A_SALA502_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a27 17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		4 THR A 118
LEU A 122
VAL A 137
VAL A 139
 None
 0.88A 4em2A-1a27A:
0.0		 4em2A-1a27A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ar1 CYTOCHROME C OXIDASE

(Paracoccus
denitrificans) 		PF00116
(COX2)
PF02790
(COX2_TM) 		4 LEU B   4
TRP B 242
VAL B 163
GLN B 236
 None
 1.01A 4em2A-1ar1B:
undetectable		 4em2A-1ar1B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bjn PHOSPHOSERINE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00266
(Aminotran_5) 		4 TYR A 148
LEU A 139
VAL A 169
VAL A 171
 None
 0.90A 4em2A-1bjnA:
0.0		 4em2A-1bjnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bry BRYODIN I

(Bryonia dioica) 		PF00161
(RIP) 		4 THR Y  48
LEU Y  25
VAL Y  69
VAL Y  64
 None
 1.00A 4em2A-1bryY:
0.0		 4em2A-1bryY:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eiz FTSJ

(Escherichia
coli) 		PF01728
(FtsJ) 		4 THR A 205
LEU A  48
ARG A 188
VAL A 162
 None
 0.88A 4em2A-1eizA:
0.0		 4em2A-1eizA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1esr MONOCYTE CHEMOTACTIC
PROTEIN 2

(Homo sapiens) 		PF00048
(IL8) 		4 THR A  45
LEU A  25
ARG A  18
VAL A  51
 None
 0.91A 4em2A-1esrA:
undetectable		 4em2A-1esrA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fdw 17-BETA-HYDROXYSTERO
ID DEHYDROGENASE

(Homo sapiens) 		PF00106
(adh_short) 		4 THR A 118
LEU A 122
VAL A 137
VAL A 139
 None
 0.79A 4em2A-1fdwA:
0.0		 4em2A-1fdwA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1he3 BILIVERDIN IX BETA
REDUCTASE

(Homo sapiens) 		PF13460
(NAD_binding_10) 		4 THR A  12
LEU A  20
VAL A  32
VAL A  34
 NAP  A1206 (-3.3A)
None
None
None
 0.86A 4em2A-1he3A:
0.0		 4em2A-1he3A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkh GAMMA LACTAMASE

(Microbacterium) 		PF00561
(Abhydrolase_1) 		4 LEU A  28
VAL A  95
VAL A  93
GLN A  24
 None
 0.99A 4em2A-1hkhA:
0.0		 4em2A-1hkhA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hlg LIPASE, GASTRIC

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 THR A 188
LEU A 326
VAL A 182
VAL A 185
 None
 1.01A 4em2A-1hlgA:
0.0		 4em2A-1hlgA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1h PRECORRIN-8X
METHYLMUTASE

(Pseudomonas
denitrificans
(nomen
rejiciendum)) 		PF02570
(CbiC) 		4 THR A  51
LEU A  27
VAL A  39
VAL A  42
 None
 0.99A 4em2A-1i1hA:
0.0		 4em2A-1i1hA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jbj CD3 EPSILON AND
GAMMA ECTODOMAIN
FRAGMENT COMPLEX

(Mus musculus) 		PF16680
(Ig_4)
PF16681
(Ig_5) 		4 TYR A 184
LEU A 180
VAL A 114
VAL A 116
 None
 1.00A 4em2A-1jbjA:
undetectable		 4em2A-1jbjA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1

(Hordeum vulgare) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 THR A 131
LEU A 180
VAL A 135
GLN A 100
 None
 0.95A 4em2A-1lq2A:
0.6		 4em2A-1lq2A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvf SYNTAXIN 6

(Rattus
norvegicus) 		PF09177
(Syntaxin-6_N) 		4 LEU A  61
VAL A  14
VAL A  18
GLN A  22
 None
 0.98A 4em2A-1lvfA:
undetectable		 4em2A-1lvfA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus gallus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 TYR C  32
THR C  36
LEU C  40
VAL B  98
 None
 0.91A 4em2A-1m1jC:
undetectable		 4em2A-1m1jC:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE

(Equine
arteritis virus) 		PF05579
(Peptidase_S32) 		4 LEU A  58
VAL A  34
VAL A  32
GLN A  73
 None
 0.80A 4em2A-1mbmA:
undetectable		 4em2A-1mbmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1npr TRANSCRIPTION
ANTITERMINATION
PROTEIN NUSG

(Aquifex
aeolicus) 		PF00467
(KOW)
PF02357
(NusG)
PF07009
(NusG_II) 		5 TYR A 138
LEU A 172
VAL A 170
VAL A 163
GLN A  17
 None
 1.11A 4em2A-1nprA:
undetectable		 4em2A-1nprA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p1v SUPEROXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 LEU A  84
VAL A  31
VAL A  29
GLN A  22
 None
 0.91A 4em2A-1p1vA:
undetectable		 4em2A-1p1vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1to5 SUPEROXIDE DISMUTASE

(Schistosoma
mansoni) 		PF00080
(Sod_Cu) 		4 LEU A  83
VAL A  30
VAL A  28
GLN A  21
 None
 0.97A 4em2A-1to5A:
undetectable		 4em2A-1to5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ARP2/3 COMPLEX 20KDA
SUBUNIT

(Bos taurus) 		PF05856
(ARPC4) 		4 TYR F   8
LEU F  16
VAL F  72
VAL F  61
 None
 0.79A 4em2A-1u2vF:
0.9		 4em2A-1u2vF:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 TYR A 221
LEU A 272
VAL A 214
VAL A 216
 None
 0.88A 4em2A-1ut9A:
undetectable		 4em2A-1ut9A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq7 50S RIBOSOMAL
PROTEIN L30P

(Haloarcula
marismortui) 		PF00327
(Ribosomal_L30) 		4 THR W  88
LEU W 112
VAL W  79
VAL W  84
 None
 1.00A 4em2A-1vq7W:
undetectable		 4em2A-1vq7W:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w3b UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110

(Homo sapiens) 		PF00515
(TPR_1)
PF13181
(TPR_8)
PF13414
(TPR_11)
PF13424
(TPR_12) 		4 LEU A 157
VAL A 133
VAL A 137
GLN A 141
 None
 0.69A 4em2A-1w3bA:
undetectable		 4em2A-1w3bA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xso COPPER,ZINC
SUPEROXIDE DISMUTASE

(Xenopus laevis) 		PF00080
(Sod_Cu) 		4 LEU A  82
VAL A  29
VAL A  27
GLN A  22
 None
 0.90A 4em2A-1xsoA:
undetectable		 4em2A-1xsoA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yox HYPOTHETICAL PROTEIN
PA3696

(Pseudomonas
aeruginosa) 		PF01987
(AIM24) 		4 LEU A 110
TRP A 219
VAL A 101
VAL A 157
 None
 1.00A 4em2A-1yoxA:
undetectable		 4em2A-1yoxA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b24 NAPHTHALENE
DIOXYGENASE SMALL
SUBUNIT

(Rhodococcus sp.
NCIMB 12038) 		PF00866
(Ring_hydroxyl_B) 		5 TYR B 527
THR B 523
ARG B 645
VAL B 622
VAL B 609
 None
 1.39A 4em2A-2b24B:
undetectable		 4em2A-2b24B:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ekm HYPOTHETICAL PROTEIN
ST1511

(Sulfurisphaera
tokodaii) 		PF04008
(Adenosine_kin) 		4 TYR A  87
THR A  74
VAL A 119
VAL A  10
 None
 0.92A 4em2A-2ekmA:
undetectable		 4em2A-2ekmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hne L-FUCONATE
DEHYDRATASE

(Xanthomonas
campestris) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 357
ARG A 327
VAL A  53
GLN A  63
 None
 0.96A 4em2A-2hneA:
undetectable		 4em2A-2hneA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jis CYSTEINE SULFINIC
ACID DECARBOXYLASE

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 113
LEU A 111
VAL A 360
GLN A 115
 None
 0.86A 4em2A-2jisA:
0.0		 4em2A-2jisA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k0m UNCHARACTERIZED
PROTEIN

(Rhodospirillum
rubrum) 		PF11523
(DUF3223) 		4 LEU A  45
VAL A  37
VAL A  68
GLN A  76
 None
 0.94A 4em2A-2k0mA:
undetectable		 4em2A-2k0mA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k0r THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBD

(Neisseria
meningitidis) 		PF11412
(DsbC) 		4 TYR A  93
THR A  47
VAL A  28
VAL A  26
 None
 0.89A 4em2A-2k0rA:
undetectable		 4em2A-2k0rA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkx BIFUNCTIONAL PROTEIN
GLMU

(Mycobacterium
tuberculosis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		4 THR A 341
LEU A 343
VAL A 361
VAL A 359
 None
 1.00A 4em2A-2qkxA:
undetectable		 4em2A-2qkxA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr6 IMP
DEHYDROGENASE/GMP
REDUCTASE

(Corynebacterium
glutamicum) 		PF00478
(IMPDH) 		4 THR A 109
TRP A 303
VAL A  96
GLN A 105
 None
 0.86A 4em2A-2qr6A:
undetectable		 4em2A-2qr6A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x05 EXO-BETA-D-GLUCOSAMI
NIDASE

(Amycolatopsis
orientalis) 		PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 127
VAL A 184
VAL A 151
GLN A 176
 None
 0.89A 4em2A-2x05A:
undetectable		 4em2A-2x05A:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans) 		PF07971
(Glyco_hydro_92) 		4 TYR A 149
LEU A 238
VAL A 161
VAL A  81
 None
 0.92A 4em2A-2xsgA:
undetectable		 4em2A-2xsgA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvn ASPERGILLUS
FUMIGATUS CHITINASE
A1

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		4 TYR A 327
LEU A 335
VAL A 295
VAL A 291
 None
 0.62A 4em2A-2xvnA:
undetectable		 4em2A-2xvnA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwu IMPORTIN13

(Homo sapiens) 		PF03810
(IBN_N)
PF08389
(Xpo1) 		4 LEU B 170
VAL B 143
VAL B 147
GLN B 151
 None
 0.96A 4em2A-2xwuB:
undetectable		 4em2A-2xwuB:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy4 ZINC ABC
TRANSPORTER,
PERIPLASMIC
ZINC-BINDING PROTEIN

(Salmonella
enterica) 		PF01297
(ZnuA) 		4 LEU A  52
VAL A  29
VAL A  78
GLN A 101
 None
 1.01A 4em2A-2xy4A:
0.3		 4em2A-2xy4A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0b PHOTOSYSTEM II
REACTION CENTER
PROTEIN K
PHOTOSYSTEM II
REACTION CENTER
PROTEIN YCF12

(Thermosynechococcus
vulcanus) 		PF02533
(PsbK)
PF05969
(PSII_Ycf12) 		4 LEU K  31
VAL K  27
VAL K  24
GLN Y  21
 BCR  K1051 ( 4.4A)
None
None
None
 1.00A 4em2A-3a0bK:
undetectable		 4em2A-3a0bK:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3biw NEUROLIGIN-1

(Rattus
norvegicus) 		PF00135
(COesterase) 		4 LEU A 211
VAL A 142
VAL A 146
GLN A 149
 None
 1.01A 4em2A-3biwA:
undetectable		 4em2A-3biwA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bs8 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Bacillus
subtilis) 		PF00202
(Aminotran_3) 		4 LEU A 315
VAL A 102
VAL A 106
GLN A 254
 None
 0.98A 4em2A-3bs8A:
undetectable		 4em2A-3bs8A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzj UV ENDONUCLEASE

(Thermus
thermophilus) 		PF03851
(UvdE) 		4 LEU A 229
ARG A  58
VAL A 139
VAL A 141
 None
 1.00A 4em2A-3bzjA:
undetectable		 4em2A-3bzjA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0k UPF0064 PROTEIN YCCW

(Escherichia
coli) 		PF10672
(Methyltrans_SAM) 		4 LEU A 283
VAL A 276
VAL A 247
GLN A 245
 None
 0.92A 4em2A-3c0kA:
undetectable		 4em2A-3c0kA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8z CYSTEINYL-TRNA
SYNTHETASE

(Mycolicibacterium
smegmatis) 		PF01406
(tRNA-synt_1e) 		4 LEU A 412
TRP A 343
VAL A 404
VAL A 400
 None
 0.97A 4em2A-3c8zA:
undetectable		 4em2A-3c8zA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce1 SUPEROXIDE DISMUTASE
[CU-ZN]

(Naganishia
liquefaciens) 		PF00080
(Sod_Cu) 		4 LEU A  88
VAL A  34
VAL A  32
GLN A  25
 None
 0.88A 4em2A-3ce1A:
undetectable		 4em2A-3ce1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7a UPF0201 PROTEIN
PH1010

(Pyrococcus
horikoshii) 		PF01877
(RNA_binding) 		4 THR A  51
LEU A  34
VAL A  10
VAL A   8
 None
 0.93A 4em2A-3d7aA:
undetectable		 4em2A-3d7aA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhw METHIONINE IMPORT
ATP-BINDING PROTEIN
METN

(Escherichia
coli) 		PF00005
(ABC_tran)
PF09383
(NIL) 		4 TYR C  34
LEU C  47
VAL C  24
GLN C 222
 None
 0.98A 4em2A-3dhwC:
undetectable		 4em2A-3dhwC:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ers TRNA-BINDING PROTEIN
YGJH

(Escherichia
coli) 		PF01588
(tRNA_bind) 		4 THR X  47
LEU X  83
VAL X  36
VAL X  34
 None
 0.97A 4em2A-3ersX:
undetectable		 4em2A-3ersX:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fi9 MALATE DEHYDROGENASE

(Porphyromonas
gingivalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 THR A 174
LEU A 198
VAL A 193
VAL A 171
 None
 0.89A 4em2A-3fi9A:
undetectable		 4em2A-3fi9A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0k PUTATIVE MEMBRANE
PROTEIN

(Novosphingobium
aromaticivorans) 		PF12680
(SnoaL_2) 		4 TYR A  18
THR A  84
VAL A  86
GLN A  68
 MPD  A 133 ( 4.9A)
None
None
MPD  A 134 (-3.4A)
 0.91A 4em2A-3g0kA:
undetectable		 4em2A-3g0kA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gas HEME OXYGENASE

(Helicobacter
pylori) 		PF01243
(Putative_PNPOx)
PF10615
(DUF2470) 		4 THR A 173
LEU A 213
VAL A 149
VAL A 147
 None
 0.76A 4em2A-3gasA:
undetectable		 4em2A-3gasA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k28 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
2

(Bacillus
anthracis) 		PF00202
(Aminotran_3) 		4 LEU A 315
VAL A 102
VAL A 106
GLN A 254
 None
 0.82A 4em2A-3k28A:
undetectable		 4em2A-3k28A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4z GLYCOSIDE HYDROLASE
FAMILY 9

(Ruminiclostridium
thermocellum) 		PF02018
(CBM_4_9)
PF02927
(CelD_N) 		4 TYR A 195
LEU A 246
VAL A 188
VAL A 190
 None
 0.92A 4em2A-3k4zA:
undetectable		 4em2A-3k4zA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kwu MUNC13-1

(Rattus
norvegicus) 		PF00168
(C2) 		4 THR A 781
LEU A 798
VAL A 755
VAL A 753
 None
 0.77A 4em2A-3kwuA:
undetectable		 4em2A-3kwuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l9y SUPEROXIDE DISMUTASE
[CU-ZN]

(Bombyx mori) 		PF00080
(Sod_Cu) 		4 LEU A  83
VAL A  30
VAL A  28
GLN A  21
 None
 0.92A 4em2A-3l9yA:
undetectable		 4em2A-3l9yA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1c ENVELOPE
GLYCOPROTEIN H

(Human
alphaherpesvirus
2) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 THR A 551
LEU A 548
VAL A 733
VAL A 746
 None
 0.86A 4em2A-3m1cA:
1.5		 4em2A-3m1cA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mnd SUPEROXIDE DISMUTASE
[CU-ZN]

(Taenia solium) 		PF00080
(Sod_Cu) 		4 LEU A  81
VAL A  28
VAL A  26
GLN A  21
 None
 0.87A 4em2A-3mndA:
undetectable		 4em2A-3mndA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odw RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1

(Homo sapiens) 		PF00621
(RhoGEF) 		4 LEU A 740
VAL A 668
VAL A 666
GLN A 679
 None
 0.95A 4em2A-3odwA:
undetectable		 4em2A-3odwA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps5 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 6

(Homo sapiens) 		PF00017
(SH2)
PF00102
(Y_phosphatase) 		4 TYR A 505
ARG A 109
VAL A 218
GLN A 485
 None
 0.79A 4em2A-3ps5A:
undetectable		 4em2A-3ps5A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz2 GERANYLGERANYL
TRANSFERASE TYPE-2
SUBUNIT BETA

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		5 TYR B  51
THR B  55
LEU B  59
VAL B 309
GLN B 103
 None
None
None
None
GRG  B 334 (-3.6A)
 1.45A 4em2A-3pz2B:
undetectable		 4em2A-3pz2B:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6d PROLINE DIPEPTIDASE

(Bacillus
anthracis) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 THR A 285
VAL A 313
VAL A 315
GLN A 248
 None
 0.87A 4em2A-3q6dA:
undetectable		 4em2A-3q6dA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qcv LT3015 ANTIBODY FAB
FRAGMENT, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU H  18
ARG H  38
VAL H 109
VAL H 111
 None
 0.95A 4em2A-3qcvH:
undetectable		 4em2A-3qcvH:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qm2 PHOSPHOSERINE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF00266
(Aminotran_5) 		4 TYR A 148
LEU A 139
VAL A 169
VAL A 171
 None
 0.95A 4em2A-3qm2A:
undetectable		 4em2A-3qm2A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhc GLUTAREDOXIN-C5,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00462
(Glutaredoxin) 		4 THR A  90
LEU A  99
VAL A  79
VAL A  77
 None
 0.87A 4em2A-3rhcA:
undetectable		 4em2A-3rhcA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpf MOLYBDOPTERIN
SYNTHASE CATALYTIC
SUBUNIT

(Helicobacter
pylori) 		PF02391
(MoaE) 		4 THR A  11
LEU A  15
VAL A  32
VAL A  34
 None
 0.95A 4em2A-3rpfA:
undetectable		 4em2A-3rpfA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrw THYLAKOID LUMENAL 29
KDA PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00141
(peroxidase) 		4 LEU A 188
VAL A 212
VAL A 216
GLN A 220
 None
 0.63A 4em2A-3rrwA:
1.0		 4em2A-3rrwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4w FANCONI ANEMIA GROUP
D2 PROTEIN HOMOLOG

(Mus musculus) 		PF14631
(FancD2) 		4 LEU B 813
ARG B 791
VAL B 794
VAL B 930
 None
 0.95A 4em2A-3s4wB:
undetectable		 4em2A-3s4wB:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5n 4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00701
(DHDPS) 		4 LEU A 160
VAL A 119
VAL A 123
GLN A 127
 None
 0.87A 4em2A-3s5nA:
undetectable		 4em2A-3s5nA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tev GLYCOSYL HYROLASE,
FAMILY 3

(Deinococcus
radiodurans) 		PF00933
(Glyco_hydro_3) 		4 LEU A 280
VAL A 303
VAL A 307
GLN A 311
 None
 0.73A 4em2A-3tevA:
undetectable		 4em2A-3tevA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujp MN TRANSPORTER
SUBUNIT

(Synechocystis
sp. PCC 6803) 		PF01297
(ZnuA) 		4 LEU A 108
VAL A  57
VAL A  78
GLN A  69
 None
 0.94A 4em2A-3ujpA:
undetectable		 4em2A-3ujpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va7 KLLA0E08119P

(Kluyveromyces
lactis) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02626
(CT_A_B)
PF02682
(CT_C_D)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 THR A 695
LEU A 628
VAL A 653
VAL A 671
 None
 0.99A 4em2A-3va7A:
undetectable		 4em2A-3va7A:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 LEU A1831
TRP A1906
ARG A1911
VAL A1827
 None
 0.97A 4em2A-3vkgA:
undetectable		 4em2A-3vkgA:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wh9 ENDO-BETA-1,4-MANNAN
ASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 THR A  22
LEU A  51
VAL A  53
GLN A 307
 None
 0.92A 4em2A-3wh9A:
undetectable		 4em2A-3wh9A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxm PROTEIN PELOTA
HOMOLOG

(Aeropyrum
pernix) 		PF03463
(eRF1_1)
PF03465
(eRF1_3) 		4 LEU B 120
ARG B 108
VAL B  13
VAL B 106
 None
 0.94A 4em2A-3wxmB:
undetectable		 4em2A-3wxmB:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ze7 PERIPLASMIC [NIFESE]
HYDROGENASE, LARGE
SUBUNIT,
SELENOCYSTEINE-CONTA
INING

(Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases) 		5 THR B 382
LEU B 115
ARG B 214
VAL B 213
VAL B 217
 None
 1.36A 4em2A-3ze7B:
undetectable		 4em2A-3ze7B:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh2 L-LACTATE
DEHYDROGENASE

(Plasmodium
falciparum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 THR A 277
VAL A 286
VAL A 289
GLN A 267
 None
 1.00A 4em2A-3zh2A:
undetectable		 4em2A-3zh2A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ziz GH5
ENDO-BETA-1,4-MANNAN
ASE

(Podospora
anserina) 		PF00150
(Cellulase) 		4 THR A  24
LEU A  53
VAL A  55
GLN A 309
 None
 0.90A 4em2A-3zizA:
undetectable		 4em2A-3zizA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2i PUTATIVE RIBOSOME
BIOGENESIS GTPASE
RSGA

(Salmonella
enterica) 		PF03193
(RsgA_GTPase) 		4 LEU V 231
VAL V 137
VAL V 135
GLN V 133
 None
 0.87A 4em2A-4a2iV:
undetectable		 4em2A-4a2iV:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5w COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2) 		4 TYR A1326
LEU A1346
VAL A1340
VAL A1338
 None
 1.01A 4em2A-4a5wA:
undetectable		 4em2A-4a5wA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxo FANCONI ANEMIA GROUP
M PROTEIN

(Homo sapiens) 		PF02732
(ERCC4) 		5 TYR A1918
LEU A1925
VAL A1896
VAL A1898
GLN A1868
 None
 1.41A 4em2A-4bxoA:
undetectable		 4em2A-4bxoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE

(Thermotoga
maritima) 		PF13597
(NRDD) 		4 TYR A 462
LEU A 474
VAL A 440
VAL A 443
 None
 0.98A 4em2A-4conA:
1.9		 4em2A-4conA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewt PEPTIDASE,
M20/M25/M40 FAMILY

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 TYR A 111
LEU A 119
VAL A 384
VAL A 380
 None
 0.97A 4em2A-4ewtA:
undetectable		 4em2A-4ewtA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glr ANTI-PTAU HEAVY
CHAIN

(Gallus gallus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU H  18
ARG H  38
VAL H 109
VAL H 111
 None
 1.00A 4em2A-4glrH:
undetectable		 4em2A-4glrH:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ilr CRISPR-ASSOCIATED
ENDORIBONUCLEASE
CAS6 2

(Sulfolobus
solfataricus) 		PF10040
(CRISPR_Cas6) 		4 TYR A   9
LEU A  40
VAL A  93
VAL A  97
 None
 0.98A 4em2A-4ilrA:
undetectable		 4em2A-4ilrA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6r ALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 TYR A 468
LEU A 171
VAL A 146
GLN A 245
 None
 0.93A 4em2A-4o6rA:
undetectable		 4em2A-4o6rA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4od7 THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Proteus
mirabilis) 		PF01323
(DSBA) 		4 THR A  72
VAL A 130
VAL A 134
GLN A 138
 None
 0.91A 4em2A-4od7A:
undetectable		 4em2A-4od7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ouo ANTI BLA G 1 SCFV

(Gallus gallus) 		PF07686
(V-set) 		4 LEU A 132
ARG A 152
VAL A 229
VAL A 231
 None
 0.99A 4em2A-4ouoA:
undetectable		 4em2A-4ouoA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0a E3 UBIQUITIN-PROTEIN
LIGASE RNF31

(Homo sapiens) 		PF09409
(PUB) 		4 LEU A  79
VAL A 153
VAL A 149
GLN A 145
 None
 0.88A 4em2A-4p0aA:
0.9		 4em2A-4p0aA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p48 ANTIBODY SCFV 180

(Gallus gallus) 		PF07686
(V-set) 		4 LEU A 146
ARG A 166
VAL A 248
VAL A 250
 None
 0.97A 4em2A-4p48A:
undetectable		 4em2A-4p48A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p49 ANTIBODY SCFV B8

(Gallus gallus) 		PF07686
(V-set) 		4 LEU A 138
ARG A 158
VAL A 240
VAL A 242
 None
 0.93A 4em2A-4p49A:
undetectable		 4em2A-4p49A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9t NUCLEOPORIN NUP133

(Vanderwaltozyma
polyspora) 		PF08801
(Nucleoporin_N) 		4 THR A 444
LEU A 400
VAL A 435
VAL A 433
 None
 0.97A 4em2A-4q9tA:
undetectable		 4em2A-4q9tA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qik ROQUIN-1

(Homo sapiens) 		no annotation 4 LEU A 137
VAL A 388
VAL A 392
GLN A 396
 None
 0.78A 4em2A-4qikA:
undetectable		 4em2A-4qikA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0v FE-HYDROGENASE

(Chlamydomonas
reinhardtii) 		PF02256
(Fe_hyd_SSU)
PF02906
(Fe_hyd_lg_C) 		4 THR A 330
LEU A 318
VAL A 388
VAL A 386
 None
 0.98A 4em2A-4r0vA:
undetectable		 4em2A-4r0vA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rph UDP-GALACTOPYRANOSE
MUTASE

(Mycobacterium
tuberculosis) 		no annotation 4 TRP B 225
ARG B 229
VAL B 241
VAL B 355
 None
 0.87A 4em2A-4rphB:
undetectable		 4em2A-4rphB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udn PERIPLASMIC SOLUTE
BINDING PROTEIN

(Candidatus
Liberibacter
asiaticus) 		PF01297
(ZnuA) 		4 LEU A  58
VAL A   7
VAL A  28
GLN A  19
 None
 0.92A 4em2A-4udnA:
undetectable		 4em2A-4udnA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2p KETOSYNTHASE

(Myxococcus
fulvus) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		5 THR A 320
LEU A 246
TRP A 247
VAL A 332
VAL A 318
 None
 1.27A 4em2A-4v2pA:
undetectable		 4em2A-4v2pA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcr SUPEROXIDE DISMUTASE
[CU-ZN]

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 LEU A  54
VAL A  31
VAL A  29
GLN A  22
 None
 0.93A 4em2A-4xcrA:
undetectable		 4em2A-4xcrA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b6k UNCHARACTERIZED
PROTEIN CGKR1

([Candida]
glabrata) 		PF01370
(Epimerase) 		4 THR A 111
LEU A 115
VAL A 129
VAL A 131
 None
 0.90A 4em2A-5b6kA:
undetectable		 4em2A-5b6kA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7w UPF0234 PROTEIN
XC_3703

(Xanthomonas
campestris) 		PF04461
(DUF520) 		4 LEU A  64
VAL A  94
VAL A  96
GLN A  98
 None
 0.90A 4em2A-5b7wA:
undetectable		 4em2A-5b7wA:
25.53