SIMILAR PATTERNS OF AMINO ACIDS FOR 4EJJ_D_NCTD501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE

(Trypanosoma
brucei) 		PF00162
(PGK) 		4 PHE A 167
GLY A 375
ILE A 372
PHE A 200
 None
ADP  A 421 (-3.3A)
None
None
 0.73A 4ejjD-13pkA:
0.0		 4ejjD-13pkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bf5 SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind) 		4 PHE A 581
ASN A 515
GLY A 513
ILE A 565
 None
 0.73A 4ejjD-1bf5A:
0.0		 4ejjD-1bf5A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dih DIHYDRODIPICOLINATE
REDUCTASE

(Escherichia
coli) 		PF01113
(DapB_N)
PF05173
(DapB_C) 		4 GLY A  84
THR A  80
LEU A  66
PHE A  76
 NDP  A 301 ( 3.3A)
NDP  A 301 ( 3.7A)
None
None
 0.83A 4ejjD-1dihA:
0.0		 4ejjD-1dihA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8f BENZYL ALCOHOL
DEHYDROGENASE

(Acinetobacter
calcoaceticus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A  64
THR A  41
ILE A 370
PHE A 348
 None
 0.79A 4ejjD-1f8fA:
0.0		 4ejjD-1f8fA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR

(Rhodospirillum
rubrum) 		PF13545
(HTH_Crp_2) 		4 GLY A 199
ILE A 169
LEU A 184
PHE A 143
 None
 0.82A 4ejjD-1ft9A:
0.0		 4ejjD-1ft9A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE

(Mycobacterium
tuberculosis) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ASN A 117
GLY A 115
ILE A 134
LEU A 123
 None
 0.91A 4ejjD-1hkwA:
0.0		 4ejjD-1hkwA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0h NEOPULLULANASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 PHE A 379
GLY A 451
ILE A 508
LEU A 405
 None
 0.85A 4ejjD-1j0hA:
undetectable		 4ejjD-1j0hA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jbk CLPB PROTEIN

(Escherichia
coli) 		PF00004
(AAA) 		4 GLY A 296
ILE A 323
LEU A 280
PHE A 333
 None
 0.84A 4ejjD-1jbkA:
0.0		 4ejjD-1jbkA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpf DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pseudomonas
fluorescens) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A 192
ILE A 238
LEU A 231
PHE A 215
 None
 0.66A 4ejjD-1lpfA:
0.0		 4ejjD-1lpfA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nmb N9 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 GLY N 363
THR N 323
ILE N 317
LEU N 355
 None
 0.79A 4ejjD-1nmbN:
undetectable		 4ejjD-1nmbN:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6v SUBTILISIN-LIKE
SERINE PROTEASE

(Fervidobacterium
pennivorans) 		PF00082
(Peptidase_S8) 		4 PHE A 570
GLY A 644
THR A 653
LEU A 574
 None
 0.87A 4ejjD-1r6vA:
undetectable		 4ejjD-1r6vA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz6 CYTOCHROME C
PEROXIDASE

(Marinobacter
hydrocarbonoclasticus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		4 PHE A 192
GLY A 207
ILE A 253
LEU A 299
 HEM  A 402 (-4.8A)
None
HEM  A 402 (-4.9A)
None
 0.90A 4ejjD-1rz6A:
undetectable		 4ejjD-1rz6A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ty2 PUTATIVE EXOTOXIN
(SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 GLY A 106
ILE A 162
LEU A 160
PHE A 134
 None
 0.88A 4ejjD-1ty2A:
undetectable		 4ejjD-1ty2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uv4 ARABINAN-ENDO
1,5-ALPHA-L-ARABINAS
E

(Bacillus
subtilis) 		PF04616
(Glyco_hydro_43) 		4 ASN A 128
ILE A 121
LEU A 171
PHE A 148
 EDO  A1296 ( 4.1A)
None
EDO  A1296 (-4.2A)
None
 0.86A 4ejjD-1uv4A:
undetectable		 4ejjD-1uv4A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8a SLIT PROTEIN

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 GLY A 609
ILE A 634
LEU A 650
PHE A 639
 None
 0.89A 4ejjD-1w8aA:
undetectable		 4ejjD-1w8aA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xxb ARGININE REPRESSOR

(Escherichia
coli) 		PF02863
(Arg_repressor_C) 		4 THR A 100
ILE A 108
LEU A 112
PHE A 152
 None
 0.89A 4ejjD-1xxbA:
undetectable		 4ejjD-1xxbA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvl SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
PF02865
(STAT_int) 		4 PHE A 581
ASN A 515
GLY A 513
ILE A 565
 None
 0.78A 4ejjD-1yvlA:
undetectable		 4ejjD-1yvlA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z5x ULTRASPIRACLE
PROTEIN (USP) A
HOMOLOGUE OF RXR

(Bemisia tabaci) 		PF00104
(Hormone_recep) 		4 ASN U 341
GLY U 339
ILE U 315
LEU U 311
 None
 0.86A 4ejjD-1z5xU:
undetectable		 4ejjD-1z5xU:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aja ANKYRIN REPEAT
FAMILY PROTEIN

(Legionella
pneumophila) 		no annotation 4 GLY A 236
ILE A 215
LEU A 219
PHE A 202
 None
 0.67A 4ejjD-2ajaA:
undetectable		 4ejjD-2ajaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ajr SUGAR KINASE, PFKB
FAMILY

(Thermotoga
maritima) 		PF00294
(PfkB) 		4 GLY A  42
THR A   4
LEU A  74
PHE A  85
 None
 0.91A 4ejjD-2ajrA:
undetectable		 4ejjD-2ajrA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aky ADENYLATE KINASE

(Saccharomyces
cerevisiae) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 GLY A  90
THR A  35
ILE A  72
LEU A 101
 AP5  A 301 (-4.3A)
AP5  A 301 (-3.0A)
None
None
 0.72A 4ejjD-2akyA:
undetectable		 4ejjD-2akyA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buc DIPEPTIDYL PEPTIDASE
IV

(Sus scrofa) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 PHE A  95
ASN A  75
ILE A 114
PHE A 116
 None
NAG  A1092 (-3.1A)
None
None
 0.88A 4ejjD-2bucA:
undetectable		 4ejjD-2bucA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago) 		PF01328
(Peroxidase_2) 		4 ASN A  37
GLY A  39
ILE A  48
LEU A  94
 None
 0.71A 4ejjD-2ciyA:
undetectable		 4ejjD-2ciyA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8t ARGONAUTE PROTEIN

(Aquifex
aeolicus) 		PF02171
(Piwi) 		4 PHE A  88
GLY A 302
LEU A 100
PHE A  91
 None
 0.71A 4ejjD-2f8tA:
undetectable		 4ejjD-2f8tA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ido DNA POLYMERASE III
EPSILON SUBUNIT

(Escherichia
coli) 		PF00929
(RNase_T) 		4 THR A 121
ILE A  90
LEU A  11
PHE A  86
 None
 0.84A 4ejjD-2idoA:
undetectable		 4ejjD-2idoA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE

(Escherichia
coli) 		PF01204
(Trehalase) 		4 PHE A  63
GLY A  45
ILE A  75
PHE A  98
 None
 0.89A 4ejjD-2jf4A:
undetectable		 4ejjD-2jf4A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgv TAGATOSE-6-PHOSPHATE
KINASE

(Staphylococcus
aureus) 		PF00294
(PfkB) 		4 GLY A  39
THR A   4
LEU A  71
PHE A  80
 None
 0.87A 4ejjD-2jgvA:
undetectable		 4ejjD-2jgvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nqn MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
MOEA

(Escherichia
coli) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 GLY A 251
THR A 185
LEU A 265
PHE A 237
 None
GOL  A 523 ( 4.7A)
None
None
 0.81A 4ejjD-2nqnA:
undetectable		 4ejjD-2nqnA:
22.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pg6 CYTOCHROME P450 2A6

(Homo sapiens) 		PF00067
(p450) 		6 PHE A 107
GLY A 301
THR A 305
ILE A 366
LEU A 370
PHE A 480
 None
HEM  A 500 ( 4.7A)
HEM  A 500 (-3.6A)
HEM  A 500 ( 4.1A)
HEM  A 500 ( 3.8A)
None
 0.47A 4ejjD-2pg6A:
63.8		 4ejjD-2pg6A:
99.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qc5 STREPTOGRAMIN B
LACTONASE

(Staphylococcus
cohnii) 		no annotation 4 ASN A 138
ILE A 122
LEU A 173
PHE A 156
 ASN  A 138 ( 0.6A)
ILE  A 122 ( 0.7A)
LEU  A 173 ( 0.6A)
PHE  A 156 ( 1.3A)
 0.80A 4ejjD-2qc5A:
undetectable		 4ejjD-2qc5A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qm1 GLUCOKINASE

(Enterococcus
faecalis) 		PF00480
(ROK) 		4 GLY A 248
THR A 251
ILE A 265
LEU A 276
 None
 0.73A 4ejjD-2qm1A:
undetectable		 4ejjD-2qm1A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7b BENZOATE-COENZYME A
LIGASE

(Paraburkholderia
xenovorans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A  90
GLY A 241
LEU A 189
PHE A 187
 None
 0.90A 4ejjD-2v7bA:
undetectable		 4ejjD-2v7bA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9t TUMOR PROTEIN 63

(Homo sapiens) 		PF07647
(SAM_2) 		4 GLY A 600
ILE A 576
LEU A 584
PHE A 565
 None
 0.79A 4ejjD-2y9tA:
undetectable		 4ejjD-2y9tA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yev CYTOCHROME C OXIDASE
POLYPEPTIDE I+III

(Thermus
thermophilus) 		PF00115
(COX1)
PF00510
(COX3) 		4 ASN A 356
GLY A 360
THR A 363
LEU A 435
 None
None
None
4AG  A1200 ( 4.2A)
 0.68A 4ejjD-2yevA:
undetectable		 4ejjD-2yevA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfx UPF0100 PROTEIN
MA_0280

(Methanosarcina
acetivorans) 		PF13531
(SBP_bac_11) 		4 GLY A 193
ILE A 221
LEU A 223
PHE A 155
 None
None
GOL  A 901 (-4.0A)
None
 0.70A 4ejjD-3cfxA:
undetectable		 4ejjD-3cfxA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d46 PUTATIVE GALACTONATE
DEHYDRATASE

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PHE A 389
GLY A 308
THR A 310
ILE A 112
 None
 0.81A 4ejjD-3d46A:
undetectable		 4ejjD-3d46A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Vibrio cholerae) 		PF01979
(Amidohydro_1) 		4 ASN A 356
GLY A 347
ILE A 340
LEU A 123
 None
 0.78A 4ejjD-3egjA:
undetectable		 4ejjD-3egjA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcw PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9

(Homo sapiens) 		PF00082
(Peptidase_S8) 		4 GLY A 337
THR A 339
ILE A 424
PHE A 429
 None
 0.85A 4ejjD-3gcwA:
undetectable		 4ejjD-3gcwA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm7 ALLANTOINASE

(Bacillus
halodurans) 		PF01979
(Amidohydro_1) 		4 ASN A 396
GLY A 422
LEU A 358
PHE A  56
 None
 0.75A 4ejjD-3hm7A:
undetectable		 4ejjD-3hm7A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hur ALANINE RACEMASE

(Oenococcus oeni) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PHE A  54
GLY A  42
ILE A 249
LEU A  15
 None
 0.71A 4ejjD-3hurA:
undetectable		 4ejjD-3hurA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvn HEMOLYSIN

(Streptococcus
suis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 GLY A 255
ILE A 119
LEU A 102
PHE A 242
 None
 0.83A 4ejjD-3hvnA:
undetectable		 4ejjD-3hvnA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icq EXPORTIN-T

(Schizosaccharomyces
pombe) 		PF08389
(Xpo1) 		4 PHE T 116
GLY T 155
ILE T 188
PHE T 128
 None
 0.85A 4ejjD-3icqT:
undetectable		 4ejjD-3icqT:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0s DNA MISMATCH REPAIR
PROTEIN MUTS

(Escherichia
coli) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 GLY A 142
ILE A 136
LEU A 189
PHE A 184
 None
 0.90A 4ejjD-3k0sA:
undetectable		 4ejjD-3k0sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4x PROLIFERATING CELL
NUCLEAR ANTIGEN

(Saccharomyces
cerevisiae) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 PHE A  57
GLY A 244
ILE A  15
LEU A  11
 None
 0.67A 4ejjD-3k4xA:
undetectable		 4ejjD-3k4xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4x PROLIFERATING CELL
NUCLEAR ANTIGEN

(Saccharomyces
cerevisiae) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 PHE A 324
GLY A 511
ILE A 282
LEU A 278
 None
 0.72A 4ejjD-3k4xA:
undetectable		 4ejjD-3k4xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4x PROLIFERATING CELL
NUCLEAR ANTIGEN

(Saccharomyces
cerevisiae) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 PHE A 591
GLY A 778
ILE A 549
LEU A 545
 None
 0.73A 4ejjD-3k4xA:
undetectable		 4ejjD-3k4xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ks7 PUTATIVE PUTATIVE
PNGASE F

(Bacteroides
fragilis) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 ASN A 245
GLY A 138
ILE A 118
LEU A 115
 None
 0.71A 4ejjD-3ks7A:
undetectable		 4ejjD-3ks7A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4c DEDICATOR OF
CYTOKINESIS PROTEIN
1

(Homo sapiens) 		PF14429
(DOCK-C2) 		4 PHE A 513
ILE A 604
LEU A 432
PHE A 602
 None
 0.83A 4ejjD-3l4cA:
undetectable		 4ejjD-3l4cA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6a ATP-DEPENDENT
PROTEASE LA 1

(Bacillus
subtilis) 		PF00004
(AAA)
PF05362
(Lon_C) 		4 GLY A 723
ILE A 745
LEU A 717
PHE A 755
 None
 0.88A 4ejjD-3m6aA:
undetectable		 4ejjD-3m6aA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n7k BOTULINUM NEUROTOXIN
TYPE C1

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 PHE A 938
ASN A1015
ILE A1040
PHE A1042
 None
 0.83A 4ejjD-3n7kA:
undetectable		 4ejjD-3n7kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyf D-ARGININE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF01266
(DAO) 		4 GLY A1334
ILE A1145
LEU A1150
PHE A1069
 FAD  A1500 (-3.3A)
None
None
None
 0.89A 4ejjD-3nyfA:
undetectable		 4ejjD-3nyfA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5c CYTOCHROME C551
PEROXIDASE

(Shewanella
oneidensis) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		4 PHE A 199
GLY A 214
ILE A 257
LEU A 303
 None
None
HEM  A 501 ( 4.7A)
None
 0.85A 4ejjD-3o5cA:
undetectable		 4ejjD-3o5cA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o7o ENDOGLUCANASE

(Thermotoga
maritima) 		PF01670
(Glyco_hydro_12) 		4 PHE A 224
GLY A  72
ILE A 252
LEU A 254
 None
 0.76A 4ejjD-3o7oA:
undetectable		 4ejjD-3o7oA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8l GERANYLTRANSTRANSFER
ASE

(Enterococcus
faecalis) 		PF00348
(polyprenyl_synt) 		4 GLY A 189
ILE A 271
LEU A 283
PHE A 278
 None
 0.90A 4ejjD-3p8lA:
undetectable		 4ejjD-3p8lA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pt7 HEMOGLOBIN II

(Phacoides
pectinatus) 		PF00042
(Globin) 		4 GLY A  72
ILE A 139
LEU A  86
PHE A 135
 HEM  A 500 ( 4.1A)
None
None
None
 0.85A 4ejjD-3pt7A:
undetectable		 4ejjD-3pt7A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thc BETA-GALACTOSIDASE

(Homo sapiens) 		PF01301
(Glyco_hydro_35)
PF13364
(BetaGal_dom4_5) 		4 ASN A  78
GLY A  76
ILE A 353
LEU A 297
 None
 0.63A 4ejjD-3thcA:
undetectable		 4ejjD-3thcA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr0 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09754
(PAC2) 		4 PHE A  32
GLY A 121
ILE A  19
PHE A  86
 None
 0.84A 4ejjD-3vr0A:
undetectable		 4ejjD-3vr0A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wh9 ENDO-BETA-1,4-MANNAN
ASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 GLY A 299
THR A 297
ILE A 258
LEU A 240
 None
 0.81A 4ejjD-3wh9A:
undetectable		 4ejjD-3wh9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ae5 SIGNAL TRANSDUCTION
PROTEIN TRAP

(Staphylococcus
aureus) 		no annotation 4 PHE A 129
ASN A 136
ILE A 116
PHE A 118
 None
 0.86A 4ejjD-4ae5A:
undetectable		 4ejjD-4ae5A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8c GLUCOSE-REPRESSIBLE
ALCOHOL
DEHYDROGENASE
TRANSCRIPTIONAL
EFFECTOR

(Saccharomyces
cerevisiae) 		PF03372
(Exo_endo_phos)
PF13855
(LRR_8) 		4 ASN D 367
ILE D 376
LEU D 362
PHE D 354
 None
 0.91A 4ejjD-4b8cD:
undetectable		 4ejjD-4b8cD:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkx HISTONE DEACETYLASE
1
METASTASIS-ASSOCIATE
D PROTEIN MTA1

(Homo sapiens) 		PF00249
(Myb_DNA-binding)
PF00850
(Hist_deacetyl)
PF01448
(ELM2) 		4 ASN B  44
GLY B  46
ILE A 210
LEU A 214
 None
 0.61A 4ejjD-4bkxB:
undetectable		 4ejjD-4bkxB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqq INTEGRASE

(Streptomyces
virus phiC31) 		PF00239
(Resolvase) 		4 GLY A   6
ILE A 116
LEU A 109
PHE A  94
 None
 0.77A 4ejjD-4bqqA:
undetectable		 4ejjD-4bqqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
BETA

(Methanothermobacter
marburgensis) 		PF04422
(FrhB_FdhB_N)
PF04432
(FrhB_FdhB_C) 		4 GLY C 211
THR C 218
ILE C 220
LEU C   3
 None
 0.84A 4ejjD-4ci0C:
undetectable		 4ejjD-4ci0C:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dav SUGAR FERMENTATION
STIMULATION PROTEIN
HOMOLOG

(Pyrococcus
furiosus) 		PF03749
(SfsA) 		4 GLY A 152
ILE A 171
LEU A 197
PHE A 173
 None
 0.74A 4ejjD-4davA:
undetectable		 4ejjD-4davA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4euo ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN (POLYAMINE)

(Agrobacterium
fabrum) 		PF13416
(SBP_bac_8) 		4 PHE A 156
GLY A 163
LEU A 191
PHE A 145
 None
 0.89A 4ejjD-4euoA:
undetectable		 4ejjD-4euoA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0g SERINE/THREONINE-PRO
TEIN KINASE ROCO4

(Dictyostelium
discoideum) 		PF07714
(Pkinase_Tyr) 		4 PHE A1219
GLY A1139
ILE A1160
LEU A1155
 None
 0.87A 4ejjD-4f0gA:
undetectable		 4ejjD-4f0gA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fvv NEUROTOXIN

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 PHE A 934
ASN A1011
ILE A1036
PHE A1038
 None
 0.82A 4ejjD-4fvvA:
undetectable		 4ejjD-4fvvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 GLY M 694
ILE M 595
LEU M 599
PHE M 618
 None
 0.77A 4ejjD-4gq2M:
undetectable		 4ejjD-4gq2M:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iop KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY F MEMBER 2

(Homo sapiens) 		PF00059
(Lectin_C) 		4 ASN B 127
GLY B 177
ILE B 192
PHE B  92
 None
 0.83A 4ejjD-4iopB:
undetectable		 4ejjD-4iopB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0k TANNASE

(Lactobacillus
plantarum) 		no annotation 4 ASN A  94
GLY A  96
LEU A  70
PHE A 461
 None
 0.86A 4ejjD-4j0kA:
undetectable		 4ejjD-4j0kA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jla ADENYLATE KINASE

(Aquifex
aeolicus) 		PF00406
(ADK) 		4 GLY A  82
THR A  31
ILE A  68
LEU A  93
 ADP  A 302 (-4.4A)
ADP  A 302 (-3.6A)
None
None
 0.64A 4ejjD-4jlaA:
undetectable		 4ejjD-4jlaA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 PHE A 400
GLY A 501
LEU A 486
PHE A 422
 None
 0.91A 4ejjD-4kxbA:
undetectable		 4ejjD-4kxbA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l60 PROLIFERATING CELL
NUCLEAR ANTIGEN

(Saccharomyces
cerevisiae) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 PHE A  57
GLY A 244
ILE A  15
LEU A  11
 None
 0.82A 4ejjD-4l60A:
undetectable		 4ejjD-4l60A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfw ACYL-COA
THIOESTERASE II

(Yersinia pestis) 		PF13622
(4HBT_3) 		4 PHE A  35
GLY A 200
ILE A 158
LEU A   8
 None
 0.87A 4ejjD-4qfwA:
undetectable		 4ejjD-4qfwA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4z PNGF-II

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 GLY A 265
ILE A 216
LEU A 218
PHE A 252
 None
 0.90A 4ejjD-4r4zA:
undetectable		 4ejjD-4r4zA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlq BENZOATE-COENZYME A
LIGASE

(Rhodopseudomonas
palustris) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A  80
GLY A 231
LEU A 179
PHE A 177
 None
 0.90A 4ejjD-4rlqA:
undetectable		 4ejjD-4rlqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqg DNA POLYMERASE

(Geobacillus
stearothermophilus) 		PF00476
(DNA_pol_A) 		4 GLY A 590
ILE A 626
LEU A 623
PHE A 640
 None
 0.66A 4ejjD-4uqgA:
undetectable		 4ejjD-4uqgA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xea PEPTIDASE M16 DOMAIN
PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 GLY A 262
ILE A 338
LEU A 342
PHE A 289
 None
 0.85A 4ejjD-4xeaA:
undetectable		 4ejjD-4xeaA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfq L,D-TRANSPEPTIDASE 5

(Mycobacterium
tuberculosis) 		PF03734
(YkuD) 		4 GLY A 124
ILE A  84
LEU A  98
PHE A 149
 PEG  A 502 ( 3.3A)
None
None
None
 0.91A 4ejjD-4zfqA:
undetectable		 4ejjD-4zfqA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zuz SIDC

(Legionella
pneumophila) 		no annotation 4 GLY A 147
ILE A 133
LEU A 123
PHE A  57
 None
 0.64A 4ejjD-4zuzA:
undetectable		 4ejjD-4zuzA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 2

(Homo sapiens) 		PF00043
(GST_C) 		4 PHE B 199
GLY B 184
LEU B 112
PHE B 216
 None
 0.90A 4ejjD-5a1nB:
undetectable		 4ejjD-5a1nB:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2

(Homo sapiens) 		PF01551
(Peptidase_M23) 		4 ASN A 123
GLY A  37
ILE A  15
LEU A 133
 None
 0.81A 4ejjD-5b0hA:
undetectable		 4ejjD-5b0hA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bz3 NA(+)/H(+)
ANTIPORTER

(Thermus
thermophilus) 		PF00999
(Na_H_Exchanger) 		4 GLY A 217
ILE A 261
LEU A 248
PHE A  69
 None
 0.82A 4ejjD-5bz3A:
undetectable		 4ejjD-5bz3A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csl ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
PF08326
(ACC_central) 		4 GLY A 507
ILE A 498
LEU A 475
PHE A 536
 None
 0.81A 4ejjD-5cslA:
undetectable		 4ejjD-5cslA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9w MRNA CAP GUANINE-N7
METHYLTRANSFERASE

(Homo sapiens) 		PF03291
(Pox_MCEL) 		4 PHE A 175
GLY A 454
ILE A 403
LEU A 412
 None
 0.65A 4ejjD-5e9wA:
undetectable		 4ejjD-5e9wA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fkw DNA POLYMERASE III
EPSILON

(Escherichia
coli) 		PF00929
(RNase_T) 		4 THR D 121
ILE D  90
LEU D  11
PHE D  86
 None
 0.73A 4ejjD-5fkwD:
undetectable		 4ejjD-5fkwD:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC

(Zea mays) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 PHE A 609
GLY A 553
ILE A 518
PHE A 596
 None
 0.80A 4ejjD-5h8yA:
undetectable		 4ejjD-5h8yA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwr CEREBELLIN-1

(Rattus
norvegicus) 		PF00386
(C1q) 		4 ASN A 123
GLY A 179
ILE A  84
LEU A 171
 None
 0.78A 4ejjD-5kwrA:
undetectable		 4ejjD-5kwrA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m8h ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Psychrobacter
arcticus) 		PF01634
(HisG) 		4 GLY E 121
ILE E 134
LEU E 132
PHE E 146
 None
 0.77A 4ejjD-5m8hE:
undetectable		 4ejjD-5m8hE:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opi TAP BINDING
PROTEIN-LIKE VARIANT

(Homo sapiens) 		no annotation 4 PHE C 124
ILE C  75
LEU C  23
PHE C  77
 None
 0.88A 4ejjD-5opiC:
undetectable		 4ejjD-5opiC:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf2 PROLACTIN REGULATORY
ELEMENT-BINDING
PROTEIN

(Homo sapiens) 		PF00400
(WD40) 		4 GLY A  26
ILE A  29
LEU A  77
PHE A  95
 None
 0.89A 4ejjD-5tf2A:
undetectable		 4ejjD-5tf2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr3 DIHYDROLIPOYL
DEHYDROGENASE

(Pseudomonas
putida) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A 193
ILE A 239
LEU A 232
PHE A 216
 None
 0.72A 4ejjD-5tr3A:
undetectable		 4ejjD-5tr3A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xap PROTEIN TRANSLOCASE
SUBUNIT SECD

(Deinococcus
radiodurans) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 GLY A 355
THR A 359
ILE A 337
LEU A 341
 None
None
OLC  A 807 (-4.5A)
None
 0.88A 4ejjD-5xapA:
undetectable		 4ejjD-5xapA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 ASN A 318
THR A 327
LEU A 313
PHE A 304
 None
 0.84A 4ejjD-5y3jA:
undetectable		 4ejjD-5y3jA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zh5 LYSINE--TRNA LIGASE

(Plasmodium
falciparum) 		no annotation 4 PHE A 364
GLY A 554
ILE A 325
LEU A 265
 None
LYS  A 601 ( 3.8A)
None
None
 0.86A 4ejjD-5zh5A:
undetectable		 4ejjD-5zh5A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6at7 PHENYLALANINE
AMMONIA-LYASE

(Sorghum bicolor) 		no annotation 4 PHE A 102
ASN A 247
GLY A 242
LEU A 124
 None
MDO  A 190 ( 3.2A)
None
None
 0.81A 4ejjD-6at7A:
undetectable		 4ejjD-6at7A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bz0 DIHYDROLIPOYL
DEHYDROGENASE

(Acinetobacter
baumannii) 		no annotation 4 GLY A 192
ILE A 238
LEU A 231
PHE A 215
 None
 0.75A 4ejjD-6bz0A:
undetectable		 4ejjD-6bz0A:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cp0 -

(-) 		no annotation 4 GLY A 144
ILE A 130
LEU A 120
PHE A  55
 None
 0.66A 4ejjD-6cp0A:
undetectable		 4ejjD-6cp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6deg BETA SLIDING CLAMP

(Bartonella
birtlesii) 		no annotation 4 PHE A 345
GLY A 325
LEU A 297
PHE A 270
 None
 0.82A 4ejjD-6degA:
undetectable		 4ejjD-6degA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5z 24-STEROL
C-METHYLTRANSFERASE
UPF0434 FAMILY
PROTEIN

(Haloferax
volcanii) 		no annotation 4 GLY A  65
THR A  41
ILE C   8
LEU C   9
 None
None
None
GOL  C 101 ( 4.7A)
 0.88A 4ejjD-6f5zA:
undetectable		 4ejjD-6f5zA:
10.36