SIMILAR PATTERNS OF AMINO ACIDS FOR 4EJG_A_NCTA501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 PHE A1098
PHE A1139
ALA A1136
THR A1223
 None
 1.01A 4ejgA-1foeA:
0.0		 4ejgA-1foeA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fvf SEC1

(Doryteuthis
pealeii) 		PF00995
(Sec1) 		4 ASN A 195
PHE A 198
ALA A 199
LEU A 228
 None
 0.78A 4ejgA-1fvfA:
0.0		 4ejgA-1fvfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmk SURFACTIN SYNTHETASE

(Bacillus
subtilis) 		PF00975
(Thioesterase) 		4 PHE C  49
PHE C  24
ALA C  62
LEU C  76
 None
 1.07A 4ejgA-1jmkC:
0.0		 4ejgA-1jmkC:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m33 BIOH PROTEIN

(Escherichia
coli) 		PF00561
(Abhydrolase_1) 		4 PHE A 238
PHE A 245
ALA A 106
LEU A  79
 None
 0.99A 4ejgA-1m33A:
0.0		 4ejgA-1m33A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpy CATECHOL
2,3-DIOXYGENASE

(Pseudomonas
putida) 		PF00903
(Glyoxalase) 		4 PHE A 117
PHE A 109
PHE A  70
LEU A 167
 None
 1.06A 4ejgA-1mpyA:
0.1		 4ejgA-1mpyA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ois DNA TOPOISOMERASE I

(Saccharomyces
cerevisiae) 		PF02919
(Topoisom_I_N) 		4 PHE A 241
PHE A 187
ALA A 185
LEU A 162
 None
 0.97A 4ejgA-1oisA:
undetectable		 4ejgA-1oisA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 PHE A 740
PHE A 744
ALA A 672
LEU A 706
 None
 1.01A 4ejgA-1qvrA:
0.0		 4ejgA-1qvrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rtg HUMAN GELATINASE A

(Homo sapiens) 		PF00045
(Hemopexin) 		4 PHE A 583
ALA A 571
THR A 580
LEU A 561
 None
 1.10A 4ejgA-1rtgA:
undetectable		 4ejgA-1rtgA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3i PROBABLE CYSTEINE
DESULFURASE

(Synechocystis
sp.) 		PF00266
(Aminotran_5) 		4 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.06A 4ejgA-1t3iA:
0.0		 4ejgA-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yix DEOXYRIBONUCLEASE
YCFH

(Escherichia
coli) 		PF01026
(TatD_DNase) 		4 PHE A  36
PHE A   2
PHE A 250
ALA A 251
 None
 0.91A 4ejgA-1yixA:
undetectable		 4ejgA-1yixA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytq BETA CRYSTALLIN B2

(Homo sapiens) 		PF00030
(Crystall) 		4 PHE A  71
PHE A  73
ALA A  48
LEU A  96
 None
 0.92A 4ejgA-1ytqA:
undetectable		 4ejgA-1ytqA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw1 PROTEIN YTNJ

(Bacillus
subtilis) 		PF00296
(Bac_luciferase) 		4 PHE A 386
PHE A   9
PHE A 363
LEU A 407
 None
 0.99A 4ejgA-1yw1A:
undetectable		 4ejgA-1yw1A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3o PYRUVATE-FERREDOXIN
OXIDOREDUCTASE

(Desulfovibrio
africanus) 		PF01558
(POR)
PF01855
(POR_N)
PF02775
(TPP_enzyme_C)
PF10371
(EKR)
PF13484
(Fer4_16)
PF17147
(PFOR_II) 		4 PHE A 313
PHE A 308
PHE A 348
LEU A 340
 None
 0.95A 4ejgA-2c3oA:
undetectable		 4ejgA-2c3oA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4t 5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE

(Streptomyces
cattleya) 		PF01887
(SAM_adeno_trans) 		4 ASN A 123
ALA A 121
THR A  74
LEU A 131
 None
 0.97A 4ejgA-2c4tA:
undetectable		 4ejgA-2c4tA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2it4 CARBONIC ANHYDRASE 1

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 PHE A  93
ASN A  69
PHE A 176
LEU A  90
 None
 0.96A 4ejgA-2it4A:
undetectable		 4ejgA-2it4A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kd7 PUTATIVE CHITOBIASE

(Bacteroides
thetaiotaomicron) 		PF00754
(F5_F8_type_C) 		4 PHE A 105
ASN A 134
ALA A 138
LEU A 126
 None
 0.94A 4ejgA-2kd7A:
undetectable		 4ejgA-2kd7A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mjw PROTEIN S100-P

(Homo sapiens) 		PF01023
(S_100) 		4 PHE B  74
PHE B  71
ALA B  79
THR B  82
 None
 1.10A 4ejgA-2mjwB:
undetectable		 4ejgA-2mjwB:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nra PI PROTEIN

(Escherichia
coli) 		PF01051
(Rep_3) 		4 PHE C 246
PHE C 261
ALA C 231
LEU C 198
 None
 0.63A 4ejgA-2nraC:
undetectable		 4ejgA-2nraC:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwu UPF0201 PROTEIN
SSO1042

(Sulfolobus
solfataricus) 		PF01877
(RNA_binding) 		4 PHE A  84
PHE A  98
ALA A 127
LEU A  96
 None
 1.08A 4ejgA-2nwuA:
undetectable		 4ejgA-2nwuA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pe4 HYALURONIDASE-1

(Homo sapiens) 		PF01630
(Glyco_hydro_56) 		4 PHE A 290
ALA A  38
THR A  40
LEU A 344
 None
 0.92A 4ejgA-2pe4A:
undetectable		 4ejgA-2pe4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prr ALKYLHYDROPEROXIDASE
AHPD CORE:
UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF02627
(CMD) 		4 PHE A 129
ALA A 130
THR A 165
LEU A  68
 None
 0.97A 4ejgA-2prrA:
undetectable		 4ejgA-2prrA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r1f PREDICTED
AMINODEOXYCHORISMATE
LYASE

(Escherichia
coli) 		PF02618
(YceG) 		4 PHE A 306
PHE A 316
PHE A 232
ALA A 229
 GOL  A 350 (-3.8A)
None
GOL  A 350 (-4.8A)
None
 0.84A 4ejgA-2r1fA:
undetectable		 4ejgA-2r1fA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt4 MCBG-LIKE PROTEIN

(Xanthomonas
albilineans) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		4 PHE A  31
PHE A  51
PHE A  16
LEU A  46
 None
 1.10A 4ejgA-2xt4A:
undetectable		 4ejgA-2xt4A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		4 PHE A 273
PHE A 265
PHE A 119
LEU A 107
 None
EDO  A 535 (-4.7A)
None
None
 1.03A 4ejgA-2yeqA:
undetectable		 4ejgA-2yeqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1k (NEO)PULLULANASE

(Thermus
thermophilus) 		PF00128
(Alpha-amylase) 		4 PHE A 338
ALA A 335
THR A 380
LEU A 319
 None
 0.87A 4ejgA-2z1kA:
undetectable		 4ejgA-2z1kA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 PHE B 376
PHE B 380
PHE B 397
THR B 353
 None
None
None
G  E  53 ( 4.1A)
 0.87A 4ejgA-3al0B:
undetectable		 4ejgA-3al0B:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE

(Homo sapiens) 		PF16113
(ECH_2) 		4 PHE A 194
PHE A 272
PHE A 291
ALA A 292
 None
 0.91A 4ejgA-3bptA:
undetectable		 4ejgA-3bptA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e4e CYTOCHROME P450 2E1

(Homo sapiens) 		PF00067
(p450) 		4 PHE A 106
PHE A 116
ALA A 299
THR A 303
 None
None
HEM  A 500 ( 3.3A)
4PZ  A 501 ( 2.8A)
 0.92A 4ejgA-3e4eA:
52.3		 4ejgA-3e4eA:
51.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efx CHOLERA ENTEROTOXIN
SUBUNIT B,
HEAT-LABILE
ENTEROTOXIN B CHAIN

(Escherichia
coli;
Vibrio cholerae) 		PF01376
(Enterotoxin_b) 		4 PHE D  42
ALA D  75
THR D  71
LEU D  85
 None
 1.07A 4ejgA-3efxD:
undetectable		 4ejgA-3efxD:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euw MYO-INOSITOL
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 PHE A 182
PHE A 183
ALA A 131
LEU A 239
 None
 1.09A 4ejgA-3euwA:
undetectable		 4ejgA-3euwA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewb 2-ISOPROPYLMALATE
SYNTHASE

(Listeria
monocytogenes) 		PF00682
(HMGL-like) 		4 PHE X 265
ASN X 229
ALA X 239
THR X 210
 None
 0.89A 4ejgA-3ewbX:
undetectable		 4ejgA-3ewbX:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g3z TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Neisseria
meningitidis) 		PF01047
(MarR) 		4 PHE A  18
PHE A  32
ALA A  33
THR A  37
 None
 0.74A 4ejgA-3g3zA:
undetectable		 4ejgA-3g3zA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is6 PUTATIVE PERMEASE
PROTEIN, ABC
TRANSPORTER

(Porphyromonas
gingivalis) 		PF12704
(MacB_PCD) 		4 PHE A 187
ALA A 124
THR A 101
LEU A 190
 None
 1.00A 4ejgA-3is6A:
undetectable		 4ejgA-3is6A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq3 LOMBRICINE KINASE

(Urechis caupo) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 PHE A 295
ALA A 316
THR A 309
LEU A 286
 None
 1.09A 4ejgA-3jq3A:
undetectable		 4ejgA-3jq3A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr3 NAD-DEPENDENT
DEACETYLASE

(Thermotoga
maritima) 		PF02146
(SIR2) 		4 PHE A  48
PHE A 161
PHE A  63
ALA A  64
 None
 1.06A 4ejgA-3jr3A:
undetectable		 4ejgA-3jr3A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		4 ASN A 561
PHE A 564
ALA A 524
THR A 527
 THH  A 642 ( 3.3A)
None
None
None
 0.91A 4ejgA-3k13A:
undetectable		 4ejgA-3k13A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzp PUTATIVE DIGUANYLATE
CYCLASE/PHOSPHODIEST
ERASE

(Listeria
monocytogenes) 		PF00563
(EAL) 		4 PHE A  55
ALA A  80
THR A 108
LEU A  28
 None
None
None
CL  A 237 (-4.4A)
 0.83A 4ejgA-3kzpA:
undetectable		 4ejgA-3kzpA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2n PEPTIDASE M14,
CARBOXYPEPTIDASE A

(Shewanella
denitrificans) 		PF00246
(Peptidase_M14) 		4 PHE A 300
PHE A 359
ALA A 366
LEU A 334
 None
 0.95A 4ejgA-3l2nA:
undetectable		 4ejgA-3l2nA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m9u FARNESYL-DIPHOSPHATE
SYNTHASE

(Lactobacillus
brevis) 		PF00348
(polyprenyl_synt) 		4 PHE A 216
PHE A 212
ALA A 191
LEU A 287
 None
 1.09A 4ejgA-3m9uA:
undetectable		 4ejgA-3m9uA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odg XANTHOSINE
PHOSPHORYLASE

(Yersinia
pseudotuberculosis) 		PF01048
(PNP_UDP_1) 		4 PHE A 121
PHE A  38
PHE A 273
LEU A 281
 None
 1.07A 4ejgA-3odgA:
undetectable		 4ejgA-3odgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogr BETA-GALACTOSIDASE

(Trichoderma
reesei) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ASN A 331
ALA A 333
THR A 417
LEU A 277
 None
 0.92A 4ejgA-3ogrA:
undetectable		 4ejgA-3ogrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pss QNR

(Aeromonas
hydrophila) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		4 PHE A  22
PHE A  42
PHE A   7
LEU A  37
 None
None
MLY  A   5 ( 4.4A)
None
 1.04A 4ejgA-3pssA:
undetectable		 4ejgA-3pssA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pss QNR

(Aeromonas
hydrophila) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		4 PHE A  42
PHE A  68
PHE A  27
LEU A  63
 None
 1.00A 4ejgA-3pssA:
undetectable		 4ejgA-3pssA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw3 OROTIDINE-5-PHOSPHAT
E
DECARBOXYLASE/OROTAT
E
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE
(OMPDCASE-OPRTASE,
PUTATIVE)

(Leishmania
infantum) 		PF00215
(OMPdecase) 		4 PHE A 131
ASN A 171
PHE A   3
LEU A 194
 None
 0.94A 4ejgA-3qw3A:
undetectable		 4ejgA-3qw3A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s88 ENVELOPE
GLYCOPROTEIN

(Sudan
ebolavirus) 		PF01611
(Filo_glycop) 		4 PHE I 160
PHE I 176
ALA I  82
LEU I 111
 None
 0.88A 4ejgA-3s88I:
undetectable		 4ejgA-3s88I:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN

(Bacteroides
fragilis) 		PF14254
(DUF4348) 		4 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
 0.79A 4ejgA-3sbuA:
undetectable		 4ejgA-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbu HYPOTHETICAL
NTF2-LIKE PROTEIN

(Bacteroides
fragilis) 		PF14254
(DUF4348) 		4 PHE A 267
PHE A 177
PHE A 184
ALA A 185
 None
 0.70A 4ejgA-3sbuA:
undetectable		 4ejgA-3sbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3voh CELLOBIOHYDROLASE

(Coprinopsis
cinerea) 		PF01341
(Glyco_hydro_6) 		4 PHE A 422
PHE A 362
ALA A 429
LEU A 108
 None
 1.01A 4ejgA-3vohA:
undetectable		 4ejgA-3vohA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arx PESTICIDAL CRYSTAL
PROTEIN CRY1AC

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 PHE A 462
PHE A 328
ASN A 301
ALA A 352
 None
 1.09A 4ejgA-4arxA:
1.6		 4ejgA-4arxA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8a GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF16415
(CNOT1_CAF1_bind) 		4 PHE A 934
PHE A 915
ALA A 914
LEU A 774
 None
 0.74A 4ejgA-4b8aA:
undetectable		 4ejgA-4b8aA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		4 PHE B2666
PHE B2662
ALA B2709
LEU B2654
 None
 1.05A 4ejgA-4bedB:
undetectable		 4ejgA-4bedB:
14.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv4 PROTEIN TOLL,
VARIABLE LYMPHOCYTE
RECEPTOR B CHIMERA

(Drosophila
melanogaster;
Eptatretus
burgeri) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 PHE R 155
ALA R 183
THR R 163
LEU R 169
 None
 1.08A 4ejgA-4bv4R:
undetectable		 4ejgA-4bv4R:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by9 NOP5/NOP56 RELATED
PROTEIN

(Pyrococcus
furiosus) 		PF01798
(Nop) 		4 PHE C  59
PHE C  61
ALA C  11
LEU C  44
 None
 1.03A 4ejgA-4by9C:
undetectable		 4ejgA-4by9C:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cso ORFY PROTEIN,
TRANSCRIPTION FACTOR

(Thermoproteus
tenax) 		no annotation 4 PHE A  68
PHE A 120
ALA A  28
LEU A 107
 None
 1.03A 4ejgA-4csoA:
undetectable		 4ejgA-4csoA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eay MANNONATE
DEHYDRATASE

(Escherichia
coli) 		PF03786
(UxuA) 		4 ASN A 211
PHE A 212
ALA A 213
THR A 260
 None
 1.04A 4ejgA-4eayA:
undetectable		 4ejgA-4eayA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd2 CHAPERONE PROTEIN
CLPB

(Thermus
thermophilus) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 PHE A 740
PHE A 744
ALA A 672
LEU A 706
 None
 1.04A 4ejgA-4fd2A:
undetectable		 4ejgA-4fd2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gi5 QUINONE REDUCTASE

(Klebsiella
pneumoniae) 		PF02525
(Flavodoxin_2) 		4 PHE A 194
PHE A  22
ALA A  23
LEU A 192
 None
 0.83A 4ejgA-4gi5A:
undetectable		 4ejgA-4gi5A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyn CHEC, INHIBITOR OF
MCP METHYLATION /
FLIN FUSION PROTEIN

(Thermotoga
maritima) 		PF04509
(CheC) 		4 PHE A 188
PHE A 200
ALA A  44
LEU A  96
 None
 0.94A 4ejgA-4hynA:
undetectable		 4ejgA-4hynA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5u CHIMERIC CEL6A

(Chaetomium
thermophilum;
Humicola
insolens;
Trichoderma
reesei) 		PF01341
(Glyco_hydro_6) 		4 PHE A 435
PHE A 375
ALA A 442
LEU A 121
 None
 1.05A 4ejgA-4i5uA:
undetectable		 4ejgA-4i5uA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifq NUCLEOPORIN NUP192

(Saccharomyces
cerevisiae) 		PF11894
(Nup192) 		4 PHE A 713
PHE A 709
PHE A 753
LEU A 675
 None
 1.05A 4ejgA-4ifqA:
undetectable		 4ejgA-4ifqA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB
YENC2

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
no annotation 		4 PHE A1097
ALA A1113
THR B  95
LEU A1089
 None
 0.92A 4ejgA-4iglA:
undetectable		 4ejgA-4iglA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iiw LMO1499 PROTEIN

(Listeria
monocytogenes) 		PF02618
(YceG) 		4 PHE A 326
PHE A 337
PHE A 253
ALA A 250
 None
 0.93A 4ejgA-4iiwA:
undetectable		 4ejgA-4iiwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2a HALOALKANE
DEHALOGENASE

(Bradyrhizobium
elkanii) 		PF00561
(Abhydrolase_1) 		4 PHE A 128
PHE A 125
ALA A 255
LEU A 228
 None
 1.06A 4ejgA-4k2aA:
undetectable		 4ejgA-4k2aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kgb SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE

(Drosophila
melanogaster) 		PF01144
(CoA_trans) 		4 PHE A 201
PHE A 203
ALA A  45
LEU A  71
 None
 1.03A 4ejgA-4kgbA:
undetectable		 4ejgA-4kgbA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgv GLUCOSE-6-PHOSPHATE
1-DEHYDROGENASE

(Mycobacterium
avium) 		PF00479
(G6PD_N)
PF02781
(G6PD_C) 		4 ASN A 256
ALA A 415
THR A 419
LEU A 174
 None
 1.09A 4ejgA-4lgvA:
undetectable		 4ejgA-4lgvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp7 MATRIX PROTEIN M

(Human
metapneumovirus) 		PF03393
(Pneumo_matrix) 		4 PHE A  39
ALA A  76
THR A  54
LEU A  48
 None
 0.84A 4ejgA-4lp7A:
undetectable		 4ejgA-4lp7A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mag SIALIC ACID BINDING
PROTEIN

(Vibrio cholerae) 		PF03480
(DctP) 		4 ASN A 201
ALA A 203
THR A 205
LEU A 142
 None
 0.91A 4ejgA-4magA:
undetectable		 4ejgA-4magA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mjf HYPOTHETICAL PROTEIN

(Bacteroides
vulgatus) 		PF14254
(DUF4348) 		4 PHE A 152
PHE A  64
PHE A  71
ALA A  72
 None
CXS  A 300 ( 4.9A)
None
EDO  A 307 ( 3.9A)
 0.67A 4ejgA-4mjfA:
undetectable		 4ejgA-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mjf HYPOTHETICAL PROTEIN

(Bacteroides
vulgatus) 		PF14254
(DUF4348) 		4 PHE A 269
PHE A 179
PHE A 186
ALA A 187
 None
 0.79A 4ejgA-4mjfA:
undetectable		 4ejgA-4mjfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7w TRANSPORTER,
SODIUM/BILE ACID
SYMPORTER FAMILY

(Yersinia
frederiksenii) 		PF01758
(SBF) 		4 PHE A 241
PHE A 243
ALA A  65
LEU A 251
 None
 1.03A 4ejgA-4n7wA:
undetectable		 4ejgA-4n7wA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nmw PIMELYL-[ACYL-CARRIE
R PROTEIN] METHYL
ESTER ESTERASE

(Salmonella
enterica) 		PF00561
(Abhydrolase_1) 		4 PHE A 238
PHE A 245
ALA A 106
LEU A  79
 None
 1.05A 4ejgA-4nmwA:
undetectable		 4ejgA-4nmwA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oet PUTATIVE PEPTIDE
ABC-TRANSPORT SYSTEM
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Campylobacter
jejuni) 		PF00496
(SBP_bac_5) 		4 PHE A 398
PHE A 444
PHE A 454
LEU A 287
 None
 1.10A 4ejgA-4oetA:
undetectable		 4ejgA-4oetA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rye D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Mycobacterium
tuberculosis) 		PF00768
(Peptidase_S11) 		4 PHE A 184
PHE A 193
ALA A 194
LEU A  50
 None
 1.06A 4ejgA-4ryeA:
undetectable		 4ejgA-4ryeA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twe N-ACETYLATED-ALPHA-L
INKED ACIDIC
DIPEPTIDASE-LIKE
PROTEIN

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 PHE A 693
PHE A 666
ALA A 726
LEU A 621
 None
 0.83A 4ejgA-4tweA:
undetectable		 4ejgA-4tweA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BONTOXILYSIN A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 PHE A1050
ASN A 854
PHE A1047
LEU A1062
 None
 1.09A 4ejgA-4zktA:
0.8		 4ejgA-4zktA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 2

(Homo sapiens) 		PF00043
(GST_C) 		4 PHE B 169
ALA B 126
THR B 195
LEU B 136
 None
 1.08A 4ejgA-5a1nB:
undetectable		 4ejgA-5a1nB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 2

(Homo sapiens) 		PF00043
(GST_C) 		4 PHE B 185
PHE B 169
THR B 195
LEU B 136
 None
 1.09A 4ejgA-5a1nB:
undetectable		 4ejgA-5a1nB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c98 AGAP007691-PB

(Anopheles
gambiae) 		PF00079
(Serpin) 		4 PHE A 381
PHE A 363
PHE A 206
LEU A 287
 None
 1.04A 4ejgA-5c98A:
undetectable		 4ejgA-5c98A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cvo UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 46

(Homo sapiens) 		PF00443
(UCH) 		4 PHE B  84
PHE B  55
ALA B  52
THR B 316
 None
 1.08A 4ejgA-5cvoB:
undetectable		 4ejgA-5cvoB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dnw SHKAI2IB

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 PHE A  91
PHE A 112
ALA A  74
LEU A  81
 None
 0.83A 4ejgA-5dnwA:
undetectable		 4ejgA-5dnwA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyg INOSITOL
MONOPHOSPHATASE

(Staphylococcus
aureus) 		PF00459
(Inositol_P) 		4 PHE A  57
PHE A  54
PHE A  62
LEU A 107
 None
 0.95A 4ejgA-5eygA:
undetectable		 4ejgA-5eygA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fx8 LINOLEATE
11-LIPOXYGENASE

(Gaeumannomyces
avenae) 		PF00305
(Lipoxygenase) 		4 PHE A 238
PHE A 247
PHE A 164
LEU A 169
 None
 1.09A 4ejgA-5fx8A:
undetectable		 4ejgA-5fx8A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gly GLYCOSIDE HYDROLASE
FAMILY 45 PROTEIN

(Thielavia
terrestris) 		PF02015
(Glyco_hydro_45) 		4 PHE A 140
ALA A  58
THR A  61
LEU A 143
 None
 1.08A 4ejgA-5glyA:
undetectable		 4ejgA-5glyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC

(Zea mays) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 PHE A 596
PHE A 522
PHE A 609
LEU A 487
 None
 1.02A 4ejgA-5h8yA:
undetectable		 4ejgA-5h8yA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hj3 ENVELOPE
GLYCOPROTEIN

(Ebola virus sp.) 		PF01611
(Filo_glycop) 		4 PHE C 160
PHE C 176
ALA C  82
LEU C 111
 None
 0.86A 4ejgA-5hj3C:
undetectable		 4ejgA-5hj3C:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmz FLUORINASE

(Streptomyces
sp. MA37) 		PF01887
(SAM_adeno_trans) 		4 ASN A 123
ALA A 121
THR A  74
LEU A 131
 None
 1.00A 4ejgA-5lmzA:
undetectable		 4ejgA-5lmzA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdx PHOTOSYSTEM II CP43
REACTION CENTER
PROTEIN

(Arabidopsis
thaliana) 		PF00421
(PSII) 		4 PHE C 315
PHE C 351
ALA C 363
LEU C 375
 None
 0.97A 4ejgA-5mdxC:
undetectable		 4ejgA-5mdxC:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndx GLYCOSYL HYDROLASE

(Rhizobium
leguminosarum) 		no annotation 4 PHE A 316
ALA A 315
THR A  25
LEU A  33
 None
 1.10A 4ejgA-5ndxA:
undetectable		 4ejgA-5ndxA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN-CONTAINING
FORMYLMETHANOFURAN
DEHYDROGENASE 2
SUBUNIT C

(Methanothermobacter
wolfeii) 		PF01493
(GXGXG) 		4 PHE C  26
ALA C  18
THR C  76
LEU C   6
 None
 1.04A 4ejgA-5t5iC:
undetectable		 4ejgA-5t5iC:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucy TUBULIN ALPHA CHAIN

(Tetrahymena
thermophila) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 PHE A 351
ASN A 329
ALA A 333
THR A 337
 None
 1.07A 4ejgA-5ucyA:
undetectable		 4ejgA-5ucyA:
21.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 PHE A 115
PHE A 297
ALA A 298
THR A 302
 9ZJ  A 502 (-4.7A)
9ZJ  A 502 ( 4.5A)
9ZJ  A 502 ( 3.5A)
9ZJ  A 502 ( 3.9A)
 0.41A 4ejgA-5wbgA:
56.5		 4ejgA-5wbgA:
65.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xcy GLUCANASE

(Phanerochaete
chrysosporium) 		PF01341
(Glyco_hydro_6) 		4 PHE A 428
PHE A 368
ALA A 435
LEU A 114
 None
 1.04A 4ejgA-5xcyA:
undetectable		 4ejgA-5xcyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E

(Mus musculus) 		no annotation 4 PHE A1188
ASN A1169
ALA A1195
THR A1223
 None
 1.01A 4ejgA-5yudA:
undetectable		 4ejgA-5yudA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxg PILUS ASSEMBLY
PROTEIN

(Lactobacillus
rhamnosus) 		no annotation 4 PHE A 274
ALA A 253
THR A 322
LEU A 265
 SME  A 275 ( 3.7A)
None
None
None
 0.96A 4ejgA-5yxgA:
undetectable		 4ejgA-5yxgA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z24 PILUS ASSEMBLY
PROTEIN

(Lactobacillus
rhamnosus) 		no annotation 4 PHE A 274
ALA A 253
THR A 322
LEU A 265
 None
 0.81A 4ejgA-5z24A:
undetectable		 4ejgA-5z24A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5za2 BETA-LACTAMASE

(Escherichia
coli) 		no annotation 4 PHE A  83
ALA A 107
THR A 111
LEU A 253
 None
 1.06A 4ejgA-5za2A:
undetectable		 4ejgA-5za2A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bxa TOLL-LIKE RECEPTOR
5B, VARIABLE
LYMPHOCYTE RECEPTOR
B CHIMERA

(Danio rerio;
Eptatretus
burgeri) 		no annotation 4 PHE A 249
PHE A 250
PHE A 226
LEU A 263
 None
 1.01A 4ejgA-6bxaA:
undetectable		 4ejgA-6bxaA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG

(Homo sapiens) 		no annotation 4 PHE A 186
PHE A 205
ALA A 207
LEU A 225
 None
 1.04A 4ejgA-6ccuA:
undetectable		 4ejgA-6ccuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5u ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1

(Zaire
ebolavirus) 		no annotation 4 PHE A 160
PHE A 176
ALA A  82
LEU A 111
 None
 0.97A 4ejgA-6f5uA:
undetectable		 4ejgA-6f5uA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f6s ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1

(Zaire
ebolavirus) 		no annotation 4 PHE A 160
PHE A 176
ALA A  82
LEU A 111
 None
None
GOL  A 506 ( 4.7A)
None
 0.98A 4ejgA-6f6sA:
undetectable		 4ejgA-6f6sA:
12.25