SIMILAR PATTERNS OF AMINO ACIDS FOR 4EAT_A_BEZA1000_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b3b | PROTEIN (GLUTAMATEDEHYDROGENASE) (Thermotogamaritima) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ALA A 238ILE A 246GLY A 245ILE A 276 | None | 0.66A | 4eatA-1b3bA:3.2 | 4eatA-1b3bA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bqc | PROTEIN(BETA-MANNANASE) (Thermobifidafusca) |
PF00150(Cellulase) | 4 | ALA A 295GLY A 250ILE A 252GLY A 23 | None | 0.57A | 4eatA-1bqcA:undetectable | 4eatA-1bqcA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1do5 | HUMAN COPPERCHAPERONE FORSUPEROXIDE DISMUTASEDOMAIN II (Homo sapiens) |
PF00080(Sod_Cu) | 5 | ALA A 91ALA A 226GLY A 94GLY A 101ILE A 119 | None | 1.17A | 4eatA-1do5A:undetectable | 4eatA-1do5A:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASESMALL SUBUNIT (Desulfovibriodesulfuricans) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ALA A 122GLY A 76ILE A 133GLY A 132 | NoneFSX A 269 ( 4.1A)NoneNone | 0.66A | 4eatA-1e3dA:undetectable | 4eatA-1e3dA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6w | SHORT CHAIN3-HYDROXYACYL-COADEHYDROGENASE (Rattusnorvegicus) |
PF00106(adh_short) | 4 | ALA A 92GLY A 21GLY A 18ILE A 15 | NAD A 301 (-3.6A)NAD A 301 (-3.2A)NoneNone | 0.67A | 4eatA-1e6wA:3.5 | 4eatA-1e6wA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1euz | GLUTAMATEDEHYDROGENASE (Thermococcusprofundus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ALA A 241ILE A 249GLY A 248ILE A 279 | None | 0.55A | 4eatA-1euzA:4.2 | 4eatA-1euzA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8w | LEUCOAGGLUTINATINGPHYTOHEMAGGLUTININ (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 4 | ALA A 89ALA A 176GLY A 139ILE A 138 | None | 0.68A | 4eatA-1g8wA:undetectable | 4eatA-1g8wA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gtm | GLUTAMATEDEHYDROGENASE (Pyrococcusfuriosus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ALA A 241ILE A 249GLY A 248ILE A 279 | None | 0.59A | 4eatA-1gtmA:2.8 | 4eatA-1gtmA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfe | PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(LARGER SUBUNIT))PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(SMALLER SUBUNIT)) (Desulfovibriovulgaris;Desulfovibriovulgaris) |
PF02906(Fe_hyd_lg_C)PF13237(Fer4_10)PF02256(Fe_hyd_SSU) | 4 | ALA L 113TYR L 112GLY S 49ILE S 47 | None | 0.64A | 4eatA-1hfeL:2.1 | 4eatA-1hfeL:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1in8 | HOLLIDAY JUNCTIONDNA HELICASE RUVB (Thermotogamaritima) |
PF05491(RuvB_C)PF05496(RuvB_N) | 4 | GLY A 313ILE A 315GLY A 275ILE A 268 | None | 0.62A | 4eatA-1in8A:2.9 | 4eatA-1in8A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itz | TRANSKETOLASE (Zea mays) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | ALA A 466GLY A 427GLY A 432ILE A 433 | None | 0.63A | 4eatA-1itzA:2.1 | 4eatA-1itzA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iy8 | LEVODIONE REDUCTASE (Leifsoniaaquatica) |
PF13561(adh_short_C2) | 4 | ALA A 100GLY A 24GLY A 21ILE A 18 | NAD A1268 ( 3.7A)NAD A1268 (-3.3A)NoneNone | 0.65A | 4eatA-1iy8A:3.7 | 4eatA-1iy8A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khd | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Pectobacteriumcarotovorum) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | ALA A 68GLY A 67ILE A 65ILE A 186 | None | 0.67A | 4eatA-1khdA:undetectable | 4eatA-1khdA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kk0 | EIF2GAMMA (Pyrococcusabyssi) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 4 | ALA A 185GLY A 184ILE A 179ILE A 147 | None | 0.68A | 4eatA-1kk0A:2.8 | 4eatA-1kk0A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ph5 | TELOMERE-BINDINGPROTEIN ALPHASUBUNIT (Sterkiella nova) |
PF02765(POT1) | 5 | ALA A 306ALA A 116GLY A 117ILE A 59ILE A 206 | None | 1.48A | 4eatA-1ph5A:undetectable | 4eatA-1ph5A:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qh5 | PROTEIN(HYDROXYACYLGLUTATHIONE HYDROLASE) (Homo sapiens) |
PF00753(Lactamase_B)PF16123(HAGH_C) | 4 | ALA A 60GLY A 61GLY A 83ILE A 82 | None | 0.63A | 4eatA-1qh5A:undetectable | 4eatA-1qh5A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rc2 | AQUAPORIN Z (Escherichiacoli) |
no annotation | 4 | ALA B 65GLY B 220ILE B 218GLY B 215 | None | 0.68A | 4eatA-1rc2B:undetectable | 4eatA-1rc2B:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqj | GERANYLTRANSTRANSFERASE (Escherichiacoli) |
PF00348(polyprenyl_synt) | 4 | ALA A 137ALA A 61GLY A 60ILE A 43 | None | 0.67A | 4eatA-1rqjA:undetectable | 4eatA-1rqjA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sg9 | HEMK PROTEIN (Thermotogamaritima) |
PF05175(MTS) | 4 | ALA A 156ALA A 149ILE A 128GLY A 129 | SAM A 301 ( 4.7A)NoneNoneSAM A 301 (-3.3A) | 0.59A | 4eatA-1sg9A:2.4 | 4eatA-1sg9A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wlt | 176AA LONGHYPOTHETICALDTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (Sulfurisphaeratokodaii) |
PF00908(dTDP_sugar_isom) | 4 | ALA A 84GLY A 70ILE A 72ILE A 73 | None | 0.67A | 4eatA-1wltA:undetectable | 4eatA-1wltA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x68 | FHL5 PROTEIN (Homo sapiens) |
PF00412(LIM) | 4 | ALA A 21GLY A 20GLY A 17ILE A 15 | None | 0.57A | 4eatA-1x68A:undetectable | 4eatA-1x68A:8.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y7r | HYPOTHETICAL PROTEINSA2161 (Staphylococcusaureus) |
PF13673(Acetyltransf_10) | 4 | ALA A 21GLY A 81GLY A 52ILE A 51 | NonePO4 A 504 ( 3.3A)NoneNone | 0.58A | 4eatA-1y7rA:undetectable | 4eatA-1y7rA:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 4 | ALA A 306GLY A 289ILE A 287GLY A 284 | None | 0.61A | 4eatA-2afbA:undetectable | 4eatA-2afbA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d57 | AQUAPORIN-4 (Rattusnorvegicus) |
PF00230(MIP) | 5 | ALA A 215ALA A 130ILE A 128GLY A 125ILE A 127 | None | 0.94A | 4eatA-2d57A:undetectable | 4eatA-2d57A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e54 | ACETYLORNITHINEAMINOTRANSFERASE (Thermotogamaritima) |
PF00202(Aminotran_3) | 4 | ALA A 353ILE A 326GLY A 327ILE A 328 | None | 0.66A | 4eatA-2e54A:undetectable | 4eatA-2e54A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f4n | HYPOTHETICAL PROTEINMJ1651 (Methanocaldococcusjannaschii) |
PF01887(SAM_adeno_trans) | 5 | ALA A 116ALA A 64ILE A 60GLY A 110ILE A 168 | None | 0.89A | 4eatA-2f4nA:undetectable | 4eatA-2f4nA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fe7 | PROBABLEN-ACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | ALA A 97GLY A 98GLY A 64ILE A 63 | None | 0.58A | 4eatA-2fe7A:undetectable | 4eatA-2fe7A:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gp4 | 6-PHOSPHOGLUCONATEDEHYDRATASE (Shewanellaoneidensis) |
PF00920(ILVD_EDD) | 5 | ALA A 314ALA A 165GLY A 164GLY A 169ILE A 278 | None | 1.18A | 4eatA-2gp4A:2.5 | 4eatA-2gp4A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2grj | DEPHOSPHO-COA KINASE (Thermotogamaritima) |
PF01121(CoaE) | 4 | GLY A 7ILE A 9GLY A 10ILE A 131 | NoneCOD A 201 (-3.8A)ADP A 200 (-3.5A)None | 0.67A | 4eatA-2grjA:undetectable | 4eatA-2grjA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzm | GLUTAMATE RACEMASE (Bacillusanthracis) |
PF01177(Asp_Glu_race) | 4 | ALA A 79GLY A 117ILE A 119GLY A 120 | None | 0.68A | 4eatA-2gzmA:2.7 | 4eatA-2gzmA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsd | 3-ALPHA, 20BETA-HYDROXYSTEROIDDEHYDROGENASE (Streptomycesexfoliatus) |
PF13561(adh_short_C2) | 4 | ALA A 88GLY A 17GLY A 14ILE A 11 | NAD A 256 (-3.2A)NAD A 256 (-3.1A)NoneNone | 0.65A | 4eatA-2hsdA:3.7 | 4eatA-2hsdA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kdy | FACTOR H BINDINGPROTEIN VARIANTB01_001 (Neisseriameningitidis) |
PF08794(Lipoprot_C) | 4 | ALA A 114GLY A 169ILE A 255GLY A 256 | None | 0.62A | 4eatA-2kdyA:undetectable | 4eatA-2kdyA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lbf | 60S ACIDIC RIBOSOMALPROTEIN P1 (Homo sapiens) |
PF00428(Ribosomal_60s) | 4 | ALA A 50ALA A 13ILE A 10ILE A 56 | None | 0.63A | 4eatA-2lbfA:undetectable | 4eatA-2lbfA:9.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oce | HYPOTHETICAL PROTEINPA5201 (Pseudomonasaeruginosa) |
PF00575(S1)PF09371(Tex_N)PF12836(HHH_3)PF16921(Tex_YqgF) | 4 | ALA A 424GLY A 333ILE A 389GLY A 390 | None | 0.61A | 4eatA-2oceA:2.7 | 4eatA-2oceA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ow4 | CANAVALIA MARITIMALECTIN (Canavalia rosea) |
PF00139(Lectin_legB) | 4 | ALA A 211ALA A 63GLY A 26ILE A 25 | None | 0.60A | 4eatA-2ow4A:undetectable | 4eatA-2ow4A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5i | BH3822 PROTEIN (Bacillushalodurans) |
PF03099(BPL_LplA_LipB) | 4 | ALA A 142ALA A 164GLY A 165ILE A 129 | None | 0.64A | 4eatA-2p5iA:undetectable | 4eatA-2p5iA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pth | PEPTIDYL-TRNAHYDROLASE (Escherichiacoli) |
PF01195(Pept_tRNA_hydro) | 4 | ALA A 102ALA A 22GLY A 23ILE A 161 | None | 0.56A | 4eatA-2pthA:undetectable | 4eatA-2pthA:20.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2v7b | BENZOATE-COENZYME ALIGASE (Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 7 | ALA A 237TYR A 238ALA A 308GLY A 309ILE A 332GLY A 333ILE A 340 | BEZ A1529 ( 3.7A)BEZ A1529 (-4.3A)BEZ A1529 (-3.6A)BEZ A1529 (-3.5A)NoneBEZ A1529 (-3.6A)BEZ A1529 ( 4.9A) | 0.24A | 4eatA-2v7bA:62.0 | 4eatA-2v7bA:60.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vjh | PHYCOERYTHRIN BETASUBUNIT (Gloeobacterviolaceus) |
PF00502(Phycobilisome) | 4 | ALA B 140ALA B 165GLY B 166ILE B 44 | PUB B1050 ( 4.0A)NoneNoneNone | 0.66A | 4eatA-2vjhB:undetectable | 4eatA-2vjhB:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w2g | NON-STRUCTURALPROTEIN 3 (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF11633(SUD-M) | 4 | ALA A 493GLY A 609ILE A 592ILE A 593 | None | 0.68A | 4eatA-2w2gA:2.3 | 4eatA-2w2gA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wc7 | ALPHA AMYLASE,CATALYTIC REGION (Nostocpunctiforme) |
PF00128(Alpha-amylase)PF11941(DUF3459) | 4 | ALA A 400GLY A 485ILE A 428ILE A 429 | None | 0.65A | 4eatA-2wc7A:undetectable | 4eatA-2wc7A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsu | SPERMIDINE SYNTHASE (Pyrococcushorikoshii) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | GLY A 84ILE A 108GLY A 143ILE A 142 | None | 0.66A | 4eatA-2zsuA:2.3 | 4eatA-2zsuA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clq | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF06545(DUF1116) | 4 | ALA A 159ALA A 122GLY A 121ILE A 99 | None | 0.66A | 4eatA-3clqA:undetectable | 4eatA-3clqA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0g | LEUKEMIA INHIBITORYFACTOR RECEPTOR (Homo sapiens) |
PF00041(fn3) | 4 | ALA A 278GLY A 279GLY A 213ILE A 253 | None | 0.65A | 4eatA-3e0gA:undetectable | 4eatA-3e0gA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7g | UPF0311 PROTEINCA_C3321 (Clostridiumacetobutylicum) |
PF11578(DUF3237) | 5 | ALA A 78ALA A 75ILE A 60GLY A 59ILE A 41 | None | 0.88A | 4eatA-3g7gA:undetectable | 4eatA-3g7gA:15.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga7 | ACETYL ESTERASE (Salmonellaenterica) |
PF07859(Abhydrolase_3) | 4 | ALA A 85ILE A 159GLY A 160ILE A 189 | None | 0.57A | 4eatA-3ga7A:3.4 | 4eatA-3ga7A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hee | RIBOSE-5-PHOSPHATEISOMERASE (Ruminiclostridiumthermocellum) |
PF02502(LacAB_rpiB) | 5 | ALA A 52GLY A 6ILE A 62GLY A 61ILE A 103 | None | 0.79A | 4eatA-3heeA:2.7 | 4eatA-3heeA:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3y | CARBOHYDRATE KINASE (Klebsiellapneumoniae) |
PF00294(PfkB) | 4 | ALA A 41GLY A 40GLY A 37ILE A 36 | None | 0.64A | 4eatA-3i3yA:3.3 | 4eatA-3i3yA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ijp | DIHYDRODIPICOLINATEREDUCTASE (Bartonellahenselae) |
PF01113(DapB_N)PF05173(DapB_C) | 4 | ALA A 64ALA A 8GLY A 7ILE A 57 | NoneNoneNAP A 300 (-3.3A)None | 0.64A | 4eatA-3ijpA:2.4 | 4eatA-3ijpA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcp | GLUCOKINASE (Parabacteroidesdistasonis) |
PF00480(ROK) | 4 | TYR A 79ALA A 77ILE A 83GLY A 82 | None | 0.62A | 4eatA-3mcpA:undetectable | 4eatA-3mcpA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3me5 | CYTOSINE-SPECIFICMETHYLTRANSFERASE (Shigellaflexneri) |
PF00145(DNA_methylase) | 5 | TYR A 124ALA A 94GLY A 95ILE A 99GLY A 98 | None | 1.35A | 4eatA-3me5A:2.4 | 4eatA-3me5A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mqg | LIPOPOLYSACCHARIDESBIOSYNTHESISACETYLTRANSFERASE (Bordetellapetrii) |
PF00132(Hexapep) | 5 | ALA A 141ALA A 107GLY A 106GLY A 122ILE A 121 | None | 1.12A | 4eatA-3mqgA:undetectable | 4eatA-3mqgA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oby | PROTEIN PELOTAHOMOLOG (Archaeoglobusfulgidus) |
PF03463(eRF1_1)PF03464(eRF1_2)PF03465(eRF1_3) | 4 | ALA A 191GLY A 192GLY A 227ILE A 231 | None | 0.68A | 4eatA-3obyA:undetectable | 4eatA-3obyA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ph3 | RIBOSE-5-PHOSPHATEISOMERASE (Ruminiclostridiumthermocellum) |
PF02502(LacAB_rpiB) | 5 | ALA A 52GLY A 6ILE A 62GLY A 61ILE A 103 | None | 0.78A | 4eatA-3ph3A:2.5 | 4eatA-3ph3A:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw3 | OROTIDINE-5-PHOSPHATEDECARBOXYLASE/OROTATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE(OMPDCASE-OPRTASE,PUTATIVE) (Leishmaniainfantum) |
PF00215(OMPdecase) | 4 | ALA A 96TYR A 95GLY A 86ILE A 88 | None | 0.64A | 4eatA-3qw3A:undetectable | 4eatA-3qw3A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9w | GTPASE ERA (Aquifexaeolicus) |
PF01926(MMR_HSR1)PF07650(KH_2) | 4 | ALA A 160GLY A 159ILE A 154ILE A 125 | None | 0.65A | 4eatA-3r9wA:4.6 | 4eatA-3r9wA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ty4 | PROBABLEHOMOISOCITRATEDEHYDROGENASE (Schizosaccharomycespombe) |
PF00180(Iso_dh) | 4 | ALA A 300ALA A 78GLY A 77GLY A 16 | GOL A 365 (-4.0A)NoneNoneNone | 0.68A | 4eatA-3ty4A:undetectable | 4eatA-3ty4A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpp | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 4 | ALA A 343TYR A 342ILE A 273GLY A 274 | None | 0.62A | 4eatA-3zppA:undetectable | 4eatA-3zppA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | ALA A 79ILE A 33GLY A 34ILE A 38 | None | 0.68A | 4eatA-4bedA:undetectable | 4eatA-4bedA:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cok | PYRUVATEDECARBOXYLASE (Gluconacetobacterdiazotrophicus) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ALA A 183ALA A 66GLY A 65GLY A 17 | None | 0.58A | 4eatA-4cokA:4.8 | 4eatA-4cokA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0u | ALLOPHYCOCYANINALPHA CHAIN (Synechococcuselongatus) |
PF00502(Phycobilisome) | 4 | ALA A 142ALA A 162GLY A 163ILE A 44 | None | 0.58A | 4eatA-4f0uA:undetectable | 4eatA-4f0uA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g81 | PUTATIVE HEXONATEDEHYDROGENASE (Salmonellaenterica) |
no annotation | 4 | ALA D 187ILE D 145GLY D 146ILE D 167 | None | 0.68A | 4eatA-4g81D:3.4 | 4eatA-4g81D:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvr | METHENYLTETRAHYDROMETHANOPTERINCYCLOHYDROLASE (Archaeoglobusfulgidus) |
PF02289(MCH) | 4 | ALA A 114GLY A 96GLY A 110ILE A 137 | None | 0.64A | 4eatA-4gvrA:undetectable | 4eatA-4gvrA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hcj | THIJ/PFPI DOMAINPROTEIN (Brachyspiramurdochii) |
PF01965(DJ-1_PfpI) | 5 | ALA A 165ALA A 102GLY A 103ILE A 150ILE A 100 | None | 1.13A | 4eatA-4hcjA:undetectable | 4eatA-4hcjA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hds | ARSA (Sporomusa ovata) |
PF02277(DBI_PRT) | 4 | ALA A 222ALA A 191GLY A 190ILE A 188 | None | 0.65A | 4eatA-4hdsA:undetectable | 4eatA-4hdsA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkm | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Xanthomonascampestris) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | ALA A 60GLY A 59ILE A 57ILE A 178 | None | 0.65A | 4eatA-4hkmA:undetectable | 4eatA-4hkmA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4is2 | BILE ACID 3-ALPHAHYDROXYSTEROIDDEHYDROGENASE ([Clostridium]scindens) |
PF00106(adh_short) | 4 | ALA A 93GLY A 17GLY A 14ILE A 11 | None | 0.67A | 4eatA-4is2A:3.7 | 4eatA-4is2A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,N-TERMINAL DOMAINPROTEIN (Paracoccusdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ALA A 129ALA A 121ILE A 308GLY A 309 | None | 0.51A | 4eatA-4izgA:undetectable | 4eatA-4izgA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbh | ALCOHOLDEHYDROGENASE (ZINC) (Pyrobaculumaerophilum) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ALA A 52GLY A 111ILE A 113GLY A 114 | None | 0.67A | 4eatA-4jbhA:5.1 | 4eatA-4jbhA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlv | C-TERMINAL FRAGMENTOF MEMBRANE PROTEINCAPA1, PUTATIVEUNCHARACTERIZEDPROTEIN CAPB1 (Staphylococcusaureus) |
PF13614(AAA_31) | 4 | ALA A1067TYR A1066ILE A1154ILE A1155 | None | 0.63A | 4eatA-4jlvA:2.8 | 4eatA-4jlvA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k25 | PROBABLE TRNATHREONYLCARBAMOYLADENOSINE BIOSYNTHESISPROTEIN QRI7,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00814(Peptidase_M22) | 4 | ALA A 37GLY A 142ILE A 373GLY A 370 | None | 0.63A | 4eatA-4k25A:undetectable | 4eatA-4k25A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0d | N-ACETYLMURAMIC ACID6-PHOSPHATE ETHERASE (Haemophilusinfluenzae) |
PF01380(SIS) | 4 | GLY A 103ILE A 74GLY A 75ILE A 144 | None | 0.64A | 4eatA-4m0dA:undetectable | 4eatA-4m0dA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mr0 | PLASMIN ANDFIBRONECTIN-BINDINGPROTEIN A (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 4 | ALA A 354TYR A 353ILE A 284GLY A 285 | None | 0.65A | 4eatA-4mr0A:undetectable | 4eatA-4mr0A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mup | AMIDOHYDROLASE (Agrobacteriumfabrum) |
PF04909(Amidohydro_2) | 5 | ALA A 16ALA A 21GLY A 20ILE A 62GLY A 61 | None | 1.38A | 4eatA-4mupA:undetectable | 4eatA-4mupA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n80 | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | ALA A 396TYR A 397ILE A 243GLY A 244 | None | 0.50A | 4eatA-4n80A:undetectable | 4eatA-4n80A:25.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o0l | NADPH-DEPENDENT3-QUINUCLIDINONEREDUCTASE (Rhodotorulamucilaginosa) |
PF13561(adh_short_C2) | 4 | ALA A 114GLY A 39GLY A 36ILE A 33 | NDP A 300 (-3.7A)NDP A 300 (-3.7A)NoneNone | 0.68A | 4eatA-4o0lA:3.2 | 4eatA-4o0lA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r37 | PUTATIVEACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Bacteroidesfragilis) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 4 | TYR A 212ILE A 179GLY A 189ILE A 190 | None | 0.68A | 4eatA-4r37A:undetectable | 4eatA-4r37A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rhh | BETA-XYLOSIDASE (Geobacillusstearothermophilus) |
PF03512(Glyco_hydro_52) | 4 | GLY A 162ILE A 45GLY A 46ILE A 58 | None | 0.68A | 4eatA-4rhhA:undetectable | 4eatA-4rhhA:22.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4rlq | BENZOATE-COENZYME ALIGASE (Rhodopseudomonaspalustris) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 7 | ALA A 227TYR A 228ALA A 302GLY A 303ILE A 326GLY A 327ILE A 334 | 3SK A1000 (-3.6A)3SK A1000 (-4.8A)3SK A1000 ( 3.8A)3SK A1000 (-3.3A)3SK A1000 (-4.4A)3SK A1000 (-3.6A)None | 0.10A | 4eatA-4rlqA:73.0 | 4eatA-4rlqA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tuf | MAJOR EXTRACELLULARENDOGLUCANASE (Xanthomonascampestris) |
PF00150(Cellulase) | 4 | ALA A 294GLY A 295GLY A 330ILE A 331 | None | 0.63A | 4eatA-4tufA:undetectable | 4eatA-4tufA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u36 | SEED LECTIN (Vataireamacrocarpa) |
PF00139(Lectin_legB) | 4 | ALA A 90ALA A 176GLY A 139ILE A 138 | None | 0.68A | 4eatA-4u36A:undetectable | 4eatA-4u36A:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wec | SHORT CHAINDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 4 | ALA A 89GLY A 20GLY A 17ILE A 14 | NAD A 301 ( 4.0A)NAD A 301 (-3.1A)NAD A 301 ( 4.8A)None | 0.64A | 4eatA-4wecA:4.2 | 4eatA-4wecA:20.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wv3 | ANTHRANILATE-COALIGASE (Stigmatellaaurantiaca) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ALA A 293ILE A 317GLY A 318ILE A 325 | 3UK A 601 (-3.5A)3UK A 601 (-4.0A)3UK A 601 (-3.5A)None | 0.33A | 4eatA-4wv3A:57.4 | 4eatA-4wv3A:42.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yfl | 1B2530 HEAVY CHAIN (Homo sapiens) |
no annotation | 4 | TYR H 54GLY H 56ILE H 51ILE H 33 | None | 0.66A | 4eatA-4yflH:undetectable | 4eatA-4yflH:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpj | EXTRACELLULARLIGAND-BINDINGRECEPTOR (Sphaerobacterthermophilus) |
PF13458(Peripla_BP_6) | 4 | ALA A 151GLY A 152GLY A 370ILE A 374 | None | 0.67A | 4eatA-4zpjA:5.4 | 4eatA-4zpjA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | ALA A1389ALA A1468GLY A1467ILE A1465 | None | 0.57A | 4eatA-5a31A:undetectable | 4eatA-5a31A:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hci | GPN-LOOP GTPASE 1 (Saccharomycescerevisiae) |
PF03029(ATP_bind_1) | 4 | GLY A 109ILE A 111GLY A 10ILE A 9 | GDP A 301 ( 4.4A)NoneNoneNone | 0.67A | 4eatA-5hciA:undetectable | 4eatA-5hciA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy7 | TRANSCRIPTIONINITIATION FACTORIIB (Homo sapiens) |
PF00382(TFIIB)PF08271(TF_Zn_Ribbon) | 4 | ALA M 256ALA M 278GLY M 275ILE M 251 | None | 0.65A | 4eatA-5iy7M:undetectable | 4eatA-5iy7M:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | ALA A1389ALA A1468GLY A1467ILE A1465 | None | 0.60A | 4eatA-5lcwA:undetectable | 4eatA-5lcwA:13.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ly3 | ACTIN/ACTIN FAMILYPROTEIN (Pyrobaculumcalidifontis) |
PF00022(Actin) | 4 | ALA A 130GLY A 410ILE A 408GLY A 405 | None | 0.61A | 4eatA-5ly3A:undetectable | 4eatA-5ly3A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd5 | TRANSKETOLASE (Chlamydomonasreinhardtii) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | ALA A 506GLY A 467GLY A 472ILE A 473 | None | 0.65A | 4eatA-5nd5A:undetectable | 4eatA-5nd5A:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o3m | PROTOCATECHUATEDECARBOXYLASE (Klebsiellapneumoniae) |
PF01977(UbiD) | 4 | ALA A 77GLY A 74GLY A 55ILE A 54 | None | 0.60A | 4eatA-5o3mA:2.7 | 4eatA-5o3mA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oe5 | ANTHRANILATE--COALIGASE (Pseudomonasaeruginosa) |
PF00501(AMP-binding) | 5 | TYR A 211ALA A 278GLY A 279ILE A 301GLY A 302 | 3UK A 900 (-4.0A)3UK A 900 ( 2.9A)3UK A 900 (-3.2A)3UK A 900 (-4.0A)3UK A 900 (-3.4A) | 0.38A | 4eatA-5oe5A:49.3 | 4eatA-5oe5A:28.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5u2a | AMP-DEPENDENTSYNTHETASE ANDLIGASE (Brucella canis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | ALA A 250TYR A 251ALA A 322GLY A 323 | None | 0.49A | 4eatA-5u2aA:43.0 | 4eatA-5u2aA:32.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5u2a | AMP-DEPENDENTSYNTHETASE ANDLIGASE (Brucella canis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | TYR A 251ALA A 322GLY A 323GLY A 347 | None | 0.54A | 4eatA-5u2aA:43.0 | 4eatA-5u2aA:32.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wxu | 11S GLOBULIN (Wrightiatinctoria) |
no annotation | 4 | ALA A 170ILE A 112GLY A 111ILE A 154 | None | 0.66A | 4eatA-5wxuA:undetectable | 4eatA-5wxuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S4 (Trichomonasvaginalis) |
PF00900(Ribosomal_S4e)PF01479(S4)PF08071(RS4NT)PF16121(40S_S4_C) | 4 | ALA E 119GLY E 74GLY E 91ILE E 90 | None | 0.55A | 4eatA-5xyiE:undetectable | 4eatA-5xyiE:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6q | ALDEHYDE OXIDASESMALL SUBUNIT (Methylobacillussp. KY4400) |
no annotation | 4 | ALA A 155ALA A 123GLY A 124ILE A 150 | None | 0.59A | 4eatA-5y6qA:undetectable | 4eatA-5y6qA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d9y | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
no annotation | 4 | ALA A 92GLY A 19GLY A 16ILE A 13 | None | 0.65A | 4eatA-6d9yA:3.3 | 4eatA-6d9yA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu6 | AMMONIUM TRANSPORTER (CandidatusKueneniastuttgartiensis) |
no annotation | 4 | GLY A 73ILE A 75GLY A 76ILE A 77 | None | 0.64A | 4eatA-6eu6A:undetectable | 4eatA-6eu6A:undetectable |