SIMILAR PATTERNS OF AMINO ACIDS FOR 4DTA_A_ADNA401
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bp1 | BACTERICIDAL/PERMEABILITY-INCREASINGPROTEIN (Homo sapiens) |
PF01273(LBP_BPI_CETP)PF02886(LBP_BPI_CETP_C) | 5 | LYS A 420PRO A 426ILE A 205ILE A 199ASP A 200 | PC1 A 778 (-4.5A)NoneNoneNonePC1 A 778 ( 4.6A) | 1.31A | 4dtaA-1bp1A:undetectable | 4dtaA-1bp1A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cv8 | STAPHOPAIN (Staphylococcusaureus) |
PF05543(Peptidase_C47) | 5 | ALA A 25PRO A 81ILE A 71LEU A 83ILE A 171 | E64 A 176 ( 4.1A)NoneNoneNoneNone | 1.33A | 4dtaA-1cv8A:undetectable | 4dtaA-1cv8A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 5 | ALA A 41ILE A 446HIS A 423ILE A 254ASP A 253 | None | 1.08A | 4dtaA-1e1cA:undetectable | 4dtaA-1e1cA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebd | DIHYDROLIPOAMIDEDEHYDROGENASE (Geobacillusstearothermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 325ILE A 312LYS A 324ILE A 145ILE A 315 | FAD A 462 ( 3.7A)NoneNoneNoneNone | 1.19A | 4dtaA-1ebdA:undetectable | 4dtaA-1ebdA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pwe | L-SERINE DEHYDRATASE (Rattusnorvegicus) |
PF00291(PALP) | 5 | ALA A 315PRO A 268ILE A 255LEU A 265ILE A 308 | None | 1.08A | 4dtaA-1pweA:undetectable | 4dtaA-1pweA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rj7 | ECTODYSPLASIN A (Homo sapiens) |
PF00229(TNF) | 5 | ALA A 318ILE A 369ILE A 260LEU A 271ILE A 371 | None | 1.20A | 4dtaA-1rj7A:undetectable | 4dtaA-1rj7A:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlm | PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 5 | ALA A 236PRO A 159ILE A 162ILE A 158ASP A 155 | None | 1.15A | 4dtaA-1rlmA:2.1 | 4dtaA-1rlmA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 5 | ALA A 191ILE A 173LEU A 155ILE A 168ASP A 166 | None | 0.97A | 4dtaA-1s4dA:undetectable | 4dtaA-1s4dA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1un9 | DIHYDROXYACETONEKINASE (Citrobacterfreundii) |
PF02733(Dak1)PF02734(Dak2) | 5 | ALA A 153ILE A 156PRO A 328LEU A 318ILE A 289 | None | 1.04A | 4dtaA-1un9A:undetectable | 4dtaA-1un9A:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjq | DESIGNED PROTEIN (-) |
PF02244(Propep_M14) | 5 | ALA A 21PRO A 8ILE A 62LEU A 57ILE A 6 | None | 1.01A | 4dtaA-1vjqA:undetectable | 4dtaA-1vjqA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yad | REGULATORY PROTEINTENI (Bacillussubtilis) |
PF02581(TMP-TENI) | 5 | PRO A 85ILE A 88HIS A 96LEU A 95ASP A 116 | None | 1.26A | 4dtaA-1yadA:undetectable | 4dtaA-1yadA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zao | RIO2 SERINE KINASE (Archaeoglobusfulgidus) |
PF01163(RIO1)PF09202(Rio2_N) | 5 | LYS A 120PRO A 167ILE A 182LEU A 225ILE A 234 | ATP A 286 (-2.6A)ATP A 286 ( 4.7A)ATP A 286 (-4.2A)NoneATP A 286 (-4.5A) | 0.93A | 4dtaA-1zaoA:10.6 | 4dtaA-1zaoA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7j | SEP-TRNA:CYS-TRNASYNTHASE (Archaeoglobusfulgidus) |
PF05889(SepSecS) | 5 | ALA A 81ILE A 254HIS A 208LEU A 257ILE A 217 | NoneNonePLP A1209 (-3.5A)NoneNone | 1.10A | 4dtaA-2e7jA:undetectable | 4dtaA-2e7jA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gx8 | NIF3-RELATED PROTEIN (Bacillus cereus) |
PF01784(NIF3) | 5 | ALA A 57ILE A 97ILE A 33LEU A 71ILE A 99 | None | 1.24A | 4dtaA-2gx8A:undetectable | 4dtaA-2gx8A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hrz | NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE (Agrobacteriumfabrum) |
PF01370(Epimerase) | 5 | ALA A 79PRO A 128ILE A 117LEU A 113ILE A 84 | None | 1.18A | 4dtaA-2hrzA:undetectable | 4dtaA-2hrzA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2izo | FLAPSTRUCTURE-SPECIFICENDONUCLEASE (Sulfolobussolfataricus) |
PF00752(XPG_N)PF00867(XPG_I) | 5 | ILE A 71LYS A 334PRO A 142ILE A 73ASP A 295 | None | 1.27A | 4dtaA-2izoA:undetectable | 4dtaA-2izoA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k75 | UNCHARACTERIZEDPROTEIN TA0387 (Thermoplasmaacidophilum) |
no annotation | 5 | ALA A 71ILE A 68ILE A 22LEU A 60ILE A 53 | None | 1.29A | 4dtaA-2k75A:undetectable | 4dtaA-2k75A:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1d | 2-KETO-3-DEOXY-D-ARABINONATE DEHYDRATASE (Sulfolobussolfataricus) |
PF01557(FAA_hydrolase) | 5 | ALA X 147ILE X 251PRO X 70LEU X 34ILE X 194 | None | 1.15A | 4dtaA-2q1dX:undetectable | 4dtaA-2q1dX:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q83 | YTAA PROTEIN (Bacillussubtilis) |
PF01636(APH) | 5 | LYS A 72PRO A 99ILE A 124LEU A 246ILE A 256 | NoneADN A 1 ( 4.9A)ADN A 1 (-4.6A)NoneADN A 1 ( 4.6A) | 0.79A | 4dtaA-2q83A:15.2 | 4dtaA-2q83A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qip | PROTEIN OF UNKNOWNFUNCTION VPA0982 (Vibrioparahaemolyticus) |
PF01936(NYN) | 5 | ALA A 10ILE A 102ILE A 100LEU A 121ILE A 125 | None | 1.04A | 4dtaA-2qipA:undetectable | 4dtaA-2qipA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9q | 2'-DEOXYCYTIDINE5'-TRIPHOSPHATEDEAMINASE (Agrobacteriumfabrum) |
PF06559(DCD) | 5 | ALA A 85PRO A 151ILE A 122LEU A 164ILE A 149 | None | 1.09A | 4dtaA-2r9qA:undetectable | 4dtaA-2r9qA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsv | RHOPHILIN-2 (Homo sapiens) |
no annotation | 5 | ALA A 550ILE A 517ILE A 561LEU A 578ILE A 586 | None | 1.04A | 4dtaA-2vsvA:undetectable | 4dtaA-2vsvA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vwb | PUTATIVEO-SIALOGLYCOPROTEINENDOPEPTIDASE (Methanocaldococcusjannaschii) |
PF00814(Peptidase_M22)PF01163(RIO1) | 5 | ILE A 358LYS A 360PRO A 399ILE A 416ILE A 466 | None | 0.93A | 4dtaA-2vwbA:3.0 | 4dtaA-2vwbA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x58 | PEROXISOMALBIFUNCTIONAL ENZYME (Rattusnorvegicus) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | ALA A 666ILE A 627LEU A 634ILE A 645ASP A 646 | None | 1.25A | 4dtaA-2x58A:undetectable | 4dtaA-2x58A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x58 | PEROXISOMALBIFUNCTIONAL ENZYME (Rattusnorvegicus) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | ALA A 666ILE A 633LEU A 634ILE A 645ASP A 646 | None | 1.29A | 4dtaA-2x58A:undetectable | 4dtaA-2x58A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhm | NUCLEOPROTEIN (Humanorthopneumovirus) |
PF03246(Pneumo_ncap) | 5 | ALA A 206ILE A 163ILE A 159LEU A 52ILE A 160 | None | 1.27A | 4dtaA-2yhmA:undetectable | 4dtaA-2yhmA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2x | TK-SUBTILISIN (Thermococcuskodakarensis) |
PF00082(Peptidase_S8) | 5 | ALA A 227ILE A 204ILE A 200LEU A 114ILE A 231 | CA A1006 (-4.9A)NoneNoneNoneNone | 1.25A | 4dtaA-2z2xA:undetectable | 4dtaA-2z2xA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bed | PTS SYSTEM, IIACOMPONENT (Enterococcusfaecalis) |
PF03610(EIIA-man) | 5 | ALA A 14ILE A 33ILE A 52LEU A 49ILE A 6 | None | 1.18A | 4dtaA-3bedA:undetectable | 4dtaA-3bedA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bws | PROTEIN LP49 (Leptospirainterrogans) |
PF10282(Lactonase) | 5 | ILE A 239PRO A 279ILE A 293LEU A 291ILE A 259 | None | 1.02A | 4dtaA-3bwsA:2.3 | 4dtaA-3bwsA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cg1 | UPF0100 PROTEINPF0080 (Pyrococcusfuriosus) |
PF13531(SBP_bac_11) | 5 | ALA A 201ILE A 192ILE A 212ILE A 214ASP A 156 | None | 1.30A | 4dtaA-3cg1A:undetectable | 4dtaA-3cg1A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dg7 | MUCONATECYCLOISOMERASE (Mycolicibacteriumsmegmatis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 302ILE A 353ILE A 355HIS A 31LEU A 33 | None | 1.20A | 4dtaA-3dg7A:undetectable | 4dtaA-3dg7A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm9 | SIGNAL RECOGNITIONPARTICLE RECEPTOR (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N) | 5 | ALA B 194ILE B 211ILE B 140LEU B 170ILE B 156 | None | 1.24A | 4dtaA-3dm9B:2.0 | 4dtaA-3dm9B:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dmy | PROTEIN FDRA (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | ALA A 111ILE A 514ILE A 123LEU A 133ILE A 516 | None | 1.17A | 4dtaA-3dmyA:undetectable | 4dtaA-3dmyA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dxi | PUTATIVE ALDOLASE (Bacteroidesvulgatus) |
PF00682(HMGL-like) | 5 | ALA A 114ILE A 104ILE A 102LEU A 92ILE A 121 | None | 1.20A | 4dtaA-3dxiA:undetectable | 4dtaA-3dxiA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e05 | PRECORRIN-6YC5,15-METHYLTRANSFERASE(DECARBOXYLATING) (Geobactermetallireducens) |
no annotation | 5 | ALA A 400ILE A 346ILE A 332LEU A 329ILE A 333 | None | 1.15A | 4dtaA-3e05A:undetectable | 4dtaA-3e05A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e18 | OXIDOREDUCTASE (Listeriainnocua) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 335ILE A 336ILE A 224LEU A 183ILE A 214 | None | 1.16A | 4dtaA-3e18A:undetectable | 4dtaA-3e18A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7o | MITOGEN-ACTIVATEDPROTEIN KINASE 9 (Homo sapiens) |
PF00069(Pkinase) | 5 | ALA A 113PRO A 154ILE A 214LEU A 218ILE A 119 | 35F A 1 (-4.9A)NoneNoneNoneNone | 1.31A | 4dtaA-3e7oA:8.1 | 4dtaA-3e7oA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7w | PUTATIVEFRUCTOSAMINE-3-KINASE (Thermobifidafusca) |
PF03881(Fructosamin_kin) | 5 | LYS A 44PRO A 76LEU A 200ILE A 209ASP A 210 | EDO A 293 (-3.0A)NoneNoneUNL A 288 (-3.6A)None | 0.78A | 4dtaA-3f7wA:16.6 | 4dtaA-3f7wA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdo | UNCHARACTERIZEDOXIDOREDUCTASE YVAA (Bacillussubtilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 110ILE A 338ILE A 191LEU A 195ILE A 340 | None | 1.19A | 4dtaA-3gdoA:undetectable | 4dtaA-3gdoA:25.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ham | AMINOGLYCOSIDEPHOSPHOTRANSFERASE (Enterococcusfaecium) |
PF01636(APH) | 5 | LYS A 42PRO A 73ILE A 88ILE A 209ASP A 210 | None | 0.74A | 4dtaA-3hamA:21.3 | 4dtaA-3hamA:34.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjg | PUTATIVEALPHA-RIBAZOLE-5'-PHOSPHATE PHOSPHATASECOBC (Vibrioparahaemolyticus) |
PF00300(His_Phos_1) | 5 | ILE A 135ILE A 154HIS A 181LEU A 8ILE A 182 | None | 1.30A | 4dtaA-3hjgA:undetectable | 4dtaA-3hjgA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hpf | MUCONATECYCLOISOMERASE (Oceanobacillusiheyensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 305ILE A 25LEU A 359ILE A 37ASP A 106 | None | 1.30A | 4dtaA-3hpfA:undetectable | 4dtaA-3hpfA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2k | PUTATIVECARBOXYPEPTIDASE (Burkholderiamallei) |
PF00246(Peptidase_M14) | 5 | ALA A 132PRO A 213ILE A 181LEU A 184ILE A 211 | None | 1.20A | 4dtaA-3k2kA:undetectable | 4dtaA-3k2kA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kmi | PUTATIVE MEMBRANEPROTEIN COG4129 (Clostridioidesdifficile) |
PF11728(ArAE_1_C) | 5 | ALA A 245ILE A 172ILE A 168LEU A 231ILE A 252 | None | 1.31A | 4dtaA-3kmiA:undetectable | 4dtaA-3kmiA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kom | TRANSKETOLASE (Francisellatularensis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ILE A 537ILE A 345LEU A 349ILE A 498ASP A 496 | None | 1.28A | 4dtaA-3komA:undetectable | 4dtaA-3komA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldg | PUTATIVEUNCHARACTERIZEDPROTEIN SMU.472 (Streptococcusmutans) |
PF01170(UPF0020)PF02926(THUMP) | 5 | ALA A 118ILE A 114ILE A 111LEU A 148ILE A 146 | None | 1.16A | 4dtaA-3ldgA:undetectable | 4dtaA-3ldgA:22.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n4t | APH(2'')-ID (Enterococcuscasseliflavus) |
PF01636(APH) | 10 | ALA A 36ILE A 44LYS A 46PRO A 76LYS A 97ILE A 98HIS A 202LEU A 204ILE A 216ASP A 217 | None | 0.42A | 4dtaA-3n4tA:43.0 | 4dtaA-3n4tA:99.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3on4 | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Legionellapneumophila) |
PF00440(TetR_N) | 5 | ALA A 91ILE A 92ILE A 157LEU A 135ILE A 131 | None | 1.27A | 4dtaA-3on4A:undetectable | 4dtaA-3on4A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ory | FLAP ENDONUCLEASE 1 (Desulfurococcusamylolyticus) |
PF00752(XPG_N)PF00867(XPG_I) | 5 | ALA A 35PRO A 79ILE A 77LEU A 20ILE A 72 | None | 1.20A | 4dtaA-3oryA:undetectable | 4dtaA-3oryA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4w | FANCONI ANEMIA GROUPD2 PROTEIN HOMOLOG (Mus musculus) |
PF14631(FancD2) | 5 | ALA B 201PRO B 242ILE B 243LEU B 229ILE B 210 | None | 1.19A | 4dtaA-3s4wB:2.1 | 4dtaA-3s4wB:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t57 | UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASEDOMAIN-CONTAININGPROTEIN (Arabidopsisthaliana) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ILE A 184ILE A 142HIS A 155LEU A 140ILE A 154 | None | 1.31A | 4dtaA-3t57A:undetectable | 4dtaA-3t57A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdw | GENTAMICINRESISTANCE PROTEIN (Enterococcusgallinarum) |
PF01636(APH) | 6 | ALA A 35PRO A 75LYS A 94HIS A 201LEU A 203ILE A 217 | GDP A 500 (-3.6A)NoneGDP A 500 (-4.3A) MG A 501 ( 3.4A)NoneGDP A 500 ( 4.1A) | 0.65A | 4dtaA-3tdwA:29.7 | 4dtaA-3tdwA:29.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tny | YFIY (ABC TRANSPORTSYSTEMSUBSTRATE-BINDINGPROTEIN) (Bacillus cereus) |
PF01497(Peripla_BP_2) | 5 | ALA A 43PRO A 82ILE A 102LEU A 99ILE A 85 | None | 1.29A | 4dtaA-3tnyA:undetectable | 4dtaA-3tnyA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0f | BETA-KETOACYLSYNTHASE (Brucellaabortus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ILE A 314PRO A 322ILE A 293LEU A 387ILE A 290 | None | 1.28A | 4dtaA-3u0fA:undetectable | 4dtaA-3u0fA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgf | MALTO-OLIGOSYLTREHALOSE TREHALOHYDROLASE (Sulfolobussolfataricus) |
PF00128(Alpha-amylase)PF09071(Alpha-amyl_C) | 5 | LYS A 231ILE A 233HIS A 264ILE A 265ASP A 259 | None | 1.26A | 4dtaA-3vgfA:2.4 | 4dtaA-3vgfA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a05 | CELLOBIOHYDROLASEFAMILY 6 (Chaetomiumthermophilum) |
PF01341(Glyco_hydro_6) | 5 | ALA A 331ILE A 378PRO A 120LEU A 126ILE A 246 | None | 1.24A | 4dtaA-4a05A:undetectable | 4dtaA-4a05A:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc7 | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE,PEROXISOMAL (Cavia porcellus) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | PRO A 415ILE A 408HIS A 419LEU A 405ILE A 418 | None | 1.25A | 4dtaA-4bc7A:undetectable | 4dtaA-4bc7A:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3s | ALDEHYDEDEHYDROGENASE (Lachnoclostridiumphytofermentans) |
PF00171(Aldedh) | 5 | ILE A 148ILE A 176HIS A 95LEU A 175ILE A 144 | None | 1.28A | 4dtaA-4c3sA:undetectable | 4dtaA-4c3sA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4da5 | CHOLINE KINASE ALPHA (Homo sapiens) |
PF01633(Choline_kinase) | 5 | PRO A 194ILE A 209LEU A 313ILE A 329ASP A 330 | None | 1.04A | 4dtaA-4da5A:5.3 | 4dtaA-4da5A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl0 | AMINOTRANSFERASEALD1 (Arabidopsisthaliana) |
PF00155(Aminotran_1_2) | 5 | ILE A 345PRO A 85ILE A 84HIS A 91ILE A 88 | None | 1.16A | 4dtaA-4fl0A:undetectable | 4dtaA-4fl0A:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmw | RNA(GUANINE-9-)-METHYLTRANSFERASEDOMAIN-CONTAININGPROTEIN 2 (Homo sapiens) |
PF01746(tRNA_m1G_MT) | 5 | ALA A 130ILE A 105HIS A 122LEU A 143ILE A 125 | None | 1.10A | 4dtaA-4fmwA:undetectable | 4dtaA-4fmwA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfj | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 5 | ALA A 581ILE A 568ILE A 565LEU A 552ILE A 562 | None | 1.24A | 4dtaA-4gfjA:2.2 | 4dtaA-4gfjA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvl | TRKA DOMAIN PROTEIN (Geobactersulfurreducens) |
PF02080(TrkA_C)PF02254(TrkA_N) | 5 | ALA A 506PRO A 533ILE A 521LEU A 545ILE A 518 | None | 1.19A | 4dtaA-4gvlA:undetectable | 4dtaA-4gvlA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h27 | L-SERINEDEHYDRATASE/L-THREONINE DEAMINASE (Homo sapiens) |
PF00291(PALP) | 5 | ALA A 315PRO A 268ILE A 255LEU A 265ILE A 308 | None | 1.11A | 4dtaA-4h27A:undetectable | 4dtaA-4h27A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kws | D-MANNONATEDEHYDRATASE (Chromohalobactersalexigens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 223ILE A 253ILE A 282LEU A 276ILE A 263 | None | 1.29A | 4dtaA-4kwsA:undetectable | 4dtaA-4kwsA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lqz | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF16253(DUF4909) | 5 | ALA A 65ILE A 83ILE A 38LEU A 154ILE A 48 | None | 1.12A | 4dtaA-4lqzA:undetectable | 4dtaA-4lqzA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4na3 | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A 200ILE A 183ILE A 442LEU A 374ILE A 9 | None | 1.08A | 4dtaA-4na3A:undetectable | 4dtaA-4na3A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ALA A 320ILE A 266ILE A 362LEU A 341ILE A 349 | None | 1.07A | 4dtaA-4tr6A:undetectable | 4dtaA-4tr6A:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkz | VALINE-TRNA LIGASE (Pseudomonasaeruginosa) |
PF08264(Anticodon_1) | 5 | ALA A 867ILE A 809ILE A 821LEU A 849ILE A 823 | None | 1.21A | 4dtaA-4xkzA:undetectable | 4dtaA-4xkzA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xt1 | G-PROTEIN COUPLEDRECEPTOR HOMOLOGUS28NANOBODY 7 (Cytomegalovirus;Vicugna pacos) |
PF00001(7tm_1)PF07686(V-set) | 5 | ALA A 132ILE A 133ILE A 226LEU A 230ILE C 101 | None | 1.31A | 4dtaA-4xt1A:undetectable | 4dtaA-4xt1A:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg7 | SERINE/THREONINE-PROTEIN KINASE HIPA (Escherichiacoli) |
PF07804(HipA_C)PF13657(Couple_hipA) | 5 | ALA D 421ILE D 366HIS D 346LEU D 350ILE D 347 | None | 1.24A | 4dtaA-4yg7D:5.1 | 4dtaA-4yg7D:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ykn | PHOSPHATIDYLINOSITOL3-KINASE REGULATORYSUBUNITALPHA,PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT ALPHAISOFORM FUSIONPROTEIN (Homo sapiens) |
PF00017(SH2)PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd)PF02192(PI3K_p85B)PF16454(PI3K_P85_iSH2) | 5 | ILE A1816ILE A1910HIS A1994LEU A2026ILE A1991 | None | 1.24A | 4dtaA-4yknA:2.8 | 4dtaA-4yknA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z37 | PUTATIVE MIXEDPOLYKETIDESYNTHASE/NON-RIBOSOMAL PEPTIDESYNTHETASE (Brevibacillusbrevis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A2520ILE A2503ILE A2756LEU A2685ILE A2325 | None | 1.08A | 4dtaA-4z37A:undetectable | 4dtaA-4z37A:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ck7 | ADP-DEPENDENTGLUCOKINASE (Mus musculus) |
PF04587(ADP_PFK_GK) | 5 | ILE A 357ILE A 378HIS A 365LEU A 321ILE A 361 | None | 1.13A | 4dtaA-5ck7A:undetectable | 4dtaA-5ck7A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7s | LON PROTEASE (Meiothermustaiwanensis) |
PF05362(Lon_C) | 5 | ALA A 502ILE A 527ILE A 574LEU A 578ILE A 550 | None | 1.07A | 4dtaA-5e7sA:undetectable | 4dtaA-5e7sA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erb | POLYKETIDE SYNTHASE (Bacillusamyloliquefaciens) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A 207ILE A 190ILE A 443LEU A 372ILE A 11 | None | 1.10A | 4dtaA-5erbA:undetectable | 4dtaA-5erbA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fi5 | TETRAHYDROALSTONINESYNTHASE (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 195ILE A 185ILE A 209LEU A 260ILE A 247 | None | 1.27A | 4dtaA-5fi5A:undetectable | 4dtaA-5fi5A:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gus | HELIX-TURN-HELIXDOMAIN-CONTAININGPROTEIN (Zymomonasmobilis) |
PF04266(ASCH) | 5 | ALA A 10ILE A 44ILE A 22LEU A 14ILE A 46 | None | 1.21A | 4dtaA-5gusA:undetectable | 4dtaA-5gusA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gxd | AMP-DEPENDENTSYNTHETASE ANDLIGASE (Dinoroseobactershibae) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 5 | ALA A 155PRO A 190ILE A 183LEU A 179ILE A 160 | None | 1.27A | 4dtaA-5gxdA:undetectable | 4dtaA-5gxdA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izt | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 5 | ALA A 232ILE A 298ILE A 388LEU A 368ILE A 284 | None | 1.19A | 4dtaA-5iztA:undetectable | 4dtaA-5iztA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jd8 | PERIPLASMIC SERINEPEPTIDASE DEGS (Yersinia pestis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ILE A 258ILE A 303HIS A 298LEU A 334ILE A 297 | None | 1.24A | 4dtaA-5jd8A:undetectable | 4dtaA-5jd8A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8p | S-LAYER PROTEIN (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | ALA A 924ILE A 921ILE A 909LEU A 932ILE A1005 | None | 1.31A | 4dtaA-5n8pA:undetectable | 4dtaA-5n8pA:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n97 | S-LAYER PROTEIN RSAA (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 5 | ALA A 924ILE A 921ILE A 909LEU A 932ILE A1005 | None | 1.31A | 4dtaA-5n97A:undetectable | 4dtaA-5n97A:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nhs | BIFUNCTIONAL PROTEINFOLD (Xanthomonasalbilineans) |
no annotation | 5 | ALA A 34PRO A 43ILE A 72ILE A 287ASP A 291 | None | 1.20A | 4dtaA-5nhsA:undetectable | 4dtaA-5nhsA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5njf | METALLOPROTEASE PMBA (Escherichiacoli) |
PF01523(PmbA_TldD) | 5 | ALA B 263ILE B 264ILE B 319LEU B 285ILE B 284 | None | 1.18A | 4dtaA-5njfB:undetectable | 4dtaA-5njfB:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tv2 | ELONGATION FACTOR G (Vibriovulnificus) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2) | 5 | ALA A 281ILE A 248LEU A 222ILE A 186ASP A 184 | None | 1.25A | 4dtaA-5tv2A:undetectable | 4dtaA-5tv2A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2i | NUCLEOSIDEDIPHOSPHATE KINASE (Naegleriafowleri) |
PF00334(NDK) | 5 | ALA A 86ILE A 90ILE A 115LEU A 10ILE A 23 | None | 1.12A | 4dtaA-5u2iA:undetectable | 4dtaA-5u2iA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | ALA A 15ILE A 17ILE A 146LEU A 189ILE A 144 | NoneNoneNAP A 301 (-4.4A)NoneNone | 1.30A | 4dtaA-5u9pA:undetectable | 4dtaA-5u9pA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux5 | BIFUNCTIONAL PROTEINPROLINE UTILIZATIONA (PUTA) (Corynebacteriumfreiburgense) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | ALA A 358ILE A 347ILE A 293LEU A 273ILE A 335 | None | 1.19A | 4dtaA-5ux5A:undetectable | 4dtaA-5ux5A:13.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1s | RADICAL SAM (Streptococcussuis) |
PF04055(Radical_SAM)PF13394(Fer4_14) | 5 | ILE A 191PRO A 162ILE A 168LEU A 172ILE A 184 | None | 0.93A | 4dtaA-5v1sA:undetectable | 4dtaA-5v1sA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb1 | ENVELOPE PROTEINUS28, NANOBODY 7FUSION PROTEIN (Humanbetaherpesvirus5;Lama glama) |
no annotation | 5 | ALA A 132ILE A 133ILE A 226LEU A 230ILE A1101 | None | 1.31A | 4dtaA-5wb1A:undetectable | 4dtaA-5wb1A:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | ALA A 668ILE A 678ILE A 680LEU A1258ILE A 676 | None | 1.02A | 4dtaA-5xsyA:undetectable | 4dtaA-5xsyA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xuo | POLYKETIDE SYNTHASEPKS13 (Mycobacteriumtuberculosis) |
no annotation | 5 | ALA A 806ILE A 781ILE A 741HIS A 723ILE A 779 | None | 1.15A | 4dtaA-5xuoA:undetectable | 4dtaA-5xuoA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b8d | ELONGATION FACTOR G (Haemophilusinfluenzae) |
no annotation | 5 | ALA A 281ILE A 248LEU A 222ILE A 186ASP A 184 | None | 1.29A | 4dtaA-6b8dA:undetectable | 4dtaA-6b8dA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c8v | COENZYME PQQSYNTHESIS PROTEIN E (Methylobacteriumextorquens) |
no annotation | 5 | ILE A 219ILE A 233LEU A 188ILE A 177ASP A 178 | None | 1.30A | 4dtaA-6c8vA:undetectable | 4dtaA-6c8vA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 7 | ALA A 216ILE A 224LYS A 226PRO A 258ILE A 277HIS A 379ILE A 392 | GNP A 500 ( 3.9A)GNP A 500 (-3.7A)GNP A 500 (-2.7A)NoneGNP A 500 (-3.8A) MG A 700 ( 3.2A)GNP A 500 (-3.9A) | 0.57A | 4dtaA-6ceyA:30.7 | 4dtaA-6ceyA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 7 | ALA A 216ILE A 224PRO A 258ILE A 277HIS A 379LEU A 381ILE A 392 | GNP A 500 ( 3.9A)GNP A 500 (-3.7A)NoneGNP A 500 (-3.8A) MG A 700 ( 3.2A)NoneGNP A 500 (-3.9A) | 0.62A | 4dtaA-6ceyA:30.7 | 4dtaA-6ceyA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 5 | ALA A 216LYS A 226PRO A 258HIS A 379ASP A 393 | GNP A 500 ( 3.9A)GNP A 500 (-2.7A)None MG A 700 ( 3.2A) MG A 702 (-1.7A) | 1.00A | 4dtaA-6ceyA:30.7 | 4dtaA-6ceyA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT CMONOVALENT CATION/H+ANTIPORTER SUBUNIT D (Pyrococcusfuriosus) |
no annotation | 5 | ALA H 241LYS H 168ILE H 167HIS G 103ILE H 163 | None | 1.25A | 4dtaA-6cfwH:undetectable | 4dtaA-6cfwH:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6geb | DOTB (Legionellapneumophila) |
no annotation | 5 | ALA A 28ILE A 36ILE A 120LEU A 68ILE A 38 | None | 1.26A | 4dtaA-6gebA:undetectable | 4dtaA-6gebA:14.08 |