SIMILAR PATTERNS OF AMINO ACIDS FOR 4DT8_B_ADNB401
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aj8 | CITRATE SYNTHASE (Pyrococcusfuriosus) |
PF00285(Citrate_synt) | 5 | GLY A 125ILE A 338ILE A 215LEU A 212ILE A 102 | None | 1.01A | 4dt8B-1aj8A:undetectable | 4dt8B-1aj8A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ci9 | PROTEIN(CARBOXYLESTERASE) (Burkholderiagladioli) |
PF00144(Beta-lactamase) | 5 | SER A 272GLY A 274ALA A 275ILE A 148LEU A 166 | NoneNoneDFP A 401 (-3.2A)NoneNone | 1.05A | 4dt8B-1ci9A:undetectable | 4dt8B-1ci9A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | SER A 367ALA A 363ILE A 274ILE A 231LEU A 400 | None | 1.07A | 4dt8B-1g8kA:undetectable | 4dt8B-1g8kA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ldi | GLYCEROL UPTAKEFACILITATOR PROTEIN (Escherichiacoli) |
PF00230(MIP) | 5 | GLY A 51ALA A 55ILE A 56ILE A 163LEU A 159 | None | 1.09A | 4dt8B-1ldiA:undetectable | 4dt8B-1ldiA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nw1 | CHOLINE KINASE (49.2KD) (Caenorhabditiselegans) |
PF01633(Choline_kinase) | 5 | GLY A 84PRO A 139ILE A 154LEU A 262ILE A 300 | None | 1.08A | 4dt8B-1nw1A:14.2 | 4dt8B-1nw1A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | GLY A 173ALA A 174ILE A 6PRO A 143ILE A 133 | None | 0.97A | 4dt8B-1oh9A:undetectable | 4dt8B-1oh9A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pe9 | PECTATE LYASE A (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 5 | SER A 193GLY A 151ALA A 152ILE A 148ILE A 106 | None | 1.06A | 4dt8B-1pe9A:undetectable | 4dt8B-1pe9A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pmj | BETA-1,4-MANNANASE (Caldicellulosiruptorsaccharolyticus) |
PF09212(CBM27) | 5 | GLY X 127ALA X 126ILE X 122ILE X 173ILE X 91 | EDO X 401 (-3.4A)EDO X 401 ( 4.2A)NoneNoneNone | 1.05A | 4dt8B-1pmjX:undetectable | 4dt8B-1pmjX:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1puj | CONSERVEDHYPOTHETICAL PROTEINYLQF (Bacillussubtilis) |
PF01926(MMR_HSR1) | 5 | SER A 100ALA A 99ILE A 54LEU A 136ILE A 85 | None | 1.06A | 4dt8B-1pujA:undetectable | 4dt8B-1pujA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pwe | L-SERINE DEHYDRATASE (Rattusnorvegicus) |
PF00291(PALP) | 5 | ALA A 315PRO A 268ILE A 255LEU A 265ILE A 308 | None | 1.04A | 4dt8B-1pweA:undetectable | 4dt8B-1pweA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qlb | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Wolinellasuccinogenes) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | SER A 390ALA A 394ILE A 375LEU A 184ILE A 239 | None | 1.06A | 4dt8B-1qlbA:undetectable | 4dt8B-1qlbA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlm | PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 5 | ALA A 236PRO A 159ILE A 162ILE A 158ASP A 155 | None | 1.07A | 4dt8B-1rlmA:undetectable | 4dt8B-1rlmA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 5 | ALA A 191ILE A 173LEU A 155ILE A 168ASP A 166 | None | 1.02A | 4dt8B-1s4dA:undetectable | 4dt8B-1s4dA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3d | SERINEACETYLTRANSFERASE (Escherichiacoli) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | GLY A 165ALA A 168ILE A 154LEU A 156ILE A 176 | None | 1.02A | 4dt8B-1t3dA:undetectable | 4dt8B-1t3dA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1un9 | DIHYDROXYACETONEKINASE (Citrobacterfreundii) |
PF02733(Dak1)PF02734(Dak2) | 5 | ALA A 153ILE A 156PRO A 328LEU A 318ILE A 289 | None | 1.07A | 4dt8B-1un9A:undetectable | 4dt8B-1un9A:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6c | ALKALINE SERINEPROTEASE (Pseudoalteromonassp. AS-11) |
PF00082(Peptidase_S8)PF02225(PA) | 5 | GLY A 305ALA A 303ILE A 292LEU A 322ILE A 329 | None | 1.06A | 4dt8B-1v6cA:undetectable | 4dt8B-1v6cA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwp | 5-AMINOLEVULINATESYNTHASE (Rhodobactercapsulatus) |
PF00155(Aminotran_1_2) | 5 | GLY A 208ALA A 204ILE A 182ILE A 135LEU A 133 | None | 1.10A | 4dt8B-2bwpA:undetectable | 4dt8B-2bwpA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c6x | CITRATE SYNTHASE 1 (Bacillussubtilis) |
PF00285(Citrate_synt) | 5 | GLY A 335ALA A 338ILE A 16ILE A 27LEU A 26 | None | 1.09A | 4dt8B-2c6xA:undetectable | 4dt8B-2c6xA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hx1 | PREDICTED SUGARPHOSPHATASES OF THEHAD SUPERFAMILY (Cytophagahutchinsonii) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | SER A 82GLY A 83ALA A 55ILE A 199ILE A 164 | None | 1.10A | 4dt8B-2hx1A:undetectable | 4dt8B-2hx1A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2obm | ESCN (Escherichiacoli) |
PF00006(ATP-synt_ab) | 5 | GLY A 193ALA A 194ILE A 343ILE A 161ASP A 162 | None | 1.00A | 4dt8B-2obmA:undetectable | 4dt8B-2obmA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjs | UNCHARACTERIZEDPROTEIN ATU1953 (Agrobacteriumfabrum) |
PF00903(Glyoxalase) | 5 | GLY A 83ALA A 82ILE A 25ILE A 112LEU A 100 | None | 1.08A | 4dt8B-2pjsA:undetectable | 4dt8B-2pjsA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ps2 | PUTATIVE MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Aspergillusoryzae) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLY A 279ALA A 273LYS A 272ILE A 257ILE A 266 | None | 1.10A | 4dt8B-2ps2A:undetectable | 4dt8B-2ps2A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q1d | 2-KETO-3-DEOXY-D-ARABINONATE DEHYDRATASE (Sulfolobussolfataricus) |
PF01557(FAA_hydrolase) | 5 | ALA X 147ILE X 251PRO X 70LEU X 34ILE X 194 | None | 1.05A | 4dt8B-2q1dX:undetectable | 4dt8B-2q1dX:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q83 | YTAA PROTEIN (Bacillussubtilis) |
PF01636(APH) | 5 | LYS A 72PRO A 99ILE A 124LEU A 246ILE A 256 | NoneADN A 1 ( 4.9A)ADN A 1 (-4.6A)NoneADN A 1 ( 4.6A) | 0.87A | 4dt8B-2q83A:14.4 | 4dt8B-2q83A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qi2 | CELL DIVISIONPROTEIN PELOTARELATED PROTEIN (Thermoplasmaacidophilum) |
PF03463(eRF1_1)PF03465(eRF1_3) | 5 | GLY A 329ILE A 286ILE A 311LEU A 301ILE A 313 | None | 1.10A | 4dt8B-2qi2A:undetectable | 4dt8B-2qi2A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qip | PROTEIN OF UNKNOWNFUNCTION VPA0982 (Vibrioparahaemolyticus) |
PF01936(NYN) | 5 | ALA A 10ILE A 102ILE A 100LEU A 121ILE A 125 | None | 1.01A | 4dt8B-2qipA:undetectable | 4dt8B-2qipA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | GLY A1277ALA A1280ILE A1284ILE A1215ASP A1212 | None | 1.01A | 4dt8B-2vdcA:undetectable | 4dt8B-2vdcA:12.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vr2 | DIHYDROPYRIMIDINASE (Homo sapiens) |
PF01979(Amidohydro_1) | 5 | GLY A 444ALA A 401ILE A 405LEU A 52ILE A 9 | None | 1.09A | 4dt8B-2vr2A:undetectable | 4dt8B-2vr2A:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wwd | 1,4-BETA-N-ACETYLMURAMIDASE (Streptococcuspneumoniae) |
PF01183(Glyco_hydro_25)PF01473(CW_binding_1) | 5 | GLY A 398ALA A 397ILE A 346LEU A 356ILE A 360 | None | 1.04A | 4dt8B-2wwdA:undetectable | 4dt8B-2wwdA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2n | VIRGINIAMYCIN BLYASE (Staphylococcusaureus) |
no annotation | 5 | SER A 183GLY A 184ILE A 178ILE A 209ILE A 164 | None | 1.07A | 4dt8B-2z2nA:undetectable | 4dt8B-2z2nA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zl3 | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Helicobacterpylori) |
PF00574(CLP_protease) | 5 | SER A 67GLY A 35ILE A 37LEU A 63ILE A 45 | None | 1.09A | 4dt8B-2zl3A:undetectable | 4dt8B-2zl3A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afg | SUBTILISIN-LIKESERINE PROTEASE (Thermococcuskodakarensis) |
PF00082(Peptidase_S8)PF04151(PPC) | 5 | SER A 515ALA A 445ILE A 442PRO A 468LEU A 465 | None | 0.94A | 4dt8B-3afgA:undetectable | 4dt8B-3afgA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e18 | OXIDOREDUCTASE (Listeriainnocua) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 335ILE A 336ILE A 224LEU A 183ILE A 214 | None | 1.11A | 4dt8B-3e18A:undetectable | 4dt8B-3e18A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gvd | SERINEACETYLTRANSFERASE (Yersinia pestis) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | GLY A 165ALA A 168ILE A 154LEU A 156ILE A 176 | CYS A 501 ( 4.5A)NoneNoneNoneNone | 1.10A | 4dt8B-3gvdA:undetectable | 4dt8B-3gvdA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5q | PYRIMIDINE-NUCLEOSIDE PHOSPHORYLASE (Staphylococcusaureus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 5 | GLY A 362ALA A 363ILE A 354LEU A 411ILE A 378 | None | 0.89A | 4dt8B-3h5qA:undetectable | 4dt8B-3h5qA:22.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ham | AMINOGLYCOSIDEPHOSPHOTRANSFERASE (Enterococcusfaecium) |
PF01636(APH) | 5 | LYS A 42PRO A 73ILE A 88ILE A 209ASP A 210 | None | 0.43A | 4dt8B-3hamA:32.6 | 4dt8B-3hamA:34.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwj | PUTATIVEAMINOALDEHYDEDEHYDROGENASE (Pisum sativum) |
PF00171(Aldedh) | 5 | GLY A 372PRO A 397ILE A 345LEU A 346ILE A 375 | None | 0.97A | 4dt8B-3iwjA:undetectable | 4dt8B-3iwjA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7a | 40S RIBOSOMALPROTEIN ES2140S RIBOSOMALPROTEIN US2 (Plasmodiumfalciparum) |
PF00318(Ribosomal_S2)PF01249(Ribosomal_S21e) | 5 | GLY Z 37ALA C 66PRO C 142LEU Z 68ILE Z 34 | None | 0.82A | 4dt8B-3j7aZ:undetectable | 4dt8B-3j7aZ:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lly | AGGLUTININ ALPHACHAIN (Maclurapomifera) |
PF01419(Jacalin) | 5 | GLY A 118ILE A 120ILE A 25LEU A 84ILE A 81 | None | 1.07A | 4dt8B-3llyA:undetectable | 4dt8B-3llyA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm5 | SERINE/THREONINE-PROTEIN KINASE 17B (Homo sapiens) |
PF00069(Pkinase) | 5 | GLY A 222ALA A 225ILE A 139ILE A 175ILE A 118 | None | 1.11A | 4dt8B-3lm5A:5.5 | 4dt8B-3lm5A:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lou | FORMYLTETRAHYDROFOLATE DEFORMYLASE (Burkholderiamallei) |
PF00551(Formyl_trans_N) | 5 | SER A 169ALA A 171ILE A 127LEU A 143ILE A 124 | None | 1.11A | 4dt8B-3louA:undetectable | 4dt8B-3louA:21.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n4t | APH(2'')-ID (Enterococcuscasseliflavus) |
PF01636(APH) | 10 | SER A 28GLY A 29ALA A 36ILE A 44LYS A 46PRO A 76ILE A 98LEU A 204ILE A 216ASP A 217 | None | 0.68A | 4dt8B-3n4tA:42.5 | 4dt8B-3n4tA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nd0 | SLL0855 PROTEIN (Synechocystissp. PCC 6803) |
PF00654(Voltage_CLC) | 5 | GLY A 151ILE A 108PRO A 201LEU A 194ILE A 195 | None | 1.10A | 4dt8B-3nd0A:undetectable | 4dt8B-3nd0A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nxk | CYTOPLASMICL-ASPARAGINASE (Campylobacterjejuni) |
PF00710(Asparaginase) | 5 | ALA A 59ILE A 58ILE A 78LEU A 105ILE A 91 | None | 1.00A | 4dt8B-3nxkA:undetectable | 4dt8B-3nxkA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzg | PUTATIVE RACEMASE (Pseudovibriosp. JE062) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLY A 103ALA A 106ILE A 71LEU A 68ILE A 61 | None | 1.03A | 4dt8B-3nzgA:undetectable | 4dt8B-3nzgA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqz | PUTATIVEUNCHARACTERIZEDPROTEIN YJIK (Escherichiacoli) |
PF06977(SdiA-regulated) | 5 | GLY A 219ILE A 178PRO A 181ILE A 180ILE A 228 | None | 1.06A | 4dt8B-3qqzA:undetectable | 4dt8B-3qqzA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qwb | PROBABLE QUINONEOXIDOREDUCTASE (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 129PRO A 110ILE A 277LEU A 273ILE A 94 | NoneNoneNoneNDP A 335 (-4.8A)None | 1.03A | 4dt8B-3qwbA:undetectable | 4dt8B-3qwbA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdw | GENTAMICINRESISTANCE PROTEIN (Enterococcusgallinarum) |
PF01636(APH) | 5 | GLY A 28ALA A 35PRO A 75LEU A 203ILE A 217 | GDP A 500 (-3.4A)GDP A 500 (-3.6A)NoneNoneGDP A 500 ( 4.1A) | 0.37A | 4dt8B-3tdwA:29.9 | 4dt8B-3tdwA:29.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wb1 | UNCHARACTERIZEDPROTEIN MJ0488 (Methanocaldococcusjannaschii) |
PF11576(DUF3236) | 5 | ALA A 64ILE A 66ILE A 54LEU A 147ILE A 100 | None | 0.93A | 4dt8B-3wb1A:undetectable | 4dt8B-3wb1A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zw6 | RIBULOSEBISPHOSPHATECARBOXYLASE/OXYGENASE ACTIVASE 1,CHLOROPLASTIC (Nicotianatabacum) |
PF00004(AAA) | 5 | GLY A 128PRO A 224ILE A 226LEU A 86ILE A 90 | None | 0.90A | 4dt8B-3zw6A:undetectable | 4dt8B-3zw6A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c5f | MEMBRANE-BOUND LYTICMUREINTRANSGLYCOSYLASE C (Escherichiacoli) |
PF01464(SLT)PF11873(DUF3393) | 5 | SER A 152GLY A 149ALA A 151ILE A 104ILE A 127 | None | 1.00A | 4dt8B-4c5fA:undetectable | 4dt8B-4c5fA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cn8 | PROXIMAL THREADMATRIX PROTEIN 1 (Mytilusgalloprovincialis) |
PF00092(VWA) | 5 | GLY A 204PRO A 182ILE A 213LEU A 170ILE A 141 | None | 0.82A | 4dt8B-4cn8A:undetectable | 4dt8B-4cn8A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4da5 | CHOLINE KINASE ALPHA (Homo sapiens) |
PF01633(Choline_kinase) | 5 | PRO A 194ILE A 209LEU A 313ILE A 329ASP A 330 | None | 1.04A | 4dt8B-4da5A:15.8 | 4dt8B-4da5A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gji | L-RHAMNOSE ISOMERASE (Pseudomonasstutzeri) |
no annotation | 5 | SER A 409GLY A 410ILE A 88ILE A 336ASP A 334 | None | 1.03A | 4dt8B-4gjiA:undetectable | 4dt8B-4gjiA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3w | HYPOTHETICAL PROTEIN (Parabacteroidesdistasonis) |
PF15414(DUF4621) | 5 | GLY A 76ILE A 99ILE A 138LEU A 136ILE A 121 | None | 0.98A | 4dt8B-4h3wA:undetectable | 4dt8B-4h3wA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7o | SERINEACETYLTRANSFERASE (Vibrio cholerae) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | GLY A 165ALA A 168ILE A 154LEU A 156ILE A 176 | CYS A 301 ( 4.6A)NoneNoneNoneNone | 1.00A | 4dt8B-4h7oA:undetectable | 4dt8B-4h7oA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifd | EXOSOME COMPLEXCOMPONENT RRP43 (Saccharomycescerevisiae) |
PF01138(RNase_PH) | 5 | GLY C 364ILE C 299ILE C 331LEU C 334ILE C 343 | None | 0.99A | 4dt8B-4ifdC:undetectable | 4dt8B-4ifdC:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jq9 | DIHYDROLIPOYLDEHYDROGENASE (Escherichiacoli) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | GLY A 18ALA A 17ILE A 311ILE A 295ILE A 314 | NoneFAD A 512 (-3.4A)NoneNoneNone | 1.05A | 4dt8B-4jq9A:undetectable | 4dt8B-4jq9A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpr | THIOREDOXINREDUCTASE 1,CYTOPLASMIC (Rattusnorvegicus) |
no annotation | 5 | GLY E 23ALA E 160ILE E 17LEU E 120ASP E 42 | FAD E 505 (-3.6A)FAD E 505 (-4.6A)NoneNoneFAD E 505 (-2.7A) | 1.11A | 4dt8B-4kprE:undetectable | 4dt8B-4kprE:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kwg | ALDEHYDEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF00171(Aldedh) | 5 | GLY A 378PRO A 403ILE A 353LEU A 354ILE A 381 | None | 1.02A | 4dt8B-4kwgA:undetectable | 4dt8B-4kwgA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lqz | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF16253(DUF4909) | 5 | ALA A 65ILE A 83ILE A 38LEU A 154ILE A 48 | None | 1.11A | 4dt8B-4lqzA:undetectable | 4dt8B-4lqzA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lrj | EFFECTOR NLEH1 (Escherichiacoli) |
no annotation | 5 | GLY A 140LYS A 159ILE A 204LEU A 246ILE A 257 | ANP A 301 ( 3.9A)ANP A 301 (-3.6A)ANP A 301 (-4.3A)NoneANP A 301 (-4.2A) | 0.87A | 4dt8B-4lrjA:7.8 | 4dt8B-4lrjA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4na3 | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 6 | GLY A 201ALA A 200ILE A 183ILE A 442LEU A 374ILE A 9 | None | 1.10A | 4dt8B-4na3A:undetectable | 4dt8B-4na3A:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ohq | TRIOSEPHOSPHATEISOMERASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00121(TIM) | 5 | SER A 63GLY A 64ILE A 125ILE A 161LEU A 118 | None | 1.01A | 4dt8B-4ohqA:undetectable | 4dt8B-4ohqA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | SER A 569ALA A 520ILE A 621ILE A 640ILE A 472 | None | 1.04A | 4dt8B-4om9A:undetectable | 4dt8B-4om9A:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4om9 | SERINE PROTEASE PET (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | SER A 569ILE A 621ILE A 640ILE A 472ASP A 499 | None | 1.03A | 4dt8B-4om9A:undetectable | 4dt8B-4om9A:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tkt | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | GLY A3345ALA A3344ILE A3327LEU A3509ILE A3145 | None | 1.03A | 4dt8B-4tktA:undetectable | 4dt8B-4tktA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ALA A 320ILE A 266ILE A 362LEU A 341ILE A 349 | None | 1.10A | 4dt8B-4tr6A:undetectable | 4dt8B-4tr6A:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7d | ATP-DEPENDENT DNAHELICASE Q1 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF16124(RecQ_Zn_bind) | 5 | GLY A 573ALA A 576ILE A 497ILE A 499LEU A 515 | None | 1.08A | 4dt8B-4u7dA:undetectable | 4dt8B-4u7dA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8g | PUTATIVEUNCHARACTERIZEDPROTEIN GBS1891 (Streptococcusagalactiae) |
PF13561(adh_short_C2) | 5 | GLY A 21ALA A 22ILE A 19ILE A 146ILE A 148 | None | 1.09A | 4dt8B-4u8gA:undetectable | 4dt8B-4u8gA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4up3 | THIOREDOXINREDUCTASE (Entamoebahistolytica) |
PF07992(Pyr_redox_2) | 5 | SER A 299GLY A 300ALA A 15ILE A 267ILE A 115 | NoneNoneFAD A1315 (-3.3A)NoneNone | 0.97A | 4dt8B-4up3A:undetectable | 4dt8B-4up3A:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5w | RIBULOSEBISPHOSPHATECARBOXYLASE/OXYGENASE ACTIVASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00004(AAA) | 5 | GLY A 125PRO A 221ILE A 223LEU A 83ILE A 87 | None | 0.91A | 4dt8B-4w5wA:undetectable | 4dt8B-4w5wA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7v | CELLULASE (Xanthomonascitri) |
PF00150(Cellulase) | 5 | GLY A 108ALA A 107ILE A 100PRO A 135LEU A 89 | None | 1.09A | 4dt8B-4w7vA:undetectable | 4dt8B-4w7vA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wh3 | N-ACETYLHEXOSAMINE1-KINASE (Bifidobacteriumlongum) |
PF01636(APH) | 5 | GLY A 28ILE A 46ILE A 105LEU A 215ILE A 227 | ATP A 401 (-3.3A)ATP A 401 (-4.1A)ATP A 401 (-3.9A)GOL A 404 ( 4.7A)ATP A 401 (-4.1A) | 0.87A | 4dt8B-4wh3A:16.4 | 4dt8B-4wh3A:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr2 | PYRIMIDINE-SPECIFICRIBONUCLEOSIDEHYDROLASE RIHA (Shewanellaloihica) |
PF01156(IU_nuc_hydro) | 5 | GLY A 112ALA A 150ILE A 151ILE A 180ILE A 176 | None | 1.02A | 4dt8B-4wr2A:undetectable | 4dt8B-4wr2A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzw | AGAP004976-PA (Anophelesgambiae) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | GLY A 376ILE A 362ILE A 335LEU A 332ILE A 425 | None | 1.10A | 4dt8B-4yzwA:undetectable | 4dt8B-4yzwA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z37 | PUTATIVE MIXEDPOLYKETIDESYNTHASE/NON-RIBOSOMAL PEPTIDESYNTHETASE (Brevibacillusbrevis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 6 | GLY A2521ALA A2520ILE A2503ILE A2756LEU A2685ILE A2325 | None | 1.15A | 4dt8B-4z37A:undetectable | 4dt8B-4z37A:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoq | INTRACELLULAR SERINEPROTEASE (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 5 | GLY I 274ALA I 273ILE I 321ILE I 425ILE I 311 | None | 1.10A | 4dt8B-4zoqI:undetectable | 4dt8B-4zoqI:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5abm | RETINALDEHYDROGENASE 1 (Ovis aries) |
PF00171(Aldedh) | 5 | GLY A 378PRO A 403ILE A 353LEU A 354ILE A 381 | None | 0.95A | 4dt8B-5abmA:undetectable | 4dt8B-5abmA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b69 | GERANYLGERANYLGLYCERYL PHOSPHATESYNTHASE (Thermoplasmaacidophilum) |
PF01884(PcrB) | 5 | GLY A 224ALA A 227ILE A 35ILE A 67ILE A 47 | 1GP A 501 (-3.4A)NoneNoneNoneNone | 0.86A | 4dt8B-5b69A:undetectable | 4dt8B-5b69A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dkv | ABC TRANSPORTERSUBSTRATE BINDINGPROTEIN (RIBOSE) (Agrobacteriumvitis) |
PF13407(Peripla_BP_4) | 5 | GLY A 288ALA A 292ILE A 35PRO A 90ILE A 66 | None | 1.01A | 4dt8B-5dkvA:undetectable | 4dt8B-5dkvA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7s | LON PROTEASE (Meiothermustaiwanensis) |
PF05362(Lon_C) | 5 | ALA A 502ILE A 527ILE A 574LEU A 578ILE A 550 | None | 1.04A | 4dt8B-5e7sA:undetectable | 4dt8B-5e7sA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5erb | POLYKETIDE SYNTHASE (Bacillusamyloliquefaciens) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 6 | GLY A 208ALA A 207ILE A 190ILE A 443LEU A 372ILE A 11 | None | 1.14A | 4dt8B-5erbA:undetectable | 4dt8B-5erbA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5evj | ARSENITEMETHYLTRANSFERASE (Chlamydomonasreinhardtii) |
PF13847(Methyltransf_31) | 5 | GLY A 113ALA A 92PRO A 77ILE A 78ILE A 167 | None | 0.95A | 4dt8B-5evjA:undetectable | 4dt8B-5evjA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fhz | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 (Homo sapiens) |
PF00171(Aldedh) | 5 | GLY A 390PRO A 415ILE A 365LEU A 366ILE A 393 | None | 1.11A | 4dt8B-5fhzA:undetectable | 4dt8B-5fhzA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmg | PROTEASOME SUBUNITBETA TYPE (Plasmodiumfalciparum) |
PF00227(Proteasome) | 5 | GLY N 53ILE N 23ILE N 206LEU N 210ILE N 13 | None | 1.10A | 4dt8B-5fmgN:undetectable | 4dt8B-5fmgN:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gkm | AT5G51070/K3K7_27 (Arabidopsisthaliana) |
PF02861(Clp_N) | 5 | GLY A 114ALA A 117ILE A 132LEU A 215ILE A 130 | None | 0.98A | 4dt8B-5gkmA:undetectable | 4dt8B-5gkmA:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1y | PROBABLEATP-DEPENDENT RNAHELICASE DDX41 (Homo sapiens) |
PF00270(DEAD) | 5 | GLY A 223ALA A 225ILE A 207ILE A 209ILE A 169 | None | 0.94A | 4dt8B-5h1yA:undetectable | 4dt8B-5h1yA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h78 | CAMP-DEPENDENTPROTEIN KINASE TYPEII-ALPHA REGULATORYSUBUNIT,DHR14 (Homo sapiens;syntheticconstruct) |
PF02197(RIIa) | 5 | ALA A 132ILE A 147ILE A 145LEU A 183ILE A 187 | None | 1.04A | 4dt8B-5h78A:undetectable | 4dt8B-5h78A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jgp | NITRATE/NITRITESENSOR PROTEIN NARQ (Escherichiacoli) |
PF00672(HAMP)PF13675(PilJ) | 5 | SER A 80ALA A 77ILE A 45ILE A 43LEU A 139 | None | 1.00A | 4dt8B-5jgpA:2.3 | 4dt8B-5jgpA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nek | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
no annotation | 5 | GLY A 78PRO A 160ILE A 156ILE A 152ASP A 148 | None | 1.08A | 4dt8B-5nekA:undetectable | 4dt8B-5nekA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1s | RADICAL SAM (Streptococcussuis) |
PF04055(Radical_SAM)PF13394(Fer4_14) | 5 | ILE A 191PRO A 162ILE A 168LEU A 172ILE A 184 | None | 0.72A | 4dt8B-5v1sA:undetectable | 4dt8B-5v1sA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCE (Pseudomonasaeruginosa) |
PF06833(MdcE) | 5 | GLY A 232ALA A 234ILE A 133ILE A 94LEU A 16 | None | 1.06A | 4dt8B-5vipA:undetectable | 4dt8B-5vipA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | ALA A 668ILE A 678ILE A 680LEU A1258ILE A 676 | None | 1.06A | 4dt8B-5xsyA:undetectable | 4dt8B-5xsyA:10.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zbi | PEPTIDE ASPARAGINYLLIGASE (Violacanadensis) |
no annotation | 5 | SER A 459GLY A 456ALA A 458ILE A 385ILE A 445 | None | 0.97A | 4dt8B-5zbiA:undetectable | 4dt8B-5zbiA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvt | C-TERMINUS OF OUTERCAPSID PROTEIN VP5 (Aquareovirus C) |
no annotation | 5 | SER B 500ALA B 304ILE B 299LEU B 464ILE B 339 | None | 1.06A | 4dt8B-5zvtB:undetectable | 4dt8B-5zvtB:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b5i | RETINALDEHYDROGENASE 2 (Homo sapiens) |
no annotation | 5 | GLY A 396PRO A 421ILE A 371LEU A 372ILE A 399 | None | 0.92A | 4dt8B-6b5iA:undetectable | 4dt8B-6b5iA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 6 | GLY A 209ALA A 216ILE A 224LYS A 226PRO A 258ASP A 393 | GNP A 500 ( 4.3A)GNP A 500 ( 3.9A)GNP A 500 (-3.7A)GNP A 500 (-2.7A)None MG A 702 (-1.7A) | 0.89A | 4dt8B-6ceyA:30.6 | 4dt8B-6ceyA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 7 | GLY A 209ALA A 216ILE A 224LYS A 226PRO A 258ILE A 277ILE A 392 | GNP A 500 ( 4.3A)GNP A 500 ( 3.9A)GNP A 500 (-3.7A)GNP A 500 (-2.7A)NoneGNP A 500 (-3.8A)GNP A 500 (-3.9A) | 0.61A | 4dt8B-6ceyA:30.6 | 4dt8B-6ceyA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 7 | GLY A 209ALA A 216ILE A 224PRO A 258ILE A 277LEU A 381ILE A 392 | GNP A 500 ( 4.3A)GNP A 500 ( 3.9A)GNP A 500 (-3.7A)NoneGNP A 500 (-3.8A)NoneGNP A 500 (-3.9A) | 0.66A | 4dt8B-6ceyA:30.6 | 4dt8B-6ceyA:14.38 |