SIMILAR PATTERNS OF AMINO ACIDS FOR 4DO3_B_0LAB602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 LEU B1770
LEU B1774
ILE B1752
THR B1783
 CYG  B1769 ( 4.1A)
None
None
None
 0.65A 4do3B-1a9xB:
2.3		 4do3B-1a9xB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		5 LEU A 195
LEU A  64
ILE A 105
MET A 301
THR A  82
 None
 1.28A 4do3B-1ayeA:
0.0		 4do3B-1ayeA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		5 LEU A 551
LEU A 419
ILE A 460
MET A 657
THR A 437
 None
 1.28A 4do3B-1dtdA:
undetectable		 4do3B-1dtdA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fzq ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
3

(Mus musculus) 		PF00025
(Arf) 		4 LEU A 110
LEU A  88
ILE A  89
THR A  85
 None
 0.96A 4do3B-1fzqA:
0.0		 4do3B-1fzqA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1har HIV-1 REVERSE
TRANSCRIPTASE
(FINGERS AND PALM
SUBDOMAINS)

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1) 		4 LEU A 168
LEU A 205
ILE A 202
THR A 216
 None
 0.90A 4do3B-1harA:
0.9		 4do3B-1harA:
17.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mt5 FATTY-ACID AMIDE
HYDROLASE

(Rattus
norvegicus) 		PF01425
(Amidase) 		6 LEU A 192
LEU A 404
ILE A 407
MET A 436
THR A 488
TRP A 531
 MAY  A 600 ( 4.2A)
None
None
None
MAY  A 600 ( 4.2A)
None
 0.80A 4do3B-1mt5A:
68.3		 4do3B-1mt5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n31 L-CYSTEINE/CYSTINE
LYASE C-DES

(Synechocystis
sp. PCC 6714) 		PF00266
(Aminotran_5) 		4 LEU A 167
LEU A 174
ILE A 179
THR A 140
 None
 0.97A 4do3B-1n31A:
0.0		 4do3B-1n31A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r9j TRANSKETOLASE

(Leishmania
mexicana) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 360
LEU A 370
ILE A 426
TRP A 339
 None
 0.86A 4do3B-1r9jA:
0.0		 4do3B-1r9jA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5j DNA POLYMERASE I

(Sulfolobus
solfataricus) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 LEU A 418
LEU A 310
ILE A 354
MET A 429
 None
 0.96A 4do3B-1s5jA:
undetectable		 4do3B-1s5jA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5c CENTROMERIC PROTEIN
E

(Homo sapiens) 		PF00225
(Kinesin) 		4 LEU A 292
LEU A 296
ILE A 269
THR A 302
 None
 0.94A 4do3B-1t5cA:
undetectable		 4do3B-1t5cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t8w AMP NUCLEOSIDASE

(Escherichia
coli) 		PF01048
(PNP_UDP_1)
PF10423
(AMNp_N) 		4 LEU A 295
LEU A 292
ILE A 288
THR A 274
 None
 1.01A 4do3B-1t8wA:
undetectable		 4do3B-1t8wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz7 4-ALPHA-GLUCANOTRANS
FERASE

(Aquifex
aeolicus) 		PF02446
(Glyco_hydro_77) 		4 LEU A  46
LEU A  70
ILE A  19
THR A  49
 None
 0.93A 4do3B-1tz7A:
undetectable		 4do3B-1tz7A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdc NADPH DEPENDENT
THIOREDOXIN
REDUCTASE

(Arabidopsis
thaliana) 		PF07992
(Pyr_redox_2) 		4 LEU A 252
LEU A 110
ILE A 109
THR A 276
 None
 1.00A 4do3B-1vdcA:
undetectable		 4do3B-1vdcA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 LEU A 548
ILE A 545
MET A 594
THR A 584
 None
 0.81A 4do3B-1wz2A:
undetectable		 4do3B-1wz2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwd FOLLICLE STIMULATING
HORMONE RECEPTOR

(Homo sapiens) 		PF01462
(LRRNT)
PF13306
(LRR_5) 		4 LEU C 233
LEU C 209
ILE C 185
THR C 228
 None
 0.91A 4do3B-1xwdC:
undetectable		 4do3B-1xwdC:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbr CONSERVED
HYPOTHETICAL PROTEIN

(Porphyromonas
gingivalis) 		PF04371
(PAD_porph) 		4 LEU A 145
LEU A 183
ILE A 180
THR A 160
 None
 0.99A 4do3B-1zbrA:
undetectable		 4do3B-1zbrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbr CONSERVED
HYPOTHETICAL PROTEIN

(Porphyromonas
gingivalis) 		PF04371
(PAD_porph) 		4 LEU A 187
LEU A 183
ILE A 179
THR A 160
 None
 0.86A 4do3B-1zbrA:
undetectable		 4do3B-1zbrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1f URIDYLATE KINASE

(Haemophilus
influenzae) 		PF00696
(AA_kinase) 		4 LEU A  52
LEU A  18
ILE A  30
MET A  34
 None
 1.00A 4do3B-2a1fA:
undetectable		 4do3B-2a1fA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkx GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Bacillus
subtilis) 		PF01182
(Glucosamine_iso) 		4 LEU A 232
LEU A 194
ILE A 128
THR A  43
 None
 0.86A 4do3B-2bkxA:
undetectable		 4do3B-2bkxA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6i ATP-DEPENDENT CLP
PROTEASE, PUTATIVE

(Plasmodium
falciparum) 		PF00574
(CLP_protease) 		4 LEU A 270
ILE A 288
MET A 341
THR A 324
 None
 0.98A 4do3B-2f6iA:
undetectable		 4do3B-2f6iA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fl3 R.HINP1I RESTRICTION
ENDONUCLEASE

(Haemophilus
influenzae) 		PF11463
(R-HINP1I) 		4 LEU A 235
LEU A 116
ILE A 115
MET A 138
 None
 0.99A 4do3B-2fl3A:
undetectable		 4do3B-2fl3A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h98 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM

(Acinetobacter
sp. ADP1) 		PF03466
(LysR_substrate) 		4 LEU A 174
LEU A 166
ILE A 242
MET A 192
 None
 1.00A 4do3B-2h98A:
3.7		 4do3B-2h98A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hru PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE II

(Thermotoga
maritima) 		PF00586
(AIRS)
PF02769
(AIRS_C)
PF16904
(PurL_C) 		4 LEU A 402
LEU A 153
ILE A  91
THR A 441
 None
 0.89A 4do3B-2hruA:
undetectable		 4do3B-2hruA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jer AGMATINE DEIMINASE

(Enterococcus
faecalis) 		PF04371
(PAD_porph) 		4 LEU A 198
LEU A 194
ILE A 190
THR A 171
 None
 0.98A 4do3B-2jerA:
undetectable		 4do3B-2jerA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l54 DOUBLE-STRANDED
RNA-SPECIFIC
ADENOSINE DEAMINASE

(Homo sapiens) 		PF02295
(z-alpha) 		4 LEU A  55
LEU A  46
ILE A  42
THR A  26
 None
 0.97A 4do3B-2l54A:
undetectable		 4do3B-2l54A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lse FOUR HELIX BUNDLE
PROTEIN

(synthetic
construct) 		no annotation 4 LEU A  12
LEU A  16
ILE A  31
MET A  58
 None
 1.00A 4do3B-2lseA:
undetectable		 4do3B-2lseA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n2h PAIRED AMPHIPATHIC
HELIX PROTEIN SIN3A

(Mus musculus) 		PF08295
(Sin3_corepress) 		4 LEU B 685
LEU B 670
ILE B 673
THR B 630
 None
 0.78A 4do3B-2n2hB:
undetectable		 4do3B-2n2hB:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvm FDXN ELEMENT
EXCISION CONTROLLING
FACTOR XISI

(Trichormus
variabilis) 		PF08869
(XisI) 		4 LEU A  73
LEU A  75
ILE A  82
MET A  97
 None
 0.98A 4do3B-2nvmA:
undetectable		 4do3B-2nvmA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8d HEMOLYSIN

(Xylella
fastidiosa) 		PF03471
(CorC_HlyC) 		4 LEU A  87
LEU A  28
ILE A  25
MET A  50
 None
 0.97A 4do3B-2r8dA:
undetectable		 4do3B-2r8dA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wy0 ANGIOTENSINOGEN

(Mus musculus) 		PF00079
(Serpin) 		4 LEU C 311
LEU C 348
ILE C 280
MET C 255
 None
 0.97A 4do3B-2wy0C:
undetectable		 4do3B-2wy0C:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzf GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		4 LEU A 196
LEU A 170
ILE A 247
MET A 148
 None
None
UDP  A1525 (-4.6A)
None
 0.95A 4do3B-2wzfA:
undetectable		 4do3B-2wzfA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzg GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		4 LEU A 196
LEU A 170
ILE A 247
MET A 148
 None
None
UPG  A1525 (-4.6A)
None
 0.94A 4do3B-2wzgA:
undetectable		 4do3B-2wzgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoo PROBABLE NITRITE
REDUCTASE

(Pseudoalteromonas
haloplanktis) 		PF00034
(Cytochrom_C)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		4 LEU A 216
LEU A 276
ILE A 275
THR A 200
 None
 0.97A 4do3B-2zooA:
undetectable		 4do3B-2zooA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ax6 PHOSPHORIBOSYLAMINOI
MIDAZOLE
CARBOXYLASE, ATPASE
SUBUNIT

(Thermotoga
maritima) 		PF02222
(ATP-grasp) 		4 LEU A  81
LEU A  78
ILE A  73
THR A  66
 None
 0.95A 4do3B-3ax6A:
undetectable		 4do3B-3ax6A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2d CD180 ANTIGEN

(Homo sapiens) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 LEU A 106
LEU A 130
ILE A 143
MET A 116
 None
 0.97A 4do3B-3b2dA:
undetectable		 4do3B-3b2dA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh6 ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
3

(Mus musculus) 		PF00025
(Arf) 		4 LEU A 110
LEU A  88
ILE A  89
THR A  85
 None
 0.98A 4do3B-3bh6A:
undetectable		 4do3B-3bh6A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5w PP2A-SPECIFIC
METHYLESTERASE PME-1

(Homo sapiens) 		PF12697
(Abhydrolase_6) 		4 LEU P 110
LEU P  80
ILE P 150
THR P 165
 None
 0.92A 4do3B-3c5wP:
undetectable		 4do3B-3c5wP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dmp URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Burkholderia
pseudomallei) 		PF14681
(UPRTase) 		4 LEU A  94
ILE A 130
MET A 162
THR A  51
 None
 0.87A 4do3B-3dmpA:
undetectable		 4do3B-3dmpA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvq FE(3+) IONS IMPORT
ATP-BINDING PROTEIN
FBPC

(Neisseria
gonorrhoeae) 		PF00005
(ABC_tran) 		4 LEU A  33
LEU A  25
ILE A  23
MET A 212
 None
 0.98A 4do3B-3fvqA:
undetectable		 4do3B-3fvqA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5b NETRIN RECEPTOR
UNC5B

(Rattus
norvegicus) 		PF00531
(Death)
PF00791
(ZU5)
PF17217
(UPA) 		4 LEU A 796
LEU A 712
ILE A 699
THR A 826
 None
 0.98A 4do3B-3g5bA:
undetectable		 4do3B-3g5bA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM

(Acinetobacter
sp. ADP1) 		PF03466
(LysR_substrate) 		4 LEU A 174
LEU A 166
ILE A 242
MET A 192
 None
 0.89A 4do3B-3glbA:
4.1		 4do3B-3glbA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz5 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		4 LEU A 176
LEU A 203
ILE A 204
THR A 226
 None
 1.01A 4do3B-3gz5A:
undetectable		 4do3B-3gz5A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B

(Gallus gallus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B) 		4 LEU C 241
LEU C  83
ILE C  80
THR C  44
 None
 1.00A 4do3B-3h1lC:
undetectable		 4do3B-3h1lC:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jys SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 LEU A 229
LEU A 204
ILE A 207
TRP A 199
 None
 0.99A 4do3B-3jysA:
0.0		 4do3B-3jysA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myd FLAGELLAR
BIOSYNTHESIS PROTEIN
FLHA

(Helicobacter
pylori) 		PF00771
(FHIPEP) 		4 LEU A 644
LEU A 667
ILE A 668
MET A 702
 None
 1.00A 4do3B-3mydA:
undetectable		 4do3B-3mydA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nio GUANIDINOBUTYRASE

(Pseudomonas
aeruginosa) 		PF00491
(Arginase) 		4 LEU A 181
LEU A 136
ILE A 135
THR A 171
 None
 0.88A 4do3B-3nioA:
undetectable		 4do3B-3nioA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpw ABC TRANSPORTER

(Rhodopseudomonas
palustris) 		PF13416
(SBP_bac_8) 		4 LEU A 356
LEU A 205
ILE A 208
TRP A 156
 None
 1.00A 4do3B-3rpwA:
2.2		 4do3B-3rpwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3snk RESPONSE REGULATOR
CHEY-LIKE PROTEIN

(Mesorhizobium
loti) 		no annotation 4 LEU A  96
LEU A  72
ILE A  77
MET A 107
 None
 1.00A 4do3B-3snkA:
undetectable		 4do3B-3snkA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		4 LEU A 310
ILE A 316
MET A  61
TRP A  39
 None
 1.00A 4do3B-3ucqA:
undetectable		 4do3B-3ucqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Aliivibrio
fischeri) 		PF00275
(EPSP_synthase) 		4 LEU A 264
LEU A 240
ILE A 250
THR A 255
 None
 0.98A 4do3B-3vcyA:
undetectable		 4do3B-3vcyA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsy SORTILIN-RELATED
RECEPTOR

(Homo sapiens) 		PF15901
(Sortilin_C)
PF15902
(Sortilin-Vps10) 		4 LEU A 644
ILE A 374
THR A 443
TRP A 450
 None
 0.98A 4do3B-3wsyA:
undetectable		 4do3B-3wsyA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwy D-LACTATE
DEHYDROGENASE

(Fusobacterium
nucleatum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 206
LEU A 232
ILE A 255
MET A 223
 None
 0.98A 4do3B-3wwyA:
undetectable		 4do3B-3wwyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		4 LEU A 157
LEU A 106
ILE A 109
MET A 113
 None
 1.00A 4do3B-4a2qA:
undetectable		 4do3B-4a2qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		4 LEU A 157
LEU A 106
ILE A 109
MET A 113
 None
 0.98A 4do3B-4a2wA:
1.4		 4do3B-4a2wA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay9 FOLLICLE-STIMULATING
HORMONE RECEPTOR

(Homo sapiens) 		PF01462
(LRRNT)
PF12369
(GnHR_trans)
PF13306
(LRR_5) 		4 LEU X 233
LEU X 209
ILE X 185
THR X 228
 None
 0.93A 4do3B-4ay9X:
undetectable		 4do3B-4ay9X:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmr GLYCOSYL
HYDROLASE/DEACETYLAS
E FAMILY PROTEIN

(Pyrococcus sp.
ST04) 		no annotation 4 LEU A  67
LEU A  70
ILE A 281
TRP A 270
 None
 0.96A 4do3B-4cmrA:
undetectable		 4do3B-4cmrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		4 LEU A 176
LEU A 138
ILE A 120
MET A 127
 None
 0.89A 4do3B-4e6wA:
undetectable		 4do3B-4e6wA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdw LEUCINE RICH
HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF07523
(Big_3)
PF13306
(LRR_5) 		4 LEU A 222
LEU A 198
ILE A 176
THR A 217
 None
 0.80A 4do3B-4fdwA:
undetectable		 4do3B-4fdwA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fin ETTA (YJJK) ABCF
FAMILY PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran)
PF12848
(ABC_tran_Xtn) 		4 LEU A 230
LEU A  48
ILE A  51
MET A   8
 None
 0.95A 4do3B-4finA:
undetectable		 4do3B-4finA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jw2 A3 ARTIFICIAL
PROTEIN

(synthetic
construct) 		PF13646
(HEAT_2) 		4 LEU A  23
LEU A  50
ILE A  72
TRP A  67
 None
 0.99A 4do3B-4jw2A:
undetectable		 4do3B-4jw2A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1p NHEA

(Bacillus cereus) 		PF05791
(Bacillus_HBL) 		4 LEU A 307
LEU A  21
ILE A  25
MET A  85
 None
 0.95A 4do3B-4k1pA:
undetectable		 4do3B-4k1pA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		4 LEU A 119
LEU A 391
ILE A 394
TRP A 336
 None
 0.87A 4do3B-4lq1A:
undetectable		 4do3B-4lq1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8y PUTATIVE TRAP-TYPE
C4-DICARBOXYLATE
TRANSPORT SYSTEM,
BINDING PERIPLASMIC
PROTEIN (DCTP
SUBUNIT)

(Bradyrhizobium
sp. BTAi1) 		PF03480
(DctP) 		4 LEU A 157
LEU A 160
ILE A 165
THR A 226
 None
 0.98A 4do3B-4n8yA:
2.5		 4do3B-4n8yA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nap EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7

(Desulfovibrio
alaskensis) 		PF03480
(DctP) 		4 LEU A 164
LEU A 167
ILE A 172
THR A 229
 None
 1.00A 4do3B-4napA:
2.0		 4do3B-4napA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oli NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 699
LEU A 695
ILE A 755
THR A 803
 None
 0.97A 4do3B-4oliA:
undetectable		 4do3B-4oliA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pls ARM00010

(synthetic
construct) 		PF00514
(Arm) 		4 LEU A  62
LEU A 100
ILE A 122
TRP A 117
 None
 0.99A 4do3B-4plsA:
undetectable		 4do3B-4plsA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP

(Salmonella
enterica) 		PF12468
(TTSSLRR)
PF14496
(NEL) 		4 LEU A 206
LEU A 204
ILE A 201
MET A 172
 None
 0.98A 4do3B-4pufA:
undetectable		 4do3B-4pufA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA

(Bacillus
subtilis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 LEU A 375
LEU A 373
ILE A 258
THR A 181
 None
 0.85A 4do3B-4tr6A:
undetectable		 4do3B-4tr6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u02 AMINO ACID ABC
TRANSPORTER,
ATP-BINDING PROTEIN

(Thermus
thermophilus) 		PF00005
(ABC_tran) 		4 LEU A  33
LEU A  25
ILE A  23
MET A 211
 None
 0.95A 4do3B-4u02A:
undetectable		 4do3B-4u02A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u6u COG5
COG7

(Kluyveromyces
lactis) 		PF10392
(COG5)
no annotation 		4 LEU A  49
LEU A  30
ILE A  29
THR B 127
 None
 1.00A 4do3B-4u6uA:
undetectable		 4do3B-4u6uA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca) 		PF07993
(NAD_binding_4) 		5 LEU A1495
ILE A1496
MET A1414
THR A1341
TRP A1349
 None
 1.45A 4do3B-4w4tA:
undetectable		 4do3B-4w4tA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wov NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 699
LEU A 695
ILE A 755
THR A 803
 None
 0.95A 4do3B-4wovA:
undetectable		 4do3B-4wovA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyk NUCLEAR RNA EXPORT
FACTOR 1

(Homo sapiens) 		PF02136
(NTF2) 		4 LEU A 270
LEU A 296
ILE A 312
MET A 283
 None
 1.01A 4do3B-4wykA:
undetectable		 4do3B-4wykA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwj PHOSPHOCARRIER
PROTEIN HPR

(Escherichia
coli) 		PF00381
(PTS-HPr) 		4 LEU B  50
LEU B  55
ILE B   8
MET B  81
 None
 0.99A 4do3B-4xwjB:
undetectable		 4do3B-4xwjB:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei) 		PF09818
(ABC_ATPase) 		4 LEU A 326
ILE A 478
MET A 302
THR A 309
 None
 0.96A 4do3B-4yj1A:
undetectable		 4do3B-4yj1A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei) 		PF09818
(ABC_ATPase) 		4 LEU A 326
LEU A 322
ILE A 478
MET A 302
 None
 0.89A 4do3B-4yj1A:
undetectable		 4do3B-4yj1A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zjf GLYCOPROTEIN

(Lassa
mammarenavirus) 		PF00798
(Arena_glycoprot) 		4 LEU A 220
LEU A 105
ILE A  95
THR A 190
 None
 1.00A 4do3B-4zjfA:
undetectable		 4do3B-4zjfA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk3 SERPIN B3

(Homo sapiens) 		PF00079
(Serpin) 		4 LEU A 241
LEU A 382
ILE A  32
THR A 378
 None
 0.89A 4do3B-4zk3A:
undetectable		 4do3B-4zk3A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dcq ARTIFICIAL REPEAT
PROTEINS (ALPHAREP3)

(synthetic
construct) 		PF03130
(HEAT_PBS)
PF13646
(HEAT_2) 		4 LEU A  22
LEU A  49
ILE A  71
TRP A  66
 None
 1.00A 4do3B-5dcqA:
undetectable		 4do3B-5dcqA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ern FUSICOCCADIENE
SYNTHASE

(Diaporthe
amygdali) 		PF00348
(polyprenyl_synt) 		4 LEU A 211
LEU A 207
ILE A 313
THR A 184
 None
 0.95A 4do3B-5ernA:
undetectable		 4do3B-5ernA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f0o COHESIN SUBUNIT
PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P

(Lachancea
thermotolerans) 		no annotation 4 LEU A 429
LEU A 384
ILE A 383
THR A 416
 None
 0.97A 4do3B-5f0oA:
undetectable		 4do3B-5f0oA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fse UREASE SUBUNIT ALPHA

(Sporosarcina
pasteurii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		5 LEU C 508
LEU C 510
ILE C 514
MET C 495
THR C 187
 None
None
EDO  C1576 ( 4.2A)
None
None
 1.50A 4do3B-5fseC:
undetectable		 4do3B-5fseC:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsr D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACD

(Escherichia
coli) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		4 LEU A 233
LEU A  29
ILE A   4
THR A  25
 None
 0.82A 4do3B-5fsrA:
undetectable		 4do3B-5fsrA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 LEU A 585
LEU A 421
ILE A 420
TRP A 400
 None
 0.77A 4do3B-5gjeA:
undetectable		 4do3B-5gjeA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs0 TOLL-LIKE RECEPTOR 3

(Homo sapiens) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 202
LEU A 204
ILE A 209
THR A 162
 None
 0.99A 4do3B-5gs0A:
undetectable		 4do3B-5gs0A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk0 TYROSINE RECOMBINASE
XERH

(Helicobacter
pylori) 		PF00589
(Phage_integrase) 		4 LEU A 288
LEU A 203
ILE A 206
MET A 212
 None
 0.99A 4do3B-5jk0A:
undetectable		 4do3B-5jk0A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksw DIHYDROOROTATE
DEHYDROGENASE B
(NAD(+)), ELECTRON
TRANSFER SUBUNIT

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 LEU B  40
LEU B  42
ILE B  83
MET B  23
 None
 0.92A 4do3B-5kswB:
1.4		 4do3B-5kswB:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l8v DNA REPAIR AND
RECOMBINATION
PROTEIN RADA

(Pyrococcus
furiosus) 		PF08423
(Rad51) 		4 LEU A 261
LEU A 305
ILE A 304
THR A 310
 None
 0.73A 4do3B-5l8vA:
undetectable		 4do3B-5l8vA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lgd PLATELET
GLYCOPROTEIN 4

(Homo sapiens) 		PF01130
(CD36) 		4 LEU A 416
LEU A 387
ILE A 271
THR A 369
 None
PLM  A 513 ( 4.4A)
PLM  A 513 ( 4.6A)
PLM  A 513 (-3.9A)
 0.91A 4do3B-5lgdA:
undetectable		 4do3B-5lgdA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m7r PROTEIN O-GLCNACASE

(Homo sapiens) 		PF07555
(NAGidase) 		4 LEU A 158
LEU A 154
ILE A 143
THR A 199
 None
 0.93A 4do3B-5m7rA:
undetectable		 4do3B-5m7rA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obn RNA-BINDING PROTEIN
40

(Homo sapiens) 		no annotation 4 LEU A 459
LEU A 436
ILE A 439
MET A 496
 None
 0.84A 4do3B-5obnA:
undetectable		 4do3B-5obnA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tv2 ELONGATION FACTOR G

(Vibrio
vulnificus) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 LEU A 103
LEU A 106
ILE A  13
THR A  89
 None
 0.80A 4do3B-5tv2A:
undetectable		 4do3B-5tv2A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhk O-GLCNACASE
TIM-BARREL DOMAIN

(Homo sapiens) 		PF07555
(NAGidase) 		4 LEU A 158
LEU A 154
ILE A 143
THR A 199
 None
 0.98A 4do3B-5uhkA:
undetectable		 4do3B-5uhkA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhp O-GLCNACASE
TIM-BARREL DOMAIN

(Homo sapiens) 		PF07555
(NAGidase) 		4 LEU A 158
LEU A 154
ILE A 143
THR A 199
 None
 0.94A 4do3B-5uhpA:
undetectable		 4do3B-5uhpA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vh6 ELONGATION FACTOR G

(Bacillus
subtilis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 LEU A  96
LEU A  99
ILE A  13
THR A  82
 None
 0.84A 4do3B-5vh6A:
undetectable		 4do3B-5vh6A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vl1 LYSINE--TRNA LIGASE

(Mycobacterium
ulcerans) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 LEU A 190
LEU A 289
ILE A 290
MET A 470
 None
 0.99A 4do3B-5vl1A:
undetectable		 4do3B-5vl1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5win -

(-) 		no annotation 4 LEU A 638
LEU A 634
ILE A 695
THR A 742
 None
 0.95A 4do3B-5winA:
undetectable		 4do3B-5winA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yk2 PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 405
LEU A 343
ILE A 344
THR A 322
 None
 0.95A 4do3B-5yk2A:
undetectable		 4do3B-5yk2A:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aqh LYSINE--TRNA LIGASE

(Mycolicibacterium
thermoresistibile) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 LEU A 193
LEU A 292
ILE A 293
MET A 474
 None
 0.99A 4do3B-6aqhA:
undetectable		 4do3B-6aqhA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 LEU D 141
LEU D 106
ILE D  79
TRP D  49
 None
 0.99A 4do3B-6f45D:
undetectable		 4do3B-6f45D:
undetectable