SIMILAR PATTERNS OF AMINO ACIDS FOR 4D7H_A_H4BA902

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bvl HULYS11

(Homo sapiens;
Mus musculus) 		PF07686
(V-set) 		3 ARG B  96
THR A  57
TRP A  52
 None
 1.25A 4d7hA-1bvlB:
undetectable		 4d7hA-1bvlB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dm9 HYPOTHETICAL 15.5 KD
PROTEIN IN MRCA-PCKA
INTERGENIC REGION

(Escherichia
coli) 		PF01479
(S4) 		3 ARG A  19
THR A  23
TRP A  16
 SO4  A 993 (-2.7A)
None
None
 1.17A 4d7hA-1dm9A:
undetectable		 4d7hA-1dm9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gll GLYCEROL KINASE

(Escherichia
coli) 		no annotation 3 ARG Y 106
THR Y  85
TRP Y 103
 None
None
GOL  Y 600 ( 3.6A)
 1.19A 4d7hA-1gllY:
0.2		 4d7hA-1gllY:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus) 		PF04616
(Glyco_hydro_43) 		3 ARG B  84
THR B  80
TRP B  81
 None
 1.11A 4d7hA-1gydB:
0.0		 4d7hA-1gydB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT
II

(Salmonella
enterica) 		PF00117
(GATase) 		3 ARG B  21
THR B  13
TRP B  14
 None
 1.14A 4d7hA-1i1qB:
0.0		 4d7hA-1i1qB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwg BETA-GALACTOSIDASE

(Thermus
thermophilus) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 ARG A 626
THR A 605
TRP A 606
 None
 0.96A 4d7hA-1kwgA:
1.0		 4d7hA-1kwgA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mir PROCATHEPSIN B

(Rattus
norvegicus) 		PF00112
(Peptidase_C1)
PF08127
(Propeptide_C1) 		3 ARG A  49
THR A 253
TRP A 257
 None
 1.24A 4d7hA-1mirA:
undetectable		 4d7hA-1mirA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Escherichia
coli) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 ARG A  20
THR A 326
TRP A 301
 None
 0.86A 4d7hA-1t4bA:
undetectable		 4d7hA-1t4bA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkc TRANSKETOLASE

(Saccharomyces
cerevisiae) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 ARG A 500
THR A 620
TRP A 623
 None
 1.21A 4d7hA-1tkcA:
0.4		 4d7hA-1tkcA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9n DNA LIGASE I

(Homo sapiens) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		3 ARG A 678
THR A 726
TRP A 742
 None
 1.26A 4d7hA-1x9nA:
undetectable		 4d7hA-1x9nA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc6 BETA-GALACTOSIDASE

(Penicillium sp.) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		3 ARG A 926
THR A 754
TRP A 308
 None
 1.19A 4d7hA-1xc6A:
0.7		 4d7hA-1xc6A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6x ADP-RIBOSYLATION
FACTOR 4

(Homo sapiens) 		PF00025
(Arf) 		3 ARG A 149
THR A 152
TRP A 153
 None
 1.08A 4d7hA-1z6xA:
undetectable		 4d7hA-1z6xA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ab5 MRNA MATURASE

(Saccharomyces
cerevisiae) 		PF00961
(LAGLIDADG_1) 		3 ARG A 336
THR A 279
TRP A 277
 None
 1.00A 4d7hA-2ab5A:
undetectable		 4d7hA-2ab5A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aex COPROPORPHYRINOGEN
III OXIDASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01218
(Coprogen_oxidas) 		3 ARG A 391
THR A 286
TRP A 384
 None
 0.88A 4d7hA-2aexA:
undetectable		 4d7hA-2aexA:
20.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2an2 P332G A333S DOUBLE
MUTANT OF NITRIC
OXIDE SYNTHASE FROM
BACILLUS SUBTILIS

(Bacillus
subtilis) 		PF02898
(NO_synthase) 		3 ARG A 243
THR A 324
TRP A 325
 H4B  A 903 (-3.4A)
None
H4B  A 903 ( 3.6A)
 0.26A 4d7hA-2an2A:
55.4		 4d7hA-2an2A:
93.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpn GLYCEROL KINASE

(Thermus
thermophilus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 ARG A 186
THR A  83
TRP A 101
 None
 1.15A 4d7hA-2dpnA:
undetectable		 4d7hA-2dpnA:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2flq NITRIC OXIDE
SYNTHASE

(Geobacillus
stearothermophilus) 		PF02898
(NO_synthase) 		3 ARG A 252
THR A 333
TRP A 334
 None
 0.16A 4d7hA-2flqA:
46.6		 4d7hA-2flqA:
63.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g02 NISIN BIOSYNTHESIS
PROTEIN NISC

(Lactococcus
lactis) 		PF05147
(LANC_like) 		3 ARG A 345
THR A 399
TRP A 401
 None
 1.16A 4d7hA-2g02A:
undetectable		 4d7hA-2g02A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT
ETHYLBENZENE
DEHYDROGENASE
BETA-SUBUNIT

(Aromatoleum
aromaticum) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF13247
(Fer4_11) 		3 ARG A 105
THR B  43
TRP B  42
 None
None
SF4  B1359 (-4.5A)
 1.20A 4d7hA-2ivfA:
undetectable		 4d7hA-2ivfA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lnl C-X-C CHEMOKINE
RECEPTOR TYPE 1

(Homo sapiens) 		PF00001
(7tm_1) 		3 ARG A 175
THR A 195
TRP A 198
 None
 0.91A 4d7hA-2lnlA:
undetectable		 4d7hA-2lnlA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nyh PUTATIVE DIOXYGENASE

(Paraburkholderia
xenovorans) 		PF08883
(DOPA_dioxygen) 		3 ARG A  23
THR A  28
TRP A  27
 None
 1.10A 4d7hA-2nyhA:
undetectable		 4d7hA-2nyhA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odp COMPLEMENT C2

(Homo sapiens) 		PF00089
(Trypsin)
PF00092
(VWA) 		3 ARG A 382
THR A 341
TRP A 344
 None
 1.20A 4d7hA-2odpA:
undetectable		 4d7hA-2odpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50

(Geobacillus
stearothermophilus) 		PF00135
(COesterase) 		3 ARG A 364
THR A 358
TRP A 362
 ARG  A 364 ( 0.6A)
THR  A 358 ( 0.8A)
TRP  A 362 ( 0.5A)
 1.15A 4d7hA-2ogsA:
0.4		 4d7hA-2ogsA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ola O-SUCCINYLBENZOIC
ACID SYNTHETASE

(Staphylococcus
aureus) 		PF13378
(MR_MLE_C) 		3 ARG A  29
THR A  53
TRP A  55
 None
 1.20A 4d7hA-2olaA:
1.3		 4d7hA-2olaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkx BIFUNCTIONAL PROTEIN
GLMU

(Mycobacterium
tuberculosis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		3 ARG A 253
THR A 271
TRP A 273
 None
 1.22A 4d7hA-2qkxA:
undetectable		 4d7hA-2qkxA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve3 PUTATIVE CYTOCHROME
P450 120

(Synechocystis
sp. PCC 6803) 		PF00067
(p450) 		3 ARG A 323
THR A  95
TRP A  80
 HEM  A1444 (-2.7A)
None
REA  A1445 ( 3.9A)
 1.05A 4d7hA-2ve3A:
undetectable		 4d7hA-2ve3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ARG A 620
THR A 654
TRP A 653
 None
 1.28A 4d7hA-2wanA:
0.0		 4d7hA-2wanA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp8 EXOSOME COMPLEX
EXONUCLEASE DIS3

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF13638
(PIN_4)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 ARG J 294
THR J 389
TRP J 326
 None
 1.17A 4d7hA-2wp8J:
undetectable		 4d7hA-2wp8J:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 3 ARG A 401
THR A 431
TRP A  48
 None
 1.22A 4d7hA-3a0fA:
undetectable		 4d7hA-3a0fA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bbu HEAT SHOCK PROTEIN
15

(Escherichia
coli) 		PF01479
(S4) 		3 ARG A  19
THR A  23
TRP A  16
 None
 1.17A 4d7hA-3bbuA:
undetectable		 4d7hA-3bbuA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cji POLYPROTEIN

(Senecavirus A) 		PF00073
(Rhv)
no annotation 		3 ARG A 194
THR C 169
TRP C 189
 None
 1.11A 4d7hA-3cjiA:
undetectable		 4d7hA-3cjiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dj4 BIFUNCTIONAL PROTEIN
GLMU

(Mycobacterium
tuberculosis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		3 ARG A 253
THR A 271
TRP A 273
 None
 1.26A 4d7hA-3dj4A:
undetectable		 4d7hA-3dj4A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eff VOLTAGE-GATED
POTASSIUM CHANNEL

(Streptomyces
lividans) 		PF07885
(Ion_trans_2) 		3 ARG K 117
THR K 112
TRP K 113
 None
 1.14A 4d7hA-3effK:
3.6		 4d7hA-3effK:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f08 UNCHARACTERIZED
PROTEIN Q6HG14

(Bacillus
thuringiensis) 		PF10604
(Polyketide_cyc2) 		3 ARG A  46
THR A  87
TRP A 103
 None
 1.20A 4d7hA-3f08A:
undetectable		 4d7hA-3f08A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgw PUTATIVE
PHOSPHOLIPASE B-LIKE
2

(Mus musculus) 		PF04916
(Phospholip_B) 		3 ARG A 485
THR A 101
TRP A 103
 None
 1.25A 4d7hA-3fgwA:
undetectable		 4d7hA-3fgwA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 ARG A 105
THR A  84
TRP A 102
 None
None
GOL  A 499 (-3.4A)
 1.17A 4d7hA-3g25A:
undetectable		 4d7hA-3g25A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5t TRANS-ACONITATE
3-METHYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF13847
(Methyltransf_31) 		3 ARG A 184
THR A 245
TRP A 246
 T8N  A 309 ( 2.9A)
None
EDO  A 301 ( 4.1A)
 0.99A 4d7hA-3g5tA:
undetectable		 4d7hA-3g5tA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcz POLYPROTEIN

(Yokose virus) 		PF01728
(FtsJ) 		3 ARG A 209
THR A 242
TRP A  13
 None
 1.08A 4d7hA-3gczA:
1.2		 4d7hA-3gczA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gir AMINOMETHYLTRANSFERA
SE

(Bartonella
henselae) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		3 ARG A  94
THR A 258
TRP A 259
 None
 1.22A 4d7hA-3girA:
undetectable		 4d7hA-3girA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmj FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00109
(ketoacyl-synt)
PF01648
(ACPS)
PF02801
(Ketoacyl-synt_C) 		3 ARG A1609
THR A1581
TRP A1030
 None
 0.78A 4d7hA-3hmjA:
undetectable		 4d7hA-3hmjA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbh ANGIOTENSIN-CONVERTI
NG ENZYME 2

(Homo sapiens) 		PF01401
(Peptidase_M2) 		3 ARG A 245
THR A 608
TRP A 606
 None
 1.03A 4d7hA-3kbhA:
undetectable		 4d7hA-3kbhA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ko7 D-TYROSYL-TRNA(TYR)
DEACYLASE

(Plasmodium
falciparum) 		PF02580
(Tyr_Deacylase) 		3 ARG A   7
THR A  71
TRP A  72
 None
 1.22A 4d7hA-3ko7A:
undetectable		 4d7hA-3ko7A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m49 TRANSKETOLASE

(Bacillus
anthracis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 ARG A 493
THR A 619
TRP A 622
 None
 1.21A 4d7hA-3m49A:
undetectable		 4d7hA-3m49A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mq2 16S RRNA
METHYLTRANSFERASE

(Streptoalloteichus
tenebrarius) 		PF02390
(Methyltransf_4) 		3 ARG A  60
THR A 191
TRP A 193
 SAH  A 216 (-4.5A)
SAH  A 216 (-2.7A)
SAH  A 216 (-3.7A)
 0.99A 4d7hA-3mq2A:
undetectable		 4d7hA-3mq2A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ARG A 202
THR A 197
TRP A 201
 None
 1.21A 4d7hA-3s9vA:
undetectable		 4d7hA-3s9vA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sao EXTRACELLULAR FATTY
ACID-BINDING PROTEIN

(Gallus gallus) 		PF00061
(Lipocalin) 		3 ARG A 112
THR A  63
TRP A  61
 NKN  A 161 (-3.9A)
None
None
 1.23A 4d7hA-3saoA:
undetectable		 4d7hA-3saoA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sma FRBF

(Streptomyces
rubellomurinus) 		PF02522
(Antibiotic_NAT) 		3 ARG A  92
THR A  89
TRP A  90
 None
 0.98A 4d7hA-3smaA:
undetectable		 4d7hA-3smaA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6c PUTATIVE MAND FAMILY
DEHYDRATASE

(Pantoea
ananatis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ARG A 227
THR A 403
TRP A 404
 None
 1.25A 4d7hA-3t6cA:
undetectable		 4d7hA-3t6cA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqt D-ALANINE--D-ALANINE
LIGASE

(Coxiella
burnetii) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		3 ARG A 177
THR A 160
TRP A 158
 None
 1.28A 4d7hA-3tqtA:
undetectable		 4d7hA-3tqtA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugk SACCHAROPINE
DEHYDROGENASE [NAD+,
L-LYSINE-FORMING]

(Saccharomyces
cerevisiae) 		PF05222
(AlaDh_PNT_N) 		3 ARG A 271
THR A 274
TRP A 151
 None
 1.14A 4d7hA-3ugkA:
undetectable		 4d7hA-3ugkA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vw5 CELLOBIOSE
2-EPIMERASE

(Ruminococcus
albus) 		PF07221
(GlcNAc_2-epim) 		3 ARG A 253
THR A 248
TRP A 249
 None
 1.06A 4d7hA-3vw5A:
undetectable		 4d7hA-3vw5A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ARG A 599
THR A 575
TRP A 531
 None
 0.82A 4d7hA-3wdjA:
undetectable		 4d7hA-3wdjA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7v TRANSKETOLASE

(Lactobacillus
salivarius) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 ARG A 492
THR A 617
TRP A 620
 None
 1.16A 4d7hA-4c7vA:
undetectable		 4d7hA-4c7vA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d47 LEVANSUCRASE

(Erwinia
amylovora) 		PF02435
(Glyco_hydro_68) 		3 ARG A  73
THR A  90
TRP A  93
 None
 0.68A 4d7hA-4d47A:
undetectable		 4d7hA-4d47A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4er8 TNPAREP FOR PROTEIN

(Escherichia
coli) 		no annotation 3 ARG A   6
THR A  17
TRP A  99
 None
 1.20A 4d7hA-4er8A:
undetectable		 4d7hA-4er8A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4flc ADENYLOSUCCINATE
LYASE

(Homo sapiens) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		3 ARG A 338
THR A 119
TRP A  39
 None
 1.13A 4d7hA-4flcA:
undetectable		 4d7hA-4flcA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fm9 DNA TOPOISOMERASE
2-ALPHA

(Homo sapiens) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		3 ARG A 793
THR A 934
TRP A 931
 None
 1.08A 4d7hA-4fm9A:
undetectable		 4d7hA-4fm9A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB

(Geobacillus
stearothermophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ARG A 316
THR A 310
TRP A 156
 None
 1.24A 4d7hA-4fnqA:
undetectable		 4d7hA-4fnqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjl NAPHTHALENE
1,2-DIOXYGENASE
SUBUNIT ALPHA
NAPHTHALENE
1,2-DIOXYGENASE
SUBUNIT BETA

(Pseudomonas sp.
C18) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A)
PF00866
(Ring_hydroxyl_B) 		3 ARG A 218
THR A 212
TRP B 107
 None
FE  A 502 ( 4.8A)
None
 1.16A 4d7hA-4hjlA:
undetectable		 4d7hA-4hjlA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0w PROTEASE CSPB

(Clostridium
perfringens) 		PF00082
(Peptidase_S8) 		3 ARG B 462
THR B 429
TRP B 408
 CL  B 601 (-3.9A)
None
None
 1.18A 4d7hA-4i0wB:
undetectable		 4d7hA-4i0wB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5u CHIMERIC CEL6A

(Chaetomium
thermophilum;
Humicola
insolens;
Trichoderma
reesei) 		PF01341
(Glyco_hydro_6) 		3 ARG A 105
THR A 149
TRP A  99
 None
 1.27A 4d7hA-4i5uA:
undetectable		 4d7hA-4i5uA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE

(Mammalian
rubulavirus 5) 		no annotation 3 ARG D 392
THR D 485
TRP D 467
 None
 0.82A 4d7hA-4jf7D:
undetectable		 4d7hA-4jf7D:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jo2 MONOCLONAL
ANTI-HIV-1 GP120 V3
ANTIBODY R56 HEAVY
CHAIN

(Oryctolagus
cuniculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG H  66
THR H  61
TRP H  62
 None
 1.14A 4d7hA-4jo2H:
undetectable		 4d7hA-4jo2H:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jo3 MONOCLONAL
ANTI-HIV-1 GP120 V3
ANTIBODY R20 HEAVY
CHAIN

(Oryctolagus
cuniculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG H  66
THR H  61
TRP H  62
 None
 1.04A 4d7hA-4jo3H:
undetectable		 4d7hA-4jo3H:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lp4 ADVANCED
GLYCOSYLATION END
PRODUCT-SPECIFIC
RECEPTOR

(Homo sapiens) 		PF00047
(ig)
PF08205
(C2-set_2) 		3 ARG A 228
THR A 134
TRP A 230
 None
 1.00A 4d7hA-4lp4A:
undetectable		 4d7hA-4lp4A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		3 ARG A 237
THR A  88
TRP A  89
 None
 1.16A 4d7hA-4lylA:
undetectable		 4d7hA-4lylA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0x CHLOROMUCONATE
CYCLOISOMERASE

(Rhodococcus
opacus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ARG A 118
THR A 109
TRP A 112
 None
 1.23A 4d7hA-4m0xA:
undetectable		 4d7hA-4m0xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3s EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		3 ARG A 547
THR A 456
TRP A 610
 None
 1.20A 4d7hA-4n3sA:
undetectable		 4d7hA-4n3sA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r70 BACTERIOPHYTOCHROME
(LIGHT-REGULATED
SIGNAL TRANSDUCTION
HISTIDINE KINASE),
PHYB2

(Rhodopseudomonas
palustris) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		3 ARG A 481
THR A 460
TRP A 461
 None
 1.19A 4d7hA-4r70A:
undetectable		 4d7hA-4r70A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpd CAPSID PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		3 ARG A 300
THR A 354
TRP A 355
 None
 1.26A 4d7hA-4rpdA:
undetectable		 4d7hA-4rpdA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkt AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ARG A3230
THR A3749
TRP A3747
 None
None
MES  A4004 (-3.5A)
 0.96A 4d7hA-4tktA:
undetectable		 4d7hA-4tktA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkt AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 ARG A3745
THR A3749
TRP A3747
 MES  A4004 ( 4.7A)
None
MES  A4004 (-3.5A)
 0.75A 4d7hA-4tktA:
undetectable		 4d7hA-4tktA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1c EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT C

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF05470
(eIF-3c_N) 		3 ARG C 436
THR C 453
TRP C 456
 None
 0.97A 4d7hA-4u1cC:
undetectable		 4d7hA-4u1cC:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uer EIF3C

(Lachancea
kluyveri) 		PF00189
(Ribosomal_S3_C)
PF07650
(KH_2) 		3 ARG c 436
THR c 453
TRP c 456
 None
 0.95A 4d7hA-4uerc:
2.7		 4d7hA-4uerc:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztp HEAVY CHAIN OF FAB
FRAGMENT OF RABBIT
MONOCLONAL ANTIBODY
R53

(Oryctolagus
cuniculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG H  65
THR H  60
TRP H  61
 None
 1.08A 4d7hA-4ztpH:
undetectable		 4d7hA-4ztpH:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b2d HN PROTEIN

(Mumps
rubulavirus) 		PF00423
(HN) 		3 ARG A 409
THR A 502
TRP A 484
 None
 0.87A 4d7hA-5b2dA:
undetectable		 4d7hA-5b2dA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esc HUPZ

(Streptococcus
sp. 'group A') 		PF01243
(Putative_PNPOx) 		3 ARG A  35
THR A  41
TRP A  37
 None
 0.97A 4d7hA-5escA:
undetectable		 4d7hA-5escA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h64 SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom)
PF11865
(DUF3385) 		3 ARG A2042
THR A2098
TRP A2101
 None
 1.20A 4d7hA-5h64A:
undetectable		 4d7hA-5h64A:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzr SNF2-FAMILY ATP
DEPENDENT CHROMATIN
REMODELING FACTOR
LIKE PROTEIN

(Thermothelomyces
thermophila) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		3 ARG A 475
THR A 738
TRP A 722
 SO4  A1208 (-2.8A)
None
None
 1.24A 4d7hA-5hzrA:
undetectable		 4d7hA-5hzrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i51 TRANSKETOLASE

(Scheffersomyces
stipitis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 ARG A 497
THR A 617
TRP A 620
 None
 1.22A 4d7hA-5i51A:
undetectable		 4d7hA-5i51A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE

(Porphyromonas
gingivalis) 		PF10459
(Peptidase_S46) 		3 ARG A 281
THR A 580
TRP A  26
 None
 1.17A 4d7hA-5jwfA:
undetectable		 4d7hA-5jwfA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k50 L-THREONINE
3-DEHYDROGENASE

(Trypanosoma
brucei) 		no annotation 3 ARG A1167
THR A1072
TRP A1073
 None
 0.93A 4d7hA-5k50A:
undetectable		 4d7hA-5k50A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lf8 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 17

(Homo sapiens) 		PF00293
(NUDIX) 		3 ARG A 277
THR A 270
TRP A 174
 PO4  A 401 (-2.7A)
None
None
 1.20A 4d7hA-5lf8A:
undetectable		 4d7hA-5lf8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lly DIGUANYLATE CYCLASE
(GGDEF)
DOMAIN-CONTAINING
PROTEIN

(Idiomarina sp.
A28L) 		no annotation 3 ARG D 467
THR D 446
TRP D 447
 None
 1.27A 4d7hA-5llyD:
undetectable		 4d7hA-5llyD:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lv9 THERMOPHILIC
TRYPTOPHAN
HALOGENASE

(Streptomyces
violaceusniger) 		PF04820
(Trp_halogenase) 		3 ARG A 426
THR A 417
TRP A 420
 None
 0.98A 4d7hA-5lv9A:
undetectable		 4d7hA-5lv9A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0c TETANUS TOXIN

(Clostridium
tetani) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		3 ARG A 528
THR A 155
TRP A  44
 None
 0.95A 4d7hA-5n0cA:
undetectable		 4d7hA-5n0cA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN

(Bacillus
coagulans) 		no annotation 3 ARG A 121
THR A 231
TRP A 266
 None
 1.28A 4d7hA-5o7gA:
undetectable		 4d7hA-5o7gA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 3 ARG A 461
THR A 390
TRP A 388
 None
 1.21A 4d7hA-5oc1A:
undetectable		 4d7hA-5oc1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olc GALACTONATE
DEHYDRATASE

(Zobellia
galactanivorans) 		no annotation 3 ARG A 332
THR A 300
TRP A 301
 None
 1.19A 4d7hA-5olcA:
undetectable		 4d7hA-5olcA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oms CYTOCHROME P450

(Amycolatopsis
sp. ATCC 39116) 		no annotation 3 ARG A  32
THR A 289
TRP A 293
 None
 1.09A 4d7hA-5omsA:
undetectable		 4d7hA-5omsA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uak CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Homo sapiens) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		3 ARG A1048
THR A1086
TRP A1089
 None
 1.10A 4d7hA-5uakA:
undetectable		 4d7hA-5uakA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrb TRANSKETOLASE

(Neisseria
gonorrhoeae) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 ARG A 489
THR A 612
TRP A 615
 None
 1.28A 4d7hA-5vrbA:
undetectable		 4d7hA-5vrbA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w81 CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Danio rerio) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		3 ARG A1056
THR A1094
TRP A1097
 None
 1.15A 4d7hA-5w81A:
1.8		 4d7hA-5w81A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnm PHOTOSYSTEM II CP47
REACTION CENTER
PROTEIN

(Pisum sativum) 		no annotation 3 ARG B 357
THR B 361
TRP B 275
 None
 1.23A 4d7hA-5xnmB:
undetectable		 4d7hA-5xnmB:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog RNA POLYMERASE II
THIRD LARGEST
SUBUNIT B44, PART OF
CENTRAL CORE

(Komagataella
phaffii) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L) 		3 ARG C 227
THR C 208
TRP C 209
 None
 0.91A 4d7hA-5xogC:
undetectable		 4d7hA-5xogC:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z4i UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 20

(Homo sapiens) 		no annotation 3 ARG A  80
THR A  73
TRP A  82
 None
 1.13A 4d7hA-5z4iA:
undetectable		 4d7hA-5z4iA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6y APRA
METHYLTRANSFERASE 2

(Moorea
bouillonii) 		no annotation 3 ARG A 967
THR A 942
TRP A 979
 None
 1.22A 4d7hA-6d6yA:
undetectable		 4d7hA-6d6yA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dcq ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 3 ARG A 350
THR A 394
TRP A 395
 None
 1.28A 4d7hA-6dcqA:
undetectable		 4d7hA-6dcqA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 3 ARG A  25
THR A 495
TRP A 492
 None
 1.19A 4d7hA-6ercA:
undetectable		 4d7hA-6ercA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fbt LYTIC MUREIN
TRANSGLYCOSYLASE

(Pseudomonas
aeruginosa) 		no annotation 3 ARG A 608
THR A 340
TRP A 343
 None
 1.07A 4d7hA-6fbtA:
undetectable		 4d7hA-6fbtA:
17.05