SIMILAR PATTERNS OF AMINO ACIDS FOR 4D39_A_MTLA870_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0c XYLOSE ISOMERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF01261
(AP_endonuc_2) 		4 GLU A 178
ILE A 175
ASN A 115
ASP A 119
 None
 1.09A 4d39A-1a0cA:
0.0		 4d39A-1a0cA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hle HORSE LEUKOCYTE
ELASTASE INHIBITOR

(Equus caballus) 		PF00079
(Serpin) 		4 ARG A 154
ASN A 158
GLU A 156
ILE A 157
 None
 1.11A 4d39A-1hleA:
0.0		 4d39A-1hleA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jov HI1317

(Haemophilus
influenzae) 		PF01263
(Aldose_epim) 		4 ASN A 227
GLU A 189
ILE A 187
ASN A 159
 None
 1.07A 4d39A-1jovA:
undetectable		 4d39A-1jovA:
21.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lzx NITRIC-OXIDE
SYNTHASE

(Rattus
norvegicus) 		PF02898
(NO_synthase) 		6 SER A 477
ARG A 481
ASN A 498
ASN A 569
ASP A 709
TRP A 711
 None
 0.46A 4d39A-1lzxA:
59.5		 4d39A-1lzxA:
62.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		8 SER A 246
ARG A 250
ASN A 267
GLU A 269
ILE A 270
ASN A 338
ASP A 478
TRP A 480
 None
 0.48A 4d39A-1m9qA:
62.4		 4d39A-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfa HUMAN TRANSCRIPTION
FACTOR NFATC1

(Homo sapiens) 		PF00554
(RHD_DNA_bind) 		4 SER A  23
ASN A 170
GLU A 173
ILE A 172
 None
 1.09A 4d39A-1nfaA:
0.0		 4d39A-1nfaA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh1 STAPHOSTATIN A

(Staphylococcus
aureus) 		PF09022
(Staphostatin_A) 		4 ASN A  25
ILE A  26
ASN A  85
TRP A  31
 None
 0.92A 4d39A-1oh1A:
0.0		 4d39A-1oh1A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd2 HEMATOPOIETIC
PROSTAGLANDIN D
SYNTHASE

(Rattus
norvegicus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 SER 1  64
ARG 1  14
ILE 1  17
TRP 1 148
 GSH  1 301 (-2.6A)
GSH  1 301 (-3.4A)
None
None
 0.92A 4d39A-1pd21:
0.0		 4d39A-1pd21:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		5 SER A 256
ARG A 260
GLU A 279
ASN A 348
TRP A 490
 None
 0.51A 4d39A-1qw5A:
56.9		 4d39A-1qw5A:
57.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqj OLIGOXYLOGLUCAN
REDUCING-END-SPECIFI
C CELLOBIOHYDROLASE

(Geotrichum sp.
M128) 		PF15899
(BNR_6) 		4 SER A 133
ASN A  75
GLU A  98
ASN A 134
 None
 0.95A 4d39A-1sqjA:
undetectable		 4d39A-1sqjA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t2s ARGONAUTE 2

(Drosophila
melanogaster) 		PF02170
(PAZ) 		4 ASN A  21
ILE A  20
ASN A  25
ASP A  27
 None
 0.93A 4d39A-1t2sA:
undetectable		 4d39A-1t2sA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v40 GLUTATHIONE-REQUIRIN
G PROSTAGLANDIN D
SYNTHASE

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 SER A  64
ARG A  14
ILE A  17
TRP A 148
 GSH  A3200 (-2.5A)
O16  A3201 ( 3.8A)
None
None
 1.06A 4d39A-1v40A:
undetectable		 4d39A-1v40A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w18 LEVANSUCRASE

(Gluconacetobacter
diazotrophicus) 		PF02435
(Glyco_hydro_68) 		4 ARG A 269
ILE A 270
ASN A 547
ASP A 545
 None
 1.02A 4d39A-1w18A:
undetectable		 4d39A-1w18A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1za4 THROMBOSPONDIN 1

(Homo sapiens) 		PF02210
(Laminin_G_2) 		4 ARG A 180
ILE A  49
ASN A 189
ASP A  45
 None
 0.97A 4d39A-1za4A:
undetectable		 4d39A-1za4A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bii NITRATE REDUCTASE
[NADPH]

(Ogataea angusta) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 SER A 426
ARG A 144
GLU A 146
ASN A 423
 None
SO4  A 602 (-4.3A)
None
None
 1.05A 4d39A-2biiA:
undetectable		 4d39A-2biiA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c7l PHYCOERYTHROCYANIN
ALPHA CHAIN
PHYCOERYTHROCYANIN
BETA CHAIN

(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		PF00502
(Phycobilisome)
PF00502
(Phycobilisome) 		4 ASN B  25
GLU B  23
ILE B  24
ASN A  46
 None
 0.93A 4d39A-2c7lB:
undetectable		 4d39A-2c7lB:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cit ENDOGLUCANASE H

(Ruminiclostridium
thermocellum) 		PF02156
(Glyco_hydro_26) 		4 SER A 166
ASN A 128
ILE A 119
ASN A 160
 None
 1.09A 4d39A-2citA:
undetectable		 4d39A-2citA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2crw ADP-RIBOSYLATION
FACTOR
GTPASE-ACTIVATING
PROTEIN 3

(Homo sapiens) 		PF01412
(ArfGap) 		4 SER A  76
ILE A  16
ASN A  77
ASP A  10
 None
 1.11A 4d39A-2crwA:
undetectable		 4d39A-2crwA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6d GLUCOAMYLASE GLU1

(Saccharomycopsis
fibuligera) 		PF00723
(Glyco_hydro_15) 		4 ASN A 408
ILE A 407
ASN A 398
ASP A 403
 None
 1.10A 4d39A-2f6dA:
undetectable		 4d39A-2f6dA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		4 ASN A 440
GLU A 385
ASN A 376
ASP A 339
 None
 1.04A 4d39A-2gj4A:
undetectable		 4d39A-2gj4A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ije GUANINE
NUCLEOTIDE-RELEASING
PROTEIN

(Mus musculus) 		PF00617
(RasGEF) 		4 SER S1124
ARG S1127
GLU S1085
ILE S1086
 None
 0.95A 4d39A-2ijeS:
undetectable		 4d39A-2ijeS:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iop CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 ARG A  33
ILE A 204
ASN A  38
ASP A  41
 None
None
ADP  A1001 (-3.9A)
None
 1.06A 4d39A-2iopA:
undetectable		 4d39A-2iopA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nd4 AMYLASE-BINDING
PROTEIN ABPA

(Streptococcus
parasanguinis) 		no annotation 4 ARG A 100
ASN A  39
ILE A 104
TRP A  31
 None
 1.00A 4d39A-2nd4A:
undetectable		 4d39A-2nd4A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA

(Homo sapiens) 		PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8) 		4 SER B1353
ARG B1355
ILE B1349
ASP B1208
 None
 1.11A 4d39A-2nvuB:
undetectable		 4d39A-2nvuB:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7p RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Escherichia
coli) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 ARG A 141
ASN A 294
ILE A 293
TRP A 252
 None
 1.09A 4d39A-2o7pA:
undetectable		 4d39A-2o7pA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obi PHOSPHOLIPID
HYDROPEROXIDE
GLUTATHIONE
PEROXIDASE (GPX4)

(Homo sapiens) 		PF00255
(GSHPx) 		4 ASN A  86
GLU A  88
ILE A  89
ASN A  76
 None
 1.03A 4d39A-2obiA:
undetectable		 4d39A-2obiA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p31 GLUTATHIONE
PEROXIDASE 7

(Homo sapiens) 		PF00255
(GSHPx) 		4 ASN A  97
GLU A  99
ILE A 100
ASN A  87
 None
 1.10A 4d39A-2p31A:
undetectable		 4d39A-2p31A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p6w PUTATIVE
GLYCOSYLTRANSFERASE
(MANNOSYLTRANSFERASE
) INVOLVED IN
GLYCOSYLATING THE
PBCV-1 MAJOR CAPSID
PROTEIN

(Paramecium
bursaria
Chlorella virus
1) 		PF05637
(Glyco_transf_34) 		4 ARG A 166
ASN A 102
ILE A 103
TRP A  73
 None
 0.94A 4d39A-2p6wA:
undetectable		 4d39A-2p6wA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pop MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE
7-INTERACTING
PROTEIN 1

(Homo sapiens) 		PF00481
(PP2C) 		4 ARG A 187
ASN A 306
GLU A 308
ILE A 309
 None
 0.77A 4d39A-2popA:
undetectable		 4d39A-2popA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3z TRANSGLUTAMINASE 2

(Homo sapiens) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		4 SER A 419
GLU A 314
ILE A 313
ASN A 417
 None
 1.01A 4d39A-2q3zA:
undetectable		 4d39A-2q3zA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		4 ARG A 296
ASN A 351
GLU A 349
ILE A 353
 None
 1.09A 4d39A-2vmfA:
undetectable		 4d39A-2vmfA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		4 ASN A 440
GLU A 385
ASN A 376
ASP A 339
 None
 1.02A 4d39A-3cemA:
undetectable		 4d39A-3cemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d9i RNA-BINDING PROTEIN
16

(Homo sapiens) 		PF04818
(CTD_bind) 		4 SER A  89
GLU A 126
ILE A 127
ASN A  90
 GOL  A1002 (-3.1A)
None
GOL  A1002 (-4.8A)
SO4  A 147 ( 3.4A)
 1.12A 4d39A-3d9iA:
undetectable		 4d39A-3d9iA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dc7 PUTATIVE
UNCHARACTERIZED
PROTEIN LP_3323

(Lactobacillus
plantarum) 		PF13472
(Lipase_GDSL_2) 		4 SER A  63
ARG A  75
ASN A  93
ASP A  94
 None
 1.12A 4d39A-3dc7A:
undetectable		 4d39A-3dc7A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e13 PUTATIVE IRON-UPTAKE
ABC TRANSPORT
SYSTEM,PERIPLASMIC
IRON-BINDING PROTEIN

(Campylobacter
jejuni) 		PF13343
(SBP_bac_6) 		4 ARG X 105
ILE X 102
ASN X 273
ASP X  18
 FE  X 326 ( 3.9A)
None
None
None
 1.07A 4d39A-3e13X:
undetectable		 4d39A-3e13X:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 266
ASN A 283
GLU A 285
ASN A 354
 AT2  A 906 (-3.6A)
None
None
None
 1.06A 4d39A-3e7gA:
55.5		 4d39A-3e7gA:
58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 266
GLU A 285
ASN A 354
TRP A 496
 AT2  A 906 (-3.6A)
None
None
None
 0.85A 4d39A-3e7gA:
55.5		 4d39A-3e7gA:
58.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqq BENZENE
1,2-DIOXYGENASE
SUBUNIT ALPHA

(Pseudomonas
putida) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 ASN A 419
ILE A 417
ASN A 409
ASP A 408
 None
 1.10A 4d39A-3eqqA:
undetectable		 4d39A-3eqqA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgv UNCHARACTERIZED
PROTEIN WITH
FERREDOXIN-LIKE FOLD

(Ruegeria
pomeroyi) 		PF03992
(ABM) 		4 ASN A  90
GLU A  88
ILE A  89
ASP A  85
 None
None
UNL  A 205 ( 4.1A)
None
 1.05A 4d39A-3fgvA:
undetectable		 4d39A-3fgvA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk2 GLUCOCORTICOID
RECEPTOR DNA-BINDING
FACTOR 1

(Homo sapiens) 		PF00620
(RhoGAP) 		4 SER A1383
GLU A1426
ILE A1429
ASN A1386
 None
 1.07A 4d39A-3fk2A:
undetectable		 4d39A-3fk2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 SER A 204
ARG A 175
ASN A 235
ASP A 261
 None
 1.12A 4d39A-3gozA:
undetectable		 4d39A-3gozA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grf ORNITHINE
CARBAMOYLTRANSFERASE

(Giardia
intestinalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 SER A  13
ARG A 179
GLU A 210
ILE A 211
 None
 1.01A 4d39A-3grfA:
undetectable		 4d39A-3grfA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		4 SER A   8
ARG A  10
ILE A   4
ASP A-137
 None
 1.02A 4d39A-3l2jA:
undetectable		 4d39A-3l2jA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1

(Bacillus
anthracis) 		PF00202
(Aminotran_3) 		4 ASN A 367
GLU A 370
ILE A 369
ASP A 371
 None
 1.11A 4d39A-3l44A:
undetectable		 4d39A-3l44A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3max HISTONE DEACETYLASE
2

(Homo sapiens) 		PF00850
(Hist_deacetyl) 		4 SER A 272
ASN A 312
ASN A 280
ASP A 239
 None
 1.08A 4d39A-3maxA:
undetectable		 4d39A-3maxA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF01547
(SBP_bac_1) 		4 SER A 521
ASN A 482
GLU A 484
ILE A 485
 None
 0.97A 4d39A-3ombA:
undetectable		 4d39A-3ombA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p09 BETA-LACTAMASE

(Francisella
tularensis) 		PF13354
(Beta-lactamase2) 		4 ASN A 162
GLU A 160
ILE A 161
ASN A 128
 None
 1.03A 4d39A-3p09A:
undetectable		 4d39A-3p09A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p14 L-RHAMNOSE ISOMERASE

(Bacillus
halodurans) 		PF06134
(RhaA) 		4 SER A 273
ASN A 270
GLU A 306
ASN A 314
 None
 1.08A 4d39A-3p14A:
undetectable		 4d39A-3p14A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgl CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1

(Homo sapiens) 		PF03031
(NIF) 		4 SER A 208
ASN A 187
ASN A 207
ASP A  96
 None
None
MG  A   1 (-2.7A)
MG  A   1 (-2.5A)
 1.00A 4d39A-3pglA:
undetectable		 4d39A-3pglA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps0 CRISPR-ASSOCIATED
PROTEIN, CSA2

(Sulfolobus
solfataricus) 		PF01905
(DevR) 		4 ARG A 147
GLU A 300
ILE A 299
ASP A 268
 None
 1.02A 4d39A-3ps0A:
undetectable		 4d39A-3ps0A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 SER A 543
ARG A 570
GLU A 546
ILE A 571
 None
 1.06A 4d39A-3qr1A:
undetectable		 4d39A-3qr1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tql ARGININE-BINDING
PROTEIN

(Coxiella
burnetii) 		PF00497
(SBP_bac_3) 		4 SER A 188
ARG A 190
GLU A 180
TRP A 204
 None
 0.86A 4d39A-3tqlA:
undetectable		 4d39A-3tqlA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttg PUTATIVE
AMINOMETHYLTRANSFERA
SE

(Leptospirillum
rubarum) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 SER A 300
ARG A 262
GLU A 206
ILE A 302
 None
 0.91A 4d39A-3ttgA:
undetectable		 4d39A-3ttgA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tts BETA-GALACTOSIDASE

(Bacillus
circulans) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		4 ARG A 135
GLU A  67
ILE A  66
ASP A  64
 None
 1.06A 4d39A-3ttsA:
undetectable		 4d39A-3ttsA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw5 TRANSGLUTAMINASE
ELICITOR

(Phytophthora
sojae) 		PF16683
(TGase_elicitor) 		4 ASN A 165
GLU A 477
ILE A 478
ASN A 373
 None
 1.09A 4d39A-3tw5A:
undetectable		 4d39A-3tw5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wz1 AGARASE

(Microbulbifer
thermotolerans) 		PF00722
(Glyco_hydro_16) 		4 SER A 144
ASN A  70
ILE A  69
TRP A 138
 None
 1.03A 4d39A-3wz1A:
undetectable		 4d39A-3wz1A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 SER B2326
ASN B2318
ILE B2321
ASN B1472
 None
 0.78A 4d39A-3zefB:
undetectable		 4d39A-3zefB:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zy3 PUTATIVE GDP-FUCOSE
PROTEIN
O-FUCOSYLTRANSFERASE
1

(Caenorhabditis
elegans) 		PF10250
(O-FucT) 		4 ASN A 318
GLU A 316
ILE A 317
ASP A 311
 None
 1.10A 4d39A-3zy3A:
undetectable		 4d39A-3zy3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dy0 GLIA-DERIVED NEXIN

(Homo sapiens) 		PF00079
(Serpin) 		4 ASN A 111
GLU A 118
ASN A 166
TRP A 137
 None
 1.10A 4d39A-4dy0A:
undetectable		 4d39A-4dy0A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX

(Bacillus cereus) 		PF00091
(Tubulin) 		4 SER A 165
GLU A 372
ILE A 373
ASN A 162
 None
 0.98A 4d39A-4ei8A:
undetectable		 4d39A-4ei8A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhq SERUM PARAOXONASE BY
DIRECTED EVOLUTION

(synthetic
construct) 		PF01731
(Arylesterase) 		4 SER A 272
GLU A  53
ASN A 227
ASP A 169
 None
CA  A 402 (-3.4A)
None
CA  A 401 (-2.1A)
 0.87A 4d39A-4hhqA:
undetectable		 4d39A-4hhqA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i05 CATHEPSIN B-LIKE
PEPTIDASE (C01
FAMILY)

(Schistosoma
mansoni) 		PF00112
(Peptidase_C1) 		4 SER A 315
GLU A 310
ILE A 313
ASN A 226
 None
 1.10A 4d39A-4i05A:
undetectable		 4d39A-4i05A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idi ORYZA SATIVA
RURM1-RELATED

(Plasmodium
yoelii) 		PF09138
(Urm1) 		4 SER A  55
ARG A  44
GLU A  37
ILE A  40
 None
 1.12A 4d39A-4idiA:
undetectable		 4d39A-4idiA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j4x NP PROTEIN

(Sandfly fever
Naples
phlebovirus) 		PF05733
(Tenui_N) 		4 SER A 110
ASN A 101
GLU A  99
ASN A  66
 None
 0.84A 4d39A-4j4xA:
undetectable		 4d39A-4j4xA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jx0 HYPOTHETICAL PROTEIN

(Bacteroides
fragilis) 		PF08522
(DUF1735) 		4 ARG A 265
GLU A 210
ILE A 209
ASN A 206
 None
 1.09A 4d39A-4jx0A:
undetectable		 4d39A-4jx0A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9m RAS GUANYL-RELEASING
PROTEIN 1

(Homo sapiens) 		PF00130
(C1_1)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF13405
(EF-hand_6) 		4 SER A 456
ASN A 252
GLU A 245
ILE A 248
 None
 0.89A 4d39A-4l9mA:
undetectable		 4d39A-4l9mA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASN A 867
ILE A 868
ASN A 933
ASP A 937
 None
 0.98A 4d39A-4ldeA:
2.1		 4d39A-4ldeA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4na3 POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 ASN A 324
GLU A 322
ILE A 323
ASN A 392
 None
 0.64A 4d39A-4na3A:
undetectable		 4d39A-4na3A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o87 N-TAGGED NUCLEASE

(Millerozyma
acaciae) 		no annotation 4 ASN A 277
ILE A 186
ASN A 192
TRP A 182
 None
 0.94A 4d39A-4o87A:
undetectable		 4d39A-4o87A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oet PUTATIVE PEPTIDE
ABC-TRANSPORT SYSTEM
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Campylobacter
jejuni) 		PF00496
(SBP_bac_5) 		4 GLU A  14
ILE A  15
ASN A 154
TRP A 168
 None
 0.96A 4d39A-4oetA:
undetectable		 4d39A-4oetA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5t LIPOPROTEIN

(Streptococcus
mutans) 		PF03180
(Lipoprotein_9) 		4 ASN A 235
GLU A 108
ILE A 236
ASN A  90
 None
 1.02A 4d39A-4q5tA:
undetectable		 4d39A-4q5tA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlz SJCHGC07024 PROTEIN

(Schistosoma
japonicum) 		PF00719
(Pyrophosphatase) 		4 ASN A  64
GLU A  56
ILE A  57
ASP A 115
 None
CO  A 403 (-3.4A)
None
CO  A 403 ( 3.5A)
 0.99A 4d39A-4qlzA:
undetectable		 4d39A-4qlzA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru3 PUNCTURING PROTEIN
GP41

(Pseudomonas
virus SN) 		no annotation 4 SER A 160
ARG A 162
ASN A 165
ILE A 166
 None
 0.86A 4d39A-4ru3A:
undetectable		 4d39A-4ru3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvi AMINOTRANSFERASE,
CLASS IV

(Brucella
abortus) 		PF01063
(Aminotran_4) 		4 ARG A  36
ILE A  42
ASP A 136
TRP A 119
 None
 0.75A 4d39A-4tviA:
undetectable		 4d39A-4tviA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u5a SPOROZOITE MICRONEME
PROTEIN ESSENTIAL
FOR CELL TRAVERSAL

(Plasmodium
berghei) 		no annotation 4 ASN A 119
GLU A 117
ILE A 116
ASP A  55
 None
 0.90A 4d39A-4u5aA:
2.5		 4d39A-4u5aA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uei STEROL CARRIER
PROTEIN
2/3-OXOACYL-COA
THIOLASE

(Helicoverpa
armigera) 		PF02036
(SCP2) 		4 ARG A  48
GLU A  37
ILE A  44
ASN A  69
 None
 0.99A 4d39A-4ueiA:
undetectable		 4d39A-4ueiA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wtv PHOSPHATIDYLINOSITOL
4-KINASE TYPE
2-BETA,ENDOLYSIN,PHO
SPHATIDYLINOSITOL
4-KINASE TYPE 2-BETA

(Homo sapiens;
Escherichia
virus T4) 		PF00454
(PI3_PI4_kinase)
PF00959
(Phage_lysozyme) 		4 ASN A1001
ILE A1002
ASN A1067
ASP A1071
 None
 1.04A 4d39A-4wtvA:
1.0		 4d39A-4wtvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8q UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF08713
(DNA_alkylation) 		4 SER A 163
ARG A 123
GLU A 158
ASN A 166
 None
 1.05A 4d39A-4x8qA:
undetectable		 4d39A-4x8qA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a53 REGULATOR OF
RIBOSOME
BIOSYNTHESIS
RIBOSOME BIOGENESIS
PROTEIN RPF2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04939
(RRS1)
PF04427
(Brix) 		4 SER C 169
ARG C 166
ASN A  25
ASP C 171
 SO4  C1254 (-3.2A)
SO4  C1254 (-3.1A)
None
None
 0.91A 4d39A-5a53C:
undetectable		 4d39A-5a53C:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 SER A  98
ASN A 237
GLU A 245
ASN A  99
 None
 1.05A 4d39A-5amqA:
2.4		 4d39A-5amqA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwa ORNITHINE
DECARBOXYLASE
ANTIZYME 1

(Homo sapiens) 		PF02100
(ODC_AZ) 		4 ARG B 131
ASN B 117
GLU B 105
ASP B 111
 None
 1.11A 4d39A-5bwaB:
undetectable		 4d39A-5bwaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cuv ACIDOCALCISOMAL
PYROPHOSPHATASE

(Trypanosoma
cruzi) 		PF00719
(Pyrophosphatase) 		4 ASN A 247
GLU A 239
ILE A 240
ASP A 293
 None
 0.96A 4d39A-5cuvA:
undetectable		 4d39A-5cuvA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f2v GTP
PYROPHOSPHOKINASE
YJBM

(Bacillus
subtilis) 		no annotation 4 SER V  38
ARG V  28
ILE V  40
ASP V  85
 None
 1.09A 4d39A-5f2vV:
undetectable		 4d39A-5f2vV:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD

(Escherichia
coli;
Danio rerio) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		4 SER A 353
ARG A 355
ILE A 349
ASP A 208
 None
 0.98A 4d39A-5gpqA:
undetectable		 4d39A-5gpqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 ASN A 379
GLU A 308
ILE A 348
ASP A 180
 None
PO4  A 802 ( 4.4A)
None
None
 0.88A 4d39A-5gslA:
undetectable		 4d39A-5gslA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8) 		4 SER A 407
ARG A 409
ILE A 403
ASP A 262
 None
 1.04A 4d39A-5hzwA:
undetectable		 4d39A-5hzwA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihe DNA POLYMERASE II
SMALL SUBUNIT

(Pyrococcus
abyssi) 		PF00149
(Metallophos) 		4 SER A 394
GLU A 389
ILE A 392
TRP A 379
 None
 1.03A 4d39A-5iheA:
undetectable		 4d39A-5iheA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikp GLYCOGEN
PHOSPHORYLASE, BRAIN
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		4 ASN A 440
GLU A 385
ASN A 376
ASP A 339
 None
 1.11A 4d39A-5ikpA:
undetectable		 4d39A-5ikpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irc RHO
GTPASE-ACTIVATING
PROTEIN 35

(Rattus
norvegicus) 		PF00620
(RhoGAP) 		4 SER A1383
GLU A1426
ILE A1429
ASN A1386
 None
 1.01A 4d39A-5ircA:
undetectable		 4d39A-5ircA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iw9 BASEPLATE WEDGE
PROTEIN GP25

(Escherichia
virus T4) 		PF04965
(GPW_gp25) 		4 SER A  79
ASN A  76
GLU A  74
ILE A  77
 None
 1.05A 4d39A-5iw9A:
undetectable		 4d39A-5iw9A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyg ACTIN-LIKE ATPASE

(Magnetospirillum
magneticum) 		PF06723
(MreB_Mbl) 		4 ARG A 305
GLU A 263
ILE A 262
ASP A 260
 None
 1.07A 4d39A-5jygA:
undetectable		 4d39A-5jygA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbf CAMP-DEPENDENT
PROTEIN KINASE
REGULATORY SUBUNIT,
PUTATIVE

(Plasmodium
falciparum) 		PF00027
(cNMP_binding) 		4 ARG A 181
GLU A 176
ILE A 180
ASN A 203
 None
 1.04A 4d39A-5kbfA:
undetectable		 4d39A-5kbfA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3

(Porphyromonas
gingivalis) 		no annotation 4 ASN A 222
GLU A 225
ILE A 252
ASN A 271
 None
 1.00A 4d39A-5nf4A:
undetectable		 4d39A-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nzz TGF-BETA-ACTIVATED
KINASE 1 AND
MAP3K7-BINDING
PROTEIN 1

(Homo sapiens) 		no annotation 4 ARG A 187
ASN A 306
GLU A 308
ILE A 309
 None
 0.79A 4d39A-5nzzA:
undetectable		 4d39A-5nzzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3u PTS SYSTEM, IIA
COMPONENT

(Streptococcus
pneumoniae) 		PF03610
(EIIA-man) 		4 SER A 111
ARG A   7
GLU A 120
ILE A 121
 None
 0.94A 4d39A-5t3uA:
undetectable		 4d39A-5t3uA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 ASN A 125
ILE A 223
ASN A 185
ASP A 188
 None
 1.08A 4d39A-5xsyA:
0.7		 4d39A-5xsyA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cl6 TAIL FIBER PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 SER A 511
ARG A 527
ILE A 484
ASP A 508
 None
 1.11A 4d39A-6cl6A:
undetectable		 4d39A-6cl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6elw PHOSPHOLIPID
HYDROPEROXIDE
GLUTATHIONE
PEROXIDASE,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 ASN A  86
GLU A  88
ILE A  89
ASN A  76
 None
 1.03A 4d39A-6elwA:
undetectable		 4d39A-6elwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6epd 26S PROTEASOME
SUBUNIT S5A

(Rattus
norvegicus) 		no annotation 4 ASN W  12
GLU W 118
ILE W  84
ASP W 119
 None
 0.92A 4d39A-6epdW:
undetectable		 4d39A-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fml RUVB-LIKE HELICASE

(Chaetomium
thermophilum) 		no annotation 4 SER D 309
ILE D 305
ASN D 312
ASP D 348
 None
 1.01A 4d39A-6fmlD:
undetectable		 4d39A-6fmlD:
undetectable