SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9W_A_VGHA1158_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea9 CYCLOMALTODEXTRINASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		5 LEU C 541
PHE C 384
VAL C 531
PHE C 383
GLN C 387
 None
 1.32A 4c9wA-1ea9C:
0.0		 4c9wA-1ea9C:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6u TRYPTOPHANYL-TRNA
SYNTHETASE

(Homo sapiens) 		PF00579
(tRNA-synt_1b) 		5 PHE A 247
PHE A 293
VAL A 251
ASP A 237
ASP A 198
 None
 1.45A 4c9wA-1r6uA:
0.0		 4c9wA-1r6uA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6o FERRITIN HEAVY CHAIN

(Trichoplusia ni) 		PF00210
(Ferritin) 		5 PHE M  46
VAL M  51
TRP M 102
PHE M  60
GLN M  38
 None
 1.03A 4c9wA-1z6oM:
undetectable		 4c9wA-1z6oM:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqx MEMBRANE LIPOPROTEIN
TMPC

(Treponema
pallidum) 		PF02608
(Bmp) 		5 LEU A 105
MET A  24
VAL A  82
PHE A  36
GLN A  39
 None
None
None
GMP  A 400 (-3.8A)
None
 1.26A 4c9wA-2fqxA:
0.2		 4c9wA-2fqxA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2izv SUPPRESSOR OF
CYTOKINE SIGNALING 4

(Homo sapiens) 		PF00017
(SH2)
PF07525
(SOCS_box) 		5 LEU A 278
ASN A 282
PHE A 320
VAL A 275
ASP A 312
 None
None
None
None
EDO  A1431 (-3.7A)
 1.14A 4c9wA-2izvA:
0.0		 4c9wA-2izvA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mph PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3

(Homo sapiens) 		PF00254
(FKBP_C) 		5 TYR A 135
LEU A 179
PHE A 216
PHE A 145
VAL A 218
 None
 1.32A 4c9wA-2mphA:
0.0		 4c9wA-2mphA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		5 LEU A1261
PHE A1160
PHE A1284
MET A1113
VAL A1123
 None
 1.49A 4c9wA-2nz9A:
0.0		 4c9wA-2nz9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q30 UNCHARACTERIZED
PROTEIN

(Desulfovibrio
alaskensis) 		PF07883
(Cupin_2) 		5 LEU A  56
PHE A  37
PHE A  39
VAL A 103
PHE A  21
 None
 0.80A 4c9wA-2q30A:
0.0		 4c9wA-2q30A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qry THIAMINE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF13343
(SBP_bac_6) 		5 LEU A  54
PHE A 262
VAL A  24
PHE A 265
GLN A 272
 None
 1.38A 4c9wA-2qryA:
0.0		 4c9wA-2qryA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		5 PHE A2036
PHE A1988
MET A1456
VAL A1453
PHE A1423
 None
 1.48A 4c9wA-2vz9A:
undetectable		 4c9wA-2vz9A:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzs PUTATIVE
UNCHARACTERIZED
PROTEIN

(Aquifex
aeolicus) 		PF01867
(Cas_Cas1) 		5 LEU A 271
PHE A  40
PHE A  42
VAL A   4
PHE A  65
 None
 0.86A 4c9wA-2yzsA:
undetectable		 4c9wA-2yzsA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zfu CEREBRAL PROTEIN 1

(Homo sapiens) 		PF05148
(Methyltransf_8) 		5 LEU A 375
PHE A 403
VAL A 407
PHE A 397
GLN A 449
 None
 1.32A 4c9wA-2zfuA:
undetectable		 4c9wA-2zfuA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cny INOSITOL CATABOLISM
PROTEIN IOLE

(Lactobacillus
plantarum) 		PF01261
(AP_endonuc_2) 		5 PHE A 243
MET A 242
VAL A 219
ASP A 189
PHE A 234
 None
 1.44A 4c9wA-3cnyA:
undetectable		 4c9wA-3cnyA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e38 TWO-DOMAIN PROTEIN
CONTAINING PREDICTED
PHP-LIKE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bacteroides
vulgatus) 		PF16392
(DUF5001) 		5 TYR A 359
ASN A 296
PHE A 349
VAL A 346
PHE A 273
 None
 1.45A 4c9wA-3e38A:
undetectable		 4c9wA-3e38A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kar KINESIN-LIKE PROTEIN
KAR3

(Saccharomyces
cerevisiae) 		PF00225
(Kinesin) 		5 LEU A 711
PHE A 436
PHE A 438
MET A 422
VAL A 424
 None
 1.44A 4c9wA-3karA:
undetectable		 4c9wA-3karA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no4 CREATININE
AMIDOHYDROLASE

(Nostoc
punctiforme) 		PF02633
(Creatininase) 		5 LEU A 128
PHE A 104
PHE A 106
VAL A 139
PHE A  23
 None
 0.98A 4c9wA-3no4A:
undetectable		 4c9wA-3no4A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no4 CREATININE
AMIDOHYDROLASE

(Nostoc
punctiforme) 		PF02633
(Creatininase) 		5 TYR A 125
PHE A 104
PHE A 106
VAL A 139
PHE A  23
 None
 0.87A 4c9wA-3no4A:
undetectable		 4c9wA-3no4A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqm RIBOSOME-ASSOCIATED
FACTOR Y

(Coxiella
burnetii) 		PF02482
(Ribosomal_S30AE) 		5 LEU A  77
PHE A  41
MET A  70
VAL A  74
GLN A   8
 None
 1.29A 4c9wA-3tqmA:
undetectable		 4c9wA-3tqmA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq6 PUTATIVE ARSENICAL
PUMP-DRIVING ATPASE

(Methanothermobacter
thermautotrophicus) 		PF02374
(ArsA_ATPase) 		5 PHE A  16
PHE A 144
VAL A 216
ASP A 137
GLN A 129
 None
 1.30A 4c9wA-3zq6A:
undetectable		 4c9wA-3zq6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3x EPA1P

([Candida]
glabrata) 		PF10528
(GLEYA) 		5 LEU A 207
PHE A 234
PHE A 252
VAL A 169
PHE A 248
 None
 1.40A 4c9wA-4a3xA:
undetectable		 4c9wA-4a3xA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amt RENIN

(Homo sapiens) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		5 LEU A 124
PHE A 162
MET A 157
VAL A 131
PHE A 167
 None
 1.37A 4c9wA-4amtA:
undetectable		 4c9wA-4amtA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4asl EPA1P

([Candida]
glabrata) 		PF10528
(GLEYA) 		5 LEU A 207
PHE A 234
PHE A 252
VAL A 169
PHE A 248
 None
 1.38A 4c9wA-4aslA:
undetectable		 4c9wA-4aslA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ed5 ELAV-LIKE PROTEIN 1

(Homo sapiens) 		PF00076
(RRM_1) 		5 LEU A 113
PHE A 126
PHE A 154
VAL A 122
PHE A 129
 None
 1.49A 4c9wA-4ed5A:
undetectable		 4c9wA-4ed5A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gaa MGC78867 PROTEIN

(Xenopus laevis) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		5 LEU A 286
ASN A 528
PHE A 334
ASP A 283
GLN A 495
 None
 1.34A 4c9wA-4gaaA:
undetectable		 4c9wA-4gaaA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gym GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Conexibacter
woesei) 		no annotation 5 PHE A  24
MET A  43
VAL A  51
ASP A 119
PHE A  23
 None
 1.44A 4c9wA-4gymA:
undetectable		 4c9wA-4gymA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jmo CYTOHESIN-2

(Homo sapiens) 		PF01369
(Sec7) 		5 LEU A 234
ASN A 139
PHE A 243
VAL A 192
GLN A 146
 None
None
JAF  A 301 ( 4.8A)
None
None
 1.17A 4c9wA-4jmoA:
undetectable		 4c9wA-4jmoA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		5 PHE A 400
PHE A 337
VAL A 404
PHE A 422
GLN A 499
 None
 1.47A 4c9wA-4kxbA:
undetectable		 4c9wA-4kxbA:
11.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n1u 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Homo sapiens) 		PF00293
(NUDIX) 		5 LEU A   9
PHE A 139
VAL A  83
TRP A 117
ASP A 120
 2GE  A 201 (-4.1A)
2GE  A 201 (-3.7A)
2GE  A 201 ( 4.8A)
2GE  A 201 (-3.9A)
2GE  A 201 (-2.8A)
 1.47A 4c9wA-4n1uA:
28.1		 4c9wA-4n1uA:
98.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4n1u 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Homo sapiens) 		PF00293
(NUDIX) 		12 TYR A   7
LEU A   9
ASN A  33
PHE A  72
PHE A  74
MET A  81
VAL A  83
TRP A 117
ASP A 119
ASP A 120
PHE A 139
GLN A 142
 2GE  A 201 ( 4.7A)
2GE  A 201 (-4.1A)
2GE  A 201 (-3.1A)
2GE  A 201 (-3.3A)
2GE  A 201 (-4.8A)
2GE  A 201 ( 4.3A)
2GE  A 201 ( 4.8A)
2GE  A 201 (-3.9A)
2GE  A 201 (-2.8A)
2GE  A 201 (-2.8A)
2GE  A 201 (-3.7A)
None
 0.54A 4c9wA-4n1uA:
28.1		 4c9wA-4n1uA:
98.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4n HIV-1 GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		5 LEU A 288
PHE A 361
VAL A 286
TRP A 338
PHE A 391
 None
 1.25A 4c9wA-4r4nA:
undetectable		 4c9wA-4r4nA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcp NEMATODE FATTY ACID
RETINOID BINDING
PROTEIN

(Necator
americanus) 		PF05823
(Gp-FAR-1) 		5 LEU A  13
PHE A 143
PHE A 132
VAL A 142
PHE A  84
 None
 1.31A 4c9wA-4xcpA:
undetectable		 4c9wA-4xcpA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z48 UNCHARACTERIZED
PROTEIN

(Desulfovibrio
piger) 		PF17131
(LolA_like) 		5 TYR A 172
LEU A 174
VAL A 193
ASP A 151
GLN A  44
 None
 1.30A 4c9wA-4z48A:
undetectable		 4c9wA-4z48A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN

(Escherichia
coli;
Pyrococcus
furiosus) 		PF13416
(SBP_bac_8) 		5 LEU A 442
PHE A 455
PHE A 608
VAL A 453
PHE A 463
 None
 1.48A 4c9wA-5azaA:
undetectable		 4c9wA-5azaA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chc DMSO REDUCTASE
FAMILY TYPE II
ENZYME,
MOLYBDOPTERIN
SUBUNIT

(Azospira oryzae) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		5 LEU A 560
PHE A 534
PHE A 153
VAL A 532
PHE A 619
 None
 1.39A 4c9wA-5chcA:
undetectable		 4c9wA-5chcA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		5 TYR A 894
LEU A 898
PHE A  41
MET A 101
PHE A 221
 None
 1.36A 4c9wA-5fdnA:
undetectable		 4c9wA-5fdnA:
10.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hzx NUDIX (NUCLEOSIDE
DIPHOSPHATE LINKED
MOIETY X)-TYPE MOTIF
1

(Danio rerio) 		PF00293
(NUDIX) 		10 LEU A   9
ASN A  33
PHE A  72
PHE A  74
MET A  81
VAL A  83
TRP A 117
ASP A 119
ASP A 120
PHE A 139
 2GE  A 201 (-4.0A)
2GE  A 201 ( 3.2A)
2GE  A 201 (-3.5A)
2GE  A 201 (-4.8A)
2GE  A 201 (-3.8A)
2GE  A 201 ( 4.9A)
2GE  A 201 (-3.9A)
2GE  A 201 (-2.8A)
2GE  A 201 (-2.9A)
2GE  A 201 ( 4.0A)
 0.63A 4c9wA-5hzxA:
27.9		 4c9wA-5hzxA:
62.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqk PEPTIDASE, PUTATIVE

(Plasmodium
falciparum) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		5 LEU A 569
PHE A 532
VAL A 522
ASP A 490
GLN A 574
 None
 1.41A 4c9wA-5jqkA:
undetectable		 4c9wA-5jqkA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m22 HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT

(Sphingomonas
sp. TTNP3) 		no annotation 5 PHE B  88
MET B  99
VAL B  97
ASP B  72
PHE B  84
 None
 1.17A 4c9wA-5m22B:
undetectable		 4c9wA-5m22B:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mze 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Mus musculus) 		no annotation 5 LEU A   9
ASN A  33
VAL A  83
TRP A 117
PHE A  74
 8DG  A 204 (-4.2A)
8DG  A 204 (-2.9A)
8DG  A 204 ( 4.9A)
8DG  A 204 (-3.9A)
None
 1.34A 4c9wA-5mzeA:
28.6		 4c9wA-5mzeA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mze 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Mus musculus) 		no annotation 11 TYR A   7
LEU A   9
ASN A  33
PHE A  72
MET A  81
VAL A  83
TRP A 117
ASP A 119
ASP A 120
PHE A 139
GLN A 142
 8DG  A 204 (-4.6A)
8DG  A 204 (-4.2A)
8DG  A 204 (-2.9A)
8DG  A 204 (-3.7A)
8DG  A 204 (-3.5A)
8DG  A 204 ( 4.9A)
8DG  A 204 (-3.9A)
8DG  A 204 (-2.6A)
8DG  A 204 (-2.7A)
None
None
 0.47A 4c9wA-5mzeA:
28.6		 4c9wA-5mzeA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mze 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Mus musculus) 		no annotation 11 TYR A   7
LEU A   9
ASN A  33
PHE A  72
PHE A  74
MET A  81
VAL A  83
TRP A 117
ASP A 119
ASP A 120
PHE A 139
 8DG  A 204 (-4.6A)
8DG  A 204 (-4.2A)
8DG  A 204 (-2.9A)
8DG  A 204 (-3.7A)
None
8DG  A 204 (-3.5A)
8DG  A 204 ( 4.9A)
8DG  A 204 (-3.9A)
8DG  A 204 (-2.6A)
8DG  A 204 (-2.7A)
None
 0.57A 4c9wA-5mzeA:
28.6		 4c9wA-5mzeA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mze 7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE

(Mus musculus) 		no annotation 5 TYR A   7
LEU A   9
TRP A 117
ASP A 119
GLN A 142
 8DG  A 204 (-4.6A)
8DG  A 204 (-4.2A)
8DG  A 204 (-3.9A)
8DG  A 204 (-2.6A)
None
 1.47A 4c9wA-5mzeA:
28.6		 4c9wA-5mzeA:
52.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf5 SM80.1 VICILIN

(Solanum
melongena) 		no annotation 5 ASN A 261
PHE A 227
PHE A 392
MET A 248
PHE A 220
 ACT  A 502 (-3.3A)
ACT  A 502 (-4.7A)
None
None
None
 1.30A 4c9wA-5vf5A:
undetectable		 4c9wA-5vf5A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vn3 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		5 LEU G 288
PHE G 361
VAL G 286
TRP G 338
PHE G 391
 None
 1.29A 4c9wA-5vn3G:
undetectable		 4c9wA-5vn3G:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 5 LEU A 863
PHE A 721
PHE A 684
VAL A 862
PHE A 679
 None
 1.27A 4c9wA-5wlhA:
undetectable		 4c9wA-5wlhA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 5 LEU A1349
PHE A1322
PHE A1325
MET A1353
ASP A1301
 None
 1.36A 4c9wA-5wtkA:
undetectable		 4c9wA-5wtkA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fls -

(-) 		no annotation 5 PHE A  87
PHE A  92
MET A 107
VAL A 105
PHE A  72
 None
 1.13A 4c9wA-6flsA:
undetectable		 4c9wA-6flsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g42 MINOR CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 5 LEU A 113
PHE A 154
PHE A 167
VAL A  71
PHE A 165
 None
 1.47A 4c9wA-6g42A:
undetectable		 4c9wA-6g42A:
20.92