SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9P_B_CAMB423_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bs0 | PROTEIN(8-AMINO-7-OXONANOATE SYNTHASE) (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | THR A 209GLY A 242VAL A 231ASP A 204VAL A 232 | None | 1.35A | 4c9pB-1bs0A:undetectable | 4c9pB-1bs0A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1col | COLICIN A (Escherichiacoli) |
PF01024(Colicin) | 5 | TYR A 125LEU A 178LEU A 179GLY A 176VAL A 167 | None | 1.23A | 4c9pB-1colA:0.0 | 4c9pB-1colA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 5 | TRP A 377THR A 65LEU A 404LEU A 398VAL A 287 | None | 1.29A | 4c9pB-1d2kA:0.0 | 4c9pB-1d2kA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fsu | N-ACETYLGALACTOSAMINE-4-SULFATASE (Homo sapiens) |
PF00884(Sulfatase) | 5 | THR A 368THR A 107LEU A 371GLY A 101VAL A 122 | None | 1.20A | 4c9pB-1fsuA:0.0 | 4c9pB-1fsuA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gso | PROTEIN (GLYCINAMIDERIBONUCLEOTIDESYNTHETASE) (Escherichiacoli) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | THR A 296THR A 37GLY A 9VAL A 5VAL A 30 | None | 1.35A | 4c9pB-1gsoA:0.0 | 4c9pB-1gsoA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hxi | PEROXISOME TARGETINGSIGNAL 1 RECEPTORPEX5 (Trypanosomabrucei) |
no annotation | 5 | THR A 392LEU A 360LEU A 357GLY A 356VAL A 375 | None | 1.25A | 4c9pB-1hxiA:undetectable | 4c9pB-1hxiA:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyl | HYPODERMA LINEATUMCOLLAGENASE (Hypodermalineatum) |
PF00089(Trypsin) | 5 | TRP A 41GLY A 76VAL A 65ASP A 34VAL A 66 | None | 1.20A | 4c9pB-1hylA:0.0 | 4c9pB-1hylA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n0w | DNA REPAIR PROTEINRAD51 HOMOLOG 1 (Homo sapiens) |
PF08423(Rad51) | 5 | THR A 298LEU A 109LEU A 113GLY A 116VAL A 264 | NoneNone MG A 401 (-4.2A) MG A 401 (-3.8A)None | 1.21A | 4c9pB-1n0wA:undetectable | 4c9pB-1n0wA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 5 | TYR A 183THR A 130LEU A 136VAL A 152VAL A 179 | SAH A1501 (-4.8A)SAH A1501 ( 3.6A)NoneNoneNone | 1.24A | 4c9pB-1s4dA:undetectable | 4c9pB-1s4dA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1s | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Escherichiacoli) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | THR A 332LEU A 127GLY A 131VAL A 374VAL A 377 | None | 1.31A | 4c9pB-1t1sA:0.0 | 4c9pB-1t1sA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umg | 385AA LONG CONSERVEDHYPOTHETICAL PROTEIN (Sulfurisphaeratokodaii) |
PF01950(FBPase_3) | 5 | THR A 49LEU A 292LEU A 293GLY A 294VAL A 8 | None | 1.18A | 4c9pB-1umgA:undetectable | 4c9pB-1umgA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v8b | ADENOSYLHOMOCYSTEINASE (Plasmodiumfalciparum) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 251LEU A 384LEU A 390GLY A 341VAL A 260 | None | 1.22A | 4c9pB-1v8bA:undetectable | 4c9pB-1v8bA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 398LEU A 401GLY A 402VAL A 369VAL A 366 | None | 1.18A | 4c9pB-1xb7A:undetectable | 4c9pB-1xb7A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y1p | ALDEHYDE REDUCTASEII (Sporidiobolussalmonicolor) |
PF01370(Epimerase) | 5 | THR A 312LEU A 316LEU A 319GLY A 326VAL A 248 | None | 1.28A | 4c9pB-1y1pA:undetectable | 4c9pB-1y1pA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7d | ORNITHINEAMINOTRANSFERASE (Plasmodiumyoelii) |
PF00202(Aminotran_3) | 5 | THR A 385THR A 381LEU A 348GLY A 203VAL A 377 | None | 1.22A | 4c9pB-1z7dA:undetectable | 4c9pB-1z7dA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bpq | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 5 | LEU A 242LEU A 218GLY A 217VAL A 131VAL A 126 | None | 1.35A | 4c9pB-2bpqA:undetectable | 4c9pB-2bpqA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7u | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Thermusthermophilus) |
PF00202(Aminotran_3) | 5 | TRP A 394LEU A 417LEU A 420VAL A 350VAL A 359 | None | 1.33A | 4c9pB-2e7uA:undetectable | 4c9pB-2e7uA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipc | PREPROTEINTRANSLOCASE SECASUBUNIT (Thermusthermophilus) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 5 | LEU A 111GLY A 88VAL A 24ASP A 82VAL A 27 | None | 1.36A | 4c9pB-2ipcA:undetectable | 4c9pB-2ipcA:18.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | TYR A 96THR A 101LEU A 244GLY A 248VAL A 295 | CAM A 502 (-4.5A)HEM A 501 (-2.9A)HEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-4.6A) | 1.17A | 4c9pB-2m56A:57.6 | 4c9pB-2m56A:44.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 8 | TYR A 96THR A 101THR A 185LEU A 244GLY A 248VAL A 295ASP A 297VAL A 396 | CAM A 502 (-4.5A)HEM A 501 (-2.9A)NoneHEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-4.6A)HEM A 501 (-2.8A)None | 0.69A | 4c9pB-2m56A:57.6 | 4c9pB-2m56A:44.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oga | TRANSAMINASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 5 | THR A 206LEU A 218GLY A 77VAL A 162VAL A 184 | None | 1.17A | 4c9pB-2ogaA:undetectable | 4c9pB-2ogaA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3j | VP4 (Rotavirus A) |
PF00426(VP4_haemagglut) | 5 | THR A 191THR A 176LEU A 103GLY A 95VAL A 167 | None | 1.17A | 4c9pB-2p3jA:undetectable | 4c9pB-2p3jA:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbi | REGULATOR OFG-PROTEIN SIGNALING9GUANINENUCLEOTIDE-BINDINGPROTEIN SUBUNIT BETA5 (Mus musculus;Mus musculus) |
PF00610(DEP)PF00615(RGS)PF00631(G-gamma)PF00400(WD40) | 5 | TYR B 155THR A 209LEU B 199GLY B 216ASP B 174 | None | 1.35A | 4c9pB-2pbiB:undetectable | 4c9pB-2pbiB:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfy | PUTATIVE EXPORTEDPROTEIN (Bordetellapertussis) |
PF03480(DctP) | 5 | THR A 99LEU A 295LEU A 296ASP A 80VAL A 82 | None | 1.27A | 4c9pB-2pfyA:undetectable | 4c9pB-2pfyA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu0 | PHYTASE (Klebsiellapneumoniae) |
PF00328(His_Phos_2) | 5 | THR A 104GLY A 58VAL A 65ASP A 110VAL A 64 | None | 1.05A | 4c9pB-2wu0A:undetectable | 4c9pB-2wu0A:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg8 | DNA-3-METHYLADENINEGLYCOSIDASE II,PUTATIVE (Deinococcusradiodurans) |
PF00730(HhH-GPD) | 5 | THR A 197GLY A 183VAL A 41ASP A 39VAL A 45 | NoneNoneGOL A1228 (-4.2A)NoneNone | 1.26A | 4c9pB-2yg8A:undetectable | 4c9pB-2yg8A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwv | PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE (Thermusthermophilus) |
PF05175(MTS) | 5 | LEU A 220LEU A 223VAL A 258ASP A 239VAL A 237 | NoneNoneNoneSAH A 376 ( 4.2A)None | 1.21A | 4c9pB-2zwvA:undetectable | 4c9pB-2zwvA:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asa | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydiatrachomatis) |
PF00155(Aminotran_1_2) | 5 | TRP A 247THR A 207LEU A 292LEU A 289GLY A 288 | None | 0.92A | 4c9pB-3asaA:undetectable | 4c9pB-3asaA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3d | PUTATIVE MORPHINEDEHYDROGENASE (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 5 | THR A 50LEU A 107LEU A 105GLY A 61VAL A 24 | None | 1.13A | 4c9pB-3b3dA:undetectable | 4c9pB-3b3dA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn3 | INTERCELLULARADHESION MOLECULE 5 (Homo sapiens) |
PF03921(ICAM_N) | 5 | THR B 45THR B 38LEU B 52LEU B 36GLY B 35 | None | 1.32A | 4c9pB-3bn3B:undetectable | 4c9pB-3bn3B:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 269LEU A 402LEU A 408GLY A 359VAL A 278 | None | 1.21A | 4c9pB-3ce6A:undetectable | 4c9pB-3ce6A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9t | L-TYROSINEDECARBOXYLASE MFNA (Methanocaldococcusjannaschii) |
PF00282(Pyridoxal_deC) | 5 | LEU A 99LEU A 102GLY A 138ASP A 206VAL A 127 | NoneNoneNonePLP A 500 (-2.6A)None | 1.29A | 4c9pB-3f9tA:undetectable | 4c9pB-3f9tA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fha | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Glutamicibacterprotophormiae) |
PF03644(Glyco_hydro_85) | 5 | TRP A 282LEU A 55LEU A 296GLY A 297VAL A 271 | None | 1.28A | 4c9pB-3fhaA:undetectable | 4c9pB-3fhaA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 274LEU A 191GLY A 226VAL A 240VAL A 217 | None | 1.25A | 4c9pB-3g1uA:undetectable | 4c9pB-3g1uA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jq3 | LOMBRICINE KINASE (Urechis caupo) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | THR A 120LEU A 244LEU A 98GLY A 241VAL A 337 | None | 1.28A | 4c9pB-3jq3A:undetectable | 4c9pB-3jq3A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwt | NUCLEOPROTEIN (Lassamammarenavirus) |
PF00843(Arena_nucleocap)PF17290(Arena_ncap_C) | 5 | THR A 324LEU A 182GLY A 243VAL A 50VAL A 47 | None | 1.26A | 4c9pB-3mwtA:undetectable | 4c9pB-3mwtA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndn | O-SUCCINYLHOMOSERINESULFHYDRYLASE (Mycobacteriumtuberculosis) |
PF01053(Cys_Met_Meta_PP) | 5 | THR A 181THR A 166LEU A 193GLY A 205ASP A 176 | None | 1.05A | 4c9pB-3ndnA:undetectable | 4c9pB-3ndnA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 324LEU A 241GLY A 276VAL A 290VAL A 267 | None | 1.27A | 4c9pB-3oneA:undetectable | 4c9pB-3oneA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3piq | HUMAN MONOCLONALANTIBODY 2909 FABHEAVY CHAIN (Homo sapiens) |
no annotation | 5 | THR H 165LEU H 124GLY H 139VAL H 198VAL H 152 | None | 1.34A | 4c9pB-3piqH:undetectable | 4c9pB-3piqH:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rfy | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECYP38, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00160(Pro_isomerase) | 5 | THR A 401LEU A 262VAL A 422ASP A 242VAL A 421 | None | 1.11A | 4c9pB-3rfyA:undetectable | 4c9pB-3rfyA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rnq | PROGRAMMED CELLDEATH 1 LIGAND 2 (Mus musculus) |
PF08205(C2-set_2) | 5 | TYR B 123LEU B 173GLY B 172VAL B 119VAL B 34 | None | 1.07A | 4c9pB-3rnqB:undetectable | 4c9pB-3rnqB:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sh5 | LG3 PEPTIDE (Homo sapiens) |
PF00054(Laminin_G_1) | 5 | THR A 40LEU A 73LEU A 68GLY A 67VAL A 160 | None | 1.10A | 4c9pB-3sh5A:undetectable | 4c9pB-3sh5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t4c | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE 1 (Burkholderiaambifaria) |
PF00793(DAHP_synth_1) | 5 | TYR A 49THR A 29THR A 89LEU A 76GLY A 72 | None | 0.98A | 4c9pB-3t4cA:undetectable | 4c9pB-3t4cA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5q | NUCLEOPROTEIN (Mopeia Lassavirusreassortant 29) |
PF00843(Arena_nucleocap) | 5 | THR A 324LEU A 182GLY A 243VAL A 50VAL A 47 | None | 1.31A | 4c9pB-3t5qA:undetectable | 4c9pB-3t5qA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw3 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Burkholderiathailandensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 350LEU A 146LEU A 143GLY A 144VAL A 308 | None | 1.36A | 4c9pB-3uw3A:undetectable | 4c9pB-3uw3A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v57 | PHYCOERYTHRIN ALPHASUBUNIT (Porphyridiumpurpureum) |
PF00502(Phycobilisome) | 5 | THR A 134LEU A 159LEU A 156VAL A 52VAL A 51 | NoneNoneNoneNonePEB A 202 (-4.7A) | 1.25A | 4c9pB-3v57A:undetectable | 4c9pB-3v57A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9a | PUTATIVEUNCHARACTERIZEDPROTEIN (Coprinopsiscinerea) |
no annotation | 5 | TYR A 179LEU A 144GLY A 156VAL A 202VAL A 203 | None | 1.08A | 4c9pB-3w9aA:undetectable | 4c9pB-3w9aA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bms | ALCLOHOLDEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE (Ralstonia sp.DSMZ 6428) |
PF13561(adh_short_C2) | 5 | THR A 135THR A 118GLY A 13VAL A 110VAL A 61 | NAP A1250 (-4.1A)NoneNAP A1250 (-3.1A)NAP A1250 (-4.9A)NAP A1250 (-3.7A) | 1.35A | 4c9pB-4bmsA:undetectable | 4c9pB-4bmsA:21.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 6 | TRP A 89TYR A 98THR A 103LEU A 252GLY A 256VAL A 404 | NoneNoneGOL A1419 (-3.8A)HEM A1418 (-4.0A)HEM A1418 (-3.8A)GOL A1419 (-3.5A) | 1.26A | 4c9pB-4c9mA:70.9 | 4c9pB-4c9mA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 10 | TRP A 89TYR A 98THR A 103THR A 187LEU A 252LEU A 255GLY A 256VAL A 303ASP A 305VAL A 404 | NoneNoneGOL A1419 (-3.8A)NoneHEM A1418 (-4.0A)GOL A1419 ( 4.9A)HEM A1418 (-3.8A)GOL A1419 (-3.9A)HEM A1418 (-2.7A)GOL A1419 (-3.5A) | 0.26A | 4c9pB-4c9mA:70.9 | 4c9pB-4c9mA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | THR A 101LEU A 250GLY A 254VAL A 301VAL A 402 | HEM A 501 ( 4.8A)HEM A 501 (-4.3A)PEG A 502 (-3.8A)PEG A 502 ( 4.5A)None | 0.66A | 4c9pB-4dxyA:55.2 | 4c9pB-4dxyA:61.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | THR A 101THR A 185LEU A 250LEU A 253GLY A 254 | HEM A 501 ( 4.8A)NoneHEM A 501 (-4.3A)NonePEG A 502 (-3.8A) | 1.15A | 4c9pB-4dxyA:55.2 | 4c9pB-4dxyA:61.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hac | MEVALONATE KINASE (Methanosarcinamazei) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | THR A 291THR A 257LEU A 31LEU A 92GLY A 8 | None | 1.23A | 4c9pB-4hacA:undetectable | 4c9pB-4hacA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k9q | BENZOYLFORMATEDECARBOXYLASE (Polynucleobacternecessarius) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | THR A 441THR A 19LEU A 412GLY A 409VAL A 65 | None | 1.27A | 4c9pB-4k9qA:undetectable | 4c9pB-4k9qA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kdw | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 5 | THR A 56GLY A 32VAL A 83ASP A 43VAL A 45 | NoneNoneNoneGOL A 208 (-4.4A)None | 1.21A | 4c9pB-4kdwA:undetectable | 4c9pB-4kdwA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke4 | HYDROXYCINNAMOYL-COA:SHIKIMATEHYDROXYCINNAMOYLTRANSFERASE (Sorghum bicolor) |
PF02458(Transferase) | 5 | LEU A 295LEU A 381GLY A 382VAL A 417VAL A 429 | None | 1.36A | 4c9pB-4ke4A:undetectable | 4c9pB-4ke4A:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lk2 | PRE-MRNA-PROCESSINGATP-DEPENDENT RNAHELICASE PRP5 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | THR A 329THR A 435LEU A 404LEU A 396VAL A 436 | None | 1.25A | 4c9pB-4lk2A:undetectable | 4c9pB-4lk2A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0k | ADENINEPHOSPHORIBOSYLTRANSFERASE (Rhodothermusmarinus) |
PF00156(Pribosyltran) | 5 | THR A 173LEU A 165GLY A 161VAL A 126ASP A 124 | NoneNoneNoneAMP A 300 (-3.9A)AMP A 300 (-3.0A) | 1.27A | 4c9pB-4m0kA:undetectable | 4c9pB-4m0kA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfi | SN-GLYCEROL-3-PHOSPHATE ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN USPB (Mycobacteriumtuberculosis) |
PF13416(SBP_bac_8) | 5 | THR A 331LEU A 99LEU A 309GLY A 308VAL A 348 | None | 1.04A | 4c9pB-4mfiA:undetectable | 4c9pB-4mfiA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 5 | THR A 234LEU A 230GLY A 199VAL A 371VAL A 374 | None | 1.35A | 4c9pB-4mnrA:undetectable | 4c9pB-4mnrA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n2c | PROTEIN-ARGININEDEIMINASE TYPE-2 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 5 | THR A 27LEU A 9GLY A 110VAL A 50VAL A 79 | None | 1.12A | 4c9pB-4n2cA:undetectable | 4c9pB-4n2cA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n91 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Anaerococcusprevotii) |
PF03480(DctP) | 5 | THR A 147GLY A 48VAL A 93ASP A 242VAL A 244 | NoneNoneNoneGCU A 401 ( 2.7A)None | 0.83A | 4c9pB-4n91A:undetectable | 4c9pB-4n91A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nh0 | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 5 | THR A1310LEU A1271GLY A1270VAL A1102ASP A1095 | ATP A1404 (-4.4A)NoneNoneNoneNone | 1.27A | 4c9pB-4nh0A:undetectable | 4c9pB-4nh0A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oh0 | BETA-LACTAMASEOXA-58 (Acinetobacterbaumannii) |
PF00905(Transpeptidase) | 5 | THR A 59LEU A 274GLY A 275VAL A 238VAL A 246 | None | 1.03A | 4c9pB-4oh0A:undetectable | 4c9pB-4oh0A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okr | MICRONEMAL PROTEINMIC2 (Toxoplasmagondii) |
PF00090(TSP_1)PF00092(VWA) | 5 | THR A 155LEU A 80GLY A 160VAL A 198ASP A 194 | None | 1.30A | 4c9pB-4okrA:undetectable | 4c9pB-4okrA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 56GLY A 32VAL A 83ASP A 43VAL A 45 | NoneNoneNone CA A 510 ( 4.9A)None | 1.21A | 4c9pB-4p99A:undetectable | 4c9pB-4p99A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 160GLY A 136VAL A 187ASP A 147VAL A 149 | NoneNoneNone CA A 507 ( 4.9A)None | 1.18A | 4c9pB-4p99A:undetectable | 4c9pB-4p99A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 264GLY A 240VAL A 291ASP A 251VAL A 253 | NoneNoneNone CA A 520 ( 4.7A)None | 1.19A | 4c9pB-4p99A:undetectable | 4c9pB-4p99A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 368GLY A 344VAL A 395ASP A 355VAL A 357 | None | 1.20A | 4c9pB-4p99A:undetectable | 4c9pB-4p99A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbu | ZMAA (Bacillus cereus) |
PF00698(Acyl_transf_1) | 5 | THR A 382LEU A 98GLY A 190VAL A 258VAL A 352 | None | 1.21A | 4c9pB-4qbuA:undetectable | 4c9pB-4qbuA:23.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdk | MAGNESIUM-PROTOPORPHYRINO-METHYLTRANSFERASE (Synechocystissp. PCC 6803) |
PF07109(Mg-por_mtran_C) | 5 | THR A 130LEU A 55VAL A 87ASP A 68VAL A 66 | None | 1.25A | 4c9pB-4qdkA:undetectable | 4c9pB-4qdkA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r33 | NOSL (Streptomycesactuosus) |
PF06968(BATS) | 5 | TYR A 242LEU A 187GLY A 158ASP A 195VAL A 172 | None | 1.07A | 4c9pB-4r33A:undetectable | 4c9pB-4r33A:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | THR A 708THR A 564LEU A 580LEU A 577GLY A 576 | None | 1.21A | 4c9pB-4rbnA:undetectable | 4c9pB-4rbnA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ut1 | FLAGELLARHOOK-ASSOCIATEDPROTEIN (Burkholderiapseudomallei) |
PF06429(Flg_bbr_C) | 5 | THR A 166LEU A 278LEU A 283GLY A 284VAL A 159 | EDO A1639 (-3.2A)NoneNoneNoneNone | 1.32A | 4c9pB-4ut1A:undetectable | 4c9pB-4ut1A:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8j | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | THR A 264GLY A 479VAL A 487ASP A 497VAL A 499 | None | 1.19A | 4c9pB-4w8jA:undetectable | 4c9pB-4w8jA:15.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrn | MALTOSE-BINDINGPERIPLASMICPROTEIN,UROMODULIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 5 | THR A 589LEU A 601LEU A 602GLY A 641VAL A 637 | None | 1.25A | 4c9pB-4wrnA:undetectable | 4c9pB-4wrnA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3j | PUTATIVEQUINONE-OXIDOREDUCTASE HOMOLOG,CHLOROPLASTIC (Arabidopsisthaliana) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | THR A 43THR A 116LEU A 40LEU A 38GLY A 75 | None | 1.33A | 4c9pB-5a3jA:undetectable | 4c9pB-5a3jA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az3 | ABC-TYPETRANSPORTER,PERIPLASMICCOMPONENT (Corynebacteriumglutamicum) |
PF01497(Peripla_BP_2) | 5 | THR A 69THR A 108LEU A 210GLY A 207VAL A 201 | None | 1.35A | 4c9pB-5az3A:undetectable | 4c9pB-5az3A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | LEU A 26LEU A 29GLY A 30ASP A 43VAL A 107 | NoneNoneNoneSAH A 301 ( 4.5A)None | 1.17A | 4c9pB-5bp7A:undetectable | 4c9pB-5bp7A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | LEU A 26LEU A 29GLY A 30VAL A 41VAL A 107 | None | 0.80A | 4c9pB-5bp7A:undetectable | 4c9pB-5bp7A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c3l | NANOBODY NB15 (Camelusdromedarius) |
PF07686(V-set) | 5 | LEU D 79LEU D 81VAL D 47ASP D 50VAL D 48 | None | 1.25A | 4c9pB-5c3lD:undetectable | 4c9pB-5c3lD:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfa | BETA-GALACTOSIDASE (Geobacillusstearothermophilus) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | THR A 48THR A 10LEU A 359LEU A 320VAL A 406 | None | 1.16A | 4c9pB-5dfaA:undetectable | 4c9pB-5dfaA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmn | HOMOCYSTEINES-METHYLTRANSFERASE (Escherichiacoli) |
PF02574(S-methyl_trans) | 5 | THR A 246LEU A 239LEU A 250GLY A 226VAL A 213 | None | 1.35A | 4c9pB-5dmnA:undetectable | 4c9pB-5dmnA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 25LEU A 28GLY A 29ASP A 42VAL A 106 | NoneNoneNoneSAH A 301 ( 4.5A)None | 1.20A | 4c9pB-5epeA:undetectable | 4c9pB-5epeA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 25LEU A 28GLY A 29VAL A 40VAL A 106 | None | 0.78A | 4c9pB-5epeA:undetectable | 4c9pB-5epeA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffp | IMMUNITY 23 FAMILYPROTEIN (Burkholderiadolosa) |
PF15593(Imm42) | 5 | LEU A 105LEU A 29GLY A 30VAL A 148VAL A 151 | None | 1.33A | 4c9pB-5ffpA:undetectable | 4c9pB-5ffpA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irb | RTX-ADHESIN (Marinomonasprimoryensis) |
no annotation | 5 | THR A 446GLY A 422VAL A 473ASP A 433VAL A 435 | None | 1.22A | 4c9pB-5irbA:undetectable | 4c9pB-5irbA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw7 | RIBOSOME BIOGENESISPROTEINTSR1,RIBOSOMEBIOGENESIS PROTEINTSR1 (Saccharomycescerevisiae) |
PF04950(RIBIOP_C)PF08142(AARP2CN) | 5 | THR A 663LEU A 585LEU A 584GLY A 583VAL A 620 | None | 1.33A | 4c9pB-5iw7A:undetectable | 4c9pB-5iw7A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j7z | PUTATIVE SECRETEDENDOGLYCOSYLCERAMIDASE (Rhodococcushoagii) |
PF00150(Cellulase) | 5 | THR A 71LEU A 66LEU A 112VAL A 88VAL A 126 | None | 1.31A | 4c9pB-5j7zA:undetectable | 4c9pB-5j7zA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxm | PRIB (Streptomycessp. RM-5-8) |
PF11991(Trp_DMAT) | 5 | THR A 91LEU A 35GLY A 36VAL A 111VAL A 93 | None | 0.84A | 4c9pB-5jxmA:undetectable | 4c9pB-5jxmA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9x | TRYPTOPHAN SYNTHASEALPHA CHAIN (Legionellapneumophila) |
PF00290(Trp_syntA) | 5 | THR A 33LEU A 99LEU A 50GLY A 51ASP A 80 | None | 1.08A | 4c9pB-5k9xA:undetectable | 4c9pB-5k9xA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kar | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3B (Mus musculus) |
PF00149(Metallophos) | 5 | TYR A 151LEU A 132GLY A 133VAL A 108VAL A 112 | None | 1.34A | 4c9pB-5karA:undetectable | 4c9pB-5karA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kju | SHIKIMATEO-HYDROXYCINNAMOYLTRANSFERASE (Arabidopsisthaliana) |
PF02458(Transferase) | 5 | LEU A 279LEU A 366GLY A 367VAL A 402VAL A 414 | None | 1.25A | 4c9pB-5kjuA:undetectable | 4c9pB-5kjuA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lae | PEROXISOMALN(1)-ACETYL-SPERMINE/SPERMIDINEOXIDASE,PEROXISOMALN(1)-ACETYL-SPERMINE/SPERMIDINE OXIDASE (Mus musculus) |
PF01593(Amino_oxidase) | 5 | THR A 222THR A 279GLY A 19VAL A 35VAL A 10 | None | 1.18A | 4c9pB-5laeA:undetectable | 4c9pB-5laeA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqm | GLYCOSYL HYDROLASESFAMILY 2, SUGARBINDING DOMAIN (Bacteroidesthetaiotaomicron) |
PF17132(Glyco_hydro_106) | 5 | TYR A 954LEU A 949LEU A1096VAL A1021VAL A1019 | None | 1.30A | 4c9pB-5mqmA:undetectable | 4c9pB-5mqmA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5umx | GLYOXALASE/BLEOMYCINRESISANCEPROTEIN/DIOXYGENASE (Streptomycessp. CB03234) |
no annotation | 5 | LEU A 73LEU A 116GLY A 115VAL A 90VAL A 92 | None | 1.36A | 4c9pB-5umxA:undetectable | 4c9pB-5umxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vev | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Neisseriagonorrhoeae) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | THR A 294THR A 37GLY A 9VAL A 5VAL A 30 | None | 1.36A | 4c9pB-5vevA:undetectable | 4c9pB-5vevA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmk | BIFUNCTIONAL PROTEINGLMU (Acinetobacterbaumannii) |
PF00132(Hexapep)PF12804(NTP_transf_3)PF14602(Hexapep_2) | 5 | TRP A 70THR A 62THR A 50LEU A 33GLY A 34 | None | 1.31A | 4c9pB-5vmkA:undetectable | 4c9pB-5vmkA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xw3 | O-ACETYLSERINE LYASE (Bacillusanthracis) |
PF00291(PALP) | 5 | THR A 284THR A 288LEU A 30VAL A 200VAL A 174 | None | 1.23A | 4c9pB-5xw3A:undetectable | 4c9pB-5xw3A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cet | GATOR COMPLEXPROTEIN NPRL2 (Homo sapiens) |
no annotation | 5 | TYR N 43THR N 24LEU N 50VAL N 88ASP N 38 | None | 1.35A | 4c9pB-6cetN:undetectable | 4c9pB-6cetN:undetectable |