SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9P_A_CAMA423_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1col COLICIN A

(Escherichia
coli) 		PF01024
(Colicin) 		5 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.23A 4c9pA-1colA:
0.0		 4c9pA-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2k CHITINASE 1

(Coccidioides
immitis) 		PF00704
(Glyco_hydro_18) 		5 TRP A 377
THR A  65
LEU A 404
LEU A 398
VAL A 287
 None
 1.31A 4c9pA-1d2kA:
0.0		 4c9pA-1d2kA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek6 UDP-GALACTOSE
4-EPIMERASE

(Homo sapiens) 		PF16363
(GDP_Man_Dehyd) 		5 LEU A 247
LEU A 269
GLY A 250
VAL A 128
VAL A 181
 None
 1.31A 4c9pA-1ek6A:
undetectable		 4c9pA-1ek6A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fsu N-ACETYLGALACTOSAMIN
E-4-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase) 		5 THR A 368
THR A 107
LEU A 371
GLY A 101
VAL A 122
 None
 1.23A 4c9pA-1fsuA:
undetectable		 4c9pA-1fsuA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gso PROTEIN (GLYCINAMIDE
RIBONUCLEOTIDE
SYNTHETASE)

(Escherichia
coli) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		5 THR A 296
THR A  37
GLY A   9
VAL A   5
VAL A  30
 None
 1.32A 4c9pA-1gsoA:
0.0		 4c9pA-1gsoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hxi PEROXISOME TARGETING
SIGNAL 1 RECEPTOR
PEX5

(Trypanosoma
brucei) 		no annotation 5 THR A 392
LEU A 360
LEU A 357
GLY A 356
VAL A 375
 None
 1.27A 4c9pA-1hxiA:
undetectable		 4c9pA-1hxiA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n0w DNA REPAIR PROTEIN
RAD51 HOMOLOG 1

(Homo sapiens) 		PF08423
(Rad51) 		5 THR A 298
LEU A 109
LEU A 113
GLY A 116
VAL A 264
 None
None
MG  A 401 (-4.2A)
MG  A 401 (-3.8A)
None
 1.17A 4c9pA-1n0wA:
0.0		 4c9pA-1n0wA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4d UROPORPHYRIN-III
C-METHYLTRANSFERASE

(Pseudomonas
denitrificans
(nomen
rejiciendum)) 		PF00590
(TP_methylase) 		5 TYR A 183
THR A 130
LEU A 136
VAL A 152
VAL A 179
 SAH  A1501 (-4.8A)
SAH  A1501 ( 3.6A)
None
None
None
 1.24A 4c9pA-1s4dA:
undetectable		 4c9pA-1s4dA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umg 385AA LONG CONSERVED
HYPOTHETICAL PROTEIN

(Sulfurisphaera
tokodaii) 		PF01950
(FBPase_3) 		5 THR A  49
LEU A 292
LEU A 293
GLY A 294
VAL A   8
 None
 1.21A 4c9pA-1umgA:
0.0		 4c9pA-1umgA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6c ALKALINE SERINE
PROTEASE

(Pseudoalteromonas
sp. AS-11) 		PF00082
(Peptidase_S8)
PF02225
(PA) 		5 THR A 352
LEU A 257
LEU A 278
VAL A 231
VAL A 336
 None
 1.40A 4c9pA-1v6cA:
0.0		 4c9pA-1v6cA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 THR A 251
LEU A 384
LEU A 390
GLY A 341
VAL A 260
 None
 1.17A 4c9pA-1v8bA:
undetectable		 4c9pA-1v8bA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xb7 STEROID HORMONE
RECEPTOR ERR1

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 LEU A 398
LEU A 401
GLY A 402
VAL A 369
VAL A 366
 None
 1.16A 4c9pA-1xb7A:
undetectable		 4c9pA-1xb7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvx YFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		5 THR A 253
LEU A  60
GLY A 233
VAL A 271
VAL A  87
 None
 1.38A 4c9pA-1xvxA:
undetectable		 4c9pA-1xvxA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvy SFUA

(Yersinia
enterocolitica) 		PF13343
(SBP_bac_6) 		5 THR A 250
LEU A  57
GLY A 230
VAL A 268
VAL A  84
 None
 1.40A 4c9pA-1xvyA:
undetectable		 4c9pA-1xvyA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y1p ALDEHYDE REDUCTASE
II

(Sporidiobolus
salmonicolor) 		PF01370
(Epimerase) 		5 THR A 312
LEU A 316
LEU A 319
GLY A 326
VAL A 248
 None
 1.26A 4c9pA-1y1pA:
undetectable		 4c9pA-1y1pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7d ORNITHINE
AMINOTRANSFERASE

(Plasmodium
yoelii) 		PF00202
(Aminotran_3) 		5 THR A 385
THR A 381
LEU A 348
GLY A 203
VAL A 377
 None
 1.21A 4c9pA-1z7dA:
undetectable		 4c9pA-1z7dA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7u GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Thermus
thermophilus) 		PF00202
(Aminotran_3) 		5 TRP A 394
LEU A 417
LEU A 420
VAL A 350
VAL A 359
 None
 1.33A 4c9pA-2e7uA:
undetectable		 4c9pA-2e7uA:
24.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 TYR A  96
THR A 101
LEU A 244
GLY A 248
VAL A 295
 CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-4.6A)
 1.15A 4c9pA-2m56A:
57.8		 4c9pA-2m56A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		7 TYR A  96
THR A 101
THR A 185
LEU A 244
GLY A 248
VAL A 295
VAL A 396
 CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
None
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-4.6A)
None
 0.56A 4c9pA-2m56A:
57.8		 4c9pA-2m56A:
44.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oga TRANSAMINASE

(Streptomyces
venezuelae) 		PF01041
(DegT_DnrJ_EryC1) 		5 THR A 206
LEU A 218
GLY A  77
VAL A 162
VAL A 184
 None
 1.22A 4c9pA-2ogaA:
undetectable		 4c9pA-2ogaA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3j VP4

(Rotavirus A) 		PF00426
(VP4_haemagglut) 		5 THR A 191
THR A 176
LEU A 103
GLY A  95
VAL A 167
 None
 1.21A 4c9pA-2p3jA:
undetectable		 4c9pA-2p3jA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rq6 ATP SYNTHASE EPSILON
CHAIN

(Thermosynechococcus
elongatus) 		PF00401
(ATP-synt_DE)
PF02823
(ATP-synt_DE_N) 		5 THR A  42
LEU A  24
LEU A  31
GLY A  32
VAL A  69
 None
 1.21A 4c9pA-2rq6A:
undetectable		 4c9pA-2rq6A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9q ROUNDABOUT HOMOLOG 1

(Homo sapiens) 		PF07679
(I-set)
PF13927
(Ig_3) 		5 THR A 110
THR A  86
LEU A 121
LEU A 122
GLY A 125
 None
 1.39A 4c9pA-2v9qA:
undetectable		 4c9pA-2v9qA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster) 		PF03159
(XRN_N) 		5 TYR A 439
THR A 466
LEU A 293
GLY A 286
VAL A 446
 None
 1.36A 4c9pA-2y35A:
undetectable		 4c9pA-2y35A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1q ACYL-COA
DEHYDROGENASE

(Thermus
thermophilus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		5 THR A  39
LEU A  75
LEU A  74
VAL A  47
VAL A  43
 None
 1.40A 4c9pA-2z1qA:
undetectable		 4c9pA-2z1qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		5 THR A 205
LEU A 383
LEU A 379
GLY A 352
VAL A 230
 None
 1.38A 4c9pA-3aoeA:
undetectable		 4c9pA-3aoeA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asa LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Chlamydia
trachomatis) 		PF00155
(Aminotran_1_2) 		5 TRP A 247
THR A 207
LEU A 292
LEU A 289
GLY A 288
 None
 0.82A 4c9pA-3asaA:
undetectable		 4c9pA-3asaA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b3d PUTATIVE MORPHINE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		5 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.11A 4c9pA-3b3dA:
undetectable		 4c9pA-3b3dA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn3 INTERCELLULAR
ADHESION MOLECULE 5

(Homo sapiens) 		PF03921
(ICAM_N) 		5 THR B  45
THR B  38
LEU B  52
LEU B  36
GLY B  35
 None
 1.31A 4c9pA-3bn3B:
undetectable		 4c9pA-3bn3B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dla GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		5 TYR A   7
THR A 276
LEU A 310
LEU A 166
VAL A 196
 None
 1.27A 4c9pA-3dlaA:
undetectable		 4c9pA-3dlaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Glutamicibacter
protophormiae) 		PF03644
(Glyco_hydro_85) 		5 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.25A 4c9pA-3fhaA:
undetectable		 4c9pA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1u ADENOSYLHOMOCYSTEINA
SE

(Leishmania
major) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 THR A 274
LEU A 191
GLY A 226
VAL A 240
VAL A 217
 None
 1.29A 4c9pA-3g1uA:
undetectable		 4c9pA-3g1uA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		5 TRP A 278
LEU A 400
GLY A 384
VAL A 282
VAL A 306
 None
 1.35A 4c9pA-3gwjA:
undetectable		 4c9pA-3gwjA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq3 LOMBRICINE KINASE

(Urechis caupo) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		5 THR A 120
LEU A 244
LEU A  98
GLY A 241
VAL A 337
 None
 1.28A 4c9pA-3jq3A:
undetectable		 4c9pA-3jq3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwn PHYCOERYTHRIN

(Phormidium
tenue) 		PF00502
(Phycobilisome) 		5 THR A1134
LEU A1159
LEU A1156
VAL A1052
VAL A1051
 None
None
None
None
CYC  A3002 ( 4.5A)
 1.26A 4c9pA-3mwnA:
undetectable		 4c9pA-3mwnA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwt NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF00843
(Arena_nucleocap)
PF17290
(Arena_ncap_C) 		5 THR A 324
LEU A 182
GLY A 243
VAL A  50
VAL A  47
 None
 1.28A 4c9pA-3mwtA:
undetectable		 4c9pA-3mwtA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noq THIJ/PFPI FAMILY
PROTEIN

(Pseudomonas
fluorescens) 		PF01965
(DJ-1_PfpI) 		5 THR A 120
LEU A 128
LEU A 131
GLY A 108
VAL A  74
 None
 1.26A 4c9pA-3noqA:
undetectable		 4c9pA-3noqA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 THR A 324
LEU A 241
GLY A 276
VAL A 290
VAL A 267
 None
 1.30A 4c9pA-3oneA:
undetectable		 4c9pA-3oneA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sh5 LG3 PEPTIDE

(Homo sapiens) 		PF00054
(Laminin_G_1) 		5 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.12A 4c9pA-3sh5A:
undetectable		 4c9pA-3sh5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4c 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE 1

(Burkholderia
ambifaria) 		PF00793
(DAHP_synth_1) 		5 TYR A  49
THR A  29
THR A  89
LEU A  76
GLY A  72
 None
 0.95A 4c9pA-3t4cA:
undetectable		 4c9pA-3t4cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5q NUCLEOPROTEIN

(Mopeia Lassa
virus
reassortant 29) 		PF00843
(Arena_nucleocap) 		5 THR A 324
LEU A 182
GLY A 243
VAL A  50
VAL A  47
 None
 1.31A 4c9pA-3t5qA:
undetectable		 4c9pA-3t5qA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Burkholderia
thailandensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		5 THR A 350
LEU A 146
LEU A 143
GLY A 144
VAL A 308
 None
 1.34A 4c9pA-3uw3A:
undetectable		 4c9pA-3uw3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v57 PHYCOERYTHRIN ALPHA
SUBUNIT

(Porphyridium
purpureum) 		PF00502
(Phycobilisome) 		5 THR A 134
LEU A 159
LEU A 156
VAL A  52
VAL A  51
 None
None
None
None
PEB  A 202 (-4.7A)
 1.26A 4c9pA-3v57A:
undetectable		 4c9pA-3v57A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN

(Coprinopsis
cinerea) 		no annotation 5 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.10A 4c9pA-3w9aA:
undetectable		 4c9pA-3w9aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvr PGM1

(Streptomyces
cirratus) 		no annotation 5 TYR A  50
LEU A 388
GLY A 396
VAL A 350
VAL A 346
 None
 1.37A 4c9pA-3wvrA:
undetectable		 4c9pA-3wvrA:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bms ALCLOHOL
DEHYDROGENASE/SHORT-
CHAIN DEHYDROGENASE

(Ralstonia sp.
DSMZ 6428) 		PF13561
(adh_short_C2) 		5 THR A 135
THR A 118
GLY A  13
VAL A 110
VAL A  61
 NAP  A1250 (-4.1A)
None
NAP  A1250 (-3.1A)
NAP  A1250 (-4.9A)
NAP  A1250 (-3.7A)
 1.36A 4c9pA-4bmsA:
undetectable		 4c9pA-4bmsA:
21.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		6 TRP A  89
TYR A  98
THR A 103
LEU A 252
GLY A 256
VAL A 404
 None
None
GOL  A1419 (-3.8A)
HEM  A1418 (-4.0A)
HEM  A1418 (-3.8A)
GOL  A1419 (-3.5A)
 1.22A 4c9pA-4c9mA:
72.5		 4c9pA-4c9mA:
99.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		9 TRP A  89
TYR A  98
THR A 103
THR A 187
LEU A 252
LEU A 255
GLY A 256
VAL A 303
VAL A 404
 None
None
GOL  A1419 (-3.8A)
None
HEM  A1418 (-4.0A)
GOL  A1419 ( 4.9A)
HEM  A1418 (-3.8A)
GOL  A1419 (-3.9A)
GOL  A1419 (-3.5A)
 0.17A 4c9pA-4c9mA:
72.5		 4c9pA-4c9mA:
99.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		5 THR A 101
LEU A 250
GLY A 254
VAL A 301
VAL A 402
 HEM  A 501 ( 4.8A)
HEM  A 501 (-4.3A)
PEG  A 502 (-3.8A)
PEG  A 502 ( 4.5A)
None
 0.69A 4c9pA-4dxyA:
55.7		 4c9pA-4dxyA:
61.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		5 THR A 101
THR A 185
LEU A 250
LEU A 253
GLY A 254
 HEM  A 501 ( 4.8A)
None
HEM  A 501 (-4.3A)
None
PEG  A 502 (-3.8A)
 1.13A 4c9pA-4dxyA:
55.7		 4c9pA-4dxyA:
61.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gj1 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)METHYLIDENEAM
INO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE

(Campylobacter
jejuni) 		PF00977
(His_biosynth) 		5 THR A   2
LEU A 241
LEU A 211
VAL A 184
VAL A 182
 None
 1.31A 4c9pA-4gj1A:
undetectable		 4c9pA-4gj1A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glr ANTI-PTAU HEAVY
CHAIN
ANTI-PTAU LIGHT
CHAIN

(Gallus gallus;
Gallus gallus) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		5 TYR H  91
THR H  89
LEU H  45
GLY H  44
VAL I  85
 None
 1.34A 4c9pA-4glrH:
undetectable		 4c9pA-4glrH:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1g MALTOSE BINDING
PROTEIN-CAKAR3 MOTOR
DOMAIN FUSION
PROTEIN

(Escherichia
coli;
Candida
albicans) 		PF00225
(Kinesin)
PF13416
(SBP_bac_8) 		5 THR A 654
THR A 641
LEU A 618
GLY A 619
VAL A 633
 None
 1.34A 4c9pA-4h1gA:
undetectable		 4c9pA-4h1gA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hac MEVALONATE KINASE

(Methanosarcina
mazei) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		5 THR A 291
THR A 257
LEU A  31
LEU A  92
GLY A   8
 None
 1.27A 4c9pA-4hacA:
undetectable		 4c9pA-4hacA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7b POLO-LIKE KINASE

(Danio rerio) 		PF00069
(Pkinase) 		5 THR A 146
THR A 229
LEU A 168
LEU A 165
GLY A 166
 None
 1.33A 4c9pA-4j7bA:
undetectable		 4c9pA-4j7bA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9q BENZOYLFORMATE
DECARBOXYLASE

(Polynucleobacter
necessarius) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 THR A 441
THR A  19
LEU A 412
GLY A 409
VAL A  65
 None
 1.29A 4c9pA-4k9qA:
undetectable		 4c9pA-4k9qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ke4 HYDROXYCINNAMOYL-COA
:SHIKIMATE
HYDROXYCINNAMOYL
TRANSFERASE

(Sorghum bicolor) 		PF02458
(Transferase) 		5 LEU A 295
LEU A 381
GLY A 382
VAL A 417
VAL A 429
 None
 1.37A 4c9pA-4ke4A:
undetectable		 4c9pA-4ke4A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhe THERMOSTABLE
MONOACYLGLYCEROL
LIPASE

(Bacillus sp.
H-257) 		PF12146
(Hydrolase_4) 		5 THR A 162
LEU A 167
LEU A 170
VAL A 198
VAL A 199
 None
 1.40A 4c9pA-4lheA:
undetectable		 4c9pA-4lheA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lk2 PRE-MRNA-PROCESSING
ATP-DEPENDENT RNA
HELICASE PRP5

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		5 THR A 329
THR A 435
LEU A 404
LEU A 396
VAL A 436
 None
 1.23A 4c9pA-4lk2A:
undetectable		 4c9pA-4lk2A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB

(Mycobacterium
tuberculosis) 		PF13416
(SBP_bac_8) 		5 THR A 331
LEU A  99
LEU A 309
GLY A 308
VAL A 348
 None
 1.03A 4c9pA-4mfiA:
undetectable		 4c9pA-4mfiA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnr PEPTIDOGLYCAN
GLYCOSYLTRANSFERASE

(Eggerthella
lenta) 		PF00905
(Transpeptidase) 		5 THR A 234
LEU A 230
GLY A 199
VAL A 371
VAL A 374
 None
 1.36A 4c9pA-4mnrA:
undetectable		 4c9pA-4mnrA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oh0 BETA-LACTAMASE
OXA-58

(Acinetobacter
baumannii) 		PF00905
(Transpeptidase) 		5 THR A  59
LEU A 274
GLY A 275
VAL A 238
VAL A 246
 None
 1.05A 4c9pA-4oh0A:
undetectable		 4c9pA-4oh0A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p49 ANTIBODY SCFV B8

(Gallus gallus) 		PF07686
(V-set) 		5 TYR A 216
THR A 214
LEU A 165
GLY A 164
VAL A  80
 None
 1.36A 4c9pA-4p49A:
undetectable		 4c9pA-4p49A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb9 ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN

(Mycolicibacterium
smegmatis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		5 TYR A 400
LEU A 398
GLY A 184
VAL A  79
VAL A 117
 None
 1.22A 4c9pA-4qb9A:
undetectable		 4c9pA-4qb9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbu ZMAA

(Bacillus cereus) 		PF00698
(Acyl_transf_1) 		5 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.19A 4c9pA-4qbuA:
undetectable		 4c9pA-4qbuA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		5 THR A 708
THR A 564
LEU A 580
LEU A 577
GLY A 576
 None
 1.17A 4c9pA-4rbnA:
undetectable		 4c9pA-4rbnA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rj9 C2 DOMAIN-CONTAINING
PROTEIN-LIKE

(Oryza sativa) 		PF00168
(C2) 		5 THR A  48
THR A  42
GLY A  16
VAL A  72
VAL A  31
 None
 1.15A 4c9pA-4rj9A:
undetectable		 4c9pA-4rj9A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udr GLUCOSE-METHANOL-CHO
LINE OXIDOREDUCTASE

(Methylovorus
sp. MP688) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		5 THR A 278
LEU A 237
GLY A 245
VAL A 233
VAL A 248
 None
None
None
FAD  A 700 (-4.0A)
None
 1.08A 4c9pA-4udrA:
undetectable		 4c9pA-4udrA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		5 THR A 589
LEU A 601
LEU A 602
GLY A 641
VAL A 637
 None
 1.24A 4c9pA-4wrnA:
undetectable		 4c9pA-4wrnA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wv3 ANTHRANILATE-COA
LIGASE

(Stigmatella
aurantiaca) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 TYR A 264
THR A 212
LEU A 206
LEU A 204
GLY A 205
 None
 1.40A 4c9pA-4wv3A:
undetectable		 4c9pA-4wv3A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a3j PUTATIVE
QUINONE-OXIDOREDUCTA
SE HOMOLOG,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		5 THR A  43
THR A 116
LEU A  40
LEU A  38
GLY A  75
 None
 1.34A 4c9pA-5a3jA:
undetectable		 4c9pA-5a3jA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az3 ABC-TYPE
TRANSPORTER,
PERIPLASMIC
COMPONENT

(Corynebacterium
glutamicum) 		PF01497
(Peripla_BP_2) 		5 THR A  69
THR A 108
LEU A 210
GLY A 207
VAL A 201
 None
 1.32A 4c9pA-5az3A:
undetectable		 4c9pA-5az3A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp7 SAM-DEPENDENT
METHYLTRANSFERASE

(Geobacter
sulfurreducens) 		PF13847
(Methyltransf_31) 		5 LEU A  26
LEU A  29
GLY A  30
VAL A  41
VAL A 107
 None
 0.76A 4c9pA-5bp7A:
undetectable		 4c9pA-5bp7A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d8m METAGENOMIC CARBOXYL
ESTERASE MGS0156

(uncultured
organism) 		no annotation 5 THR A 252
THR A 230
LEU A 242
VAL A 198
VAL A 166
 None
 1.27A 4c9pA-5d8mA:
undetectable		 4c9pA-5d8mA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfa BETA-GALACTOSIDASE

(Geobacillus
stearothermophilus) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		5 THR A  48
THR A  10
LEU A 359
LEU A 320
VAL A 406
 None
 1.16A 4c9pA-5dfaA:
undetectable		 4c9pA-5dfaA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmn HOMOCYSTEINE
S-METHYLTRANSFERASE

(Escherichia
coli) 		PF02574
(S-methyl_trans) 		5 THR A 246
LEU A 239
LEU A 250
GLY A 226
VAL A 213
 None
 1.33A 4c9pA-5dmnA:
undetectable		 4c9pA-5dmnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epe SAM-DEPENDENT
METHYLTRANSFERASE

(Thiobacillus
denitrificans) 		PF13847
(Methyltransf_31) 		5 LEU A  25
LEU A  28
GLY A  29
VAL A  40
VAL A 106
 None
 0.74A 4c9pA-5epeA:
undetectable		 4c9pA-5epeA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffp IMMUNITY 23 FAMILY
PROTEIN

(Burkholderia
dolosa) 		PF15593
(Imm42) 		5 LEU A 105
LEU A  29
GLY A  30
VAL A 148
VAL A 151
 None
 1.33A 4c9pA-5ffpA:
undetectable		 4c9pA-5ffpA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gja 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
OXIDASE 2

(Arabidopsis
thaliana) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		5 TRP A  89
LEU A  72
GLY A  76
VAL A  84
VAL A  87
 None
 1.23A 4c9pA-5gjaA:
undetectable		 4c9pA-5gjaA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		5 TRP A 220
LEU A 239
GLY A 238
VAL A 200
VAL A 201
 None
 1.38A 4c9pA-5gjeA:
undetectable		 4c9pA-5gjeA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iw7 RIBOSOME BIOGENESIS
PROTEIN
TSR1,RIBOSOME
BIOGENESIS PROTEIN
TSR1

(Saccharomyces
cerevisiae) 		PF04950
(RIBIOP_C)
PF08142
(AARP2CN) 		5 THR A 663
LEU A 585
LEU A 584
GLY A 583
VAL A 620
 None
 1.30A 4c9pA-5iw7A:
undetectable		 4c9pA-5iw7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE

(Rhodococcus
hoagii) 		PF00150
(Cellulase) 		5 THR A  71
LEU A  66
LEU A 112
VAL A  88
VAL A 126
 None
 1.32A 4c9pA-5j7zA:
undetectable		 4c9pA-5j7zA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxm PRIB

(Streptomyces
sp. RM-5-8) 		PF11991
(Trp_DMAT) 		5 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.82A 4c9pA-5jxmA:
undetectable		 4c9pA-5jxmA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kar ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3B

(Mus musculus) 		PF00149
(Metallophos) 		5 TYR A 151
LEU A 132
GLY A 133
VAL A 108
VAL A 112
 None
 1.33A 4c9pA-5karA:
undetectable		 4c9pA-5karA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE

(Arabidopsis
thaliana) 		PF02458
(Transferase) 		5 LEU A 279
LEU A 366
GLY A 367
VAL A 402
VAL A 414
 None
 1.25A 4c9pA-5kjuA:
undetectable		 4c9pA-5kjuA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lae PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE
OXIDASE,PEROXISOMAL
N(1)-ACETYL-SPERMINE
/SPERMIDINE OXIDASE

(Mus musculus) 		PF01593
(Amino_oxidase) 		5 THR A 222
THR A 279
GLY A  19
VAL A  35
VAL A  10
 None
 1.20A 4c9pA-5laeA:
undetectable		 4c9pA-5laeA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus) 		no annotation 5 THR A  70
THR A  92
LEU A 115
LEU A 100
GLY A 101
 None
 1.40A 4c9pA-5n9mA:
undetectable		 4c9pA-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		5 TRP A1741
TYR A1738
THR A1788
LEU A1815
LEU A1811
 None
 1.39A 4c9pA-5nugA:
undetectable		 4c9pA-5nugA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT B
TUNGSTEN-CONTAINING
FORMYLMETHANOFURAN
DEHYDROGENASE 2
SUBUNIT C

(Methanothermobacter
sp. CaT2;
Methanothermobacter
wolfeii) 		PF00384
(Molybdopterin)
PF01493
(GXGXG) 		5 TYR B 207
THR B 268
LEU C 219
GLY C 221
VAL B 227
 None
 1.34A 4c9pA-5t5iB:
undetectable		 4c9pA-5t5iB:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE

(Homo sapiens;
Pyrococcus
abyssi) 		PF00001
(7tm_1)
PF00534
(Glycos_transf_1) 		5 TRP A 279
THR A 283
LEU A 359
LEU A 360
GLY A 357
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.40A 4c9pA-5u09A:
undetectable		 4c9pA-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE

(Homo sapiens;
Pyrococcus
abyssi) 		PF00001
(7tm_1)
PF00534
(Glycos_transf_1) 		5 TRP A 279
THR A 283
LEU A 359
LEU A 360
VAL A 204
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.40A 4c9pA-5u09A:
undetectable		 4c9pA-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5umx GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE

(Streptomyces
sp. CB03234) 		no annotation 5 LEU A  73
LEU A 116
GLY A 115
VAL A  90
VAL A  92
 None
 1.35A 4c9pA-5umxA:
undetectable		 4c9pA-5umxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vev PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Neisseria
gonorrhoeae) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		5 THR A 294
THR A  37
GLY A   9
VAL A   5
VAL A  30
 None
 1.33A 4c9pA-5vevA:
undetectable		 4c9pA-5vevA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf6 SINGLE CHAIN
VARIABLE FRAGMENT

(Gallus gallus) 		no annotation 5 TYR A 218
THR A 216
LEU A 168
GLY A 167
VAL A  82
 None
 1.29A 4c9pA-5vf6A:
undetectable		 4c9pA-5vf6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA

(Pseudomonas
aeruginosa) 		PF16957
(Mal_decarbox_Al) 		5 THR A 445
LEU A 126
LEU A 121
GLY A 118
VAL A 441
 None
 1.36A 4c9pA-5vj1A:
undetectable		 4c9pA-5vj1A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmk BIFUNCTIONAL PROTEIN
GLMU

(Acinetobacter
baumannii) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3)
PF14602
(Hexapep_2) 		5 TRP A  70
THR A  62
THR A  50
LEU A  33
GLY A  34
 None
 1.37A 4c9pA-5vmkA:
undetectable		 4c9pA-5vmkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vod FAB 9I6 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		5 THR H 192
LEU H 151
GLY H 166
VAL H 225
VAL H 179
 None
 1.39A 4c9pA-5vodH:
undetectable		 4c9pA-5vodH:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vxz GROWTH
ARREST-SPECIFIC
PROTEIN 6

(Homo sapiens) 		PF00054
(Laminin_G_1)
PF02210
(Laminin_G_2) 		5 TYR A 492
THR A 621
LEU A 525
LEU A 535
VAL A 579
 None
 1.35A 4c9pA-5vxzA:
undetectable		 4c9pA-5vxzA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wde KINESIN-LIKE PROTEIN
KIFC3

(Homo sapiens) 		PF00225
(Kinesin) 		5 THR A 739
THR A 726
LEU A 704
GLY A 705
VAL A 718
 None
 1.27A 4c9pA-5wdeA:
undetectable		 4c9pA-5wdeA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xw3 O-ACETYLSERINE LYASE

(Bacillus
anthracis) 		PF00291
(PALP) 		5 THR A 284
THR A 288
LEU A  30
VAL A 200
VAL A 174
 None
 1.22A 4c9pA-5xw3A:
undetectable		 4c9pA-5xw3A:
22.25