SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9N_B_CAMB1420
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bs0 | PROTEIN(8-AMINO-7-OXONANOATE SYNTHASE) (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | THR A 209GLY A 242VAL A 231ASP A 204VAL A 232 | None | 1.34A | 4c9nB-1bs0A:0.0 | 4c9nB-1bs0A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 5 | TRP A 377THR A 65LEU A 404LEU A 398VAL A 287 | None | 1.31A | 4c9nB-1d2kA:0.0 | 4c9nB-1d2kA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fsu | N-ACETYLGALACTOSAMINE-4-SULFATASE (Homo sapiens) |
PF00884(Sulfatase) | 5 | THR A 368THR A 107LEU A 371GLY A 101VAL A 122 | None | 1.27A | 4c9nB-1fsuA:undetectable | 4c9nB-1fsuA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gso | PROTEIN (GLYCINAMIDERIBONUCLEOTIDESYNTHETASE) (Escherichiacoli) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | THR A 296THR A 37GLY A 9VAL A 5VAL A 30 | None | 1.33A | 4c9nB-1gsoA:0.0 | 4c9nB-1gsoA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hxi | PEROXISOME TARGETINGSIGNAL 1 RECEPTORPEX5 (Trypanosomabrucei) |
no annotation | 5 | THR A 392LEU A 360LEU A 357GLY A 356VAL A 375 | None | 1.26A | 4c9nB-1hxiA:undetectable | 4c9nB-1hxiA:14.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7j | PROTEIN YCIO (Escherichiacoli) |
PF01300(Sua5_yciO_yrdC) | 5 | THR A 118THR A 98VAL A 195ASP A 186VAL A 184 | NoneSO4 A 207 ( 4.9A)NoneNoneNone | 1.12A | 4c9nB-1k7jA:0.0 | 4c9nB-1k7jA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n0w | DNA REPAIR PROTEINRAD51 HOMOLOG 1 (Homo sapiens) |
PF08423(Rad51) | 5 | THR A 298LEU A 109LEU A 113GLY A 116VAL A 264 | NoneNone MG A 401 (-4.2A) MG A 401 (-3.8A)None | 1.09A | 4c9nB-1n0wA:undetectable | 4c9nB-1n0wA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | APOCYTOCHROME FCYTOCHROME B6FCOMPLEX SUBUNIT PETLCYTOCHROME B6FCOMPLEX SUBUNIT PETN (Chlamydomonasreinhardtii;Chlamydomonasreinhardtii;Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N)PF05115(PetL)PF03742(PetN) | 5 | TRP N 93LEU L 23LEU L 19GLY L 20VAL A 267 | None | 1.31A | 4c9nB-1q90N:undetectable | 4c9nB-1q90N:8.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 5 | TYR A 183THR A 130LEU A 136VAL A 152VAL A 179 | SAH A1501 (-4.8A)SAH A1501 ( 3.6A)NoneNoneNone | 1.25A | 4c9nB-1s4dA:undetectable | 4c9nB-1s4dA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 398LEU A 401GLY A 402VAL A 369VAL A 366 | None | 1.10A | 4c9nB-1xb7A:0.0 | 4c9nB-1xb7A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y1p | ALDEHYDE REDUCTASEII (Sporidiobolussalmonicolor) |
PF01370(Epimerase) | 5 | THR A 312LEU A 316LEU A 319GLY A 326VAL A 248 | None | 1.28A | 4c9nB-1y1pA:undetectable | 4c9nB-1y1pA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7d | ORNITHINEAMINOTRANSFERASE (Plasmodiumyoelii) |
PF00202(Aminotran_3) | 5 | THR A 385THR A 381LEU A 348GLY A 203VAL A 377 | None | 1.20A | 4c9nB-1z7dA:undetectable | 4c9nB-1z7dA:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7u | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Thermusthermophilus) |
PF00202(Aminotran_3) | 5 | TRP A 394LEU A 417LEU A 420VAL A 350VAL A 359 | None | 1.33A | 4c9nB-2e7uA:undetectable | 4c9nB-2e7uA:23.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | TYR A 96THR A 101LEU A 244GLY A 248VAL A 295 | CAM A 502 (-4.5A)HEM A 501 (-2.9A)HEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-4.6A) | 1.09A | 4c9nB-2m56A:57.7 | 4c9nB-2m56A:44.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 8 | TYR A 96THR A 101THR A 185LEU A 244GLY A 248VAL A 295ASP A 297VAL A 396 | CAM A 502 (-4.5A)HEM A 501 (-2.9A)NoneHEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-4.6A)HEM A 501 (-2.8A)None | 0.58A | 4c9nB-2m56A:57.7 | 4c9nB-2m56A:44.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oga | TRANSAMINASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 5 | THR A 206LEU A 218GLY A 77VAL A 162VAL A 184 | None | 1.26A | 4c9nB-2ogaA:undetectable | 4c9nB-2ogaA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3j | VP4 (Rotavirus A) |
PF00426(VP4_haemagglut) | 5 | THR A 191THR A 176LEU A 103GLY A 95VAL A 167 | None | 1.20A | 4c9nB-2p3jA:undetectable | 4c9nB-2p3jA:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfy | PUTATIVE EXPORTEDPROTEIN (Bordetellapertussis) |
PF03480(DctP) | 5 | THR A 99LEU A 295LEU A 296ASP A 80VAL A 82 | None | 1.24A | 4c9nB-2pfyA:undetectable | 4c9nB-2pfyA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qa1 | POLYKETIDE OXYGENASEPGAE (Streptomycessp. PGA64) |
PF01494(FAD_binding_3) | 5 | LEU A 17LEU A 298GLY A 299VAL A 306VAL A 305 | None | 1.16A | 4c9nB-2qa1A:undetectable | 4c9nB-2qa1A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rq6 | ATP SYNTHASE EPSILONCHAIN (Thermosynechococcuselongatus) |
PF00401(ATP-synt_DE)PF02823(ATP-synt_DE_N) | 5 | THR A 42LEU A 24LEU A 31GLY A 32VAL A 69 | None | 1.18A | 4c9nB-2rq6A:undetectable | 4c9nB-2rq6A:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rq7 | ATP SYNTHASE EPSILONCHAIN (Spinaciaoleracea;Thermosynechococcuselongatus) |
PF00401(ATP-synt_DE)PF02823(ATP-synt_DE_N) | 5 | LEU A 24LEU A 31GLY A 32VAL A 74VAL A 69 | None | 1.28A | 4c9nB-2rq7A:undetectable | 4c9nB-2rq7A:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu0 | PHYTASE (Klebsiellapneumoniae) |
PF00328(His_Phos_2) | 5 | THR A 104GLY A 58VAL A 65ASP A 110VAL A 64 | None | 1.04A | 4c9nB-2wu0A:undetectable | 4c9nB-2wu0A:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yg8 | DNA-3-METHYLADENINEGLYCOSIDASE II,PUTATIVE (Deinococcusradiodurans) |
PF00730(HhH-GPD) | 5 | THR A 197GLY A 183VAL A 41ASP A 39VAL A 45 | NoneNoneGOL A1228 (-4.2A)NoneNone | 1.26A | 4c9nB-2yg8A:undetectable | 4c9nB-2yg8A:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z01 | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Geobacilluskaustophilus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 74LEU A 206GLY A 218VAL A 194VAL A 198 | None | 1.29A | 4c9nB-2z01A:undetectable | 4c9nB-2z01A:25.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwv | PROBABLE RIBOSOMALRNA SMALL SUBUNITMETHYLTRANSFERASE (Thermusthermophilus) |
PF05175(MTS) | 5 | LEU A 220LEU A 223VAL A 258ASP A 239VAL A 237 | NoneNoneNoneSAH A 376 ( 4.2A)None | 1.17A | 4c9nB-2zwvA:undetectable | 4c9nB-2zwvA:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asa | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydiatrachomatis) |
PF00155(Aminotran_1_2) | 5 | TRP A 247THR A 207LEU A 292LEU A 289GLY A 288 | None | 0.82A | 4c9nB-3asaA:undetectable | 4c9nB-3asaA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3d | PUTATIVE MORPHINEDEHYDROGENASE (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 5 | THR A 50LEU A 107LEU A 105GLY A 61VAL A 24 | None | 1.10A | 4c9nB-3b3dA:undetectable | 4c9nB-3b3dA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dla | GLUTAMINE-DEPENDENTNAD(+) SYNTHETASE (Mycobacteriumtuberculosis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 5 | TYR A 7THR A 276LEU A 310LEU A 166VAL A 196 | None | 1.26A | 4c9nB-3dlaA:undetectable | 4c9nB-3dlaA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9t | L-TYROSINEDECARBOXYLASE MFNA (Methanocaldococcusjannaschii) |
PF00282(Pyridoxal_deC) | 5 | LEU A 99LEU A 102GLY A 138ASP A 206VAL A 127 | NoneNoneNonePLP A 500 (-2.6A)None | 1.30A | 4c9nB-3f9tA:undetectable | 4c9nB-3f9tA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fha | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Glutamicibacterprotophormiae) |
PF03644(Glyco_hydro_85) | 5 | TRP A 282LEU A 55LEU A 296GLY A 297VAL A 271 | None | 1.20A | 4c9nB-3fhaA:undetectable | 4c9nB-3fhaA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 274LEU A 191GLY A 226VAL A 240VAL A 217 | None | 1.35A | 4c9nB-3g1uA:undetectable | 4c9nB-3g1uA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jq3 | LOMBRICINE KINASE (Urechis caupo) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | THR A 120LEU A 244LEU A 98GLY A 241VAL A 337 | None | 1.30A | 4c9nB-3jq3A:undetectable | 4c9nB-3jq3A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwt | NUCLEOPROTEIN (Lassamammarenavirus) |
PF00843(Arena_nucleocap)PF17290(Arena_ncap_C) | 5 | THR A 324LEU A 182GLY A 243VAL A 50VAL A 47 | None | 1.34A | 4c9nB-3mwtA:undetectable | 4c9nB-3mwtA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndn | O-SUCCINYLHOMOSERINESULFHYDRYLASE (Mycobacteriumtuberculosis) |
PF01053(Cys_Met_Meta_PP) | 5 | THR A 181THR A 166LEU A 193GLY A 205ASP A 176 | None | 1.13A | 4c9nB-3ndnA:undetectable | 4c9nB-3ndnA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3noq | THIJ/PFPI FAMILYPROTEIN (Pseudomonasfluorescens) |
PF01965(DJ-1_PfpI) | 5 | THR A 120LEU A 128LEU A 131GLY A 108VAL A 74 | None | 1.24A | 4c9nB-3noqA:undetectable | 4c9nB-3noqA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzr | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Vibrio cholerae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 346LEU A 146LEU A 143GLY A 144VAL A 304 | None | 1.20A | 4c9nB-3pzrA:undetectable | 4c9nB-3pzrA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sh5 | LG3 PEPTIDE (Homo sapiens) |
PF00054(Laminin_G_1) | 5 | THR A 40LEU A 73LEU A 68GLY A 67VAL A 160 | None | 1.16A | 4c9nB-3sh5A:undetectable | 4c9nB-3sh5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t4c | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE 1 (Burkholderiaambifaria) |
PF00793(DAHP_synth_1) | 5 | TYR A 49THR A 29THR A 89LEU A 76GLY A 72 | None | 0.92A | 4c9nB-3t4cA:undetectable | 4c9nB-3t4cA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5q | NUCLEOPROTEIN (Mopeia Lassavirusreassortant 29) |
PF00843(Arena_nucleocap) | 5 | THR A 324LEU A 182GLY A 243VAL A 50VAL A 47 | None | 1.35A | 4c9nB-3t5qA:undetectable | 4c9nB-3t5qA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw3 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Burkholderiathailandensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 350LEU A 146LEU A 143GLY A 144VAL A 308 | None | 1.28A | 4c9nB-3uw3A:undetectable | 4c9nB-3uw3A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9a | PUTATIVEUNCHARACTERIZEDPROTEIN (Coprinopsiscinerea) |
no annotation | 5 | TYR A 179LEU A 144GLY A 156VAL A 202VAL A 203 | None | 1.09A | 4c9nB-3w9aA:undetectable | 4c9nB-3w9aA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvr | PGM1 (Streptomycescirratus) |
no annotation | 5 | TYR A 50LEU A 388GLY A 396VAL A 350VAL A 346 | None | 1.33A | 4c9nB-3wvrA:undetectable | 4c9nB-3wvrA:25.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bms | ALCLOHOLDEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE (Ralstonia sp.DSMZ 6428) |
PF13561(adh_short_C2) | 5 | THR A 135THR A 118GLY A 13VAL A 110VAL A 61 | NAP A1250 (-4.1A)NoneNAP A1250 (-3.1A)NAP A1250 (-4.9A)NAP A1250 (-3.7A) | 1.35A | 4c9nB-4bmsA:undetectable | 4c9nB-4bmsA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | THR A 44THR A 12LEU A 80VAL A 5ASP A 6 | None | 1.16A | 4c9nB-4c7vA:undetectable | 4c9nB-4c7vA:21.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 7 | TRP A 89TYR A 98THR A 103LEU A 252LEU A 255GLY A 256VAL A 303 | NoneNoneGOL A1419 (-3.8A)HEM A1418 (-4.0A)GOL A1419 ( 4.9A)HEM A1418 (-3.8A)GOL A1419 (-3.9A) | 1.16A | 4c9nB-4c9mA:70.8 | 4c9nB-4c9mA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 10 | TRP A 89TYR A 98THR A 103THR A 187LEU A 252LEU A 255GLY A 256VAL A 303ASP A 305VAL A 404 | NoneNoneGOL A1419 (-3.8A)NoneHEM A1418 (-4.0A)GOL A1419 ( 4.9A)HEM A1418 (-3.8A)GOL A1419 (-3.9A)HEM A1418 (-2.7A)GOL A1419 (-3.5A) | 0.17A | 4c9nB-4c9mA:70.8 | 4c9nB-4c9mA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | THR A 101LEU A 250GLY A 254VAL A 301VAL A 402 | HEM A 501 ( 4.8A)HEM A 501 (-4.3A)PEG A 502 (-3.8A)PEG A 502 ( 4.5A)None | 0.76A | 4c9nB-4dxyA:55.0 | 4c9nB-4dxyA:61.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gj1 | 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO]IMIDAZOLE-4-CARBOXAMIDE ISOMERASE (Campylobacterjejuni) |
PF00977(His_biosynth) | 5 | THR A 2LEU A 241LEU A 211VAL A 184VAL A 182 | None | 1.27A | 4c9nB-4gj1A:undetectable | 4c9nB-4gj1A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hac | MEVALONATE KINASE (Methanosarcinamazei) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | THR A 291THR A 257LEU A 31LEU A 92GLY A 8 | None | 1.29A | 4c9nB-4hacA:undetectable | 4c9nB-4hacA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j7b | POLO-LIKE KINASE (Danio rerio) |
PF00069(Pkinase) | 5 | THR A 146THR A 229LEU A 168LEU A 165GLY A 166 | None | 1.34A | 4c9nB-4j7bA:undetectable | 4c9nB-4j7bA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k9q | BENZOYLFORMATEDECARBOXYLASE (Polynucleobacternecessarius) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | THR A 441THR A 19LEU A 412GLY A 409VAL A 65 | None | 1.28A | 4c9nB-4k9qA:undetectable | 4c9nB-4k9qA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kdw | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 5 | THR A 56GLY A 32VAL A 83ASP A 43VAL A 45 | NoneNoneNoneGOL A 208 (-4.4A)None | 1.13A | 4c9nB-4kdwA:undetectable | 4c9nB-4kdwA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke4 | HYDROXYCINNAMOYL-COA:SHIKIMATEHYDROXYCINNAMOYLTRANSFERASE (Sorghum bicolor) |
PF02458(Transferase) | 5 | LEU A 295LEU A 381GLY A 382VAL A 417VAL A 429 | None | 1.33A | 4c9nB-4ke4A:undetectable | 4c9nB-4ke4A:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4krg | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE1 (Haemonchuscontortus) |
PF08241(Methyltransf_11) | 5 | LEU A 44LEU A 47VAL A 76ASP A 57VAL A 55 | None | 1.25A | 4c9nB-4krgA:undetectable | 4c9nB-4krgA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le6 | ORGANOPHOSPHORUSHYDROLASE (Pseudomonaspseudoalcaligenes) |
PF00753(Lactamase_B) | 5 | THR A 231THR A 134LEU A 220LEU A 214VAL A 101 | EDO A 403 (-3.2A)NoneEDO A 403 ( 4.8A)NoneNone | 1.18A | 4c9nB-4le6A:undetectable | 4c9nB-4le6A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0k | ADENINEPHOSPHORIBOSYLTRANSFERASE (Rhodothermusmarinus) |
PF00156(Pribosyltran) | 5 | THR A 173LEU A 165GLY A 161VAL A 126ASP A 124 | NoneNoneNoneAMP A 300 (-3.9A)AMP A 300 (-3.0A) | 1.28A | 4c9nB-4m0kA:undetectable | 4c9nB-4m0kA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfi | SN-GLYCEROL-3-PHOSPHATE ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN USPB (Mycobacteriumtuberculosis) |
PF13416(SBP_bac_8) | 5 | THR A 331LEU A 99LEU A 309GLY A 308VAL A 348 | None | 1.01A | 4c9nB-4mfiA:undetectable | 4c9nB-4mfiA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1a | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 5 | THR A1310LEU A1271GLY A1270VAL A1102ASP A1095 | ATP A1402 (-4.7A)NoneNoneNoneNone | 1.28A | 4c9nB-4n1aA:undetectable | 4c9nB-4n1aA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n91 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Anaerococcusprevotii) |
PF03480(DctP) | 5 | THR A 147GLY A 48VAL A 93ASP A 242VAL A 244 | NoneNoneNoneGCU A 401 ( 2.7A)None | 0.87A | 4c9nB-4n91A:undetectable | 4c9nB-4n91A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nh0 | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 5 | THR A1310LEU A1271GLY A1270VAL A1102ASP A1095 | ATP A1404 (-4.4A)NoneNoneNoneNone | 1.30A | 4c9nB-4nh0A:undetectable | 4c9nB-4nh0A:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oh0 | BETA-LACTAMASEOXA-58 (Acinetobacterbaumannii) |
PF00905(Transpeptidase) | 5 | THR A 59LEU A 274GLY A 275VAL A 238VAL A 246 | None | 1.05A | 4c9nB-4oh0A:undetectable | 4c9nB-4oh0A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p49 | ANTIBODY SCFV B8 (Gallus gallus) |
PF07686(V-set) | 5 | TYR A 216THR A 214LEU A 165GLY A 164ASP A 36 | None | 1.35A | 4c9nB-4p49A:undetectable | 4c9nB-4p49A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 56GLY A 32VAL A 83ASP A 43VAL A 45 | NoneNoneNone CA A 510 ( 4.9A)None | 1.14A | 4c9nB-4p99A:undetectable | 4c9nB-4p99A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 160GLY A 136VAL A 187ASP A 147VAL A 149 | NoneNoneNone CA A 507 ( 4.9A)None | 1.11A | 4c9nB-4p99A:undetectable | 4c9nB-4p99A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 264GLY A 240VAL A 291ASP A 251VAL A 253 | NoneNoneNone CA A 520 ( 4.7A)None | 1.12A | 4c9nB-4p99A:undetectable | 4c9nB-4p99A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p99 | MPAFP_RIITETRA-TANDEMER (Marinomonasprimoryensis) |
no annotation | 5 | THR A 368GLY A 344VAL A 395ASP A 355VAL A 357 | None | 1.13A | 4c9nB-4p99A:undetectable | 4c9nB-4p99A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ptz | FMN REDUCTASE SSUE (Escherichiacoli) |
no annotation | 5 | THR C 166LEU C 104LEU C 102GLY C 135ASP C 161 | None | 1.29A | 4c9nB-4ptzC:undetectable | 4c9nB-4ptzC:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbu | ZMAA (Bacillus cereus) |
PF00698(Acyl_transf_1) | 5 | THR A 382LEU A 98GLY A 190VAL A 258VAL A 352 | None | 1.21A | 4c9nB-4qbuA:undetectable | 4c9nB-4qbuA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyr | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | THR A3057LEU A2995LEU A3044GLY A3045VAL A3048 | None | 1.26A | 4c9nB-4qyrA:undetectable | 4c9nB-4qyrA:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r33 | NOSL (Streptomycesactuosus) |
PF06968(BATS) | 5 | TYR A 242LEU A 187GLY A 158ASP A 195VAL A 172 | None | 1.04A | 4c9nB-4r33A:undetectable | 4c9nB-4r33A:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | THR A 708THR A 564LEU A 580LEU A 577GLY A 576 | None | 1.14A | 4c9nB-4rbnA:undetectable | 4c9nB-4rbnA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrn | MALTOSE-BINDINGPERIPLASMICPROTEIN,UROMODULIN (Escherichiacoli;Homo sapiens) |
PF00100(Zona_pellucida)PF13416(SBP_bac_8) | 5 | THR A 589LEU A 601LEU A 602GLY A 641VAL A 637 | None | 1.25A | 4c9nB-4wrnA:undetectable | 4c9nB-4wrnA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 5 | LEU A 17LEU A 298GLY A 299VAL A 306VAL A 305 | None | 1.15A | 4c9nB-4x4jA:undetectable | 4c9nB-4x4jA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5t | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT K (Oryctolaguscuniculus) |
PF10075(CSN8_PSD8_EIF3K) | 5 | LEU K 165LEU K 162GLY K 163ASP K 136VAL K 138 | None | 1.31A | 4c9nB-5a5tK:undetectable | 4c9nB-5a5tK:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az3 | ABC-TYPETRANSPORTER,PERIPLASMICCOMPONENT (Corynebacteriumglutamicum) |
PF01497(Peripla_BP_2) | 5 | THR A 69THR A 108LEU A 210GLY A 207VAL A 201 | None | 1.34A | 4c9nB-5az3A:undetectable | 4c9nB-5az3A:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | LEU A 26LEU A 29GLY A 30ASP A 43VAL A 107 | NoneNoneNoneSAH A 301 ( 4.5A)None | 1.06A | 4c9nB-5bp7A:undetectable | 4c9nB-5bp7A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | LEU A 26LEU A 29GLY A 30VAL A 41VAL A 107 | None | 0.70A | 4c9nB-5bp7A:undetectable | 4c9nB-5bp7A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d8m | METAGENOMIC CARBOXYLESTERASE MGS0156 (unculturedorganism) |
no annotation | 5 | THR A 252THR A 230LEU A 242VAL A 198VAL A 166 | None | 1.29A | 4c9nB-5d8mA:undetectable | 4c9nB-5d8mA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfa | BETA-GALACTOSIDASE (Geobacillusstearothermophilus) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | THR A 48THR A 10LEU A 359LEU A 320VAL A 406 | None | 1.19A | 4c9nB-5dfaA:undetectable | 4c9nB-5dfaA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmn | HOMOCYSTEINES-METHYLTRANSFERASE (Escherichiacoli) |
PF02574(S-methyl_trans) | 5 | THR A 246LEU A 239LEU A 250GLY A 226VAL A 213 | None | 1.29A | 4c9nB-5dmnA:undetectable | 4c9nB-5dmnA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 25LEU A 28GLY A 29ASP A 42VAL A 106 | NoneNoneNoneSAH A 301 ( 4.5A)None | 1.10A | 4c9nB-5epeA:undetectable | 4c9nB-5epeA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 25LEU A 28GLY A 29VAL A 40VAL A 106 | None | 0.68A | 4c9nB-5epeA:undetectable | 4c9nB-5epeA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 28LEU A 32GLY A 29ASP A 42VAL A 40 | NoneNoneNoneSAH A 301 ( 4.5A)None | 1.34A | 4c9nB-5epeA:undetectable | 4c9nB-5epeA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffp | IMMUNITY 23 FAMILYPROTEIN (Burkholderiadolosa) |
PF15593(Imm42) | 5 | LEU A 105LEU A 29GLY A 30VAL A 148VAL A 151 | None | 1.32A | 4c9nB-5ffpA:undetectable | 4c9nB-5ffpA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irb | RTX-ADHESIN (Marinomonasprimoryensis) |
no annotation | 5 | THR A 446GLY A 422VAL A 473ASP A 433VAL A 435 | None | 1.14A | 4c9nB-5irbA:undetectable | 4c9nB-5irbA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw7 | RIBOSOME BIOGENESISPROTEINTSR1,RIBOSOMEBIOGENESIS PROTEINTSR1 (Saccharomycescerevisiae) |
PF04950(RIBIOP_C)PF08142(AARP2CN) | 5 | THR A 663LEU A 585LEU A 584GLY A 583VAL A 620 | None | 1.33A | 4c9nB-5iw7A:undetectable | 4c9nB-5iw7A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j7z | PUTATIVE SECRETEDENDOGLYCOSYLCERAMIDASE (Rhodococcushoagii) |
PF00150(Cellulase) | 5 | THR A 71LEU A 66LEU A 112VAL A 88VAL A 126 | None | 1.31A | 4c9nB-5j7zA:undetectable | 4c9nB-5j7zA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxm | PRIB (Streptomycessp. RM-5-8) |
PF11991(Trp_DMAT) | 5 | THR A 91LEU A 35GLY A 36VAL A 111VAL A 93 | None | 0.80A | 4c9nB-5jxmA:undetectable | 4c9nB-5jxmA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8g | ANTIFREEZE PROTEIN (Marinomonasprimoryensis) |
no annotation | 5 | THR A 56GLY A 32VAL A 84ASP A 43VAL A 45 | NoneNoneNone CA A 615 ( 4.7A)None | 1.15A | 4c9nB-5k8gA:undetectable | 4c9nB-5k8gA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9x | TRYPTOPHAN SYNTHASEALPHA CHAIN (Legionellapneumophila) |
PF00290(Trp_syntA) | 5 | THR A 33LEU A 99LEU A 50GLY A 51ASP A 80 | None | 1.06A | 4c9nB-5k9xA:undetectable | 4c9nB-5k9xA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kar | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3B (Mus musculus) |
PF00149(Metallophos) | 5 | TYR A 151LEU A 132GLY A 133VAL A 108VAL A 112 | None | 1.33A | 4c9nB-5karA:undetectable | 4c9nB-5karA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kju | SHIKIMATEO-HYDROXYCINNAMOYLTRANSFERASE (Arabidopsisthaliana) |
PF02458(Transferase) | 5 | LEU A 279LEU A 366GLY A 367VAL A 402VAL A 414 | None | 1.21A | 4c9nB-5kjuA:undetectable | 4c9nB-5kjuA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lq3 | CMEB (Campylobacterjejuni) |
PF00873(ACR_tran) | 5 | LEU A 932GLY A 931VAL A 449ASP A 410VAL A 481 | None | 1.35A | 4c9nB-5lq3A:undetectable | 4c9nB-5lq3A:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfh | METHIONYL-TRNASYNTHETASE, PUTATIVE (Trypanosomabrucei) |
no annotation | 5 | THR A 710LEU A 606LEU A 610GLY A 611VAL A 723 | None | 1.06A | 4c9nB-5nfhA:undetectable | 4c9nB-5nfhA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT BTUNGSTEN-CONTAININGFORMYLMETHANOFURANDEHYDROGENASE 2SUBUNIT C (Methanothermobactersp. CaT2;Methanothermobacterwolfeii) |
PF00384(Molybdopterin)PF01493(GXGXG) | 5 | TYR B 207THR B 268LEU C 219GLY C 221VAL B 227 | None | 1.29A | 4c9nB-5t5iB:undetectable | 4c9nB-5t5iB:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5umx | GLYOXALASE/BLEOMYCINRESISANCEPROTEIN/DIOXYGENASE (Streptomycessp. CB03234) |
no annotation | 5 | LEU A 73LEU A 116GLY A 115VAL A 90VAL A 92 | None | 1.33A | 4c9nB-5umxA:undetectable | 4c9nB-5umxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vev | PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (Neisseriagonorrhoeae) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | THR A 294THR A 37GLY A 9VAL A 5VAL A 30 | None | 1.32A | 4c9nB-5vevA:undetectable | 4c9nB-5vevA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxz | GROWTHARREST-SPECIFICPROTEIN 6 (Homo sapiens) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 5 | TYR A 492THR A 621LEU A 525LEU A 535VAL A 579 | None | 1.31A | 4c9nB-5vxzA:undetectable | 4c9nB-5vxzA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cet | GATOR COMPLEXPROTEIN NPRL2 (Homo sapiens) |
no annotation | 5 | TYR N 43THR N 24LEU N 50VAL N 88ASP N 38 | None | 1.32A | 4c9nB-6cetN:undetectable | 4c9nB-6cetN:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fm7 | BETA-LACTAMASE (Aeromonasenteropelogenes) |
no annotation | 5 | TYR A 74THR A 175LEU A 171LEU A 164GLY A 165 | None | 1.29A | 4c9nB-6fm7A:undetectable | 4c9nB-6fm7A:undetectable |