SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9N_A_CAMA1419

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a80 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE A

(Corynebacterium
sp.) 		PF00248
(Aldo_ket_red) 		4 THR A  46
LEU A  99
LEU A  97
GLY A  57
 None
 0.78A 4c9nA-1a80A:
0.0		 4c9nA-1a80A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a80 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE A

(Corynebacterium
sp.) 		PF00248
(Aldo_ket_red) 		4 THR A  46
LEU A  99
LEU A  97
VAL A  33
 None
 0.88A 4c9nA-1a80A:
0.0		 4c9nA-1a80A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3x PENTOSYLTRANSFERASE

(Cellulomonas
sp.) 		PF01048
(PNP_UDP_1) 		4 THR A 121
LEU A 100
GLY A 101
THR A  64
 None
 0.80A 4c9nA-1c3xA:
undetectable		 4c9nA-1c3xA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1col COLICIN A

(Escherichia
coli) 		PF01024
(Colicin) 		5 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.25A 4c9nA-1colA:
0.1		 4c9nA-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1djp GLUTAMINASE-ASPARAGI
NASE

(Pseudomonas sp.
7A) 		PF00710
(Asparaginase) 		4 LEU A1075
LEU A1078
GLY A1079
VAL A1157
 None
 0.79A 4c9nA-1djpA:
0.0		 4c9nA-1djpA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exb KV BETA2 PROTEIN

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		4 THR A  86
LEU A 149
LEU A 147
GLY A 100
 None
 0.77A 4c9nA-1exbA:
0.0		 4c9nA-1exbA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcu HYALURONOGLUCOSAMINI
DASE

(Apis mellifera) 		PF01630
(Glyco_hydro_56) 		4 LEU A 320
LEU A 324
GLY A 325
VAL A  13
 None
 0.87A 4c9nA-1fcuA:
0.0		 4c9nA-1fcuA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m7s CATALASE

(Pseudomonas
syringae) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 THR A 199
LEU A 476
LEU A 479
GLY A 487
 None
 0.85A 4c9nA-1m7sA:
undetectable		 4c9nA-1m7sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mg5 ALCOHOL
DEHYDROGENASE

(Drosophila
melanogaster) 		PF00106
(adh_short) 		4 LEU A  20
LEU A  15
GLY A  14
VAL A  58
 None
 0.83A 4c9nA-1mg5A:
0.0		 4c9nA-1mg5A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhz METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		4 THR D 234
LEU D  89
LEU D  86
GLY D  85
 None
 0.62A 4c9nA-1mhzD:
0.0		 4c9nA-1mhzD:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mzr 2,5-DIKETO-D-GLUCONA
TE REDUCTASE A

(Escherichia
coli) 		PF00248
(Aldo_ket_red) 		4 THR A  48
LEU A  99
LEU A  97
GLY A  59
 None
 0.81A 4c9nA-1mzrA:
undetectable		 4c9nA-1mzrA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n0w DNA REPAIR PROTEIN
RAD51 HOMOLOG 1

(Homo sapiens) 		PF08423
(Rad51) 		5 THR A 298
LEU A 109
LEU A 113
GLY A 116
VAL A 264
 None
None
MG  A 401 (-4.2A)
MG  A 401 (-3.8A)
None
 1.08A 4c9nA-1n0wA:
undetectable		 4c9nA-1n0wA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1of3 BETA-MANNOSIDASE

(Thermotoga
maritima) 		PF09212
(CBM27) 		4 LEU A  94
LEU A 156
GLY A 153
VAL A  52
 None
 0.85A 4c9nA-1of3A:
undetectable		 4c9nA-1of3A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oro OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Escherichia
coli) 		PF00156
(Pribosyltran) 		4 LEU A  46
LEU A  49
GLY A  50
VAL A 123
 None
 0.86A 4c9nA-1oroA:
undetectable		 4c9nA-1oroA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pie GALACTOKINASE

(Lactococcus
lactis) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg) 		4 LEU A 163
LEU A 166
GLY A 167
THR A 170
 None
 0.85A 4c9nA-1pieA:
undetectable		 4c9nA-1pieA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi9 PROTEIN (VANADIUM
BROMOPEROXIDASE)

(Ascophyllum
nodosum) 		no annotation 4 LEU A 435
GLY A 439
THR A 464
VAL A 200
 None
 0.84A 4c9nA-1qi9A:
undetectable		 4c9nA-1qi9A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwk ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1

(Caenorhabditis
elegans) 		PF00248
(Aldo_ket_red) 		4 THR A  48
LEU A 105
LEU A 103
GLY A  59
 None
 0.87A 4c9nA-1qwkA:
undetectable		 4c9nA-1qwkA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlk HYPOTHETICAL PROTEIN
TA0108

(Thermoplasma
acidophilum) 		PF01981
(PTH2) 		4 THR A 111
LEU A  99
GLY A  98
VAL A  58
 None
 0.87A 4c9nA-1rlkA:
undetectable		 4c9nA-1rlkA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES

(Salmonella
enterica) 		PF02613
(Nitrate_red_del) 		5 TRP A  46
THR A 185
LEU A  20
LEU A  17
GLY A  18
 None
 1.48A 4c9nA-1s9uA:
undetectable		 4c9nA-1s9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szp DNA REPAIR PROTEIN
RAD51

(Saccharomyces
cerevisiae) 		PF08423
(Rad51)
PF14520
(HHH_5) 		5 THR A 356
LEU A 167
LEU A 171
GLY A 174
VAL A 322
 None
 1.05A 4c9nA-1szpA:
undetectable		 4c9nA-1szpA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5c CENTROMERIC PROTEIN
E

(Homo sapiens) 		PF00225
(Kinesin) 		4 THR A 205
LEU A 143
LEU A 142
GLY A 185
 None
 0.73A 4c9nA-1t5cA:
undetectable		 4c9nA-1t5cA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t92 GENERAL SECRETION
PATHWAY PROTEIN G

(Klebsiella
pneumoniae) 		PF08334
(T2SSG) 		4 LEU A  67
LEU A  64
GLY A  63
VAL A 109
 None
 0.79A 4c9nA-1t92A:
undetectable		 4c9nA-1t92A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00121
(TIM) 		5 THR A  52
LEU A  21
LEU A  22
GLY A  17
THR A  45
 None
 1.48A 4c9nA-1tcdA:
undetectable		 4c9nA-1tcdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjr BX1

(Zea mays) 		PF00290
(Trp_syntA) 		4 THR A 118
LEU A 183
LEU A 135
GLY A 136
 None
 0.84A 4c9nA-1tjrA:
undetectable		 4c9nA-1tjrA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txg GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Archaeoglobus
fulgidus) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 TRP A  29
THR A  31
LEU A  77
GLY A  83
 None
 0.85A 4c9nA-1txgA:
undetectable		 4c9nA-1txgA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzb GLUCOSE-6-PHOSPHATE
ISOMERASE,
CONJECTURAL

(Pyrobaculum
aerophilum) 		PF10432
(bact-PGI_C) 		4 THR A 125
LEU A 118
GLY A  90
VAL A 128
 None
 0.77A 4c9nA-1tzbA:
undetectable		 4c9nA-1tzbA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1udx THE GTP-BINDING
PROTEIN OBG

(Thermus
thermophilus) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1)
PF09269
(DUF1967) 		4 LEU A 315
LEU A 312
GLY A 311
VAL A 279
 None
 0.78A 4c9nA-1udxA:
undetectable		 4c9nA-1udxA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbj PROSTAGLANDIN F
SYNTHASE

(Trypanosoma
brucei) 		PF00248
(Aldo_ket_red) 		4 THR A  48
LEU A 101
LEU A  99
GLY A  59
 None
 0.72A 4c9nA-1vbjA:
undetectable		 4c9nA-1vbjA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vmi PUTATIVE PHOSPHATE
ACETYLTRANSFERASE

(Escherichia
coli) 		PF01515
(PTA_PTB) 		4 LEU A 140
LEU A 296
GLY A 295
VAL A 169
 None
 0.73A 4c9nA-1vmiA:
undetectable		 4c9nA-1vmiA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp5 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Thermotoga
maritima) 		PF00248
(Aldo_ket_red) 		4 THR A  46
LEU A 103
LEU A 101
GLY A  57
 None
 0.80A 4c9nA-1vp5A:
undetectable		 4c9nA-1vp5A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp5 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE

(Thermotoga
maritima) 		PF00248
(Aldo_ket_red) 		4 THR A  46
LEU A 103
LEU A 101
VAL A  33
 None
 0.86A 4c9nA-1vp5A:
undetectable		 4c9nA-1vp5A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xb7 STEROID HORMONE
RECEPTOR ERR1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 LEU A 398
LEU A 401
GLY A 402
VAL A 369
 None
 0.80A 4c9nA-1xb7A:
undetectable		 4c9nA-1xb7A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xnj BIFUNCTIONAL
3'-PHOSPHOADENOSINE
5'-PHOSPHOSULFATE
SYNTHETASE 1

(Homo sapiens) 		no annotation 4 TYR B 497
LEU B 454
GLY B 455
VAL B 262
 None
 0.86A 4c9nA-1xnjB:
undetectable		 4c9nA-1xnjB:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zgd CHALCONE REDUCTASE

(Medicago sativa) 		PF00248
(Aldo_ket_red) 		4 THR A  54
LEU A 111
LEU A 109
GLY A  65
 None
 0.86A 4c9nA-1zgdA:
undetectable		 4c9nA-1zgdA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy2 TRANSCRIPTIONAL
REGULATOR NTRC1

(Aquifex
aeolicus) 		PF00072
(Response_reg) 		4 THR A  86
LEU A  63
LEU A  60
GLY A  59
 None
None
None
PHD  A  51 ( 3.9A)
 0.86A 4c9nA-1zy2A:
undetectable		 4c9nA-1zy2A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b92 INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 TYR A 128
LEU A  46
LEU A 101
GLY A 102
 TYR  A 128 ( 1.3A)
LEU  A  46 ( 0.5A)
LEU  A 101 ( 0.6A)
GLY  A 102 ( 0.0A)
 0.82A 4c9nA-2b92A:
undetectable		 4c9nA-2b92A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bgs ALDOSE REDUCTASE

(Hordeum vulgare) 		PF00248
(Aldo_ket_red) 		4 THR A  56
LEU A 112
LEU A 110
GLY A  67
 None
 0.80A 4c9nA-2bgsA:
undetectable		 4c9nA-2bgsA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvz 3-HYDROXYISOBUTYRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 THR A 210
LEU A 186
LEU A 183
GLY A 182
 None
 0.85A 4c9nA-2cvzA:
undetectable		 4c9nA-2cvzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ego GENERAL RECEPTOR FOR
PHOSPHOINOSITIDES
1-ASSOCIATED
SCAFFOLD PROTEIN

(Rattus
norvegicus) 		PF00595
(PDZ) 		5 THR A 185
LEU A 101
GLY A 147
THR A 149
VAL A 134
 None
 1.35A 4c9nA-2egoA:
undetectable		 4c9nA-2egoA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcu PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 3

(Arabidopsis
thaliana) 		PF00753
(Lactamase_B) 		4 THR A 129
LEU A 156
GLY A 152
THR A  71
 None
EDO  A2009 ( 4.0A)
None
None
 0.85A 4c9nA-2gcuA:
undetectable		 4c9nA-2gcuA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjm LACTOPEROXIDASE

(Bubalus bubalis) 		PF03098
(An_peroxidase) 		4 THR A 248
LEU A  84
LEU A 384
GLY A 383
 None
 0.61A 4c9nA-2gjmA:
undetectable		 4c9nA-2gjmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kjz ATC0852

(Agrobacterium
fabrum) 		PF00903
(Glyoxalase) 		4 LEU A   9
LEU A  49
GLY A  48
VAL A  27
 None
 0.83A 4c9nA-2kjzA:
undetectable		 4c9nA-2kjzA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kzc UNCHARACTERIZED
PROTEIN

(Jannaschia sp.
CCS1) 		PF07345
(DUF1476) 		4 TRP A  17
LEU A  54
LEU A  57
GLY A  59
 None
 0.69A 4c9nA-2kzcA:
undetectable		 4c9nA-2kzcA:
12.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 THR A 181
LEU A 244
GLY A 248
THR A 252
VAL A 396
 None
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-3.4A)
None
 1.35A 4c9nA-2m56A:
58.0		 4c9nA-2m56A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		5 TYR A  96
LEU A 244
GLY A 248
THR A 252
VAL A 396
 CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-3.4A)
None
 1.30A 4c9nA-2m56A:
58.0		 4c9nA-2m56A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		6 TYR A  96
THR A 185
LEU A 244
GLY A 248
THR A 252
VAL A 295
 CAM  A 502 (-4.5A)
None
HEM  A 501 (-4.5A)
HEM  A 501 (-3.9A)
HEM  A 501 (-3.4A)
HEM  A 501 (-4.6A)
 0.38A 4c9nA-2m56A:
58.0		 4c9nA-2m56A:
44.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m86 E3 UBIQUITIN-PROTEIN
LIGASE MDM2

(Homo sapiens) 		PF02201
(SWIB) 		4 LEU B 119
LEU B 122
GLY B 123
VAL B 140
 None
 0.88A 4c9nA-2m86B:
undetectable		 4c9nA-2m86B:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nm1 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 TYR A1213
LEU A1224
LEU A1237
GLY A1236
 None
 0.88A 4c9nA-2nm1A:
undetectable		 4c9nA-2nm1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2of5 LEUCINE-RICH REPEAT
AND DEATH
DOMAIN-CONTAINING
PROTEIN

(Homo sapiens) 		PF00531
(Death) 		4 TRP H 839
LEU H 787
LEU H 779
GLY H 780
 None
 0.87A 4c9nA-2of5H:
undetectable		 4c9nA-2of5H:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa1 POLYKETIDE OXYGENASE
PGAE

(Streptomyces
sp. PGA64) 		PF01494
(FAD_binding_3) 		4 LEU A  17
LEU A 298
GLY A 299
VAL A 306
 None
 0.86A 4c9nA-2qa1A:
undetectable		 4c9nA-2qa1A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rsp RSV PROTEASE

(Rous sarcoma
virus) 		PF00077
(RVP) 		4 LEU A  95
LEU A  82
GLY A  83
VAL A  13
 None
 0.85A 4c9nA-2rspA:
undetectable		 4c9nA-2rspA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2toh TYROSINE
3-MONOOXYGENASE

(Rattus
norvegicus) 		PF00351
(Biopterin_H) 		4 LEU A 357
LEU A 354
GLY A 353
VAL A 308
 None
 0.87A 4c9nA-2tohA:
undetectable		 4c9nA-2tohA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6b L-LACTATE
DEHYDROGENASE

(Deinococcus
radiodurans) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 THR A  97
LEU A 254
GLY A 251
THR A  35
 None
 0.88A 4c9nA-2v6bA:
undetectable		 4c9nA-2v6bA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3p BENZOYL-COA-DIHYDROD
IOL LYASE

(Paraburkholderia
xenovorans) 		PF00378
(ECH_1) 		4 LEU A  82
LEU A  34
GLY A  35
VAL A  59
 None
None
None
BME  A 602 (-4.6A)
 0.78A 4c9nA-2w3pA:
undetectable		 4c9nA-2w3pA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9m POLYMERASE X

(Deinococcus
radiodurans) 		PF14520
(HHH_5)
PF14716
(HHH_8) 		4 LEU A  99
LEU A  96
GLY A  95
VAL A 519
 None
 0.77A 4c9nA-2w9mA:
undetectable		 4c9nA-2w9mA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2waa XYLAN ESTERASE,
PUTATIVE, AXE2C

(Cellvibrio
japonicus) 		PF13472
(Lipase_GDSL_2) 		5 TYR A 252
THR A 271
LEU A 202
GLY A 139
THR A 143
 None
 1.43A 4c9nA-2waaA:
undetectable		 4c9nA-2waaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbe BIPOLAR KINESIN
KRP-130

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 THR C 221
LEU C 158
LEU C 157
GLY C 201
 None
 0.72A 4c9nA-2wbeC:
undetectable		 4c9nA-2wbeC:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjs LAMININ SUBUNIT
ALPHA-2

(Mus musculus) 		PF00054
(Laminin_G_1) 		4 THR A2552
LEU A2591
LEU A2586
VAL A2680
 None
 0.85A 4c9nA-2wjsA:
undetectable		 4c9nA-2wjsA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtk SERINE/THREONINE-PRO
TEIN KINASE 11

(Homo sapiens) 		PF00069
(Pkinase) 		5 THR C 249
LEU C 290
LEU C 286
GLY C 242
THR C 244
 None
 1.44A 4c9nA-2wtkC:
undetectable		 4c9nA-2wtkC:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzm ALDO-KETO REDUCTASE

(Mycolicibacterium
smegmatis) 		PF00248
(Aldo_ket_red) 		4 THR A  54
LEU A 107
LEU A 105
GLY A  65
 None
 0.84A 4c9nA-2wzmA:
undetectable		 4c9nA-2wzmA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzm ALDO-KETO REDUCTASE

(Mycolicibacterium
smegmatis) 		PF00248
(Aldo_ket_red) 		4 THR A  54
LEU A 107
LEU A 105
VAL A  41
 None
 0.76A 4c9nA-2wzmA:
undetectable		 4c9nA-2wzmA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x77 ADP-RIBOSYLATION
FACTOR

(Leishmania
major) 		PF00025
(Arf) 		4 TYR A  93
LEU A  28
LEU A  71
GLY A  72
 None
 0.81A 4c9nA-2x77A:
undetectable		 4c9nA-2x77A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkr PUTATIVE CYTOCHROME
P450 142

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 LEU A 226
GLY A 230
THR A 234
VAL A 277
 HEM  A1400 (-4.4A)
PG4  A1399 ( 3.2A)
HEM  A1400 (-3.7A)
HEM  A1400 (-4.5A)
 0.87A 4c9nA-2xkrA:
44.2		 4c9nA-2xkrA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzd DARPIN-3.4

(synthetic
construct) 		PF12796
(Ank_2) 		4 THR G  22
LEU G  67
LEU G  66
THR G  49
 None
 0.78A 4c9nA-2xzdG:
undetectable		 4c9nA-2xzdG:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yw4 4-HYDROXY-2-OXOGLUTA
RATE
ALDOLASE/2-DEYDRO-3-
DEOXYPHOSPHOGLUCONAT
E ALDOLASE

(Thermus
thermophilus) 		PF01081
(Aldolase) 		4 LEU A  55
LEU A  52
GLY A  51
THR A  48
 None
 0.80A 4c9nA-2yw4A:
undetectable		 4c9nA-2yw4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a21 PUTATIVE SECRETED
ALPHA-GALACTOSIDASE

(Streptomyces
avermitilis) 		PF00652
(Ricin_B_lectin)
PF16499
(Melibiase_2) 		4 THR A 271
LEU A 456
GLY A 455
VAL A 477
 GOL  A 914 (-3.9A)
None
None
None
 0.69A 4c9nA-3a21A:
undetectable		 4c9nA-3a21A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al8 SEMAPHORIN-6A

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI) 		4 THR A 314
LEU A 448
LEU A 440
GLY A 441
 None
 0.84A 4c9nA-3al8A:
undetectable		 4c9nA-3al8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asa LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Chlamydia
trachomatis) 		PF00155
(Aminotran_1_2) 		4 TRP A 247
LEU A 292
LEU A 289
GLY A 288
 None
 0.47A 4c9nA-3asaA:
undetectable		 4c9nA-3asaA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b3d PUTATIVE MORPHINE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 THR A  50
LEU A 107
LEU A 105
GLY A  61
 None
 0.87A 4c9nA-3b3dA:
undetectable		 4c9nA-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3f YVGN PROTEIN

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 THR A  50
LEU A 103
LEU A 101
GLY A  61
 None
 0.87A 4c9nA-3d3fA:
undetectable		 4c9nA-3d3fA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dla GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		5 TYR A   7
THR A 276
LEU A 310
LEU A 166
VAL A 196
 None
 1.27A 4c9nA-3dlaA:
undetectable		 4c9nA-3dlaA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4b ALGK

(Pseudomonas
fluorescens) 		no annotation 4 TYR A  34
THR A 175
LEU A 145
GLY A 144
 None
 0.88A 4c9nA-3e4bA:
undetectable		 4c9nA-3e4bA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Glutamicibacter
protophormiae) 		PF03644
(Glyco_hydro_85) 		5 TRP A 282
LEU A  55
LEU A 296
GLY A 297
VAL A 271
 None
 1.23A 4c9nA-3fhaA:
undetectable		 4c9nA-3fhaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fqd 5'-3'
EXORIBONUCLEASE 2

(Schizosaccharomyces
pombe) 		PF03159
(XRN_N) 		4 LEU A 238
LEU A 241
GLY A 242
THR A 245
 None
 0.73A 4c9nA-3fqdA:
undetectable		 4c9nA-3fqdA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd8 AQUAPORIN-4

(Homo sapiens) 		PF00230
(MIP) 		4 THR A 137
LEU A 145
GLY A 146
THR A  56
 None
None
GOL  A   1 ( 3.4A)
GOL  A   6 (-4.2A)
 0.80A 4c9nA-3gd8A:
undetectable		 4c9nA-3gd8A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ

(Carboxydothermus
hydrogenoformans) 		PF14450
(FtsA) 		4 LEU A 171
GLY A 167
THR A 148
VAL A 229
 None
 0.87A 4c9nA-3h1qA:
undetectable		 4c9nA-3h1qA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdg UNCHARACTERIZED
PROTEIN

(Wolinella
succinogenes) 		PF00072
(Response_reg) 		4 LEU A  68
GLY A  67
THR A  58
VAL A  83
 None
 0.74A 4c9nA-3hdgA:
undetectable		 4c9nA-3hdgA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 THR B 146
LEU B 207
GLY B 204
VAL B 457
 None
 0.78A 4c9nA-3hhsB:
undetectable		 4c9nA-3hhsB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hul HOMOSERINE KINASE

(Listeria
monocytogenes) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A  29
LEU A  97
GLY A  94
THR A  59
 None
 0.81A 4c9nA-3hulA:
undetectable		 4c9nA-3hulA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4k MUCONATE LACTONIZING
ENZYME

(Corynebacterium
glutamicum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 TYR A 340
LEU A 336
GLY A 332
THR A 303
VAL A  54
 TYR  A 340 ( 1.3A)
LEU  A 336 ( 0.6A)
GLY  A 332 ( 0.0A)
THR  A 303 (-0.8A)
VAL  A  54 ( 0.6A)
 1.27A 4c9nA-3i4kA:
undetectable		 4c9nA-3i4kA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikm DNA POLYMERASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 LEU A1025
LEU A 304
GLY A 303
VAL A 361
 None
 0.83A 4c9nA-3ikmA:
undetectable		 4c9nA-3ikmA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9d OUTER CAPSID PROTEIN
VP2

(Bluetongue
virus) 		PF00898
(Orbi_VP2) 		4 TRP A 860
LEU A 942
LEU A   4
GLY A   5
 None
 0.77A 4c9nA-3j9dA:
undetectable		 4c9nA-3j9dA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfo NUCLEOPORIN NUP133

(Saccharomyces
cerevisiae) 		no annotation 4 TYR A1094
LEU A1037
LEU A1040
VAL A 983
 None
 0.80A 4c9nA-3kfoA:
undetectable		 4c9nA-3kfoA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktd PREPHENATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF02153
(PDH) 		4 THR A  60
LEU A  83
LEU A  13
GLY A  14
 None
 0.88A 4c9nA-3ktdA:
undetectable		 4c9nA-3ktdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx6 FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Babesia bovis) 		PF00274
(Glycolytic) 		4 THR A 168
LEU A 127
LEU A 124
GLY A 123
 None
 0.70A 4c9nA-3kx6A:
undetectable		 4c9nA-3kx6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4k DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		4 THR A 561
LEU A 605
GLY A 606
VAL A 613
 None
 0.85A 4c9nA-3l4kA:
undetectable		 4c9nA-3l4kA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lda DNA REPAIR PROTEIN
RAD51

(Saccharomyces
cerevisiae) 		PF08423
(Rad51)
PF14520
(HHH_5) 		5 THR A 356
LEU A 167
LEU A 171
GLY A 174
VAL A 322
 None
 1.08A 4c9nA-3ldaA:
undetectable		 4c9nA-3ldaA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln3 DIHYDRODIOL
DEHYDROGENASE

(Mus musculus) 		PF00248
(Aldo_ket_red) 		4 THR A  51
LEU A 108
LEU A 106
GLY A  62
 None
None
MLY  A 105 ( 4.3A)
MLY  A 105 ( 4.1A)
 0.79A 4c9nA-3ln3A:
undetectable		 4c9nA-3ln3A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpo PREDICTED HYDROLASE
OF THE HAD
SUPERFAMILY

(Lactobacillus
brevis) 		PF08282
(Hydrolase_3) 		4 THR A 216
LEU A 200
GLY A 198
THR A 225
 None
 0.87A 4c9nA-3mpoA:
undetectable		 4c9nA-3mpoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nep MALATE DEHYDROGENASE

(Salinibacter
ruber) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 THR X  97
LEU X 167
GLY X 251
THR X  35
 None
 0.77A 4c9nA-3nepX:
undetectable		 4c9nA-3nepX:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o80 HEXOKINASE

(Kluyveromyces
lactis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 TYR A 284
LEU A  33
LEU A  30
GLY A  29
 None
 0.73A 4c9nA-3o80A:
2.3		 4c9nA-3o80A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op0 SIGNAL TRANSDUCTION
PROTEIN CBL-C

(Homo sapiens) 		PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3) 		4 THR A 223
LEU A 319
LEU A 322
GLY A 323
 None
 0.87A 4c9nA-3op0A:
undetectable		 4c9nA-3op0A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		5 TRP A 383
LEU A 360
LEU A 349
GLY A 348
THR A 323
 None
 1.35A 4c9nA-3p11A:
undetectable		 4c9nA-3p11A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxg NEGATIVE REGULATOR
OF GENETIC
COMPETENCE CLPC/MECB

(Bacillus
subtilis) 		PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N) 		4 LEU A  50
LEU A  55
GLY A  56
VAL A  64
 None
 0.86A 4c9nA-3pxgA:
undetectable		 4c9nA-3pxgA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxi NEGATIVE REGULATOR
OF GENETIC
COMPETENCE CLPC/MECB

(Bacillus
subtilis) 		PF00004
(AAA)
PF02151
(UVR)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 LEU A  50
LEU A  55
GLY A  56
VAL A  64
 None
 0.86A 4c9nA-3pxiA:
undetectable		 4c9nA-3pxiA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz2 GERANYLGERANYL
TRANSFERASE TYPE-2
SUBUNIT BETA

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		4 THR B 198
LEU B 215
GLY B 216
VAL B 330
 None
 0.82A 4c9nA-3pz2B:
undetectable		 4c9nA-3pz2B:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzr ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Vibrio cholerae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		5 THR A 346
LEU A 146
LEU A 143
GLY A 144
VAL A 304
 None
 1.19A 4c9nA-3pzrA:
undetectable		 4c9nA-3pzrA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8n 4-AMINOBUTYRATE
TRANSAMINASE

(Mycolicibacterium
smegmatis) 		PF00202
(Aminotran_3) 		4 THR A 355
LEU A 441
LEU A 438
GLY A 437
 None
 0.86A 4c9nA-3q8nA:
undetectable		 4c9nA-3q8nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r79 UNCHARACTERIZED
PROTEIN

(Agrobacterium
fabrum) 		PF01168
(Ala_racemase_N) 		4 THR A 144
LEU A 191
LEU A 162
THR A 130
 None
 0.85A 4c9nA-3r79A:
undetectable		 4c9nA-3r79A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sh5 LG3 PEPTIDE

(Homo sapiens) 		PF00054
(Laminin_G_1) 		5 THR A  40
LEU A  73
LEU A  68
GLY A  67
VAL A 160
 None
 1.17A 4c9nA-3sh5A:
undetectable		 4c9nA-3sh5A:
22.44