SIMILAR PATTERNS OF AMINO ACIDS FOR 4C9K_B_CAMB424_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b1c | PROTEIN(NADPH-CYTOCHROMEP450 REDUCTASE) (Homo sapiens) |
PF00258(Flavodoxin_1) | 5 | TRP A 95THR A 99LEU A 132LEU A 135GLY A 136 | None | 1.42A | 4c9kB-1b1cA:undetectable | 4c9kB-1b1cA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c2o | ACETYLCHOLINESTERASE (Electrophoruselectricus) |
PF00135(COesterase) | 5 | TRP A 182GLY A 191THR A 103VAL A 147VAL A 101 | None | 1.34A | 4c9kB-1c2oA:0.0 | 4c9kB-1c2oA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dt2 | EXFOLIATIVE TOXIN B (Staphylococcusaureus) |
PF13365(Trypsin_2) | 5 | LEU A 152LEU A 153GLY A 154THR A 51VAL A 53 | None | 1.45A | 4c9kB-1dt2A:undetectable | 4c9kB-1dt2A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz4 | NAD-DEPENDENT MALICENZYME (Homo sapiens) |
PF00390(malic)PF03949(Malic_M) | 5 | THR A 388LEU A 292LEU A 291GLY A 290VAL A 415 | None | 1.40A | 4c9kB-1gz4A:0.0 | 4c9kB-1gz4A:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m1l | SUPPRESSOR OF FUSED (Homo sapiens) |
PF05076(SUFU) | 5 | LEU A 98GLY A 33THR A 190VAL A 188VAL A 195 | None | 1.42A | 4c9kB-1m1lA:undetectable | 4c9kB-1m1lA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n0w | DNA REPAIR PROTEINRAD51 HOMOLOG 1 (Homo sapiens) |
PF08423(Rad51) | 5 | THR A 123LEU A 109LEU A 113GLY A 116VAL A 264 | NoneNone MG A 401 (-4.2A) MG A 401 (-3.8A)None | 1.49A | 4c9kB-1n0wA:undetectable | 4c9kB-1n0wA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n0w | DNA REPAIR PROTEINRAD51 HOMOLOG 1 (Homo sapiens) |
PF08423(Rad51) | 5 | THR A 298LEU A 109LEU A 113GLY A 116VAL A 264 | NoneNone MG A 401 (-4.2A) MG A 401 (-3.8A)None | 1.07A | 4c9kB-1n0wA:undetectable | 4c9kB-1n0wA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s9u | PUTATIVE COMPONENTOF ANAEROBICDEHYDROGENASES (Salmonellaenterica) |
PF02613(Nitrate_red_del) | 5 | TRP A 46THR A 185LEU A 20LEU A 17GLY A 18 | None | 1.45A | 4c9kB-1s9uA:0.0 | 4c9kB-1s9uA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szp | DNA REPAIR PROTEINRAD51 (Saccharomycescerevisiae) |
PF08423(Rad51)PF14520(HHH_5) | 5 | THR A 356LEU A 167LEU A 171GLY A 174VAL A 322 | None | 1.07A | 4c9kB-1szpA:undetectable | 4c9kB-1szpA:24.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tcd | TRIOSEPHOSPHATEISOMERASE (Trypanosomacruzi) |
PF00121(TIM) | 5 | THR A 52LEU A 21LEU A 22GLY A 17THR A 45 | None | 1.47A | 4c9kB-1tcdA:0.0 | 4c9kB-1tcdA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1udx | THE GTP-BINDINGPROTEIN OBG (Thermusthermophilus) |
PF01018(GTP1_OBG)PF01926(MMR_HSR1)PF09269(DUF1967) | 5 | THR A 208LEU A 162GLY A 161THR A 236VAL A 323 | None | 1.46A | 4c9kB-1udxA:undetectable | 4c9kB-1udxA:25.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umg | 385AA LONG CONSERVEDHYPOTHETICAL PROTEIN (Sulfurisphaeratokodaii) |
PF01950(FBPase_3) | 5 | THR A 49LEU A 292LEU A 293GLY A 294VAL A 8 | None | 1.22A | 4c9kB-1umgA:undetectable | 4c9kB-1umgA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6c | ALKALINE SERINEPROTEASE (Pseudoalteromonassp. AS-11) |
PF00082(Peptidase_S8)PF02225(PA) | 5 | LEU A 257LEU A 278THR A 340VAL A 231VAL A 336 | None | 1.48A | 4c9kB-1v6cA:undetectable | 4c9kB-1v6cA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vko | INOSITOL-3-PHOSPHATESYNTHASE (Caenorhabditiselegans) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 5 | THR A 292LEU A 300LEU A 297GLY A 296VAL A 267 | None | 1.41A | 4c9kB-1vkoA:undetectable | 4c9kB-1vkoA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 398LEU A 401GLY A 402VAL A 369VAL A 366 | None | 1.10A | 4c9kB-1xb7A:undetectable | 4c9kB-1xb7A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xvx | YFUA (Yersiniaenterocolitica) |
PF13343(SBP_bac_6) | 5 | THR A 253LEU A 60GLY A 233VAL A 271VAL A 87 | None | 1.43A | 4c9kB-1xvxA:undetectable | 4c9kB-1xvxA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xvy | SFUA (Yersiniaenterocolitica) |
PF13343(SBP_bac_6) | 5 | THR A 250LEU A 57GLY A 230VAL A 268VAL A 84 | None | 1.44A | 4c9kB-1xvyA:undetectable | 4c9kB-1xvyA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zjr | TRNA(GUANOSINE-2'-O-)-METHYLTRANSFERASE (Aquifexaeolicus) |
PF00588(SpoU_methylase)PF12105(SpoU_methylas_C) | 5 | TYR A 117GLY A 162THR A 45VAL A 51VAL A 49 | None | 1.11A | 4c9kB-1zjrA:undetectable | 4c9kB-1zjrA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zzm | PUTATIVEDEOXYRIBONUCLEASEYJJV (Escherichiacoli) |
PF01026(TatD_DNase) | 5 | LEU A 115LEU A 116GLY A 99VAL A 95VAL A 130 | None | 1.47A | 4c9kB-1zzmA:undetectable | 4c9kB-1zzmA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b25 | HYPOTHETICAL PROTEIN (Homo sapiens) |
PF08704(GCD14) | 5 | LEU A 73LEU A 119GLY A 116VAL A 131VAL A 167 | NoneNoneSAM A 601 (-3.5A)NoneNone | 1.36A | 4c9kB-2b25A:undetectable | 4c9kB-2b25A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cri | VESICLE-ASSOCIATEDMEMBRANEPROTEIN-ASSOCIATEDPROTEIN A (Mus musculus) |
PF00635(Motile_Sperm) | 5 | THR A 35LEU A 126LEU A 23VAL A 61VAL A 78 | None | 1.48A | 4c9kB-2criA:undetectable | 4c9kB-2criA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7u | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Thermusthermophilus) |
PF00202(Aminotran_3) | 5 | TRP A 394LEU A 417LEU A 420VAL A 350VAL A 359 | None | 1.34A | 4c9kB-2e7uA:undetectable | 4c9kB-2e7uA:23.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ego | GENERAL RECEPTOR FORPHOSPHOINOSITIDES1-ASSOCIATEDSCAFFOLD PROTEIN (Rattusnorvegicus) |
PF00595(PDZ) | 5 | THR A 185LEU A 101GLY A 147THR A 149VAL A 134 | None | 1.33A | 4c9kB-2egoA:undetectable | 4c9kB-2egoA:14.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | THR A 181LEU A 244GLY A 248THR A 252VAL A 396 | NoneHEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-3.4A)None | 1.31A | 4c9kB-2m56A:57.7 | 4c9kB-2m56A:44.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 7 | TYR A 96THR A 185LEU A 244GLY A 248THR A 252VAL A 295VAL A 396 | CAM A 502 (-4.5A)NoneHEM A 501 (-4.5A)HEM A 501 (-3.9A)HEM A 501 (-3.4A)HEM A 501 (-4.6A)None | 0.41A | 4c9kB-2m56A:57.7 | 4c9kB-2m56A:44.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oga | TRANSAMINASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 5 | THR A 206LEU A 218GLY A 77VAL A 162VAL A 184 | None | 1.27A | 4c9kB-2ogaA:undetectable | 4c9kB-2ogaA:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qa1 | POLYKETIDE OXYGENASEPGAE (Streptomycessp. PGA64) |
PF01494(FAD_binding_3) | 5 | LEU A 17LEU A 298GLY A 299VAL A 306VAL A 305 | None | 1.21A | 4c9kB-2qa1A:undetectable | 4c9kB-2qa1A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rq6 | ATP SYNTHASE EPSILONCHAIN (Thermosynechococcuselongatus) |
PF00401(ATP-synt_DE)PF02823(ATP-synt_DE_N) | 5 | THR A 42LEU A 24LEU A 31GLY A 32VAL A 69 | None | 1.14A | 4c9kB-2rq6A:undetectable | 4c9kB-2rq6A:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rq7 | ATP SYNTHASE EPSILONCHAIN (Spinaciaoleracea;Thermosynechococcuselongatus) |
PF00401(ATP-synt_DE)PF02823(ATP-synt_DE_N) | 5 | LEU A 24LEU A 31GLY A 32VAL A 74VAL A 69 | None | 1.28A | 4c9kB-2rq7A:undetectable | 4c9kB-2rq7A:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2waa | XYLAN ESTERASE,PUTATIVE, AXE2C (Cellvibriojaponicus) |
PF13472(Lipase_GDSL_2) | 5 | TYR A 252THR A 271LEU A 202GLY A 139THR A 143 | None | 1.45A | 4c9kB-2waaA:undetectable | 4c9kB-2waaA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkk | TOPOISOMERASE IV (Acinetobacterbaumannii) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 5 | THR A1018LEU A 572LEU A 576GLY A 575VAL A 484 | None | 1.42A | 4c9kB-2xkkA:undetectable | 4c9kB-2xkkA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | LEU A 226GLY A 230THR A 234VAL A 277VAL A 381 | HEM A1400 (-4.4A)PG4 A1399 ( 3.2A)HEM A1400 (-3.7A)HEM A1400 (-4.5A)None | 0.85A | 4c9kB-2xkrA:44.2 | 4c9kB-2xkrA:26.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xqh | IMMUNOGLOBULIN-BINDING PROTEIN EIBD (Escherichiacoli) |
PF05658(YadA_head) | 5 | THR A 198LEU A 214GLY A 215THR A 204VAL A 186 | None | 1.45A | 4c9kB-2xqhA:undetectable | 4c9kB-2xqhA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1q | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | THR A 39LEU A 75LEU A 74VAL A 47VAL A 43 | None | 1.41A | 4c9kB-2z1qA:undetectable | 4c9kB-2z1qA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a4t | PUTATIVEMETHYLTRANSFERASEMJ0026 (Methanocaldococcusjannaschii) |
PF01189(Methyltr_RsmB-F) | 5 | THR A 136LEU A 124GLY A 95THR A 99VAL A 133 | NoneNoneSFG A 500 (-4.0A)NoneNone | 1.38A | 4c9kB-3a4tA:undetectable | 4c9kB-3a4tA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3d | PUTATIVE MORPHINEDEHYDROGENASE (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 5 | THR A 50LEU A 107LEU A 105GLY A 61VAL A 24 | None | 1.10A | 4c9kB-3b3dA:undetectable | 4c9kB-3b3dA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtt | NADP OXIDOREDUCTASE (Arthrobactersp. FB24) |
PF03807(F420_oxidored) | 5 | THR A 142LEU A 184LEU A 181VAL A 76VAL A 102 | None | 1.01A | 4c9kB-3dttA:undetectable | 4c9kB-3dttA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fha | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE (Glutamicibacterprotophormiae) |
PF03644(Glyco_hydro_85) | 5 | TRP A 282LEU A 55LEU A 296GLY A 297VAL A 271 | None | 1.25A | 4c9kB-3fhaA:undetectable | 4c9kB-3fhaA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fn4 | NAD-DEPENDENTFORMATEDEHYDROGENASE (Moraxella sp.) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 217GLY A 195THR A 252VAL A 155VAL A 158 | None | 1.25A | 4c9kB-3fn4A:undetectable | 4c9kB-3fn4A:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 274LEU A 191GLY A 226VAL A 240VAL A 217 | None | 1.34A | 4c9kB-3g1uA:undetectable | 4c9kB-3g1uA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i09 | PERIPLASMICBRANCHED-CHAIN AMINOACID-BINDING PROTEIN (Burkholderiamallei) |
PF13458(Peripla_BP_6) | 5 | THR A 154LEU A 224LEU A 252GLY A 223VAL A 158 | None | 1.48A | 4c9kB-3i09A:undetectable | 4c9kB-3i09A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4k | MUCONATE LACTONIZINGENZYME (Corynebacteriumglutamicum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | TYR A 340LEU A 336GLY A 332THR A 303VAL A 54 | TYR A 340 ( 1.3A)LEU A 336 ( 0.6A)GLY A 332 ( 0.0A)THR A 303 (-0.8A)VAL A 54 ( 0.6A) | 1.26A | 4c9kB-3i4kA:undetectable | 4c9kB-3i4kA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igz | COFACTOR-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Leishmaniamexicana) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 5 | THR B 464LEU B 82GLY B 78VAL B 57VAL B 501 | None | 1.49A | 4c9kB-3igzB:undetectable | 4c9kB-3igzB:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iy7 | FRAGMENT FROMNEUTRALIZINGANTIBODY F (HEAVYCHAIN) (Rattusnorvegicus) |
PF07686(V-set) | 5 | TYR B 193THR B 190LEU B 167VAL B 112VAL B 220 | None | 1.36A | 4c9kB-3iy7B:undetectable | 4c9kB-3iy7B:12.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lda | DNA REPAIR PROTEINRAD51 (Saccharomycescerevisiae) |
PF08423(Rad51)PF14520(HHH_5) | 5 | THR A 356LEU A 167LEU A 171GLY A 174VAL A 322 | None | 1.08A | 4c9kB-3ldaA:undetectable | 4c9kB-3ldaA:24.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwn | PHYCOERYTHRIN (Phormidiumtenue) |
PF00502(Phycobilisome) | 5 | THR A1134LEU A1159LEU A1156VAL A1052VAL A1051 | NoneNoneNoneNoneCYC A3002 ( 4.5A) | 1.26A | 4c9kB-3mwnA:undetectable | 4c9kB-3mwnA:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nd1 | PRECORRIN-6ASYNTHASE/COBFPROTEIN (Rhodobactercapsulatus) |
PF00590(TP_methylase) | 5 | TYR A 246THR A 166LEU A 171GLY A 175VAL A 164 | None | 1.42A | 4c9kB-3nd1A:undetectable | 4c9kB-3nd1A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00365(PFK) | 5 | LEU A 740LEU A 743THR A 782VAL A 787VAL A 824 | None | 1.19A | 4c9kB-3o8oA:undetectable | 4c9kB-3o8oA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | THR A 324LEU A 241GLY A 276VAL A 290VAL A 267 | None | 1.35A | 4c9kB-3oneA:undetectable | 4c9kB-3oneA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | THR A 333LEU A 337LEU A 335VAL A 368VAL A 215 | None | 1.45A | 4c9kB-3pfeA:undetectable | 4c9kB-3pfeA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzr | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Vibrio cholerae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 346LEU A 143GLY A 144VAL A 304VAL A 329 | None | 1.46A | 4c9kB-3pzrA:undetectable | 4c9kB-3pzrA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pzr | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Vibrio cholerae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 346LEU A 146LEU A 143GLY A 144VAL A 304 | None | 1.23A | 4c9kB-3pzrA:undetectable | 4c9kB-3pzrA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sh5 | LG3 PEPTIDE (Homo sapiens) |
PF00054(Laminin_G_1) | 5 | THR A 40LEU A 73LEU A 68GLY A 67VAL A 160 | None | 1.09A | 4c9kB-3sh5A:undetectable | 4c9kB-3sh5A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw3 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Burkholderiathailandensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | THR A 350LEU A 146LEU A 143GLY A 144VAL A 308 | None | 1.29A | 4c9kB-3uw3A:undetectable | 4c9kB-3uw3A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9a | PUTATIVEUNCHARACTERIZEDPROTEIN (Coprinopsiscinerea) |
no annotation | 5 | TYR A 179LEU A 144GLY A 156VAL A 202VAL A 203 | None | 1.09A | 4c9kB-3w9aA:undetectable | 4c9kB-3w9aA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 5 | LEU A 229GLY A 233THR A 237VAL A 280VAL A 383 | HEM A1402 ( 4.6A)EDO A1406 ( 3.4A)HEM A1402 (-3.7A)HEM A1402 (-4.4A)None | 0.90A | 4c9kB-3zbyA:41.7 | 4c9kB-3zbyA:28.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | THR A 187GLY A 256THR A 260VAL A 302VAL A 404 | NoneHEM A1418 (-3.8A)HEM A1418 (-3.6A)HEM A1418 ( 4.5A)GOL A1419 (-3.5A) | 1.46A | 4c9kB-4c9mA:71.3 | 4c9kB-4c9mA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 9 | TRP A 89TYR A 98THR A 187LEU A 252LEU A 255GLY A 256THR A 260VAL A 303VAL A 404 | NoneNoneNoneHEM A1418 (-4.0A)GOL A1419 ( 4.9A)HEM A1418 (-3.8A)HEM A1418 (-3.6A)GOL A1419 (-3.9A)GOL A1419 (-3.5A) | 0.21A | 4c9kB-4c9mA:71.3 | 4c9kB-4c9mA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | LEU A 250GLY A 254THR A 258VAL A 301VAL A 402 | HEM A 501 (-4.3A)PEG A 502 (-3.8A)HEM A 501 (-3.7A)PEG A 502 ( 4.5A)None | 0.94A | 4c9kB-4dxyA:55.2 | 4c9kB-4dxyA:61.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dxy | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | THR A 185LEU A 250LEU A 253GLY A 254THR A 258 | NoneHEM A 501 (-4.3A)NonePEG A 502 (-3.8A)HEM A 501 (-3.7A) | 1.01A | 4c9kB-4dxyA:55.2 | 4c9kB-4dxyA:61.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpg | PROTEASE 1 (Achromobacterlyticus) |
PF00089(Trypsin) | 5 | TRP A 182THR A 189LEU A 209GLY A 195THR A 37 | None | 1.48A | 4c9kB-4gpgA:undetectable | 4c9kB-4gpgA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3g | BETA-GLUCOSIDASE (Streptomycesvenezuelae) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | TYR A 573THR A 590GLY A 440THR A 554VAL A 546 | NoneSO4 A 904 (-4.5A)NoneNoneNone | 1.29A | 4c9kB-4i3gA:undetectable | 4c9kB-4i3gA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7p | ANTIBODY 10C4 FABFRAGMENT HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | TYR H 122GLY H 118THR H 204VAL H 197VAL H 206 | None | 1.47A | 4c9kB-4k7pH:undetectable | 4c9kB-4k7pH:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke4 | HYDROXYCINNAMOYL-COA:SHIKIMATEHYDROXYCINNAMOYLTRANSFERASE (Sorghum bicolor) |
PF02458(Transferase) | 5 | LEU A 295LEU A 381GLY A 382VAL A 417VAL A 429 | None | 1.33A | 4c9kB-4ke4A:undetectable | 4c9kB-4ke4A:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kmh | SUPPRESSOR OF FUSEDHOMOLOG (Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C) | 5 | LEU A 98GLY A 33THR A 190VAL A 188VAL A 195 | None | 1.42A | 4c9kB-4kmhA:undetectable | 4c9kB-4kmhA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4x | AMPHI (Streptomycesnodosus) |
PF08659(KR) | 5 | THR A 283LEU A 400LEU A 396VAL A 306VAL A 308 | None | 1.24A | 4c9kB-4l4xA:undetectable | 4c9kB-4l4xA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5b | COBALAMINBIOSYNTHESIS PROTEINCBIM (Caldanaerobactersubterraneus) |
PF01891(CbiM) | 5 | THR A 77LEU A 87LEU A 74GLY A 70THR A 202 | HEZ A 312 (-4.0A)NoneNoneNoneNone | 1.34A | 4c9kB-4m5bA:undetectable | 4c9kB-4m5bA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfi | SN-GLYCEROL-3-PHOSPHATE ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN USPB (Mycobacteriumtuberculosis) |
PF13416(SBP_bac_8) | 5 | THR A 331LEU A 99LEU A 309GLY A 308VAL A 348 | None | 1.05A | 4c9kB-4mfiA:undetectable | 4c9kB-4mfiA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 5 | THR A 234LEU A 230GLY A 199VAL A 371VAL A 374 | None | 1.33A | 4c9kB-4mnrA:undetectable | 4c9kB-4mnrA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk7 | SERINE/THREONINE-PROTEIN KINASE PLK4 (Drosophilamelanogaster) |
no annotation | 5 | LEU A 409GLY A 412THR A 391VAL A 495VAL A 492 | None | 1.14A | 4c9kB-4nk7A:undetectable | 4c9kB-4nk7A:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nsy | LYSYL ENDOPEPTIDASE (Lysobacterenzymogenes) |
PF13365(Trypsin_2) | 5 | TRP A 182THR A 189LEU A 209GLY A 195THR A 37 | None2OY A 301 (-3.6A)2OY A 301 ( 4.2A)NoneNone | 1.48A | 4c9kB-4nsyA:undetectable | 4c9kB-4nsyA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oh0 | BETA-LACTAMASEOXA-58 (Acinetobacterbaumannii) |
PF00905(Transpeptidase) | 5 | THR A 59LEU A 274GLY A 275VAL A 238VAL A 246 | None | 1.04A | 4c9kB-4oh0A:undetectable | 4c9kB-4oh0A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0e | MAF-LIKE PROTEINYHDE (Escherichiacoli) |
PF02545(Maf) | 5 | LEU A 16LEU A 173GLY A 172THR A 71VAL A 120 | None | 1.29A | 4c9kB-4p0eA:undetectable | 4c9kB-4p0eA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s1p | UNCHARACTERIZEDPROTEIN (Slackiaheliotrinireducens) |
PF13472(Lipase_GDSL_2) | 5 | TYR A 80THR A 103LEU A 38GLY A 7THR A 11 | None | 1.10A | 4c9kB-4s1pA:undetectable | 4c9kB-4s1pA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 5 | LEU A 17LEU A 298GLY A 299VAL A 306VAL A 305 | None | 1.20A | 4c9kB-4x4jA:undetectable | 4c9kB-4x4jA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyl | RPHYB PROTEIN (Rhodopseudomonaspalustris) |
PF00072(Response_reg) | 5 | TYR A 129LEU A 120LEU A 99VAL A 10VAL A 12 | None | 1.44A | 4c9kB-4zylA:undetectable | 4c9kB-4zylA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | EUKARYOTICTRANSLATIONINITIATION FACTOR 6 (Dictyosteliumdiscoideum) |
PF01912(eIF-6) | 5 | LEU I 70LEU I 71GLY I 65THR I 110VAL I 135 | None | 1.35A | 4c9kB-5anbI:undetectable | 4c9kB-5anbI:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT ALPHA (Schizosaccharomycespombe) |
PF01008(IF-2B) | 5 | THR A 141LEU A 153LEU A 152THR A 189VAL A 166 | None | 1.20A | 4c9kB-5b04A:undetectable | 4c9kB-5b04A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Geobactersulfurreducens) |
PF13847(Methyltransf_31) | 5 | LEU A 26LEU A 29GLY A 30VAL A 41VAL A 107 | None | 0.73A | 4c9kB-5bp7A:undetectable | 4c9kB-5bp7A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmn | HOMOCYSTEINES-METHYLTRANSFERASE (Escherichiacoli) |
PF02574(S-methyl_trans) | 5 | THR A 246LEU A 239LEU A 250GLY A 226VAL A 213 | None | 1.29A | 4c9kB-5dmnA:undetectable | 4c9kB-5dmnA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ebb | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Homo sapiens) |
PF00149(Metallophos) | 5 | TYR A 168LEU A 160LEU A 149GLY A 150VAL A 125 | None | 1.39A | 4c9kB-5ebbA:undetectable | 4c9kB-5ebbA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epe | SAM-DEPENDENTMETHYLTRANSFERASE (Thiobacillusdenitrificans) |
PF13847(Methyltransf_31) | 5 | LEU A 25LEU A 28GLY A 29VAL A 40VAL A 106 | None | 0.71A | 4c9kB-5epeA:undetectable | 4c9kB-5epeA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exk | LIPOYL SYNTHASE (Mycobacteriumtuberculosis) |
PF04055(Radical_SAM)PF16881(LIAS_N) | 5 | THR A 139LEU A 98LEU A 135GLY A 77VAL A 106 | None | 1.36A | 4c9kB-5exkA:undetectable | 4c9kB-5exkA:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffp | IMMUNITY 23 FAMILYPROTEIN (Burkholderiadolosa) |
PF15593(Imm42) | 5 | LEU A 105LEU A 29GLY A 30VAL A 148VAL A 151 | None | 1.31A | 4c9kB-5ffpA:undetectable | 4c9kB-5ffpA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frs | SISTER CHROMATIDCOHESION PROTEINPDS5 (Saccharomycescerevisiae) |
PF12717(Cnd1) | 5 | TYR A 157LEU A 223LEU A 175GLY A 176VAL A 185 | None | 1.42A | 4c9kB-5frsA:undetectable | 4c9kB-5frsA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGSFAD-BINDING SUBUNIT (Escherichiacoli) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | THR C 710LEU C 725LEU C 728GLY C 600VAL C 706 | None | 1.46A | 4c9kB-5g5gC:undetectable | 4c9kB-5g5gC:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gja | 1-AMINOCYCLOPROPANE-1-CARBOXYLATEOXIDASE 2 (Arabidopsisthaliana) |
PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 5 | TRP A 89LEU A 72GLY A 76VAL A 84VAL A 87 | None | 1.25A | 4c9kB-5gjaA:undetectable | 4c9kB-5gjaA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gje | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 6 (Homo sapiens) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 5 | TRP A 220LEU A 239GLY A 238VAL A 200VAL A 201 | None | 1.37A | 4c9kB-5gjeA:undetectable | 4c9kB-5gjeA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqj | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Paraburkholderiagraminis) |
PF13407(Peripla_BP_4) | 5 | THR A 206LEU A 213GLY A 215VAL A 227VAL A 203 | None | 1.41A | 4c9kB-5hqjA:undetectable | 4c9kB-5hqjA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxm | PRIB (Streptomycessp. RM-5-8) |
PF11991(Trp_DMAT) | 5 | THR A 91LEU A 35GLY A 36VAL A 111VAL A 93 | None | 0.78A | 4c9kB-5jxmA:undetectable | 4c9kB-5jxmA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kar | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3B (Mus musculus) |
PF00149(Metallophos) | 5 | TYR A 151LEU A 132GLY A 133VAL A 108VAL A 112 | None | 1.35A | 4c9kB-5karA:undetectable | 4c9kB-5karA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kju | SHIKIMATEO-HYDROXYCINNAMOYLTRANSFERASE (Arabidopsisthaliana) |
PF02458(Transferase) | 5 | LEU A 279LEU A 366GLY A 367VAL A 402VAL A 414 | None | 1.21A | 4c9kB-5kjuA:undetectable | 4c9kB-5kjuA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfh | METHIONYL-TRNASYNTHETASE, PUTATIVE (Trypanosomabrucei) |
no annotation | 5 | THR A 710LEU A 606LEU A 610GLY A 611VAL A 723 | None | 1.04A | 4c9kB-5nfhA:undetectable | 4c9kB-5nfhA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u09 | CANNABINOID RECEPTOR1,GLGA GLYCOGENSYNTHASE (Homo sapiens;Pyrococcusabyssi) |
PF00001(7tm_1)PF00534(Glycos_transf_1) | 5 | TRP A 279THR A 283LEU A 359LEU A 360GLY A 357 | NoneNone7DY A1210 ( 4.9A)NoneNone | 1.37A | 4c9kB-5u09A:undetectable | 4c9kB-5u09A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5umx | GLYOXALASE/BLEOMYCINRESISANCEPROTEIN/DIOXYGENASE (Streptomycessp. CB03234) |
no annotation | 5 | LEU A 73LEU A 116GLY A 115VAL A 90VAL A 92 | None | 1.34A | 4c9kB-5umxA:undetectable | 4c9kB-5umxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vj1 | MDCA (Pseudomonasaeruginosa) |
PF16957(Mal_decarbox_Al) | 5 | THR A 445LEU A 126LEU A 121GLY A 118VAL A 441 | None | 1.36A | 4c9kB-5vj1A:undetectable | 4c9kB-5vj1A:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wwl | CENTROMERE PROTEINMIS12KINETOCHORE PROTEINNNF1 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
no annotationno annotation | 5 | THR N 19LEU N 12LEU N 16THR M 21VAL M 64 | None | 1.49A | 4c9kB-5wwlN:undetectable | 4c9kB-5wwlN:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xra | CANNABINOID RECEPTOR1,FLAVODOXIN,CANNABINOID RECEPTOR 1 (Desulfovibriovulgaris;Homo sapiens) |
PF00001(7tm_1)PF00258(Flavodoxin_1) | 5 | TRP A 279LEU A 359LEU A 360GLY A 357VAL A 204 | 8D3 A 602 ( 3.5A)8D3 A 602 ( 4.5A)NoneNoneNone | 1.29A | 4c9kB-5xraA:undetectable | 4c9kB-5xraA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 5 | LEU A 81LEU A 80GLY A 79THR A 4VAL A 22 | None | 1.28A | 4c9kB-6bogA:undetectable | 4c9kB-6bogA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 5 | LEU A 81LEU A 80GLY A 79THR A 4VAL A 22 | None | 1.34A | 4c9kB-6bogA:undetectable | 4c9kB-6bogA:undetectable |